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Fusion gene ID: 41544 |
FusionGeneSummary for VPS13C_HERC1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: VPS13C_HERC1 | Fusion gene ID: 41544 | Hgene | Tgene | Gene symbol | VPS13C | HERC1 | Gene ID | 54832 | 8925 |
| Gene name | vacuolar protein sorting 13 homolog C | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 | |
| Synonyms | PARK23 | MDFPMR|p532|p619 | |
| Cytomap | 15q22.2 | 15q22.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | vacuolar protein sorting-associated protein 13C | probable E3 ubiquitin-protein ligase HERC1HECT domain and RCC1-like domain-containing protein 1HECT-type E3 ubiquitin transferase HERC1guanine nucleotide exchange factor p532hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q709C8 | Q15751 | |
| Ensembl transtripts involved in fusion gene | ENST00000249837, ENST00000261517, ENST00000395896, ENST00000395898, ENST00000558919, | ENST00000443617, | |
| Fusion gene scores | * DoF score | 13 X 13 X 7=1183 | 8 X 8 X 5=320 |
| # samples | 13 | 8 | |
| ** MAII score | log2(13/1183*10)=-3.18586654531133 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/320*10)=-2 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: VPS13C [Title/Abstract] AND HERC1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | STAD | TCGA-FP-8631-01A | VPS13C | chr15 | 62232846 | - | HERC1 | chr15 | 63904755 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000249837 | ENST00000443617 | VPS13C | chr15 | 62232846 | - | HERC1 | chr15 | 63904755 | - |
| In-frame | ENST00000261517 | ENST00000443617 | VPS13C | chr15 | 62232846 | - | HERC1 | chr15 | 63904755 | - |
| In-frame | ENST00000395896 | ENST00000443617 | VPS13C | chr15 | 62232846 | - | HERC1 | chr15 | 63904755 | - |
| In-frame | ENST00000395898 | ENST00000443617 | VPS13C | chr15 | 62232846 | - | HERC1 | chr15 | 63904755 | - |
| intron-3CDS | ENST00000558919 | ENST00000443617 | VPS13C | chr15 | 62232846 | - | HERC1 | chr15 | 63904755 | - |
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FusionProtFeatures for VPS13C_HERC1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| VPS13C | HERC1 |
| Necessary for proper mitochondrial function andmaintenance of mitochondrial transmembrane potential. Involved inthe regulation of PINK1/PRKN-mediated mitophagy in response tomitochondrial depolarization. {ECO:0000269|PubMed:26942284}. | Involved in membrane trafficking via some guaninenucleotide exchange factor (GEF) activity and its ability to bindclathrin. Acts as a GEF for Arf and Rab, by exchanging bound GDPfor free GTP. Binds phosphatidylinositol 4,5-bisphosphate, whichis required for GEF activity. May also act as a E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directlytransfers the ubiquitin to targeted substrates.{ECO:0000269|PubMed:15642342, ECO:0000269|PubMed:8861955,ECO:0000269|PubMed:9233772}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | VPS13C | chr15:62232846 | chr15:63904755 | ENST00000249837 | - | 45 | 83 | 145_179 | 1824 | 3711 | Compositional bias | Lys-rich |
| Hgene | VPS13C | chr15:62232846 | chr15:63904755 | ENST00000261517 | - | 47 | 85 | 145_179 | 1867 | 3754 | Compositional bias | Lys-rich |
| Hgene | VPS13C | chr15:62232846 | chr15:63904755 | ENST00000395896 | - | 47 | 82 | 145_179 | 1867 | 3629 | Compositional bias | Lys-rich |
| Hgene | VPS13C | chr15:62232846 | chr15:63904755 | ENST00000395898 | - | 45 | 80 | 145_179 | 1824 | 3586 | Compositional bias | Lys-rich |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 1349_1378 | 4698 | 4862 | Compositional bias | Note=Glu-rich |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 2002_2193 | 4698 | 4862 | Domain | B30.2/SPRY |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 4501_4848 | 4698 | 4862 | Domain | HECT |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 3426_3465 | 4698 | 4862 | Repeat | Note=WD 1 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 3484_3522 | 4698 | 4862 | Repeat | Note=WD 2 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 3524_3572 | 4698 | 4862 | Repeat | Note=WD 3 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 3580_3619 | 4698 | 4862 | Repeat | Note=WD 4 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 3624_3663 | 4698 | 4862 | Repeat | Note=WD 5 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 3667_3713 | 4698 | 4862 | Repeat | Note=WD 6 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 371_420 | 4698 | 4862 | Repeat | Note=RCC1 1 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 3745_3784 | 4698 | 4862 | Repeat | Note=WD 7 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 3996_4044 | 4698 | 4862 | Repeat | Note=RCC1 8 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 4046_4099 | 4698 | 4862 | Repeat | Note=RCC1 9 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 4101_4151 | 4698 | 4862 | Repeat | Note=RCC1 10 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 4153_4203 | 4698 | 4862 | Repeat | Note=RCC1 11 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 4205_4256 | 4698 | 4862 | Repeat | Note=RCC1 12 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 421_475 | 4698 | 4862 | Repeat | Note=RCC1 2 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 4258_4308 | 4698 | 4862 | Repeat | Note=RCC1 13 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 4310_4360 | 4698 | 4862 | Repeat | Note=RCC1 14 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 476_528 | 4698 | 4862 | Repeat | Note=RCC1 3 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 529_578 | 4698 | 4862 | Repeat | Note=RCC1 4 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 580_631 | 4698 | 4862 | Repeat | Note=RCC1 5 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 633_682 | 4698 | 4862 | Repeat | Note=RCC1 6 |
| Tgene | HERC1 | chr15:62232846 | chr15:63904755 | ENST00000443617 | - | 75 | 78 | 683_735 | 4698 | 4862 | Repeat | Note=RCC1 7 |
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FusionGeneSequence for VPS13C_HERC1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_VPS13C_ENST00000249837_chr15_62232846_-_HERC1_ENST00000443617_chr15_63904755_-_1988aa MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLV VPGASIKYDAVKEEKSLQDVKQKELSRIEEALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAES ELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIP ETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKER TATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPII SGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALV ASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKES LSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKE PLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPFSEPSSSEKESELK PLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERAASSMKDLAQKSFR LLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ RNLAAAWYVQIPGMEIKGKLKPMQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEISVEVLKKVVRYREVDEQHQLVQWFWHTLEEF SNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCRSIDMDNYMLSRNVDNA >In-frame_VPS13C_ENST00000261517_chr15_62232846_-_HERC1_ENST00000443617_chr15_63904755_-_2031aa MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLV VPGASIKYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRS REQILDQLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQV EVIRSGQKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQ PVEVIYDAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGL PLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDL LKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDL YTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDS MNVSLNQEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQR LKVSFASLDLVLHLEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHK FFMSLLNFLNNFQTAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVAAVREGMSWIVPVPLLSLLTAK QLEQMVCGMPEISVEVLKKVVRYREVDEQHQLVQWFWHTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTC >In-frame_VPS13C_ENST00000395896_chr15_62232846_-_HERC1_ENST00000443617_chr15_63904755_-_2031aa MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLV VPGASIKYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKD TFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRS REQILDQLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKY KPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQV EVIRSGQKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTS VTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQ PVEVIYDAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGT FQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGL PLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKA AEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDL LKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSD IIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDL YTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTN AVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDS MNVSLNQEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMK KSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQR LKVSFASLDLVLHLEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIA DIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHK FFMSLLNFLNNFQTAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSL PPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVAAVREGMSWIVPVPLLSLLTAK QLEQMVCGMPEISVEVLKKVVRYREVDEQHQLVQWFWHTLEEFSNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTC >In-frame_VPS13C_ENST00000395898_chr15_62232846_-_HERC1_ENST00000443617_chr15_63904755_-_1988aa MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLV VPGASIKYDAVKEEKSLQDVKQKELSRIEEALQKAAEKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLG ELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAES ELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQ LLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIP ETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWY ITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKER TATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARA EETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPII SGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLG TEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALV ASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQ SLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKES LSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYR TVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKE PLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFD FTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPFSEPSSSEKESELK PLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVS ILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERAASSMKDLAQKSFR LLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQ RNLAAAWYVQIPGMEIKGKLKPMQVAAVREGMSWIVPVPLLSLLTAKQLEQMVCGMPEISVEVLKKVVRYREVDEQHQLVQWFWHTLEEF SNEERVLFMRFVSGRSRLPANTADISQRFQIMKVDRPYDSLPTSQTCFFQLRLPPYSSQLVMAERLRYAINNCRSIDMDNYMLSRNVDNA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_VPS13C_ENST00000249837_chr15_62232846_-_HERC1_ENST00000443617_chr15_63904755_-_5964nt ATGGTGCTGGAGTCGGTGGTCGCGGACTTGCTGAACCGCTTCCTGGGGGACTATGTGGAGAACCTGAACAAGTCCCAGCTGAAGCTGGGC ATCTGGGGCGGAAATGTGGCTTTAGATAATCTACAGATAAAAGAAAATGCCCTGAGTGAATTGGATGTTCCTTTTAAAGTCAAGGCTGGC CAAATTGATAAATTAACTTTGAAGATTCCTTGGAAGAACCTTTATGGAGAAGCAGTTGTTGCGACCCTGGAAGGATTATACCTGCTTGTT GTCCCTGGAGCAAGTATTAAGTATGATGCTGTAAAAGAAGAAAAATCCTTGCAGGATGTTAAACAGAAAGAGCTATCCCGAATTGAAGAA GCCCTTCAAAAAGCAGCAGAAAAAGATAAGCCAAAAGAAGCCAAAAAGGATACATTTGTGGAAAAATTGGCAACTCAAGTAATAAAAAAT GTACAAGTAAAAATCACAGATATTCACATTAAATATGAAGATGATGTCACTGATCCAAAGCGGCCTCTTTCATTTGGTGTCACACTGGGA GAGCTTAGTCTACTGACTGCAAATGAACACTGGACTCCATGCATATTAAATGAAGCAGACAAAATTATATACAAGCTTATACGACTTGAT AGTCTTAGCGCCTACTGGAATGTAAATTGCAGCATGTCTTACCAGAGATCAAGGGAACAGATTTTGGATCAGCTGAAAAATGAAATTCTT ACAAGTGGAAATATACCCCCAAATTATCAATACATTTTCCAGCCAATATCAGCCTCTGCAAAACTCTACATGAATCCTTATGCAGAATCA GAGCTCAAAACGCCCAAACTGGATTGCAACATAGAAATACAAAATATTGCCATTGAACTGACCAAACCTCAGTACTTAAGTATGATTGAC CTTTTGGAGTCAGTGGATTATATGGTTAGGAATGCGCCTTATAGGAAATACAAGCCTTATTTACCACTTCATACCAATGGTCGACGATGG TGGAAATATGCAATTGATTCTGTTCTTGAAGTTCATATAAGAAGGTATACACAGATGTGGTCATGGAGTAACATAAAAAAGCACAGGCAG TTACTCAAGAGTTATAAAATTGCCTACAAAAACAAGTTAACACAGTCTAAAGTCTCAGAAGAAATACAGAAAGAAATTCAGGACTTGGAG AAGACTCTAGATGTTTTTAACATAATTTTAGCAAGGCAACAAGCACAAGTTGAGGTGATTCGGTCTGGGCAAAAATTAAGGAAAAAGTCT GCTGACACAGGCGAGAAACGTGGAGGCTGGTTTAGTGGGTTGTGGGGTAAGAAAGAGTCTAAGAAAAAGGACGAAGAATCATTGATTCCT GAAACTATTGATGACCTTATGACTCCAGAGGAAAAAGATAAACTCTTCACTGCCATTGGTTATAGTGAGAGTACCCACAACCTAACTTTA CCTAAGCAGTATGTTGCCCATATTATGACCCTGAAGTTAGTAAGCACCTCTGTTACGATAAGAGAAAACAAGAATATTCCAGAAATACTA AAAATTCAGATAATTGGCCTGGGCACTCAAGTATCTCAGCGACCAGGAGCACAAGCACTTAAGGTAGAAGCGAAATTAGAACACTGGTAT ATAACAGGTTTGAGACAGCAGGATATTGTGCCATCACTTGTGGCTTCAATTGGTGACACTACATCATCCTTGCTTAAAATTAAATTTGAA ACCAATCCGGAGGATAGTCCTGCTGACCAGACTCTGATTGTTCAGTCCCAGCCTGTGGAGGTCATCTATGATGCTAAAACTGTCAATGCA GTGGTTGAATTCTTTCAATCAAATAAGGGATTGGATCTTGAGCAAATAACATCAGCAACATTGATGAAGCTGGAAGAAATTAAGGAGAGA ACAGCTACAGGACTTACACATATTATTGAAACTCGAAAAGTCCTTGATTTAAGGATAAATCTGAAGCCTTCTTATCTAGTAGTTCCACAG ACGGGTTTCCACCATGAAAAGTCAGATCTTCTGATTTTAGATTTTGGTACATTTCAGCTCAACAGTAAAGATCAAGGTTTACAGAAGACT ACTAATTCATCTCTGGAAGAAATAATGGATAAGGCATATGACAAGTTTGATGTTGAAATAAAAAATGTACAACTACTTTTTGCAAGAGCA GAGGAAACCTGGAAAAAGTGTCGATTTCAGCATCCATCAACTATGCATATATTGCAACCCATGGATATTCATGTTGAGTTGGCTAAGGCC ATGGTAGAAAAAGACATTAGAATGGCCAGATTTAAAGTGTCAGGAGGACTTCCTTTGATGCATGTGAGAATTTCTGACCAGAAGATGAAA GATGTGCTATATTTGATGAACAGTATACCTTTGCCACAGAAATCATCAGCCCAGTCTCCAGAGAGACAGGTATCCTCAATTCCTATTATT TCAGGTGGTACAAAAGGTCTACTTGGTACTTCACTATTGCTAGACACTGTGGAATCAGAGTCTGATGATGAGTATTTTGATGCTGAAGAT GGAGAACCACAGACTTGTAAAAGTATGAAAGGATCAGAACTTAAAAAAGCTGCAGAGGTCCCAAATGAGGAGCTCATCAATCTTCTACTC AAGTTTGAAATTAAAGAAGTGATTTTGGAATTTACTAAACAGCAGAAAGAAGAAGATACAATTCTAGTATTTAATGTTACTCAGTTAGGA ACAGAGGCCACAATGAGAACATTTGACTTAACTGTGGTATCTTATTTAAAGAAAATCAGCTTGGATTATCATGAAATTGAAGGATCCAAA AGGAAGCCCCTTCACTTGATTAGCTCTTCTGACAAACCTGGATTAGATCTTTTGAAAGTGGAGTATATTAAGGCTGATAAGAATGGACCT AGTTTTCAAACTGCTTTTGGAAAAACTGAACAAACAGTTAAGGTGGCCTTTTCATCTTTAAATCTGTTGCTGCAAACACAAGCTCTTGTC GCTTCTATTAATTACCTCACAACCATTATTCCATCTGATGATCAAAGCATAAGTGTTGCTAAGGAGGTACAAATTTCAACTGAAAAACAA CAAAAAAATTCAACTCTGCCAAAAGCGATTGTATCCTCCAGAGATAGTGACATTATTGATTTCAGGCTATTTGCCAAGTTGAATGCTTTC TGTGTCATTGTTTGCAACGAAAAGAACAATATCGCCGAAATCAAGATTCAAGGACTGGATTCCTCCCTTTCTCTCCAGTCAAGAAAGCAG TCACTTTTTGCCCGACTAGAAAATATTATTGTCACAGATGTTGATCCAAAGACAGTTCATAAGAAAGCTGTGTCAATAATGGGAAATGAA GTTTTCCGTTTTAATTTGGATTTGTATCCAGATGCTACTGAGGGGGATTTGTATACTGACATGTCCAAAGTGGATGGTGTGCTGTCTCTG AATGTTGGCTGTATTCAGATTGTCTATCTTCATAAATTCCTTATGTCACTTCTGAACTTCCTGAATAATTTCCAGACAGCCAAAGAGTCT CTGAGTGCTGCCACTGCCCAGGCTGCAGAAAGGGCTGCCACAAGTGTGAAAGATCTTGCCCAGAGGAGTTTTCGTGTTTCCATCAATATT GATTTGAAAGCACCGGTTATAGTCATCCCACAGTCTTCTATTTCCACCAATGCAGTAGTGGTAGATCTTGGGTTAATCAGAGTTCATAAT CAGTTCAGTCTGGTGTCTGATGAAGACTACTTAAATCCTCCAGTAATTGATAGAATGGATGTGCAGCTAACAAAGCTTACACTTTATAGG ACAGTGATCCAGCCAGGCATCTACCATCCTGATATTCAGCTGTTGCACCCAATTAACTTGGAATTTCTTGTAAATCGGAATCTAGCTGCA TCTTGGTACCACAAGGTGCCTGTTGTGGAAATTAAAGGACATCTTGATTCAATGAATGTTAGTCTAAATCAAGAAGATCTTAATCTTTTA TTTAGGATACTAACAGAAAATCTCTGTGAGGGTACTGAAGACTTGGATAAAGTGAAACCAAGAGTACAAGAGACAGGTGAAATTAAAGAG CCCCTTGAAATCTCTATATCACAAGATGTACATGATTCAAAAAATACTTTAACAACTGGAGTGGAAGAAATTAGGTCTGTAGACATCATT AATATGCTGCTGAATTTTGAAATTAAAGAGGTTGTGGTTACTTTGATGAAAAAATCAGAAAAGAAAGGAAGGCCTTTACATGAGCTAAAT GTCCTGCAACTTGGAATGGAAGCTAAAGTTAAAACCTATGACATGACTGCTAAAGCTTATCTAAAAAAAATTAGTATGCAGTGCTTTGAT TTCACTGACTCTAAAGGGGAACCTCTTCACATTATTAACTCTTCTAATGTGACTGACGAACCCCTTCTGAAAATGTTACTGACAAAGGCA GACAGTGATGGACCAGAATTTAAAACTATTCATGACAGTACCAAACAGAGACTGAAGGTTTCATTTGCATCCTTAGACTTAGTACTTCAT TTGGAAGCTTTACTTTCCTTCATGGATTTTTTATCATCTGCTGCTCCATTCTCTGAGCCTTCCTCTTCTGAGAAGGAATCCGAGCTGAAA CCACTTGTGGGGGAGTCCAGAAGTATCGCTGTCAAAGCTGTATCCAGCAACATTTCCCAAAAGGATGTGTTTGATTTAAAGATCACAGCT GAATTAAATGCATTTAATGTCTTTGTCTGTGATCAGAAGTGTAACATTGCAGATATTAAAATACATGGAATGGATGCCTCTATTTCTGTG AAGCCTAAGCAGACTGATGTGTTTGCCAGACTTAAAGATATTATAGTTATGAATGTAGATTTGCAGTCCATTCACAAAAAGGCTGTCTCT ATTTTGGGAGATGAAGTCTTTAGGTTCCAACTGACTCTTTATCCAGATGCCACAGAAGGAGAGGCCTATGCTGATATGTCCAAAGTAGAC GGCAAACTTAGTTTTAAAGTGGGTTGTATTCAGATTGTTTATGTTCATAAATTCTTCATGTCTCTTTTGAACTTCCTCAACAATTTCCAA ACTGCTAAAGAAGCTTTGAGTACAGCCACAGTCCAGGCTGCAGAAAGAGCTGCTTCCAGCATGAAAGACTTGGCTCAAAAGAGTTTCCGC CTTTTGATGGATATTAATTTGAAAGCACCAGTTATTATTATTCCTCAGTCTTCAGTATCACCTAATGCTGTTATAGCAGATCTGGGTTTA ATCAGAGTTGAAAACAAGTTTAGCTTGGTTCCTATGGAACATTATTCTCTTCCTCCAGTCATTGATAAAATGAACATCGAACTCACTCAG TTGAAGCTGTCAAGAACTATTTTGCAGGCTAGCTTGCCACAAAATGACATTGAAATTTTAAAACCAGTCAACATGCTTTTGTCCATACAG CGAAACTTAGCAGCAGCATGGTATGTGCAAATTCCAGGGATGGAGATAAAAGGAAAACTAAAACCTATGCAGGTGGCTGCAGTCCGAGAA GGGATGTCCTGGATTGTTCCTGTGCCGCTGCTGTCCCTCCTCACAGCAAAACAACTGGAGCAGATGGTGTGTGGGATGCCCGAGATCTCT GTGGAAGTCTTGAAGAAAGTGGTGCGGTACCGTGAGGTGGATGAGCAGCATCAGCTGGTGCAGTGGTTCTGGCACACGCTGGAAGAGTTC TCCAATGAGGAGCGGGTGCTTTTCATGAGGTTTGTGTCAGGAAGATCTCGACTACCAGCCAACACTGCTGACATTTCTCAGAGATTTCAA ATCATGAAGGTTGATAGGCCTTACGACAGTCTGCCTACCTCACAGACCTGCTTCTTCCAGCTGAGGCTGCCCCCGTACTCCAGCCAGCTG GTCATGGCCGAGCGCCTGCGCTATGCCATCAACAACTGCCGCTCAATCGACATGGACAACTACATGCTCTCGAGAAACGTGGACAACGCC >In-frame_VPS13C_ENST00000261517_chr15_62232846_-_HERC1_ENST00000443617_chr15_63904755_-_6093nt ATGGTGCTGGAGTCGGTGGTCGCGGACTTGCTGAACCGCTTCCTGGGGGACTATGTGGAGAACCTGAACAAGTCCCAGCTGAAGCTGGGC ATCTGGGGCGGAAATGTGGCTTTAGATAATCTACAGATAAAAGAAAATGCCCTGAGTGAATTGGATGTTCCTTTTAAAGTCAAGGCTGGC CAAATTGATAAATTAACTTTGAAGATTCCTTGGAAGAACCTTTATGGAGAAGCAGTTGTTGCGACCCTGGAAGGATTATACCTGCTTGTT GTCCCTGGAGCAAGTATTAAGTATGATGCTGTAAAAGAAGAAAAATCCTTGCAGGATGTTAAACAGAAAGAGCTATCCCGAATTGAAGAA GCCCTTCAAAAAGCAGCAGAAAAAGGCACACATTCAGGGGAGTTCATATATGGCTTGGAGAACTTTGTTTACAAGGACATCAAGCCTGGA CGTAAACGTAAAAAGCACAAAAAACATTTTAAGAAACCTTTTAAAGGTCTTGATCGTTCAAAAGATAAGCCAAAAGAAGCCAAAAAGGAT ACATTTGTGGAAAAATTGGCAACTCAAGTAATAAAAAATGTACAAGTAAAAATCACAGATATTCACATTAAATATGAAGATGATGTCACT GATCCAAAGCGGCCTCTTTCATTTGGTGTCACACTGGGAGAGCTTAGTCTACTGACTGCAAATGAACACTGGACTCCATGCATATTAAAT GAAGCAGACAAAATTATATACAAGCTTATACGACTTGATAGTCTTAGCGCCTACTGGAATGTAAATTGCAGCATGTCTTACCAGAGATCA AGGGAACAGATTTTGGATCAGCTGAAAAATGAAATTCTTACAAGTGGAAATATACCCCCAAATTATCAATACATTTTCCAGCCAATATCA GCCTCTGCAAAACTCTACATGAATCCTTATGCAGAATCAGAGCTCAAAACGCCCAAACTGGATTGCAACATAGAAATACAAAATATTGCC ATTGAACTGACCAAACCTCAGTACTTAAGTATGATTGACCTTTTGGAGTCAGTGGATTATATGGTTAGGAATGCGCCTTATAGGAAATAC AAGCCTTATTTACCACTTCATACCAATGGTCGACGATGGTGGAAATATGCAATTGATTCTGTTCTTGAAGTTCATATAAGAAGGTATACA CAGATGTGGTCATGGAGTAACATAAAAAAGCACAGGCAGTTACTCAAGAGTTATAAAATTGCCTACAAAAACAAGTTAACACAGTCTAAA GTCTCAGAAGAAATACAGAAAGAAATTCAGGACTTGGAGAAGACTCTAGATGTTTTTAACATAATTTTAGCAAGGCAACAAGCACAAGTT GAGGTGATTCGGTCTGGGCAAAAATTAAGGAAAAAGTCTGCTGACACAGGCGAGAAACGTGGAGGCTGGTTTAGTGGGTTGTGGGGTAAG AAAGAGTCTAAGAAAAAGGACGAAGAATCATTGATTCCTGAAACTATTGATGACCTTATGACTCCAGAGGAAAAAGATAAACTCTTCACT GCCATTGGTTATAGTGAGAGTACCCACAACCTAACTTTACCTAAGCAGTATGTTGCCCATATTATGACCCTGAAGTTAGTAAGCACCTCT GTTACGATAAGAGAAAACAAGAATATTCCAGAAATACTAAAAATTCAGATAATTGGCCTGGGCACTCAAGTATCTCAGCGACCAGGAGCA CAAGCACTTAAGGTAGAAGCGAAATTAGAACACTGGTATATAACAGGTTTGAGACAGCAGGATATTGTGCCATCACTTGTGGCTTCAATT GGTGACACTACATCATCCTTGCTTAAAATTAAATTTGAAACCAATCCGGAGGATAGTCCTGCTGACCAGACTCTGATTGTTCAGTCCCAG CCTGTGGAGGTCATCTATGATGCTAAAACTGTCAATGCAGTGGTTGAATTCTTTCAATCAAATAAGGGATTGGATCTTGAGCAAATAACA TCAGCAACATTGATGAAGCTGGAAGAAATTAAGGAGAGAACAGCTACAGGACTTACACATATTATTGAAACTCGAAAAGTCCTTGATTTA AGGATAAATCTGAAGCCTTCTTATCTAGTAGTTCCACAGACGGGTTTCCACCATGAAAAGTCAGATCTTCTGATTTTAGATTTTGGTACA TTTCAGCTCAACAGTAAAGATCAAGGTTTACAGAAGACTACTAATTCATCTCTGGAAGAAATAATGGATAAGGCATATGACAAGTTTGAT GTTGAAATAAAAAATGTACAACTACTTTTTGCAAGAGCAGAGGAAACCTGGAAAAAGTGTCGATTTCAGCATCCATCAACTATGCATATA TTGCAACCCATGGATATTCATGTTGAGTTGGCTAAGGCCATGGTAGAAAAAGACATTAGAATGGCCAGATTTAAAGTGTCAGGAGGACTT CCTTTGATGCATGTGAGAATTTCTGACCAGAAGATGAAAGATGTGCTATATTTGATGAACAGTATACCTTTGCCACAGAAATCATCAGCC CAGTCTCCAGAGAGACAGGTATCCTCAATTCCTATTATTTCAGGTGGTACAAAAGGTCTACTTGGTACTTCACTATTGCTAGACACTGTG GAATCAGAGTCTGATGATGAGTATTTTGATGCTGAAGATGGAGAACCACAGACTTGTAAAAGTATGAAAGGATCAGAACTTAAAAAAGCT GCAGAGGTCCCAAATGAGGAGCTCATCAATCTTCTACTCAAGTTTGAAATTAAAGAAGTGATTTTGGAATTTACTAAACAGCAGAAAGAA GAAGATACAATTCTAGTATTTAATGTTACTCAGTTAGGAACAGAGGCCACAATGAGAACATTTGACTTAACTGTGGTATCTTATTTAAAG AAAATCAGCTTGGATTATCATGAAATTGAAGGATCCAAAAGGAAGCCCCTTCACTTGATTAGCTCTTCTGACAAACCTGGATTAGATCTT TTGAAAGTGGAGTATATTAAGGCTGATAAGAATGGACCTAGTTTTCAAACTGCTTTTGGAAAAACTGAACAAACAGTTAAGGTGGCCTTT TCATCTTTAAATCTGTTGCTGCAAACACAAGCTCTTGTCGCTTCTATTAATTACCTCACAACCATTATTCCATCTGATGATCAAAGCATA AGTGTTGCTAAGGAGGTACAAATTTCAACTGAAAAACAACAAAAAAATTCAACTCTGCCAAAAGCGATTGTATCCTCCAGAGATAGTGAC ATTATTGATTTCAGGCTATTTGCCAAGTTGAATGCTTTCTGTGTCATTGTTTGCAACGAAAAGAACAATATCGCCGAAATCAAGATTCAA GGACTGGATTCCTCCCTTTCTCTCCAGTCAAGAAAGCAGTCACTTTTTGCCCGACTAGAAAATATTATTGTCACAGATGTTGATCCAAAG ACAGTTCATAAGAAAGCTGTGTCAATAATGGGAAATGAAGTTTTCCGTTTTAATTTGGATTTGTATCCAGATGCTACTGAGGGGGATTTG TATACTGACATGTCCAAAGTGGATGGTGTGCTGTCTCTGAATGTTGGCTGTATTCAGATTGTCTATCTTCATAAATTCCTTATGTCACTT CTGAACTTCCTGAATAATTTCCAGACAGCCAAAGAGTCTCTGAGTGCTGCCACTGCCCAGGCTGCAGAAAGGGCTGCCACAAGTGTGAAA GATCTTGCCCAGAGGAGTTTTCGTGTTTCCATCAATATTGATTTGAAAGCACCGGTTATAGTCATCCCACAGTCTTCTATTTCCACCAAT GCAGTAGTGGTAGATCTTGGGTTAATCAGAGTTCATAATCAGTTCAGTCTGGTGTCTGATGAAGACTACTTAAATCCTCCAGTAATTGAT AGAATGGATGTGCAGCTAACAAAGCTTACACTTTATAGGACAGTGATCCAGCCAGGCATCTACCATCCTGATATTCAGCTGTTGCACCCA ATTAACTTGGAATTTCTTGTAAATCGGAATCTAGCTGCATCTTGGTACCACAAGGTGCCTGTTGTGGAAATTAAAGGACATCTTGATTCA ATGAATGTTAGTCTAAATCAAGAAGATCTTAATCTTTTATTTAGGATACTAACAGAAAATCTCTGTGAGGGTACTGAAGACTTGGATAAA GTGAAACCAAGAGTACAAGAGACAGGTGAAATTAAAGAGCCCCTTGAAATCTCTATATCACAAGATGTACATGATTCAAAAAATACTTTA ACAACTGGAGTGGAAGAAATTAGGTCTGTAGACATCATTAATATGCTGCTGAATTTTGAAATTAAAGAGGTTGTGGTTACTTTGATGAAA AAATCAGAAAAGAAAGGAAGGCCTTTACATGAGCTAAATGTCCTGCAACTTGGAATGGAAGCTAAAGTTAAAACCTATGACATGACTGCT AAAGCTTATCTAAAAAAAATTAGTATGCAGTGCTTTGATTTCACTGACTCTAAAGGGGAACCTCTTCACATTATTAACTCTTCTAATGTG ACTGACGAACCCCTTCTGAAAATGTTACTGACAAAGGCAGACAGTGATGGACCAGAATTTAAAACTATTCATGACAGTACCAAACAGAGA CTGAAGGTTTCATTTGCATCCTTAGACTTAGTACTTCATTTGGAAGCTTTACTTTCCTTCATGGATTTTTTATCATCTGCTGCTCCATTC TCTGAGCCTTCCTCTTCTGAGAAGGAATCCGAGCTGAAACCACTTGTGGGGGAGTCCAGAAGTATCGCTGTCAAAGCTGTATCCAGCAAC ATTTCCCAAAAGGATGTGTTTGATTTAAAGATCACAGCTGAATTAAATGCATTTAATGTCTTTGTCTGTGATCAGAAGTGTAACATTGCA GATATTAAAATACATGGAATGGATGCCTCTATTTCTGTGAAGCCTAAGCAGACTGATGTGTTTGCCAGACTTAAAGATATTATAGTTATG AATGTAGATTTGCAGTCCATTCACAAAAAGGCTGTCTCTATTTTGGGAGATGAAGTCTTTAGGTTCCAACTGACTCTTTATCCAGATGCC ACAGAAGGAGAGGCCTATGCTGATATGTCCAAAGTAGACGGCAAACTTAGTTTTAAAGTGGGTTGTATTCAGATTGTTTATGTTCATAAA TTCTTCATGTCTCTTTTGAACTTCCTCAACAATTTCCAAACTGCTAAAGAAGCTTTGAGTACAGCCACAGTCCAGGCTGCAGAAAGAGCT GCTTCCAGCATGAAAGACTTGGCTCAAAAGAGTTTCCGCCTTTTGATGGATATTAATTTGAAAGCACCAGTTATTATTATTCCTCAGTCT TCAGTATCACCTAATGCTGTTATAGCAGATCTGGGTTTAATCAGAGTTGAAAACAAGTTTAGCTTGGTTCCTATGGAACATTATTCTCTT CCTCCAGTCATTGATAAAATGAACATCGAACTCACTCAGTTGAAGCTGTCAAGAACTATTTTGCAGGCTAGCTTGCCACAAAATGACATT GAAATTTTAAAACCAGTCAACATGCTTTTGTCCATACAGCGAAACTTAGCAGCAGCATGGTATGTGCAAATTCCAGGGATGGAGATAAAA GGAAAACTAAAACCTATGCAGGTGGCTGCAGTCCGAGAAGGGATGTCCTGGATTGTTCCTGTGCCGCTGCTGTCCCTCCTCACAGCAAAA CAACTGGAGCAGATGGTGTGTGGGATGCCCGAGATCTCTGTGGAAGTCTTGAAGAAAGTGGTGCGGTACCGTGAGGTGGATGAGCAGCAT CAGCTGGTGCAGTGGTTCTGGCACACGCTGGAAGAGTTCTCCAATGAGGAGCGGGTGCTTTTCATGAGGTTTGTGTCAGGAAGATCTCGA CTACCAGCCAACACTGCTGACATTTCTCAGAGATTTCAAATCATGAAGGTTGATAGGCCTTACGACAGTCTGCCTACCTCACAGACCTGC TTCTTCCAGCTGAGGCTGCCCCCGTACTCCAGCCAGCTGGTCATGGCCGAGCGCCTGCGCTATGCCATCAACAACTGCCGCTCAATCGAC >In-frame_VPS13C_ENST00000395896_chr15_62232846_-_HERC1_ENST00000443617_chr15_63904755_-_6093nt ATGGTGCTGGAGTCGGTGGTCGCGGACTTGCTGAACCGCTTCCTGGGGGACTATGTGGAGAACCTGAACAAGTCCCAGCTGAAGCTGGGC ATCTGGGGCGGAAATGTGGCTTTAGATAATCTACAGATAAAAGAAAATGCCCTGAGTGAATTGGATGTTCCTTTTAAAGTCAAGGCTGGC CAAATTGATAAATTAACTTTGAAGATTCCTTGGAAGAACCTTTATGGAGAAGCAGTTGTTGCGACCCTGGAAGGATTATACCTGCTTGTT GTCCCTGGAGCAAGTATTAAGTATGATGCTGTAAAAGAAGAAAAATCCTTGCAGGATGTTAAACAGAAAGAGCTATCCCGAATTGAAGAA GCCCTTCAAAAAGCAGCAGAAAAAGGCACACATTCAGGGGAGTTCATATATGGCTTGGAGAACTTTGTTTACAAGGACATCAAGCCTGGA CGTAAACGTAAAAAGCACAAAAAACATTTTAAGAAACCTTTTAAAGGTCTTGATCGTTCAAAAGATAAGCCAAAAGAAGCCAAAAAGGAT ACATTTGTGGAAAAATTGGCAACTCAAGTAATAAAAAATGTACAAGTAAAAATCACAGATATTCACATTAAATATGAAGATGATGTCACT GATCCAAAGCGGCCTCTTTCATTTGGTGTCACACTGGGAGAGCTTAGTCTACTGACTGCAAATGAACACTGGACTCCATGCATATTAAAT GAAGCAGACAAAATTATATACAAGCTTATACGACTTGATAGTCTTAGCGCCTACTGGAATGTAAATTGCAGCATGTCTTACCAGAGATCA AGGGAACAGATTTTGGATCAGCTGAAAAATGAAATTCTTACAAGTGGAAATATACCCCCAAATTATCAATACATTTTCCAGCCAATATCA GCCTCTGCAAAACTCTACATGAATCCTTATGCAGAATCAGAGCTCAAAACGCCCAAACTGGATTGCAACATAGAAATACAAAATATTGCC ATTGAACTGACCAAACCTCAGTACTTAAGTATGATTGACCTTTTGGAGTCAGTGGATTATATGGTTAGGAATGCGCCTTATAGGAAATAC AAGCCTTATTTACCACTTCATACCAATGGTCGACGATGGTGGAAATATGCAATTGATTCTGTTCTTGAAGTTCATATAAGAAGGTATACA CAGATGTGGTCATGGAGTAACATAAAAAAGCACAGGCAGTTACTCAAGAGTTATAAAATTGCCTACAAAAACAAGTTAACACAGTCTAAA GTCTCAGAAGAAATACAGAAAGAAATTCAGGACTTGGAGAAGACTCTAGATGTTTTTAACATAATTTTAGCAAGGCAACAAGCACAAGTT GAGGTGATTCGGTCTGGGCAAAAATTAAGGAAAAAGTCTGCTGACACAGGCGAGAAACGTGGAGGCTGGTTTAGTGGGTTGTGGGGTAAG AAAGAGTCTAAGAAAAAGGACGAAGAATCATTGATTCCTGAAACTATTGATGACCTTATGACTCCAGAGGAAAAAGATAAACTCTTCACT GCCATTGGTTATAGTGAGAGTACCCACAACCTAACTTTACCTAAGCAGTATGTTGCCCATATTATGACCCTGAAGTTAGTAAGCACCTCT GTTACGATAAGAGAAAACAAGAATATTCCAGAAATACTAAAAATTCAGATAATTGGCCTGGGCACTCAAGTATCTCAGCGACCAGGAGCA CAAGCACTTAAGGTAGAAGCGAAATTAGAACACTGGTATATAACAGGTTTGAGACAGCAGGATATTGTGCCATCACTTGTGGCTTCAATT GGTGACACTACATCATCCTTGCTTAAAATTAAATTTGAAACCAATCCGGAGGATAGTCCTGCTGACCAGACTCTGATTGTTCAGTCCCAG CCTGTGGAGGTCATCTATGATGCTAAAACTGTCAATGCAGTGGTTGAATTCTTTCAATCAAATAAGGGATTGGATCTTGAGCAAATAACA TCAGCAACATTGATGAAGCTGGAAGAAATTAAGGAGAGAACAGCTACAGGACTTACACATATTATTGAAACTCGAAAAGTCCTTGATTTA AGGATAAATCTGAAGCCTTCTTATCTAGTAGTTCCACAGACGGGTTTCCACCATGAAAAGTCAGATCTTCTGATTTTAGATTTTGGTACA TTTCAGCTCAACAGTAAAGATCAAGGTTTACAGAAGACTACTAATTCATCTCTGGAAGAAATAATGGATAAGGCATATGACAAGTTTGAT GTTGAAATAAAAAATGTACAACTACTTTTTGCAAGAGCAGAGGAAACCTGGAAAAAGTGTCGATTTCAGCATCCATCAACTATGCATATA TTGCAACCCATGGATATTCATGTTGAGTTGGCTAAGGCCATGGTAGAAAAAGACATTAGAATGGCCAGATTTAAAGTGTCAGGAGGACTT CCTTTGATGCATGTGAGAATTTCTGACCAGAAGATGAAAGATGTGCTATATTTGATGAACAGTATACCTTTGCCACAGAAATCATCAGCC CAGTCTCCAGAGAGACAGGTATCCTCAATTCCTATTATTTCAGGTGGTACAAAAGGTCTACTTGGTACTTCACTATTGCTAGACACTGTG GAATCAGAGTCTGATGATGAGTATTTTGATGCTGAAGATGGAGAACCACAGACTTGTAAAAGTATGAAAGGATCAGAACTTAAAAAAGCT GCAGAGGTCCCAAATGAGGAGCTCATCAATCTTCTACTCAAGTTTGAAATTAAAGAAGTGATTTTGGAATTTACTAAACAGCAGAAAGAA GAAGATACAATTCTAGTATTTAATGTTACTCAGTTAGGAACAGAGGCCACAATGAGAACATTTGACTTAACTGTGGTATCTTATTTAAAG AAAATCAGCTTGGATTATCATGAAATTGAAGGATCCAAAAGGAAGCCCCTTCACTTGATTAGCTCTTCTGACAAACCTGGATTAGATCTT TTGAAAGTGGAGTATATTAAGGCTGATAAGAATGGACCTAGTTTTCAAACTGCTTTTGGAAAAACTGAACAAACAGTTAAGGTGGCCTTT TCATCTTTAAATCTGTTGCTGCAAACACAAGCTCTTGTCGCTTCTATTAATTACCTCACAACCATTATTCCATCTGATGATCAAAGCATA AGTGTTGCTAAGGAGGTACAAATTTCAACTGAAAAACAACAAAAAAATTCAACTCTGCCAAAAGCGATTGTATCCTCCAGAGATAGTGAC ATTATTGATTTCAGGCTATTTGCCAAGTTGAATGCTTTCTGTGTCATTGTTTGCAACGAAAAGAACAATATCGCCGAAATCAAGATTCAA GGACTGGATTCCTCCCTTTCTCTCCAGTCAAGAAAGCAGTCACTTTTTGCCCGACTAGAAAATATTATTGTCACAGATGTTGATCCAAAG ACAGTTCATAAGAAAGCTGTGTCAATAATGGGAAATGAAGTTTTCCGTTTTAATTTGGATTTGTATCCAGATGCTACTGAGGGGGATTTG TATACTGACATGTCCAAAGTGGATGGTGTGCTGTCTCTGAATGTTGGCTGTATTCAGATTGTCTATCTTCATAAATTCCTTATGTCACTT CTGAACTTCCTGAATAATTTCCAGACAGCCAAAGAGTCTCTGAGTGCTGCCACTGCCCAGGCTGCAGAAAGGGCTGCCACAAGTGTGAAA GATCTTGCCCAGAGGAGTTTTCGTGTTTCCATCAATATTGATTTGAAAGCACCGGTTATAGTCATCCCACAGTCTTCTATTTCCACCAAT GCAGTAGTGGTAGATCTTGGGTTAATCAGAGTTCATAATCAGTTCAGTCTGGTGTCTGATGAAGACTACTTAAATCCTCCAGTAATTGAT AGAATGGATGTGCAGCTAACAAAGCTTACACTTTATAGGACAGTGATCCAGCCAGGCATCTACCATCCTGATATTCAGCTGTTGCACCCA ATTAACTTGGAATTTCTTGTAAATCGGAATCTAGCTGCATCTTGGTACCACAAGGTGCCTGTTGTGGAAATTAAAGGACATCTTGATTCA ATGAATGTTAGTCTAAATCAAGAAGATCTTAATCTTTTATTTAGGATACTAACAGAAAATCTCTGTGAGGGTACTGAAGACTTGGATAAA GTGAAACCAAGAGTACAAGAGACAGGTGAAATTAAAGAGCCCCTTGAAATCTCTATATCACAAGATGTACATGATTCAAAAAATACTTTA ACAACTGGAGTGGAAGAAATTAGGTCTGTAGACATCATTAATATGCTGCTGAATTTTGAAATTAAAGAGGTTGTGGTTACTTTGATGAAA AAATCAGAAAAGAAAGGAAGGCCTTTACATGAGCTAAATGTCCTGCAACTTGGAATGGAAGCTAAAGTTAAAACCTATGACATGACTGCT AAAGCTTATCTAAAAAAAATTAGTATGCAGTGCTTTGATTTCACTGACTCTAAAGGGGAACCTCTTCACATTATTAACTCTTCTAATGTG ACTGACGAACCCCTTCTGAAAATGTTACTGACAAAGGCAGACAGTGATGGACCAGAATTTAAAACTATTCATGACAGTACCAAACAGAGA CTGAAGGTTTCATTTGCATCCTTAGACTTAGTACTTCATTTGGAAGCTTTACTTTCCTTCATGGATTTTTTATCATCTGCTGCTCCATTC TCTGAGCCTTCCTCTTCTGAGAAGGAATCCGAGCTGAAACCACTTGTGGGGGAGTCCAGAAGTATCGCTGTCAAAGCTGTATCCAGCAAC ATTTCCCAAAAGGATGTGTTTGATTTAAAGATCACAGCTGAATTAAATGCATTTAATGTCTTTGTCTGTGATCAGAAGTGTAACATTGCA GATATTAAAATACATGGAATGGATGCCTCTATTTCTGTGAAGCCTAAGCAGACTGATGTGTTTGCCAGACTTAAAGATATTATAGTTATG AATGTAGATTTGCAGTCCATTCACAAAAAGGCTGTCTCTATTTTGGGAGATGAAGTCTTTAGGTTCCAACTGACTCTTTATCCAGATGCC ACAGAAGGAGAGGCCTATGCTGATATGTCCAAAGTAGACGGCAAACTTAGTTTTAAAGTGGGTTGTATTCAGATTGTTTATGTTCATAAA TTCTTCATGTCTCTTTTGAACTTCCTCAACAATTTCCAAACTGCTAAAGAAGCTTTGAGTACAGCCACAGTCCAGGCTGCAGAAAGAGCT GCTTCCAGCATGAAAGACTTGGCTCAAAAGAGTTTCCGCCTTTTGATGGATATTAATTTGAAAGCACCAGTTATTATTATTCCTCAGTCT TCAGTATCACCTAATGCTGTTATAGCAGATCTGGGTTTAATCAGAGTTGAAAACAAGTTTAGCTTGGTTCCTATGGAACATTATTCTCTT CCTCCAGTCATTGATAAAATGAACATCGAACTCACTCAGTTGAAGCTGTCAAGAACTATTTTGCAGGCTAGCTTGCCACAAAATGACATT GAAATTTTAAAACCAGTCAACATGCTTTTGTCCATACAGCGAAACTTAGCAGCAGCATGGTATGTGCAAATTCCAGGGATGGAGATAAAA GGAAAACTAAAACCTATGCAGGTGGCTGCAGTCCGAGAAGGGATGTCCTGGATTGTTCCTGTGCCGCTGCTGTCCCTCCTCACAGCAAAA CAACTGGAGCAGATGGTGTGTGGGATGCCCGAGATCTCTGTGGAAGTCTTGAAGAAAGTGGTGCGGTACCGTGAGGTGGATGAGCAGCAT CAGCTGGTGCAGTGGTTCTGGCACACGCTGGAAGAGTTCTCCAATGAGGAGCGGGTGCTTTTCATGAGGTTTGTGTCAGGAAGATCTCGA CTACCAGCCAACACTGCTGACATTTCTCAGAGATTTCAAATCATGAAGGTTGATAGGCCTTACGACAGTCTGCCTACCTCACAGACCTGC TTCTTCCAGCTGAGGCTGCCCCCGTACTCCAGCCAGCTGGTCATGGCCGAGCGCCTGCGCTATGCCATCAACAACTGCCGCTCAATCGAC >In-frame_VPS13C_ENST00000395898_chr15_62232846_-_HERC1_ENST00000443617_chr15_63904755_-_5964nt ATGGTGCTGGAGTCGGTGGTCGCGGACTTGCTGAACCGCTTCCTGGGGGACTATGTGGAGAACCTGAACAAGTCCCAGCTGAAGCTGGGC ATCTGGGGCGGAAATGTGGCTTTAGATAATCTACAGATAAAAGAAAATGCCCTGAGTGAATTGGATGTTCCTTTTAAAGTCAAGGCTGGC CAAATTGATAAATTAACTTTGAAGATTCCTTGGAAGAACCTTTATGGAGAAGCAGTTGTTGCGACCCTGGAAGGATTATACCTGCTTGTT GTCCCTGGAGCAAGTATTAAGTATGATGCTGTAAAAGAAGAAAAATCCTTGCAGGATGTTAAACAGAAAGAGCTATCCCGAATTGAAGAA GCCCTTCAAAAAGCAGCAGAAAAAGATAAGCCAAAAGAAGCCAAAAAGGATACATTTGTGGAAAAATTGGCAACTCAAGTAATAAAAAAT GTACAAGTAAAAATCACAGATATTCACATTAAATATGAAGATGATGTCACTGATCCAAAGCGGCCTCTTTCATTTGGTGTCACACTGGGA GAGCTTAGTCTACTGACTGCAAATGAACACTGGACTCCATGCATATTAAATGAAGCAGACAAAATTATATACAAGCTTATACGACTTGAT AGTCTTAGCGCCTACTGGAATGTAAATTGCAGCATGTCTTACCAGAGATCAAGGGAACAGATTTTGGATCAGCTGAAAAATGAAATTCTT ACAAGTGGAAATATACCCCCAAATTATCAATACATTTTCCAGCCAATATCAGCCTCTGCAAAACTCTACATGAATCCTTATGCAGAATCA GAGCTCAAAACGCCCAAACTGGATTGCAACATAGAAATACAAAATATTGCCATTGAACTGACCAAACCTCAGTACTTAAGTATGATTGAC CTTTTGGAGTCAGTGGATTATATGGTTAGGAATGCGCCTTATAGGAAATACAAGCCTTATTTACCACTTCATACCAATGGTCGACGATGG TGGAAATATGCAATTGATTCTGTTCTTGAAGTTCATATAAGAAGGTATACACAGATGTGGTCATGGAGTAACATAAAAAAGCACAGGCAG TTACTCAAGAGTTATAAAATTGCCTACAAAAACAAGTTAACACAGTCTAAAGTCTCAGAAGAAATACAGAAAGAAATTCAGGACTTGGAG AAGACTCTAGATGTTTTTAACATAATTTTAGCAAGGCAACAAGCACAAGTTGAGGTGATTCGGTCTGGGCAAAAATTAAGGAAAAAGTCT GCTGACACAGGCGAGAAACGTGGAGGCTGGTTTAGTGGGTTGTGGGGTAAGAAAGAGTCTAAGAAAAAGGACGAAGAATCATTGATTCCT GAAACTATTGATGACCTTATGACTCCAGAGGAAAAAGATAAACTCTTCACTGCCATTGGTTATAGTGAGAGTACCCACAACCTAACTTTA CCTAAGCAGTATGTTGCCCATATTATGACCCTGAAGTTAGTAAGCACCTCTGTTACGATAAGAGAAAACAAGAATATTCCAGAAATACTA AAAATTCAGATAATTGGCCTGGGCACTCAAGTATCTCAGCGACCAGGAGCACAAGCACTTAAGGTAGAAGCGAAATTAGAACACTGGTAT ATAACAGGTTTGAGACAGCAGGATATTGTGCCATCACTTGTGGCTTCAATTGGTGACACTACATCATCCTTGCTTAAAATTAAATTTGAA ACCAATCCGGAGGATAGTCCTGCTGACCAGACTCTGATTGTTCAGTCCCAGCCTGTGGAGGTCATCTATGATGCTAAAACTGTCAATGCA GTGGTTGAATTCTTTCAATCAAATAAGGGATTGGATCTTGAGCAAATAACATCAGCAACATTGATGAAGCTGGAAGAAATTAAGGAGAGA ACAGCTACAGGACTTACACATATTATTGAAACTCGAAAAGTCCTTGATTTAAGGATAAATCTGAAGCCTTCTTATCTAGTAGTTCCACAG ACGGGTTTCCACCATGAAAAGTCAGATCTTCTGATTTTAGATTTTGGTACATTTCAGCTCAACAGTAAAGATCAAGGTTTACAGAAGACT ACTAATTCATCTCTGGAAGAAATAATGGATAAGGCATATGACAAGTTTGATGTTGAAATAAAAAATGTACAACTACTTTTTGCAAGAGCA GAGGAAACCTGGAAAAAGTGTCGATTTCAGCATCCATCAACTATGCATATATTGCAACCCATGGATATTCATGTTGAGTTGGCTAAGGCC ATGGTAGAAAAAGACATTAGAATGGCCAGATTTAAAGTGTCAGGAGGACTTCCTTTGATGCATGTGAGAATTTCTGACCAGAAGATGAAA GATGTGCTATATTTGATGAACAGTATACCTTTGCCACAGAAATCATCAGCCCAGTCTCCAGAGAGACAGGTATCCTCAATTCCTATTATT TCAGGTGGTACAAAAGGTCTACTTGGTACTTCACTATTGCTAGACACTGTGGAATCAGAGTCTGATGATGAGTATTTTGATGCTGAAGAT GGAGAACCACAGACTTGTAAAAGTATGAAAGGATCAGAACTTAAAAAAGCTGCAGAGGTCCCAAATGAGGAGCTCATCAATCTTCTACTC AAGTTTGAAATTAAAGAAGTGATTTTGGAATTTACTAAACAGCAGAAAGAAGAAGATACAATTCTAGTATTTAATGTTACTCAGTTAGGA ACAGAGGCCACAATGAGAACATTTGACTTAACTGTGGTATCTTATTTAAAGAAAATCAGCTTGGATTATCATGAAATTGAAGGATCCAAA AGGAAGCCCCTTCACTTGATTAGCTCTTCTGACAAACCTGGATTAGATCTTTTGAAAGTGGAGTATATTAAGGCTGATAAGAATGGACCT AGTTTTCAAACTGCTTTTGGAAAAACTGAACAAACAGTTAAGGTGGCCTTTTCATCTTTAAATCTGTTGCTGCAAACACAAGCTCTTGTC GCTTCTATTAATTACCTCACAACCATTATTCCATCTGATGATCAAAGCATAAGTGTTGCTAAGGAGGTACAAATTTCAACTGAAAAACAA CAAAAAAATTCAACTCTGCCAAAAGCGATTGTATCCTCCAGAGATAGTGACATTATTGATTTCAGGCTATTTGCCAAGTTGAATGCTTTC TGTGTCATTGTTTGCAACGAAAAGAACAATATCGCCGAAATCAAGATTCAAGGACTGGATTCCTCCCTTTCTCTCCAGTCAAGAAAGCAG TCACTTTTTGCCCGACTAGAAAATATTATTGTCACAGATGTTGATCCAAAGACAGTTCATAAGAAAGCTGTGTCAATAATGGGAAATGAA GTTTTCCGTTTTAATTTGGATTTGTATCCAGATGCTACTGAGGGGGATTTGTATACTGACATGTCCAAAGTGGATGGTGTGCTGTCTCTG AATGTTGGCTGTATTCAGATTGTCTATCTTCATAAATTCCTTATGTCACTTCTGAACTTCCTGAATAATTTCCAGACAGCCAAAGAGTCT CTGAGTGCTGCCACTGCCCAGGCTGCAGAAAGGGCTGCCACAAGTGTGAAAGATCTTGCCCAGAGGAGTTTTCGTGTTTCCATCAATATT GATTTGAAAGCACCGGTTATAGTCATCCCACAGTCTTCTATTTCCACCAATGCAGTAGTGGTAGATCTTGGGTTAATCAGAGTTCATAAT CAGTTCAGTCTGGTGTCTGATGAAGACTACTTAAATCCTCCAGTAATTGATAGAATGGATGTGCAGCTAACAAAGCTTACACTTTATAGG ACAGTGATCCAGCCAGGCATCTACCATCCTGATATTCAGCTGTTGCACCCAATTAACTTGGAATTTCTTGTAAATCGGAATCTAGCTGCA TCTTGGTACCACAAGGTGCCTGTTGTGGAAATTAAAGGACATCTTGATTCAATGAATGTTAGTCTAAATCAAGAAGATCTTAATCTTTTA TTTAGGATACTAACAGAAAATCTCTGTGAGGGTACTGAAGACTTGGATAAAGTGAAACCAAGAGTACAAGAGACAGGTGAAATTAAAGAG CCCCTTGAAATCTCTATATCACAAGATGTACATGATTCAAAAAATACTTTAACAACTGGAGTGGAAGAAATTAGGTCTGTAGACATCATT AATATGCTGCTGAATTTTGAAATTAAAGAGGTTGTGGTTACTTTGATGAAAAAATCAGAAAAGAAAGGAAGGCCTTTACATGAGCTAAAT GTCCTGCAACTTGGAATGGAAGCTAAAGTTAAAACCTATGACATGACTGCTAAAGCTTATCTAAAAAAAATTAGTATGCAGTGCTTTGAT TTCACTGACTCTAAAGGGGAACCTCTTCACATTATTAACTCTTCTAATGTGACTGACGAACCCCTTCTGAAAATGTTACTGACAAAGGCA GACAGTGATGGACCAGAATTTAAAACTATTCATGACAGTACCAAACAGAGACTGAAGGTTTCATTTGCATCCTTAGACTTAGTACTTCAT TTGGAAGCTTTACTTTCCTTCATGGATTTTTTATCATCTGCTGCTCCATTCTCTGAGCCTTCCTCTTCTGAGAAGGAATCCGAGCTGAAA CCACTTGTGGGGGAGTCCAGAAGTATCGCTGTCAAAGCTGTATCCAGCAACATTTCCCAAAAGGATGTGTTTGATTTAAAGATCACAGCT GAATTAAATGCATTTAATGTCTTTGTCTGTGATCAGAAGTGTAACATTGCAGATATTAAAATACATGGAATGGATGCCTCTATTTCTGTG AAGCCTAAGCAGACTGATGTGTTTGCCAGACTTAAAGATATTATAGTTATGAATGTAGATTTGCAGTCCATTCACAAAAAGGCTGTCTCT ATTTTGGGAGATGAAGTCTTTAGGTTCCAACTGACTCTTTATCCAGATGCCACAGAAGGAGAGGCCTATGCTGATATGTCCAAAGTAGAC GGCAAACTTAGTTTTAAAGTGGGTTGTATTCAGATTGTTTATGTTCATAAATTCTTCATGTCTCTTTTGAACTTCCTCAACAATTTCCAA ACTGCTAAAGAAGCTTTGAGTACAGCCACAGTCCAGGCTGCAGAAAGAGCTGCTTCCAGCATGAAAGACTTGGCTCAAAAGAGTTTCCGC CTTTTGATGGATATTAATTTGAAAGCACCAGTTATTATTATTCCTCAGTCTTCAGTATCACCTAATGCTGTTATAGCAGATCTGGGTTTA ATCAGAGTTGAAAACAAGTTTAGCTTGGTTCCTATGGAACATTATTCTCTTCCTCCAGTCATTGATAAAATGAACATCGAACTCACTCAG TTGAAGCTGTCAAGAACTATTTTGCAGGCTAGCTTGCCACAAAATGACATTGAAATTTTAAAACCAGTCAACATGCTTTTGTCCATACAG CGAAACTTAGCAGCAGCATGGTATGTGCAAATTCCAGGGATGGAGATAAAAGGAAAACTAAAACCTATGCAGGTGGCTGCAGTCCGAGAA GGGATGTCCTGGATTGTTCCTGTGCCGCTGCTGTCCCTCCTCACAGCAAAACAACTGGAGCAGATGGTGTGTGGGATGCCCGAGATCTCT GTGGAAGTCTTGAAGAAAGTGGTGCGGTACCGTGAGGTGGATGAGCAGCATCAGCTGGTGCAGTGGTTCTGGCACACGCTGGAAGAGTTC TCCAATGAGGAGCGGGTGCTTTTCATGAGGTTTGTGTCAGGAAGATCTCGACTACCAGCCAACACTGCTGACATTTCTCAGAGATTTCAA ATCATGAAGGTTGATAGGCCTTACGACAGTCTGCCTACCTCACAGACCTGCTTCTTCCAGCTGAGGCTGCCCCCGTACTCCAGCCAGCTG GTCATGGCCGAGCGCCTGCGCTATGCCATCAACAACTGCCGCTCAATCGACATGGACAACTACATGCTCTCGAGAAACGTGGACAACGCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_VPS13C_ENST00000249837_chr15_62232846_-_HERC1_ENST00000443617_chr15_63904755_-_6526nt GGCCTGCGCCGGAGGGGCTGTCATTTGCAGCGCTGGTCGCAGCCCTCAGCTGCGCCGGGCGGTTCCGGCTCCTCCCTCTCCTTGTGCCTC AGCGCCACCATGGTGCTGGAGTCGGTGGTCGCGGACTTGCTGAACCGCTTCCTGGGGGACTATGTGGAGAACCTGAACAAGTCCCAGCTG AAGCTGGGCATCTGGGGCGGAAATGTGGCTTTAGATAATCTACAGATAAAAGAAAATGCCCTGAGTGAATTGGATGTTCCTTTTAAAGTC AAGGCTGGCCAAATTGATAAATTAACTTTGAAGATTCCTTGGAAGAACCTTTATGGAGAAGCAGTTGTTGCGACCCTGGAAGGATTATAC CTGCTTGTTGTCCCTGGAGCAAGTATTAAGTATGATGCTGTAAAAGAAGAAAAATCCTTGCAGGATGTTAAACAGAAAGAGCTATCCCGA ATTGAAGAAGCCCTTCAAAAAGCAGCAGAAAAAGATAAGCCAAAAGAAGCCAAAAAGGATACATTTGTGGAAAAATTGGCAACTCAAGTA ATAAAAAATGTACAAGTAAAAATCACAGATATTCACATTAAATATGAAGATGATGTCACTGATCCAAAGCGGCCTCTTTCATTTGGTGTC ACACTGGGAGAGCTTAGTCTACTGACTGCAAATGAACACTGGACTCCATGCATATTAAATGAAGCAGACAAAATTATATACAAGCTTATA CGACTTGATAGTCTTAGCGCCTACTGGAATGTAAATTGCAGCATGTCTTACCAGAGATCAAGGGAACAGATTTTGGATCAGCTGAAAAAT GAAATTCTTACAAGTGGAAATATACCCCCAAATTATCAATACATTTTCCAGCCAATATCAGCCTCTGCAAAACTCTACATGAATCCTTAT GCAGAATCAGAGCTCAAAACGCCCAAACTGGATTGCAACATAGAAATACAAAATATTGCCATTGAACTGACCAAACCTCAGTACTTAAGT ATGATTGACCTTTTGGAGTCAGTGGATTATATGGTTAGGAATGCGCCTTATAGGAAATACAAGCCTTATTTACCACTTCATACCAATGGT CGACGATGGTGGAAATATGCAATTGATTCTGTTCTTGAAGTTCATATAAGAAGGTATACACAGATGTGGTCATGGAGTAACATAAAAAAG CACAGGCAGTTACTCAAGAGTTATAAAATTGCCTACAAAAACAAGTTAACACAGTCTAAAGTCTCAGAAGAAATACAGAAAGAAATTCAG GACTTGGAGAAGACTCTAGATGTTTTTAACATAATTTTAGCAAGGCAACAAGCACAAGTTGAGGTGATTCGGTCTGGGCAAAAATTAAGG AAAAAGTCTGCTGACACAGGCGAGAAACGTGGAGGCTGGTTTAGTGGGTTGTGGGGTAAGAAAGAGTCTAAGAAAAAGGACGAAGAATCA TTGATTCCTGAAACTATTGATGACCTTATGACTCCAGAGGAAAAAGATAAACTCTTCACTGCCATTGGTTATAGTGAGAGTACCCACAAC CTAACTTTACCTAAGCAGTATGTTGCCCATATTATGACCCTGAAGTTAGTAAGCACCTCTGTTACGATAAGAGAAAACAAGAATATTCCA GAAATACTAAAAATTCAGATAATTGGCCTGGGCACTCAAGTATCTCAGCGACCAGGAGCACAAGCACTTAAGGTAGAAGCGAAATTAGAA CACTGGTATATAACAGGTTTGAGACAGCAGGATATTGTGCCATCACTTGTGGCTTCAATTGGTGACACTACATCATCCTTGCTTAAAATT AAATTTGAAACCAATCCGGAGGATAGTCCTGCTGACCAGACTCTGATTGTTCAGTCCCAGCCTGTGGAGGTCATCTATGATGCTAAAACT GTCAATGCAGTGGTTGAATTCTTTCAATCAAATAAGGGATTGGATCTTGAGCAAATAACATCAGCAACATTGATGAAGCTGGAAGAAATT AAGGAGAGAACAGCTACAGGACTTACACATATTATTGAAACTCGAAAAGTCCTTGATTTAAGGATAAATCTGAAGCCTTCTTATCTAGTA GTTCCACAGACGGGTTTCCACCATGAAAAGTCAGATCTTCTGATTTTAGATTTTGGTACATTTCAGCTCAACAGTAAAGATCAAGGTTTA CAGAAGACTACTAATTCATCTCTGGAAGAAATAATGGATAAGGCATATGACAAGTTTGATGTTGAAATAAAAAATGTACAACTACTTTTT GCAAGAGCAGAGGAAACCTGGAAAAAGTGTCGATTTCAGCATCCATCAACTATGCATATATTGCAACCCATGGATATTCATGTTGAGTTG GCTAAGGCCATGGTAGAAAAAGACATTAGAATGGCCAGATTTAAAGTGTCAGGAGGACTTCCTTTGATGCATGTGAGAATTTCTGACCAG AAGATGAAAGATGTGCTATATTTGATGAACAGTATACCTTTGCCACAGAAATCATCAGCCCAGTCTCCAGAGAGACAGGTATCCTCAATT CCTATTATTTCAGGTGGTACAAAAGGTCTACTTGGTACTTCACTATTGCTAGACACTGTGGAATCAGAGTCTGATGATGAGTATTTTGAT GCTGAAGATGGAGAACCACAGACTTGTAAAAGTATGAAAGGATCAGAACTTAAAAAAGCTGCAGAGGTCCCAAATGAGGAGCTCATCAAT CTTCTACTCAAGTTTGAAATTAAAGAAGTGATTTTGGAATTTACTAAACAGCAGAAAGAAGAAGATACAATTCTAGTATTTAATGTTACT CAGTTAGGAACAGAGGCCACAATGAGAACATTTGACTTAACTGTGGTATCTTATTTAAAGAAAATCAGCTTGGATTATCATGAAATTGAA GGATCCAAAAGGAAGCCCCTTCACTTGATTAGCTCTTCTGACAAACCTGGATTAGATCTTTTGAAAGTGGAGTATATTAAGGCTGATAAG AATGGACCTAGTTTTCAAACTGCTTTTGGAAAAACTGAACAAACAGTTAAGGTGGCCTTTTCATCTTTAAATCTGTTGCTGCAAACACAA GCTCTTGTCGCTTCTATTAATTACCTCACAACCATTATTCCATCTGATGATCAAAGCATAAGTGTTGCTAAGGAGGTACAAATTTCAACT GAAAAACAACAAAAAAATTCAACTCTGCCAAAAGCGATTGTATCCTCCAGAGATAGTGACATTATTGATTTCAGGCTATTTGCCAAGTTG AATGCTTTCTGTGTCATTGTTTGCAACGAAAAGAACAATATCGCCGAAATCAAGATTCAAGGACTGGATTCCTCCCTTTCTCTCCAGTCA AGAAAGCAGTCACTTTTTGCCCGACTAGAAAATATTATTGTCACAGATGTTGATCCAAAGACAGTTCATAAGAAAGCTGTGTCAATAATG GGAAATGAAGTTTTCCGTTTTAATTTGGATTTGTATCCAGATGCTACTGAGGGGGATTTGTATACTGACATGTCCAAAGTGGATGGTGTG CTGTCTCTGAATGTTGGCTGTATTCAGATTGTCTATCTTCATAAATTCCTTATGTCACTTCTGAACTTCCTGAATAATTTCCAGACAGCC AAAGAGTCTCTGAGTGCTGCCACTGCCCAGGCTGCAGAAAGGGCTGCCACAAGTGTGAAAGATCTTGCCCAGAGGAGTTTTCGTGTTTCC ATCAATATTGATTTGAAAGCACCGGTTATAGTCATCCCACAGTCTTCTATTTCCACCAATGCAGTAGTGGTAGATCTTGGGTTAATCAGA GTTCATAATCAGTTCAGTCTGGTGTCTGATGAAGACTACTTAAATCCTCCAGTAATTGATAGAATGGATGTGCAGCTAACAAAGCTTACA CTTTATAGGACAGTGATCCAGCCAGGCATCTACCATCCTGATATTCAGCTGTTGCACCCAATTAACTTGGAATTTCTTGTAAATCGGAAT CTAGCTGCATCTTGGTACCACAAGGTGCCTGTTGTGGAAATTAAAGGACATCTTGATTCAATGAATGTTAGTCTAAATCAAGAAGATCTT AATCTTTTATTTAGGATACTAACAGAAAATCTCTGTGAGGGTACTGAAGACTTGGATAAAGTGAAACCAAGAGTACAAGAGACAGGTGAA ATTAAAGAGCCCCTTGAAATCTCTATATCACAAGATGTACATGATTCAAAAAATACTTTAACAACTGGAGTGGAAGAAATTAGGTCTGTA GACATCATTAATATGCTGCTGAATTTTGAAATTAAAGAGGTTGTGGTTACTTTGATGAAAAAATCAGAAAAGAAAGGAAGGCCTTTACAT GAGCTAAATGTCCTGCAACTTGGAATGGAAGCTAAAGTTAAAACCTATGACATGACTGCTAAAGCTTATCTAAAAAAAATTAGTATGCAG TGCTTTGATTTCACTGACTCTAAAGGGGAACCTCTTCACATTATTAACTCTTCTAATGTGACTGACGAACCCCTTCTGAAAATGTTACTG ACAAAGGCAGACAGTGATGGACCAGAATTTAAAACTATTCATGACAGTACCAAACAGAGACTGAAGGTTTCATTTGCATCCTTAGACTTA GTACTTCATTTGGAAGCTTTACTTTCCTTCATGGATTTTTTATCATCTGCTGCTCCATTCTCTGAGCCTTCCTCTTCTGAGAAGGAATCC GAGCTGAAACCACTTGTGGGGGAGTCCAGAAGTATCGCTGTCAAAGCTGTATCCAGCAACATTTCCCAAAAGGATGTGTTTGATTTAAAG ATCACAGCTGAATTAAATGCATTTAATGTCTTTGTCTGTGATCAGAAGTGTAACATTGCAGATATTAAAATACATGGAATGGATGCCTCT ATTTCTGTGAAGCCTAAGCAGACTGATGTGTTTGCCAGACTTAAAGATATTATAGTTATGAATGTAGATTTGCAGTCCATTCACAAAAAG GCTGTCTCTATTTTGGGAGATGAAGTCTTTAGGTTCCAACTGACTCTTTATCCAGATGCCACAGAAGGAGAGGCCTATGCTGATATGTCC AAAGTAGACGGCAAACTTAGTTTTAAAGTGGGTTGTATTCAGATTGTTTATGTTCATAAATTCTTCATGTCTCTTTTGAACTTCCTCAAC AATTTCCAAACTGCTAAAGAAGCTTTGAGTACAGCCACAGTCCAGGCTGCAGAAAGAGCTGCTTCCAGCATGAAAGACTTGGCTCAAAAG AGTTTCCGCCTTTTGATGGATATTAATTTGAAAGCACCAGTTATTATTATTCCTCAGTCTTCAGTATCACCTAATGCTGTTATAGCAGAT CTGGGTTTAATCAGAGTTGAAAACAAGTTTAGCTTGGTTCCTATGGAACATTATTCTCTTCCTCCAGTCATTGATAAAATGAACATCGAA CTCACTCAGTTGAAGCTGTCAAGAACTATTTTGCAGGCTAGCTTGCCACAAAATGACATTGAAATTTTAAAACCAGTCAACATGCTTTTG TCCATACAGCGAAACTTAGCAGCAGCATGGTATGTGCAAATTCCAGGGATGGAGATAAAAGGAAAACTAAAACCTATGCAGGTGGCTGCA GTCCGAGAAGGGATGTCCTGGATTGTTCCTGTGCCGCTGCTGTCCCTCCTCACAGCAAAACAACTGGAGCAGATGGTGTGTGGGATGCCC GAGATCTCTGTGGAAGTCTTGAAGAAAGTGGTGCGGTACCGTGAGGTGGATGAGCAGCATCAGCTGGTGCAGTGGTTCTGGCACACGCTG GAAGAGTTCTCCAATGAGGAGCGGGTGCTTTTCATGAGGTTTGTGTCAGGAAGATCTCGACTACCAGCCAACACTGCTGACATTTCTCAG AGATTTCAAATCATGAAGGTTGATAGGCCTTACGACAGTCTGCCTACCTCACAGACCTGCTTCTTCCAGCTGAGGCTGCCCCCGTACTCC AGCCAGCTGGTCATGGCCGAGCGCCTGCGCTATGCCATCAACAACTGCCGCTCAATCGACATGGACAACTACATGCTCTCGAGAAACGTG GACAACGCCGAGGGCTCCGACACTGACTACTGACCGTGCGGGTGCTCTCACCCTCCCTTCTCTCCCTCAATAATGCTCACTTCTGATTTG ATGTTGATATACTTTTATGGTAACTACATAGATGTTATAAGAACATAAACCAACATTATAAACAATGGCCACATTTAGTTACTCTAAATG TAACAAAGAAATTAGATGTTTTTATTTTTCTGTGATTGTACAAAAACAACAAAAACGAAGTGCTCTCAGTCAGGTTTTTCCCTCCATATT TTTGGTCACTTTTGATAAGTTTGCATGAAACCATTTTGGTGCATTTTTAGTTGGGAATGGTACATTTTTGTAAATCCACCCAGTGAACAT GAAATTGTACATTGTGTATAATTGTTCATTAGAAAGGACAGTTTTACATGAATATTCATATATTTATTTTGTTTTAATTTGAATTGCCTG >In-frame_VPS13C_ENST00000261517_chr15_62232846_-_HERC1_ENST00000443617_chr15_63904755_-_6630nt TGCAGCGCTGGTCGCAGCCCTCAGCTGCGCCGGGCGGTTCCGGCTCCTCCCTCTCCTTGTGCCTCAGCGCCACCATGGTGCTGGAGTCGG TGGTCGCGGACTTGCTGAACCGCTTCCTGGGGGACTATGTGGAGAACCTGAACAAGTCCCAGCTGAAGCTGGGCATCTGGGGCGGAAATG TGGCTTTAGATAATCTACAGATAAAAGAAAATGCCCTGAGTGAATTGGATGTTCCTTTTAAAGTCAAGGCTGGCCAAATTGATAAATTAA CTTTGAAGATTCCTTGGAAGAACCTTTATGGAGAAGCAGTTGTTGCGACCCTGGAAGGATTATACCTGCTTGTTGTCCCTGGAGCAAGTA TTAAGTATGATGCTGTAAAAGAAGAAAAATCCTTGCAGGATGTTAAACAGAAAGAGCTATCCCGAATTGAAGAAGCCCTTCAAAAAGCAG CAGAAAAAGGCACACATTCAGGGGAGTTCATATATGGCTTGGAGAACTTTGTTTACAAGGACATCAAGCCTGGACGTAAACGTAAAAAGC ACAAAAAACATTTTAAGAAACCTTTTAAAGGTCTTGATCGTTCAAAAGATAAGCCAAAAGAAGCCAAAAAGGATACATTTGTGGAAAAAT TGGCAACTCAAGTAATAAAAAATGTACAAGTAAAAATCACAGATATTCACATTAAATATGAAGATGATGTCACTGATCCAAAGCGGCCTC TTTCATTTGGTGTCACACTGGGAGAGCTTAGTCTACTGACTGCAAATGAACACTGGACTCCATGCATATTAAATGAAGCAGACAAAATTA TATACAAGCTTATACGACTTGATAGTCTTAGCGCCTACTGGAATGTAAATTGCAGCATGTCTTACCAGAGATCAAGGGAACAGATTTTGG ATCAGCTGAAAAATGAAATTCTTACAAGTGGAAATATACCCCCAAATTATCAATACATTTTCCAGCCAATATCAGCCTCTGCAAAACTCT ACATGAATCCTTATGCAGAATCAGAGCTCAAAACGCCCAAACTGGATTGCAACATAGAAATACAAAATATTGCCATTGAACTGACCAAAC CTCAGTACTTAAGTATGATTGACCTTTTGGAGTCAGTGGATTATATGGTTAGGAATGCGCCTTATAGGAAATACAAGCCTTATTTACCAC TTCATACCAATGGTCGACGATGGTGGAAATATGCAATTGATTCTGTTCTTGAAGTTCATATAAGAAGGTATACACAGATGTGGTCATGGA GTAACATAAAAAAGCACAGGCAGTTACTCAAGAGTTATAAAATTGCCTACAAAAACAAGTTAACACAGTCTAAAGTCTCAGAAGAAATAC AGAAAGAAATTCAGGACTTGGAGAAGACTCTAGATGTTTTTAACATAATTTTAGCAAGGCAACAAGCACAAGTTGAGGTGATTCGGTCTG GGCAAAAATTAAGGAAAAAGTCTGCTGACACAGGCGAGAAACGTGGAGGCTGGTTTAGTGGGTTGTGGGGTAAGAAAGAGTCTAAGAAAA AGGACGAAGAATCATTGATTCCTGAAACTATTGATGACCTTATGACTCCAGAGGAAAAAGATAAACTCTTCACTGCCATTGGTTATAGTG AGAGTACCCACAACCTAACTTTACCTAAGCAGTATGTTGCCCATATTATGACCCTGAAGTTAGTAAGCACCTCTGTTACGATAAGAGAAA ACAAGAATATTCCAGAAATACTAAAAATTCAGATAATTGGCCTGGGCACTCAAGTATCTCAGCGACCAGGAGCACAAGCACTTAAGGTAG AAGCGAAATTAGAACACTGGTATATAACAGGTTTGAGACAGCAGGATATTGTGCCATCACTTGTGGCTTCAATTGGTGACACTACATCAT CCTTGCTTAAAATTAAATTTGAAACCAATCCGGAGGATAGTCCTGCTGACCAGACTCTGATTGTTCAGTCCCAGCCTGTGGAGGTCATCT ATGATGCTAAAACTGTCAATGCAGTGGTTGAATTCTTTCAATCAAATAAGGGATTGGATCTTGAGCAAATAACATCAGCAACATTGATGA AGCTGGAAGAAATTAAGGAGAGAACAGCTACAGGACTTACACATATTATTGAAACTCGAAAAGTCCTTGATTTAAGGATAAATCTGAAGC CTTCTTATCTAGTAGTTCCACAGACGGGTTTCCACCATGAAAAGTCAGATCTTCTGATTTTAGATTTTGGTACATTTCAGCTCAACAGTA AAGATCAAGGTTTACAGAAGACTACTAATTCATCTCTGGAAGAAATAATGGATAAGGCATATGACAAGTTTGATGTTGAAATAAAAAATG TACAACTACTTTTTGCAAGAGCAGAGGAAACCTGGAAAAAGTGTCGATTTCAGCATCCATCAACTATGCATATATTGCAACCCATGGATA TTCATGTTGAGTTGGCTAAGGCCATGGTAGAAAAAGACATTAGAATGGCCAGATTTAAAGTGTCAGGAGGACTTCCTTTGATGCATGTGA GAATTTCTGACCAGAAGATGAAAGATGTGCTATATTTGATGAACAGTATACCTTTGCCACAGAAATCATCAGCCCAGTCTCCAGAGAGAC AGGTATCCTCAATTCCTATTATTTCAGGTGGTACAAAAGGTCTACTTGGTACTTCACTATTGCTAGACACTGTGGAATCAGAGTCTGATG ATGAGTATTTTGATGCTGAAGATGGAGAACCACAGACTTGTAAAAGTATGAAAGGATCAGAACTTAAAAAAGCTGCAGAGGTCCCAAATG AGGAGCTCATCAATCTTCTACTCAAGTTTGAAATTAAAGAAGTGATTTTGGAATTTACTAAACAGCAGAAAGAAGAAGATACAATTCTAG TATTTAATGTTACTCAGTTAGGAACAGAGGCCACAATGAGAACATTTGACTTAACTGTGGTATCTTATTTAAAGAAAATCAGCTTGGATT ATCATGAAATTGAAGGATCCAAAAGGAAGCCCCTTCACTTGATTAGCTCTTCTGACAAACCTGGATTAGATCTTTTGAAAGTGGAGTATA TTAAGGCTGATAAGAATGGACCTAGTTTTCAAACTGCTTTTGGAAAAACTGAACAAACAGTTAAGGTGGCCTTTTCATCTTTAAATCTGT TGCTGCAAACACAAGCTCTTGTCGCTTCTATTAATTACCTCACAACCATTATTCCATCTGATGATCAAAGCATAAGTGTTGCTAAGGAGG TACAAATTTCAACTGAAAAACAACAAAAAAATTCAACTCTGCCAAAAGCGATTGTATCCTCCAGAGATAGTGACATTATTGATTTCAGGC TATTTGCCAAGTTGAATGCTTTCTGTGTCATTGTTTGCAACGAAAAGAACAATATCGCCGAAATCAAGATTCAAGGACTGGATTCCTCCC TTTCTCTCCAGTCAAGAAAGCAGTCACTTTTTGCCCGACTAGAAAATATTATTGTCACAGATGTTGATCCAAAGACAGTTCATAAGAAAG CTGTGTCAATAATGGGAAATGAAGTTTTCCGTTTTAATTTGGATTTGTATCCAGATGCTACTGAGGGGGATTTGTATACTGACATGTCCA AAGTGGATGGTGTGCTGTCTCTGAATGTTGGCTGTATTCAGATTGTCTATCTTCATAAATTCCTTATGTCACTTCTGAACTTCCTGAATA ATTTCCAGACAGCCAAAGAGTCTCTGAGTGCTGCCACTGCCCAGGCTGCAGAAAGGGCTGCCACAAGTGTGAAAGATCTTGCCCAGAGGA GTTTTCGTGTTTCCATCAATATTGATTTGAAAGCACCGGTTATAGTCATCCCACAGTCTTCTATTTCCACCAATGCAGTAGTGGTAGATC TTGGGTTAATCAGAGTTCATAATCAGTTCAGTCTGGTGTCTGATGAAGACTACTTAAATCCTCCAGTAATTGATAGAATGGATGTGCAGC TAACAAAGCTTACACTTTATAGGACAGTGATCCAGCCAGGCATCTACCATCCTGATATTCAGCTGTTGCACCCAATTAACTTGGAATTTC TTGTAAATCGGAATCTAGCTGCATCTTGGTACCACAAGGTGCCTGTTGTGGAAATTAAAGGACATCTTGATTCAATGAATGTTAGTCTAA ATCAAGAAGATCTTAATCTTTTATTTAGGATACTAACAGAAAATCTCTGTGAGGGTACTGAAGACTTGGATAAAGTGAAACCAAGAGTAC AAGAGACAGGTGAAATTAAAGAGCCCCTTGAAATCTCTATATCACAAGATGTACATGATTCAAAAAATACTTTAACAACTGGAGTGGAAG AAATTAGGTCTGTAGACATCATTAATATGCTGCTGAATTTTGAAATTAAAGAGGTTGTGGTTACTTTGATGAAAAAATCAGAAAAGAAAG GAAGGCCTTTACATGAGCTAAATGTCCTGCAACTTGGAATGGAAGCTAAAGTTAAAACCTATGACATGACTGCTAAAGCTTATCTAAAAA AAATTAGTATGCAGTGCTTTGATTTCACTGACTCTAAAGGGGAACCTCTTCACATTATTAACTCTTCTAATGTGACTGACGAACCCCTTC TGAAAATGTTACTGACAAAGGCAGACAGTGATGGACCAGAATTTAAAACTATTCATGACAGTACCAAACAGAGACTGAAGGTTTCATTTG CATCCTTAGACTTAGTACTTCATTTGGAAGCTTTACTTTCCTTCATGGATTTTTTATCATCTGCTGCTCCATTCTCTGAGCCTTCCTCTT CTGAGAAGGAATCCGAGCTGAAACCACTTGTGGGGGAGTCCAGAAGTATCGCTGTCAAAGCTGTATCCAGCAACATTTCCCAAAAGGATG TGTTTGATTTAAAGATCACAGCTGAATTAAATGCATTTAATGTCTTTGTCTGTGATCAGAAGTGTAACATTGCAGATATTAAAATACATG GAATGGATGCCTCTATTTCTGTGAAGCCTAAGCAGACTGATGTGTTTGCCAGACTTAAAGATATTATAGTTATGAATGTAGATTTGCAGT CCATTCACAAAAAGGCTGTCTCTATTTTGGGAGATGAAGTCTTTAGGTTCCAACTGACTCTTTATCCAGATGCCACAGAAGGAGAGGCCT ATGCTGATATGTCCAAAGTAGACGGCAAACTTAGTTTTAAAGTGGGTTGTATTCAGATTGTTTATGTTCATAAATTCTTCATGTCTCTTT TGAACTTCCTCAACAATTTCCAAACTGCTAAAGAAGCTTTGAGTACAGCCACAGTCCAGGCTGCAGAAAGAGCTGCTTCCAGCATGAAAG ACTTGGCTCAAAAGAGTTTCCGCCTTTTGATGGATATTAATTTGAAAGCACCAGTTATTATTATTCCTCAGTCTTCAGTATCACCTAATG CTGTTATAGCAGATCTGGGTTTAATCAGAGTTGAAAACAAGTTTAGCTTGGTTCCTATGGAACATTATTCTCTTCCTCCAGTCATTGATA AAATGAACATCGAACTCACTCAGTTGAAGCTGTCAAGAACTATTTTGCAGGCTAGCTTGCCACAAAATGACATTGAAATTTTAAAACCAG TCAACATGCTTTTGTCCATACAGCGAAACTTAGCAGCAGCATGGTATGTGCAAATTCCAGGGATGGAGATAAAAGGAAAACTAAAACCTA TGCAGGTGGCTGCAGTCCGAGAAGGGATGTCCTGGATTGTTCCTGTGCCGCTGCTGTCCCTCCTCACAGCAAAACAACTGGAGCAGATGG TGTGTGGGATGCCCGAGATCTCTGTGGAAGTCTTGAAGAAAGTGGTGCGGTACCGTGAGGTGGATGAGCAGCATCAGCTGGTGCAGTGGT TCTGGCACACGCTGGAAGAGTTCTCCAATGAGGAGCGGGTGCTTTTCATGAGGTTTGTGTCAGGAAGATCTCGACTACCAGCCAACACTG CTGACATTTCTCAGAGATTTCAAATCATGAAGGTTGATAGGCCTTACGACAGTCTGCCTACCTCACAGACCTGCTTCTTCCAGCTGAGGC TGCCCCCGTACTCCAGCCAGCTGGTCATGGCCGAGCGCCTGCGCTATGCCATCAACAACTGCCGCTCAATCGACATGGACAACTACATGC TCTCGAGAAACGTGGACAACGCCGAGGGCTCCGACACTGACTACTGACCGTGCGGGTGCTCTCACCCTCCCTTCTCTCCCTCAATAATGC TCACTTCTGATTTGATGTTGATATACTTTTATGGTAACTACATAGATGTTATAAGAACATAAACCAACATTATAAACAATGGCCACATTT AGTTACTCTAAATGTAACAAAGAAATTAGATGTTTTTATTTTTCTGTGATTGTACAAAAACAACAAAAACGAAGTGCTCTCAGTCAGGTT TTTCCCTCCATATTTTTGGTCACTTTTGATAAGTTTGCATGAAACCATTTTGGTGCATTTTTAGTTGGGAATGGTACATTTTTGTAAATC CACCCAGTGAACATGAAATTGTACATTGTGTATAATTGTTCATTAGAAAGGACAGTTTTACATGAATATTCATATATTTATTTTGTTTTA >In-frame_VPS13C_ENST00000395896_chr15_62232846_-_HERC1_ENST00000443617_chr15_63904755_-_6630nt TGCAGCGCTGGTCGCAGCCCTCAGCTGCGCCGGGCGGTTCCGGCTCCTCCCTCTCCTTGTGCCTCAGCGCCACCATGGTGCTGGAGTCGG TGGTCGCGGACTTGCTGAACCGCTTCCTGGGGGACTATGTGGAGAACCTGAACAAGTCCCAGCTGAAGCTGGGCATCTGGGGCGGAAATG TGGCTTTAGATAATCTACAGATAAAAGAAAATGCCCTGAGTGAATTGGATGTTCCTTTTAAAGTCAAGGCTGGCCAAATTGATAAATTAA CTTTGAAGATTCCTTGGAAGAACCTTTATGGAGAAGCAGTTGTTGCGACCCTGGAAGGATTATACCTGCTTGTTGTCCCTGGAGCAAGTA TTAAGTATGATGCTGTAAAAGAAGAAAAATCCTTGCAGGATGTTAAACAGAAAGAGCTATCCCGAATTGAAGAAGCCCTTCAAAAAGCAG CAGAAAAAGGCACACATTCAGGGGAGTTCATATATGGCTTGGAGAACTTTGTTTACAAGGACATCAAGCCTGGACGTAAACGTAAAAAGC ACAAAAAACATTTTAAGAAACCTTTTAAAGGTCTTGATCGTTCAAAAGATAAGCCAAAAGAAGCCAAAAAGGATACATTTGTGGAAAAAT TGGCAACTCAAGTAATAAAAAATGTACAAGTAAAAATCACAGATATTCACATTAAATATGAAGATGATGTCACTGATCCAAAGCGGCCTC TTTCATTTGGTGTCACACTGGGAGAGCTTAGTCTACTGACTGCAAATGAACACTGGACTCCATGCATATTAAATGAAGCAGACAAAATTA TATACAAGCTTATACGACTTGATAGTCTTAGCGCCTACTGGAATGTAAATTGCAGCATGTCTTACCAGAGATCAAGGGAACAGATTTTGG ATCAGCTGAAAAATGAAATTCTTACAAGTGGAAATATACCCCCAAATTATCAATACATTTTCCAGCCAATATCAGCCTCTGCAAAACTCT ACATGAATCCTTATGCAGAATCAGAGCTCAAAACGCCCAAACTGGATTGCAACATAGAAATACAAAATATTGCCATTGAACTGACCAAAC CTCAGTACTTAAGTATGATTGACCTTTTGGAGTCAGTGGATTATATGGTTAGGAATGCGCCTTATAGGAAATACAAGCCTTATTTACCAC TTCATACCAATGGTCGACGATGGTGGAAATATGCAATTGATTCTGTTCTTGAAGTTCATATAAGAAGGTATACACAGATGTGGTCATGGA GTAACATAAAAAAGCACAGGCAGTTACTCAAGAGTTATAAAATTGCCTACAAAAACAAGTTAACACAGTCTAAAGTCTCAGAAGAAATAC AGAAAGAAATTCAGGACTTGGAGAAGACTCTAGATGTTTTTAACATAATTTTAGCAAGGCAACAAGCACAAGTTGAGGTGATTCGGTCTG GGCAAAAATTAAGGAAAAAGTCTGCTGACACAGGCGAGAAACGTGGAGGCTGGTTTAGTGGGTTGTGGGGTAAGAAAGAGTCTAAGAAAA AGGACGAAGAATCATTGATTCCTGAAACTATTGATGACCTTATGACTCCAGAGGAAAAAGATAAACTCTTCACTGCCATTGGTTATAGTG AGAGTACCCACAACCTAACTTTACCTAAGCAGTATGTTGCCCATATTATGACCCTGAAGTTAGTAAGCACCTCTGTTACGATAAGAGAAA ACAAGAATATTCCAGAAATACTAAAAATTCAGATAATTGGCCTGGGCACTCAAGTATCTCAGCGACCAGGAGCACAAGCACTTAAGGTAG AAGCGAAATTAGAACACTGGTATATAACAGGTTTGAGACAGCAGGATATTGTGCCATCACTTGTGGCTTCAATTGGTGACACTACATCAT CCTTGCTTAAAATTAAATTTGAAACCAATCCGGAGGATAGTCCTGCTGACCAGACTCTGATTGTTCAGTCCCAGCCTGTGGAGGTCATCT ATGATGCTAAAACTGTCAATGCAGTGGTTGAATTCTTTCAATCAAATAAGGGATTGGATCTTGAGCAAATAACATCAGCAACATTGATGA AGCTGGAAGAAATTAAGGAGAGAACAGCTACAGGACTTACACATATTATTGAAACTCGAAAAGTCCTTGATTTAAGGATAAATCTGAAGC CTTCTTATCTAGTAGTTCCACAGACGGGTTTCCACCATGAAAAGTCAGATCTTCTGATTTTAGATTTTGGTACATTTCAGCTCAACAGTA AAGATCAAGGTTTACAGAAGACTACTAATTCATCTCTGGAAGAAATAATGGATAAGGCATATGACAAGTTTGATGTTGAAATAAAAAATG TACAACTACTTTTTGCAAGAGCAGAGGAAACCTGGAAAAAGTGTCGATTTCAGCATCCATCAACTATGCATATATTGCAACCCATGGATA TTCATGTTGAGTTGGCTAAGGCCATGGTAGAAAAAGACATTAGAATGGCCAGATTTAAAGTGTCAGGAGGACTTCCTTTGATGCATGTGA GAATTTCTGACCAGAAGATGAAAGATGTGCTATATTTGATGAACAGTATACCTTTGCCACAGAAATCATCAGCCCAGTCTCCAGAGAGAC AGGTATCCTCAATTCCTATTATTTCAGGTGGTACAAAAGGTCTACTTGGTACTTCACTATTGCTAGACACTGTGGAATCAGAGTCTGATG ATGAGTATTTTGATGCTGAAGATGGAGAACCACAGACTTGTAAAAGTATGAAAGGATCAGAACTTAAAAAAGCTGCAGAGGTCCCAAATG AGGAGCTCATCAATCTTCTACTCAAGTTTGAAATTAAAGAAGTGATTTTGGAATTTACTAAACAGCAGAAAGAAGAAGATACAATTCTAG TATTTAATGTTACTCAGTTAGGAACAGAGGCCACAATGAGAACATTTGACTTAACTGTGGTATCTTATTTAAAGAAAATCAGCTTGGATT ATCATGAAATTGAAGGATCCAAAAGGAAGCCCCTTCACTTGATTAGCTCTTCTGACAAACCTGGATTAGATCTTTTGAAAGTGGAGTATA TTAAGGCTGATAAGAATGGACCTAGTTTTCAAACTGCTTTTGGAAAAACTGAACAAACAGTTAAGGTGGCCTTTTCATCTTTAAATCTGT TGCTGCAAACACAAGCTCTTGTCGCTTCTATTAATTACCTCACAACCATTATTCCATCTGATGATCAAAGCATAAGTGTTGCTAAGGAGG TACAAATTTCAACTGAAAAACAACAAAAAAATTCAACTCTGCCAAAAGCGATTGTATCCTCCAGAGATAGTGACATTATTGATTTCAGGC TATTTGCCAAGTTGAATGCTTTCTGTGTCATTGTTTGCAACGAAAAGAACAATATCGCCGAAATCAAGATTCAAGGACTGGATTCCTCCC TTTCTCTCCAGTCAAGAAAGCAGTCACTTTTTGCCCGACTAGAAAATATTATTGTCACAGATGTTGATCCAAAGACAGTTCATAAGAAAG CTGTGTCAATAATGGGAAATGAAGTTTTCCGTTTTAATTTGGATTTGTATCCAGATGCTACTGAGGGGGATTTGTATACTGACATGTCCA AAGTGGATGGTGTGCTGTCTCTGAATGTTGGCTGTATTCAGATTGTCTATCTTCATAAATTCCTTATGTCACTTCTGAACTTCCTGAATA ATTTCCAGACAGCCAAAGAGTCTCTGAGTGCTGCCACTGCCCAGGCTGCAGAAAGGGCTGCCACAAGTGTGAAAGATCTTGCCCAGAGGA GTTTTCGTGTTTCCATCAATATTGATTTGAAAGCACCGGTTATAGTCATCCCACAGTCTTCTATTTCCACCAATGCAGTAGTGGTAGATC TTGGGTTAATCAGAGTTCATAATCAGTTCAGTCTGGTGTCTGATGAAGACTACTTAAATCCTCCAGTAATTGATAGAATGGATGTGCAGC TAACAAAGCTTACACTTTATAGGACAGTGATCCAGCCAGGCATCTACCATCCTGATATTCAGCTGTTGCACCCAATTAACTTGGAATTTC TTGTAAATCGGAATCTAGCTGCATCTTGGTACCACAAGGTGCCTGTTGTGGAAATTAAAGGACATCTTGATTCAATGAATGTTAGTCTAA ATCAAGAAGATCTTAATCTTTTATTTAGGATACTAACAGAAAATCTCTGTGAGGGTACTGAAGACTTGGATAAAGTGAAACCAAGAGTAC AAGAGACAGGTGAAATTAAAGAGCCCCTTGAAATCTCTATATCACAAGATGTACATGATTCAAAAAATACTTTAACAACTGGAGTGGAAG AAATTAGGTCTGTAGACATCATTAATATGCTGCTGAATTTTGAAATTAAAGAGGTTGTGGTTACTTTGATGAAAAAATCAGAAAAGAAAG GAAGGCCTTTACATGAGCTAAATGTCCTGCAACTTGGAATGGAAGCTAAAGTTAAAACCTATGACATGACTGCTAAAGCTTATCTAAAAA AAATTAGTATGCAGTGCTTTGATTTCACTGACTCTAAAGGGGAACCTCTTCACATTATTAACTCTTCTAATGTGACTGACGAACCCCTTC TGAAAATGTTACTGACAAAGGCAGACAGTGATGGACCAGAATTTAAAACTATTCATGACAGTACCAAACAGAGACTGAAGGTTTCATTTG CATCCTTAGACTTAGTACTTCATTTGGAAGCTTTACTTTCCTTCATGGATTTTTTATCATCTGCTGCTCCATTCTCTGAGCCTTCCTCTT CTGAGAAGGAATCCGAGCTGAAACCACTTGTGGGGGAGTCCAGAAGTATCGCTGTCAAAGCTGTATCCAGCAACATTTCCCAAAAGGATG TGTTTGATTTAAAGATCACAGCTGAATTAAATGCATTTAATGTCTTTGTCTGTGATCAGAAGTGTAACATTGCAGATATTAAAATACATG GAATGGATGCCTCTATTTCTGTGAAGCCTAAGCAGACTGATGTGTTTGCCAGACTTAAAGATATTATAGTTATGAATGTAGATTTGCAGT CCATTCACAAAAAGGCTGTCTCTATTTTGGGAGATGAAGTCTTTAGGTTCCAACTGACTCTTTATCCAGATGCCACAGAAGGAGAGGCCT ATGCTGATATGTCCAAAGTAGACGGCAAACTTAGTTTTAAAGTGGGTTGTATTCAGATTGTTTATGTTCATAAATTCTTCATGTCTCTTT TGAACTTCCTCAACAATTTCCAAACTGCTAAAGAAGCTTTGAGTACAGCCACAGTCCAGGCTGCAGAAAGAGCTGCTTCCAGCATGAAAG ACTTGGCTCAAAAGAGTTTCCGCCTTTTGATGGATATTAATTTGAAAGCACCAGTTATTATTATTCCTCAGTCTTCAGTATCACCTAATG CTGTTATAGCAGATCTGGGTTTAATCAGAGTTGAAAACAAGTTTAGCTTGGTTCCTATGGAACATTATTCTCTTCCTCCAGTCATTGATA AAATGAACATCGAACTCACTCAGTTGAAGCTGTCAAGAACTATTTTGCAGGCTAGCTTGCCACAAAATGACATTGAAATTTTAAAACCAG TCAACATGCTTTTGTCCATACAGCGAAACTTAGCAGCAGCATGGTATGTGCAAATTCCAGGGATGGAGATAAAAGGAAAACTAAAACCTA TGCAGGTGGCTGCAGTCCGAGAAGGGATGTCCTGGATTGTTCCTGTGCCGCTGCTGTCCCTCCTCACAGCAAAACAACTGGAGCAGATGG TGTGTGGGATGCCCGAGATCTCTGTGGAAGTCTTGAAGAAAGTGGTGCGGTACCGTGAGGTGGATGAGCAGCATCAGCTGGTGCAGTGGT TCTGGCACACGCTGGAAGAGTTCTCCAATGAGGAGCGGGTGCTTTTCATGAGGTTTGTGTCAGGAAGATCTCGACTACCAGCCAACACTG CTGACATTTCTCAGAGATTTCAAATCATGAAGGTTGATAGGCCTTACGACAGTCTGCCTACCTCACAGACCTGCTTCTTCCAGCTGAGGC TGCCCCCGTACTCCAGCCAGCTGGTCATGGCCGAGCGCCTGCGCTATGCCATCAACAACTGCCGCTCAATCGACATGGACAACTACATGC TCTCGAGAAACGTGGACAACGCCGAGGGCTCCGACACTGACTACTGACCGTGCGGGTGCTCTCACCCTCCCTTCTCTCCCTCAATAATGC TCACTTCTGATTTGATGTTGATATACTTTTATGGTAACTACATAGATGTTATAAGAACATAAACCAACATTATAAACAATGGCCACATTT AGTTACTCTAAATGTAACAAAGAAATTAGATGTTTTTATTTTTCTGTGATTGTACAAAAACAACAAAAACGAAGTGCTCTCAGTCAGGTT TTTCCCTCCATATTTTTGGTCACTTTTGATAAGTTTGCATGAAACCATTTTGGTGCATTTTTAGTTGGGAATGGTACATTTTTGTAAATC CACCCAGTGAACATGAAATTGTACATTGTGTATAATTGTTCATTAGAAAGGACAGTTTTACATGAATATTCATATATTTATTTTGTTTTA >In-frame_VPS13C_ENST00000395898_chr15_62232846_-_HERC1_ENST00000443617_chr15_63904755_-_6501nt TGCAGCGCTGGTCGCAGCCCTCAGCTGCGCCGGGCGGTTCCGGCTCCTCCCTCTCCTTGTGCCTCAGCGCCACCATGGTGCTGGAGTCGG TGGTCGCGGACTTGCTGAACCGCTTCCTGGGGGACTATGTGGAGAACCTGAACAAGTCCCAGCTGAAGCTGGGCATCTGGGGCGGAAATG TGGCTTTAGATAATCTACAGATAAAAGAAAATGCCCTGAGTGAATTGGATGTTCCTTTTAAAGTCAAGGCTGGCCAAATTGATAAATTAA CTTTGAAGATTCCTTGGAAGAACCTTTATGGAGAAGCAGTTGTTGCGACCCTGGAAGGATTATACCTGCTTGTTGTCCCTGGAGCAAGTA TTAAGTATGATGCTGTAAAAGAAGAAAAATCCTTGCAGGATGTTAAACAGAAAGAGCTATCCCGAATTGAAGAAGCCCTTCAAAAAGCAG CAGAAAAAGATAAGCCAAAAGAAGCCAAAAAGGATACATTTGTGGAAAAATTGGCAACTCAAGTAATAAAAAATGTACAAGTAAAAATCA CAGATATTCACATTAAATATGAAGATGATGTCACTGATCCAAAGCGGCCTCTTTCATTTGGTGTCACACTGGGAGAGCTTAGTCTACTGA CTGCAAATGAACACTGGACTCCATGCATATTAAATGAAGCAGACAAAATTATATACAAGCTTATACGACTTGATAGTCTTAGCGCCTACT GGAATGTAAATTGCAGCATGTCTTACCAGAGATCAAGGGAACAGATTTTGGATCAGCTGAAAAATGAAATTCTTACAAGTGGAAATATAC CCCCAAATTATCAATACATTTTCCAGCCAATATCAGCCTCTGCAAAACTCTACATGAATCCTTATGCAGAATCAGAGCTCAAAACGCCCA AACTGGATTGCAACATAGAAATACAAAATATTGCCATTGAACTGACCAAACCTCAGTACTTAAGTATGATTGACCTTTTGGAGTCAGTGG ATTATATGGTTAGGAATGCGCCTTATAGGAAATACAAGCCTTATTTACCACTTCATACCAATGGTCGACGATGGTGGAAATATGCAATTG ATTCTGTTCTTGAAGTTCATATAAGAAGGTATACACAGATGTGGTCATGGAGTAACATAAAAAAGCACAGGCAGTTACTCAAGAGTTATA AAATTGCCTACAAAAACAAGTTAACACAGTCTAAAGTCTCAGAAGAAATACAGAAAGAAATTCAGGACTTGGAGAAGACTCTAGATGTTT TTAACATAATTTTAGCAAGGCAACAAGCACAAGTTGAGGTGATTCGGTCTGGGCAAAAATTAAGGAAAAAGTCTGCTGACACAGGCGAGA AACGTGGAGGCTGGTTTAGTGGGTTGTGGGGTAAGAAAGAGTCTAAGAAAAAGGACGAAGAATCATTGATTCCTGAAACTATTGATGACC TTATGACTCCAGAGGAAAAAGATAAACTCTTCACTGCCATTGGTTATAGTGAGAGTACCCACAACCTAACTTTACCTAAGCAGTATGTTG CCCATATTATGACCCTGAAGTTAGTAAGCACCTCTGTTACGATAAGAGAAAACAAGAATATTCCAGAAATACTAAAAATTCAGATAATTG GCCTGGGCACTCAAGTATCTCAGCGACCAGGAGCACAAGCACTTAAGGTAGAAGCGAAATTAGAACACTGGTATATAACAGGTTTGAGAC AGCAGGATATTGTGCCATCACTTGTGGCTTCAATTGGTGACACTACATCATCCTTGCTTAAAATTAAATTTGAAACCAATCCGGAGGATA GTCCTGCTGACCAGACTCTGATTGTTCAGTCCCAGCCTGTGGAGGTCATCTATGATGCTAAAACTGTCAATGCAGTGGTTGAATTCTTTC AATCAAATAAGGGATTGGATCTTGAGCAAATAACATCAGCAACATTGATGAAGCTGGAAGAAATTAAGGAGAGAACAGCTACAGGACTTA CACATATTATTGAAACTCGAAAAGTCCTTGATTTAAGGATAAATCTGAAGCCTTCTTATCTAGTAGTTCCACAGACGGGTTTCCACCATG AAAAGTCAGATCTTCTGATTTTAGATTTTGGTACATTTCAGCTCAACAGTAAAGATCAAGGTTTACAGAAGACTACTAATTCATCTCTGG AAGAAATAATGGATAAGGCATATGACAAGTTTGATGTTGAAATAAAAAATGTACAACTACTTTTTGCAAGAGCAGAGGAAACCTGGAAAA AGTGTCGATTTCAGCATCCATCAACTATGCATATATTGCAACCCATGGATATTCATGTTGAGTTGGCTAAGGCCATGGTAGAAAAAGACA TTAGAATGGCCAGATTTAAAGTGTCAGGAGGACTTCCTTTGATGCATGTGAGAATTTCTGACCAGAAGATGAAAGATGTGCTATATTTGA TGAACAGTATACCTTTGCCACAGAAATCATCAGCCCAGTCTCCAGAGAGACAGGTATCCTCAATTCCTATTATTTCAGGTGGTACAAAAG GTCTACTTGGTACTTCACTATTGCTAGACACTGTGGAATCAGAGTCTGATGATGAGTATTTTGATGCTGAAGATGGAGAACCACAGACTT GTAAAAGTATGAAAGGATCAGAACTTAAAAAAGCTGCAGAGGTCCCAAATGAGGAGCTCATCAATCTTCTACTCAAGTTTGAAATTAAAG AAGTGATTTTGGAATTTACTAAACAGCAGAAAGAAGAAGATACAATTCTAGTATTTAATGTTACTCAGTTAGGAACAGAGGCCACAATGA GAACATTTGACTTAACTGTGGTATCTTATTTAAAGAAAATCAGCTTGGATTATCATGAAATTGAAGGATCCAAAAGGAAGCCCCTTCACT TGATTAGCTCTTCTGACAAACCTGGATTAGATCTTTTGAAAGTGGAGTATATTAAGGCTGATAAGAATGGACCTAGTTTTCAAACTGCTT TTGGAAAAACTGAACAAACAGTTAAGGTGGCCTTTTCATCTTTAAATCTGTTGCTGCAAACACAAGCTCTTGTCGCTTCTATTAATTACC TCACAACCATTATTCCATCTGATGATCAAAGCATAAGTGTTGCTAAGGAGGTACAAATTTCAACTGAAAAACAACAAAAAAATTCAACTC TGCCAAAAGCGATTGTATCCTCCAGAGATAGTGACATTATTGATTTCAGGCTATTTGCCAAGTTGAATGCTTTCTGTGTCATTGTTTGCA ACGAAAAGAACAATATCGCCGAAATCAAGATTCAAGGACTGGATTCCTCCCTTTCTCTCCAGTCAAGAAAGCAGTCACTTTTTGCCCGAC TAGAAAATATTATTGTCACAGATGTTGATCCAAAGACAGTTCATAAGAAAGCTGTGTCAATAATGGGAAATGAAGTTTTCCGTTTTAATT TGGATTTGTATCCAGATGCTACTGAGGGGGATTTGTATACTGACATGTCCAAAGTGGATGGTGTGCTGTCTCTGAATGTTGGCTGTATTC AGATTGTCTATCTTCATAAATTCCTTATGTCACTTCTGAACTTCCTGAATAATTTCCAGACAGCCAAAGAGTCTCTGAGTGCTGCCACTG CCCAGGCTGCAGAAAGGGCTGCCACAAGTGTGAAAGATCTTGCCCAGAGGAGTTTTCGTGTTTCCATCAATATTGATTTGAAAGCACCGG TTATAGTCATCCCACAGTCTTCTATTTCCACCAATGCAGTAGTGGTAGATCTTGGGTTAATCAGAGTTCATAATCAGTTCAGTCTGGTGT CTGATGAAGACTACTTAAATCCTCCAGTAATTGATAGAATGGATGTGCAGCTAACAAAGCTTACACTTTATAGGACAGTGATCCAGCCAG GCATCTACCATCCTGATATTCAGCTGTTGCACCCAATTAACTTGGAATTTCTTGTAAATCGGAATCTAGCTGCATCTTGGTACCACAAGG TGCCTGTTGTGGAAATTAAAGGACATCTTGATTCAATGAATGTTAGTCTAAATCAAGAAGATCTTAATCTTTTATTTAGGATACTAACAG AAAATCTCTGTGAGGGTACTGAAGACTTGGATAAAGTGAAACCAAGAGTACAAGAGACAGGTGAAATTAAAGAGCCCCTTGAAATCTCTA TATCACAAGATGTACATGATTCAAAAAATACTTTAACAACTGGAGTGGAAGAAATTAGGTCTGTAGACATCATTAATATGCTGCTGAATT TTGAAATTAAAGAGGTTGTGGTTACTTTGATGAAAAAATCAGAAAAGAAAGGAAGGCCTTTACATGAGCTAAATGTCCTGCAACTTGGAA TGGAAGCTAAAGTTAAAACCTATGACATGACTGCTAAAGCTTATCTAAAAAAAATTAGTATGCAGTGCTTTGATTTCACTGACTCTAAAG GGGAACCTCTTCACATTATTAACTCTTCTAATGTGACTGACGAACCCCTTCTGAAAATGTTACTGACAAAGGCAGACAGTGATGGACCAG AATTTAAAACTATTCATGACAGTACCAAACAGAGACTGAAGGTTTCATTTGCATCCTTAGACTTAGTACTTCATTTGGAAGCTTTACTTT CCTTCATGGATTTTTTATCATCTGCTGCTCCATTCTCTGAGCCTTCCTCTTCTGAGAAGGAATCCGAGCTGAAACCACTTGTGGGGGAGT CCAGAAGTATCGCTGTCAAAGCTGTATCCAGCAACATTTCCCAAAAGGATGTGTTTGATTTAAAGATCACAGCTGAATTAAATGCATTTA ATGTCTTTGTCTGTGATCAGAAGTGTAACATTGCAGATATTAAAATACATGGAATGGATGCCTCTATTTCTGTGAAGCCTAAGCAGACTG ATGTGTTTGCCAGACTTAAAGATATTATAGTTATGAATGTAGATTTGCAGTCCATTCACAAAAAGGCTGTCTCTATTTTGGGAGATGAAG TCTTTAGGTTCCAACTGACTCTTTATCCAGATGCCACAGAAGGAGAGGCCTATGCTGATATGTCCAAAGTAGACGGCAAACTTAGTTTTA AAGTGGGTTGTATTCAGATTGTTTATGTTCATAAATTCTTCATGTCTCTTTTGAACTTCCTCAACAATTTCCAAACTGCTAAAGAAGCTT TGAGTACAGCCACAGTCCAGGCTGCAGAAAGAGCTGCTTCCAGCATGAAAGACTTGGCTCAAAAGAGTTTCCGCCTTTTGATGGATATTA ATTTGAAAGCACCAGTTATTATTATTCCTCAGTCTTCAGTATCACCTAATGCTGTTATAGCAGATCTGGGTTTAATCAGAGTTGAAAACA AGTTTAGCTTGGTTCCTATGGAACATTATTCTCTTCCTCCAGTCATTGATAAAATGAACATCGAACTCACTCAGTTGAAGCTGTCAAGAA CTATTTTGCAGGCTAGCTTGCCACAAAATGACATTGAAATTTTAAAACCAGTCAACATGCTTTTGTCCATACAGCGAAACTTAGCAGCAG CATGGTATGTGCAAATTCCAGGGATGGAGATAAAAGGAAAACTAAAACCTATGCAGGTGGCTGCAGTCCGAGAAGGGATGTCCTGGATTG TTCCTGTGCCGCTGCTGTCCCTCCTCACAGCAAAACAACTGGAGCAGATGGTGTGTGGGATGCCCGAGATCTCTGTGGAAGTCTTGAAGA AAGTGGTGCGGTACCGTGAGGTGGATGAGCAGCATCAGCTGGTGCAGTGGTTCTGGCACACGCTGGAAGAGTTCTCCAATGAGGAGCGGG TGCTTTTCATGAGGTTTGTGTCAGGAAGATCTCGACTACCAGCCAACACTGCTGACATTTCTCAGAGATTTCAAATCATGAAGGTTGATA GGCCTTACGACAGTCTGCCTACCTCACAGACCTGCTTCTTCCAGCTGAGGCTGCCCCCGTACTCCAGCCAGCTGGTCATGGCCGAGCGCC TGCGCTATGCCATCAACAACTGCCGCTCAATCGACATGGACAACTACATGCTCTCGAGAAACGTGGACAACGCCGAGGGCTCCGACACTG ACTACTGACCGTGCGGGTGCTCTCACCCTCCCTTCTCTCCCTCAATAATGCTCACTTCTGATTTGATGTTGATATACTTTTATGGTAACT ACATAGATGTTATAAGAACATAAACCAACATTATAAACAATGGCCACATTTAGTTACTCTAAATGTAACAAAGAAATTAGATGTTTTTAT TTTTCTGTGATTGTACAAAAACAACAAAAACGAAGTGCTCTCAGTCAGGTTTTTCCCTCCATATTTTTGGTCACTTTTGATAAGTTTGCA TGAAACCATTTTGGTGCATTTTTAGTTGGGAATGGTACATTTTTGTAAATCCACCCAGTGAACATGAAATTGTACATTGTGTATAATTGT TCATTAGAAAGGACAGTTTTACATGAATATTCATATATTTATTTTGTTTTAATTTGAATTGCCTGTTCAGGGTTCCTTATGCAGAGAAAT |
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FusionGenePPI for VPS13C_HERC1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| VPS13C | LGALS12, FAF2, UBXN4, DNAJC7, RNF19B, RAB9A, IER3IP1, VAPA, RAB1A, RAB30, FAM78B, HMGCLL1, LINC01587, ARPC5, VAPB | HERC1 | DFFA, PKM, EP300, ARF1, TSC2, CLTC, NOS2, SOX9, UBE2D3, BYSL, GRIPAP1, KCMF1, MYL12A, BAK1, BRCA1, MORC1, RSPH10B2, MLF1, ECHS1, RAPSN, DNM3, USP18, TFDP3, ARHGAP29, TTLL1, UNK, HERC2, HERC1, UBE2S, EGFR, SSH3, IFIT1B, WDFY3, TIGD6, CCDC65, GCNT3, TRPC4AP, CSNK1A1, NEUROG3, C1orf87, RAPGEF5, ZBBX, SMOX, TPTE2, ZNF610, FMO5, ZNF223, ZNF571, VPS36, ZNF555, RABGEF1, ZNF563, UBC |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for VPS13C_HERC1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for VPS13C_HERC1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | VPS13C | C4225186 | PARKINSON DISEASE 23, AUTOSOMAL RECESSIVE EARLY-ONSET | 1 | UNIPROT |
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