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Fusion gene ID: 41640 |
FusionGeneSummary for VPS72_ROBO2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: VPS72_ROBO2 | Fusion gene ID: 41640 | Hgene | Tgene | Gene symbol | VPS72 | ROBO2 | Gene ID | 6944 | 6092 |
| Gene name | vacuolar protein sorting 72 homolog | roundabout guidance receptor 2 | |
| Synonyms | CFL1|Swc2|TCFL1|YL-1|YL1 | SAX3 | |
| Cytomap | 1q21.3 | 3p12.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | vacuolar protein sorting-associated protein 72 homologtranscription factor-like 1transformation suppressor gene YL-1 | roundabout homolog 2roundabout, axon guidance receptor, homolog 2 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q15906 | Q9HCK4 | |
| Ensembl transtripts involved in fusion gene | ENST00000354473, ENST00000496809, | ENST00000487694, ENST00000461745, ENST00000332191, ENST00000469233, | |
| Fusion gene scores | * DoF score | 8 X 7 X 4=224 | 8 X 8 X 6=384 |
| # samples | 8 | 8 | |
| ** MAII score | log2(8/224*10)=-1.48542682717024 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/384*10)=-2.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: VPS72 [Title/Abstract] AND ROBO2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ROBO2 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules | 12504588 |
| Tgene | ROBO2 | GO:0050772 | positive regulation of axonogenesis | 12504588 |
| Tgene | ROBO2 | GO:0050925 | negative regulation of negative chemotaxis | 11748139 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-91-A4BC-01A | VPS72 | chr1 | 151156793 | - | ROBO2 | chr3 | 77617464 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000354473 | ENST00000487694 | VPS72 | chr1 | 151156793 | - | ROBO2 | chr3 | 77617464 | + |
| In-frame | ENST00000354473 | ENST00000461745 | VPS72 | chr1 | 151156793 | - | ROBO2 | chr3 | 77617464 | + |
| In-frame | ENST00000354473 | ENST00000332191 | VPS72 | chr1 | 151156793 | - | ROBO2 | chr3 | 77617464 | + |
| 5CDS-intron | ENST00000354473 | ENST00000469233 | VPS72 | chr1 | 151156793 | - | ROBO2 | chr3 | 77617464 | + |
| 5UTR-3CDS | ENST00000496809 | ENST00000487694 | VPS72 | chr1 | 151156793 | - | ROBO2 | chr3 | 77617464 | + |
| 5UTR-3CDS | ENST00000496809 | ENST00000461745 | VPS72 | chr1 | 151156793 | - | ROBO2 | chr3 | 77617464 | + |
| 5UTR-3CDS | ENST00000496809 | ENST00000332191 | VPS72 | chr1 | 151156793 | - | ROBO2 | chr3 | 77617464 | + |
| 5UTR-intron | ENST00000496809 | ENST00000469233 | VPS72 | chr1 | 151156793 | - | ROBO2 | chr3 | 77617464 | + |
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FusionProtFeatures for VPS72_ROBO2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| VPS72 | ROBO2 |
| Deposition-and-exchange histone chaperone specific forH2AFZ, specifically chaperones H2AFZ and deposits it intonucleosomes. As component of the SRCAP complex, mediates the ATP-dependent exchange of histone H2AFZ/H2B dimers for nucleosomalH2A/H2B, leading to transcriptional regulation of selected genesby chromatin remodeling. {ECO:0000269|PubMed:26974126}. | Receptor for SLIT2, and probably SLIT1, which arethought to act as molecular guidance cue in cellular migration,including axonal navigation at the ventral midline of the neuraltube and projection of axons to different regions during neuronaldevelopment. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | VPS72 | chr1:151156793 | chr3:77617464 | ENST00000354473 | - | 4 | 6 | 22_77 | 187 | 376 | Compositional bias | Note=Asp/Glu-rich (acidic) |
| Tgene | >ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000461745 | + | 11 | 26 | 637_735 | 616 | 1379 | Domain | Fibronectin type-III 2 |
| Tgene | >ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000461745 | + | 11 | 26 | 739_836 | 616 | 1379 | Domain | Fibronectin type-III 3 |
| Tgene | >ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000487694 | + | 12 | 27 | 637_735 | 632 | 1395 | Domain | Fibronectin type-III 2 |
| Tgene | >ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000487694 | + | 12 | 27 | 739_836 | 632 | 1395 | Domain | Fibronectin type-III 3 |
| Tgene | >ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000461745 | + | 11 | 26 | 881_1378 | 616 | 1379 | Topological domain | Cytoplasmic |
| Tgene | >ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000487694 | + | 12 | 27 | 881_1378 | 632 | 1395 | Topological domain | Cytoplasmic |
| Tgene | >ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000461745 | + | 11 | 26 | 860_880 | 616 | 1379 | Transmembrane | Helical |
| Tgene | >ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000487694 | + | 12 | 27 | 860_880 | 632 | 1395 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >VPS72 | chr1:151156793 | chr3:77617464 | ENST00000354473 | - | 4 | 6 | 333_354 | 187 | 376 | Compositional bias | Note=Pro-rich |
| Hgene | >VPS72 | chr1:151156793 | chr3:77617464 | ENST00000354473 | - | 4 | 6 | 341_350 | 187 | 376 | Compositional bias | Note=Poly-Pro |
| Hgene | >VPS72 | chr1:151156793 | chr3:77617464 | ENST00000354473 | - | 4 | 6 | 156_206 | 187 | 376 | DNA binding | Ontology_term=ECO:0000255 |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000461745 | + | 11 | 26 | 133_220 | 616 | 1379 | Domain | Note=Ig-like C2-type 2 |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000461745 | + | 11 | 26 | 225_309 | 616 | 1379 | Domain | Note=Ig-like C2-type 3 |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000461745 | + | 11 | 26 | 314_409 | 616 | 1379 | Domain | Note=Ig-like C2-type 4 |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000461745 | + | 11 | 26 | 31_127 | 616 | 1379 | Domain | Note=Ig-like C2-type 1 |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000461745 | + | 11 | 26 | 418_504 | 616 | 1379 | Domain | Note=Ig-like C2-type 5 |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000461745 | + | 11 | 26 | 524_618 | 616 | 1379 | Domain | Fibronectin type-III 1 |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000487694 | + | 12 | 27 | 133_220 | 632 | 1395 | Domain | Note=Ig-like C2-type 2 |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000487694 | + | 12 | 27 | 225_309 | 632 | 1395 | Domain | Note=Ig-like C2-type 3 |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000487694 | + | 12 | 27 | 314_409 | 632 | 1395 | Domain | Note=Ig-like C2-type 4 |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000487694 | + | 12 | 27 | 31_127 | 632 | 1395 | Domain | Note=Ig-like C2-type 1 |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000487694 | + | 12 | 27 | 418_504 | 632 | 1395 | Domain | Note=Ig-like C2-type 5 |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000487694 | + | 12 | 27 | 524_618 | 632 | 1395 | Domain | Fibronectin type-III 1 |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000461745 | + | 11 | 26 | 22_859 | 616 | 1379 | Topological domain | Extracellular |
| Tgene | ROBO2 | chr1:151156793 | chr3:77617464 | ENST00000487694 | + | 12 | 27 | 22_859 | 632 | 1395 | Topological domain | Extracellular |
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FusionGeneSequence for VPS72_ROBO2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_VPS72_ENST00000354473_chr1_151156793_-_ROBO2_ENST00000487694_chr3_77617464_+_950aa MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYK EPLKSLRPRKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITE ELNLRSLDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVL VNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHIN KTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIW LYWRRKKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPPVPGQGDKTATMLS DGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSS KPQKNNGSTWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRGVASSPAISFGQQS TATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQ TPGSSMDNLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALVPYSKPSFPSPGGH >In-frame_VPS72_ENST00000354473_chr1_151156793_-_ROBO2_ENST00000461745_chr3_77617464_+_950aa MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYK EPLKSLRPRKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITE ELNLRSLDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVL VNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHIN KTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIW LYWRRKKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPPVPGQGDKTATMLS DGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSS KPQKNNGSTWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRGVASSPAISFGQQS TATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQ TPGSSMDNLDSSVTGKAFTSSQRPRPTSPFSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALVPYSKPSFPSPGGH >In-frame_VPS72_ENST00000354473_chr1_151156793_-_ROBO2_ENST00000332191_chr3_77617464_+_1011aa MSLAGGRAPRKTAGNRLSGLLEAEEEDEFYQTTYGGFTEESGDDEYQGDQSDTEDEVDSDFDIDEGDEPSSDGEAEEPRRKRRVVTKAYK EPLKSLRPRKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQSRRRKGPHCERPLTQEELLREAKITE ELNLRSLDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVL VNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKIWCLGNETRFHIN KTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSEPQPIIIGRRNEVVITENNNSITEQITDVVKQPAFIAGIGGACWVILMGFSIW LYWRRKKRKGLSNYAVTFQRGDGGLMSNGSRPGLLNAGDPSYPWLADSWPATSLPVNNSNSGPNEIGNFGRGDVLPPVPGQGDKTATMLS DGAIYSSIDFTTKTSYNSSSQITQATPYATTQILHSNSIHELAVDLPDPQWKSSIQQKTDLMGFGYSLPDQNKGNNGGKGGKKKKNKNSS KPQKNNGSTWANVPLPPPPVQPLPGTELEHYAVEQQENGYDSDSWCPPLPVQTYLHQGLEDELEEDDDRVPTPPVRGVASSPAISFGQQS TATLTPSPREEMQPMLQAHLDELTRAYQFDIAKQTWHIQSNNQPPQPPVPPLGYVSGALISDLETDVADDDADDEEEALEIPRPLRALDQ TPGSSMDNLDSSVTGSMVNGWGSASDEDRNFSSHRSSVGSSSDGSIFASGSFAQALVAAADKAGFRLDGTSLTRTGKAFTSSQRPRPTSP FSTDSNTSAALSQSQRPRPTKKHKGGRMDQQPALPHRREGMTDEEALVPYSKPSFPSPGGHSSSGTASSKGSTGPRKTEVLRAGHQRNAS |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_VPS72_ENST00000354473_chr1_151156793_-_ROBO2_ENST00000487694_chr3_77617464_+_2850nt ATGAGTTTGGCTGGGGGCCGGGCACCCCGGAAGACCGCTGGGAACCGGCTTTCTGGGCTTTTGGAGGCAGAGGAGGAAGATGAGTTCTAC CAGACGACTTATGGGGGTTTCACAGAGGAATCCGGAGATGATGAGTATCAAGGGGACCAGTCAGACACAGAGGACGAAGTGGACTCTGAC TTTGACATTGATGAAGGGGATGAACCATCCAGTGATGGAGAAGCAGAAGAGCCAAGAAGGAAGCGCCGAGTAGTCACCAAGGCCTATAAG GAACCTCTCAAGAGCTTAAGGCCTCGAAAGGTCAACACCCCGGCTGGTAGCTCTCAGAAGGCGCGAGAAGAGAAGGCACTACTGCCATTA GAACTACAAGATGACGGCTCTGACAGTCGGAAGTCTATGCGTCAGTCTACAGCTGAGCATACACGACAAACGTTCCTTCGGGTACAGGAG AGGCAGGGCCAGTCAAGACGGCGAAAGGGGCCCCACTGTGAGCGGCCACTAACCCAGGAGGAACTGCTCCGGGAGGCCAAGATCACAGAA GAGCTTAATTTACGGTCACTGGATATCAGCCCACCAGCACAAGGAGTGGACCACAGGCAAGTGCAGAAAGAGCTAGGAGATGTCCTTGTC CGTCTTCATAATCCAGTTGTGCTGACTCCCACCACGGTTCAGGTCACATGGACGGTTGATCGCCAACCCCAGTTTATCCAAGGCTACCGA GTGATGTATCGTCAGACTTCAGGTCTGCAGGCGACATCTTCGTGGCAGAATTTAGATGCCAAAGTCCCGACTGAACGAAGTGCTGTCTTA GTCAACCTGAAAAAGGGGGTGACTTATGAAATTAAAGTACGGCCATATTTTAATGAGTTCCAAGGAATGGATAGTGAATCTAAAACGGTT CGTACTACTGAAGAAGCCCCAAGTGCCCCACCACAGTCTGTCACTGTACTGACAGTTGGAAGCTACAATAGCACAAGTATTAGTGTTTCC TGGGATCCTCCTCCTCCAGATCACCAGAATGGAATTATCCAAGAATACAAGATCTGGTGTCTAGGAAATGAAACGCGATTCCATATCAAC AAAACTGTGGATGCAGCCATTCGGTCCGTAATAATTGGTGGATTATTCCCAGGTATTCAATACCGGGTAGAGGTTGCAGCTAGTACCAGT GCAGGGGTTGGAGTAAAGAGTGAGCCACAGCCAATAATAATCGGGAGACGCAATGAAGTTGTCATTACTGAAAACAATAACAGCATAACT GAGCAAATCACTGATGTGGTGAAGCAACCAGCCTTTATAGCTGGTATTGGTGGTGCCTGCTGGGTAATTCTGATGGGTTTTAGCATATGG TTGTATTGGCGAAGAAAGAAGAGGAAGGGACTCAGTAATTATGCTGTTACGTTTCAAAGAGGAGATGGAGGACTAATGAGCAATGGAAGC CGTCCAGGTCTTCTCAATGCTGGTGATCCCAGCTATCCATGGCTTGCTGATTCTTGGCCAGCCACGAGCTTGCCAGTAAATAATAGCAAC AGTGGCCCAAATGAGATTGGAAATTTTGGCCGTGGAGATGTGCTGCCACCAGTTCCAGGCCAAGGGGATAAAACAGCAACGATGCTCTCA GATGGAGCCATTTATAGTAGCATTGACTTCACTACCAAAACCAGTTACAACAGTTCCAGCCAAATAACACAGGCTACCCCATATGCCACG ACACAGATCTTGCATTCCAACAGCATACATGAATTGGCTGTCGATCTGCCTGATCCACAATGGAAAAGCTCAATTCAGCAAAAAACAGAT CTGATGGGATTTGGTTATTCTCTACCTGATCAGAACAAAGGTAACAATGGTGGGAAAGGTGGAAAAAAGAAGAAAAATAAAAACTCTTCT AAACCACAGAAAAACAATGGATCCACTTGGGCCAATGTCCCTCTACCTCCCCCCCCAGTCCAGCCCCTTCCTGGCACGGAGCTGGAACAC TATGCAGTGGAACAACAAGAAAATGGCTATGACAGTGATAGCTGGTGCCCACCATTGCCAGTACAAACTTACTTACACCAAGGTCTGGAA GATGAACTGGAAGAAGATGATGATAGGGTCCCAACACCTCCTGTTCGAGGCGTGGCTTCTTCTCCTGCTATCTCCTTTGGACAGCAGTCC ACTGCAACTCTTACTCCATCCCCACGGGAAGAGATGCAACCCATGCTGCAGGCTCACCTGGATGAGTTGACAAGAGCCTATCAGTTTGAT ATAGCAAAACAAACATGGCACATTCAAAGCAATAATCAACCTCCACAGCCTCCAGTTCCACCGTTAGGTTATGTGTCTGGAGCCTTGATT TCTGATTTGGAAACGGATGTTGCAGATGATGATGCCGACGACGAAGAGGAAGCTTTAGAAATCCCCAGGCCCCTGAGAGCACTGGACCAG ACTCCTGGATCCAGCATGGACAATCTAGACAGCTCTGTGACAGGAAAAGCCTTTACCTCCTCTCAAAGACCTCGACCTACCAGCCCATTT TCTACTGACAGTAACACCAGTGCAGCCCTGAGTCAAAGTCAGAGGCCTCGGCCCACTAAAAAACACAAGGGAGGGCGGATGGACCAACAA CCAGCATTGCCTCATCGAAGGGAAGGAATGACAGATGAGGAGGCCTTGGTGCCCTATAGCAAGCCCAGTTTCCCATCTCCAGGTGGCCAC AGCTCATCAGGAACAGCTTCTTCTAAGGGATCCACTGGACCTAGGAAAACCGAGGTGTTGAGAGCAGGCCACCAGCGCAATGCCAGCGAC >In-frame_VPS72_ENST00000354473_chr1_151156793_-_ROBO2_ENST00000461745_chr3_77617464_+_2850nt ATGAGTTTGGCTGGGGGCCGGGCACCCCGGAAGACCGCTGGGAACCGGCTTTCTGGGCTTTTGGAGGCAGAGGAGGAAGATGAGTTCTAC CAGACGACTTATGGGGGTTTCACAGAGGAATCCGGAGATGATGAGTATCAAGGGGACCAGTCAGACACAGAGGACGAAGTGGACTCTGAC TTTGACATTGATGAAGGGGATGAACCATCCAGTGATGGAGAAGCAGAAGAGCCAAGAAGGAAGCGCCGAGTAGTCACCAAGGCCTATAAG GAACCTCTCAAGAGCTTAAGGCCTCGAAAGGTCAACACCCCGGCTGGTAGCTCTCAGAAGGCGCGAGAAGAGAAGGCACTACTGCCATTA GAACTACAAGATGACGGCTCTGACAGTCGGAAGTCTATGCGTCAGTCTACAGCTGAGCATACACGACAAACGTTCCTTCGGGTACAGGAG AGGCAGGGCCAGTCAAGACGGCGAAAGGGGCCCCACTGTGAGCGGCCACTAACCCAGGAGGAACTGCTCCGGGAGGCCAAGATCACAGAA GAGCTTAATTTACGGTCACTGGATATCAGCCCACCAGCACAAGGAGTGGACCACAGGCAAGTGCAGAAAGAGCTAGGAGATGTCCTTGTC CGTCTTCATAATCCAGTTGTGCTGACTCCCACCACGGTTCAGGTCACATGGACGGTTGATCGCCAACCCCAGTTTATCCAAGGCTACCGA GTGATGTATCGTCAGACTTCAGGTCTGCAGGCGACATCTTCGTGGCAGAATTTAGATGCCAAAGTCCCGACTGAACGAAGTGCTGTCTTA GTCAACCTGAAAAAGGGGGTGACTTATGAAATTAAAGTACGGCCATATTTTAATGAGTTCCAAGGAATGGATAGTGAATCTAAAACGGTT CGTACTACTGAAGAAGCCCCAAGTGCCCCACCACAGTCTGTCACTGTACTGACAGTTGGAAGCTACAATAGCACAAGTATTAGTGTTTCC TGGGATCCTCCTCCTCCAGATCACCAGAATGGAATTATCCAAGAATACAAGATCTGGTGTCTAGGAAATGAAACGCGATTCCATATCAAC AAAACTGTGGATGCAGCCATTCGGTCCGTAATAATTGGTGGATTATTCCCAGGTATTCAATACCGGGTAGAGGTTGCAGCTAGTACCAGT GCAGGGGTTGGAGTAAAGAGTGAGCCACAGCCAATAATAATCGGGAGACGCAATGAAGTTGTCATTACTGAAAACAATAACAGCATAACT GAGCAAATCACTGATGTGGTGAAGCAACCAGCCTTTATAGCTGGTATTGGTGGTGCCTGCTGGGTAATTCTGATGGGTTTTAGCATATGG TTGTATTGGCGAAGAAAGAAGAGGAAGGGACTCAGTAATTATGCTGTTACGTTTCAAAGAGGAGATGGAGGACTAATGAGCAATGGAAGC CGTCCAGGTCTTCTCAATGCTGGTGATCCCAGCTATCCATGGCTTGCTGATTCTTGGCCAGCCACGAGCTTGCCAGTAAATAATAGCAAC AGTGGCCCAAATGAGATTGGAAATTTTGGCCGTGGAGATGTGCTGCCACCAGTTCCAGGCCAAGGGGATAAAACAGCAACGATGCTCTCA GATGGAGCCATTTATAGTAGCATTGACTTCACTACCAAAACCAGTTACAACAGTTCCAGCCAAATAACACAGGCTACCCCATATGCCACG ACACAGATCTTGCATTCCAACAGCATACATGAATTGGCTGTCGATCTGCCTGATCCACAATGGAAAAGCTCAATTCAGCAAAAAACAGAT CTGATGGGATTTGGTTATTCTCTACCTGATCAGAACAAAGGTAACAATGGTGGGAAAGGTGGAAAAAAGAAGAAAAATAAAAACTCTTCT AAACCACAGAAAAACAATGGATCCACTTGGGCCAATGTCCCTCTACCTCCCCCCCCAGTCCAGCCCCTTCCTGGCACGGAGCTGGAACAC TATGCAGTGGAACAACAAGAAAATGGCTATGACAGTGATAGCTGGTGCCCACCATTGCCAGTACAAACTTACTTACACCAAGGTCTGGAA GATGAACTGGAAGAAGATGATGATAGGGTCCCAACACCTCCTGTTCGAGGCGTGGCTTCTTCTCCTGCTATCTCCTTTGGACAGCAGTCC ACTGCAACTCTTACTCCATCCCCACGGGAAGAGATGCAACCCATGCTGCAGGCTCACCTGGATGAGTTGACAAGAGCCTATCAGTTTGAT ATAGCAAAACAAACATGGCACATTCAAAGCAATAATCAACCTCCACAGCCTCCAGTTCCACCGTTAGGTTATGTGTCTGGAGCCTTGATT TCTGATTTGGAAACGGATGTTGCAGATGATGATGCCGACGACGAAGAGGAAGCTTTAGAAATCCCCAGGCCCCTGAGAGCACTGGACCAG ACTCCTGGATCCAGCATGGACAATCTAGACAGCTCTGTGACAGGAAAAGCCTTTACCTCCTCTCAAAGACCTCGACCTACCAGCCCATTT TCTACTGACAGTAACACCAGTGCAGCCCTGAGTCAAAGTCAGAGGCCTCGGCCCACTAAAAAACACAAGGGAGGGCGGATGGACCAACAA CCAGCATTGCCTCATCGAAGGGAAGGAATGACAGATGAGGAGGCCTTGGTGCCCTATAGCAAGCCCAGTTTCCCATCTCCAGGTGGCCAC AGCTCATCAGGAACAGCTTCTTCTAAGGGATCCACTGGACCTAGGAAAACCGAGGTGTTGAGAGCAGGCCACCAGCGCAATGCCAGCGAC >In-frame_VPS72_ENST00000354473_chr1_151156793_-_ROBO2_ENST00000332191_chr3_77617464_+_3033nt ATGAGTTTGGCTGGGGGCCGGGCACCCCGGAAGACCGCTGGGAACCGGCTTTCTGGGCTTTTGGAGGCAGAGGAGGAAGATGAGTTCTAC CAGACGACTTATGGGGGTTTCACAGAGGAATCCGGAGATGATGAGTATCAAGGGGACCAGTCAGACACAGAGGACGAAGTGGACTCTGAC TTTGACATTGATGAAGGGGATGAACCATCCAGTGATGGAGAAGCAGAAGAGCCAAGAAGGAAGCGCCGAGTAGTCACCAAGGCCTATAAG GAACCTCTCAAGAGCTTAAGGCCTCGAAAGGTCAACACCCCGGCTGGTAGCTCTCAGAAGGCGCGAGAAGAGAAGGCACTACTGCCATTA GAACTACAAGATGACGGCTCTGACAGTCGGAAGTCTATGCGTCAGTCTACAGCTGAGCATACACGACAAACGTTCCTTCGGGTACAGGAG AGGCAGGGCCAGTCAAGACGGCGAAAGGGGCCCCACTGTGAGCGGCCACTAACCCAGGAGGAACTGCTCCGGGAGGCCAAGATCACAGAA GAGCTTAATTTACGGTCACTGGATATCAGCCCACCAGCACAAGGAGTGGACCACAGGCAAGTGCAGAAAGAGCTAGGAGATGTCCTTGTC CGTCTTCATAATCCAGTTGTGCTGACTCCCACCACGGTTCAGGTCACATGGACGGTTGATCGCCAACCCCAGTTTATCCAAGGCTACCGA GTGATGTATCGTCAGACTTCAGGTCTGCAGGCGACATCTTCGTGGCAGAATTTAGATGCCAAAGTCCCGACTGAACGAAGTGCTGTCTTA GTCAACCTGAAAAAGGGGGTGACTTATGAAATTAAAGTACGGCCATATTTTAATGAGTTCCAAGGAATGGATAGTGAATCTAAAACGGTT CGTACTACTGAAGAAGCCCCAAGTGCCCCACCACAGTCTGTCACTGTACTGACAGTTGGAAGCTACAATAGCACAAGTATTAGTGTTTCC TGGGATCCTCCTCCTCCAGATCACCAGAATGGAATTATCCAAGAATACAAGATCTGGTGTCTAGGAAATGAAACGCGATTCCATATCAAC AAAACTGTGGATGCAGCCATTCGGTCCGTAATAATTGGTGGATTATTCCCAGGTATTCAATACCGGGTAGAGGTTGCAGCTAGTACCAGT GCAGGGGTTGGAGTAAAGAGTGAGCCACAGCCAATAATAATCGGGAGACGCAATGAAGTTGTCATTACTGAAAACAATAACAGCATAACT GAGCAAATCACTGATGTGGTGAAGCAACCAGCCTTTATAGCTGGTATTGGTGGTGCCTGCTGGGTAATTCTGATGGGTTTTAGCATATGG TTGTATTGGCGAAGAAAGAAGAGGAAGGGACTCAGTAATTATGCTGTTACGTTTCAAAGAGGAGATGGAGGACTAATGAGCAATGGAAGC CGTCCAGGTCTTCTCAATGCTGGTGATCCCAGCTATCCATGGCTTGCTGATTCTTGGCCAGCCACGAGCTTGCCAGTAAATAATAGCAAC AGTGGCCCAAATGAGATTGGAAATTTTGGCCGTGGAGATGTGCTGCCACCAGTTCCAGGCCAAGGGGATAAAACAGCAACGATGCTCTCA GATGGAGCCATTTATAGTAGCATTGACTTCACTACCAAAACCAGTTACAACAGTTCCAGCCAAATAACACAGGCTACCCCATATGCCACG ACACAGATCTTGCATTCCAACAGCATACATGAATTGGCTGTCGATCTGCCTGATCCACAATGGAAAAGCTCAATTCAGCAAAAAACAGAT CTGATGGGATTTGGTTATTCTCTACCTGATCAGAACAAAGGTAACAATGGTGGGAAAGGTGGAAAAAAGAAGAAAAATAAAAACTCTTCT AAACCACAGAAAAACAATGGATCCACTTGGGCCAATGTCCCTCTACCTCCCCCCCCAGTCCAGCCCCTTCCTGGCACGGAGCTGGAACAC TATGCAGTGGAACAACAAGAAAATGGCTATGACAGTGATAGCTGGTGCCCACCATTGCCAGTACAAACTTACTTACACCAAGGTCTGGAA GATGAACTGGAAGAAGATGATGATAGGGTCCCAACACCTCCTGTTCGAGGCGTGGCTTCTTCTCCTGCTATCTCCTTTGGACAGCAGTCC ACTGCAACTCTTACTCCATCCCCACGGGAAGAGATGCAACCCATGCTGCAGGCTCACCTGGATGAGTTGACAAGAGCCTATCAGTTTGAT ATAGCAAAACAAACATGGCACATTCAAAGCAATAATCAACCTCCACAGCCTCCAGTTCCACCGTTAGGTTATGTGTCTGGAGCCTTGATT TCTGATTTGGAAACGGATGTTGCAGATGATGATGCCGACGACGAAGAGGAAGCTTTAGAAATCCCCAGGCCCCTGAGAGCACTGGACCAG ACTCCTGGATCCAGCATGGACAATCTAGACAGCTCTGTGACAGGTTCAATGGTAAATGGATGGGGCTCTGCATCTGATGAGGATCGTAAC TTTTCTAGTCATAGATCTAGTGTAGGTAGCTCCTCAGATGGCTCTATCTTTGCCAGCGGCAGTTTTGCACAAGCACTGGTGGCAGCAGCA GATAAAGCTGGTTTTAGGCTGGATGGAACCAGCCTTACAAGAACAGGAAAAGCCTTTACCTCCTCTCAAAGACCTCGACCTACCAGCCCA TTTTCTACTGACAGTAACACCAGTGCAGCCCTGAGTCAAAGTCAGAGGCCTCGGCCCACTAAAAAACACAAGGGAGGGCGGATGGACCAA CAACCAGCATTGCCTCATCGAAGGGAAGGAATGACAGATGAGGAGGCCTTGGTGCCCTATAGCAAGCCCAGTTTCCCATCTCCAGGTGGC CACAGCTCATCAGGAACAGCTTCTTCTAAGGGATCCACTGGACCTAGGAAAACCGAGGTGTTGAGAGCAGGCCACCAGCGCAATGCCAGC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_VPS72_ENST00000354473_chr1_151156793_-_ROBO2_ENST00000487694_chr3_77617464_+_4342nt AGGGGCTGCAGGTGGCGGCGCAGTCTCGGTAGGCGGTATGAGTTTGGCTGGGGGCCGGGCACCCCGGAAGACCGCTGGGAACCGGCTTTC TGGGCTTTTGGAGGCAGAGGAGGAAGATGAGTTCTACCAGACGACTTATGGGGGTTTCACAGAGGAATCCGGAGATGATGAGTATCAAGG GGACCAGTCAGACACAGAGGACGAAGTGGACTCTGACTTTGACATTGATGAAGGGGATGAACCATCCAGTGATGGAGAAGCAGAAGAGCC AAGAAGGAAGCGCCGAGTAGTCACCAAGGCCTATAAGGAACCTCTCAAGAGCTTAAGGCCTCGAAAGGTCAACACCCCGGCTGGTAGCTC TCAGAAGGCGCGAGAAGAGAAGGCACTACTGCCATTAGAACTACAAGATGACGGCTCTGACAGTCGGAAGTCTATGCGTCAGTCTACAGC TGAGCATACACGACAAACGTTCCTTCGGGTACAGGAGAGGCAGGGCCAGTCAAGACGGCGAAAGGGGCCCCACTGTGAGCGGCCACTAAC CCAGGAGGAACTGCTCCGGGAGGCCAAGATCACAGAAGAGCTTAATTTACGGTCACTGGATATCAGCCCACCAGCACAAGGAGTGGACCA CAGGCAAGTGCAGAAAGAGCTAGGAGATGTCCTTGTCCGTCTTCATAATCCAGTTGTGCTGACTCCCACCACGGTTCAGGTCACATGGAC GGTTGATCGCCAACCCCAGTTTATCCAAGGCTACCGAGTGATGTATCGTCAGACTTCAGGTCTGCAGGCGACATCTTCGTGGCAGAATTT AGATGCCAAAGTCCCGACTGAACGAAGTGCTGTCTTAGTCAACCTGAAAAAGGGGGTGACTTATGAAATTAAAGTACGGCCATATTTTAA TGAGTTCCAAGGAATGGATAGTGAATCTAAAACGGTTCGTACTACTGAAGAAGCCCCAAGTGCCCCACCACAGTCTGTCACTGTACTGAC AGTTGGAAGCTACAATAGCACAAGTATTAGTGTTTCCTGGGATCCTCCTCCTCCAGATCACCAGAATGGAATTATCCAAGAATACAAGAT CTGGTGTCTAGGAAATGAAACGCGATTCCATATCAACAAAACTGTGGATGCAGCCATTCGGTCCGTAATAATTGGTGGATTATTCCCAGG TATTCAATACCGGGTAGAGGTTGCAGCTAGTACCAGTGCAGGGGTTGGAGTAAAGAGTGAGCCACAGCCAATAATAATCGGGAGACGCAA TGAAGTTGTCATTACTGAAAACAATAACAGCATAACTGAGCAAATCACTGATGTGGTGAAGCAACCAGCCTTTATAGCTGGTATTGGTGG TGCCTGCTGGGTAATTCTGATGGGTTTTAGCATATGGTTGTATTGGCGAAGAAAGAAGAGGAAGGGACTCAGTAATTATGCTGTTACGTT TCAAAGAGGAGATGGAGGACTAATGAGCAATGGAAGCCGTCCAGGTCTTCTCAATGCTGGTGATCCCAGCTATCCATGGCTTGCTGATTC TTGGCCAGCCACGAGCTTGCCAGTAAATAATAGCAACAGTGGCCCAAATGAGATTGGAAATTTTGGCCGTGGAGATGTGCTGCCACCAGT TCCAGGCCAAGGGGATAAAACAGCAACGATGCTCTCAGATGGAGCCATTTATAGTAGCATTGACTTCACTACCAAAACCAGTTACAACAG TTCCAGCCAAATAACACAGGCTACCCCATATGCCACGACACAGATCTTGCATTCCAACAGCATACATGAATTGGCTGTCGATCTGCCTGA TCCACAATGGAAAAGCTCAATTCAGCAAAAAACAGATCTGATGGGATTTGGTTATTCTCTACCTGATCAGAACAAAGGTAACAATGGTGG GAAAGGTGGAAAAAAGAAGAAAAATAAAAACTCTTCTAAACCACAGAAAAACAATGGATCCACTTGGGCCAATGTCCCTCTACCTCCCCC CCCAGTCCAGCCCCTTCCTGGCACGGAGCTGGAACACTATGCAGTGGAACAACAAGAAAATGGCTATGACAGTGATAGCTGGTGCCCACC ATTGCCAGTACAAACTTACTTACACCAAGGTCTGGAAGATGAACTGGAAGAAGATGATGATAGGGTCCCAACACCTCCTGTTCGAGGCGT GGCTTCTTCTCCTGCTATCTCCTTTGGACAGCAGTCCACTGCAACTCTTACTCCATCCCCACGGGAAGAGATGCAACCCATGCTGCAGGC TCACCTGGATGAGTTGACAAGAGCCTATCAGTTTGATATAGCAAAACAAACATGGCACATTCAAAGCAATAATCAACCTCCACAGCCTCC AGTTCCACCGTTAGGTTATGTGTCTGGAGCCTTGATTTCTGATTTGGAAACGGATGTTGCAGATGATGATGCCGACGACGAAGAGGAAGC TTTAGAAATCCCCAGGCCCCTGAGAGCACTGGACCAGACTCCTGGATCCAGCATGGACAATCTAGACAGCTCTGTGACAGGAAAAGCCTT TACCTCCTCTCAAAGACCTCGACCTACCAGCCCATTTTCTACTGACAGTAACACCAGTGCAGCCCTGAGTCAAAGTCAGAGGCCTCGGCC CACTAAAAAACACAAGGGAGGGCGGATGGACCAACAACCAGCATTGCCTCATCGAAGGGAAGGAATGACAGATGAGGAGGCCTTGGTGCC CTATAGCAAGCCCAGTTTCCCATCTCCAGGTGGCCACAGCTCATCAGGAACAGCTTCTTCTAAGGGATCCACTGGACCTAGGAAAACCGA GGTGTTGAGAGCAGGCCACCAGCGCAATGCCAGCGACCTTCTTGACATAGGATATATGGGCTCCAACAGTCAAGGACAGTTTACAGGTGA ATTATAGTAAATGAGAGGAGACATACAAAGCTGCTCTGAAGGACCATCAGGTCCGGACTCATGGAAGTGATGACTCTAAACAGTGCAATG AACAATTTATTTATGTACTATTAAAAGAACTGTAAATGCAATGTAAAGACACACAGCCACACATATCCCACAGATATTTTCATTGTGTTC TTCTCTTAAGTACACCACCCACCTTAACTCTTTCTTGTCAGGAGTATATAAAAAAGAAAGAAAACAAAACTCGCCCTACAGGAAGAAAAG GATTCTCCTCTGTATATAATTTCTTTTGTGCATTGCTATGCAAGCTCACTCTTTTTAGCTCTGCTCATATTATTGTCTGTTCTTATTGGT CTGTTGTACTATATGTGAATTAATAGGCTGTGGTGCCATATATTAACTTTTAATTGTGTAACTTTTATGTTTAAATTTTGCACTGCAATT TTATTTGGTGATAAGCACAAATCTCTACTCCTCATGACATGAAGAAAAAGACTGAATGTGAAGGGAGTTTCTGTACTGTAAGCTAGATTG GATAATGATGGCTGTAACAAATCATGTTAGATGGTTTTCAGTTGGGGTGTAGAAATAGGAAGATGCAAAGGAACAATGGTGTTGGCAAAG TCTTCTTTGAATATCAGGGACTGAGTCAATAAAAAAAATAGTAGAAAGGTGGCTTTTACTATTGACAAAAGCCGGGGTCAAAAAAAGTAG TTTAAGTCTTAAGACTGAATATGCATTAAAGTATGCAGGTAGCAAAGATGTAATAAATTTGCTTAAAAAAAGAAATTAAAGTTTTATTTA GAATCAATTTTACCTGTCATTGTAATTGACCCATCTGAGAATTACAATAAGCAAGAGGAAATTAAGGTGTTTTGCAAGAGCTGTATTTAT ATTACAGTTTTTTAAAAACATTTTCTGAATTATCGTAATTAAGCTCTCCAACTCGTTAAGTCAGAATATAATATGAAGTTCCCCAAGGAA ACGAACAAAATGAACTCTAGAATATCTAGCAAATAGTTAAAGAAGCAATTTATTATTAGGGCATACTCGGGCTGTTTCCAAATATAAACT CTATTGCAATATCTTATTTCATCTTTCTAATACATGTACAGTGCACACTAGAGGATAGAGCTGCATCACTTAAATTCATGACTTAAAAAA TAATACAGTTTATATACAACTTGTTTTTTATTTGATTAAGAAGTGAAGTTTACGCCACCCAATGTATAGCCAAATTGTACGTGCTTAAAA AACAGTGCCGAGAGTATGTTCAGTTCGCAGTAAGTAGATTTATTGGAATAAATATTCTATGGTACATTCTCAGAAATTGGCTTCCAACTA AAATACGTTTGACCCATTTTGAATAAGGAAATTGAAAAGAAAAATTTAAAAGGAGAAAAAAATGCATGTTTATAAACTTTTTAAATAAAA >In-frame_VPS72_ENST00000354473_chr1_151156793_-_ROBO2_ENST00000461745_chr3_77617464_+_6796nt AGGGGCTGCAGGTGGCGGCGCAGTCTCGGTAGGCGGTATGAGTTTGGCTGGGGGCCGGGCACCCCGGAAGACCGCTGGGAACCGGCTTTC TGGGCTTTTGGAGGCAGAGGAGGAAGATGAGTTCTACCAGACGACTTATGGGGGTTTCACAGAGGAATCCGGAGATGATGAGTATCAAGG GGACCAGTCAGACACAGAGGACGAAGTGGACTCTGACTTTGACATTGATGAAGGGGATGAACCATCCAGTGATGGAGAAGCAGAAGAGCC AAGAAGGAAGCGCCGAGTAGTCACCAAGGCCTATAAGGAACCTCTCAAGAGCTTAAGGCCTCGAAAGGTCAACACCCCGGCTGGTAGCTC TCAGAAGGCGCGAGAAGAGAAGGCACTACTGCCATTAGAACTACAAGATGACGGCTCTGACAGTCGGAAGTCTATGCGTCAGTCTACAGC TGAGCATACACGACAAACGTTCCTTCGGGTACAGGAGAGGCAGGGCCAGTCAAGACGGCGAAAGGGGCCCCACTGTGAGCGGCCACTAAC CCAGGAGGAACTGCTCCGGGAGGCCAAGATCACAGAAGAGCTTAATTTACGGTCACTGGATATCAGCCCACCAGCACAAGGAGTGGACCA CAGGCAAGTGCAGAAAGAGCTAGGAGATGTCCTTGTCCGTCTTCATAATCCAGTTGTGCTGACTCCCACCACGGTTCAGGTCACATGGAC GGTTGATCGCCAACCCCAGTTTATCCAAGGCTACCGAGTGATGTATCGTCAGACTTCAGGTCTGCAGGCGACATCTTCGTGGCAGAATTT AGATGCCAAAGTCCCGACTGAACGAAGTGCTGTCTTAGTCAACCTGAAAAAGGGGGTGACTTATGAAATTAAAGTACGGCCATATTTTAA TGAGTTCCAAGGAATGGATAGTGAATCTAAAACGGTTCGTACTACTGAAGAAGCCCCAAGTGCCCCACCACAGTCTGTCACTGTACTGAC AGTTGGAAGCTACAATAGCACAAGTATTAGTGTTTCCTGGGATCCTCCTCCTCCAGATCACCAGAATGGAATTATCCAAGAATACAAGAT CTGGTGTCTAGGAAATGAAACGCGATTCCATATCAACAAAACTGTGGATGCAGCCATTCGGTCCGTAATAATTGGTGGATTATTCCCAGG TATTCAATACCGGGTAGAGGTTGCAGCTAGTACCAGTGCAGGGGTTGGAGTAAAGAGTGAGCCACAGCCAATAATAATCGGGAGACGCAA TGAAGTTGTCATTACTGAAAACAATAACAGCATAACTGAGCAAATCACTGATGTGGTGAAGCAACCAGCCTTTATAGCTGGTATTGGTGG TGCCTGCTGGGTAATTCTGATGGGTTTTAGCATATGGTTGTATTGGCGAAGAAAGAAGAGGAAGGGACTCAGTAATTATGCTGTTACGTT TCAAAGAGGAGATGGAGGACTAATGAGCAATGGAAGCCGTCCAGGTCTTCTCAATGCTGGTGATCCCAGCTATCCATGGCTTGCTGATTC TTGGCCAGCCACGAGCTTGCCAGTAAATAATAGCAACAGTGGCCCAAATGAGATTGGAAATTTTGGCCGTGGAGATGTGCTGCCACCAGT TCCAGGCCAAGGGGATAAAACAGCAACGATGCTCTCAGATGGAGCCATTTATAGTAGCATTGACTTCACTACCAAAACCAGTTACAACAG TTCCAGCCAAATAACACAGGCTACCCCATATGCCACGACACAGATCTTGCATTCCAACAGCATACATGAATTGGCTGTCGATCTGCCTGA TCCACAATGGAAAAGCTCAATTCAGCAAAAAACAGATCTGATGGGATTTGGTTATTCTCTACCTGATCAGAACAAAGGTAACAATGGTGG GAAAGGTGGAAAAAAGAAGAAAAATAAAAACTCTTCTAAACCACAGAAAAACAATGGATCCACTTGGGCCAATGTCCCTCTACCTCCCCC CCCAGTCCAGCCCCTTCCTGGCACGGAGCTGGAACACTATGCAGTGGAACAACAAGAAAATGGCTATGACAGTGATAGCTGGTGCCCACC ATTGCCAGTACAAACTTACTTACACCAAGGTCTGGAAGATGAACTGGAAGAAGATGATGATAGGGTCCCAACACCTCCTGTTCGAGGCGT GGCTTCTTCTCCTGCTATCTCCTTTGGACAGCAGTCCACTGCAACTCTTACTCCATCCCCACGGGAAGAGATGCAACCCATGCTGCAGGC TCACCTGGATGAGTTGACAAGAGCCTATCAGTTTGATATAGCAAAACAAACATGGCACATTCAAAGCAATAATCAACCTCCACAGCCTCC AGTTCCACCGTTAGGTTATGTGTCTGGAGCCTTGATTTCTGATTTGGAAACGGATGTTGCAGATGATGATGCCGACGACGAAGAGGAAGC TTTAGAAATCCCCAGGCCCCTGAGAGCACTGGACCAGACTCCTGGATCCAGCATGGACAATCTAGACAGCTCTGTGACAGGAAAAGCCTT TACCTCCTCTCAAAGACCTCGACCTACCAGCCCATTTTCTACTGACAGTAACACCAGTGCAGCCCTGAGTCAAAGTCAGAGGCCTCGGCC CACTAAAAAACACAAGGGAGGGCGGATGGACCAACAACCAGCATTGCCTCATCGAAGGGAAGGAATGACAGATGAGGAGGCCTTGGTGCC CTATAGCAAGCCCAGTTTCCCATCTCCAGGTGGCCACAGCTCATCAGGAACAGCTTCTTCTAAGGGATCCACTGGACCTAGGAAAACCGA GGTGTTGAGAGCAGGCCACCAGCGCAATGCCAGCGACCTTCTTGACATAGGATATATGGGCTCCAACAGTCAAGGACAGTTTACAGGTGA ATTATAGTAAATGAGAGGAGACATACAAAGCTGCTCTGAAGGACCATCAGGTCCGGACTCATGGAAGTGATGACTCTAAACAGTGCAATG AACAATTTATTTATGTACTATTAAAAGAACTGTAAATGCAATGTAAAGACACACAGCCACACATATCCCACAGATATTTTCATTGTGTTC TTCTCTTAAGTACACCACCCACCTTAACTCTTTCTTGTCAGGAGTATATAAAAAAGAAAGAAAACAAAACTCGCCCTACAGGAAGAAAAG GATTCTCCTCTGTATATAATTTCTTTTGTGCATTGCTATGCAAGCTCACTCTTTTTAGCTCTGCTCATATTATTGTCTGTTCTTATTGGT CTGTTGTACTATATGTGAATTAATAGGCTGTGGTGCCATATATTAACTTTTAATTGTGTAACTTTTATGTTTAAATTTTGCACTGCAATT TTATTTGGTGATAAGCACAAATCTCTACTCCTCATGACATGAAGAAAAAGACTGAATGTGAAGGGAGTTTCTGTACTGTAAGCTAGATTG GATAATGATGGCTGTAACAAATCATGTTAGATGGTTTTCAGTTGGGGTGTAGAAATAGGAAGATGCAAAGGAACAATGGTGTTGGCAAAG TCTTCTTTGAATATCAGGGACTGAGTCAATAAAAAAAATAGTAGAAAGGTGGCTTTTACTATTGACAAAAGCCGGGGTCAAAAAAAGTAG TTTAAGTCTTAAGACTGAATATGCATTAAAGTATGCAGGTAGCAAAGATGTAATAAATTTGCTTAAAAAAAGAAATTAAAGTTTTATTTA GAATCAATTTTACCTGTCATTGTAATTGACCCATCTGAGAATTACAATAAGCAAGAGGAAATTAAGGTGTTTTGCAAGAGCTGTATTTAT ATTACAGTTTTTTAAAAACATTTTCTGAATTATCGTAATTAAGCTCTCCAACTCGTTAAGTCAGAATATAATATGAAGTTCCCCAAGGAA ACGAACAAAATGAACTCTAGAATATCTAGCAAATAGTTAAAGAAGCAATTTATTATTAGGGCATACTCGGGCTGTTTCCAAATATAAACT CTATTGCAATATCTTATTTCATCTTTCTAATACATGTACAGTGCACACTAGAGGATAGAGCTGCATCACTTAAATTCATGACTTAAAAAA TAATACAGTTTATATACAACTTGTTTTTTATTTGATTAAGAAGTGAAGTTTACGCCACCCAATGTATAGCCAAATTGTACGTGCTTAAAA AACAGTGCCGAGAGTATGTTCAGTTCGCAGTAAGTAGATTTATTGGAATAAATATTCTATGGTACATTCTCAGAAATTGGCTTCCAACTA AAATACGTTTGACCCATTTTGAATAAGGAAATTGAAAAGAAAAATTTAAAAGGAGAAAAAAATGCATGTTTATAAACTTTTTAAATAAAA CCAGACCTTGTAAGTGGACATTAATAATTGTCCTGCCTCATTTGTTTTCACGACTTTGACAACAAGAAGTTCCTGAACATTAGTCATGTA TGCTCAGAATAAATGTGACTTTGAAATATATGTTAGCTACTGTACATGTATAGTCAGTCAAGTAGAAGAGGACCTTCCTGAAATTCCCAC TTGTGACATTTTCCCATGGGTTTCCTACACAATCTTAAATTTTATTTCTGTCTATACTTTCTCAAATTTTTCCTATGATAAGTTCAGTTG TTGGTACTCTTCTAAAAATATTCAACGTGATTAGGATCAGTTCTAAAATACGGGACCCCTTTGAGTGACAATTCGCACTCCATGCATTAT TGGCTCAGTAGCCAATTTTTGTCACGTCGTTATAACAAGGAGATGACATAATTAAACATTTCCATCCTTTCTATTCCCTGAGACTGCATC AGCACAGGCAAGTATAGAATGTAATGTTCTTCATGGGCCCCACCAGCTTTTTGGTGCCATGTAATTTATTTCTTCGCTGAAGAGAAAAAG AATTCTGAGACACAGTTATTAAACCCTTTATCAACTTTCTACCATCAGTGCCTGAATTCTAATGCAGTGTGATTTCTCTGGGACAAAGAG ACTGAGGAAGATGAAAAGTTTCTTCAAAGAGTGAATACATACTTATTCACAACTCTAGGATGTGAGGACTTTAAATATCTCTTTATGAAG TTCCCTGCCTAACCTCTTTCTATTTAAAGGCAAACAAATTTCGAAGAGGTTTTGTGTTCCCTCTTTATGTTTCTCTATGACCCAGTTTAG TCTAAAACCTTAGTTCATTACATATACAACACATAGCCTTTGATCCCTGGTAACTGGCAGGTGTTGGTGATTAATAAACCAAGGCTTCAA AGTGAAGTATGTGTGTGCAGATGACTTTTGGAATAACGTGGGCATAGCATCATACCTTCCTGATTGTCTTCAGCATATAAAAATTAACTG TTGTAGTTAAAATTATGTCAGTGCAGAGCTTGTGGTTACTTGGAATGTTCTTTCAGAATAGTCCATGTTGCCTATTAAACCTAGTTTTAA ACACATTGGGCAGTCAATTTATGCACCCAAAATATCACCCTCAGGTAGATTGAGGGCAAGATAAAATGCTGTATGTAGCTATACAAAGGA ATTCAGAAACATTACTGGAAAGCAAAGCCTTTGTCAGCTTGCTACTGACAAAGTAGTAAAAAGCTACTAATCAGTGTTGAGTCAGATGTC AACAGAAAAATACAAATACCTATGAGAGCCACAGCAGTTTCTCGTTTCATAGCCGATTCAATGAATATGATTAGAAATTCACTGAGCTCA CTCTTGCAGGTTTAAATGGAGGCCTGCATAAGGACTGCAAGAGGAAATCTGGGTGGGAGAGAATGTAATCTGATCTTGCACTCATAGGCA ATGCTGCAATGCAATCATGTCCAATACAAGCACAGCTTCATTCATAACAGGAAACGTCTTCTTTGGGAAAATAGCTCTATTGGTGCCCAA ACTCAGGTATGCCAGTGTATGCAGGTGGAGTCGCCCTACCCCTCTTCCAAACATGTCCTGTGAGATTTTTAAAATAAGATGGGATAGTAC AGGGGCATGAAAAGAATTGATTCCTTCACAGGATTTGAATCCAGTTCAAGGGAGAATGTAGAAAATTCAAAACCAACATATAAGGTATCA CACAACCAAGAAAAGTAAAACCATTGCAAGTTTACTTGCGTTGAGTACAAAACAGATTTAATGGTGTTCTATGTCATAGTTTAATGCTCT GGGTATTTAAATATGTTTTCAACAGGATTTGAGTTGAAAGTTTGTAATGTGCTTTGATGGAACACCTCTCAATTTCTATTCAATAAACTT ATGTAATTGTCCATTGACAATATAATGATAACAGTACCATTGAACTCTAAACTGTGGTTTATCTTCACTACTGGGAAGCAACTGTGCATC AGTATTAAAGATATGCAGAAACATAATATTCACTAATTTGTTCATCTGCTTCTGTATATTGTTTATGGAATTACATGGCAAGAACTGTTC TAAAGCAACATGTCTTTCCACATTATTTTAGAGGTGAAATTACTTTTGTTTTGCTTCTCTATAATGTGTACTTCAAATGAAACACCATAC TTTTTTCTAAAAAAAGATGTTCAATTTACTAATTTTTTTAAATCTCATAATTTAAAAAGCATTTGTTGTGATTTTAAAGTGTTGCAAGAA AAGGGATTTTGTGGCCGTGGGTAGACTTTTTATACTTTGTTTTATAGATGGATTTTTTTTAACTGTAGTTTGTTTAAGTCACCAAGCAGC ATCCAAAATCTTAATGTGTTTCATTTGATGTTGTTAGATCAGAGAAGAAATTGGCATAAAATCGGTTAATAGTATTGTCAAAGAATTGTG >In-frame_VPS72_ENST00000354473_chr1_151156793_-_ROBO2_ENST00000332191_chr3_77617464_+_4131nt AGGGGCTGCAGGTGGCGGCGCAGTCTCGGTAGGCGGTATGAGTTTGGCTGGGGGCCGGGCACCCCGGAAGACCGCTGGGAACCGGCTTTC TGGGCTTTTGGAGGCAGAGGAGGAAGATGAGTTCTACCAGACGACTTATGGGGGTTTCACAGAGGAATCCGGAGATGATGAGTATCAAGG GGACCAGTCAGACACAGAGGACGAAGTGGACTCTGACTTTGACATTGATGAAGGGGATGAACCATCCAGTGATGGAGAAGCAGAAGAGCC AAGAAGGAAGCGCCGAGTAGTCACCAAGGCCTATAAGGAACCTCTCAAGAGCTTAAGGCCTCGAAAGGTCAACACCCCGGCTGGTAGCTC TCAGAAGGCGCGAGAAGAGAAGGCACTACTGCCATTAGAACTACAAGATGACGGCTCTGACAGTCGGAAGTCTATGCGTCAGTCTACAGC TGAGCATACACGACAAACGTTCCTTCGGGTACAGGAGAGGCAGGGCCAGTCAAGACGGCGAAAGGGGCCCCACTGTGAGCGGCCACTAAC CCAGGAGGAACTGCTCCGGGAGGCCAAGATCACAGAAGAGCTTAATTTACGGTCACTGGATATCAGCCCACCAGCACAAGGAGTGGACCA CAGGCAAGTGCAGAAAGAGCTAGGAGATGTCCTTGTCCGTCTTCATAATCCAGTTGTGCTGACTCCCACCACGGTTCAGGTCACATGGAC GGTTGATCGCCAACCCCAGTTTATCCAAGGCTACCGAGTGATGTATCGTCAGACTTCAGGTCTGCAGGCGACATCTTCGTGGCAGAATTT AGATGCCAAAGTCCCGACTGAACGAAGTGCTGTCTTAGTCAACCTGAAAAAGGGGGTGACTTATGAAATTAAAGTACGGCCATATTTTAA TGAGTTCCAAGGAATGGATAGTGAATCTAAAACGGTTCGTACTACTGAAGAAGCCCCAAGTGCCCCACCACAGTCTGTCACTGTACTGAC AGTTGGAAGCTACAATAGCACAAGTATTAGTGTTTCCTGGGATCCTCCTCCTCCAGATCACCAGAATGGAATTATCCAAGAATACAAGAT CTGGTGTCTAGGAAATGAAACGCGATTCCATATCAACAAAACTGTGGATGCAGCCATTCGGTCCGTAATAATTGGTGGATTATTCCCAGG TATTCAATACCGGGTAGAGGTTGCAGCTAGTACCAGTGCAGGGGTTGGAGTAAAGAGTGAGCCACAGCCAATAATAATCGGGAGACGCAA TGAAGTTGTCATTACTGAAAACAATAACAGCATAACTGAGCAAATCACTGATGTGGTGAAGCAACCAGCCTTTATAGCTGGTATTGGTGG TGCCTGCTGGGTAATTCTGATGGGTTTTAGCATATGGTTGTATTGGCGAAGAAAGAAGAGGAAGGGACTCAGTAATTATGCTGTTACGTT TCAAAGAGGAGATGGAGGACTAATGAGCAATGGAAGCCGTCCAGGTCTTCTCAATGCTGGTGATCCCAGCTATCCATGGCTTGCTGATTC TTGGCCAGCCACGAGCTTGCCAGTAAATAATAGCAACAGTGGCCCAAATGAGATTGGAAATTTTGGCCGTGGAGATGTGCTGCCACCAGT TCCAGGCCAAGGGGATAAAACAGCAACGATGCTCTCAGATGGAGCCATTTATAGTAGCATTGACTTCACTACCAAAACCAGTTACAACAG TTCCAGCCAAATAACACAGGCTACCCCATATGCCACGACACAGATCTTGCATTCCAACAGCATACATGAATTGGCTGTCGATCTGCCTGA TCCACAATGGAAAAGCTCAATTCAGCAAAAAACAGATCTGATGGGATTTGGTTATTCTCTACCTGATCAGAACAAAGGTAACAATGGTGG GAAAGGTGGAAAAAAGAAGAAAAATAAAAACTCTTCTAAACCACAGAAAAACAATGGATCCACTTGGGCCAATGTCCCTCTACCTCCCCC CCCAGTCCAGCCCCTTCCTGGCACGGAGCTGGAACACTATGCAGTGGAACAACAAGAAAATGGCTATGACAGTGATAGCTGGTGCCCACC ATTGCCAGTACAAACTTACTTACACCAAGGTCTGGAAGATGAACTGGAAGAAGATGATGATAGGGTCCCAACACCTCCTGTTCGAGGCGT GGCTTCTTCTCCTGCTATCTCCTTTGGACAGCAGTCCACTGCAACTCTTACTCCATCCCCACGGGAAGAGATGCAACCCATGCTGCAGGC TCACCTGGATGAGTTGACAAGAGCCTATCAGTTTGATATAGCAAAACAAACATGGCACATTCAAAGCAATAATCAACCTCCACAGCCTCC AGTTCCACCGTTAGGTTATGTGTCTGGAGCCTTGATTTCTGATTTGGAAACGGATGTTGCAGATGATGATGCCGACGACGAAGAGGAAGC TTTAGAAATCCCCAGGCCCCTGAGAGCACTGGACCAGACTCCTGGATCCAGCATGGACAATCTAGACAGCTCTGTGACAGGTTCAATGGT AAATGGATGGGGCTCTGCATCTGATGAGGATCGTAACTTTTCTAGTCATAGATCTAGTGTAGGTAGCTCCTCAGATGGCTCTATCTTTGC CAGCGGCAGTTTTGCACAAGCACTGGTGGCAGCAGCAGATAAAGCTGGTTTTAGGCTGGATGGAACCAGCCTTACAAGAACAGGAAAAGC CTTTACCTCCTCTCAAAGACCTCGACCTACCAGCCCATTTTCTACTGACAGTAACACCAGTGCAGCCCTGAGTCAAAGTCAGAGGCCTCG GCCCACTAAAAAACACAAGGGAGGGCGGATGGACCAACAACCAGCATTGCCTCATCGAAGGGAAGGAATGACAGATGAGGAGGCCTTGGT GCCCTATAGCAAGCCCAGTTTCCCATCTCCAGGTGGCCACAGCTCATCAGGAACAGCTTCTTCTAAGGGATCCACTGGACCTAGGAAAAC CGAGGTGTTGAGAGCAGGCCACCAGCGCAATGCCAGCGACCTTCTTGACATAGGATATATGGGCTCCAACAGTCAAGGACAGTTTACAGG TGAATTATAGTAAATGAGAGGAGACATACAAAGCTGCTCTGAAGGACCATCAGGTCCGGACTCATGGAAGTGATGACTCTAAACAGTGCA ATGAACAATTTATTTATGTACTATTAAAAGAACTGTAAATGCAATGTAAAGACACACAGCCACACATATCCCACAGATATTTTCATTGTG TTCTTCTCTTAAGTACACCACCCACCTTAACTCTTTCTTGTCAGGAGTATATAAAAAAGAAAGAAAACAAAACTCGCCCTACAGGAAGAA AAGGATTCTCCTCTGTATATAATTTCTTTTGTGCATTGCTATGCAAGCTCACTCTTTTTAGCTCTGCTCATATTATTGTCTGTTCTTATT GGTCTGTTGTACTATATGTGAATTAATAGGCTGTGGTGCCATATATTAACTTTTAATTGTGTAACTTTTATGTTTAAATTTTGCACTGCA ATTTTATTTGGTGATAAGCACAAATCTCTACTCCTCATGACATGAAGAAAAAGACTGAATGTGAAGGGAGTTTCTGTACTGTAAGCTAGA TTGGATAATGATGGCTGTAACAAATCATGTTAGATGGTTTTCAGTTGGGGTGTAGAAATAGGAAGATGCAAAGGAACAATGGTGTTGGCA AAGTCTTCTTTGAATATCAGGGACTGAGTCAATAAAAAAAATAGTAGAAAGGTGGCTTTTACTATTGACAAAAGCCGGGGTCAAAAAAAG TAGTTTAAGTCTTAAGACTGAATATGCATTAAAGTATGCAGGTAGCAAAGATGTAATAAATTTGCTTAAAAAAAGAAATTAAAGTTTTAT TTAGAATCAATTTTACCTGTCATTGTAATTGACCCATCTGAGAATTACAATAAGCAAGAGGAAATTAAGGTGTTTTGCAAGAGCTGTATT TATATTACAGTTTTTTAAAAACATTTTCTGAATTATCGTAATTAAGCTCTCCAACTCGTTAAGTCAGAATATAATATGAAGTTCCCCAAG |
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FusionGenePPI for VPS72_ROBO2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| VPS72 | CALCOCO2, EWSR1, CCDC85B, MDFI, MRGBP, DMAP1, KAT5, CEBPA, ELAVL1, H2AFZ, SRCAP, RUVBL1, RUVBL2, ZFC3H1, PRMT1, HMBOX1, MAGEA10, PLAC1, FOXR1, QPRT, FOXR2, MORF4L1, CARD8, HIST1H2BA, YEATS4, ANP32A, ANP32B, ANP32E, SET, STK11, HIST1H2BG, KPNA1, TRRAP, ING3, EPC1, MBTD1, MYCL, MORF4L2, P4HA3, MEAF6, NFATC2IP, ZNHIT1, TRIM25 | ROBO2 | CPE, BNIP3L, RDH11, CENPU, RPS6KA5, HLA-DPB1, TRIM13, NR1H2, NR4A1, UBQLN4, MYC, MYCBP2, KIF2A, VAPA, KIF1C, TMEM248, METTL3, PARD6B |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for VPS72_ROBO2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for VPS72_ROBO2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ROBO2 | C0004352 | Autistic Disorder | 1 | CTD_human |
| Tgene | ROBO2 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Tgene | ROBO2 | C0023897 | Liver Diseases, Parasitic | 1 | CTD_human |
| Tgene | ROBO2 | C0206698 | Cholangiocarcinoma | 1 | CTD_human |
| Tgene | ROBO2 | C1970483 | Vesicoureteral Reflux 2 | 1 | CTD_human;UNIPROT |
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