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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 4079

FusionGeneSummary for BCOR_RARA

check button Fusion gene summary
Fusion gene informationFusion gene name: BCOR_RARA
Fusion gene ID: 4079
HgeneTgene
Gene symbol

BCOR

RARA

Gene ID

54880

5914

Gene nameBCL6 corepressorretinoic acid receptor alpha
SynonymsANOP2|MAA2|MCOPS2NR1B1|RAR
Cytomap

Xp11.4

17q21.2

Type of geneprotein-codingprotein-coding
DescriptionBCL-6 corepressorBCL-6 interacting corepressorretinoic acid receptor alphaRAR-alphanuclear receptor subfamily 1 group B member 1nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long formretinoic acid nuclear receptor alpha variant 1retinoic acid nuclear receptor alpha variant 2
Modification date2018052720180523
UniProtAcc

Q6W2J9

P10276

Ensembl transtripts involved in fusion geneENST00000378455, ENST00000342274, 
ENST00000378463, ENST00000397354, 
ENST00000378444, 
ENST00000254066, 
ENST00000394089, ENST00000425707, 
ENST00000394086, ENST00000394081, 
ENST00000420042, 
Fusion gene scores* DoF score7 X 7 X 3=14718 X 16 X 10=2880
# samples 842
** MAII scorelog2(8/147*10)=-0.877744249949002
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(42/2880*10)=-2.77760757866355
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: BCOR [Title/Abstract] AND RARA [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneBCOR

GO:0035518

histone H2A monoubiquitination

16943429

HgeneBCOR

GO:0045892

negative regulation of transcription, DNA-templated

10898795

TgeneRARA

GO:0007165

signal transduction

2825025

TgeneRARA

GO:0030853

negative regulation of granulocyte differentiation

19917671

TgeneRARA

GO:0032689

negative regulation of interferon-gamma production

18416830

TgeneRARA

GO:0032720

negative regulation of tumor necrosis factor production

18416830

TgeneRARA

GO:0032736

positive regulation of interleukin-13 production

18416830

TgeneRARA

GO:0032753

positive regulation of interleukin-4 production

18416830

TgeneRARA

GO:0032754

positive regulation of interleukin-5 production

18416830

TgeneRARA

GO:0045630

positive regulation of T-helper 2 cell differentiation

18416830

TgeneRARA

GO:0045892

negative regulation of transcription, DNA-templated

20080953

TgeneRARA

GO:0045893

positive regulation of transcription, DNA-templated

18845237|19850744|20080953

TgeneRARA

GO:0045944

positive regulation of transcription by RNA polymerase II

19850744

TgeneRARA

GO:0071300

cellular response to retinoic acid

19917671

TgeneRARA

GO:0071391

cellular response to estrogen stimulus

20080953


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1HM597846BCORchrX

39914621

-RARAchr17

38504566

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shitENST00000378455ENST00000254066BCORchrX

39914621

-RARAchr17

38504566

+
Frame-shitENST00000378455ENST00000394089BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000378455ENST00000425707BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000378455ENST00000394086BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000378455ENST00000394081BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000378455ENST00000420042BCORchrX

39914621

-RARAchr17

38504566

+
Frame-shitENST00000342274ENST00000254066BCORchrX

39914621

-RARAchr17

38504566

+
Frame-shitENST00000342274ENST00000394089BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000342274ENST00000425707BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000342274ENST00000394086BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000342274ENST00000394081BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000342274ENST00000420042BCORchrX

39914621

-RARAchr17

38504566

+
Frame-shitENST00000378463ENST00000254066BCORchrX

39914621

-RARAchr17

38504566

+
Frame-shitENST00000378463ENST00000394089BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000378463ENST00000425707BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000378463ENST00000394086BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000378463ENST00000394081BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000378463ENST00000420042BCORchrX

39914621

-RARAchr17

38504566

+
In-frameENST00000397354ENST00000254066BCORchrX

39914621

-RARAchr17

38504566

+
In-frameENST00000397354ENST00000394089BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000397354ENST00000425707BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000397354ENST00000394086BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000397354ENST00000394081BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000397354ENST00000420042BCORchrX

39914621

-RARAchr17

38504566

+
In-frameENST00000378444ENST00000254066BCORchrX

39914621

-RARAchr17

38504566

+
In-frameENST00000378444ENST00000394089BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000378444ENST00000425707BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000378444ENST00000394086BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000378444ENST00000394081BCORchrX

39914621

-RARAchr17

38504566

+
5CDS-intronENST00000378444ENST00000420042BCORchrX

39914621

-RARAchr17

38504566

+

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FusionProtFeatures for BCOR_RARA


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
BCOR

Q6W2J9

RARA

P10276

Receptor for retinoic acid. Retinoic acid receptors bindas heterodimers to their target response elements in response totheir ligands, all-trans or 9-cis retinoic acid, and regulate geneexpression in various biological processes. The RXR/RARheterodimers bind to the retinoic acid response elements (RARE)composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In theabsence of ligand, the RXR-RAR heterodimers associate with amultiprotein complex containing transcription corepressors thatinduce histone acetylation, chromatin condensation andtranscriptional suppression. On ligand binding, the corepressorsdissociate from the receptors and associate with the coactivatorsleading to transcriptional activation. RARA plays an essentialrole in the regulation of retinoic acid-induced germ celldevelopment during spermatogenesis. Has a role in the survival ofearly spermatocytes at the beginning prophase of meiosis. InSertoli cells, may promote the survival and development of earlymeiotic prophase spermatocytes. In concert with RARG, required forskeletal growth, matrix homeostasis and growth plate function (Bysimilarity). {ECO:0000250|UniProtKB:P11416,ECO:0000269|PubMed:16417524, ECO:0000269|PubMed:19850744,ECO:0000269|PubMed:20215566}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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FusionGeneSequence for BCOR_RARA


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).
>In-frame_BCOR_ENST00000397354_chrX_39914621_-_RARA_ENST00000254066_chr17_38504566_+_6649nt
GCTCGCCGCGCTTCTCCGGCCCGGCTCCTTCTCCGCTCGTTAACGTCGCCAACCCCCCCCACCCCTCATATCTCTCTCCACCCACCCAAC
CGCCCCCCGCTCCTTCTCGCCGCCTCGAGTCCGCTTGGGGGAAAACTTCAAAGAGCCGGATCGCAGGCTCCCTGCCTACTCCCCCACCGG
GGATTTCAGACTAGACGCTTGAAGCAAAGCTGCCATCCCAGAAGACGACATGCTCTCAGCAACCCCCCTGTATGGGAACGTTCACAGCTG
GATGAACAGCGAGAGGGTCCGCATGTGTGGGGCGAGCGAAGACAGGAAAATCCTTGTAAATGATGGTGACGCTTCAAAAGCCAGACTGGA
ACTGAGGGAAGAGAATCCCTTGAACCACAACGTGGTGGATGCGAGCACGGCCCATAGGATCGATGGCCTGGCAGCACTGAGCATGGACCG
CACTGGCCTGATCCGGGAAGGGCTGCGGGTCCCGGGAAACATCGTCTATTCTAGCTTGTGTGGACTGGGCTCAGAGAAAGGTCGGGAGGC
TGCCACAAGCACTCTAGGTGGCCTTGGGTTTTCTTCGGAAAGAAATCCAGAGATGCAGTTCAAACCGAATACACCCGAGACAGTGGAGGC
TTCTGCCGTCTCTGGAAAACCCCCAAATGGCTTCAGTGCTATATACAAAACACCGCCTGGAATACAAAAAAGTGCTGTAGCCACAGCAGA
AGCGCTGGGCTTGGACAGGCCTGCCAGCGACAAACAGAGCCCTCTCAACATCAATGGTGCTAGTTATCTGCGGCTGCCCTGGGTCAATCC
TTACATGGAGGGTGCCACGCCAGCCATCTACCCTTTCCTCGACTCGCCAAATAAGTATTCACTGAACATGTACAAGGCCTTGCTACCTCA
GCAGTCCTACAGCTTGGCCCAGCCGCTGTATTCTCCAGTCTGCACCAATGGGGAGCGCTTTCTCTACCTGCCGCCACCTCACTACGTCGG
TCCCCACATCCCATCGTCCTTGGCATCACCCATGAGGCTCTCGACACCTTCGGCCTCCCCAGCCATCCCGCCTCTCGTCCATTGCGCAGA
CAAAAGCCTCCCGTGGAAGATGGGCGTCAGCCCTGGGAATCCTGTTGATTCCCACGCCTATCCTCACATCCAGAACAGTAAGCAGCCCAG
GGTTCCCTCTGCCAAGGCGGTCACCAGTGGCCTGCCGGGGGACACAGCTCTCCTGTTGCCCCCCTCGCCTCGGCCGTCACCCCGAGTCCA
CCTTCCCACCCAGCCTGCTGCAGACACCTACTCGGAGTTCCACAAGCACTATGCCAGGATCTCCACCTCTCCTTCAGTTGCCCTGTCAAA
GCCATACATGACAGTTAGCAGCGAGTTCCCCGCGGCCAGGCTCTCCAATGGCAAGTATCCCAAGGCTCCGGAAGGGGGCGAAGGTGCCCA
GCCAGTGCCCGGGCATGCCCGGAAGACAGCGGTTCAAGACAGAAAAGATGGCAGCTCACCTCCTCTGTTGGAGAAGCAGACCGTTACCAA
AGACGTCACAGATAAGCCACTAGACTTGTCTTCTAAAGTGGTGGATGTAGATGCTTCCAAAGCTGACCACATGAAAAAGATGGCTCCCAC
GGTCCTGGTTCACAGCAGGGCTGGAAGTGGCTTAGTGCTCTCCGGAAGTGAGATTCCGAAAGAAACACTATCTCCTCCAGGAAATGGTTG
TGCTATCTATAGATCTGAAATCATCAGCACTGCTCCCTCATCCTGGGTGGTGCCCGGGCCAAGTCCTAACGAAGAGAACAATGGCAAAAG
CATGTCGCTGAAAAACAAGGCATTGGACTGGGCGATACCACAGCAGCGGAGTTCATCATGCCCGCGCATGGGCGGCACCGATGCTGTCAT
CACTAACGTTTCAGGGTCAGTGTCGAGTGCAGGCCGCCCAGCCTCCGCATCACCCGCCCCCAATGCCAATGCAGATGGCACCAAAACCAG
CAGGAGCTCTGTAGAAACCACACCATCCGTTATTCAGCACGTGGGCCAGCCCCCGGCCACTCCTGCCAAGCACAGTAGCAGCACCAGCAG
CAAGGGCGCCAAAGCCAGCAACCCAGAACCGAGTTTCAAAGCAAACGAGAACGGCCTTCCACCAAGCTCTATATTTCTGTCTCCAAATGA
GGCATTCAGGTCCCCACCAATTCCCTACCCCAGGAGTTACCTCCCTTACCCAGCCCCTGAGGGCATTGCTGTAAGTCCCCTCTCCTTACA
TGGCAAAGGACCTGTCTACCCTCACCCAGTTTTGTTACCCAATGGCAGTCTGTTTCCTGGGCACCTTGCCCCAAAGCCTGGGCTGCCCTA
TGGGCTTCCCACCGGCCGTCCAGAGTTTGTGACCTACCAAGATGCCCTGGGGTTGGGCATGGTGCATCCCATGTTGATACCACACACGCC
CATAGAGATTACTAAAGAGGAGAAACCAGAGAGGAGATCCCGGTCCCATGAGAGAGCCCGTTACGAGGACCCAACCCTCCGGAATCGGTT
TTCCGAGATTTTGGAAACTAGCAGCACCAAGTTACATCCAGATGTCCCCACCGACAAGAACCTAAAGCCGAACCCCAACTGGAATCAAGG
GAAGACTGTTGTCAAAAGCGACAAGCTTGTCTACGTAGACCTTCTCCGAGAAGAACCAGATGCTAAAACTGACACAAACGTGTCCAAACC
CAGCTTTGCAGCAGAGAGTGTTGGCCAGAGCGCTGAGCCCCCCAAGCCCTCAGTTGAGCCGGCCCTGCAGCAGCACCGTGATTTCATCGC
CCTGAGAGAGGAGTTGGGGCGCATCAGTGACTTCCACGAAACTTATACTTTCAAACAGCCAGTCTTCACCGTAAGCAAGGACAGTGTTCT
GGCAGGTACCAACAAAGAGAACCTAGGGTTGCCAGTCTCGACTCCATTCCTGGAGCCACCTCTGGGGAGCGATGGCCCTGCTGTAACTTT
TGGTAAAACCCAAGAGGATCCCAAACCATTTTGTGTGGGCAGTGCCCCACCAAGTGTGGATGTGACCCCCACCTATACCAAAGATGGAGC
TGATGAGGCTGAATCAAATGATGGCAAAGTTCTGAAACCGAAGCCATCTAAGCTGGCAAAGAGAATCGCCAACTCAGCGGGTTACGTGGG
TGACCGATTCAAATGTGTCACTACCGAACTGTATGCAGATTCCAGTCAGCTCAGCCGGGAGCAACGGGCATTGCAGATGGAAGGATTACA
AGAGGACAGTATTTTATGTCTACCCGCTGCTTACTGTGAGCGTGCAATGATGCGCTTCTCAGAGTTGGAGATGAAAGAAAGAGAAGGTGG
CCACCCAGCAACCAAAGACTCCGAGATGTGCAAATTCAGCCCAGCCGACTGGGAAAGGTTGAAAGGAAATCAGGACAAAAAGCCAAAGTC
GGTCACCCTGGAGGAGGCCATTGCAGAACAGAACGAAAGTGAGAGATGCGAGTATAGTGTTGGAAACAAGCACCGTGATCCCTTTGAAGC
CCCAGAGGACAAAGATCTTCCTGTGGAGAAGTACTTTGTGGAGAGGCAGCCTGTGAGCGAGCCTCCCGCAGACCAGGTGGCCTCGGACAT
GCCTCACAGCCCCACCCTCCGGGTGGACAGGAAACGCAAAGTCTCAGGTGACAGCAGCCACACTGAGACCACTGCGGAGGAGGTGCCAGA
GGACCCTCTGCTGAAAGCCAAACGCCGACGAGTCTCTAAAGGGCTCCATCCTAAAAAACAACGCCACTTGCTGCACCTTAGAGAACGATG
GGAGCAGCAGGTGTCGGCAGCAGATGGCAAACCTGGCCGGCAAAGCAGGAAGGAAGTGACCCAGGCCACTCAGCCTGAGGCCATTCCTCA
GGGGACTAACATCACTGAAGAGAAACCTGGCAGGAAAAGGGCAGAGGCCAAAGGCAACAGAAGCTGGTCGGAAGAGTCTCTTAAACCCAG
TGACAATGAACAAGGCTTGCCTGTGTTCTCCGGCTCTCCGCCCATGAAGAGTCTTTCATCCACCAGTGCAGGCGGCAAAAAGCAGGCTCA
GCCAAGCTGCGCACCAGCCTCCAGGCCGCCTGCCAAACAGCAGAAAATTAAAGAAAACCAGAAGACAGATGTGCTGTGTGCAGACGAAGA
AGAGGATTGCCAGGCTGCCTCCCTGCTGCAGAAATACACCGACAACAGCGAGAAGCCATCCGGGAAGAGACTGTGCAAAACCAAACACTT
GATCCCTCAGGAGTCCAGGCGGGGATTGCCACTGACAGGGGAATACTACGTGGAGAATGCCGATGGCAAGGTGACTGTCCGGAGATTCAG
AAAGCGGCCGGAGCCCAGTTCGGACTATGATCTGTCACCAGCCAAGCAGGAGCCAAAGCCCTTCGACCGCTTGCAGCAACTGCTACCAGC
CTCCCAGTCCACACAGCTGCCATGCTCAAGTTCCCCTCAGGAGACCACCCAGTCTCGCCCTATGCCGCCGGAAGCACGGAGACTTATTGT
CAATAAGAACGCTGGCGAGACCCTTCTGCAGCGGGCAGCCAGGCTTGGCTATGAGGAAGTGGTCCTGTACTGCTTAGAGAACAAGATTTG
TGATGTAAATCATCGGGACAACGCAGGTTACTGCGCCCTGCATGAAGCTTGTGCTAGGGGCTGGCTCAACATTGTGCGACACCTCCTTGA
ATATGGCGCTGATGTCAACTGTAGTGCCCAGGATGGAACCAGGCCTCTGCACGATGCTGTTGAGAACGATCACTTGGAAATTGTCCGACT
ACTTCTCTCTTATGGTGCTGACCCCACCTTGGCTACGTACTCAGGTAGAACCATCATGAAAATGACCCACAGTGAACTTATGGAAAAGTT
CTTAACAGCCATTGAGACCCAGAGCAGCAGTTCTGAAGAGATAGTGCCCAGCCCTCCCTCGCCACCCCCTCTACCCCGCATCTACAAGCC
TTGCTTTGTCTGTCAGGACAAGTCCTCAGGCTACCACTATGGGGTCAGCGCCTGTGAGGGCTGCAAGGGCTTCTTCCGCCGCAGCATCCA
GAAGAACATGGTGTACACGTGTCACCGGGACAAGAACTGCATCATCAACAAGGTGACCCGGAACCGCTGCCAGTACTGCCGACTGCAGAA
GTGCTTTGAAGTGGGCATGTCCAAGGAGTCTGTGAGAAACGACCGAAACAAGAAGAAGAAGGAGGTGCCCAAGCCCGAGTGCTCTGAGAG
CTACACGCTGACGCCGGAGGTGGGGGAGCTCATTGAGAAGGTGCGCAAAGCGCACCAGGAAACCTTCCCTGCCCTCTGCCAGCTGGGCAA
ATACACTACGAACAACAGCTCAGAACAACGTGTCTCTCTGGACATTGACCTCTGGGACAAGTTCAGTGAACTCTCCACCAAGTGCATCAT
TAAGACTGTGGAGTTCGCCAAGCAGCTGCCCGGCTTCACCACCCTCACCATCGCCGACCAGATCACCCTCCTCAAGGCTGCCTGCCTGGA
CATCCTGATCCTGCGGATCTGCACGCGGTACACGCCCGAGCAGGACACCATGACCTTCTCGGACGGGCTGACCCTGAACCGGACCCAGAT
GCACAACGCTGGCTTCGGCCCCCTCACCGACCTGGTCTTTGCCTTCGCCAACCAGCTGCTGCCCCTGGAGATGGATGATGCGGAGACGGG
GCTGCTCAGCGCCATCTGCCTCATCTGCGGAGACCGCCAGGACCTGGAGCAGCCGGACCGGGTGGACATGCTGCAGGAGCCGCTGCTGGA
GGCGCTAAAGGTCTACGTGCGGAAGCGGAGGCCCAGCCGCCCCCACATGTTCCCCAAGATGCTAATGAAGATTACTGACCTGCGAAGCAT
CAGCGCCAAGGGGGCTGAGCGGGTGATCACGCTGAAGATGGAGATCCCGGGCTCCATGCCGCCTCTCATCCAGGAAATGTTGGAGAACTC
AGAGGGCCTGGACACTCTGAGCGGACAGCCGGGGGGTGGGGGGCGGGACGGGGGTGGCCTGGCCCCCCCGCCAGGCAGCTGTAGCCCCAG
CCTCAGCCCCAGCTCCAACAGAAGCAGCCCGGCCACCCACTCCCCGTGACCGCCCACGCCACATGGACACAGCCCTCGCCCTCCGCCCCG
GCTTTTCTCTGCCTTTCTACCGACCATGTGACCCCGCACCAGCCCTGCCCCCACCTGCCCTCCCGGGCAGTACTGGGGACCTTCCCTGGG
GGACGGGGAGGGAGGAGGCAGCGACTCCTTGGACAGAGGCCTGGGCCCTCAGTGGACTGCCTGCTCCCACAGCCTGGGCTGACGTCAGAG
GCCGAGGCCAGGAACTGAGTGAGGCCCCTGGTCCTGGGTCTCAGGATGGGTCCTGGGGGCCTCGTGTTCATCAAGACACCCCTCTGCCCA
GCTCACCACATCTTCATCACCAGCAAACGCCAGGACTTGGCTCCCCCATCCTCAGAACTCACAAGCCATTGCTCCCCAGCTGGGGAACCT
CAACCTCCCCCCTGCCTCGGTTGGTGACAGAGGGGGTGGGACAGGGGCGGGGGGTTCCCCCTGTACATACCCTGCCATACCAACCCCAGG

>In-frame_BCOR_ENST00000397354_chrX_39914621_-_RARA_ENST00000394089_chr17_38504566_+_6184nt
GCTCGCCGCGCTTCTCCGGCCCGGCTCCTTCTCCGCTCGTTAACGTCGCCAACCCCCCCCACCCCTCATATCTCTCTCCACCCACCCAAC
CGCCCCCCGCTCCTTCTCGCCGCCTCGAGTCCGCTTGGGGGAAAACTTCAAAGAGCCGGATCGCAGGCTCCCTGCCTACTCCCCCACCGG
GGATTTCAGACTAGACGCTTGAAGCAAAGCTGCCATCCCAGAAGACGACATGCTCTCAGCAACCCCCCTGTATGGGAACGTTCACAGCTG
GATGAACAGCGAGAGGGTCCGCATGTGTGGGGCGAGCGAAGACAGGAAAATCCTTGTAAATGATGGTGACGCTTCAAAAGCCAGACTGGA
ACTGAGGGAAGAGAATCCCTTGAACCACAACGTGGTGGATGCGAGCACGGCCCATAGGATCGATGGCCTGGCAGCACTGAGCATGGACCG
CACTGGCCTGATCCGGGAAGGGCTGCGGGTCCCGGGAAACATCGTCTATTCTAGCTTGTGTGGACTGGGCTCAGAGAAAGGTCGGGAGGC
TGCCACAAGCACTCTAGGTGGCCTTGGGTTTTCTTCGGAAAGAAATCCAGAGATGCAGTTCAAACCGAATACACCCGAGACAGTGGAGGC
TTCTGCCGTCTCTGGAAAACCCCCAAATGGCTTCAGTGCTATATACAAAACACCGCCTGGAATACAAAAAAGTGCTGTAGCCACAGCAGA
AGCGCTGGGCTTGGACAGGCCTGCCAGCGACAAACAGAGCCCTCTCAACATCAATGGTGCTAGTTATCTGCGGCTGCCCTGGGTCAATCC
TTACATGGAGGGTGCCACGCCAGCCATCTACCCTTTCCTCGACTCGCCAAATAAGTATTCACTGAACATGTACAAGGCCTTGCTACCTCA
GCAGTCCTACAGCTTGGCCCAGCCGCTGTATTCTCCAGTCTGCACCAATGGGGAGCGCTTTCTCTACCTGCCGCCACCTCACTACGTCGG
TCCCCACATCCCATCGTCCTTGGCATCACCCATGAGGCTCTCGACACCTTCGGCCTCCCCAGCCATCCCGCCTCTCGTCCATTGCGCAGA
CAAAAGCCTCCCGTGGAAGATGGGCGTCAGCCCTGGGAATCCTGTTGATTCCCACGCCTATCCTCACATCCAGAACAGTAAGCAGCCCAG
GGTTCCCTCTGCCAAGGCGGTCACCAGTGGCCTGCCGGGGGACACAGCTCTCCTGTTGCCCCCCTCGCCTCGGCCGTCACCCCGAGTCCA
CCTTCCCACCCAGCCTGCTGCAGACACCTACTCGGAGTTCCACAAGCACTATGCCAGGATCTCCACCTCTCCTTCAGTTGCCCTGTCAAA
GCCATACATGACAGTTAGCAGCGAGTTCCCCGCGGCCAGGCTCTCCAATGGCAAGTATCCCAAGGCTCCGGAAGGGGGCGAAGGTGCCCA
GCCAGTGCCCGGGCATGCCCGGAAGACAGCGGTTCAAGACAGAAAAGATGGCAGCTCACCTCCTCTGTTGGAGAAGCAGACCGTTACCAA
AGACGTCACAGATAAGCCACTAGACTTGTCTTCTAAAGTGGTGGATGTAGATGCTTCCAAAGCTGACCACATGAAAAAGATGGCTCCCAC
GGTCCTGGTTCACAGCAGGGCTGGAAGTGGCTTAGTGCTCTCCGGAAGTGAGATTCCGAAAGAAACACTATCTCCTCCAGGAAATGGTTG
TGCTATCTATAGATCTGAAATCATCAGCACTGCTCCCTCATCCTGGGTGGTGCCCGGGCCAAGTCCTAACGAAGAGAACAATGGCAAAAG
CATGTCGCTGAAAAACAAGGCATTGGACTGGGCGATACCACAGCAGCGGAGTTCATCATGCCCGCGCATGGGCGGCACCGATGCTGTCAT
CACTAACGTTTCAGGGTCAGTGTCGAGTGCAGGCCGCCCAGCCTCCGCATCACCCGCCCCCAATGCCAATGCAGATGGCACCAAAACCAG
CAGGAGCTCTGTAGAAACCACACCATCCGTTATTCAGCACGTGGGCCAGCCCCCGGCCACTCCTGCCAAGCACAGTAGCAGCACCAGCAG
CAAGGGCGCCAAAGCCAGCAACCCAGAACCGAGTTTCAAAGCAAACGAGAACGGCCTTCCACCAAGCTCTATATTTCTGTCTCCAAATGA
GGCATTCAGGTCCCCACCAATTCCCTACCCCAGGAGTTACCTCCCTTACCCAGCCCCTGAGGGCATTGCTGTAAGTCCCCTCTCCTTACA
TGGCAAAGGACCTGTCTACCCTCACCCAGTTTTGTTACCCAATGGCAGTCTGTTTCCTGGGCACCTTGCCCCAAAGCCTGGGCTGCCCTA
TGGGCTTCCCACCGGCCGTCCAGAGTTTGTGACCTACCAAGATGCCCTGGGGTTGGGCATGGTGCATCCCATGTTGATACCACACACGCC
CATAGAGATTACTAAAGAGGAGAAACCAGAGAGGAGATCCCGGTCCCATGAGAGAGCCCGTTACGAGGACCCAACCCTCCGGAATCGGTT
TTCCGAGATTTTGGAAACTAGCAGCACCAAGTTACATCCAGATGTCCCCACCGACAAGAACCTAAAGCCGAACCCCAACTGGAATCAAGG
GAAGACTGTTGTCAAAAGCGACAAGCTTGTCTACGTAGACCTTCTCCGAGAAGAACCAGATGCTAAAACTGACACAAACGTGTCCAAACC
CAGCTTTGCAGCAGAGAGTGTTGGCCAGAGCGCTGAGCCCCCCAAGCCCTCAGTTGAGCCGGCCCTGCAGCAGCACCGTGATTTCATCGC
CCTGAGAGAGGAGTTGGGGCGCATCAGTGACTTCCACGAAACTTATACTTTCAAACAGCCAGTCTTCACCGTAAGCAAGGACAGTGTTCT
GGCAGGTACCAACAAAGAGAACCTAGGGTTGCCAGTCTCGACTCCATTCCTGGAGCCACCTCTGGGGAGCGATGGCCCTGCTGTAACTTT
TGGTAAAACCCAAGAGGATCCCAAACCATTTTGTGTGGGCAGTGCCCCACCAAGTGTGGATGTGACCCCCACCTATACCAAAGATGGAGC
TGATGAGGCTGAATCAAATGATGGCAAAGTTCTGAAACCGAAGCCATCTAAGCTGGCAAAGAGAATCGCCAACTCAGCGGGTTACGTGGG
TGACCGATTCAAATGTGTCACTACCGAACTGTATGCAGATTCCAGTCAGCTCAGCCGGGAGCAACGGGCATTGCAGATGGAAGGATTACA
AGAGGACAGTATTTTATGTCTACCCGCTGCTTACTGTGAGCGTGCAATGATGCGCTTCTCAGAGTTGGAGATGAAAGAAAGAGAAGGTGG
CCACCCAGCAACCAAAGACTCCGAGATGTGCAAATTCAGCCCAGCCGACTGGGAAAGGTTGAAAGGAAATCAGGACAAAAAGCCAAAGTC
GGTCACCCTGGAGGAGGCCATTGCAGAACAGAACGAAAGTGAGAGATGCGAGTATAGTGTTGGAAACAAGCACCGTGATCCCTTTGAAGC
CCCAGAGGACAAAGATCTTCCTGTGGAGAAGTACTTTGTGGAGAGGCAGCCTGTGAGCGAGCCTCCCGCAGACCAGGTGGCCTCGGACAT
GCCTCACAGCCCCACCCTCCGGGTGGACAGGAAACGCAAAGTCTCAGGTGACAGCAGCCACACTGAGACCACTGCGGAGGAGGTGCCAGA
GGACCCTCTGCTGAAAGCCAAACGCCGACGAGTCTCTAAAGGGCTCCATCCTAAAAAACAACGCCACTTGCTGCACCTTAGAGAACGATG
GGAGCAGCAGGTGTCGGCAGCAGATGGCAAACCTGGCCGGCAAAGCAGGAAGGAAGTGACCCAGGCCACTCAGCCTGAGGCCATTCCTCA
GGGGACTAACATCACTGAAGAGAAACCTGGCAGGAAAAGGGCAGAGGCCAAAGGCAACAGAAGCTGGTCGGAAGAGTCTCTTAAACCCAG
TGACAATGAACAAGGCTTGCCTGTGTTCTCCGGCTCTCCGCCCATGAAGAGTCTTTCATCCACCAGTGCAGGCGGCAAAAAGCAGGCTCA
GCCAAGCTGCGCACCAGCCTCCAGGCCGCCTGCCAAACAGCAGAAAATTAAAGAAAACCAGAAGACAGATGTGCTGTGTGCAGACGAAGA
AGAGGATTGCCAGGCTGCCTCCCTGCTGCAGAAATACACCGACAACAGCGAGAAGCCATCCGGGAAGAGACTGTGCAAAACCAAACACTT
GATCCCTCAGGAGTCCAGGCGGGGATTGCCACTGACAGGGGAATACTACGTGGAGAATGCCGATGGCAAGGTGACTGTCCGGAGATTCAG
AAAGCGGCCGGAGCCCAGTTCGGACTATGATCTGTCACCAGCCAAGCAGGAGCCAAAGCCCTTCGACCGCTTGCAGCAACTGCTACCAGC
CTCCCAGTCCACACAGCTGCCATGCTCAAGTTCCCCTCAGGAGACCACCCAGTCTCGCCCTATGCCGCCGGAAGCACGGAGACTTATTGT
CAATAAGAACGCTGGCGAGACCCTTCTGCAGCGGGCAGCCAGGCTTGGCTATGAGGAAGTGGTCCTGTACTGCTTAGAGAACAAGATTTG
TGATGTAAATCATCGGGACAACGCAGGTTACTGCGCCCTGCATGAAGCTTGTGCTAGGGGCTGGCTCAACATTGTGCGACACCTCCTTGA
ATATGGCGCTGATGTCAACTGTAGTGCCCAGGATGGAACCAGGCCTCTGCACGATGCTGTTGAGAACGATCACTTGGAAATTGTCCGACT
ACTTCTCTCTTATGGTGCTGACCCCACCTTGGCTACGTACTCAGGTAGAACCATCATGAAAATGACCCACAGTGAACTTATGGAAAAGTT
CTTAACAGCCATTGAGACCCAGAGCAGCAGTTCTGAAGAGATAGTGCCCAGCCCTCCCTCGCCACCCCCTCTACCCCGCATCTACAAGCC
TTGCTTTGTCTGTCAGGACAAGTCCTCAGGCTACCACTATGGGGTCAGCGCCTGTGAGGGCTGCAAGGGCTTCTTCCGCCGCAGCATCCA
GAAGAACATGGTGTACACGTGTCACCGGGACAAGAACTGCATCATCAACAAGGTGACCCGGAACCGCTGCCAGTACTGCCGACTGCAGAA
GTGCTTTGAAGTGGGCATGTCCAAGGAGTCTGTGAGAAACGACCGAAACAAGAAGAAGAAGGAGGTGCCCAAGCCCGAGTGCTCTGAGAG
CTACACGCTGACGCCGGAGGTGGGGGAGCTCATTGAGAAGGTGCGCAAAGCGCACCAGGAAACCTTCCCTGCCCTCTGCCAGCTGGGCAA
ATACACTACGAACAACAGCTCAGAACAACGTGTCTCTCTGGACATTGACCTCTGGGACAAGTTCAGTGAACTCTCCACCAAGTGCATCAT
TAAGACTGTGGAGTTCGCCAAGCAGCTGCCCGGCTTCACCACCCTCACCATCGCCGACCAGATCACCCTCCTCAAGGCTGCCTGCCTGGA
CATCCTGATCCTGCGGATCTGCACGCGGTACACGCCCGAGCAGGACACCATGACCTTCTCGGACGGGCTGACCCTGAACCGGACCCAGAT
GCACAACGCTGGCTTCGGCCCCCTCACCGACCTGGTCTTTGCCTTCGCCAACCAGCTGCTGCCCCTGGAGATGGATGATGCGGAGACGGG
GCTGCTCAGCGCCATCTGCCTCATCTGCGGAGACCGCCAGGACCTGGAGCAGCCGGACCGGGTGGACATGCTGCAGGAGCCGCTGCTGGA
GGCGCTAAAGGTCTACGTGCGGAAGCGGAGGCCCAGCCGCCCCCACATGTTCCCCAAGATGCTAATGAAGATTACTGACCTGCGAAGCAT
CAGCGCCAAGGGGGCTGAGCGGGTGATCACGCTGAAGATGGAGATCCCGGGCTCCATGCCGCCTCTCATCCAGGAAATGTTGGAGAACTC
AGAGGGCCTGGACACTCTGAGCGGACAGCCGGGGGGTGGGGGGCGGGACGGGGGTGGCCTGGCCCCCCCGCCAGGCAGCTGTAGCCCCAG
CCTCAGCCCCAGCTCCAACAGAAGCAGCCCGGCCACCCACTCCCCGTGACCGCCCACGCCACATGGACACAGCCCTCGCCCTCCGCCCCG

>In-frame_BCOR_ENST00000378444_chrX_39914621_-_RARA_ENST00000254066_chr17_38504566_+_6751nt
GCTCGCCGCGCTTCTCCGGCCCGGCTCCTTCTCCGCTCGTTAACGTCGCCAACCCCCCCCACCCCTCATATCTCTCTCCACCCACCCAAC
CGCCCCCCGCTCCTTCTCGCCGCCTCGAGTCCGCTTGGGGGAAAACTTCAAAGAGCCGGATCGCAGGCTCCCTGCCTACTCCCCCACCGG
GGATTTCAGACTAGACGCTTGAAGCAAAGCTGCCATCCCAGAAGACGACATGCTCTCAGCAACCCCCCTGTATGGGAACGTTCACAGCTG
GATGAACAGCGAGAGGGTCCGCATGTGTGGGGCGAGCGAAGACAGGAAAATCCTTGTAAATGATGGTGACGCTTCAAAAGCCAGACTGGA
ACTGAGGGAAGAGAATCCCTTGAACCACAACGTGGTGGATGCGAGCACGGCCCATAGGATCGATGGCCTGGCAGCACTGAGCATGGACCG
CACTGGCCTGATCCGGGAAGGGCTGCGGGTCCCGGGAAACATCGTCTATTCTAGCTTGTGTGGACTGGGCTCAGAGAAAGGTCGGGAGGC
TGCCACAAGCACTCTAGGTGGCCTTGGGTTTTCTTCGGAAAGAAATCCAGAGATGCAGTTCAAACCGAATACACCCGAGACAGTGGAGGC
TTCTGCCGTCTCTGGAAAACCCCCAAATGGCTTCAGTGCTATATACAAAACACCGCCTGGAATACAAAAAAGTGCTGTAGCCACAGCAGA
AGCGCTGGGCTTGGACAGGCCTGCCAGCGACAAACAGAGCCCTCTCAACATCAATGGTGCTAGTTATCTGCGGCTGCCCTGGGTCAATCC
TTACATGGAGGGTGCCACGCCAGCCATCTACCCTTTCCTCGACTCGCCAAATAAGTATTCACTGAACATGTACAAGGCCTTGCTACCTCA
GCAGTCCTACAGCTTGGCCCAGCCGCTGTATTCTCCAGTCTGCACCAATGGGGAGCGCTTTCTCTACCTGCCGCCACCTCACTACGTCGG
TCCCCACATCCCATCGTCCTTGGCATCACCCATGAGGCTCTCGACACCTTCGGCCTCCCCAGCCATCCCGCCTCTCGTCCATTGCGCAGA
CAAAAGCCTCCCGTGGAAGATGGGCGTCAGCCCTGGGAATCCTGTTGATTCCCACGCCTATCCTCACATCCAGAACAGTAAGCAGCCCAG
GGTTCCCTCTGCCAAGGCGGTCACCAGTGGCCTGCCGGGGGACACAGCTCTCCTGTTGCCCCCCTCGCCTCGGCCGTCACCCCGAGTCCA
CCTTCCCACCCAGCCTGCTGCAGACACCTACTCGGAGTTCCACAAGCACTATGCCAGGATCTCCACCTCTCCTTCAGTTGCCCTGTCAAA
GCCATACATGACAGTTAGCAGCGAGTTCCCCGCGGCCAGGCTCTCCAATGGCAAGTATCCCAAGGCTCCGGAAGGGGGCGAAGGTGCCCA
GCCAGTGCCCGGGCATGCCCGGAAGACAGCGGTTCAAGACAGAAAAGATGGCAGCTCACCTCCTCTGTTGGAGAAGCAGACCGTTACCAA
AGACGTCACAGATAAGCCACTAGACTTGTCTTCTAAAGTGGTGGATGTAGATGCTTCCAAAGCTGACCACATGAAAAAGATGGCTCCCAC
GGTCCTGGTTCACAGCAGGGCTGGAAGTGGCTTAGTGCTCTCCGGAAGTGAGATTCCGAAAGAAACACTATCTCCTCCAGGAAATGGTTG
TGCTATCTATAGATCTGAAATCATCAGCACTGCTCCCTCATCCTGGGTGGTGCCCGGGCCAAGTCCTAACGAAGAGAACAATGGCAAAAG
CATGTCGCTGAAAAACAAGGCATTGGACTGGGCGATACCACAGCAGCGGAGTTCATCATGCCCGCGCATGGGCGGCACCGATGCTGTCAT
CACTAACGTTTCAGGGTCAGTGTCGAGTGCAGGCCGCCCAGCCTCCGCATCACCCGCCCCCAATGCCAATGCAGATGGCACCAAAACCAG
CAGGAGCTCTGTAGAAACCACACCATCCGTTATTCAGCACGTGGGCCAGCCCCCGGCCACTCCTGCCAAGCACAGTAGCAGCACCAGCAG
CAAGGGCGCCAAAGCCAGCAACCCAGAACCGAGTTTCAAAGCAAACGAGAACGGCCTTCCACCAAGCTCTATATTTCTGTCTCCAAATGA
GGCATTCAGGTCCCCACCAATTCCCTACCCCAGGAGTTACCTCCCTTACCCAGCCCCTGAGGGCATTGCTGTAAGTCCCCTCTCCTTACA
TGGCAAAGGACCTGTCTACCCTCACCCAGTTTTGTTACCCAATGGCAGTCTGTTTCCTGGGCACCTTGCCCCAAAGCCTGGGCTGCCCTA
TGGGCTTCCCACCGGCCGTCCAGAGTTTGTGACCTACCAAGATGCCCTGGGGTTGGGCATGGTGCATCCCATGTTGATACCACACACGCC
CATAGAGATTACTAAAGAGGAGAAACCAGAGAGGAGATCCCGGTCCCATGAGAGAGCCCGTTACGAGGACCCAACCCTCCGGAATCGGTT
TTCCGAGATTTTGGAAACTAGCAGCACCAAGTTACATCCAGATGTCCCCACCGACAAGAACCTAAAGCCGAACCCCAACTGGAATCAAGG
GAAGACTGTTGTCAAAAGCGACAAGCTTGTCTACGTAGACCTTCTCCGAGAAGAACCAGATGCTAAAACTGACACAAACGTGTCCAAACC
CAGCTTTGCAGCAGAGAGTGTTGGCCAGAGCGCTGAGCCCCCCAAGCCCTCAGTTGAGCCGGCCCTGCAGCAGCACCGTGATTTCATCGC
CCTGAGAGAGGAGTTGGGGCGCATCAGTGACTTCCACGAAACTTATACTTTCAAACAGCCAGTCTTCACCGTAAGCAAGGACAGTGTTCT
GGCAGGTACCAACAAAGAGAACCTAGGGTTGCCAGTCTCGACTCCATTCCTGGAGCCACCTCTGGGGAGCGATGGCCCTGCTGTAACTTT
TGGTAAAACCCAAGAGGATCCCAAACCATTTTGTGTGGGCAGTGCCCCACCAAGTGTGGATGTGACCCCCACCTATACCAAAGATGGAGC
TGATGAGGCTGAATCAAATGATGGCAAAGTTCTGAAACCGAAGCCATCTAAGCTGGCAAAGAGAATCGCCAACTCAGCGGGTTACGTGGG
TGACCGATTCAAATGTGTCACTACCGAACTGTATGCAGATTCCAGTCAGCTCAGCCGGGAGCAACGGGCATTGCAGATGGAAGGATTACA
AGAGGACAGTATTTTATGTCTACCCGCTGCTTACTGTGAGCGTGCAATGATGCGCTTCTCAGAGTTGGAGATGAAAGAAAGAGAAGGTGG
CCACCCAGCAACCAAAGACTCCGAGATGTGCAAATTCAGCCCAGCCGACTGGGAAAGGTTGAAAGGAAATCAGGACAAAAAGCCAAAGTC
GGTCACCCTGGAGGAGGCCATTGCAGAACAGAACGAAAGTGAGAGATGCGAGTATAGTGTTGGAAACAAGCACCGTGATCCCTTTGAAGC
CCCAGAGGACAAAGATCTTCCTGTGGAGAAGTACTTTGTGGAGAGGCAGCCTGTGAGCGAGCCTCCCGCAGACCAGGTGGCCTCGGACAT
GCCTCACAGCCCCACCCTCCGGGTGGACAGGAAACGCAAAGTCTCAGGTGACAGCAGCCACACTGAGACCACTGCGGAGGAGGTGCCAGA
GGACCCTCTGCTGAAAGCCAAACGCCGACGAGTCTCTAAAGATGACTGGCCTGAGAGGGAAATGACAAACAGTTCCTCTAACCACTTAGA
AGACCCACATTATAGTGAGCTGACCAACCTGAAGGTGTGCATTGAATTAACAGGGCTCCATCCTAAAAAACAACGCCACTTGCTGCACCT
TAGAGAACGATGGGAGCAGCAGGTGTCGGCAGCAGATGGCAAACCTGGCCGGCAAAGCAGGAAGGAAGTGACCCAGGCCACTCAGCCTGA
GGCCATTCCTCAGGGGACTAACATCACTGAAGAGAAACCTGGCAGGAAAAGGGCAGAGGCCAAAGGCAACAGAAGCTGGTCGGAAGAGTC
TCTTAAACCCAGTGACAATGAACAAGGCTTGCCTGTGTTCTCCGGCTCTCCGCCCATGAAGAGTCTTTCATCCACCAGTGCAGGCGGCAA
AAAGCAGGCTCAGCCAAGCTGCGCACCAGCCTCCAGGCCGCCTGCCAAACAGCAGAAAATTAAAGAAAACCAGAAGACAGATGTGCTGTG
TGCAGACGAAGAAGAGGATTGCCAGGCTGCCTCCCTGCTGCAGAAATACACCGACAACAGCGAGAAGCCATCCGGGAAGAGACTGTGCAA
AACCAAACACTTGATCCCTCAGGAGTCCAGGCGGGGATTGCCACTGACAGGGGAATACTACGTGGAGAATGCCGATGGCAAGGTGACTGT
CCGGAGATTCAGAAAGCGGCCGGAGCCCAGTTCGGACTATGATCTGTCACCAGCCAAGCAGGAGCCAAAGCCCTTCGACCGCTTGCAGCA
ACTGCTACCAGCCTCCCAGTCCACACAGCTGCCATGCTCAAGTTCCCCTCAGGAGACCACCCAGTCTCGCCCTATGCCGCCGGAAGCACG
GAGACTTATTGTCAATAAGAACGCTGGCGAGACCCTTCTGCAGCGGGCAGCCAGGCTTGGCTATGAGGAAGTGGTCCTGTACTGCTTAGA
GAACAAGATTTGTGATGTAAATCATCGGGACAACGCAGGTTACTGCGCCCTGCATGAAGCTTGTGCTAGGGGCTGGCTCAACATTGTGCG
ACACCTCCTTGAATATGGCGCTGATGTCAACTGTAGTGCCCAGGATGGAACCAGGCCTCTGCACGATGCTGTTGAGAACGATCACTTGGA
AATTGTCCGACTACTTCTCTCTTATGGTGCTGACCCCACCTTGGCTACGTACTCAGGTAGAACCATCATGAAAATGACCCACAGTGAACT
TATGGAAAAGTTCTTAACAGCCATTGAGACCCAGAGCAGCAGTTCTGAAGAGATAGTGCCCAGCCCTCCCTCGCCACCCCCTCTACCCCG
CATCTACAAGCCTTGCTTTGTCTGTCAGGACAAGTCCTCAGGCTACCACTATGGGGTCAGCGCCTGTGAGGGCTGCAAGGGCTTCTTCCG
CCGCAGCATCCAGAAGAACATGGTGTACACGTGTCACCGGGACAAGAACTGCATCATCAACAAGGTGACCCGGAACCGCTGCCAGTACTG
CCGACTGCAGAAGTGCTTTGAAGTGGGCATGTCCAAGGAGTCTGTGAGAAACGACCGAAACAAGAAGAAGAAGGAGGTGCCCAAGCCCGA
GTGCTCTGAGAGCTACACGCTGACGCCGGAGGTGGGGGAGCTCATTGAGAAGGTGCGCAAAGCGCACCAGGAAACCTTCCCTGCCCTCTG
CCAGCTGGGCAAATACACTACGAACAACAGCTCAGAACAACGTGTCTCTCTGGACATTGACCTCTGGGACAAGTTCAGTGAACTCTCCAC
CAAGTGCATCATTAAGACTGTGGAGTTCGCCAAGCAGCTGCCCGGCTTCACCACCCTCACCATCGCCGACCAGATCACCCTCCTCAAGGC
TGCCTGCCTGGACATCCTGATCCTGCGGATCTGCACGCGGTACACGCCCGAGCAGGACACCATGACCTTCTCGGACGGGCTGACCCTGAA
CCGGACCCAGATGCACAACGCTGGCTTCGGCCCCCTCACCGACCTGGTCTTTGCCTTCGCCAACCAGCTGCTGCCCCTGGAGATGGATGA
TGCGGAGACGGGGCTGCTCAGCGCCATCTGCCTCATCTGCGGAGACCGCCAGGACCTGGAGCAGCCGGACCGGGTGGACATGCTGCAGGA
GCCGCTGCTGGAGGCGCTAAAGGTCTACGTGCGGAAGCGGAGGCCCAGCCGCCCCCACATGTTCCCCAAGATGCTAATGAAGATTACTGA
CCTGCGAAGCATCAGCGCCAAGGGGGCTGAGCGGGTGATCACGCTGAAGATGGAGATCCCGGGCTCCATGCCGCCTCTCATCCAGGAAAT
GTTGGAGAACTCAGAGGGCCTGGACACTCTGAGCGGACAGCCGGGGGGTGGGGGGCGGGACGGGGGTGGCCTGGCCCCCCCGCCAGGCAG
CTGTAGCCCCAGCCTCAGCCCCAGCTCCAACAGAAGCAGCCCGGCCACCCACTCCCCGTGACCGCCCACGCCACATGGACACAGCCCTCG
CCCTCCGCCCCGGCTTTTCTCTGCCTTTCTACCGACCATGTGACCCCGCACCAGCCCTGCCCCCACCTGCCCTCCCGGGCAGTACTGGGG
ACCTTCCCTGGGGGACGGGGAGGGAGGAGGCAGCGACTCCTTGGACAGAGGCCTGGGCCCTCAGTGGACTGCCTGCTCCCACAGCCTGGG
CTGACGTCAGAGGCCGAGGCCAGGAACTGAGTGAGGCCCCTGGTCCTGGGTCTCAGGATGGGTCCTGGGGGCCTCGTGTTCATCAAGACA
CCCCTCTGCCCAGCTCACCACATCTTCATCACCAGCAAACGCCAGGACTTGGCTCCCCCATCCTCAGAACTCACAAGCCATTGCTCCCCA
GCTGGGGAACCTCAACCTCCCCCCTGCCTCGGTTGGTGACAGAGGGGGTGGGACAGGGGCGGGGGGTTCCCCCTGTACATACCCTGCCAT
ACCAACCCCAGGTATTAATTCTCGCTGGTTTTGTTTTTATTTTAATTTTTTTGTTTTGATTTTTTTAATAAGAATTTTCATTTTAAGCAC

>In-frame_BCOR_ENST00000378444_chrX_39914621_-_RARA_ENST00000394089_chr17_38504566_+_6286nt
GCTCGCCGCGCTTCTCCGGCCCGGCTCCTTCTCCGCTCGTTAACGTCGCCAACCCCCCCCACCCCTCATATCTCTCTCCACCCACCCAAC
CGCCCCCCGCTCCTTCTCGCCGCCTCGAGTCCGCTTGGGGGAAAACTTCAAAGAGCCGGATCGCAGGCTCCCTGCCTACTCCCCCACCGG
GGATTTCAGACTAGACGCTTGAAGCAAAGCTGCCATCCCAGAAGACGACATGCTCTCAGCAACCCCCCTGTATGGGAACGTTCACAGCTG
GATGAACAGCGAGAGGGTCCGCATGTGTGGGGCGAGCGAAGACAGGAAAATCCTTGTAAATGATGGTGACGCTTCAAAAGCCAGACTGGA
ACTGAGGGAAGAGAATCCCTTGAACCACAACGTGGTGGATGCGAGCACGGCCCATAGGATCGATGGCCTGGCAGCACTGAGCATGGACCG
CACTGGCCTGATCCGGGAAGGGCTGCGGGTCCCGGGAAACATCGTCTATTCTAGCTTGTGTGGACTGGGCTCAGAGAAAGGTCGGGAGGC
TGCCACAAGCACTCTAGGTGGCCTTGGGTTTTCTTCGGAAAGAAATCCAGAGATGCAGTTCAAACCGAATACACCCGAGACAGTGGAGGC
TTCTGCCGTCTCTGGAAAACCCCCAAATGGCTTCAGTGCTATATACAAAACACCGCCTGGAATACAAAAAAGTGCTGTAGCCACAGCAGA
AGCGCTGGGCTTGGACAGGCCTGCCAGCGACAAACAGAGCCCTCTCAACATCAATGGTGCTAGTTATCTGCGGCTGCCCTGGGTCAATCC
TTACATGGAGGGTGCCACGCCAGCCATCTACCCTTTCCTCGACTCGCCAAATAAGTATTCACTGAACATGTACAAGGCCTTGCTACCTCA
GCAGTCCTACAGCTTGGCCCAGCCGCTGTATTCTCCAGTCTGCACCAATGGGGAGCGCTTTCTCTACCTGCCGCCACCTCACTACGTCGG
TCCCCACATCCCATCGTCCTTGGCATCACCCATGAGGCTCTCGACACCTTCGGCCTCCCCAGCCATCCCGCCTCTCGTCCATTGCGCAGA
CAAAAGCCTCCCGTGGAAGATGGGCGTCAGCCCTGGGAATCCTGTTGATTCCCACGCCTATCCTCACATCCAGAACAGTAAGCAGCCCAG
GGTTCCCTCTGCCAAGGCGGTCACCAGTGGCCTGCCGGGGGACACAGCTCTCCTGTTGCCCCCCTCGCCTCGGCCGTCACCCCGAGTCCA
CCTTCCCACCCAGCCTGCTGCAGACACCTACTCGGAGTTCCACAAGCACTATGCCAGGATCTCCACCTCTCCTTCAGTTGCCCTGTCAAA
GCCATACATGACAGTTAGCAGCGAGTTCCCCGCGGCCAGGCTCTCCAATGGCAAGTATCCCAAGGCTCCGGAAGGGGGCGAAGGTGCCCA
GCCAGTGCCCGGGCATGCCCGGAAGACAGCGGTTCAAGACAGAAAAGATGGCAGCTCACCTCCTCTGTTGGAGAAGCAGACCGTTACCAA
AGACGTCACAGATAAGCCACTAGACTTGTCTTCTAAAGTGGTGGATGTAGATGCTTCCAAAGCTGACCACATGAAAAAGATGGCTCCCAC
GGTCCTGGTTCACAGCAGGGCTGGAAGTGGCTTAGTGCTCTCCGGAAGTGAGATTCCGAAAGAAACACTATCTCCTCCAGGAAATGGTTG
TGCTATCTATAGATCTGAAATCATCAGCACTGCTCCCTCATCCTGGGTGGTGCCCGGGCCAAGTCCTAACGAAGAGAACAATGGCAAAAG
CATGTCGCTGAAAAACAAGGCATTGGACTGGGCGATACCACAGCAGCGGAGTTCATCATGCCCGCGCATGGGCGGCACCGATGCTGTCAT
CACTAACGTTTCAGGGTCAGTGTCGAGTGCAGGCCGCCCAGCCTCCGCATCACCCGCCCCCAATGCCAATGCAGATGGCACCAAAACCAG
CAGGAGCTCTGTAGAAACCACACCATCCGTTATTCAGCACGTGGGCCAGCCCCCGGCCACTCCTGCCAAGCACAGTAGCAGCACCAGCAG
CAAGGGCGCCAAAGCCAGCAACCCAGAACCGAGTTTCAAAGCAAACGAGAACGGCCTTCCACCAAGCTCTATATTTCTGTCTCCAAATGA
GGCATTCAGGTCCCCACCAATTCCCTACCCCAGGAGTTACCTCCCTTACCCAGCCCCTGAGGGCATTGCTGTAAGTCCCCTCTCCTTACA
TGGCAAAGGACCTGTCTACCCTCACCCAGTTTTGTTACCCAATGGCAGTCTGTTTCCTGGGCACCTTGCCCCAAAGCCTGGGCTGCCCTA
TGGGCTTCCCACCGGCCGTCCAGAGTTTGTGACCTACCAAGATGCCCTGGGGTTGGGCATGGTGCATCCCATGTTGATACCACACACGCC
CATAGAGATTACTAAAGAGGAGAAACCAGAGAGGAGATCCCGGTCCCATGAGAGAGCCCGTTACGAGGACCCAACCCTCCGGAATCGGTT
TTCCGAGATTTTGGAAACTAGCAGCACCAAGTTACATCCAGATGTCCCCACCGACAAGAACCTAAAGCCGAACCCCAACTGGAATCAAGG
GAAGACTGTTGTCAAAAGCGACAAGCTTGTCTACGTAGACCTTCTCCGAGAAGAACCAGATGCTAAAACTGACACAAACGTGTCCAAACC
CAGCTTTGCAGCAGAGAGTGTTGGCCAGAGCGCTGAGCCCCCCAAGCCCTCAGTTGAGCCGGCCCTGCAGCAGCACCGTGATTTCATCGC
CCTGAGAGAGGAGTTGGGGCGCATCAGTGACTTCCACGAAACTTATACTTTCAAACAGCCAGTCTTCACCGTAAGCAAGGACAGTGTTCT
GGCAGGTACCAACAAAGAGAACCTAGGGTTGCCAGTCTCGACTCCATTCCTGGAGCCACCTCTGGGGAGCGATGGCCCTGCTGTAACTTT
TGGTAAAACCCAAGAGGATCCCAAACCATTTTGTGTGGGCAGTGCCCCACCAAGTGTGGATGTGACCCCCACCTATACCAAAGATGGAGC
TGATGAGGCTGAATCAAATGATGGCAAAGTTCTGAAACCGAAGCCATCTAAGCTGGCAAAGAGAATCGCCAACTCAGCGGGTTACGTGGG
TGACCGATTCAAATGTGTCACTACCGAACTGTATGCAGATTCCAGTCAGCTCAGCCGGGAGCAACGGGCATTGCAGATGGAAGGATTACA
AGAGGACAGTATTTTATGTCTACCCGCTGCTTACTGTGAGCGTGCAATGATGCGCTTCTCAGAGTTGGAGATGAAAGAAAGAGAAGGTGG
CCACCCAGCAACCAAAGACTCCGAGATGTGCAAATTCAGCCCAGCCGACTGGGAAAGGTTGAAAGGAAATCAGGACAAAAAGCCAAAGTC
GGTCACCCTGGAGGAGGCCATTGCAGAACAGAACGAAAGTGAGAGATGCGAGTATAGTGTTGGAAACAAGCACCGTGATCCCTTTGAAGC
CCCAGAGGACAAAGATCTTCCTGTGGAGAAGTACTTTGTGGAGAGGCAGCCTGTGAGCGAGCCTCCCGCAGACCAGGTGGCCTCGGACAT
GCCTCACAGCCCCACCCTCCGGGTGGACAGGAAACGCAAAGTCTCAGGTGACAGCAGCCACACTGAGACCACTGCGGAGGAGGTGCCAGA
GGACCCTCTGCTGAAAGCCAAACGCCGACGAGTCTCTAAAGATGACTGGCCTGAGAGGGAAATGACAAACAGTTCCTCTAACCACTTAGA
AGACCCACATTATAGTGAGCTGACCAACCTGAAGGTGTGCATTGAATTAACAGGGCTCCATCCTAAAAAACAACGCCACTTGCTGCACCT
TAGAGAACGATGGGAGCAGCAGGTGTCGGCAGCAGATGGCAAACCTGGCCGGCAAAGCAGGAAGGAAGTGACCCAGGCCACTCAGCCTGA
GGCCATTCCTCAGGGGACTAACATCACTGAAGAGAAACCTGGCAGGAAAAGGGCAGAGGCCAAAGGCAACAGAAGCTGGTCGGAAGAGTC
TCTTAAACCCAGTGACAATGAACAAGGCTTGCCTGTGTTCTCCGGCTCTCCGCCCATGAAGAGTCTTTCATCCACCAGTGCAGGCGGCAA
AAAGCAGGCTCAGCCAAGCTGCGCACCAGCCTCCAGGCCGCCTGCCAAACAGCAGAAAATTAAAGAAAACCAGAAGACAGATGTGCTGTG
TGCAGACGAAGAAGAGGATTGCCAGGCTGCCTCCCTGCTGCAGAAATACACCGACAACAGCGAGAAGCCATCCGGGAAGAGACTGTGCAA
AACCAAACACTTGATCCCTCAGGAGTCCAGGCGGGGATTGCCACTGACAGGGGAATACTACGTGGAGAATGCCGATGGCAAGGTGACTGT
CCGGAGATTCAGAAAGCGGCCGGAGCCCAGTTCGGACTATGATCTGTCACCAGCCAAGCAGGAGCCAAAGCCCTTCGACCGCTTGCAGCA
ACTGCTACCAGCCTCCCAGTCCACACAGCTGCCATGCTCAAGTTCCCCTCAGGAGACCACCCAGTCTCGCCCTATGCCGCCGGAAGCACG
GAGACTTATTGTCAATAAGAACGCTGGCGAGACCCTTCTGCAGCGGGCAGCCAGGCTTGGCTATGAGGAAGTGGTCCTGTACTGCTTAGA
GAACAAGATTTGTGATGTAAATCATCGGGACAACGCAGGTTACTGCGCCCTGCATGAAGCTTGTGCTAGGGGCTGGCTCAACATTGTGCG
ACACCTCCTTGAATATGGCGCTGATGTCAACTGTAGTGCCCAGGATGGAACCAGGCCTCTGCACGATGCTGTTGAGAACGATCACTTGGA
AATTGTCCGACTACTTCTCTCTTATGGTGCTGACCCCACCTTGGCTACGTACTCAGGTAGAACCATCATGAAAATGACCCACAGTGAACT
TATGGAAAAGTTCTTAACAGCCATTGAGACCCAGAGCAGCAGTTCTGAAGAGATAGTGCCCAGCCCTCCCTCGCCACCCCCTCTACCCCG
CATCTACAAGCCTTGCTTTGTCTGTCAGGACAAGTCCTCAGGCTACCACTATGGGGTCAGCGCCTGTGAGGGCTGCAAGGGCTTCTTCCG
CCGCAGCATCCAGAAGAACATGGTGTACACGTGTCACCGGGACAAGAACTGCATCATCAACAAGGTGACCCGGAACCGCTGCCAGTACTG
CCGACTGCAGAAGTGCTTTGAAGTGGGCATGTCCAAGGAGTCTGTGAGAAACGACCGAAACAAGAAGAAGAAGGAGGTGCCCAAGCCCGA
GTGCTCTGAGAGCTACACGCTGACGCCGGAGGTGGGGGAGCTCATTGAGAAGGTGCGCAAAGCGCACCAGGAAACCTTCCCTGCCCTCTG
CCAGCTGGGCAAATACACTACGAACAACAGCTCAGAACAACGTGTCTCTCTGGACATTGACCTCTGGGACAAGTTCAGTGAACTCTCCAC
CAAGTGCATCATTAAGACTGTGGAGTTCGCCAAGCAGCTGCCCGGCTTCACCACCCTCACCATCGCCGACCAGATCACCCTCCTCAAGGC
TGCCTGCCTGGACATCCTGATCCTGCGGATCTGCACGCGGTACACGCCCGAGCAGGACACCATGACCTTCTCGGACGGGCTGACCCTGAA
CCGGACCCAGATGCACAACGCTGGCTTCGGCCCCCTCACCGACCTGGTCTTTGCCTTCGCCAACCAGCTGCTGCCCCTGGAGATGGATGA
TGCGGAGACGGGGCTGCTCAGCGCCATCTGCCTCATCTGCGGAGACCGCCAGGACCTGGAGCAGCCGGACCGGGTGGACATGCTGCAGGA
GCCGCTGCTGGAGGCGCTAAAGGTCTACGTGCGGAAGCGGAGGCCCAGCCGCCCCCACATGTTCCCCAAGATGCTAATGAAGATTACTGA
CCTGCGAAGCATCAGCGCCAAGGGGGCTGAGCGGGTGATCACGCTGAAGATGGAGATCCCGGGCTCCATGCCGCCTCTCATCCAGGAAAT
GTTGGAGAACTCAGAGGGCCTGGACACTCTGAGCGGACAGCCGGGGGGTGGGGGGCGGGACGGGGGTGGCCTGGCCCCCCCGCCAGGCAG
CTGTAGCCCCAGCCTCAGCCCCAGCTCCAACAGAAGCAGCCCGGCCACCCACTCCCCGTGACCGCCCACGCCACATGGACACAGCCCTCG


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FusionGenePPI for BCOR_RARA


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check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
BCORMLLT3, BCL6, HDAC1, HDAC3, HDAC4, HDAC6, PCGF1, KDM2B, HSPA4, RING1, RNF2, RYBP, SKP1, ZBTB7A, SP1, MLLT1, BCOR, YAF2, NACC1, USP7, PCGF3, UBTD1, NCOR2, NAA10, PCGF5, EED, CBX7, QPRT, CARD8, DCAF15, CLEC11A, CTBP1, FBXW11, B9D2, HSPD1, TRIM27, TCF3, KCNAB2, NFS1, PTPN1, HMG20A, IPO8, DNAJC11, RNASEH2B, ACTL8, CCDC124, ESR1, ACACB, AK2, ANGEL2, ATG101, C10orf131, CCDC101, CDK2AP1, CS, DDB1, DYNC1LI1, EIF3D, ERCC8, IBTK, IDH3G, ING4, KDELR2, LETMD1, NAA50, NAP1L4, NCAPD2, NSF, OTX2, PCGF2, PCMT1, PQBP1, PRCP, SALL1, SATB2, SCAF11, SENP2, SMC4, TCEB1, TCP1, TIA1, TKT, TMTC1, TRPM1, USP42, EYA2, HAO2, ERP44, SIRT6, L3MBTL1, NCAPH2, CDC16, CELA1, IL17RA, CSN1S1, C6orf141, PRR20E, NR3C1, AR, TRIM25RARANRBF2, ZBTB16, MECR, RXRG, RXRB, NCOA6, GADD45G, GADD45A, NRIP1, KAT2B, HDAC3, HDAC4, TDG, PML, TRIP4, KDM5A, RXRA, POU2F1, NCOR2, NR0B2, BAG1, TADA3, NCOR1, NKX2-1, TRIM24, IRX4, SP1, NPAS2, CLOCK, ARNTL, NR2E3, CCND3, NCOA2, SRC, AJUBA, LIMD1, WTIP, SKI, HR, PIN1, SUV39H1, PSMC5, EP300, PARP1, MED6, TOP2B, SAP130, HNRNPU, RFC4, NPM1, MRTO4, SNRNP40, MED1, NCOA1, HMGA1, RUVBL1, RUNX1, SIAH1, RARA, HDAC2, NCOA3, CREBBP, LRIF1, KLF5, SMARCD3, ARID1A, SPI1, PRDX6, NR1H2, ITGB1BP2, MED25, MAPK6, FOXO1, MAPK1, TRIM32, PHF8, TNIP1, HACE1, SQSTM1, UBQLN1, ARID5A, UBE3A, PRAM1, FAS, PRAME, TBL1XR1, SUZ12, EZH2, USP7, TMEM54, MMS19, AKT1, FN1, WWOX, E2F1, MBD3, MTA2, CBX5, CEBPA, HDAC1, NSD1, TEKT4, SNW1, SIRT1, ACTN4, SRF, MDM2, ZNF131, RARG, RARB, TRIM25


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for BCOR_RARA


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneRARAP10276DB00210AdapaleneRetinoic acid receptor alphasmall moleculeapproved
TgeneRARAP10276DB00459AcitretinRetinoic acid receptor alphasmall moleculeapproved
TgeneRARAP10276DB00982IsotretinoinRetinoic acid receptor alphasmall moleculeapproved
TgeneRARAP10276DB00523AlitretinoinRetinoic acid receptor alphasmall moleculeapproved|investigational
TgeneRARAP10276DB00799TazaroteneRetinoic acid receptor alphasmall moleculeapproved|investigational
TgeneRARAP10276DB00755TretinoinRetinoic acid receptor alphasmall moleculeapproved|investigational|nutraceutical

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RelatedDiseases for BCOR_RARA


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneBCORC1846265Microphthalmia, syndromic 22CTD_human;ORPHANET;UNIPROT
HgeneBCORC0010606Adenoid Cystic Carcinoma1CTD_human
HgeneBCORC0022665Kidney Neoplasm1CTD_human
HgeneBCORC0029463Osteosarcoma1CTD_human
HgeneBCORC0206651Sarcoma, Clear Cell1CTD_human
TgeneRARAC0023487Acute Promyelocytic Leukemia22CTD_human;HPO;ORPHANET
TgeneRARAC0036341Schizophrenia3PSYGENET
TgeneRARAC0005586Bipolar Disorder1PSYGENET
TgeneRARAC0010701Phyllodes Tumor1CTD_human
TgeneRARAC0085183Neoplasms, Second Primary1CTD_human
TgeneRARAC0149940Sciatic Neuropathy1CTD_human
TgeneRARAC0206650Fibroadenoma1CTD_human
TgeneRARAC0525045Mood Disorders1PSYGENET
TgeneRARAC1458155Mammary Neoplasms1CTD_human
TgeneRARAC2239176Liver carcinoma1CTD_human