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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionGeneSequence

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Fusion gene ID: 40009

FusionGeneSummary for TTC7B_SLC35F4

check button Fusion gene summary
Fusion gene informationFusion gene name: TTC7B_SLC35F4
Fusion gene ID: 40009
HgeneTgene
Gene symbol

TTC7B

SLC35F4

Gene ID

145567

341880

Gene nametetratricopeptide repeat domain 7Bsolute carrier family 35 member F4
SynonymsTTC7L1|c14_5685C14orf36|c14_5373
Cytomap

14q32.11

14q22.3-q23.1

Type of geneprotein-codingprotein-coding
Descriptiontetratricopeptide repeat protein 7BTPR repeat protein 7-like-1TPR repeat protein 7Btetratricopeptide repeat domain 7 like 1tetratricopeptide repeat protein 7-like-1solute carrier family 35 member F4
Modification date2018052320180403
UniProtAcc

Q86TV6

A4IF30

Ensembl transtripts involved in fusion geneENST00000357056, ENST00000328459, 
ENST00000554654, 		ENST00000556826, 
ENST00000557430, ENST00000339762, 
ENST00000554729, 
Fusion gene scores* DoF score9 X 9 X 7=5672 X 2 X 2=8
# samples 102
** MAII scorelog2(10/567*10)=-2.5033487351675
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: TTC7B [Title/Abstract] AND SLC35F4 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTTC7B

GO:0046854

phosphatidylinositol phosphorylation

23229899|26571211

HgeneTTC7B

GO:0072659

protein localization to plasma membrane

23229899|26571211


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVSARCTCGA-IF-A3RQ-01ATTC7Bchr14

91196419

-SLC35F4chr14

58048151

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000357056ENST00000556826TTC7Bchr14

91196419

-SLC35F4chr14

58048151

-
5CDS-intronENST00000357056ENST00000557430TTC7Bchr14

91196419

-SLC35F4chr14

58048151

-
5CDS-intronENST00000357056ENST00000339762TTC7Bchr14

91196419

-SLC35F4chr14

58048151

-
5CDS-intronENST00000357056ENST00000554729TTC7Bchr14

91196419

-SLC35F4chr14

58048151

-
In-frameENST00000328459ENST00000556826TTC7Bchr14

91196419

-SLC35F4chr14

58048151

-
5CDS-intronENST00000328459ENST00000557430TTC7Bchr14

91196419

-SLC35F4chr14

58048151

-
5CDS-intronENST00000328459ENST00000339762TTC7Bchr14

91196419

-SLC35F4chr14

58048151

-
5CDS-intronENST00000328459ENST00000554729TTC7Bchr14

91196419

-SLC35F4chr14

58048151

-
intron-3CDSENST00000554654ENST00000556826TTC7Bchr14

91196419

-SLC35F4chr14

58048151

-
intron-intronENST00000554654ENST00000557430TTC7Bchr14

91196419

-SLC35F4chr14

58048151

-
intron-intronENST00000554654ENST00000339762TTC7Bchr14

91196419

-SLC35F4chr14

58048151

-
intron-intronENST00000554654ENST00000554729TTC7Bchr14

91196419

-SLC35F4chr14

58048151

-

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FusionProtFeatures for TTC7B_SLC35F4


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
TTC7B

Q86TV6

SLC35F4

A4IF30

Component of a complex required to localizephosphatidylinositol 4-kinase (PI4K) to the plasma membrane. Thecomplex acts as a regulator of phosphatidylinositol 4-phosphate(PtdIns(4)P) synthesis. In the complex, plays a central role inbridging PI4KA to EFR3B and FAM126A, via direct interactions(PubMed:26571211). {ECO:0000269|PubMed:23229899,ECO:0000269|PubMed:26571211}. Putative solute transporter. {ECO:0000305}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000328459-52097_131232844RepeatNote=TPR 1
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000357056-52197_131232861RepeatNote=TPR 1
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000339762-28261_321231522DomainNote=EamA
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000554729-28261_32172363DomainNote=EamA
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000339762-28248_266231522TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000339762-28277_297231522TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000339762-28301_321231522TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000339762-28330_350231522TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000339762-28365_385231522TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000339762-28395_417231522TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000339762-28419_441231522TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000339762-28450_470231522TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000554729-28160_18072363TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000554729-28192_21272363TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000554729-28248_26672363TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000554729-28277_29772363TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000554729-28301_32172363TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000554729-28330_35072363TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000554729-28365_38572363TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000554729-28395_41772363TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000554729-28419_44172363TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000554729-28450_47072363TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000328459-520329_333232844Compositional biasNote=Poly-Leu
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000357056-521329_333232861Compositional biasNote=Poly-Leu
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000328459-520219_252232844RepeatNote=TPR 2
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000328459-520363_396232844RepeatNote=TPR 3
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000328459-520397_430232844RepeatNote=TPR 4
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000328459-520479_514232844RepeatNote=TPR 5
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000328459-520516_548232844RepeatNote=TPR 6
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000328459-520549_582232844RepeatNote=TPR 7
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000328459-520696_729232844RepeatNote=TPR 8
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000328459-520730_763232844RepeatNote=TPR 9
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000328459-520765_797232844RepeatNote=TPR 10
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000328459-520798_831232844RepeatNote=TPR 11
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000357056-521219_252232861RepeatNote=TPR 2
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000357056-521363_396232861RepeatNote=TPR 3
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000357056-521397_430232861RepeatNote=TPR 4
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000357056-521479_514232861RepeatNote=TPR 5
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000357056-521516_548232861RepeatNote=TPR 6
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000357056-521549_582232861RepeatNote=TPR 7
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000357056-521696_729232861RepeatNote=TPR 8
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000357056-521730_763232861RepeatNote=TPR 9
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000357056-521765_797232861RepeatNote=TPR 10
HgeneTTC7Bchr14:91196419chr14:58048151ENST00000357056-521798_831232861RepeatNote=TPR 11
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000339762-28160_180231522TransmembraneHelical
TgeneSLC35F4chr14:91196419chr14:58048151ENST00000339762-28192_212231522TransmembraneHelical


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FusionGeneSequence for TTC7B_SLC35F4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_TTC7B_ENST00000357056_chr14_91196419_-_SLC35F4_ENST00000556826_chr14_58048151_-_523aa
MATKKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQYLKEHPLRQGASPRGPKPQLTEVRKHLTAALDRGN
LKSEFLQESNLIMAKLNYVEGDYKEALNIYARVGLDDLPLTAVPPYRLRVIAEAYATKGLCLEKLPISSSTSNLHVDREQDVITCYEKAG
DIALLYLQEIERVILSNIQNRSPKPGPAPHDQELGFFLETGLQRAHVLYFKNGECSRIFGEDGLTLKLFLKRTAPFSILWTLTNYLYLLA
LKKLTATDVSALFCCNKAFVFLLSWIVLKDRFMGVRIVAAIMAITGIVMMAYADNFHADSIIGVAFAVGSASTSALYKVLFKMFLGSANF
GEAAHFVSTLGFFNLIFISFTPVILYFTKVEHWSSFAALPWGCLCGMAGLWLAFNILVNVGVVLTYPILISIGTVLSVPGNAAVDLLKQE

>In-frame_TTC7B_ENST00000328459_chr14_91196419_-_SLC35F4_ENST00000556826_chr14_58048151_-_523aa
MATKKAGSRLETEIERCRSECQWERIPELVKQLSAKLIANDDMAELLLGESKLEQYLKEHPLRQGASPRGPKPQLTEVRKHLTAALDRGN
LKSEFLQESNLIMAKLNYVEGDYKEALNIYARVGLDDLPLTAVPPYRLRVIAEAYATKGLCLEKLPISSSTSNLHVDREQDVITCYEKAG
DIALLYLQEIERVILSNIQNRSPKPGPAPHDQELGFFLETGLQRAHVLYFKNGECSRIFGEDGLTLKLFLKRTAPFSILWTLTNYLYLLA
LKKLTATDVSALFCCNKAFVFLLSWIVLKDRFMGVRIVAAIMAITGIVMMAYADNFHADSIIGVAFAVGSASTSALYKVLFKMFLGSANF
GEAAHFVSTLGFFNLIFISFTPVILYFTKVEHWSSFAALPWGCLCGMAGLWLAFNILVNVGVVLTYPILISIGTVLSVPGNAAVDLLKQE


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_TTC7B_ENST00000357056_chr14_91196419_-_SLC35F4_ENST00000556826_chr14_58048151_-_1569nt
ATGGCGACCAAGAAGGCAGGCTCGCGGCTGGAGACGGAGATCGAGCGCTGCCGCTCCGAGTGCCAGTGGGAGCGGATCCCTGAGCTCGTC
AAGCAGCTGTCGGCCAAGCTCATCGCCAACGATGACATGGCAGAGCTTCTCCTCGGGGAGTCGAAGCTGGAGCAGTACCTGAAGGAACAC
CCCCTGAGGCAGGGGGCCAGTCCCCGAGGCCCCAAGCCCCAGCTGACTGAGGTCCGCAAGCATCTGACCGCCGCCCTGGACCGAGGGAAC
CTTAAGTCAGAATTCCTACAAGAATCCAATCTGATCATGGCCAAGTTGAATTATGTGGAAGGTGATTATAAAGAAGCTCTGAACATTTAC
GCCCGGGTGGGCCTGGACGATCTGCCACTGACAGCTGTCCCGCCCTACAGGCTGCGGGTGATCGCAGAAGCCTACGCTACCAAAGGACTT
TGTTTGGAGAAGCTGCCTATTTCTTCTTCTACCAGTAATCTCCATGTGGACCGGGAACAGGATGTCATCACCTGTTATGAGAAAGCAGGG
GACATCGCACTCCTGTATCTCCAAGAGATAGAAAGGGTAATACTTTCTAATATTCAAAACAGAAGCCCTAAGCCTGGCCCTGCTCCCCAC
GATCAAGAACTAGGTTTTTTCCTAGAAACAGGACTTCAGAGAGCCCATGTCCTCTATTTCAAAAATGGGGAATGCAGTCGGATTTTTGGT
GAAGATGGTCTGACGCTGAAACTCTTTCTTAAAAGAACTGCTCCCTTTTCTATTCTATGGACTTTGACTAATTACCTTTATTTACTGGCT
TTAAAGAAGCTGACGGCCACGGATGTCTCCGCTCTGTTCTGTTGTAACAAAGCCTTTGTCTTCTTGCTGTCATGGATTGTGCTGAAAGAC
AGGTTCATGGGAGTGAGGATAGTTGCTGCAATAATGGCAATTACCGGCATTGTCATGATGGCATATGCAGATAATTTCCACGCTGATTCC
ATCATAGGAGTGGCATTTGCGGTGGGCTCAGCCTCTACATCTGCATTATATAAGGTCTTGTTTAAAATGTTTCTTGGAAGTGCCAACTTT
GGGGAAGCTGCACACTTTGTCTCCACCTTGGGTTTCTTCAATTTGATCTTCATCTCCTTCACCCCAGTCATCTTGTATTTCACCAAGGTG
GAGCACTGGTCCTCTTTTGCTGCTCTGCCATGGGGCTGTCTCTGTGGGATGGCAGGGCTGTGGCTGGCCTTCAACATCCTGGTGAATGTT
GGGGTGGTGCTGACATACCCAATCCTAATCTCCATTGGGACAGTGCTCAGCGTTCCTGGAAATGCAGCTGTGGATCTCCTAAAGCAGGAG
GTGATATTCAATGTTGTCCGCCTGGCTGCTACCATCATCATCTGCATTGGGTTTCTGCTGATGCTGTTGCCTGAGGAATGGGATGAAATC
ACCCTGAGGTTCATCAACAGCCTGAAGGAAAAGAAGAGTGAGGAGCATGTGGATGATGTGACTGATCCCAGCATACACCTGCGGGGCAGA

>In-frame_TTC7B_ENST00000328459_chr14_91196419_-_SLC35F4_ENST00000556826_chr14_58048151_-_1569nt
ATGGCGACCAAGAAGGCAGGCTCGCGGCTGGAGACGGAGATCGAGCGCTGCCGCTCCGAGTGCCAGTGGGAGCGGATCCCTGAGCTCGTC
AAGCAGCTGTCGGCCAAGCTCATCGCCAACGATGACATGGCAGAGCTTCTCCTCGGGGAGTCGAAGCTGGAGCAGTACCTGAAGGAACAC
CCCCTGAGGCAGGGGGCCAGTCCCCGAGGCCCCAAGCCCCAGCTGACTGAGGTCCGCAAGCATCTGACCGCCGCCCTGGACCGAGGGAAC
CTTAAGTCAGAATTCCTACAAGAATCCAATCTGATCATGGCCAAGTTGAATTATGTGGAAGGTGATTATAAAGAAGCTCTGAACATTTAC
GCCCGGGTGGGCCTGGACGATCTGCCACTGACAGCTGTCCCGCCCTACAGGCTGCGGGTGATCGCAGAAGCCTACGCTACCAAAGGACTT
TGTTTGGAGAAGCTGCCTATTTCTTCTTCTACCAGTAATCTCCATGTGGACCGGGAACAGGATGTCATCACCTGTTATGAGAAAGCAGGG
GACATCGCACTCCTGTATCTCCAAGAGATAGAAAGGGTAATACTTTCTAATATTCAAAACAGAAGCCCTAAGCCTGGCCCTGCTCCCCAC
GATCAAGAACTAGGTTTTTTCCTAGAAACAGGACTTCAGAGAGCCCATGTCCTCTATTTCAAAAATGGGGAATGCAGTCGGATTTTTGGT
GAAGATGGTCTGACGCTGAAACTCTTTCTTAAAAGAACTGCTCCCTTTTCTATTCTATGGACTTTGACTAATTACCTTTATTTACTGGCT
TTAAAGAAGCTGACGGCCACGGATGTCTCCGCTCTGTTCTGTTGTAACAAAGCCTTTGTCTTCTTGCTGTCATGGATTGTGCTGAAAGAC
AGGTTCATGGGAGTGAGGATAGTTGCTGCAATAATGGCAATTACCGGCATTGTCATGATGGCATATGCAGATAATTTCCACGCTGATTCC
ATCATAGGAGTGGCATTTGCGGTGGGCTCAGCCTCTACATCTGCATTATATAAGGTCTTGTTTAAAATGTTTCTTGGAAGTGCCAACTTT
GGGGAAGCTGCACACTTTGTCTCCACCTTGGGTTTCTTCAATTTGATCTTCATCTCCTTCACCCCAGTCATCTTGTATTTCACCAAGGTG
GAGCACTGGTCCTCTTTTGCTGCTCTGCCATGGGGCTGTCTCTGTGGGATGGCAGGGCTGTGGCTGGCCTTCAACATCCTGGTGAATGTT
GGGGTGGTGCTGACATACCCAATCCTAATCTCCATTGGGACAGTGCTCAGCGTTCCTGGAAATGCAGCTGTGGATCTCCTAAAGCAGGAG
GTGATATTCAATGTTGTCCGCCTGGCTGCTACCATCATCATCTGCATTGGGTTTCTGCTGATGCTGTTGCCTGAGGAATGGGATGAAATC
ACCCTGAGGTTCATCAACAGCCTGAAGGAAAAGAAGAGTGAGGAGCATGTGGATGATGTGACTGATCCCAGCATACACCTGCGGGGCAGA


* Fusion transcript sequences (Full-length transcript).
>In-frame_TTC7B_ENST00000357056_chr14_91196419_-_SLC35F4_ENST00000556826_chr14_58048151_-_1904nt
GTTACGCCGCGGAGCCGGGAGCCGGAGCCCGAGCCCGCGGCGGCGGCGGGAGGCGGCGAGGGGGCGCCGCGGCGGCGGCGGTGGGGCCTG
CGGGGCGGGCGGCCGGGCCCGGCCAGGCCGCGATGGCGACCAAGAAGGCAGGCTCGCGGCTGGAGACGGAGATCGAGCGCTGCCGCTCCG
AGTGCCAGTGGGAGCGGATCCCTGAGCTCGTCAAGCAGCTGTCGGCCAAGCTCATCGCCAACGATGACATGGCAGAGCTTCTCCTCGGGG
AGTCGAAGCTGGAGCAGTACCTGAAGGAACACCCCCTGAGGCAGGGGGCCAGTCCCCGAGGCCCCAAGCCCCAGCTGACTGAGGTCCGCA
AGCATCTGACCGCCGCCCTGGACCGAGGGAACCTTAAGTCAGAATTCCTACAAGAATCCAATCTGATCATGGCCAAGTTGAATTATGTGG
AAGGTGATTATAAAGAAGCTCTGAACATTTACGCCCGGGTGGGCCTGGACGATCTGCCACTGACAGCTGTCCCGCCCTACAGGCTGCGGG
TGATCGCAGAAGCCTACGCTACCAAAGGACTTTGTTTGGAGAAGCTGCCTATTTCTTCTTCTACCAGTAATCTCCATGTGGACCGGGAAC
AGGATGTCATCACCTGTTATGAGAAAGCAGGGGACATCGCACTCCTGTATCTCCAAGAGATAGAAAGGGTAATACTTTCTAATATTCAAA
ACAGAAGCCCTAAGCCTGGCCCTGCTCCCCACGATCAAGAACTAGGTTTTTTCCTAGAAACAGGACTTCAGAGAGCCCATGTCCTCTATT
TCAAAAATGGGGAATGCAGTCGGATTTTTGGTGAAGATGGTCTGACGCTGAAACTCTTTCTTAAAAGAACTGCTCCCTTTTCTATTCTAT
GGACTTTGACTAATTACCTTTATTTACTGGCTTTAAAGAAGCTGACGGCCACGGATGTCTCCGCTCTGTTCTGTTGTAACAAAGCCTTTG
TCTTCTTGCTGTCATGGATTGTGCTGAAAGACAGGTTCATGGGAGTGAGGATAGTTGCTGCAATAATGGCAATTACCGGCATTGTCATGA
TGGCATATGCAGATAATTTCCACGCTGATTCCATCATAGGAGTGGCATTTGCGGTGGGCTCAGCCTCTACATCTGCATTATATAAGGTCT
TGTTTAAAATGTTTCTTGGAAGTGCCAACTTTGGGGAAGCTGCACACTTTGTCTCCACCTTGGGTTTCTTCAATTTGATCTTCATCTCCT
TCACCCCAGTCATCTTGTATTTCACCAAGGTGGAGCACTGGTCCTCTTTTGCTGCTCTGCCATGGGGCTGTCTCTGTGGGATGGCAGGGC
TGTGGCTGGCCTTCAACATCCTGGTGAATGTTGGGGTGGTGCTGACATACCCAATCCTAATCTCCATTGGGACAGTGCTCAGCGTTCCTG
GAAATGCAGCTGTGGATCTCCTAAAGCAGGAGGTGATATTCAATGTTGTCCGCCTGGCTGCTACCATCATCATCTGCATTGGGTTTCTGC
TGATGCTGTTGCCTGAGGAATGGGATGAAATCACCCTGAGGTTCATCAACAGCCTGAAGGAAAAGAAGAGTGAGGAGCATGTGGATGATG
TGACTGATCCCAGCATACACCTGCGGGGCAGAGGCAGAGCCAATGGGACAGTGTCTATACCACTGGCTTAGAGAGGGACATATTTTGAAT
GCACGTGTATGTATATTCTGTGAATATAACAAAATTTTCTCACTACCTGTACACTCAAACGACAGTATTAACTCTGAATTTGGATAAATC
ATATGTGAAATAATGCCAACAATAAAAGTTTACATTTATATGCTTATCAAGGAATTGGTGTAAATAATCATAATGGATTTTTTTATTAAA

>In-frame_TTC7B_ENST00000328459_chr14_91196419_-_SLC35F4_ENST00000556826_chr14_58048151_-_1904nt
GTTACGCCGCGGAGCCGGGAGCCGGAGCCCGAGCCCGCGGCGGCGGCGGGAGGCGGCGAGGGGGCGCCGCGGCGGCGGCGGTGGGGCCTG
CGGGGCGGGCGGCCGGGCCCGGCCAGGCCGCGATGGCGACCAAGAAGGCAGGCTCGCGGCTGGAGACGGAGATCGAGCGCTGCCGCTCCG
AGTGCCAGTGGGAGCGGATCCCTGAGCTCGTCAAGCAGCTGTCGGCCAAGCTCATCGCCAACGATGACATGGCAGAGCTTCTCCTCGGGG
AGTCGAAGCTGGAGCAGTACCTGAAGGAACACCCCCTGAGGCAGGGGGCCAGTCCCCGAGGCCCCAAGCCCCAGCTGACTGAGGTCCGCA
AGCATCTGACCGCCGCCCTGGACCGAGGGAACCTTAAGTCAGAATTCCTACAAGAATCCAATCTGATCATGGCCAAGTTGAATTATGTGG
AAGGTGATTATAAAGAAGCTCTGAACATTTACGCCCGGGTGGGCCTGGACGATCTGCCACTGACAGCTGTCCCGCCCTACAGGCTGCGGG
TGATCGCAGAAGCCTACGCTACCAAAGGACTTTGTTTGGAGAAGCTGCCTATTTCTTCTTCTACCAGTAATCTCCATGTGGACCGGGAAC
AGGATGTCATCACCTGTTATGAGAAAGCAGGGGACATCGCACTCCTGTATCTCCAAGAGATAGAAAGGGTAATACTTTCTAATATTCAAA
ACAGAAGCCCTAAGCCTGGCCCTGCTCCCCACGATCAAGAACTAGGTTTTTTCCTAGAAACAGGACTTCAGAGAGCCCATGTCCTCTATT
TCAAAAATGGGGAATGCAGTCGGATTTTTGGTGAAGATGGTCTGACGCTGAAACTCTTTCTTAAAAGAACTGCTCCCTTTTCTATTCTAT
GGACTTTGACTAATTACCTTTATTTACTGGCTTTAAAGAAGCTGACGGCCACGGATGTCTCCGCTCTGTTCTGTTGTAACAAAGCCTTTG
TCTTCTTGCTGTCATGGATTGTGCTGAAAGACAGGTTCATGGGAGTGAGGATAGTTGCTGCAATAATGGCAATTACCGGCATTGTCATGA
TGGCATATGCAGATAATTTCCACGCTGATTCCATCATAGGAGTGGCATTTGCGGTGGGCTCAGCCTCTACATCTGCATTATATAAGGTCT
TGTTTAAAATGTTTCTTGGAAGTGCCAACTTTGGGGAAGCTGCACACTTTGTCTCCACCTTGGGTTTCTTCAATTTGATCTTCATCTCCT
TCACCCCAGTCATCTTGTATTTCACCAAGGTGGAGCACTGGTCCTCTTTTGCTGCTCTGCCATGGGGCTGTCTCTGTGGGATGGCAGGGC
TGTGGCTGGCCTTCAACATCCTGGTGAATGTTGGGGTGGTGCTGACATACCCAATCCTAATCTCCATTGGGACAGTGCTCAGCGTTCCTG
GAAATGCAGCTGTGGATCTCCTAAAGCAGGAGGTGATATTCAATGTTGTCCGCCTGGCTGCTACCATCATCATCTGCATTGGGTTTCTGC
TGATGCTGTTGCCTGAGGAATGGGATGAAATCACCCTGAGGTTCATCAACAGCCTGAAGGAAAAGAAGAGTGAGGAGCATGTGGATGATG
TGACTGATCCCAGCATACACCTGCGGGGCAGAGGCAGAGCCAATGGGACAGTGTCTATACCACTGGCTTAGAGAGGGACATATTTTGAAT
GCACGTGTATGTATATTCTGTGAATATAACAAAATTTTCTCACTACCTGTACACTCAAACGACAGTATTAACTCTGAATTTGGATAAATC
ATATGTGAAATAATGCCAACAATAAAAGTTTACATTTATATGCTTATCAAGGAATTGGTGTAAATAATCATAATGGATTTTTTTATTAAA


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FusionGenePPI for TTC7B_SLC35F4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
TTC7BCUL3, CTDSPL, RGS20SLC35F4


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for TTC7B_SLC35F4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for TTC7B_SLC35F4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource