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Fusion gene ID: 41591 |
FusionGeneSummary for VPS37B_MPHOSPH9 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: VPS37B_MPHOSPH9 | Fusion gene ID: 41591 | Hgene | Tgene | Gene symbol | VPS37B | MPHOSPH9 | Gene ID | 79720 | 10198 |
| Gene name | VPS37B, ESCRT-I subunit | M-phase phosphoprotein 9 | |
| Synonyms | - | MPP-9|MPP9 | |
| Cytomap | 12q24.31 | 12q24.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | vacuolar protein sorting-associated protein 37BESCRT-I complex subunit VPS37BhVps37Bvacuolar protein sorting 37 homolog Bvacuolar protein sorting 37B | M-phase phosphoprotein 9 | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | Q9H9H4 | Q99550 | |
| Ensembl transtripts involved in fusion gene | ENST00000267202, | ENST00000302349, ENST00000541076, ENST00000606320, ENST00000392425, ENST00000539639, | |
| Fusion gene scores | * DoF score | 7 X 2 X 6=84 | 4 X 4 X 4=64 |
| # samples | 7 | 4 | |
| ** MAII score | log2(7/84*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: VPS37B [Title/Abstract] AND MPHOSPH9 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-24-2026-01A | VPS37B | chr12 | 123380499 | - | MPHOSPH9 | chr12 | 123665757 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000267202 | ENST00000302349 | VPS37B | chr12 | 123380499 | - | MPHOSPH9 | chr12 | 123665757 | - |
| In-frame | ENST00000267202 | ENST00000541076 | VPS37B | chr12 | 123380499 | - | MPHOSPH9 | chr12 | 123665757 | - |
| In-frame | ENST00000267202 | ENST00000606320 | VPS37B | chr12 | 123380499 | - | MPHOSPH9 | chr12 | 123665757 | - |
| In-frame | ENST00000267202 | ENST00000392425 | VPS37B | chr12 | 123380499 | - | MPHOSPH9 | chr12 | 123665757 | - |
| 5CDS-intron | ENST00000267202 | ENST00000539639 | VPS37B | chr12 | 123380499 | - | MPHOSPH9 | chr12 | 123665757 | - |
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FusionProtFeatures for VPS37B_MPHOSPH9 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| VPS37B | MPHOSPH9 |
| Component of the ESCRT-I complex, a regulator ofvesicular trafficking process. Required for the sorting ofendocytic ubiquitinated cargos into multivesicular bodies. May beinvolved in cell growth and differentiation.{ECO:0000269|PubMed:15218037}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >MPHOSPH9 | chr12:123380499 | chr12:123665757 | ENST00000302349 | - | 8 | 20 | 1109_1174 | 595 | 1029 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >MPHOSPH9 | chr12:123380499 | chr12:123665757 | ENST00000302349 | - | 8 | 20 | 609_804 | 595 | 1029 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >MPHOSPH9 | chr12:123380499 | chr12:123665757 | ENST00000392425 | - | 8 | 20 | 1109_1174 | 595 | 1032 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >MPHOSPH9 | chr12:123380499 | chr12:123665757 | ENST00000392425 | - | 8 | 20 | 609_804 | 595 | 1032 | Coiled coil | Ontology_term=ECO:0000255 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >VPS37B | chr12:123380499 | chr12:123665757 | ENST00000267202 | - | 1 | 4 | 170_280 | 37 | 286 | Compositional bias | Note=Pro-rich |
| Hgene | >VPS37B | chr12:123380499 | chr12:123665757 | ENST00000267202 | - | 1 | 4 | 84_173 | 37 | 286 | Domain | VPS37 C-terminal |
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FusionGeneSequence for VPS37B_MPHOSPH9 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_VPS37B_ENST00000267202_chr12_123380499_-_MPHOSPH9_ENST00000302349_chr12_123665757_-_471aa MAGAGSEARFAGLSLVQLNELLEDEGQLTEMVQKMEELLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHE NMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRET SDTPIMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNSASQRSSSLPPSNRKSSTPTKREIMLTPVT VAYSPKRSPKENLSPGFSHLLSKNESSPIRFDILLDDLDTVPVSTLQRTNPRKQLQFLPLDDSEEKTYSEKATDNHVNHSSCPEPVPNGV KKVSVRTAWEKNKSVSYEQCKPVSVTPQGNDFEYTAKIRTLAETERFFDELTKEKDQIEAALSRMPSPGGRITLQTRLNQTPQICEESSH >In-frame_VPS37B_ENST00000267202_chr12_123380499_-_MPHOSPH9_ENST00000541076_chr12_123665757_-_474aa MAGAGSEARFAGLSLVQLNELLEDEGQLTEMVQKMEELLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHE NMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRET SDTPIMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNSASQRSSSLPPSNRKSSTPTKREIMLTPVT VAYSPKRSPKENLSPGFSHLLSKNESSPIRFDILLDDLDTVPVSTLQRTNPRKQLQFLPLDDSEEKTYSEKATDNHVNHSSCPEPVPNGV KKVSVRTAWEKNKSVSYEQCKPVSVTPQGNDFEYTAKIRTLAETERFFDELTKEKDQIEAALSRMPSPGGRITLQTRLNQEALEDRLERI >In-frame_VPS37B_ENST00000267202_chr12_123380499_-_MPHOSPH9_ENST00000606320_chr12_123665757_-_474aa MAGAGSEARFAGLSLVQLNELLEDEGQLTEMVQKMEELLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHE NMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRET SDTPIMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNSASQRSSSLPPSNRKSSTPTKREIMLTPVT VAYSPKRSPKENLSPGFSHLLSKNESSPIRFDILLDDLDTVPVSTLQRTNPRKQLQFLPLDDSEEKTYSEKATDNHVNHSSCPEPVPNGV KKVSVRTAWEKNKSVSYEQCKPVSVTPQGNDFEYTAKIRTLAETERFFDELTKEKDQIEAALSRMPSPGGRITLQTRLNQEALEDRLERI >In-frame_VPS37B_ENST00000267202_chr12_123380499_-_MPHOSPH9_ENST00000392425_chr12_123665757_-_474aa MAGAGSEARFAGLSLVQLNELLEDEGQLTEMVQKMEELLGEYESLGKEHRRVKDALNTTENKLLDAYTQISDLKRMISKLEAQVKQVEHE NMLSLRHNSRIHVRPSRANTLATSDVSRRKWLIPGAEYSIFTGQPLDTQDSNVDNQLEETCSLGHRSPLEKDSSPGSSSTSLLIKKQRET SDTPIMRALKELDEGKIFKNWGTQTEKEDTSNINPRQTETSVNASRSPEKCAQQRQKRLNSASQRSSSLPPSNRKSSTPTKREIMLTPVT VAYSPKRSPKENLSPGFSHLLSKNESSPIRFDILLDDLDTVPVSTLQRTNPRKQLQFLPLDDSEEKTYSEKATDNHVNHSSCPEPVPNGV KKVSVRTAWEKNKSVSYEQCKPVSVTPQGNDFEYTAKIRTLAETERFFDELTKEKDQIEAALSRMPSPGGRITLQTRLNQEALEDRLERI |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_VPS37B_ENST00000267202_chr12_123380499_-_MPHOSPH9_ENST00000302349_chr12_123665757_-_1413nt ATGGCGGGCGCCGGGAGCGAAGCCCGGTTCGCCGGGCTGTCGCTGGTGCAGCTCAACGAGCTGCTGGAGGACGAGGGCCAGCTGACGGAG ATGGTGCAGAAGATGGAGGAGCTTTTAGGAGAGTATGAGTCCCTTGGAAAAGAACACAGGAGAGTAAAGGATGCATTAAATACAACTGAG AACAAATTGCTTGATGCATATACTCAGATTTCTGATTTGAAAAGAATGATTTCAAAACTTGAAGCTCAGGTCAAGCAAGTAGAACATGAA AATATGTTAAGCCTTCGTCATAATTCTAGAATTCACGTGAGACCCTCGCGTGCCAACACACTAGCAACTTCAGACGTCAGCAGGCGGAAA TGGCTGATTCCAGGTGCAGAGTATTCCATCTTTACTGGCCAGCCTCTGGACACCCAGGACAGTAACGTGGATAACCAGCTGGAGGAAACC TGTAGCCTAGGGCACCGTTCACCTCTGGAAAAGGATTCTTCACCTGGAAGTTCATCAACAAGCTTGTTGATAAAAAAGCAAAGAGAGACT TCAGACACGCCGATCATGAGAGCTTTAAAAGAACTTGATGAGGGAAAAATATTTAAAAATTGGGGGACACAGACAGAGAAAGAGGACACC TCAAATATAAATCCTCGGCAAACTGAAACTTCAGTTAATGCAAGTCGTTCTCCAGAAAAGTGTGCCCAACAGAGACAAAAGAGACTTAAT TCGGCCTCACAGAGATCATCATCTTTACCACCTTCAAATCGTAAATCAAGTACTCCAACAAAAAGAGAGATTATGCTAACACCAGTGACT GTGGCTTATAGTCCAAAGCGATCCCCTAAAGAAAACTTGTCCCCAGGATTTAGTCATCTGCTTAGCAAAAATGAGAGCAGTCCAATTCGA TTTGATATACTTTTGGATGATTTAGATACTGTTCCTGTGTCTACATTACAACGTACCAATCCAAGAAAGCAACTCCAGTTTCTTCCTCTA GATGACTCGGAAGAAAAAACTTATTCTGAGAAAGCCACCGATAACCATGTTAATCATAGCTCTTGCCCTGAACCGGTGCCAAATGGAGTG AAGAAAGTATCTGTGAGAACAGCCTGGGAGAAGAATAAATCAGTTAGCTACGAACAGTGTAAGCCGGTTTCAGTCACTCCACAGGGGAAT GATTTTGAATATACAGCAAAAATTCGGACCCTAGCTGAAACAGAACGATTTTTTGATGAACTTACAAAAGAAAAGGACCAGATTGAGGCA GCACTAAGCAGGATGCCTTCTCCTGGAGGACGAATCACTTTACAGACAAGATTAAATCAGACCCCTCAGATATGTGAGGAATCAAGCCAT >In-frame_VPS37B_ENST00000267202_chr12_123380499_-_MPHOSPH9_ENST00000541076_chr12_123665757_-_1422nt ATGGCGGGCGCCGGGAGCGAAGCCCGGTTCGCCGGGCTGTCGCTGGTGCAGCTCAACGAGCTGCTGGAGGACGAGGGCCAGCTGACGGAG ATGGTGCAGAAGATGGAGGAGCTTTTAGGAGAGTATGAGTCCCTTGGAAAAGAACACAGGAGAGTAAAGGATGCATTAAATACAACTGAG AACAAATTGCTTGATGCATATACTCAGATTTCTGATTTGAAAAGAATGATTTCAAAACTTGAAGCTCAGGTCAAGCAAGTAGAACATGAA AATATGTTAAGCCTTCGTCATAATTCTAGAATTCACGTGAGACCCTCGCGTGCCAACACACTAGCAACTTCAGACGTCAGCAGGCGGAAA TGGCTGATTCCAGGTGCAGAGTATTCCATCTTTACTGGCCAGCCTCTGGACACCCAGGACAGTAACGTGGATAACCAGCTGGAGGAAACC TGTAGCCTAGGGCACCGTTCACCTCTGGAAAAGGATTCTTCACCTGGAAGTTCATCAACAAGCTTGTTGATAAAAAAGCAAAGAGAGACT TCAGACACGCCGATCATGAGAGCTTTAAAAGAACTTGATGAGGGAAAAATATTTAAAAATTGGGGGACACAGACAGAGAAAGAGGACACC TCAAATATAAATCCTCGGCAAACTGAAACTTCAGTTAATGCAAGTCGTTCTCCAGAAAAGTGTGCCCAACAGAGACAAAAGAGACTTAAT TCGGCCTCACAGAGATCATCATCTTTACCACCTTCAAATCGTAAATCAAGTACTCCAACAAAAAGAGAGATTATGCTAACACCAGTGACT GTGGCTTATAGTCCAAAGCGATCCCCTAAAGAAAACTTGTCCCCAGGATTTAGTCATCTGCTTAGCAAAAATGAGAGCAGTCCAATTCGA TTTGATATACTTTTGGATGATTTAGATACTGTTCCTGTGTCTACATTACAACGTACCAATCCAAGAAAGCAACTCCAGTTTCTTCCTCTA GATGACTCGGAAGAAAAAACTTATTCTGAGAAAGCCACCGATAACCATGTTAATCATAGCTCTTGCCCTGAACCGGTGCCAAATGGAGTG AAGAAAGTATCTGTGAGAACAGCCTGGGAGAAGAATAAATCAGTTAGCTACGAACAGTGTAAGCCGGTTTCAGTCACTCCACAGGGGAAT GATTTTGAATATACAGCAAAAATTCGGACCCTAGCTGAAACAGAACGATTTTTTGATGAACTTACAAAAGAAAAGGACCAGATTGAGGCA GCACTAAGCAGGATGCCTTCTCCTGGAGGACGAATCACTTTACAGACAAGATTAAATCAGGAAGCCTTGGAAGATCGTTTGGAAAGGATT >In-frame_VPS37B_ENST00000267202_chr12_123380499_-_MPHOSPH9_ENST00000606320_chr12_123665757_-_1422nt ATGGCGGGCGCCGGGAGCGAAGCCCGGTTCGCCGGGCTGTCGCTGGTGCAGCTCAACGAGCTGCTGGAGGACGAGGGCCAGCTGACGGAG ATGGTGCAGAAGATGGAGGAGCTTTTAGGAGAGTATGAGTCCCTTGGAAAAGAACACAGGAGAGTAAAGGATGCATTAAATACAACTGAG AACAAATTGCTTGATGCATATACTCAGATTTCTGATTTGAAAAGAATGATTTCAAAACTTGAAGCTCAGGTCAAGCAAGTAGAACATGAA AATATGTTAAGCCTTCGTCATAATTCTAGAATTCACGTGAGACCCTCGCGTGCCAACACACTAGCAACTTCAGACGTCAGCAGGCGGAAA TGGCTGATTCCAGGTGCAGAGTATTCCATCTTTACTGGCCAGCCTCTGGACACCCAGGACAGTAACGTGGATAACCAGCTGGAGGAAACC TGTAGCCTAGGGCACCGTTCACCTCTGGAAAAGGATTCTTCACCTGGAAGTTCATCAACAAGCTTGTTGATAAAAAAGCAAAGAGAGACT TCAGACACGCCGATCATGAGAGCTTTAAAAGAACTTGATGAGGGAAAAATATTTAAAAATTGGGGGACACAGACAGAGAAAGAGGACACC TCAAATATAAATCCTCGGCAAACTGAAACTTCAGTTAATGCAAGTCGTTCTCCAGAAAAGTGTGCCCAACAGAGACAAAAGAGACTTAAT TCGGCCTCACAGAGATCATCATCTTTACCACCTTCAAATCGTAAATCAAGTACTCCAACAAAAAGAGAGATTATGCTAACACCAGTGACT GTGGCTTATAGTCCAAAGCGATCCCCTAAAGAAAACTTGTCCCCAGGATTTAGTCATCTGCTTAGCAAAAATGAGAGCAGTCCAATTCGA TTTGATATACTTTTGGATGATTTAGATACTGTTCCTGTGTCTACATTACAACGTACCAATCCAAGAAAGCAACTCCAGTTTCTTCCTCTA GATGACTCGGAAGAAAAAACTTATTCTGAGAAAGCCACCGATAACCATGTTAATCATAGCTCTTGCCCTGAACCGGTGCCAAATGGAGTG AAGAAAGTATCTGTGAGAACAGCCTGGGAGAAGAATAAATCAGTTAGCTACGAACAGTGTAAGCCGGTTTCAGTCACTCCACAGGGGAAT GATTTTGAATATACAGCAAAAATTCGGACCCTAGCTGAAACAGAACGATTTTTTGATGAACTTACAAAAGAAAAGGACCAGATTGAGGCA GCACTAAGCAGGATGCCTTCTCCTGGAGGACGAATCACTTTACAGACAAGATTAAATCAGGAAGCCTTGGAAGATCGTTTGGAAAGGATT >In-frame_VPS37B_ENST00000267202_chr12_123380499_-_MPHOSPH9_ENST00000392425_chr12_123665757_-_1422nt ATGGCGGGCGCCGGGAGCGAAGCCCGGTTCGCCGGGCTGTCGCTGGTGCAGCTCAACGAGCTGCTGGAGGACGAGGGCCAGCTGACGGAG ATGGTGCAGAAGATGGAGGAGCTTTTAGGAGAGTATGAGTCCCTTGGAAAAGAACACAGGAGAGTAAAGGATGCATTAAATACAACTGAG AACAAATTGCTTGATGCATATACTCAGATTTCTGATTTGAAAAGAATGATTTCAAAACTTGAAGCTCAGGTCAAGCAAGTAGAACATGAA AATATGTTAAGCCTTCGTCATAATTCTAGAATTCACGTGAGACCCTCGCGTGCCAACACACTAGCAACTTCAGACGTCAGCAGGCGGAAA TGGCTGATTCCAGGTGCAGAGTATTCCATCTTTACTGGCCAGCCTCTGGACACCCAGGACAGTAACGTGGATAACCAGCTGGAGGAAACC TGTAGCCTAGGGCACCGTTCACCTCTGGAAAAGGATTCTTCACCTGGAAGTTCATCAACAAGCTTGTTGATAAAAAAGCAAAGAGAGACT TCAGACACGCCGATCATGAGAGCTTTAAAAGAACTTGATGAGGGAAAAATATTTAAAAATTGGGGGACACAGACAGAGAAAGAGGACACC TCAAATATAAATCCTCGGCAAACTGAAACTTCAGTTAATGCAAGTCGTTCTCCAGAAAAGTGTGCCCAACAGAGACAAAAGAGACTTAAT TCGGCCTCACAGAGATCATCATCTTTACCACCTTCAAATCGTAAATCAAGTACTCCAACAAAAAGAGAGATTATGCTAACACCAGTGACT GTGGCTTATAGTCCAAAGCGATCCCCTAAAGAAAACTTGTCCCCAGGATTTAGTCATCTGCTTAGCAAAAATGAGAGCAGTCCAATTCGA TTTGATATACTTTTGGATGATTTAGATACTGTTCCTGTGTCTACATTACAACGTACCAATCCAAGAAAGCAACTCCAGTTTCTTCCTCTA GATGACTCGGAAGAAAAAACTTATTCTGAGAAAGCCACCGATAACCATGTTAATCATAGCTCTTGCCCTGAACCGGTGCCAAATGGAGTG AAGAAAGTATCTGTGAGAACAGCCTGGGAGAAGAATAAATCAGTTAGCTACGAACAGTGTAAGCCGGTTTCAGTCACTCCACAGGGGAAT GATTTTGAATATACAGCAAAAATTCGGACCCTAGCTGAAACAGAACGATTTTTTGATGAACTTACAAAAGAAAAGGACCAGATTGAGGCA GCACTAAGCAGGATGCCTTCTCCTGGAGGACGAATCACTTTACAGACAAGATTAAATCAGGAAGCCTTGGAAGATCGTTTGGAAAGGATT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_VPS37B_ENST00000267202_chr12_123380499_-_MPHOSPH9_ENST00000302349_chr12_123665757_-_1795nt GGGCTCACAGGCTGCGGGAACTTCCTTCCCACTGCCTGTTTTCCTTGGATCGCGGTATCTCTCTTCCTGGAGGAAAAAGGCTCTTATGAC CTCATGGCGCGCTCTCCCGAGCCGCAGTGACGTCATTAATGCGCTCACGCGTCACAGCCCAATCATAGGGCCCTTCCCCTCCCTTTAGAA GTCCCGACTGTCCCTGACACATTCCACTCCAAGCGAGCCGCGACACTTACGTCACGTCCGCCCGCCCGCGCGGTGATGACGTCACGACCC AGGGCTGGCGTCACGTGTCCCCCCCGCGGGGGGCGGCCCTTGAGGGCGGCGCTTCCGGTCGGCGGAGCCTGGTGGCCGCAGCGGCGGTGG CGACGACGGCCGAGACGTGGGGATGGCGGGCGCCGGGAGCGAAGCCCGGTTCGCCGGGCTGTCGCTGGTGCAGCTCAACGAGCTGCTGGA GGACGAGGGCCAGCTGACGGAGATGGTGCAGAAGATGGAGGAGCTTTTAGGAGAGTATGAGTCCCTTGGAAAAGAACACAGGAGAGTAAA GGATGCATTAAATACAACTGAGAACAAATTGCTTGATGCATATACTCAGATTTCTGATTTGAAAAGAATGATTTCAAAACTTGAAGCTCA GGTCAAGCAAGTAGAACATGAAAATATGTTAAGCCTTCGTCATAATTCTAGAATTCACGTGAGACCCTCGCGTGCCAACACACTAGCAAC TTCAGACGTCAGCAGGCGGAAATGGCTGATTCCAGGTGCAGAGTATTCCATCTTTACTGGCCAGCCTCTGGACACCCAGGACAGTAACGT GGATAACCAGCTGGAGGAAACCTGTAGCCTAGGGCACCGTTCACCTCTGGAAAAGGATTCTTCACCTGGAAGTTCATCAACAAGCTTGTT GATAAAAAAGCAAAGAGAGACTTCAGACACGCCGATCATGAGAGCTTTAAAAGAACTTGATGAGGGAAAAATATTTAAAAATTGGGGGAC ACAGACAGAGAAAGAGGACACCTCAAATATAAATCCTCGGCAAACTGAAACTTCAGTTAATGCAAGTCGTTCTCCAGAAAAGTGTGCCCA ACAGAGACAAAAGAGACTTAATTCGGCCTCACAGAGATCATCATCTTTACCACCTTCAAATCGTAAATCAAGTACTCCAACAAAAAGAGA GATTATGCTAACACCAGTGACTGTGGCTTATAGTCCAAAGCGATCCCCTAAAGAAAACTTGTCCCCAGGATTTAGTCATCTGCTTAGCAA AAATGAGAGCAGTCCAATTCGATTTGATATACTTTTGGATGATTTAGATACTGTTCCTGTGTCTACATTACAACGTACCAATCCAAGAAA GCAACTCCAGTTTCTTCCTCTAGATGACTCGGAAGAAAAAACTTATTCTGAGAAAGCCACCGATAACCATGTTAATCATAGCTCTTGCCC TGAACCGGTGCCAAATGGAGTGAAGAAAGTATCTGTGAGAACAGCCTGGGAGAAGAATAAATCAGTTAGCTACGAACAGTGTAAGCCGGT TTCAGTCACTCCACAGGGGAATGATTTTGAATATACAGCAAAAATTCGGACCCTAGCTGAAACAGAACGATTTTTTGATGAACTTACAAA AGAAAAGGACCAGATTGAGGCAGCACTAAGCAGGATGCCTTCTCCTGGAGGACGAATCACTTTACAGACAAGATTAAATCAGACCCCTCA >In-frame_VPS37B_ENST00000267202_chr12_123380499_-_MPHOSPH9_ENST00000541076_chr12_123665757_-_4396nt GGGCTCACAGGCTGCGGGAACTTCCTTCCCACTGCCTGTTTTCCTTGGATCGCGGTATCTCTCTTCCTGGAGGAAAAAGGCTCTTATGAC CTCATGGCGCGCTCTCCCGAGCCGCAGTGACGTCATTAATGCGCTCACGCGTCACAGCCCAATCATAGGGCCCTTCCCCTCCCTTTAGAA GTCCCGACTGTCCCTGACACATTCCACTCCAAGCGAGCCGCGACACTTACGTCACGTCCGCCCGCCCGCGCGGTGATGACGTCACGACCC AGGGCTGGCGTCACGTGTCCCCCCCGCGGGGGGCGGCCCTTGAGGGCGGCGCTTCCGGTCGGCGGAGCCTGGTGGCCGCAGCGGCGGTGG CGACGACGGCCGAGACGTGGGGATGGCGGGCGCCGGGAGCGAAGCCCGGTTCGCCGGGCTGTCGCTGGTGCAGCTCAACGAGCTGCTGGA GGACGAGGGCCAGCTGACGGAGATGGTGCAGAAGATGGAGGAGCTTTTAGGAGAGTATGAGTCCCTTGGAAAAGAACACAGGAGAGTAAA GGATGCATTAAATACAACTGAGAACAAATTGCTTGATGCATATACTCAGATTTCTGATTTGAAAAGAATGATTTCAAAACTTGAAGCTCA GGTCAAGCAAGTAGAACATGAAAATATGTTAAGCCTTCGTCATAATTCTAGAATTCACGTGAGACCCTCGCGTGCCAACACACTAGCAAC TTCAGACGTCAGCAGGCGGAAATGGCTGATTCCAGGTGCAGAGTATTCCATCTTTACTGGCCAGCCTCTGGACACCCAGGACAGTAACGT GGATAACCAGCTGGAGGAAACCTGTAGCCTAGGGCACCGTTCACCTCTGGAAAAGGATTCTTCACCTGGAAGTTCATCAACAAGCTTGTT GATAAAAAAGCAAAGAGAGACTTCAGACACGCCGATCATGAGAGCTTTAAAAGAACTTGATGAGGGAAAAATATTTAAAAATTGGGGGAC ACAGACAGAGAAAGAGGACACCTCAAATATAAATCCTCGGCAAACTGAAACTTCAGTTAATGCAAGTCGTTCTCCAGAAAAGTGTGCCCA ACAGAGACAAAAGAGACTTAATTCGGCCTCACAGAGATCATCATCTTTACCACCTTCAAATCGTAAATCAAGTACTCCAACAAAAAGAGA GATTATGCTAACACCAGTGACTGTGGCTTATAGTCCAAAGCGATCCCCTAAAGAAAACTTGTCCCCAGGATTTAGTCATCTGCTTAGCAA AAATGAGAGCAGTCCAATTCGATTTGATATACTTTTGGATGATTTAGATACTGTTCCTGTGTCTACATTACAACGTACCAATCCAAGAAA GCAACTCCAGTTTCTTCCTCTAGATGACTCGGAAGAAAAAACTTATTCTGAGAAAGCCACCGATAACCATGTTAATCATAGCTCTTGCCC TGAACCGGTGCCAAATGGAGTGAAGAAAGTATCTGTGAGAACAGCCTGGGAGAAGAATAAATCAGTTAGCTACGAACAGTGTAAGCCGGT TTCAGTCACTCCACAGGGGAATGATTTTGAATATACAGCAAAAATTCGGACCCTAGCTGAAACAGAACGATTTTTTGATGAACTTACAAA AGAAAAGGACCAGATTGAGGCAGCACTAAGCAGGATGCCTTCTCCTGGAGGACGAATCACTTTACAGACAAGATTAAATCAGGAAGCCTT GGAAGATCGTTTGGAAAGGATTAATCGAGAACTGGGTTCAGTTCGCATGACGCTAAAGAAATTCCATGTTTTGCGCACCTCTGCAAATCT TTGAGATTTGTAGCCATTAAATTTTGAGACATTTTTGTTTGCACTAATGTATAATTATGCAGTCAGAAAAGGCAAACTATTTTGTACTGT TTATAAGCCTTCAAACAGTAGTTTTACAATCATGCTATTCTTACACTTGCTATTTTATACTTCAAATGGCCACATATTTTCAAGATATTT TTGTTATGCTCAGGAATCTCTTGTATATTTTACTATTTAAAAAGCATTATTTTTAAATAGTATCTGTCTCCAATTTATATCAAGAATAAG GAAATATAAACAGAGGAAGCAGCTTGTTTCTAAACAAATAGTGTTATCCTTTTACAATTAACTGCACATCAATTTTATAGACTTGTTCTA CATTGTAAATACAATTCAGTTTTTAAAAAATAAAGCTTAATAGCTTCCATAATGATAGACTAGTACATGCTGAATACATAAACAATTACA GTGTACCTTGGATTTCAGTTGTGTTGAGGTTTTTAAAAAATGATAATGCAATTCGTATTTGAAACGTGTCTTAGAGTGAATATCAGAATA GTAATAATGGACTCTTGGAAAGCTTTGAAAACTACATGAATATAACTCATTTTCTTTAAACTTTATTGTCTGTAAGAGAAAAAAGAGAGA TTGTAATTCTCTAATTTTATCTTTTCTAAAAAAGTTAAACAATTGGAGAGCCCTCTCTGGAGGGCTCTCAGAGTAGCTCTCTGCCCATTG TTCTGAATTAACTTGTGTCCCACCCTGGACAATAAATGGACAGATAAACCCTTTGAAATACAAGCCACCACCCCGTGAGGGATTAAGAGG GCAGCCTGGTTTTCTTAGTGTGCATGGCTTCAGCTGTCCGTCATAGTTGTCATCTGGATATGTTCACCCCTTTCCACTCCTTCACCCTGG CCAAAAGGAAAATATTTCCACTGTAGGTGCTGTAAGAACACTAGACTTTAGATCATCACAATCTACTGTATTTGTTAATGGACAGGGAGT GTGTCCGGATGGAGCCTGGTGCCTTCCCCTCGGCCTTGCAGAGGGCTCCAGCCCACTGCCTCTGTGGTAGCCGCTGGCTCTCAGAAGTAG CACGTGGGCAGGAGTCTCTCCTCTGATCCAGGAGCATTGGCAGGTTTGTGTTGGGACTGCTGGTTAAGTTGGAGCTGTGTAACTACTTAG TTTTTGGTAGCCAATCAGAACGCAGTGCCCCACATATTCCAGCTCGGTACATGTTGATAAACAGACTCATCCAAACTTTCAAAATGGATT CGTACTAAACATGCTCAGGTTTTAAATTTTGGTTTGCTTTTGAGCTTTTCCTCTTTATGTGGCTCTTAATAATAAGTAGTTAGAATGAAC CAAGCCATCCCAGTTATTCCAAGCAGGCTCTCAAATGACCTTTGAGCACCCTTCACCTGGCTGGTCCCCAGGCCAGGGGTCCACAGCCCT GCTCCCTTCTCAGCAAGGAGGGTGGCCTGTCTGACAGTGCAGTTGAACCTTTGCTCCCTACTCTGCAACTTTTGAAGACTTCAGGCTAAT CAAAATTACTTATAATTAGAATCAAGTGCCTTTATTCTTGTTTTTTATTTTTATTTTATTTTATTTATTTATTTTTTTAGATGGAGTTTT GCCCTTGTTGCCCAGGCTGGAGTGCAATGGCATGATCTCAGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGC CTGCTGGGTAGCTGGGATTACAGGCATCTGCCACCACGCCCGGCTAATTTTGTGTGTGTGTATATGTCTATGTGTGTGTGTGTATGTATA TATCTTTTTTTTTTTTTTAGTAGAGATGGTGTTTCACCATATTGGCCAGGCTGGTCTCAAACTCCTGAACTCATGTGATCCGCCTGCCTT GGCCCCTCAAAGTGCTGGGATTACAGGCATGAGCCACCACACCCGGCCTATTCTTGGTATTCTTTATTCTTGGTTTTCTAGCCTTTAGAA AAAAAAAATCTAGTCTTGGTAAAGAAAATGTTCATTTTAATCAAGCTCCAGTACAGCTTGTGTCAAGACCTAGTAAGACCACCTTTAATG TGTTCCTGGATATGACATTAAAAACTAACTTGAAAATTGTTAGGATATTTCCTTGTTCCCTACTTTTATTGTAAAATCTACTACATTCTT AAGAATTAAAAAATGCCATTTCAGAAGAGATGATAGTTTTATCTTGCCAAGGAATTATCTTCTTAGTAGCCTATATTGGCTTATTCCAAA AAAGGCGTTAACCTCCATCAAAACATCTTCTGCGCCTCTCTCTCAGCATATGCTTTGATATTTGAAGTGTGTAATAGATTGGAGCTATCA GTCACTTATTTCTAAAAAATGTATTCTTTTTTCTTCATAGCTGTGAAGAGGGATACCAAGGAAAGTTCTTTCTGCTGTCTTTCTCTTCGG TAATGCTTATCTTATGAACACTCAACTGAAAAAACACTCCACCTAAAAGCAGGAAAGATGGCAATTCTAAATAGCAGCTATTATCCCCGG >In-frame_VPS37B_ENST00000267202_chr12_123380499_-_MPHOSPH9_ENST00000606320_chr12_123665757_-_4396nt GGGCTCACAGGCTGCGGGAACTTCCTTCCCACTGCCTGTTTTCCTTGGATCGCGGTATCTCTCTTCCTGGAGGAAAAAGGCTCTTATGAC CTCATGGCGCGCTCTCCCGAGCCGCAGTGACGTCATTAATGCGCTCACGCGTCACAGCCCAATCATAGGGCCCTTCCCCTCCCTTTAGAA GTCCCGACTGTCCCTGACACATTCCACTCCAAGCGAGCCGCGACACTTACGTCACGTCCGCCCGCCCGCGCGGTGATGACGTCACGACCC AGGGCTGGCGTCACGTGTCCCCCCCGCGGGGGGCGGCCCTTGAGGGCGGCGCTTCCGGTCGGCGGAGCCTGGTGGCCGCAGCGGCGGTGG CGACGACGGCCGAGACGTGGGGATGGCGGGCGCCGGGAGCGAAGCCCGGTTCGCCGGGCTGTCGCTGGTGCAGCTCAACGAGCTGCTGGA GGACGAGGGCCAGCTGACGGAGATGGTGCAGAAGATGGAGGAGCTTTTAGGAGAGTATGAGTCCCTTGGAAAAGAACACAGGAGAGTAAA GGATGCATTAAATACAACTGAGAACAAATTGCTTGATGCATATACTCAGATTTCTGATTTGAAAAGAATGATTTCAAAACTTGAAGCTCA GGTCAAGCAAGTAGAACATGAAAATATGTTAAGCCTTCGTCATAATTCTAGAATTCACGTGAGACCCTCGCGTGCCAACACACTAGCAAC TTCAGACGTCAGCAGGCGGAAATGGCTGATTCCAGGTGCAGAGTATTCCATCTTTACTGGCCAGCCTCTGGACACCCAGGACAGTAACGT GGATAACCAGCTGGAGGAAACCTGTAGCCTAGGGCACCGTTCACCTCTGGAAAAGGATTCTTCACCTGGAAGTTCATCAACAAGCTTGTT GATAAAAAAGCAAAGAGAGACTTCAGACACGCCGATCATGAGAGCTTTAAAAGAACTTGATGAGGGAAAAATATTTAAAAATTGGGGGAC ACAGACAGAGAAAGAGGACACCTCAAATATAAATCCTCGGCAAACTGAAACTTCAGTTAATGCAAGTCGTTCTCCAGAAAAGTGTGCCCA ACAGAGACAAAAGAGACTTAATTCGGCCTCACAGAGATCATCATCTTTACCACCTTCAAATCGTAAATCAAGTACTCCAACAAAAAGAGA GATTATGCTAACACCAGTGACTGTGGCTTATAGTCCAAAGCGATCCCCTAAAGAAAACTTGTCCCCAGGATTTAGTCATCTGCTTAGCAA AAATGAGAGCAGTCCAATTCGATTTGATATACTTTTGGATGATTTAGATACTGTTCCTGTGTCTACATTACAACGTACCAATCCAAGAAA GCAACTCCAGTTTCTTCCTCTAGATGACTCGGAAGAAAAAACTTATTCTGAGAAAGCCACCGATAACCATGTTAATCATAGCTCTTGCCC TGAACCGGTGCCAAATGGAGTGAAGAAAGTATCTGTGAGAACAGCCTGGGAGAAGAATAAATCAGTTAGCTACGAACAGTGTAAGCCGGT TTCAGTCACTCCACAGGGGAATGATTTTGAATATACAGCAAAAATTCGGACCCTAGCTGAAACAGAACGATTTTTTGATGAACTTACAAA AGAAAAGGACCAGATTGAGGCAGCACTAAGCAGGATGCCTTCTCCTGGAGGACGAATCACTTTACAGACAAGATTAAATCAGGAAGCCTT GGAAGATCGTTTGGAAAGGATTAATCGAGAACTGGGTTCAGTTCGCATGACGCTAAAGAAATTCCATGTTTTGCGCACCTCTGCAAATCT TTGAGATTTGTAGCCATTAAATTTTGAGACATTTTTGTTTGCACTAATGTATAATTATGCAGTCAGAAAAGGCAAACTATTTTGTACTGT TTATAAGCCTTCAAACAGTAGTTTTACAATCATGCTATTCTTACACTTGCTATTTTATACTTCAAATGGCCACATATTTTCAAGATATTT TTGTTATGCTCAGGAATCTCTTGTATATTTTACTATTTAAAAAGCATTATTTTTAAATAGTATCTGTCTCCAATTTATATCAAGAATAAG GAAATATAAACAGAGGAAGCAGCTTGTTTCTAAACAAATAGTGTTATCCTTTTACAATTAACTGCACATCAATTTTATAGACTTGTTCTA CATTGTAAATACAATTCAGTTTTTAAAAAATAAAGCTTAATAGCTTCCATAATGATAGACTAGTACATGCTGAATACATAAACAATTACA GTGTACCTTGGATTTCAGTTGTGTTGAGGTTTTTAAAAAATGATAATGCAATTCGTATTTGAAACGTGTCTTAGAGTGAATATCAGAATA GTAATAATGGACTCTTGGAAAGCTTTGAAAACTACATGAATATAACTCATTTTCTTTAAACTTTATTGTCTGTAAGAGAAAAAAGAGAGA TTGTAATTCTCTAATTTTATCTTTTCTAAAAAAGTTAAACAATTGGAGAGCCCTCTCTGGAGGGCTCTCAGAGTAGCTCTCTGCCCATTG TTCTGAATTAACTTGTGTCCCACCCTGGACAATAAATGGACAGATAAACCCTTTGAAATACAAGCCACCACCCCGTGAGGGATTAAGAGG GCAGCCTGGTTTTCTTAGTGTGCATGGCTTCAGCTGTCCGTCATAGTTGTCATCTGGATATGTTCACCCCTTTCCACTCCTTCACCCTGG CCAAAAGGAAAATATTTCCACTGTAGGTGCTGTAAGAACACTAGACTTTAGATCATCACAATCTACTGTATTTGTTAATGGACAGGGAGT GTGTCCGGATGGAGCCTGGTGCCTTCCCCTCGGCCTTGCAGAGGGCTCCAGCCCACTGCCTCTGTGGTAGCCGCTGGCTCTCAGAAGTAG CACGTGGGCAGGAGTCTCTCCTCTGATCCAGGAGCATTGGCAGGTTTGTGTTGGGACTGCTGGTTAAGTTGGAGCTGTGTAACTACTTAG TTTTTGGTAGCCAATCAGAACGCAGTGCCCCACATATTCCAGCTCGGTACATGTTGATAAACAGACTCATCCAAACTTTCAAAATGGATT CGTACTAAACATGCTCAGGTTTTAAATTTTGGTTTGCTTTTGAGCTTTTCCTCTTTATGTGGCTCTTAATAATAAGTAGTTAGAATGAAC CAAGCCATCCCAGTTATTCCAAGCAGGCTCTCAAATGACCTTTGAGCACCCTTCACCTGGCTGGTCCCCAGGCCAGGGGTCCACAGCCCT GCTCCCTTCTCAGCAAGGAGGGTGGCCTGTCTGACAGTGCAGTTGAACCTTTGCTCCCTACTCTGCAACTTTTGAAGACTTCAGGCTAAT CAAAATTACTTATAATTAGAATCAAGTGCCTTTATTCTTGTTTTTTATTTTTATTTTATTTTATTTATTTATTTTTTTAGATGGAGTTTT GCCCTTGTTGCCCAGGCTGGAGTGCAATGGCATGATCTCAGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGC CTGCTGGGTAGCTGGGATTACAGGCATCTGCCACCACGCCCGGCTAATTTTGTGTGTGTGTATATGTCTATGTGTGTGTGTGTATGTATA TATCTTTTTTTTTTTTTTAGTAGAGATGGTGTTTCACCATATTGGCCAGGCTGGTCTCAAACTCCTGAACTCATGTGATCCGCCTGCCTT GGCCCCTCAAAGTGCTGGGATTACAGGCATGAGCCACCACACCCGGCCTATTCTTGGTATTCTTTATTCTTGGTTTTCTAGCCTTTAGAA AAAAAAAATCTAGTCTTGGTAAAGAAAATGTTCATTTTAATCAAGCTCCAGTACAGCTTGTGTCAAGACCTAGTAAGACCACCTTTAATG TGTTCCTGGATATGACATTAAAAACTAACTTGAAAATTGTTAGGATATTTCCTTGTTCCCTACTTTTATTGTAAAATCTACTACATTCTT AAGAATTAAAAAATGCCATTTCAGAAGAGATGATAGTTTTATCTTGCCAAGGAATTATCTTCTTAGTAGCCTATATTGGCTTATTCCAAA AAAGGCGTTAACCTCCATCAAAACATCTTCTGCGCCTCTCTCTCAGCATATGCTTTGATATTTGAAGTGTGTAATAGATTGGAGCTATCA GTCACTTATTTCTAAAAAATGTATTCTTTTTTCTTCATAGCTGTGAAGAGGGATACCAAGGAAAGTTCTTTCTGCTGTCTTTCTCTTCGG TAATGCTTATCTTATGAACACTCAACTGAAAAAACACTCCACCTAAAAGCAGGAAAGATGGCAATTCTAAATAGCAGCTATTATCCCCGG >In-frame_VPS37B_ENST00000267202_chr12_123380499_-_MPHOSPH9_ENST00000392425_chr12_123665757_-_2210nt GGGCTCACAGGCTGCGGGAACTTCCTTCCCACTGCCTGTTTTCCTTGGATCGCGGTATCTCTCTTCCTGGAGGAAAAAGGCTCTTATGAC CTCATGGCGCGCTCTCCCGAGCCGCAGTGACGTCATTAATGCGCTCACGCGTCACAGCCCAATCATAGGGCCCTTCCCCTCCCTTTAGAA GTCCCGACTGTCCCTGACACATTCCACTCCAAGCGAGCCGCGACACTTACGTCACGTCCGCCCGCCCGCGCGGTGATGACGTCACGACCC AGGGCTGGCGTCACGTGTCCCCCCCGCGGGGGGCGGCCCTTGAGGGCGGCGCTTCCGGTCGGCGGAGCCTGGTGGCCGCAGCGGCGGTGG CGACGACGGCCGAGACGTGGGGATGGCGGGCGCCGGGAGCGAAGCCCGGTTCGCCGGGCTGTCGCTGGTGCAGCTCAACGAGCTGCTGGA GGACGAGGGCCAGCTGACGGAGATGGTGCAGAAGATGGAGGAGCTTTTAGGAGAGTATGAGTCCCTTGGAAAAGAACACAGGAGAGTAAA GGATGCATTAAATACAACTGAGAACAAATTGCTTGATGCATATACTCAGATTTCTGATTTGAAAAGAATGATTTCAAAACTTGAAGCTCA GGTCAAGCAAGTAGAACATGAAAATATGTTAAGCCTTCGTCATAATTCTAGAATTCACGTGAGACCCTCGCGTGCCAACACACTAGCAAC TTCAGACGTCAGCAGGCGGAAATGGCTGATTCCAGGTGCAGAGTATTCCATCTTTACTGGCCAGCCTCTGGACACCCAGGACAGTAACGT GGATAACCAGCTGGAGGAAACCTGTAGCCTAGGGCACCGTTCACCTCTGGAAAAGGATTCTTCACCTGGAAGTTCATCAACAAGCTTGTT GATAAAAAAGCAAAGAGAGACTTCAGACACGCCGATCATGAGAGCTTTAAAAGAACTTGATGAGGGAAAAATATTTAAAAATTGGGGGAC ACAGACAGAGAAAGAGGACACCTCAAATATAAATCCTCGGCAAACTGAAACTTCAGTTAATGCAAGTCGTTCTCCAGAAAAGTGTGCCCA ACAGAGACAAAAGAGACTTAATTCGGCCTCACAGAGATCATCATCTTTACCACCTTCAAATCGTAAATCAAGTACTCCAACAAAAAGAGA GATTATGCTAACACCAGTGACTGTGGCTTATAGTCCAAAGCGATCCCCTAAAGAAAACTTGTCCCCAGGATTTAGTCATCTGCTTAGCAA AAATGAGAGCAGTCCAATTCGATTTGATATACTTTTGGATGATTTAGATACTGTTCCTGTGTCTACATTACAACGTACCAATCCAAGAAA GCAACTCCAGTTTCTTCCTCTAGATGACTCGGAAGAAAAAACTTATTCTGAGAAAGCCACCGATAACCATGTTAATCATAGCTCTTGCCC TGAACCGGTGCCAAATGGAGTGAAGAAAGTATCTGTGAGAACAGCCTGGGAGAAGAATAAATCAGTTAGCTACGAACAGTGTAAGCCGGT TTCAGTCACTCCACAGGGGAATGATTTTGAATATACAGCAAAAATTCGGACCCTAGCTGAAACAGAACGATTTTTTGATGAACTTACAAA AGAAAAGGACCAGATTGAGGCAGCACTAAGCAGGATGCCTTCTCCTGGAGGACGAATCACTTTACAGACAAGATTAAATCAGGAAGCCTT GGAAGATCGTTTGGAAAGGATTAATCGAGAACTGGGTTCAGTTCGCATGACGCTAAAGAAATTCCATGTTTTGCGCACCTCTGCAAATCT TTGAGATTTGTAGCCATTAAATTTTGAGACATTTTTGTTTGCACTAATGTATAATTATGCAGTCAGAAAAGGCAAACTATTTTGTACTGT TTATAAGCCTTCAAACAGTAGTTTTACAATCATGCTATTCTTACACTTGCTATTTTATACTTCAAATGGCCACATATTTTCAAGATATTT TTGTTATGCTCAGGAATCTCTTGTATATTTTACTATTTAAAAAGCATTATTTTTAAATAGTATCTGTCTCCAATTTATATCAAGAATAAG GAAATATAAACAGAGGAAGCAGCTTGTTTCTAAACAAATAGTGTTATCCTTTTACAATTAACTGCACATCAATTTTATAGACTTGTTCTA |
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FusionGenePPI for VPS37B_MPHOSPH9 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| VPS37B | TSG101, VPS28, SH3KBP1, CEP55, WDR12, USP14, XPO7, UNC13D, XPO1, MVB12A, AES, BYSL, ERCC1, PRKAA1, QARS, SMARCD1, NCK2, SORBS3, SH3YL1, DCUN1D1, CDC73, UBASH3B, FBF1, DNAJB1, NIF3L1, RPRD1A, WARS, YBX1, UBAP1, GRB2 | MPHOSPH9 | USP11, YWHAZ, YWHAG, SVIL, LATS2, CCDC67, KIAA0753, CCDC14, MED4, OFD1, PCM1, CEP97, CEP104, CEP162, CEP290, CEP120, CNTROB, SPICE1, CEP128, CEP135, CEP63, CEP89, CNTRL, NINL, ODF2, RPGRIP1L, POC5, CENPJ, XPO1, CDC14A |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | VPS37B | chr12:123380499 | chr12:123665757 | ENST00000267202 | - | 1 | 4 | 50_170 | 37 | 286 | IST1 |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for VPS37B_MPHOSPH9 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for VPS37B_MPHOSPH9 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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