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Fusion gene ID: 41629 |
FusionGeneSummary for VPS53_RTN4RL1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: VPS53_RTN4RL1 | Fusion gene ID: 41629 | Hgene | Tgene | Gene symbol | VPS53 | RTN4RL1 | Gene ID | 55275 | 146760 |
| Gene name | VPS53, GARP complex subunit | reticulon 4 receptor like 1 | |
| Synonyms | HCCS1|PCH2E|hVps53L|pp13624 | NGRH2|NgR3 | |
| Cytomap | 17p13.3 | 17p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | vacuolar protein sorting-associated protein 53 homolog | reticulon-4 receptor-like 1Nogo-66 receptor homolog 2Nogo-66 receptor-related protein 3nogo receptor-like 2 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q5VIR6 | Q86UN2 | |
| Ensembl transtripts involved in fusion gene | ENST00000437048, ENST00000574029, ENST00000576149, ENST00000446250, ENST00000291074, ENST00000571805, ENST00000401468, | ENST00000331238, | |
| Fusion gene scores | * DoF score | 10 X 5 X 10=500 | 6 X 1 X 7=42 |
| # samples | 13 | 7 | |
| ** MAII score | log2(13/500*10)=-1.94341647163363 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/42*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: VPS53 [Title/Abstract] AND RTN4RL1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-OL-A5RW-01A | VPS53 | chr17 | 600658 | - | RTN4RL1 | chr17 | 1841102 | - |
| TCGA | LD | OV | TCGA-29-1702-01A | VPS53 | chr17 | 505035 | - | RTN4RL1 | chr17 | 1841102 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000437048 | ENST00000331238 | VPS53 | chr17 | 600658 | - | RTN4RL1 | chr17 | 1841102 | - |
| intron-3CDS | ENST00000574029 | ENST00000331238 | VPS53 | chr17 | 600658 | - | RTN4RL1 | chr17 | 1841102 | - |
| intron-3CDS | ENST00000576149 | ENST00000331238 | VPS53 | chr17 | 600658 | - | RTN4RL1 | chr17 | 1841102 | - |
| 5UTR-3CDS | ENST00000446250 | ENST00000331238 | VPS53 | chr17 | 600658 | - | RTN4RL1 | chr17 | 1841102 | - |
| Frame-shift | ENST00000291074 | ENST00000331238 | VPS53 | chr17 | 600658 | - | RTN4RL1 | chr17 | 1841102 | - |
| Frame-shift | ENST00000571805 | ENST00000331238 | VPS53 | chr17 | 600658 | - | RTN4RL1 | chr17 | 1841102 | - |
| Frame-shift | ENST00000401468 | ENST00000331238 | VPS53 | chr17 | 600658 | - | RTN4RL1 | chr17 | 1841102 | - |
| Frame-shift | ENST00000437048 | ENST00000331238 | VPS53 | chr17 | 505035 | - | RTN4RL1 | chr17 | 1841102 | - |
| intron-3CDS | ENST00000574029 | ENST00000331238 | VPS53 | chr17 | 505035 | - | RTN4RL1 | chr17 | 1841102 | - |
| 5UTR-3CDS | ENST00000576149 | ENST00000331238 | VPS53 | chr17 | 505035 | - | RTN4RL1 | chr17 | 1841102 | - |
| In-frame | ENST00000446250 | ENST00000331238 | VPS53 | chr17 | 505035 | - | RTN4RL1 | chr17 | 1841102 | - |
| Frame-shift | ENST00000291074 | ENST00000331238 | VPS53 | chr17 | 505035 | - | RTN4RL1 | chr17 | 1841102 | - |
| Frame-shift | ENST00000571805 | ENST00000331238 | VPS53 | chr17 | 505035 | - | RTN4RL1 | chr17 | 1841102 | - |
| Frame-shift | ENST00000401468 | ENST00000331238 | VPS53 | chr17 | 505035 | - | RTN4RL1 | chr17 | 1841102 | - |
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FusionProtFeatures for VPS53_RTN4RL1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| VPS53 | RTN4RL1 |
| Acts as component of the GARP complex that is involvedin retrograde transport from early and late endosomes to thetrans-Golgi network (TGN). The GARP complex is required for themaintenance of the cycling of mannose 6-phosphate receptorsbetween the TGN and endosomes, this cycling is necessary forproper lysosomal sorting of acid hydrolases such as CTSD(PubMed:15878329, PubMed:18367545). Acts as component of the EARPcomplex that is involved in endocytic recycling. The EARP complexassociates with Rab4-positive endosomes and promotes recycling ofinternalized transferrin receptor (TFRC) to the plasma membrane(PubMed:25799061). {ECO:0000269|PubMed:15878329,ECO:0000269|PubMed:18367545, ECO:0000269|PubMed:25799061}. | Cell surface receptor. Plays a functionally redundantrole in postnatal brain development and in regulating axonregeneration in the adult central nervous system. Contributes tonormal axon migration across the brain midline and normalformation of the corpus callosum. Protects motoneurons againstapoptosis; protection against apoptosis is probably mediated byMAG. Plays a role in inhibiting neurite outgrowth and axonregeneration via its binding to neuronal chondroitin sulfateproteoglycans. Binds heparin (By similarity). Like other familymembers, plays a role in restricting the number dendritic spinesand the number of synapses that are formed during braindevelopment (PubMed:22325200). Signaling mediates activation ofRho and downstream reorganization of the actin cytoskeleton(PubMed:22325200). {ECO:0000250|UniProtKB:Q8K0S5,ECO:0000269|PubMed:22325200}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for VPS53_RTN4RL1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_VPS53_ENST00000446250_chr17_505035_-_RTN4RL1_ENST00000331238_chr17_1841102_-_437aa GAVWSCCCCWXLRSCPWVVAAHGTVCATRRPXRSAARRTTLQPSRRASPWTASASSCRTTASASSSPATSAPPWSPCGSTRTTSPTSTPA PSRASCTWRSWTSATTGSCGRWHPRPSRAWXSFTPSTSTSVGSAPCRPASLAACTACSTSTCRTTTSSTSRTTSSWTWSTSATCFSTATS CGVWARAPSGAWXTWTVFCCTRTSCSGSTTRRSTTSAGXPPSSSSTTASRSCRVSAWPRWGPWSSSASTATPGTVVVARAPCGNGCRGSG APAPLSPVCPLGCGTARTXSCXGPRTSGTARDQRPRTRSSHTRSPPPTGPPARNTTHPTAPPGARATRTAPGPATGSRGRTAPTPGTAIR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_VPS53_ENST00000446250_chr17_505035_-_RTN4RL1_ENST00000331238_chr17_1841102_-_1313nt GGTGCTGTGTGGAGTTGCTGCTGCTGTTGGTAGCTGCGGAGCTGCCCCTGGGTGGTGGCTGCCCACGGGACTGTGTGTGCTACCCGGCGC CCATGACGGTCAGCTGCCAGGCGCACAACTTTGCAGCCATCCCGGAGGGCATCCCCGTGGACAGCGAGCGCGTCTTCCTGCAGAACAACC GCATCGGCCTCCTCCAGCCCGGCCACTTCAGCCCCGCCATGGTCACCCTGTGGATCTACTCGAACAACATCACCTACATCCACCCCAGCA CCTTCGAGGGCTTCGTGCACCTGGAGGAGCTGGACCTCGGCGACAACCGGCAGCTGCGGACGCTGGCACCCGAGACCTTCCAGGGCCTGG TGAAGCTTCACGCCCTCTACCTCTACAAGTGTGGGCTCAGCGCCTTGCCGGCCGGCGTCTTTGGCGGCCTGCACAGCCTGCAGTACCTCT ACCTGCAGGACAACCACATCGAGTACCTCCAGGACGACATCTTCGTGGACCTGGTCAACCTCAGCCACCTGTTTCTCCACGGCAACAAGC TGTGGAGTCTGGGCCCGGGCACCTTCCGGGGCCTGGTGAACCTGGACCGTCTTTTGCTGCACGAGAACCAGCTGCAGTGGGTCCACCACA AGGCGTTCCACGACCTCCGCAGGCTGACCACCCTCTTCCTCTTCAACAACAGCCTCTCGGAGCTGCAGGGTGAGTGCCTGGCCCCGCTGG GGGCCCTGGAGTTCCTCCGCCTCAACGGCAACCCCTGGGACTGTGGTTGTCGCGCGCGCTCCCTGTGGGAATGGCTGCAGAGGTTCCGGG GCTCCAGCTCCGCTGTCCCCTGTGTGTCCCCTGGGCTGCGGCACGGCCAGGACCTGAAGCTGCTGAGGGCCGAGGACTTCCGGAACTGCA CGGGACCAGCGTCCCCGCACCAGATCAAGTCACACACGCTCACCACCACCGACAGGGCCGCCCGCAAGGAACACCACTCACCCCACGGCC CCACCAGGAGCAAGGGCCACCCGCACGGCCCCCGGCCCGGCCACAGGAAGCCGGGGAAGAACTGCACCAACCCCAGGAACCGCAATCAGA TCTCTAAGGCGGGCGCCGGGAAACAGGCCCCCGAGCTGCCAGACTATGCCCCAGACTACCAGCACAAGTTCAGTTTTGACATCATGCCTA CGGCCCGGCCCAAGAGGAAGGGCAAGTGTGCCCGCAGGACCCCCATCCGTGCCCCCAGCGGGGTGCAGCAGGCCTCCTCGGCCAGTTCCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_VPS53_ENST00000446250_chr17_505035_-_RTN4RL1_ENST00000331238_chr17_1841102_-_4595nt GAAGTGCCGGAGCGGCTGACAGAGCGGCTGACGGAGCCGGGCTCACCAGGTCGCTGCCGCGAGGGAGTTGCTGTGCTGGGGCCTGGGTGG CGGCTGGAGGCCTGAGTTGGGCTCGCGGCGGGGGTCGGCAGGGGGCCGGGTGGCGGAATGATGGAGGAGGAGGAACTGGAGTTCGTGGAG GAGCTGGAAGCCGTGCTGCAGCTCACGCCCGAGGTGCAGCTGGCCATCGAGCAGGTGTTTCCAAGCCAGGACCCTCTAGATCGAGCAGAT TTCAATGCTGTTGAGTATATCAATACCCTGTTCCCAACCGAGCAATCTCTGGCGAACATAGACGAAGTCGTGAACAAAATTAGGCTGAAA ATAAGGAGACTGGATGACAATATTCGAACTGTTGTAAGAGGTCAGACGAACGTGGGGCAGGATGGACGGCAAGCGCTTGAAGAGGCTCAG AAAGCTATCCAACAACTCTTTGGCAAAATCAAAGATATCAAAGACAAAGCTGAAAAATCAGAGCAAATGGTGAAAGAAATCACCCGTGAT ATTAAGCAATTAGATCACGCCAAACGCCACCTGACCACCTCAATCACCACACTGAACCACCTGCACATGCTGGCAGGAGGTGTCGACTCC CTCGAAGCCATGACCAGGCGAAGACAATACGGAGAAGTTGCTAATCTCCTTCAGGGTGTGATGAATGTCCTGGAGCACTTCCACAAGTAT ATGGGGATTCCGCAGATCCGGCAGCTTTCCGAAAGGAAACCCAAAACACTGCAGCTGCATGGATTGAACTGGACGTGATGTGAAATGAAA TAAGCCAGACACGGGAAGACAGATTCCTCATGTTCTCACTCATAGTGAAGGCTGCACAGACTGAGTTAGGACAGCAAATCCTGGCAGATT TTGAAGAAGCGTTTCCTTCCCAGGGCACCAAGAGACCAGGAGGACCCAGCAATGTTCTACGAGATGCATGTCTGGTTGCTAATATTCTAG ATCCCAGGATCAAACAGGAAATCATCAAAAAGTTTATTAAACAGCATCTGTCAGAGTATCTGGTACTTTTTCAAGAAAACCAAGATGTTG CCTGGCTGGACAAAATCGACAGACGCTATGCCTGGATAAAACGCCAGCTTGTGGACTATGAGGAGAAATACGGCCGCATGTTTCCACGTG AGTGGTGCATGGCTGAGAGGATTGCGGTGGAATTTTGCCATGTGACAAGGGCAGAACTTGCCAAGATTATGCGTACCAGAGCGAAGGAAA TTGAAGTGAAATTGCTTCTTTTTGCTATTCAAAGAACAACTAACTTTGAGGGGTTTCTTGCAAAACGCTTCTCCGGCTGCACCCTGACCG ATGGGACCCTGAAAAAGCTTGAGTCTCCACCCCCATCTACCAATCCCTTCCTGGAAGATGAGCCAACACCAGAGATGGAGGAACTGGCAA CGGAGAAAGGAGATTTAGATCAAGGTGCTGTGTGGAGTTGCTGCTGCTGTTGGTAGCTGCGGAGCTGCCCCTGGGTGGTGGCTGCCCACG GGACTGTGTGTGCTACCCGGCGCCCATGACGGTCAGCTGCCAGGCGCACAACTTTGCAGCCATCCCGGAGGGCATCCCCGTGGACAGCGA GCGCGTCTTCCTGCAGAACAACCGCATCGGCCTCCTCCAGCCCGGCCACTTCAGCCCCGCCATGGTCACCCTGTGGATCTACTCGAACAA CATCACCTACATCCACCCCAGCACCTTCGAGGGCTTCGTGCACCTGGAGGAGCTGGACCTCGGCGACAACCGGCAGCTGCGGACGCTGGC ACCCGAGACCTTCCAGGGCCTGGTGAAGCTTCACGCCCTCTACCTCTACAAGTGTGGGCTCAGCGCCTTGCCGGCCGGCGTCTTTGGCGG CCTGCACAGCCTGCAGTACCTCTACCTGCAGGACAACCACATCGAGTACCTCCAGGACGACATCTTCGTGGACCTGGTCAACCTCAGCCA CCTGTTTCTCCACGGCAACAAGCTGTGGAGTCTGGGCCCGGGCACCTTCCGGGGCCTGGTGAACCTGGACCGTCTTTTGCTGCACGAGAA CCAGCTGCAGTGGGTCCACCACAAGGCGTTCCACGACCTCCGCAGGCTGACCACCCTCTTCCTCTTCAACAACAGCCTCTCGGAGCTGCA GGGTGAGTGCCTGGCCCCGCTGGGGGCCCTGGAGTTCCTCCGCCTCAACGGCAACCCCTGGGACTGTGGTTGTCGCGCGCGCTCCCTGTG GGAATGGCTGCAGAGGTTCCGGGGCTCCAGCTCCGCTGTCCCCTGTGTGTCCCCTGGGCTGCGGCACGGCCAGGACCTGAAGCTGCTGAG GGCCGAGGACTTCCGGAACTGCACGGGACCAGCGTCCCCGCACCAGATCAAGTCACACACGCTCACCACCACCGACAGGGCCGCCCGCAA GGAACACCACTCACCCCACGGCCCCACCAGGAGCAAGGGCCACCCGCACGGCCCCCGGCCCGGCCACAGGAAGCCGGGGAAGAACTGCAC CAACCCCAGGAACCGCAATCAGATCTCTAAGGCGGGCGCCGGGAAACAGGCCCCCGAGCTGCCAGACTATGCCCCAGACTACCAGCACAA GTTCAGTTTTGACATCATGCCTACGGCCCGGCCCAAGAGGAAGGGCAAGTGTGCCCGCAGGACCCCCATCCGTGCCCCCAGCGGGGTGCA GCAGGCCTCCTCGGCCAGTTCCCTGGGGGCCTCCCTCCTGGCCTGGACACTGGGGCTGGCGGTCACTCTCCGCTGAGGACCCAGGGCGTC AGCACCCAGCACTGCCACATGTCCACCAAGGAACAGAATTTATTTTCTTCTTTTTTTAACAAGTGGAAGATCTGCTGGGTTTCAGGAAAA GGCTGGTAGAGCCTTCGGCTGCTGTCTGGACGTCTGGACCCTGCCATGTGGATTATAAACCCAAAGTGTACAGCCCTAGGCGGGAGGGGG TGGCGCTTCTCAGCCGGCTGTCCCAGCCAGCCCCGCAGAGCGCCCACGGACAGTGTCCACTCTGGCAAGGTGGGAAAAGGCACTCCAAGT GCATCCTCCACTGGCAACAGTGGGACAATTGCCCCCGACGGCGGCACCGGGGCTCTGTGGAATCCCGATCGTTCCGAGAGGTCTGGAGGG CCCCGTGGTTCCTGGAGAAAGCAGGACGCAGAGAAGAACAAATGAGGCTCACCCACGAGGCTGGGTGGCCAGCAGTCTGGGCACACACGA GCAGGTGGCATCTTGGCTCTTGCCTGAGGCCAGTCACCCTGCCCTGAATTCTATCCTACTCCACCTTCAGCCCCTCCCTCGGGGGTAGCG CCTCTCATTCCTGATGTCTCAGGCAACCCTGGCAGACCCAGGTCCAACTGCTGGGGTCCAAGAACCAATTACCAAAGGAAAGATCATCAG AGGCTGAAATCTAGAACTTCATCCCGGGCAATGAGGTTCTCACAGAAGGTGCAGTTTTATAACTAACTACGTCCACTTATATATATTCAC ACTCTACATATATATATATATATATATATATATATATATATATATATATACACAAATGCACAGTCCCCCTCCCACTCCGTTACCTAACTG TACGTCTTTTCATGTTTATAAACTATACAGAAAACTGTATTTGCTGAACTAAGGATTGTATTGGTGATTTCTAGCAAAAACAAAGTGATA GAATTTTTGTCTAGAATCCCAAACTGGCAACGATAGTCTCCAAGGGACCTGGCCTTGCCAAGGGCCTGGGGCAAGGTGTCGGCGGGACGG TGAGGAAGGGGGAGGCAGCAAGAGTCACTTTGGGGGACCAATATTCTTAGATATTTAGAGCATCACCTTGTTTTTATATGCAACACAAGC CTGTCTGCCACCCTGGAGCGCCCTGTCACCCCTGCTGTCGTAGCTGTTGGCTTCAGGGTGAGAAGTGAGAAGCAGCTTATTGTATATGAG GGAGCCAGGCCCCGAGGGTGAGCGAGATGGAGAAGGGGAAGGAAGGGGCTTTGGGATCTGGAAACCAGCAGGCCAGGCAGCATCCACAGT GTTAGTCCAAAGGGTCGGACCGTGTCGTCAGCCTAGCGTTTGGTCAGTGACGGCCTGGACGGGCCAAGGAGACTCCGGGCTTGAGCCCAG GCCTCCCGCACGGCTCAGCTGCTGAATTTTTCCTTGAGGCTGTTTGGTGTGTGACCCAGCAAGGGCCCTGTGTGGGACAGCAGGAGGGAG GCGTCGGGGGCCTTAGCAGAAGGGGAACAATGAGGGCATTTCATGAACCATCTCAGGCACTTCTGCATCACGGAAGACCTGGCCCTCCCA GCCGTCCTGGGGATGCTCAGGGTGCAGGCAGAGGCTCGGGAGGCCGGACTCAGGGGTCAGAAGCAGGGACTGGGGCAGGCGAGCCCGGAC AGGGAAGAGGGGCTCCGATCAAAGCCGGCCGTGCTGCTGGCCGGGGGCCCAGGTGGGTACAAGCTCCTTTGTGCTTTGCACAAACCTGAA TCCCCCACCAGAGAGGATGTGTGTGAGGAGCCAGAAACGCTGAATCCAATTAAGAGAGAAAAATAATAATAACAATAAATGATCTTGGAC |
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FusionGenePPI for VPS53_RTN4RL1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| VPS53 | VPS52, VPS51, EXOC2, VPS53, VPS54, STX6, VAMP4, THOC2, THOC1, USP7, TXNDC9, VCP, SNAP29, BSG, PSMD7, CCDC132, DTNBP1, TSSC1, C10orf76, PTAR1, RAB1A, CCDC40, EXOC1, EXOC6, SYCE3, PRAF2, CEP170, PKN3, NCKAP5L, TFPT, CCHCR1, YEATS4, TUFT1, RABGAP1L, GOLGA5, CLOCK, PSMD9, DZIP3, GRIPAP1, RCOR1, HMG20A, CCDC93, OIP5, PHF21A, PTRF, PHLDB3, HAUS6, GIT2, RPRD1A, ARNTL, MAX, RABGEF1, NUF2, THAP11, KDM1A, RABEP1, TRIM25 | RTN4RL1 | CUL3, KRTAP10-7, KRTAP10-8, KRTAP10-3, NOTCH2NL, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for VPS53_RTN4RL1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for VPS53_RTN4RL1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | VPS53 | C4014488 | PONTOCEREBELLAR HYPOPLASIA, TYPE 2E | 1 | UNIPROT |
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