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Fusion gene ID: 41487 |
FusionGeneSummary for VMP1_C17orf64 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: VMP1_C17orf64 | Fusion gene ID: 41487 | Hgene | Tgene | Gene symbol | VMP1 | C17orf64 | Gene ID | 81671 | 124773 |
| Gene name | vacuole membrane protein 1 | chromosome 17 open reading frame 64 | |
| Synonyms | EPG3|TANGO5|TMEM49 | - | |
| Cytomap | 17q23.1 | 17q23.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | vacuole membrane protein 1ectopic P-granules autophagy protein 3 homologtransmembrane protein 49transport and golgi organization 5 homolog | uncharacterized protein C17orf64 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q96GC9 | Q86WR6 | |
| Ensembl transtripts involved in fusion gene | ENST00000262291, ENST00000537567, ENST00000539763, ENST00000536180, ENST00000545362, ENST00000588617, | ENST00000269127, | |
| Fusion gene scores | * DoF score | 19 X 10 X 9=1710 | 6 X 3 X 3=54 |
| # samples | 18 | 6 | |
| ** MAII score | log2(18/1710*10)=-3.24792751344359 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/54*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: VMP1 [Title/Abstract] AND C17orf64 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-AR-A24R-01A | VMP1 | chr17 | 57851246 | + | C17orf64 | chr17 | 58503144 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000262291 | ENST00000269127 | VMP1 | chr17 | 57851246 | + | C17orf64 | chr17 | 58503144 | + |
| In-frame | ENST00000537567 | ENST00000269127 | VMP1 | chr17 | 57851246 | + | C17orf64 | chr17 | 58503144 | + |
| In-frame | ENST00000539763 | ENST00000269127 | VMP1 | chr17 | 57851246 | + | C17orf64 | chr17 | 58503144 | + |
| In-frame | ENST00000536180 | ENST00000269127 | VMP1 | chr17 | 57851246 | + | C17orf64 | chr17 | 58503144 | + |
| In-frame | ENST00000545362 | ENST00000269127 | VMP1 | chr17 | 57851246 | + | C17orf64 | chr17 | 58503144 | + |
| intron-3CDS | ENST00000588617 | ENST00000269127 | VMP1 | chr17 | 57851246 | + | C17orf64 | chr17 | 58503144 | + |
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FusionProtFeatures for VMP1_C17orf64 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| VMP1 | C17orf64 |
| Stress-induced protein that, when overexpressed,promotes formation of intracellular vacuoles followed by celldeath. May be involved in the cytoplasmic vacuolization of acinarcells during the early stage of acute pancreatitis. Plays a rolein the initial stages of the autophagic process through itsinteraction with BECN1 (By similarity). Involved in cell-celladhesion. Plays an essential role in formation of cell junctions.{ECO:0000250, ECO:0000269|PubMed:17724469}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 2_43 | 238 | 407 | Topological domain | Cytoplasmic |
| Hgene | VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 65_77 | 238 | 407 | Topological domain | Extracellular |
| Hgene | VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 99_109 | 238 | 407 | Topological domain | Cytoplasmic |
| Hgene | VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 110_130 | 238 | 407 | Transmembrane | Helical |
| Hgene | VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 44_64 | 238 | 407 | Transmembrane | Helical |
| Hgene | VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 78_98 | 238 | 407 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 131_250 | 238 | 407 | Topological domain | Extracellular |
| Hgene | >VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 272_273 | 238 | 407 | Topological domain | Cytoplasmic |
| Hgene | >VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 295_305 | 238 | 407 | Topological domain | Extracellular |
| Hgene | >VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 327_363 | 238 | 407 | Topological domain | Cytoplasmic |
| Hgene | >VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 385_406 | 238 | 407 | Topological domain | Extracellular |
| Hgene | >VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 251_271 | 238 | 407 | Transmembrane | Helical |
| Hgene | >VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 274_294 | 238 | 407 | Transmembrane | Helical |
| Hgene | >VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 306_326 | 238 | 407 | Transmembrane | Helical |
| Hgene | >VMP1 | chr17:57851246 | chr17:58503144 | ENST00000262291 | + | 7 | 12 | 364_384 | 238 | 407 | Transmembrane | Helical |
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FusionGeneSequence for VMP1_C17orf64 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_VMP1_ENST00000262291_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_458aa MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLEILVILKEWTSKLWHRQSIVVSFLLLLAVLI ATYYVEGVHQQYVQRIEKQFLLYAYWIGLGILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISL WSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQVTNVSCLETSSSASPARDSLMRHAKGLDQDTF KTCKEYLRPLKKFLRKLHLPRDLPQKKKLKYMKQSLVVLGDHINTFLQHYCQAWEIKHWRKMLWRFISLFSELEAKQLRRLYKYTKSSQP AKFLVTFCASDAPERSLLADREDSLPKLCHAWGLHSNISGMKERLSNMQTPGQGSPLPGQPRSQDHVKKDSLRELSQKPKLKRKRIKEAP >In-frame_VMP1_ENST00000537567_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_324aa MDLKGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKVRIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEY QEFEEMLEHAESAQVTNVSCLETSSSASPARDSLMRHAKGLDQDTFKTCKEYLRPLKKFLRKLHLPRDLPQKKKLKYMKQSLVVLGDHIN TFLQHYCQAWEIKHWRKMLWRFISLFSELEAKQLRRLYKYTKSSQPAKFLVTFCASDAPERSLLADREDSLPKLCHAWGLHSNISGMKER >In-frame_VMP1_ENST00000539763_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_266aa MWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQVTNVSCLETSSSASPARDSLMRHAKGLDQDTFKTCKEYLRPLKK FLRKLHLPRDLPQKKKLKYMKQSLVVLGDHINTFLQHYCQAWEIKHWRKMLWRFISLFSELEAKQLRRLYKYTKSSQPAKFLVTFCASDA >In-frame_VMP1_ENST00000536180_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_361aa MDLKYVQRIEKQFLLYAYWIGLGILSSVGLGTGLHTFLLYLGPHIASVTLAAYECNSVNFPEPPYPDQIICPDEEGTEGTISLWSIISKV RIEACMWGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAESAQVTNVSCLETSSSASPARDSLMRHAKGLDQDTFKTCKEYL RPLKKFLRKLHLPRDLPQKKKLKYMKQSLVVLGDHINTFLQHYCQAWEIKHWRKMLWRFISLFSELEAKQLRRLYKYTKSSQPAKFLVTF CASDAPERSLLADREDSLPKLCHAWGLHSNISGMKERLSNMQTPGQGSPLPGQPRSQDHVKKDSLRELSQKPKLKRKRIKEAPETPETEP >In-frame_VMP1_ENST00000545362_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_402aa MAENGKNCDQRRVAMNKEHHNGNFTDPSSVNEKKRREREERQNIVLWRQPLITLQYFSLEILVILKEWTSKLWHRQSIVVSFLLLLAVLI ATYYVEGVHQQYVQRIEKQFLLYAYWIGLGILSSVGLGTGLHTFLLYLGIGTAIGELPPYFMARAARLSGAEPDDEEYQEFEEMLEHAES AQVTNVSCLETSSSASPARDSLMRHAKGLDQDTFKTCKEYLRPLKKFLRKLHLPRDLPQKKKLKYMKQSLVVLGDHINTFLQHYCQAWEI KHWRKMLWRFISLFSELEAKQLRRLYKYTKSSQPAKFLVTFCASDAPERSLLADREDSLPKLCHAWGLHSNISGMKERLSNMQTPGQGSP |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_VMP1_ENST00000262291_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_1374nt ATGGCAGAGAATGGAAAAAATTGTGACCAGAGACGTGTAGCAATGAACAAGGAACATCATAATGGAAATTTCACAGACCCCTCTTCAGTG AATGAAAAGAAGAGGAGGGAGCGGGAAGAAAGGCAGAATATTGTCCTGTGGAGACAGCCGCTCATTACCTTGCAGTATTTTTCTCTGGAA ATCCTTGTAATCTTGAAGGAATGGACCTCAAAATTATGGCATCGTCAAAGCATTGTGGTGTCTTTTTTACTGCTGCTTGCTGTGCTTATA GCTACGTATTATGTTGAAGGAGTGCATCAACAGTATGTGCAACGTATAGAGAAACAGTTTCTTTTGTATGCCTACTGGATAGGCTTAGGA ATTTTGTCTTCTGTTGGGCTTGGAACAGGGCTGCACACCTTTCTGCTTTATCTGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTAT GAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTG TGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGA GCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGTGACA AATGTGTCATGCCTGGAGACAAGCTCCAGCGCCAGCCCTGCTAGAGACTCGCTCATGCGCCATGCCAAGGGCCTGGATCAGGACACCTTC AAAACTTGTAAAGAATACCTAAGACCGCTGAAGAAGTTCCTGCGAAAGTTGCACCTGCCCAGGGACCTTCCCCAGAAGAAGAAGCTGAAG TACATGAAGCAGAGCCTTGTGGTCCTAGGGGACCACATCAACACCTTTCTGCAGCATTACTGCCAAGCCTGGGAAATCAAACACTGGAGA AAGATGCTCTGGCGGTTCATCTCCCTCTTCTCGGAGCTGGAAGCAAAGCAGCTTCGCCGACTTTACAAGTACACCAAGAGCAGCCAGCCG GCCAAGTTCCTGGTGACATTCTGCGCCTCGGATGCGCCGGAGAGGTCCTTGCTGGCCGACCGGGAAGACAGTCTGCCCAAGCTCTGCCAT GCATGGGGGCTGCACAGCAACATCAGCGGCATGAAGGAGCGGCTGTCCAACATGCAGACCCCAGGTCAAGGGAGCCCCCTGCCTGGGCAG CCAAGATCCCAGGACCATGTCAAGAAAGATTCTTTAAGGGAGCTTTCTCAAAAACCAAAACTCAAGAGGAAGAGGATAAAGGAAGCCCCA >In-frame_VMP1_ENST00000537567_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_972nt ATGGACCTCAAAGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGAT CAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGG GGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTAT CAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGTGACAAATGTGTCATGCCTGGAGACAAGCTCCAGCGCCAGCCCTGCT AGAGACTCGCTCATGCGCCATGCCAAGGGCCTGGATCAGGACACCTTCAAAACTTGTAAAGAATACCTAAGACCGCTGAAGAAGTTCCTG CGAAAGTTGCACCTGCCCAGGGACCTTCCCCAGAAGAAGAAGCTGAAGTACATGAAGCAGAGCCTTGTGGTCCTAGGGGACCACATCAAC ACCTTTCTGCAGCATTACTGCCAAGCCTGGGAAATCAAACACTGGAGAAAGATGCTCTGGCGGTTCATCTCCCTCTTCTCGGAGCTGGAA GCAAAGCAGCTTCGCCGACTTTACAAGTACACCAAGAGCAGCCAGCCGGCCAAGTTCCTGGTGACATTCTGCGCCTCGGATGCGCCGGAG AGGTCCTTGCTGGCCGACCGGGAAGACAGTCTGCCCAAGCTCTGCCATGCATGGGGGCTGCACAGCAACATCAGCGGCATGAAGGAGCGG CTGTCCAACATGCAGACCCCAGGTCAAGGGAGCCCCCTGCCTGGGCAGCCAAGATCCCAGGACCATGTCAAGAAAGATTCTTTAAGGGAG >In-frame_VMP1_ENST00000539763_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_798nt ATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAA GAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGTGACAAATGTGTCATGCCTGGAGACAAGCTCCAGCGCCAGC CCTGCTAGAGACTCGCTCATGCGCCATGCCAAGGGCCTGGATCAGGACACCTTCAAAACTTGTAAAGAATACCTAAGACCGCTGAAGAAG TTCCTGCGAAAGTTGCACCTGCCCAGGGACCTTCCCCAGAAGAAGAAGCTGAAGTACATGAAGCAGAGCCTTGTGGTCCTAGGGGACCAC ATCAACACCTTTCTGCAGCATTACTGCCAAGCCTGGGAAATCAAACACTGGAGAAAGATGCTCTGGCGGTTCATCTCCCTCTTCTCGGAG CTGGAAGCAAAGCAGCTTCGCCGACTTTACAAGTACACCAAGAGCAGCCAGCCGGCCAAGTTCCTGGTGACATTCTGCGCCTCGGATGCG CCGGAGAGGTCCTTGCTGGCCGACCGGGAAGACAGTCTGCCCAAGCTCTGCCATGCATGGGGGCTGCACAGCAACATCAGCGGCATGAAG GAGCGGCTGTCCAACATGCAGACCCCAGGTCAAGGGAGCCCCCTGCCTGGGCAGCCAAGATCCCAGGACCATGTCAAGAAAGATTCTTTA >In-frame_VMP1_ENST00000536180_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_1083nt ATGGACCTCAAATATGTGCAACGTATAGAGAAACAGTTTCTTTTGTATGCCTACTGGATAGGCTTAGGAATTTTGTCTTCTGTTGGGCTT GGAACAGGGCTGCACACCTTTCTGCTTTATCTGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTT CCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTT AGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCT GAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGTGACAAATGTGTCATGCCTGGAGACA AGCTCCAGCGCCAGCCCTGCTAGAGACTCGCTCATGCGCCATGCCAAGGGCCTGGATCAGGACACCTTCAAAACTTGTAAAGAATACCTA AGACCGCTGAAGAAGTTCCTGCGAAAGTTGCACCTGCCCAGGGACCTTCCCCAGAAGAAGAAGCTGAAGTACATGAAGCAGAGCCTTGTG GTCCTAGGGGACCACATCAACACCTTTCTGCAGCATTACTGCCAAGCCTGGGAAATCAAACACTGGAGAAAGATGCTCTGGCGGTTCATC TCCCTCTTCTCGGAGCTGGAAGCAAAGCAGCTTCGCCGACTTTACAAGTACACCAAGAGCAGCCAGCCGGCCAAGTTCCTGGTGACATTC TGCGCCTCGGATGCGCCGGAGAGGTCCTTGCTGGCCGACCGGGAAGACAGTCTGCCCAAGCTCTGCCATGCATGGGGGCTGCACAGCAAC ATCAGCGGCATGAAGGAGCGGCTGTCCAACATGCAGACCCCAGGTCAAGGGAGCCCCCTGCCTGGGCAGCCAAGATCCCAGGACCATGTC AAGAAAGATTCTTTAAGGGAGCTTTCTCAAAAACCAAAACTCAAGAGGAAGAGGATAAAGGAAGCCCCAGAAACTCCAGAGACTGAACCG >In-frame_VMP1_ENST00000545362_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_1206nt ATGGCAGAGAATGGAAAAAATTGTGACCAGAGACGTGTAGCAATGAACAAGGAACATCATAATGGAAATTTCACAGACCCCTCTTCAGTG AATGAAAAGAAGAGGAGGGAGCGGGAAGAAAGGCAGAATATTGTCCTGTGGAGACAGCCGCTCATTACCTTGCAGTATTTTTCTCTGGAA ATCCTTGTAATCTTGAAGGAATGGACCTCAAAATTATGGCATCGTCAAAGCATTGTGGTGTCTTTTTTACTGCTGCTTGCTGTGCTTATA GCTACGTATTATGTTGAAGGAGTGCATCAACAGTATGTGCAACGTATAGAGAAACAGTTTCTTTTGTATGCCTACTGGATAGGCTTAGGA ATTTTGTCTTCTGTTGGGCTTGGAACAGGGCTGCACACCTTTCTGCTTTATCTGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATAT TTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCT GCACAAGTGACAAATGTGTCATGCCTGGAGACAAGCTCCAGCGCCAGCCCTGCTAGAGACTCGCTCATGCGCCATGCCAAGGGCCTGGAT CAGGACACCTTCAAAACTTGTAAAGAATACCTAAGACCGCTGAAGAAGTTCCTGCGAAAGTTGCACCTGCCCAGGGACCTTCCCCAGAAG AAGAAGCTGAAGTACATGAAGCAGAGCCTTGTGGTCCTAGGGGACCACATCAACACCTTTCTGCAGCATTACTGCCAAGCCTGGGAAATC AAACACTGGAGAAAGATGCTCTGGCGGTTCATCTCCCTCTTCTCGGAGCTGGAAGCAAAGCAGCTTCGCCGACTTTACAAGTACACCAAG AGCAGCCAGCCGGCCAAGTTCCTGGTGACATTCTGCGCCTCGGATGCGCCGGAGAGGTCCTTGCTGGCCGACCGGGAAGACAGTCTGCCC AAGCTCTGCCATGCATGGGGGCTGCACAGCAACATCAGCGGCATGAAGGAGCGGCTGTCCAACATGCAGACCCCAGGTCAAGGGAGCCCC CTGCCTGGGCAGCCAAGATCCCAGGACCATGTCAAGAAAGATTCTTTAAGGGAGCTTTCTCAAAAACCAAAACTCAAGAGGAAGAGGATA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_VMP1_ENST00000262291_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_1839nt GACAAGTTCCGGATCAAGAATCACAAAGCGAGCAGTCATTCTTCCTCTTGCCACACCCACAGGGCCCGCACTAAGAGCCTAACTGAAATC CCGCGAGGATCAACCGAGCTCGCCGAAAGGAGGGAGGAACGTATCCCTTCTGGAGGCTGTCTCAGGGGGCAGAGGGACCGGACCGGAAGT GACGTGAGCGGGTTCCGGTTGTCTGGAGCCCAGCGGCGGGTGTGAGAGTCCGTAAGGAGCAGCTTCCAGGATCCTGAGATCCGGAGCAGC CGGGGTCGGAGCGGCTCCTCAAGAGTTACTGATCTATGAAATGGCAGAGAATGGAAAAAATTGTGACCAGAGACGTGTAGCAATGAACAA GGAACATCATAATGGAAATTTCACAGACCCCTCTTCAGTGAATGAAAAGAAGAGGAGGGAGCGGGAAGAAAGGCAGAATATTGTCCTGTG GAGACAGCCGCTCATTACCTTGCAGTATTTTTCTCTGGAAATCCTTGTAATCTTGAAGGAATGGACCTCAAAATTATGGCATCGTCAAAG CATTGTGGTGTCTTTTTTACTGCTGCTTGCTGTGCTTATAGCTACGTATTATGTTGAAGGAGTGCATCAACAGTATGTGCAACGTATAGA GAAACAGTTTCTTTTGTATGCCTACTGGATAGGCTTAGGAATTTTGTCTTCTGTTGGGCTTGGAACAGGGCTGCACACCTTTCTGCTTTA TCTGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTAT TTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGG TACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATT TGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGTGACAAATGTGTCATGCCTGGAGACAAGCTCCAGCGCCAGCCCTGCTAGAGACTC GCTCATGCGCCATGCCAAGGGCCTGGATCAGGACACCTTCAAAACTTGTAAAGAATACCTAAGACCGCTGAAGAAGTTCCTGCGAAAGTT GCACCTGCCCAGGGACCTTCCCCAGAAGAAGAAGCTGAAGTACATGAAGCAGAGCCTTGTGGTCCTAGGGGACCACATCAACACCTTTCT GCAGCATTACTGCCAAGCCTGGGAAATCAAACACTGGAGAAAGATGCTCTGGCGGTTCATCTCCCTCTTCTCGGAGCTGGAAGCAAAGCA GCTTCGCCGACTTTACAAGTACACCAAGAGCAGCCAGCCGGCCAAGTTCCTGGTGACATTCTGCGCCTCGGATGCGCCGGAGAGGTCCTT GCTGGCCGACCGGGAAGACAGTCTGCCCAAGCTCTGCCATGCATGGGGGCTGCACAGCAACATCAGCGGCATGAAGGAGCGGCTGTCCAA CATGCAGACCCCAGGTCAAGGGAGCCCCCTGCCTGGGCAGCCAAGATCCCAGGACCATGTCAAGAAAGATTCTTTAAGGGAGCTTTCTCA AAAACCAAAACTCAAGAGGAAGAGGATAAAGGAAGCCCCAGAAACTCCAGAGACTGAACCGTAAGAAGACCAACTGGGACAAAGGGCCCG CTTGTCCTGGCTCTCAGAGCACGGGGAATGGAGACCAAAAAGGGAAAAGAATTGTCCTTATCAAAAAGATTCTCAGGTCTTAATTAGGAA >In-frame_VMP1_ENST00000537567_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_1454nt GTGAGCGGGTTCCGGTTGTCTGGAGCCCAGCGGCGGGTGTGAGAGTCCGTAAGGAGCAGCTTCCAGGATCCTGAGATCCGGAGCAGCCGG GGTCGGAGCGGCTCCTCAAGAGTTACTGATCTATGAAATGGCAGAGAATGGAAAAAATTGTGACCAGAGACGTGTAGCAATGAACAAGGA ACATCATAATGGAAATTTCACAGACCCCTCTTCAGTGAATGAAAAGAAGAGGAGGGAGCGGGAAGAAAGGCAGAATATTGTCCTGTGGAG ACAGCCGCTCATTACCTTGCAGTATTTTTCTCTGGAAATCCTTGTAATCTTGAAGGAATGGACCTCAAAGGTCCACATATAGCCTCAGTT ACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAA GGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCA TATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAG TCTGCACAAGTGACAAATGTGTCATGCCTGGAGACAAGCTCCAGCGCCAGCCCTGCTAGAGACTCGCTCATGCGCCATGCCAAGGGCCTG GATCAGGACACCTTCAAAACTTGTAAAGAATACCTAAGACCGCTGAAGAAGTTCCTGCGAAAGTTGCACCTGCCCAGGGACCTTCCCCAG AAGAAGAAGCTGAAGTACATGAAGCAGAGCCTTGTGGTCCTAGGGGACCACATCAACACCTTTCTGCAGCATTACTGCCAAGCCTGGGAA ATCAAACACTGGAGAAAGATGCTCTGGCGGTTCATCTCCCTCTTCTCGGAGCTGGAAGCAAAGCAGCTTCGCCGACTTTACAAGTACACC AAGAGCAGCCAGCCGGCCAAGTTCCTGGTGACATTCTGCGCCTCGGATGCGCCGGAGAGGTCCTTGCTGGCCGACCGGGAAGACAGTCTG CCCAAGCTCTGCCATGCATGGGGGCTGCACAGCAACATCAGCGGCATGAAGGAGCGGCTGTCCAACATGCAGACCCCAGGTCAAGGGAGC CCCCTGCCTGGGCAGCCAAGATCCCAGGACCATGTCAAGAAAGATTCTTTAAGGGAGCTTTCTCAAAAACCAAAACTCAAGAGGAAGAGG ATAAAGGAAGCCCCAGAAACTCCAGAGACTGAACCGTAAGAAGACCAACTGGGACAAAGGGCCCGCTTGTCCTGGCTCTCAGAGCACGGG GAATGGAGACCAAAAAGGGAAAAGAATTGTCCTTATCAAAAAGATTCTCAGGTCTTAATTAGGAATAAATGAGGTGGGAAATAAACATTC >In-frame_VMP1_ENST00000539763_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_1518nt GAGCGGGTTCCGGTTGTCTGGAGCCCAGCGGCGGGTGTGAGAGTCCGTAAGGAGCAGCTTCCAGGATCCTGAGATCCGGAGCAGCCGGGG TCGGAGCGGCTCCTCAAGAGTTACTGATCTATGAAATGGCAGAGAATGGAAAAAATTGTGACCAGAGACGTGTAGCAATGAACAAGGAAC ATCATAATGGAAATTTCACAGATTATGGCATCGTCAAAGCATTGTGGTGTCTTTTTTACTGCTGCTTGCTGTGCTTATAGCTACGTATTA TGTTGAAGGAGTGCATCAACAGTATGTGCAACGTATAGAGAAACAGTTTCTTTTGTATGCCTACTGGATAGGCTTAGGAATTTTGTCTTC TGTTGGGCTTGGAACAGGGCTGCACACCTTTCTGCTTTATCTGGGTCCACATATAGCCTCAGTTACATTAGCTGCTTATGAATGCAATTC AGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCACTGAAGGAACCATTTCTTTGTGGAGTATCAT CTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCT CTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGTGACAAATGTGTCATG CCTGGAGACAAGCTCCAGCGCCAGCCCTGCTAGAGACTCGCTCATGCGCCATGCCAAGGGCCTGGATCAGGACACCTTCAAAACTTGTAA AGAATACCTAAGACCGCTGAAGAAGTTCCTGCGAAAGTTGCACCTGCCCAGGGACCTTCCCCAGAAGAAGAAGCTGAAGTACATGAAGCA GAGCCTTGTGGTCCTAGGGGACCACATCAACACCTTTCTGCAGCATTACTGCCAAGCCTGGGAAATCAAACACTGGAGAAAGATGCTCTG GCGGTTCATCTCCCTCTTCTCGGAGCTGGAAGCAAAGCAGCTTCGCCGACTTTACAAGTACACCAAGAGCAGCCAGCCGGCCAAGTTCCT GGTGACATTCTGCGCCTCGGATGCGCCGGAGAGGTCCTTGCTGGCCGACCGGGAAGACAGTCTGCCCAAGCTCTGCCATGCATGGGGGCT GCACAGCAACATCAGCGGCATGAAGGAGCGGCTGTCCAACATGCAGACCCCAGGTCAAGGGAGCCCCCTGCCTGGGCAGCCAAGATCCCA GGACCATGTCAAGAAAGATTCTTTAAGGGAGCTTTCTCAAAAACCAAAACTCAAGAGGAAGAGGATAAAGGAAGCCCCAGAAACTCCAGA GACTGAACCGTAAGAAGACCAACTGGGACAAAGGGCCCGCTTGTCCTGGCTCTCAGAGCACGGGGAATGGAGACCAAAAAGGGAAAAGAA >In-frame_VMP1_ENST00000536180_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_1548nt GTCTGGAGCCCAGCGGCGGGTGTGAGAGTCCGTAAGGAGCAGCTTCCAGGATCCTGAGATCCGGAGCAGCCGGGGTCGGAGCGGCTCCTC AAGAGTTACTGATCTATGAAATGGCAGAGAATGGAAAAAATTGTGACCAGAGACGTGTAGCAATGAACAAGGAACATCATAATGGAAATT TCACAGACCCCTCTTCAGTGAATGAAAAGAAGAGGAGGGAGCGGGAAGAAAGGCAGAATATTGTCCTGTGGAGACAGCCGCTCATTACCT TGCAGTATTTTTCTCTGGAAATCCTTGTAATCTTGAAGGAATGGACCTCAAATATGTGCAACGTATAGAGAAACAGTTTCTTTTGTATGC CTACTGGATAGGCTTAGGAATTTTGTCTTCTGTTGGGCTTGGAACAGGGCTGCACACCTTTCTGCTTTATCTGGGTCCACATATAGCCTC AGTTACATTAGCTGCTTATGAATGCAATTCAGTTAATTTTCCCGAACCACCCTATCCTGATCAGATTATTTGTCCAGATGAAGAGGGCAC TGAAGGAACCATTTCTTTGTGGAGTATCATCTCAAAAGTTAGGATTGAAGCCTGCATGTGGGGTATCGGTACAGCAATCGGAGAGCTGCC TCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAACCAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGC AGAGTCTGCACAAGTGACAAATGTGTCATGCCTGGAGACAAGCTCCAGCGCCAGCCCTGCTAGAGACTCGCTCATGCGCCATGCCAAGGG CCTGGATCAGGACACCTTCAAAACTTGTAAAGAATACCTAAGACCGCTGAAGAAGTTCCTGCGAAAGTTGCACCTGCCCAGGGACCTTCC CCAGAAGAAGAAGCTGAAGTACATGAAGCAGAGCCTTGTGGTCCTAGGGGACCACATCAACACCTTTCTGCAGCATTACTGCCAAGCCTG GGAAATCAAACACTGGAGAAAGATGCTCTGGCGGTTCATCTCCCTCTTCTCGGAGCTGGAAGCAAAGCAGCTTCGCCGACTTTACAAGTA CACCAAGAGCAGCCAGCCGGCCAAGTTCCTGGTGACATTCTGCGCCTCGGATGCGCCGGAGAGGTCCTTGCTGGCCGACCGGGAAGACAG TCTGCCCAAGCTCTGCCATGCATGGGGGCTGCACAGCAACATCAGCGGCATGAAGGAGCGGCTGTCCAACATGCAGACCCCAGGTCAAGG GAGCCCCCTGCCTGGGCAGCCAAGATCCCAGGACCATGTCAAGAAAGATTCTTTAAGGGAGCTTTCTCAAAAACCAAAACTCAAGAGGAA GAGGATAAAGGAAGCCCCAGAAACTCCAGAGACTGAACCGTAAGAAGACCAACTGGGACAAAGGGCCCGCTTGTCCTGGCTCTCAGAGCA CGGGGAATGGAGACCAAAAAGGGAAAAGAATTGTCCTTATCAAAAAGATTCTCAGGTCTTAATTAGGAATAAATGAGGTGGGAAATAAAC >In-frame_VMP1_ENST00000545362_chr17_57851246_+_C17orf64_ENST00000269127_chr17_58503144_+_1414nt GATCCGGAGCAGCCGGGGTCGGAGCGGCTCCTCAAGAGTTACTGATCTATGAAATGGCAGAGAATGGAAAAAATTGTGACCAGAGACGTG TAGCAATGAACAAGGAACATCATAATGGAAATTTCACAGACCCCTCTTCAGTGAATGAAAAGAAGAGGAGGGAGCGGGAAGAAAGGCAGA ATATTGTCCTGTGGAGACAGCCGCTCATTACCTTGCAGTATTTTTCTCTGGAAATCCTTGTAATCTTGAAGGAATGGACCTCAAAATTAT GGCATCGTCAAAGCATTGTGGTGTCTTTTTTACTGCTGCTTGCTGTGCTTATAGCTACGTATTATGTTGAAGGAGTGCATCAACAGTATG TGCAACGTATAGAGAAACAGTTTCTTTTGTATGCCTACTGGATAGGCTTAGGAATTTTGTCTTCTGTTGGGCTTGGAACAGGGCTGCACA CCTTTCTGCTTTATCTGGGTATCGGTACAGCAATCGGAGAGCTGCCTCCATATTTCATGGCCAGAGCAGCTCGCCTCTCAGGTGCTGAAC CAGATGATGAAGAGTATCAGGAATTTGAAGAGATGCTGGAACATGCAGAGTCTGCACAAGTGACAAATGTGTCATGCCTGGAGACAAGCT CCAGCGCCAGCCCTGCTAGAGACTCGCTCATGCGCCATGCCAAGGGCCTGGATCAGGACACCTTCAAAACTTGTAAAGAATACCTAAGAC CGCTGAAGAAGTTCCTGCGAAAGTTGCACCTGCCCAGGGACCTTCCCCAGAAGAAGAAGCTGAAGTACATGAAGCAGAGCCTTGTGGTCC TAGGGGACCACATCAACACCTTTCTGCAGCATTACTGCCAAGCCTGGGAAATCAAACACTGGAGAAAGATGCTCTGGCGGTTCATCTCCC TCTTCTCGGAGCTGGAAGCAAAGCAGCTTCGCCGACTTTACAAGTACACCAAGAGCAGCCAGCCGGCCAAGTTCCTGGTGACATTCTGCG CCTCGGATGCGCCGGAGAGGTCCTTGCTGGCCGACCGGGAAGACAGTCTGCCCAAGCTCTGCCATGCATGGGGGCTGCACAGCAACATCA GCGGCATGAAGGAGCGGCTGTCCAACATGCAGACCCCAGGTCAAGGGAGCCCCCTGCCTGGGCAGCCAAGATCCCAGGACCATGTCAAGA AAGATTCTTTAAGGGAGCTTTCTCAAAAACCAAAACTCAAGAGGAAGAGGATAAAGGAAGCCCCAGAAACTCCAGAGACTGAACCGTAAG AAGACCAACTGGGACAAAGGGCCCGCTTGTCCTGGCTCTCAGAGCACGGGGAATGGAGACCAAAAAGGGAAAAGAATTGTCCTTATCAAA |
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FusionGenePPI for VMP1_C17orf64 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| VMP1 | HGS, ELAVL1, TJP1, KLK11, LPAR6, ERGIC3, FAF2, KRAS, TCTN2, TCTN3, TMEM216, DPEP1, CDH13, MAS1, LMNA | C17orf64 | DUSP12 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for VMP1_C17orf64 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for VMP1_C17orf64 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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