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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 41053

FusionGeneSummary for USP32_GPR137

check button Fusion gene summary
Fusion gene informationFusion gene name: USP32_GPR137
Fusion gene ID: 41053
HgeneTgene
Gene symbol

USP32

GPR137

Gene ID

84669

56834

Gene nameubiquitin specific peptidase 32G protein-coupled receptor 137
SynonymsNY-REN-60|USP10C11orf4|GPR137A|TM7SF1L1
Cytomap

17q23.1-q23.2

11q13.1

Type of geneprotein-codingprotein-coding
Descriptionubiquitin carboxyl-terminal hydrolase 32deubiquitinating enzyme 32renal carcinoma antigen NY-REN-60ubiquitin specific protease 32ubiquitin thioesterase 32ubiquitin thiolesterase 32ubiquitin-specific-processing protease 32integral membrane protein GPR137transmembrane 7 superfamily member 1-like 1 protein
Modification date2018052320180519
UniProtAcc

Q8NFA0

Q96N19

Ensembl transtripts involved in fusion geneENST00000300896, ENST00000592339, 
ENST00000393003, ENST00000586881, 
ENST00000411458, ENST00000539851, 
ENST00000377702, ENST00000438980, 
ENST00000313074, 
Fusion gene scores* DoF score28 X 15 X 9=37804 X 3 X 4=48
# samples 274
** MAII scorelog2(27/3780*10)=-3.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: USP32 [Title/Abstract] AND GPR137 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDBRCATCGA-AC-A23H-01AUSP32chr17

58469243

-GPR137chr11

64053982

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000300896ENST00000411458USP32chr17

58469243

-GPR137chr11

64053982

+
5CDS-5UTRENST00000300896ENST00000539851USP32chr17

58469243

-GPR137chr11

64053982

+
5CDS-5UTRENST00000300896ENST00000377702USP32chr17

58469243

-GPR137chr11

64053982

+
5CDS-5UTRENST00000300896ENST00000438980USP32chr17

58469243

-GPR137chr11

64053982

+
5CDS-5UTRENST00000300896ENST00000313074USP32chr17

58469243

-GPR137chr11

64053982

+
intron-3CDSENST00000592339ENST00000411458USP32chr17

58469243

-GPR137chr11

64053982

+
intron-5UTRENST00000592339ENST00000539851USP32chr17

58469243

-GPR137chr11

64053982

+
intron-5UTRENST00000592339ENST00000377702USP32chr17

58469243

-GPR137chr11

64053982

+
intron-5UTRENST00000592339ENST00000438980USP32chr17

58469243

-GPR137chr11

64053982

+
intron-5UTRENST00000592339ENST00000313074USP32chr17

58469243

-GPR137chr11

64053982

+
In-frameENST00000393003ENST00000411458USP32chr17

58469243

-GPR137chr11

64053982

+
5CDS-5UTRENST00000393003ENST00000539851USP32chr17

58469243

-GPR137chr11

64053982

+
5CDS-5UTRENST00000393003ENST00000377702USP32chr17

58469243

-GPR137chr11

64053982

+
5CDS-5UTRENST00000393003ENST00000438980USP32chr17

58469243

-GPR137chr11

64053982

+
5CDS-5UTRENST00000393003ENST00000313074USP32chr17

58469243

-GPR137chr11

64053982

+
intron-3CDSENST00000586881ENST00000411458USP32chr17

58469243

-GPR137chr11

64053982

+
intron-5UTRENST00000586881ENST00000539851USP32chr17

58469243

-GPR137chr11

64053982

+
intron-5UTRENST00000586881ENST00000377702USP32chr17

58469243

-GPR137chr11

64053982

+
intron-5UTRENST00000586881ENST00000438980USP32chr17

58469243

-GPR137chr11

64053982

+
intron-5UTRENST00000586881ENST00000313074USP32chr17

58469243

-GPR137chr11

64053982

+

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FusionProtFeatures for USP32_GPR137


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
USP32

Q8NFA0

GPR137

Q96N19


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+07111_140-35418Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+07162_175-35418Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+07197_218-35418Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+071_31-35418Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+07242_274-35418Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+07296_417-35418Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+0753_60-35418Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+0782_89-35418Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+07111_140-5347Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+07162_175-5347Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+07197_218-5347Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+071_31-5347Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+07242_274-5347Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+07296_417-5347Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+0753_60-5347Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+0782_89-5347Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+19111_14053476Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+19162_17553476Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+19197_21853476Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+19242_27453476Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+19296_41753476Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+1953_6053476Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+1982_8953476Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+07111_140-36397Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+07162_175-36397Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+07197_218-36397Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+071_31-36397Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+07242_274-36397Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+07296_417-36397Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+0753_60-36397Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+0782_89-36397Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+07111_140-5321Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+07162_175-5321Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+07197_218-5321Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+071_31-5321Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+07242_274-5321Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+07296_417-5321Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+0753_60-5321Topological domainCytoplasmic
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+0782_89-5321Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+07141_161-35418TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+07176_196-35418TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+07219_241-35418TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+07275_295-35418TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+0732_52-35418TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+0761_81-35418TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000313074+0790_110-35418TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+07141_161-5347TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+07176_196-5347TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+07219_241-5347TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+07275_295-5347TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+0732_52-5347TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+0761_81-5347TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000377702+0790_110-5347TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+19141_16153476TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+19176_19653476TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+19219_24153476TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+19275_29553476TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+1961_8153476TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+1990_11053476TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+07141_161-36397TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+07176_196-36397TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+07219_241-36397TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+07275_295-36397TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+0732_52-36397TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+0761_81-36397TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000438980+0790_110-36397TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+07141_161-5321TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+07176_196-5321TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+07219_241-5321TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+07275_295-5321TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+0732_52-5321TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+0761_81-5321TransmembraneHelical
TgeneGPR137chr17:58469243chr11:64053982ENST00000539851+0790_110-5321TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneUSP32chr17:58469243chr11:64053982ENST00000300896-134241_252191605Calcium binding1
HgeneUSP32chr17:58469243chr11:64053982ENST00000300896-134277_288191605Calcium binding2
HgeneUSP32chr17:58469243chr11:64053982ENST00000300896-134228_263191605DomainEF-hand 2
HgeneUSP32chr17:58469243chr11:64053982ENST00000300896-134264_299191605DomainEF-hand 3
HgeneUSP32chr17:58469243chr11:64053982ENST00000300896-134369_585191605DomainDUSP
HgeneUSP32chr17:58469243chr11:64053982ENST00000300896-134734_1567191605DomainNote=USP
HgeneUSP32chr17:58469243chr11:64053982ENST00000300896-13491_126191605DomainEF-hand 1
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+191_3153476Topological domainExtracellular
TgeneGPR137chr17:58469243chr11:64053982ENST00000411458+1932_5253476TransmembraneHelical


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FusionGeneSequence for USP32_GPR137


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_USP32_ENST00000300896_chr17_58469243_-_GPR137_ENST00000411458_chr11_64053982_+_442aa
MGAKESRIGFLSYEEALRRGLPPXHGEXPVWPGACCRAGACAATCCDPGADSCLHHPVCPALLLRLCPALAGASVWAQASQLSDGVPGPL
SALGRLAYHPLLLLLPRYSPRQPPGALALLASLLLPRLPAVLHLDAYEPLLCPGGVQGQGEASAGDEPRLARCPRGLCGGLAALSAGERA
VCCALPSAPGTALGPAACPRPGERLPVRHLRAVSCCLPLPRRQAGALHXHLPGGQGDQCVPGGRDGWRHGPALCQPGLLQPDSTGLGPPE
PAGHLRLRLVQCVXPGGPGEXPGEQRLPGIWPHPLRVGATAHHPAGGLLPGAPAPTGPEHQPHPQWAGLCLSVLLLXPGWALXRXGLLLG

>In-frame_USP32_ENST00000393003_chr17_58469243_-_GPR137_ENST00000411458_chr11_64053982_+_442aa
MGAKESRIGFLSYEEALRRGLPPXHGEXPVWPGACCRAGACAATCCDPGADSCLHHPVCPALLLRLCPALAGASVWAQASQLSDGVPGPL
SALGRLAYHPLLLLLPRYSPRQPPGALALLASLLLPRLPAVLHLDAYEPLLCPGGVQGQGEASAGDEPRLARCPRGLCGGLAALSAGERA
VCCALPSAPGTALGPAACPRPGERLPVRHLRAVSCCLPLPRRQAGALHXHLPGGQGDQCVPGGRDGWRHGPALCQPGLLQPDSTGLGPPE
PAGHLRLRLVQCVXPGGPGEXPGEQRLPGIWPHPLRVGATAHHPAGGLLPGAPAPTGPEHQPHPQWAGLCLSVLLLXPGWALXRXGLLLG


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_USP32_ENST00000300896_chr17_58469243_-_GPR137_ENST00000411458_chr11_64053982_+_1327nt
ATGGGTGCCAAGGAGTCACGGATCGGATTCCTCAGCTACGAGGAGGCGCTGAGGAGAGGCCTCCCTCCCTGACATGGAGAGTAACCTGTC
TGGCCTGGTGCCTGCTGCCGGGCTGGTGCCTGCGCTGCCACCTGCTGTGACCCTGGGGCTGACAGCTGCCTACACCACCCTGTATGCCCT
GCTCTTCTTCTCCGTCTATGCCCAGCTCTGGCTGGTGCTTCTGTATGGGCACAAGCGTCTCAGCTATCAGACGGTGTTCCTGGCCCTCTG
TCTGCTCTGGGCCGCCTTGCGTACCACCCTCTTCTCCTTCTACTTCCGAGATACTCCCCGCGCCAACCGCCTGGGGCCCTTGCCCTTCTG
GCTTCTCTACTGCTGCCCCGTCTGCCTGCAGTTCTTCACCTTGACGCTTATGAACCTCTACTTTGCCCAGGTGGTGTTCAAGGCCAAGGT
GAAGCGTCGGCCGGAGATGAGCCGAGGCTTGCTCGCTGTCCGAGGGGCCTTTGTGGGGGCCTCGCTGCTCTTTCTGCTGGTGAACGTGCT
GTGTGCTGTGCTCTCCCATCGGCGCCGGGCACAGCCCTGGGCCCTGCTGCTTGTCCGCGTCCTGGTGAGCGACTCCCTGTTCGTCATCTG
CGCGCTGTCTCTTGCTGCCTGCCTCTGCCTCGTCGCCAGGCGGGCGCCCTCCACTAGCATCTACCTGGAGGCCAAGGGGACCAGTGTGTG
CCAGGCGGCCGCGATGGGTGGCGCCATGGTCCTGCTCTATGCCAGCCGGGCCTGCTACAACCTGACAGCACTGGCCTTGGCCCCCCAGAG
CCGGCTGGACACCTTCGATTACGACTGGTACAATGTGTCTGACCAGGCGGACCTGGTGAATGACCTGGGGAACAAAGGCTACCTGGTATT
TGGCCTCATCCTCTTCGTGTGGGAGCTACTGCCCACCACCCTGCTGGTGGGCTTCTTCCGGGTGCACCGGCCCCCACAGGACCTGAGCAC
CAGCCACATCCTCAATGGGCAGGTCTTTGCCTCTCGGTCCTACTTCTTTGACCGGGCTGGGCACTGTGAAGATGAGGGCTGCTCCTGGGA
GCACAGCCGGGGTGAGAGCACCAGGTGCCAGGACCAGGCGGCCACCACCACAGTCTCTACTCCACCCCACAGACGTGATCCCCCTCCCTC
CCCCACAGAATACCCAGGCCCCAGTCCCCCTCACCCTAGGCCCCTGTGCCAAGTTTGTCTGCCGCTTCTTGCCCAGGATCCTGGGGGTCG

>In-frame_USP32_ENST00000393003_chr17_58469243_-_GPR137_ENST00000411458_chr11_64053982_+_1327nt
ATGGGTGCCAAGGAGTCACGGATCGGATTCCTCAGCTACGAGGAGGCGCTGAGGAGAGGCCTCCCTCCCTGACATGGAGAGTAACCTGTC
TGGCCTGGTGCCTGCTGCCGGGCTGGTGCCTGCGCTGCCACCTGCTGTGACCCTGGGGCTGACAGCTGCCTACACCACCCTGTATGCCCT
GCTCTTCTTCTCCGTCTATGCCCAGCTCTGGCTGGTGCTTCTGTATGGGCACAAGCGTCTCAGCTATCAGACGGTGTTCCTGGCCCTCTG
TCTGCTCTGGGCCGCCTTGCGTACCACCCTCTTCTCCTTCTACTTCCGAGATACTCCCCGCGCCAACCGCCTGGGGCCCTTGCCCTTCTG
GCTTCTCTACTGCTGCCCCGTCTGCCTGCAGTTCTTCACCTTGACGCTTATGAACCTCTACTTTGCCCAGGTGGTGTTCAAGGCCAAGGT
GAAGCGTCGGCCGGAGATGAGCCGAGGCTTGCTCGCTGTCCGAGGGGCCTTTGTGGGGGCCTCGCTGCTCTTTCTGCTGGTGAACGTGCT
GTGTGCTGTGCTCTCCCATCGGCGCCGGGCACAGCCCTGGGCCCTGCTGCTTGTCCGCGTCCTGGTGAGCGACTCCCTGTTCGTCATCTG
CGCGCTGTCTCTTGCTGCCTGCCTCTGCCTCGTCGCCAGGCGGGCGCCCTCCACTAGCATCTACCTGGAGGCCAAGGGGACCAGTGTGTG
CCAGGCGGCCGCGATGGGTGGCGCCATGGTCCTGCTCTATGCCAGCCGGGCCTGCTACAACCTGACAGCACTGGCCTTGGCCCCCCAGAG
CCGGCTGGACACCTTCGATTACGACTGGTACAATGTGTCTGACCAGGCGGACCTGGTGAATGACCTGGGGAACAAAGGCTACCTGGTATT
TGGCCTCATCCTCTTCGTGTGGGAGCTACTGCCCACCACCCTGCTGGTGGGCTTCTTCCGGGTGCACCGGCCCCCACAGGACCTGAGCAC
CAGCCACATCCTCAATGGGCAGGTCTTTGCCTCTCGGTCCTACTTCTTTGACCGGGCTGGGCACTGTGAAGATGAGGGCTGCTCCTGGGA
GCACAGCCGGGGTGAGAGCACCAGGTGCCAGGACCAGGCGGCCACCACCACAGTCTCTACTCCACCCCACAGACGTGATCCCCCTCCCTC
CCCCACAGAATACCCAGGCCCCAGTCCCCCTCACCCTAGGCCCCTGTGCCAAGTTTGTCTGCCGCTTCTTGCCCAGGATCCTGGGGGTCG


* Fusion transcript sequences (Full-length transcript).
>In-frame_USP32_ENST00000300896_chr17_58469243_-_GPR137_ENST00000411458_chr11_64053982_+_1561nt
ACGTGATCCGGCATGGAGGCGGTGGCGGCGACCGGGAGGAGCCGCCGGGGCAGAAGCCGCACTTGTTAGTGTGGGGGGAGGTGGGGGCGG
GGGACGCCGACACCGTCACCGTCACCCAGGGACGCCGAGGAGAAGGCGGGAGGGGGGTGGGGGCGAGATCAGGCTCCGACCCCCCGCCGA
GGGGATGAGGGGAGCATGGGTGCCAAGGAGTCACGGATCGGATTCCTCAGCTACGAGGAGGCGCTGAGGAGAGGCCTCCCTCCCTGACAT
GGAGAGTAACCTGTCTGGCCTGGTGCCTGCTGCCGGGCTGGTGCCTGCGCTGCCACCTGCTGTGACCCTGGGGCTGACAGCTGCCTACAC
CACCCTGTATGCCCTGCTCTTCTTCTCCGTCTATGCCCAGCTCTGGCTGGTGCTTCTGTATGGGCACAAGCGTCTCAGCTATCAGACGGT
GTTCCTGGCCCTCTGTCTGCTCTGGGCCGCCTTGCGTACCACCCTCTTCTCCTTCTACTTCCGAGATACTCCCCGCGCCAACCGCCTGGG
GCCCTTGCCCTTCTGGCTTCTCTACTGCTGCCCCGTCTGCCTGCAGTTCTTCACCTTGACGCTTATGAACCTCTACTTTGCCCAGGTGGT
GTTCAAGGCCAAGGTGAAGCGTCGGCCGGAGATGAGCCGAGGCTTGCTCGCTGTCCGAGGGGCCTTTGTGGGGGCCTCGCTGCTCTTTCT
GCTGGTGAACGTGCTGTGTGCTGTGCTCTCCCATCGGCGCCGGGCACAGCCCTGGGCCCTGCTGCTTGTCCGCGTCCTGGTGAGCGACTC
CCTGTTCGTCATCTGCGCGCTGTCTCTTGCTGCCTGCCTCTGCCTCGTCGCCAGGCGGGCGCCCTCCACTAGCATCTACCTGGAGGCCAA
GGGGACCAGTGTGTGCCAGGCGGCCGCGATGGGTGGCGCCATGGTCCTGCTCTATGCCAGCCGGGCCTGCTACAACCTGACAGCACTGGC
CTTGGCCCCCCAGAGCCGGCTGGACACCTTCGATTACGACTGGTACAATGTGTCTGACCAGGCGGACCTGGTGAATGACCTGGGGAACAA
AGGCTACCTGGTATTTGGCCTCATCCTCTTCGTGTGGGAGCTACTGCCCACCACCCTGCTGGTGGGCTTCTTCCGGGTGCACCGGCCCCC
ACAGGACCTGAGCACCAGCCACATCCTCAATGGGCAGGTCTTTGCCTCTCGGTCCTACTTCTTTGACCGGGCTGGGCACTGTGAAGATGA
GGGCTGCTCCTGGGAGCACAGCCGGGGTGAGAGCACCAGGTGCCAGGACCAGGCGGCCACCACCACAGTCTCTACTCCACCCCACAGACG
TGATCCCCCTCCCTCCCCCACAGAATACCCAGGCCCCAGTCCCCCTCACCCTAGGCCCCTGTGCCAAGTTTGTCTGCCGCTTCTTGCCCA
GGATCCTGGGGGTCGTGGCTACCCCCTCCTCTGGCCGGCTCCTTGCTGCTCCTGTCATAGTGAGCTTGTGCCGTCCCCCTAGGATGGGGG

>In-frame_USP32_ENST00000393003_chr17_58469243_-_GPR137_ENST00000411458_chr11_64053982_+_1402nt
CAGGCTCCGACCCCCCGCCGAGGGGATGAGGGGAGCATGGGTGCCAAGGAGTCACGGATCGGATTCCTCAGCTACGAGGAGGCGCTGAGG
AGAGGCCTCCCTCCCTGACATGGAGAGTAACCTGTCTGGCCTGGTGCCTGCTGCCGGGCTGGTGCCTGCGCTGCCACCTGCTGTGACCCT
GGGGCTGACAGCTGCCTACACCACCCTGTATGCCCTGCTCTTCTTCTCCGTCTATGCCCAGCTCTGGCTGGTGCTTCTGTATGGGCACAA
GCGTCTCAGCTATCAGACGGTGTTCCTGGCCCTCTGTCTGCTCTGGGCCGCCTTGCGTACCACCCTCTTCTCCTTCTACTTCCGAGATAC
TCCCCGCGCCAACCGCCTGGGGCCCTTGCCCTTCTGGCTTCTCTACTGCTGCCCCGTCTGCCTGCAGTTCTTCACCTTGACGCTTATGAA
CCTCTACTTTGCCCAGGTGGTGTTCAAGGCCAAGGTGAAGCGTCGGCCGGAGATGAGCCGAGGCTTGCTCGCTGTCCGAGGGGCCTTTGT
GGGGGCCTCGCTGCTCTTTCTGCTGGTGAACGTGCTGTGTGCTGTGCTCTCCCATCGGCGCCGGGCACAGCCCTGGGCCCTGCTGCTTGT
CCGCGTCCTGGTGAGCGACTCCCTGTTCGTCATCTGCGCGCTGTCTCTTGCTGCCTGCCTCTGCCTCGTCGCCAGGCGGGCGCCCTCCAC
TAGCATCTACCTGGAGGCCAAGGGGACCAGTGTGTGCCAGGCGGCCGCGATGGGTGGCGCCATGGTCCTGCTCTATGCCAGCCGGGCCTG
CTACAACCTGACAGCACTGGCCTTGGCCCCCCAGAGCCGGCTGGACACCTTCGATTACGACTGGTACAATGTGTCTGACCAGGCGGACCT
GGTGAATGACCTGGGGAACAAAGGCTACCTGGTATTTGGCCTCATCCTCTTCGTGTGGGAGCTACTGCCCACCACCCTGCTGGTGGGCTT
CTTCCGGGTGCACCGGCCCCCACAGGACCTGAGCACCAGCCACATCCTCAATGGGCAGGTCTTTGCCTCTCGGTCCTACTTCTTTGACCG
GGCTGGGCACTGTGAAGATGAGGGCTGCTCCTGGGAGCACAGCCGGGGTGAGAGCACCAGGTGCCAGGACCAGGCGGCCACCACCACAGT
CTCTACTCCACCCCACAGACGTGATCCCCCTCCCTCCCCCACAGAATACCCAGGCCCCAGTCCCCCTCACCCTAGGCCCCTGTGCCAAGT
TTGTCTGCCGCTTCTTGCCCAGGATCCTGGGGGTCGTGGCTACCCCCTCCTCTGGCCGGCTCCTTGCTGCTCCTGTCATAGTGAGCTTGT


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FusionGenePPI for USP32_GPR137


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
USP32CDK1, FARSA, KRT8, KRT18, KRT19, ABCD3, YWHAB, TUBA1A, SMC1A, USP6, TRIP13, ERP44, UBXN1, MRPL39, VPS35, LRRC47, USP32P2, USP4, CUL3, CAND1, RBCK1, TRIM46, RNF144A, TRIM74, ZDHHC17, RAP1B, SORT1, SYNCRIP, BAG6, FDFT1, RAB6B, TPCN2, MANSC1, ENTPD7, ALDH3B1, CD83, NME4, HSPA12A, UBC, MTNR1A, TRIM25GPR137IPPK, LPAR1, DPEP1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for USP32_GPR137


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for USP32_GPR137


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource