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Fusion gene ID: 4050 |
FusionGeneSummary for BCL7A_GLTSCR1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: BCL7A_GLTSCR1 | Fusion gene ID: 4050 | Hgene | Tgene | Gene symbol | BCL7A | GLTSCR1 | Gene ID | 605 |
| Gene name | BCL tumor suppressor 7A | ||
| Synonyms | BCL7 | ||
| Cytomap | 12q24.31 | ||
| Type of gene | protein-coding | ||
| Description | B-cell CLL/lymphoma 7 protein family member AB-cell CLL/lymphoma 7AB-cell CLL/lymphoma-7 | ||
| Modification date | 20180519 | ||
| UniProtAcc | Q4VC05 | ||
| Ensembl transtripts involved in fusion gene | ENST00000538010, ENST00000261822, | ENST00000396720, | |
| Fusion gene scores | * DoF score | 5 X 4 X 5=100 | 4 X 4 X 3=48 |
| # samples | 5 | 4 | |
| ** MAII score | log2(5/100*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: BCL7A [Title/Abstract] AND GLTSCR1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. Tumor suppressor gene involved fusion gene, retained protein feature but frameshift. DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | UCEC | TCGA-B5-A5OE-01A | BCL7A | chr12 | 122492832 | + | GLTSCR1 | chr19 | 48197372 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000538010 | ENST00000396720 | BCL7A | chr12 | 122492832 | + | GLTSCR1 | chr19 | 48197372 | + |
| In-frame | ENST00000261822 | ENST00000396720 | BCL7A | chr12 | 122492832 | + | GLTSCR1 | chr19 | 48197372 | + |
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FusionProtFeatures for BCL7A_GLTSCR1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| BCL7A | GLTSCR1 |
| Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >GLTSCR1 | chr12:122492832 | chr19:48197372 | ENST00000396720 | + | 6 | 15 | 1265_1276 | 761 | 1561 | Compositional bias | Note=Poly-Ser |
| Tgene | >GLTSCR1 | chr12:122492832 | chr19:48197372 | ENST00000396720 | + | 6 | 15 | 1333_1337 | 761 | 1561 | Compositional bias | Note=Poly-Pro |
| Tgene | >GLTSCR1 | chr12:122492832 | chr19:48197372 | ENST00000396720 | + | 6 | 15 | 1345_1355 | 761 | 1561 | Compositional bias | Note=Poly-Pro |
| Tgene | >GLTSCR1 | chr12:122492832 | chr19:48197372 | ENST00000396720 | + | 6 | 15 | 935_940 | 761 | 1561 | Compositional bias | Note=Poly-Pro |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | GLTSCR1 | chr12:122492832 | chr19:48197372 | ENST00000396720 | + | 6 | 15 | 88_96 | 761 | 1561 | Compositional bias | Note=Poly-Gly |
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FusionGeneSequence for BCL7A_GLTSCR1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_BCL7A_ENST00000538010_chr12_122492832_+_GLTSCR1_ENST00000396720_chr19_48197372_+_1008aa MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKNKNKKKGKDEKCGSEVTTPENSSSPGMMDMH DDNSNQSSIADASPIKQENSSNSSPAPEPNSAVPSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPSGDSGLAA ETSAISQVPRSRSQRGSQIGREPIGLSGIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCP PPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPS QGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSG QAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQG SVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEE KTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSS SSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTV DHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAA SAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEA >In-frame_BCL7A_ENST00000261822_chr12_122492832_+_GLTSCR1_ENST00000396720_chr19_48197372_+_987aa MSGRSVRAETRSRAKDDIKRVMAAIEKVRKWEKKWVTVGDTSLRIYKWVPVTEPKVDDKNKNKKKGKDEKCGSEVTTPENSSSPGMMDMH DDNSNQSSIADASPIKQENSSNSSPAPEPNSAVPSDGTEAKVDEAQADGKEHPGAEDASDEQNSQSSMEHSMNSSEKVDRQPSGDSGLAA ETSAISQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVP PPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAA PPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAA TGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRL LPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSS SRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNR PPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPR LPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_BCL7A_ENST00000538010_chr12_122492832_+_GLTSCR1_ENST00000396720_chr19_48197372_+_3024nt ATGTCGGGCAGGTCGGTTCGAGCCGAGACGAGGAGCCGGGCCAAAGATGATATCAAGAGGGTCATGGCGGCGATCGAGAAAGTGCGCAAA TGGGAGAAGAAATGGGTGACCGTTGGTGACACATCCCTACGAATCTACAAATGGGTCCCTGTGACGGAGCCCAAGGTTGATGACAAAAAC AAGAATAAGAAAAAAGGCAAGGACGAGAAGTGTGGCTCAGAGGTGACCACTCCGGAGAACAGTTCCTCCCCAGGGATGATGGACATGCAT GACGATAACAGCAACCAGAGCTCCATCGCAGATGCCTCCCCCATCAAACAGGAGAACAGCAGCAACTCCAGCCCCGCTCCAGAGCCCAAC TCGGCTGTGCCCAGCGACGGCACCGAGGCCAAGGTGGATGAGGCCCAGGCTGATGGGAAGGAGCACCCAGGAGCTGAAGATGCTTCTGAT GAGCAGAATTCACAGTCCTCGATGGAACATTCGATGAACAGCTCAGAGAAAGTAGATCGGCAGCCGTCTGGAGACTCGGGTCTGGCCGCA GAGACGTCTGCAATCTCTCAGGTACCTCGCTCGAGGTCTCAGAGGGGCAGCCAGATCGGCCGGGAGCCCATTGGGTTGTCGGGGATCCCG GCAGCGGCTCCGCTGAAGGGCCCAGGCCCCTCTTCGTCCCCGTCACTACCTCACCAGGCCCCTCTGGGGGACAGCCCCCACCTGCCCTCC CCACACCCCACCCGGCCCCCTTCCCGCCCACCCTCCCGGCCACAGAGTGTGTCCCGCCCTCCCTCAGAGCCACCCTTGCACCCTTGCCCC CCACCCCAGGCCCCCCCAACTCTGCCTGGCATCTTTGTCATCCAAAACCAGCTAGGCGTTCCCCCGCCTGCCAGCAACCCGGCCCCTACT GCCCCAGGCCCGCCGCAGCCGCCTCTCCGCCCCCAGTCCCAGCCGCCTGAGGGACCGCTGCCCCCAGCCCCCCACCTCCCTCCATCCTCC ACCTCCTCTGCTGTGGCCTCCTCCTCTGAGACGTCCTCCAGGTTGCCAGCCCCTACGCCATCCGACTTCCAGCTCCAGTTCCCACCCAGC CAGGGGCCCCACAAGTCCCCCACTCCCCCTCCAACCCTCCACCTGGTCCCTGAGCCGGCAGCACCCCCCCCACCGCCTCCTCGGACCTTC CAGATGGTGACCACCCCCTTCCCAGCGCTGCCCCAGCCGAAGGCTCTTCTCGAGAGATTTCACCAGGTGCCGTCCGGAATCATCCTCCAG AACAAGGCTGGGGGGGCCCCTGCCGCCCCGCAGACCTCCACCAGCCTGGGGCCCCTCACCAGCCCCGCTGCGTCTGTGCTGGTCAGTGGG CAGGCCCCATCTGGGACCCCCACTGCCCCCAGCCACGCCCCCGCCCCGGCACCCATGGCCGCCACAGGCCTCCCTCCTCTGCTTCCAGCC GAGAACAAGGCTTTTGCCAGCAACCTCCCGACCCTGAATGTGGCCAAGGCCGCTTCCTCCGGGCCAGGGAAGCCCTCCGGGCTGCAGTAT GAGAGCAAACTGAGTGGCCTGAAGAAGCCCCCCACGCTTCAGCCCAGCAAGGAAGCCTGTTTCCTGGAGCATTTGCACAAACACCAGGGC TCCGTCCTGCACCCCGACTACAAGACGGCCTTCCCCTCCTTTGAGGACGCCCTGCATCGCCTCCTGCCCTACCATGTCTACCAGGGCGCC CTCCCCTCCCCCAGTGACTACCACAAAGTGGACGAGGAGTTTGAGACGGTCTCCACGCAGCTGCTGAAACGCACCCAGGCCATGCTCAAT AAATATCGGCTCCTGCTCCTGGAGGAGTCCCGGAGGGTGAGCCCCTCAGCGGAGATGGTAATGATCGACCGAATGTTCATTCAGGAGGAG AAGACCACCCTTGCCTTGGATAAACAGCTGGCCAAGGAGAAGCCGGACGAGTACGTGTCTTCCTCCCGCTCGCTCGGCCTCCCCATCGCA GCCTCTTCCGAGGGTCATCGGCTTCCCGGCCACGGCCCCCTGTCGTCTTCAGCTCCCGGGGCCTCCACCCAGCCCCCTCCACACCTGCCC ACCAAGCTTGTGATCCGGCACGGCGGGGCAGGCGGCTCCCCTTCGGTCACCTGGGCCCGGGCGTCCTCCTCCCTGTCCTCCTCTTCCTCC TCCTCCTCTGCCGCCTCCTCCTTGGACGCCGACGAGGACGGCCCCATGCCCTCCCGCAACCGCCCGCCCATCAAGACCTACGAGGCCCGG AGCCGCATCGGGCTCAAGCTCAAGATCAAGCAGGAAGCCGGGCTCAGCAAGGTCGTGCACAACACGGCCCTGGACCCCGTGCACCAGCCC CCGCCACCCCCCGCTACCCTCAAGGTGGCCGAGCCCCCGCCACGGCCGCCACCACCACCGCCGCCCACGGGCCAGATGAACGGCACGGTG GACCACCCGCCGCCTGCCGCCCCCGAGCGCAAGCCCCTGGGCACCGCCCCGCACTGCCCGCGCCTGCCACTGCGCAAGACCTACCGCGAG AACGTGGGGGGCCCTGGCGCGCCGGAGGGGACGCCCGCAGGCAGGGCACGGGGAGGCAGCCCGGCGCCGCTGCCCGCCAAAGTGGACGAG GCCACCAGCGGGCTCATCCGCGAGCTGGCGGCCGTGGAGGACGAGCTGTACCAGCGTATGCTGAAGGGCCCCCCGCCAGAGCCCGCAGCC AGCGCCGCCCAAGGCACCGGGGACCCCGACTGGGAGGCGCCCGGGCTGCCCCCTGCCAAGCGGCGCAAGTCCGAGTCGCCCGACGTGGAC CAGGCCAGCTTCTCCAGCGACAGCCCGCAGGATGACACGCTCACCGAGCACCTGCAGAGCGCCATCGACAGCATCCTGAACCTGCAGCAG GCCCCCGGCCGGACGCCCGCGCCCTCGTACCCCCACGCTGCCTCGGCCGGCACCCCCGCATCCCCGCCGCCCCTGCACAGGCCCGAGGCC >In-frame_BCL7A_ENST00000261822_chr12_122492832_+_GLTSCR1_ENST00000396720_chr19_48197372_+_2961nt ATGTCGGGCAGGTCGGTTCGAGCCGAGACGAGGAGCCGGGCCAAAGATGATATCAAGAGGGTCATGGCGGCGATCGAGAAAGTGCGCAAA TGGGAGAAGAAATGGGTGACCGTTGGTGACACATCCCTACGAATCTACAAATGGGTCCCTGTGACGGAGCCCAAGGTTGATGACAAAAAC AAGAATAAGAAAAAAGGCAAGGACGAGAAGTGTGGCTCAGAGGTGACCACTCCGGAGAACAGTTCCTCCCCAGGGATGATGGACATGCAT GACGATAACAGCAACCAGAGCTCCATCGCAGATGCCTCCCCCATCAAACAGGAGAACAGCAGCAACTCCAGCCCCGCTCCAGAGCCCAAC TCGGCTGTGCCCAGCGACGGCACCGAGGCCAAGGTGGATGAGGCCCAGGCTGATGGGAAGGAGCACCCAGGAGCTGAAGATGCTTCTGAT GAGCAGAATTCACAGTCCTCGATGGAACATTCGATGAACAGCTCAGAGAAAGTAGATCGGCAGCCGTCTGGAGACTCGGGTCTGGCCGCA GAGACGTCTGCAATCTCTCAGATCCCGGCAGCGGCTCCGCTGAAGGGCCCAGGCCCCTCTTCGTCCCCGTCACTACCTCACCAGGCCCCT CTGGGGGACAGCCCCCACCTGCCCTCCCCACACCCCACCCGGCCCCCTTCCCGCCCACCCTCCCGGCCACAGAGTGTGTCCCGCCCTCCC TCAGAGCCACCCTTGCACCCTTGCCCCCCACCCCAGGCCCCCCCAACTCTGCCTGGCATCTTTGTCATCCAAAACCAGCTAGGCGTTCCC CCGCCTGCCAGCAACCCGGCCCCTACTGCCCCAGGCCCGCCGCAGCCGCCTCTCCGCCCCCAGTCCCAGCCGCCTGAGGGACCGCTGCCC CCAGCCCCCCACCTCCCTCCATCCTCCACCTCCTCTGCTGTGGCCTCCTCCTCTGAGACGTCCTCCAGGTTGCCAGCCCCTACGCCATCC GACTTCCAGCTCCAGTTCCCACCCAGCCAGGGGCCCCACAAGTCCCCCACTCCCCCTCCAACCCTCCACCTGGTCCCTGAGCCGGCAGCA CCCCCCCCACCGCCTCCTCGGACCTTCCAGATGGTGACCACCCCCTTCCCAGCGCTGCCCCAGCCGAAGGCTCTTCTCGAGAGATTTCAC CAGGTGCCGTCCGGAATCATCCTCCAGAACAAGGCTGGGGGGGCCCCTGCCGCCCCGCAGACCTCCACCAGCCTGGGGCCCCTCACCAGC CCCGCTGCGTCTGTGCTGGTCAGTGGGCAGGCCCCATCTGGGACCCCCACTGCCCCCAGCCACGCCCCCGCCCCGGCACCCATGGCCGCC ACAGGCCTCCCTCCTCTGCTTCCAGCCGAGAACAAGGCTTTTGCCAGCAACCTCCCGACCCTGAATGTGGCCAAGGCCGCTTCCTCCGGG CCAGGGAAGCCCTCCGGGCTGCAGTATGAGAGCAAACTGAGTGGCCTGAAGAAGCCCCCCACGCTTCAGCCCAGCAAGGAAGCCTGTTTC CTGGAGCATTTGCACAAACACCAGGGCTCCGTCCTGCACCCCGACTACAAGACGGCCTTCCCCTCCTTTGAGGACGCCCTGCATCGCCTC CTGCCCTACCATGTCTACCAGGGCGCCCTCCCCTCCCCCAGTGACTACCACAAAGTGGACGAGGAGTTTGAGACGGTCTCCACGCAGCTG CTGAAACGCACCCAGGCCATGCTCAATAAATATCGGCTCCTGCTCCTGGAGGAGTCCCGGAGGGTGAGCCCCTCAGCGGAGATGGTAATG ATCGACCGAATGTTCATTCAGGAGGAGAAGACCACCCTTGCCTTGGATAAACAGCTGGCCAAGGAGAAGCCGGACGAGTACGTGTCTTCC TCCCGCTCGCTCGGCCTCCCCATCGCAGCCTCTTCCGAGGGTCATCGGCTTCCCGGCCACGGCCCCCTGTCGTCTTCAGCTCCCGGGGCC TCCACCCAGCCCCCTCCACACCTGCCCACCAAGCTTGTGATCCGGCACGGCGGGGCAGGCGGCTCCCCTTCGGTCACCTGGGCCCGGGCG TCCTCCTCCCTGTCCTCCTCTTCCTCCTCCTCCTCTGCCGCCTCCTCCTTGGACGCCGACGAGGACGGCCCCATGCCCTCCCGCAACCGC CCGCCCATCAAGACCTACGAGGCCCGGAGCCGCATCGGGCTCAAGCTCAAGATCAAGCAGGAAGCCGGGCTCAGCAAGGTCGTGCACAAC ACGGCCCTGGACCCCGTGCACCAGCCCCCGCCACCCCCCGCTACCCTCAAGGTGGCCGAGCCCCCGCCACGGCCGCCACCACCACCGCCG CCCACGGGCCAGATGAACGGCACGGTGGACCACCCGCCGCCTGCCGCCCCCGAGCGCAAGCCCCTGGGCACCGCCCCGCACTGCCCGCGC CTGCCACTGCGCAAGACCTACCGCGAGAACGTGGGGGGCCCTGGCGCGCCGGAGGGGACGCCCGCAGGCAGGGCACGGGGAGGCAGCCCG GCGCCGCTGCCCGCCAAAGTGGACGAGGCCACCAGCGGGCTCATCCGCGAGCTGGCGGCCGTGGAGGACGAGCTGTACCAGCGTATGCTG AAGGGCCCCCCGCCAGAGCCCGCAGCCAGCGCCGCCCAAGGCACCGGGGACCCCGACTGGGAGGCGCCCGGGCTGCCCCCTGCCAAGCGG CGCAAGTCCGAGTCGCCCGACGTGGACCAGGCCAGCTTCTCCAGCGACAGCCCGCAGGATGACACGCTCACCGAGCACCTGCAGAGCGCC ATCGACAGCATCCTGAACCTGCAGCAGGCCCCCGGCCGGACGCCCGCGCCCTCGTACCCCCACGCTGCCTCGGCCGGCACCCCCGCATCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_BCL7A_ENST00000538010_chr12_122492832_+_GLTSCR1_ENST00000396720_chr19_48197372_+_4190nt TCCCTTGGCTCCTTTAGGAGCTGATAGGTCATTTATTATTGGAACTGAAATGGTATAAACAATTCTCTCTCTTTTTTTCCCTTGTTAACA GCAACTTTCATTGTTAGAGAGAGGAGAGAGAGAGAAGCCTTGTTGGTTGACGTCACTTGGTTCATGAAGCCTTCGCCTAGAAGTGAAGCT GCTGAACAAACCTTGAGAAGAATCATCTCCTGCTTCAATCTGCTGCTGGATAGGAACTAATCAGAGAGAGAGAGGCGGAAGACGGAGAAG GAGGGAGTCGAAGGCTTTCCCGATCACAAATCTCACCTCCACTACAACTCTCTTTATACTTTTCTTGCAGAAATAATAATAGAAATAAGG AGGTGGTGGGGTTTCCAAAAATCTTAACCTTCAACCATCTGGGGAAAAGGCAAAAATCCCATCTACCGCAACTCTCAGTTCGAGAGTAAA GGGAGAAGAAATGGGTGACCGTTGGTGACACATCCCTACGAATCTACAAATGGGTCCCTGTGACGGAGCCCAAGGTTGATGACAAAAACA AGAATAAGAAAAAAGGCAAGGACGAGAAGTGTGGCTCAGAGGTGACCACTCCGGAGAACAGTTCCTCCCCAGGGATGATGGACATGCATG ACGATAACAGCAACCAGAGCTCCATCGCAGATGCCTCCCCCATCAAACAGGAGAACAGCAGCAACTCCAGCCCCGCTCCAGAGCCCAACT CGGCTGTGCCCAGCGACGGCACCGAGGCCAAGGTGGATGAGGCCCAGGCTGATGGGAAGGAGCACCCAGGAGCTGAAGATGCTTCTGATG AGCAGAATTCACAGTCCTCGATGGAACATTCGATGAACAGCTCAGAGAAAGTAGATCGGCAGCCGTCTGGAGACTCGGGTCTGGCCGCAG AGACGTCTGCAATCTCTCAGGTACCTCGCTCGAGGTCTCAGAGGGGCAGCCAGATCGGCCGGGAGCCCATTGGGTTGTCGGGGATCCCGG CAGCGGCTCCGCTGAAGGGCCCAGGCCCCTCTTCGTCCCCGTCACTACCTCACCAGGCCCCTCTGGGGGACAGCCCCCACCTGCCCTCCC CACACCCCACCCGGCCCCCTTCCCGCCCACCCTCCCGGCCACAGAGTGTGTCCCGCCCTCCCTCAGAGCCACCCTTGCACCCTTGCCCCC CACCCCAGGCCCCCCCAACTCTGCCTGGCATCTTTGTCATCCAAAACCAGCTAGGCGTTCCCCCGCCTGCCAGCAACCCGGCCCCTACTG CCCCAGGCCCGCCGCAGCCGCCTCTCCGCCCCCAGTCCCAGCCGCCTGAGGGACCGCTGCCCCCAGCCCCCCACCTCCCTCCATCCTCCA CCTCCTCTGCTGTGGCCTCCTCCTCTGAGACGTCCTCCAGGTTGCCAGCCCCTACGCCATCCGACTTCCAGCTCCAGTTCCCACCCAGCC AGGGGCCCCACAAGTCCCCCACTCCCCCTCCAACCCTCCACCTGGTCCCTGAGCCGGCAGCACCCCCCCCACCGCCTCCTCGGACCTTCC AGATGGTGACCACCCCCTTCCCAGCGCTGCCCCAGCCGAAGGCTCTTCTCGAGAGATTTCACCAGGTGCCGTCCGGAATCATCCTCCAGA ACAAGGCTGGGGGGGCCCCTGCCGCCCCGCAGACCTCCACCAGCCTGGGGCCCCTCACCAGCCCCGCTGCGTCTGTGCTGGTCAGTGGGC AGGCCCCATCTGGGACCCCCACTGCCCCCAGCCACGCCCCCGCCCCGGCACCCATGGCCGCCACAGGCCTCCCTCCTCTGCTTCCAGCCG AGAACAAGGCTTTTGCCAGCAACCTCCCGACCCTGAATGTGGCCAAGGCCGCTTCCTCCGGGCCAGGGAAGCCCTCCGGGCTGCAGTATG AGAGCAAACTGAGTGGCCTGAAGAAGCCCCCCACGCTTCAGCCCAGCAAGGAAGCCTGTTTCCTGGAGCATTTGCACAAACACCAGGGCT CCGTCCTGCACCCCGACTACAAGACGGCCTTCCCCTCCTTTGAGGACGCCCTGCATCGCCTCCTGCCCTACCATGTCTACCAGGGCGCCC TCCCCTCCCCCAGTGACTACCACAAAGTGGACGAGGAGTTTGAGACGGTCTCCACGCAGCTGCTGAAACGCACCCAGGCCATGCTCAATA AATATCGGCTCCTGCTCCTGGAGGAGTCCCGGAGGGTGAGCCCCTCAGCGGAGATGGTAATGATCGACCGAATGTTCATTCAGGAGGAGA AGACCACCCTTGCCTTGGATAAACAGCTGGCCAAGGAGAAGCCGGACGAGTACGTGTCTTCCTCCCGCTCGCTCGGCCTCCCCATCGCAG CCTCTTCCGAGGGTCATCGGCTTCCCGGCCACGGCCCCCTGTCGTCTTCAGCTCCCGGGGCCTCCACCCAGCCCCCTCCACACCTGCCCA CCAAGCTTGTGATCCGGCACGGCGGGGCAGGCGGCTCCCCTTCGGTCACCTGGGCCCGGGCGTCCTCCTCCCTGTCCTCCTCTTCCTCCT CCTCCTCTGCCGCCTCCTCCTTGGACGCCGACGAGGACGGCCCCATGCCCTCCCGCAACCGCCCGCCCATCAAGACCTACGAGGCCCGGA GCCGCATCGGGCTCAAGCTCAAGATCAAGCAGGAAGCCGGGCTCAGCAAGGTCGTGCACAACACGGCCCTGGACCCCGTGCACCAGCCCC CGCCACCCCCCGCTACCCTCAAGGTGGCCGAGCCCCCGCCACGGCCGCCACCACCACCGCCGCCCACGGGCCAGATGAACGGCACGGTGG ACCACCCGCCGCCTGCCGCCCCCGAGCGCAAGCCCCTGGGCACCGCCCCGCACTGCCCGCGCCTGCCACTGCGCAAGACCTACCGCGAGA ACGTGGGGGGCCCTGGCGCGCCGGAGGGGACGCCCGCAGGCAGGGCACGGGGAGGCAGCCCGGCGCCGCTGCCCGCCAAAGTGGACGAGG CCACCAGCGGGCTCATCCGCGAGCTGGCGGCCGTGGAGGACGAGCTGTACCAGCGTATGCTGAAGGGCCCCCCGCCAGAGCCCGCAGCCA GCGCCGCCCAAGGCACCGGGGACCCCGACTGGGAGGCGCCCGGGCTGCCCCCTGCCAAGCGGCGCAAGTCCGAGTCGCCCGACGTGGACC AGGCCAGCTTCTCCAGCGACAGCCCGCAGGATGACACGCTCACCGAGCACCTGCAGAGCGCCATCGACAGCATCCTGAACCTGCAGCAGG CCCCCGGCCGGACGCCCGCGCCCTCGTACCCCCACGCTGCCTCGGCCGGCACCCCCGCATCCCCGCCGCCCCTGCACAGGCCCGAGGCCT ACCCACCCTCCAGTCACAACGGTGGCCTCGGCGCCAGGACGTTGACCAGATAACACCGGGCCGCCTCCCCTTCCCCGTCCCCTCCTCCCG AAGACGCCGGGACAGTCGGGTGTCCGCCCTCAGCCTCCTGGGGACTCGAGCCGGGGATCCCCTGACGGTTTTTCTTGCCTAAGTTATTTG AGTCACAAAGGCCTCCTTCCCTGCCGCCTGCTTCAGCTGGGTTGCTGGGGGGTGGGCGTGGATTTAGGGAGGGGGCTGTGATGTAAAACG TCTCCCCTGCCAAAGGAGGGGCAAAGTGCTGTGTCAGTTCCTGTTTCTTCCCATTTCCTGGCACACTCTGCCCCTCTGTCCGGGGGACAC GCGCATGTGTTTGCCAGGGATGGGGCCACCGGGTTGATGCCAACGCTCCGGGTGCCTGTCTTGTCTGTGTGGCTTCTCAGATGGTGGAGG GTGCTGGGAGCTGGCAGGGTCCTTCCAGACAGTCTCAGCCTCTCCCCGCCGCCCCCAACAGGCTGTCAAACAAAACCGGAGAGGGGGTGG GGGAGCCAGCCTCCCAGCGTGCTGTGCCCGCAGGCACCCGTGTGACATCCGCACGTCCAGCTCCGTGACCTGTGTGTGTGTGTGTGTGCA CAAGTGAGTGAGAGATTTCGAACGCCCACCCCTCGACTTTGAAATCTGAGCAAAACAAGAAACTGGGGTCTTCCTCTCCCCCGAACCTCT CCCCAGCTAGTCTTCCCTCTGTTCTTCCTGCCTCCAGCCGCCCGCGCCAGATTTTGAAATCTCGGAGACAAAACTAGTACTGTAAGATAA >In-frame_BCL7A_ENST00000261822_chr12_122492832_+_GLTSCR1_ENST00000396720_chr19_48197372_+_3974nt ACTGGGCCAGGCGCGCGGCGGCCCCGGGCTTTGTGTGTGTGTGTATGTGTGTGTGTGTGTGTGTGTGTGTGTGAGTGTGTGCGTGTGAGA GTGCGAGTGTCTGTGCGCGAGTGAGTGAGCGGCGGGCGGGCGCGAGTGTGGCCGCCGCGGAGCGCGAGCAGGACCCGGCGGGCGCGCTCC CCAGCCTCCGTCTCCCCGCCGGAACCATGTCGGGCAGGTCGGTTCGAGCCGAGACGAGGAGCCGGGCCAAAGATGATATCAAGAGGGTCA TGGCGGCGATCGAGAAAGTGCGCAAATGGGAGAAGAAATGGGTGACCGTTGGTGACACATCCCTACGAATCTACAAATGGGTCCCTGTGA CGGAGCCCAAGGTTGATGACAAAAACAAGAATAAGAAAAAAGGCAAGGACGAGAAGTGTGGCTCAGAGGTGACCACTCCGGAGAACAGTT CCTCCCCAGGGATGATGGACATGCATGACGATAACAGCAACCAGAGCTCCATCGCAGATGCCTCCCCCATCAAACAGGAGAACAGCAGCA ACTCCAGCCCCGCTCCAGAGCCCAACTCGGCTGTGCCCAGCGACGGCACCGAGGCCAAGGTGGATGAGGCCCAGGCTGATGGGAAGGAGC ACCCAGGAGCTGAAGATGCTTCTGATGAGCAGAATTCACAGTCCTCGATGGAACATTCGATGAACAGCTCAGAGAAAGTAGATCGGCAGC CGTCTGGAGACTCGGGTCTGGCCGCAGAGACGTCTGCAATCTCTCAGATCCCGGCAGCGGCTCCGCTGAAGGGCCCAGGCCCCTCTTCGT CCCCGTCACTACCTCACCAGGCCCCTCTGGGGGACAGCCCCCACCTGCCCTCCCCACACCCCACCCGGCCCCCTTCCCGCCCACCCTCCC GGCCACAGAGTGTGTCCCGCCCTCCCTCAGAGCCACCCTTGCACCCTTGCCCCCCACCCCAGGCCCCCCCAACTCTGCCTGGCATCTTTG TCATCCAAAACCAGCTAGGCGTTCCCCCGCCTGCCAGCAACCCGGCCCCTACTGCCCCAGGCCCGCCGCAGCCGCCTCTCCGCCCCCAGT CCCAGCCGCCTGAGGGACCGCTGCCCCCAGCCCCCCACCTCCCTCCATCCTCCACCTCCTCTGCTGTGGCCTCCTCCTCTGAGACGTCCT CCAGGTTGCCAGCCCCTACGCCATCCGACTTCCAGCTCCAGTTCCCACCCAGCCAGGGGCCCCACAAGTCCCCCACTCCCCCTCCAACCC TCCACCTGGTCCCTGAGCCGGCAGCACCCCCCCCACCGCCTCCTCGGACCTTCCAGATGGTGACCACCCCCTTCCCAGCGCTGCCCCAGC CGAAGGCTCTTCTCGAGAGATTTCACCAGGTGCCGTCCGGAATCATCCTCCAGAACAAGGCTGGGGGGGCCCCTGCCGCCCCGCAGACCT CCACCAGCCTGGGGCCCCTCACCAGCCCCGCTGCGTCTGTGCTGGTCAGTGGGCAGGCCCCATCTGGGACCCCCACTGCCCCCAGCCACG CCCCCGCCCCGGCACCCATGGCCGCCACAGGCCTCCCTCCTCTGCTTCCAGCCGAGAACAAGGCTTTTGCCAGCAACCTCCCGACCCTGA ATGTGGCCAAGGCCGCTTCCTCCGGGCCAGGGAAGCCCTCCGGGCTGCAGTATGAGAGCAAACTGAGTGGCCTGAAGAAGCCCCCCACGC TTCAGCCCAGCAAGGAAGCCTGTTTCCTGGAGCATTTGCACAAACACCAGGGCTCCGTCCTGCACCCCGACTACAAGACGGCCTTCCCCT CCTTTGAGGACGCCCTGCATCGCCTCCTGCCCTACCATGTCTACCAGGGCGCCCTCCCCTCCCCCAGTGACTACCACAAAGTGGACGAGG AGTTTGAGACGGTCTCCACGCAGCTGCTGAAACGCACCCAGGCCATGCTCAATAAATATCGGCTCCTGCTCCTGGAGGAGTCCCGGAGGG TGAGCCCCTCAGCGGAGATGGTAATGATCGACCGAATGTTCATTCAGGAGGAGAAGACCACCCTTGCCTTGGATAAACAGCTGGCCAAGG AGAAGCCGGACGAGTACGTGTCTTCCTCCCGCTCGCTCGGCCTCCCCATCGCAGCCTCTTCCGAGGGTCATCGGCTTCCCGGCCACGGCC CCCTGTCGTCTTCAGCTCCCGGGGCCTCCACCCAGCCCCCTCCACACCTGCCCACCAAGCTTGTGATCCGGCACGGCGGGGCAGGCGGCT CCCCTTCGGTCACCTGGGCCCGGGCGTCCTCCTCCCTGTCCTCCTCTTCCTCCTCCTCCTCTGCCGCCTCCTCCTTGGACGCCGACGAGG ACGGCCCCATGCCCTCCCGCAACCGCCCGCCCATCAAGACCTACGAGGCCCGGAGCCGCATCGGGCTCAAGCTCAAGATCAAGCAGGAAG CCGGGCTCAGCAAGGTCGTGCACAACACGGCCCTGGACCCCGTGCACCAGCCCCCGCCACCCCCCGCTACCCTCAAGGTGGCCGAGCCCC CGCCACGGCCGCCACCACCACCGCCGCCCACGGGCCAGATGAACGGCACGGTGGACCACCCGCCGCCTGCCGCCCCCGAGCGCAAGCCCC TGGGCACCGCCCCGCACTGCCCGCGCCTGCCACTGCGCAAGACCTACCGCGAGAACGTGGGGGGCCCTGGCGCGCCGGAGGGGACGCCCG CAGGCAGGGCACGGGGAGGCAGCCCGGCGCCGCTGCCCGCCAAAGTGGACGAGGCCACCAGCGGGCTCATCCGCGAGCTGGCGGCCGTGG AGGACGAGCTGTACCAGCGTATGCTGAAGGGCCCCCCGCCAGAGCCCGCAGCCAGCGCCGCCCAAGGCACCGGGGACCCCGACTGGGAGG CGCCCGGGCTGCCCCCTGCCAAGCGGCGCAAGTCCGAGTCGCCCGACGTGGACCAGGCCAGCTTCTCCAGCGACAGCCCGCAGGATGACA CGCTCACCGAGCACCTGCAGAGCGCCATCGACAGCATCCTGAACCTGCAGCAGGCCCCCGGCCGGACGCCCGCGCCCTCGTACCCCCACG CTGCCTCGGCCGGCACCCCCGCATCCCCGCCGCCCCTGCACAGGCCCGAGGCCTACCCACCCTCCAGTCACAACGGTGGCCTCGGCGCCA GGACGTTGACCAGATAACACCGGGCCGCCTCCCCTTCCCCGTCCCCTCCTCCCGAAGACGCCGGGACAGTCGGGTGTCCGCCCTCAGCCT CCTGGGGACTCGAGCCGGGGATCCCCTGACGGTTTTTCTTGCCTAAGTTATTTGAGTCACAAAGGCCTCCTTCCCTGCCGCCTGCTTCAG CTGGGTTGCTGGGGGGTGGGCGTGGATTTAGGGAGGGGGCTGTGATGTAAAACGTCTCCCCTGCCAAAGGAGGGGCAAAGTGCTGTGTCA GTTCCTGTTTCTTCCCATTTCCTGGCACACTCTGCCCCTCTGTCCGGGGGACACGCGCATGTGTTTGCCAGGGATGGGGCCACCGGGTTG ATGCCAACGCTCCGGGTGCCTGTCTTGTCTGTGTGGCTTCTCAGATGGTGGAGGGTGCTGGGAGCTGGCAGGGTCCTTCCAGACAGTCTC AGCCTCTCCCCGCCGCCCCCAACAGGCTGTCAAACAAAACCGGAGAGGGGGTGGGGGAGCCAGCCTCCCAGCGTGCTGTGCCCGCAGGCA CCCGTGTGACATCCGCACGTCCAGCTCCGTGACCTGTGTGTGTGTGTGTGTGCACAAGTGAGTGAGAGATTTCGAACGCCCACCCCTCGA CTTTGAAATCTGAGCAAAACAAGAAACTGGGGTCTTCCTCTCCCCCGAACCTCTCCCCAGCTAGTCTTCCCTCTGTTCTTCCTGCCTCCA GCCGCCCGCGCCAGATTTTGAAATCTCGGAGACAAAACTAGTACTGTAAGATAAATTTTTTTGTACTGTATTTATTGTGTATAACGATTT |
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FusionGenePPI for BCL7A_GLTSCR1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| BCL7A | RELB, SMARCA2, SMARCA4, WHSC1L1, CUL3, CBX5, ALAS1, DPF3, DPF2, SS18, SMARCD1, ARID1A, ARID1B, SMARCB1, SMARCD2, SMARCD3, SMARCC1, SMARCC2, MAPK8, POTEJ, SPIRE1, PHACTR4, SPIRE2, PHACTR2, BRD9, MKL2, GLTSCR1, GLTSCR1L, MKL1, DPF1, BRD7, PBRM1, SCIN, CAP2, ARID2, ACTR8, GSN, INO80, PHF10, WDR54, INO80C, CAP1, INO80E, ACTL6B, BCL7C, KLHL23, SMARCE1, TWF2, EMC8, MYO1B, ACTBL2, ACTL6A | GLTSCR1 | NFYC, BRD4, SS18, SMARCD1, EWSR1, DYNC1H1, NEIL3, BCL7C, BCL7A, SPATA1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for BCL7A_GLTSCR1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for BCL7A_GLTSCR1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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