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Fusion gene ID: 39586 |
FusionGeneSummary for TRIO_IQUB |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TRIO_IQUB | Fusion gene ID: 39586 | Hgene | Tgene | Gene symbol | TRIO | IQUB | Gene ID | 7204 | 154865 |
| Gene name | trio Rho guanine nucleotide exchange factor | IQ motif and ubiquitin domain containing | |
| Synonyms | ARHGEF23|MEBAS|MRD44|tgat | - | |
| Cytomap | 5p15.2 | 7q31.32 | |
| Type of gene | protein-coding | protein-coding | |
| Description | triple functional domain proteinPTPRF-interacting proteintriple functional domain (PTPRF interacting) | IQ and ubiquitin-like domain-containing protein | |
| Modification date | 20180527 | 20180519 | |
| UniProtAcc | O75962 | Q8NA54 | |
| Ensembl transtripts involved in fusion gene | ENST00000344204, ENST00000537187, ENST00000509967, ENST00000515710, ENST00000344135, | ENST00000466202, ENST00000324698, ENST00000434450, ENST00000488987, | |
| Fusion gene scores | * DoF score | 26 X 18 X 10=4680 | 1 X 1 X 1=1 |
| # samples | 27 | 1 | |
| ** MAII score | log2(27/4680*10)=-4.11547721741994 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: TRIO [Title/Abstract] AND IQUB [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-CH-5741-01A | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000344204 | ENST00000466202 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| In-frame | ENST00000344204 | ENST00000324698 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| 5CDS-intron | ENST00000344204 | ENST00000434450 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| 5CDS-intron | ENST00000344204 | ENST00000488987 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| In-frame | ENST00000537187 | ENST00000466202 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| In-frame | ENST00000537187 | ENST00000324698 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| 5CDS-intron | ENST00000537187 | ENST00000434450 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| 5CDS-intron | ENST00000537187 | ENST00000488987 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| In-frame | ENST00000509967 | ENST00000466202 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| In-frame | ENST00000509967 | ENST00000324698 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| 5CDS-intron | ENST00000509967 | ENST00000434450 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| 5CDS-intron | ENST00000509967 | ENST00000488987 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| intron-3CDS | ENST00000515710 | ENST00000466202 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| intron-3CDS | ENST00000515710 | ENST00000324698 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| intron-intron | ENST00000515710 | ENST00000434450 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| intron-intron | ENST00000515710 | ENST00000488987 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| intron-3CDS | ENST00000344135 | ENST00000466202 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| intron-3CDS | ENST00000344135 | ENST00000324698 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| intron-intron | ENST00000344135 | ENST00000434450 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
| intron-intron | ENST00000344135 | ENST00000488987 | TRIO | chr5 | 14304701 | + | IQUB | chr7 | 123097620 | - |
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FusionProtFeatures for TRIO_IQUB |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TRIO | IQUB |
| Guanine nucleotide exchange factor (GEF) for RHOA andRAC1 GTPases (PubMed:8643598, PubMed:27418539). Involved incoordinating actin remodeling, which is necessary for cellmigration and growth (PubMed:10341202). In developing hippocampalneurons, limits dendrite formation, without affecting theestablishment of axon polarity. Once dendrites are formed,involved in the control of synaptic function by regulating theendocytosis of AMPA-selective glutamate receptors (AMPARs) at CA1excitatory synapses (By similarity). May act as a regulator ofadipogenesis (By similarity). {ECO:0000250|UniProtKB:F1M0Z1,ECO:0000269|PubMed:10341202, ECO:0000269|PubMed:27418539,ECO:0000269|PubMed:8643598}. | May play roles in cilia formation and/or maintenance.{ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 65_210 | 500 | 3098 | Domain | CRAL-TRIO |
| Hgene | TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 65_210 | 500 | 2922 | Domain | CRAL-TRIO |
| Hgene | TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 311_418 | 500 | 3098 | Repeat | Note=Spectrin 1 |
| Hgene | TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 311_418 | 500 | 2922 | Repeat | Note=Spectrin 1 |
| Tgene | >IQUB | chr5:14304701 | chr7:123097620 | ENST00000434450 | - | 0 | 11 | 131_207 | -59 | 597 | Domain | Ubiquitin-like |
| Tgene | >IQUB | chr5:14304701 | chr7:123097620 | ENST00000434450 | - | 0 | 11 | 338_367 | -59 | 597 | Domain | Note=IQ |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 1845_1850 | -165 | 597 | Compositional bias | Note=Poly-Ser |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 2292_2312 | -165 | 597 | Compositional bias | Note=Poly-Gly |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 2545_2551 | -165 | 597 | Compositional bias | Note=Poly-Ser |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 715_718 | -165 | 597 | Compositional bias | Note=Poly-Gln |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 1845_1850 | 500 | 3098 | Compositional bias | Note=Poly-Ser |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 2292_2312 | 500 | 3098 | Compositional bias | Note=Poly-Gly |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 2545_2551 | 500 | 3098 | Compositional bias | Note=Poly-Ser |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 715_718 | 500 | 3098 | Compositional bias | Note=Poly-Gln |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 1845_1850 | 500 | 2922 | Compositional bias | Note=Poly-Ser |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 2292_2312 | 500 | 2922 | Compositional bias | Note=Poly-Gly |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 2545_2551 | 500 | 2922 | Compositional bias | Note=Poly-Ser |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 715_718 | 500 | 2922 | Compositional bias | Note=Poly-Gln |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 1292_1467 | -165 | 597 | Domain | DH 1 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 1480_1591 | -165 | 597 | Domain | PH 1 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 1656_1721 | -165 | 597 | Domain | SH3 1 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 1969_2145 | -165 | 597 | Domain | DH 2 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 2157_2271 | -165 | 597 | Domain | PH 2 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 2551_2616 | -165 | 597 | Domain | SH3 2 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 2685_2775 | -165 | 597 | Domain | Note=Ig-like C2-type |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 2796_3052 | -165 | 597 | Domain | Protein kinase |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 65_210 | -165 | 597 | Domain | CRAL-TRIO |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 1292_1467 | 500 | 3098 | Domain | DH 1 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 1480_1591 | 500 | 3098 | Domain | PH 1 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 1656_1721 | 500 | 3098 | Domain | SH3 1 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 1969_2145 | 500 | 3098 | Domain | DH 2 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 2157_2271 | 500 | 3098 | Domain | PH 2 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 2551_2616 | 500 | 3098 | Domain | SH3 2 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 2685_2775 | 500 | 3098 | Domain | Note=Ig-like C2-type |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 2796_3052 | 500 | 3098 | Domain | Protein kinase |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 1292_1467 | 500 | 2922 | Domain | DH 1 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 1480_1591 | 500 | 2922 | Domain | PH 1 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 1656_1721 | 500 | 2922 | Domain | SH3 1 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 1969_2145 | 500 | 2922 | Domain | DH 2 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 2157_2271 | 500 | 2922 | Domain | PH 2 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 2551_2616 | 500 | 2922 | Domain | SH3 2 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 2685_2775 | 500 | 2922 | Domain | Note=Ig-like C2-type |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 2796_3052 | 500 | 2922 | Domain | Protein kinase |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 2802_2810 | -165 | 597 | Nucleotide binding | ATP |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 2802_2810 | 500 | 3098 | Nucleotide binding | ATP |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 2802_2810 | 500 | 2922 | Nucleotide binding | ATP |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 1109_1216 | -165 | 597 | Repeat | Note=Spectrin 4 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 311_418 | -165 | 597 | Repeat | Note=Spectrin 1 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 538_644 | -165 | 597 | Repeat | Note=Spectrin 2 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344135 | + | 1 | 10 | 878_984 | -165 | 597 | Repeat | Note=Spectrin 3 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 1109_1216 | 500 | 3098 | Repeat | Note=Spectrin 4 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 538_644 | 500 | 3098 | Repeat | Note=Spectrin 2 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000344204 | + | 8 | 57 | 878_984 | 500 | 3098 | Repeat | Note=Spectrin 3 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 1109_1216 | 500 | 2922 | Repeat | Note=Spectrin 4 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 538_644 | 500 | 2922 | Repeat | Note=Spectrin 2 |
| Hgene | >TRIO | chr5:14304701 | chr7:123097620 | ENST00000537187 | + | 8 | 58 | 878_984 | 500 | 2922 | Repeat | Note=Spectrin 3 |
| Tgene | IQUB | chr5:14304701 | chr7:123097620 | ENST00000324698 | - | 10 | 13 | 131_207 | 669 | 792 | Domain | Ubiquitin-like |
| Tgene | IQUB | chr5:14304701 | chr7:123097620 | ENST00000324698 | - | 10 | 13 | 338_367 | 669 | 792 | Domain | Note=IQ |
| Tgene | IQUB | chr5:14304701 | chr7:123097620 | ENST00000466202 | - | 10 | 13 | 131_207 | 669 | 792 | Domain | Ubiquitin-like |
| Tgene | IQUB | chr5:14304701 | chr7:123097620 | ENST00000466202 | - | 10 | 13 | 338_367 | 669 | 792 | Domain | Note=IQ |
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FusionGeneSequence for TRIO_IQUB |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TRIO_ENST00000344204_chr5_14304701_+_IQUB_ENST00000466202_chr7_123097620_-_623aa MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEMKAMDVLPILKEKVAYLSGGRDKRGGPILTF PARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQLKKKVIKA PIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERSTLLDMSSIF HQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSELQDIQYLTENIWASQSVLSACDNLSDLVMVRWNKSLEWSP >In-frame_TRIO_ENST00000344204_chr5_14304701_+_IQUB_ENST00000324698_chr7_123097620_-_623aa MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEMKAMDVLPILKEKVAYLSGGRDKRGGPILTF PARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQLKKKVIKA PIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERSTLLDMSSIF HQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSELQDIQYLTENIWASQSVLSACDNLSDLVMVRWNKSLEWSP >In-frame_TRIO_ENST00000537187_chr5_14304701_+_IQUB_ENST00000466202_chr7_123097620_-_623aa MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEMKAMDVLPILKEKVAYLSGGRDKRGGPILTF PARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQLKKKVIKA PIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERSTLLDMSSIF HQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSELQDIQYLTENIWASQSVLSACDNLSDLVMVRWNKSLEWSP >In-frame_TRIO_ENST00000537187_chr5_14304701_+_IQUB_ENST00000324698_chr7_123097620_-_623aa MSGSSGGAAAPAASSGPAAAASAAGSGCGGGAGEGAEEAAKDLADIAAFFRSGFRKNDEMKAMDVLPILKEKVAYLSGGRDKRGGPILTF PARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIKPLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFE TNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATHMLSRLEELQDILAKKELPQDLEGARNMIEEHSQLKKKVIKA PIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNK GLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLVESGHYASQQIRQIASQLEQEWKAFAAALDERSTLLDMSSIF HQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYSELQDIQYLTENIWASQSVLSACDNLSDLVMVRWNKSLEWSP >In-frame_TRIO_ENST00000509967_chr5_14304701_+_IQUB_ENST00000466202_chr7_123097620_-_574aa MAEGFRKNDEMKAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIK PLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATH MLSRLEELQDILAKKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLH STRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLV ESGHYASQQIRQIASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYS ELQDIQYLTENIWASQSVLSACDNLSDLVMVRWNKSLEWSPWNCILLTKDEAAAHLKLTSIEEGYERSFIHKIKHKHILAKNYFSQVPVL >In-frame_TRIO_ENST00000509967_chr5_14304701_+_IQUB_ENST00000324698_chr7_123097620_-_574aa MAEGFRKNDEMKAMDVLPILKEKVAYLSGGRDKRGGPILTFPARSNHDRIRQEDLRRLISYLACIPSEEVCKRGFTVIVDMRGSKWDSIK PLLKILQESFPCCIHVALIIKPDNFWQKQRTNFGSSKFEFETNMVSLEGLTKVVDPSQLTPEFDGCLEYNHEEWIEIRVAFEDYISNATH MLSRLEELQDILAKKELPQDLEGARNMIEEHSQLKKKVIKAPIEDLDLEGQKLLQRIQSSESFPKKNSGSGNADLQNLLPKVSTMLDRLH STRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWITHNKGLFLNSYTEIGTSHPHAMELQTQHNHFAMNCMNVYVNINRIMSVANRLV ESGHYASQQIRQIASQLEQEWKAFAAALDERSTLLDMSSIFHQKAEKYMSNVDSWCKACGEVDLPSELQDLEDAIHHHQGIYEHITLAYS ELQDIQYLTENIWASQSVLSACDNLSDLVMVRWNKSLEWSPWNCILLTKDEAAAHLKLTSIEEGYERSFIHKIKHKHILAKNYFSQVPVL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TRIO_ENST00000344204_chr5_14304701_+_IQUB_ENST00000466202_chr7_123097620_-_1869nt ATGAGCGGCAGCAGCGGCGGAGCCGCCGCCCCCGCCGCGTCCTCCGGCCCCGCCGCGGCGGCCAGCGCGGCTGGCTCGGGCTGCGGGGGC GGTGCCGGCGAGGGGGCAGAGGAGGCGGCCAAGGACCTGGCCGACATCGCGGCCTTCTTCCGATCCGGGTTTCGAAAAAACGATGAAATG AAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGAGATAAACGTGGAGGTCCCATTTTAACGTTT CCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCCTGTATTCCCAGCGAGGAGGTCTGC AAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCCCTTCTGAAGATCCTGCAGGAGTCCTTCCCC TGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGGACTAATTTTGGCAGTTCTAAATTTGAATTTGAG ACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCTGAGTTTGATGGCTGCCTGGAATACAACCAC GAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCACATGCTGTCTCGGCTGGAGGAACTTCAGGACATC CTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACATTCTCAGCTGAAGAAGAAGGTGATTAAGGCC CCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTTCCCAAAAAGAACTCAGGCTCAGGC AATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCGACACGGCAGCATCTGCACCAGATGTGGCAT GTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATGTTTGACTGGATCACACACAACAAA GGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTTCAGACGCAGCACAATCACTTTGCCATGAAC TGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGCCACTATGCCTCGCAGCAGATCAGG CAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGGAGCACCTTGCTGGACATGTCCTCCATTTTC CACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGACCTTCCCTCAGAGCTGCAGGACCTA GAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAGCTACAAGACATTCAGTACCTGACAGAGAAC ATCTGGGCGTCCCAGTCAGTCCTCAGTGCTTGCGACAATCTCAGTGATCTGGTCATGGTCAGATGGAATAAATCCCTGGAGTGGTCCCCC TGGAACTGCATTCTTCTTACCAAAGATGAAGCAGCTGCTCATCTCAAGCTAACAAGTATTGAAGAGGGATATGAACGCTCATTTATTCAC AAGATCAAACACAAACATATCCTGGCTAAGAACTATTTTTCTCAGGTTCCAGTGCTGGCTTCATTTATACTTGATGATGGTGAAATTGAT >In-frame_TRIO_ENST00000344204_chr5_14304701_+_IQUB_ENST00000324698_chr7_123097620_-_1869nt ATGAGCGGCAGCAGCGGCGGAGCCGCCGCCCCCGCCGCGTCCTCCGGCCCCGCCGCGGCGGCCAGCGCGGCTGGCTCGGGCTGCGGGGGC GGTGCCGGCGAGGGGGCAGAGGAGGCGGCCAAGGACCTGGCCGACATCGCGGCCTTCTTCCGATCCGGGTTTCGAAAAAACGATGAAATG AAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGAGATAAACGTGGAGGTCCCATTTTAACGTTT CCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCCTGTATTCCCAGCGAGGAGGTCTGC AAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCCCTTCTGAAGATCCTGCAGGAGTCCTTCCCC TGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGGACTAATTTTGGCAGTTCTAAATTTGAATTTGAG ACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCTGAGTTTGATGGCTGCCTGGAATACAACCAC GAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCACATGCTGTCTCGGCTGGAGGAACTTCAGGACATC CTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACATTCTCAGCTGAAGAAGAAGGTGATTAAGGCC CCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTTCCCAAAAAGAACTCAGGCTCAGGC AATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCGACACGGCAGCATCTGCACCAGATGTGGCAT GTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATGTTTGACTGGATCACACACAACAAA GGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTTCAGACGCAGCACAATCACTTTGCCATGAAC TGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGCCACTATGCCTCGCAGCAGATCAGG CAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGGAGCACCTTGCTGGACATGTCCTCCATTTTC CACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGACCTTCCCTCAGAGCTGCAGGACCTA GAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAGCTACAAGACATTCAGTACCTGACAGAGAAC ATCTGGGCGTCCCAGTCAGTCCTCAGTGCTTGCGACAATCTCAGTGATCTGGTCATGGTCAGATGGAATAAATCCCTGGAGTGGTCCCCC TGGAACTGCATTCTTCTTACCAAAGATGAAGCAGCTGCTCATCTCAAGCTAACAAGTATTGAAGAGGGATATGAACGCTCATTTATTCAC AAGATCAAACACAAACATATCCTGGCTAAGAACTATTTTTCTCAGGTTCCAGTGCTGGCTTCATTTATACTTGATGATGGTGAAATTGAT >In-frame_TRIO_ENST00000537187_chr5_14304701_+_IQUB_ENST00000466202_chr7_123097620_-_1869nt ATGAGCGGCAGCAGCGGCGGAGCCGCCGCCCCCGCCGCGTCCTCCGGCCCCGCCGCGGCGGCCAGCGCGGCTGGCTCGGGCTGCGGGGGC GGTGCCGGCGAGGGGGCAGAGGAGGCGGCCAAGGACCTGGCCGACATCGCGGCCTTCTTCCGATCCGGGTTTCGAAAAAACGATGAAATG AAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGAGATAAACGTGGAGGTCCCATTTTAACGTTT CCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCCTGTATTCCCAGCGAGGAGGTCTGC AAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCCCTTCTGAAGATCCTGCAGGAGTCCTTCCCC TGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGGACTAATTTTGGCAGTTCTAAATTTGAATTTGAG ACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCTGAGTTTGATGGCTGCCTGGAATACAACCAC GAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCACATGCTGTCTCGGCTGGAGGAACTTCAGGACATC CTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACATTCTCAGCTGAAGAAGAAGGTGATTAAGGCC CCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTTCCCAAAAAGAACTCAGGCTCAGGC AATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCGACACGGCAGCATCTGCACCAGATGTGGCAT GTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATGTTTGACTGGATCACACACAACAAA GGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTTCAGACGCAGCACAATCACTTTGCCATGAAC TGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGCCACTATGCCTCGCAGCAGATCAGG CAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGGAGCACCTTGCTGGACATGTCCTCCATTTTC CACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGACCTTCCCTCAGAGCTGCAGGACCTA GAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAGCTACAAGACATTCAGTACCTGACAGAGAAC ATCTGGGCGTCCCAGTCAGTCCTCAGTGCTTGCGACAATCTCAGTGATCTGGTCATGGTCAGATGGAATAAATCCCTGGAGTGGTCCCCC TGGAACTGCATTCTTCTTACCAAAGATGAAGCAGCTGCTCATCTCAAGCTAACAAGTATTGAAGAGGGATATGAACGCTCATTTATTCAC AAGATCAAACACAAACATATCCTGGCTAAGAACTATTTTTCTCAGGTTCCAGTGCTGGCTTCATTTATACTTGATGATGGTGAAATTGAT >In-frame_TRIO_ENST00000537187_chr5_14304701_+_IQUB_ENST00000324698_chr7_123097620_-_1869nt ATGAGCGGCAGCAGCGGCGGAGCCGCCGCCCCCGCCGCGTCCTCCGGCCCCGCCGCGGCGGCCAGCGCGGCTGGCTCGGGCTGCGGGGGC GGTGCCGGCGAGGGGGCAGAGGAGGCGGCCAAGGACCTGGCCGACATCGCGGCCTTCTTCCGATCCGGGTTTCGAAAAAACGATGAAATG AAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGAGATAAACGTGGAGGTCCCATTTTAACGTTT CCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCCTGTATTCCCAGCGAGGAGGTCTGC AAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCCCTTCTGAAGATCCTGCAGGAGTCCTTCCCC TGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGGACTAATTTTGGCAGTTCTAAATTTGAATTTGAG ACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCTGAGTTTGATGGCTGCCTGGAATACAACCAC GAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCACATGCTGTCTCGGCTGGAGGAACTTCAGGACATC CTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACATTCTCAGCTGAAGAAGAAGGTGATTAAGGCC CCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTTCCCAAAAAGAACTCAGGCTCAGGC AATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCGACACGGCAGCATCTGCACCAGATGTGGCAT GTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATGTTTGACTGGATCACACACAACAAA GGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTTCAGACGCAGCACAATCACTTTGCCATGAAC TGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGCCACTATGCCTCGCAGCAGATCAGG CAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGGAGCACCTTGCTGGACATGTCCTCCATTTTC CACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGACCTTCCCTCAGAGCTGCAGGACCTA GAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAGCTACAAGACATTCAGTACCTGACAGAGAAC ATCTGGGCGTCCCAGTCAGTCCTCAGTGCTTGCGACAATCTCAGTGATCTGGTCATGGTCAGATGGAATAAATCCCTGGAGTGGTCCCCC TGGAACTGCATTCTTCTTACCAAAGATGAAGCAGCTGCTCATCTCAAGCTAACAAGTATTGAAGAGGGATATGAACGCTCATTTATTCAC AAGATCAAACACAAACATATCCTGGCTAAGAACTATTTTTCTCAGGTTCCAGTGCTGGCTTCATTTATACTTGATGATGGTGAAATTGAT >In-frame_TRIO_ENST00000509967_chr5_14304701_+_IQUB_ENST00000466202_chr7_123097620_-_1722nt ATGGCAGAAGGGTTTCGAAAAAACGATGAAATGAAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGG AGAGATAAACGTGGAGGTCCCATTTTAACGTTTCCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCC TATCTAGCCTGTATTCCCAGCGAGGAGGTCTGCAAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAG CCCCTTCTGAAGATCCTGCAGGAGTCCTTCCCCTGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGG ACTAATTTTGGCAGTTCTAAATTTGAATTTGAGACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACT CCTGAGTTTGATGGCTGCCTGGAATACAACCACGAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCAC ATGCTGTCTCGGCTGGAGGAACTTCAGGACATCCTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAA CATTCTCAGCTGAAGAAGAAGGTGATTAAGGCCCCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGT GAAAGCTTTCCCAAAAAGAACTCAGGCTCAGGCAATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCAC TCGACACGGCAGCATCTGCACCAGATGTGGCATGTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCT GAGAAGATGTTTGACTGGATCACACACAACAAAGGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAG CTTCAGACGCAGCACAATCACTTTGCCATGAACTGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTG GAGTCTGGCCACTATGCCTCGCAGCAGATCAGGCAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAG CGGAGCACCTTGCTGGACATGTCCTCCATTTTCCACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGT GAGGTAGACCTTCCCTCAGAGCTGCAGGACCTAGAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCT GAGCTACAAGACATTCAGTACCTGACAGAGAACATCTGGGCGTCCCAGTCAGTCCTCAGTGCTTGCGACAATCTCAGTGATCTGGTCATG GTCAGATGGAATAAATCCCTGGAGTGGTCCCCCTGGAACTGCATTCTTCTTACCAAAGATGAAGCAGCTGCTCATCTCAAGCTAACAAGT ATTGAAGAGGGATATGAACGCTCATTTATTCACAAGATCAAACACAAACATATCCTGGCTAAGAACTATTTTTCTCAGGTTCCAGTGCTG GCTTCATTTATACTTGATGATGGTGAAATTGATGAGATCAGATGGAAGTATCACTCAGACACAACACCTAAGATTATAGAATCCCAGAGG >In-frame_TRIO_ENST00000509967_chr5_14304701_+_IQUB_ENST00000324698_chr7_123097620_-_1722nt ATGGCAGAAGGGTTTCGAAAAAACGATGAAATGAAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGG AGAGATAAACGTGGAGGTCCCATTTTAACGTTTCCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCC TATCTAGCCTGTATTCCCAGCGAGGAGGTCTGCAAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAG CCCCTTCTGAAGATCCTGCAGGAGTCCTTCCCCTGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGG ACTAATTTTGGCAGTTCTAAATTTGAATTTGAGACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACT CCTGAGTTTGATGGCTGCCTGGAATACAACCACGAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCAC ATGCTGTCTCGGCTGGAGGAACTTCAGGACATCCTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAA CATTCTCAGCTGAAGAAGAAGGTGATTAAGGCCCCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGT GAAAGCTTTCCCAAAAAGAACTCAGGCTCAGGCAATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCAC TCGACACGGCAGCATCTGCACCAGATGTGGCATGTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCT GAGAAGATGTTTGACTGGATCACACACAACAAAGGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAG CTTCAGACGCAGCACAATCACTTTGCCATGAACTGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTG GAGTCTGGCCACTATGCCTCGCAGCAGATCAGGCAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAG CGGAGCACCTTGCTGGACATGTCCTCCATTTTCCACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGT GAGGTAGACCTTCCCTCAGAGCTGCAGGACCTAGAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCT GAGCTACAAGACATTCAGTACCTGACAGAGAACATCTGGGCGTCCCAGTCAGTCCTCAGTGCTTGCGACAATCTCAGTGATCTGGTCATG GTCAGATGGAATAAATCCCTGGAGTGGTCCCCCTGGAACTGCATTCTTCTTACCAAAGATGAAGCAGCTGCTCATCTCAAGCTAACAAGT ATTGAAGAGGGATATGAACGCTCATTTATTCACAAGATCAAACACAAACATATCCTGGCTAAGAACTATTTTTCTCAGGTTCCAGTGCTG GCTTCATTTATACTTGATGATGGTGAAATTGATGAGATCAGATGGAAGTATCACTCAGACACAACACCTAAGATTATAGAATCCCAGAGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TRIO_ENST00000344204_chr5_14304701_+_IQUB_ENST00000466202_chr7_123097620_-_2236nt GCGGCCGCGGGCGCCGCCGCAGCCATGAGCGGCAGCAGCGGCGGAGCCGCCGCCCCCGCCGCGTCCTCCGGCCCCGCCGCGGCGGCCAGC GCGGCTGGCTCGGGCTGCGGGGGCGGTGCCGGCGAGGGGGCAGAGGAGGCGGCCAAGGACCTGGCCGACATCGCGGCCTTCTTCCGATCC GGGTTTCGAAAAAACGATGAAATGAAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGAGATAAA CGTGGAGGTCCCATTTTAACGTTTCCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCC TGTATTCCCAGCGAGGAGGTCTGCAAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCCCTTCTG AAGATCCTGCAGGAGTCCTTCCCCTGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGGACTAATTTT GGCAGTTCTAAATTTGAATTTGAGACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCTGAGTTT GATGGCTGCCTGGAATACAACCACGAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCACATGCTGTCT CGGCTGGAGGAACTTCAGGACATCCTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACATTCTCAG CTGAAGAAGAAGGTGATTAAGGCCCCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTT CCCAAAAAGAACTCAGGCTCAGGCAATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCGACACGG CAGCATCTGCACCAGATGTGGCATGTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATG TTTGACTGGATCACACACAACAAAGGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTTCAGACG CAGCACAATCACTTTGCCATGAACTGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGC CACTATGCCTCGCAGCAGATCAGGCAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGGAGCACC TTGCTGGACATGTCCTCCATTTTCCACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGAC CTTCCCTCAGAGCTGCAGGACCTAGAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAGCTACAA GACATTCAGTACCTGACAGAGAACATCTGGGCGTCCCAGTCAGTCCTCAGTGCTTGCGACAATCTCAGTGATCTGGTCATGGTCAGATGG AATAAATCCCTGGAGTGGTCCCCCTGGAACTGCATTCTTCTTACCAAAGATGAAGCAGCTGCTCATCTCAAGCTAACAAGTATTGAAGAG GGATATGAACGCTCATTTATTCACAAGATCAAACACAAACATATCCTGGCTAAGAACTATTTTTCTCAGGTTCCAGTGCTGGCTTCATTT ATACTTGATGATGGTGAAATTGATGAGATCAGATGGAAGTATCACTCAGACACAACACCTAAGATTATAGAATCCCAGAGGCCTCCTCAT TAGGTGATCCAGGAGTATTTGTTTGATGATCGGCATTTTGTTCACTGCTAATAGGGTAATACAGAGGTCACAGAGTATGGAAATGGAATT TAATCTGTTTATTGATTTTGTTTTTTGTTTTTCATAGTATTTTGAGTTATATAAAGAGAAAACATTTCTATATAAGTAAGTATTCTTTGT TAGGAAGTTGGTGCTAAATTGAAATGCAATTTTGTTACTGAAATTAATATTTTGGGGTAAAGAAAACATTTTAAAATGTGTTTTCACATT >In-frame_TRIO_ENST00000344204_chr5_14304701_+_IQUB_ENST00000324698_chr7_123097620_-_2231nt GCGGCCGCGGGCGCCGCCGCAGCCATGAGCGGCAGCAGCGGCGGAGCCGCCGCCCCCGCCGCGTCCTCCGGCCCCGCCGCGGCGGCCAGC GCGGCTGGCTCGGGCTGCGGGGGCGGTGCCGGCGAGGGGGCAGAGGAGGCGGCCAAGGACCTGGCCGACATCGCGGCCTTCTTCCGATCC GGGTTTCGAAAAAACGATGAAATGAAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGAGATAAA CGTGGAGGTCCCATTTTAACGTTTCCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCC TGTATTCCCAGCGAGGAGGTCTGCAAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCCCTTCTG AAGATCCTGCAGGAGTCCTTCCCCTGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGGACTAATTTT GGCAGTTCTAAATTTGAATTTGAGACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCTGAGTTT GATGGCTGCCTGGAATACAACCACGAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCACATGCTGTCT CGGCTGGAGGAACTTCAGGACATCCTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACATTCTCAG CTGAAGAAGAAGGTGATTAAGGCCCCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTT CCCAAAAAGAACTCAGGCTCAGGCAATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCGACACGG CAGCATCTGCACCAGATGTGGCATGTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATG TTTGACTGGATCACACACAACAAAGGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTTCAGACG CAGCACAATCACTTTGCCATGAACTGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGC CACTATGCCTCGCAGCAGATCAGGCAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGGAGCACC TTGCTGGACATGTCCTCCATTTTCCACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGAC CTTCCCTCAGAGCTGCAGGACCTAGAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAGCTACAA GACATTCAGTACCTGACAGAGAACATCTGGGCGTCCCAGTCAGTCCTCAGTGCTTGCGACAATCTCAGTGATCTGGTCATGGTCAGATGG AATAAATCCCTGGAGTGGTCCCCCTGGAACTGCATTCTTCTTACCAAAGATGAAGCAGCTGCTCATCTCAAGCTAACAAGTATTGAAGAG GGATATGAACGCTCATTTATTCACAAGATCAAACACAAACATATCCTGGCTAAGAACTATTTTTCTCAGGTTCCAGTGCTGGCTTCATTT ATACTTGATGATGGTGAAATTGATGAGATCAGATGGAAGTATCACTCAGACACAACACCTAAGATTATAGAATCCCAGAGGCCTCCTCAT TAGGTGATCCAGGAGTATTTGTTTGATGATCGGCATTTTGTTCACTGCTAATAGGGTAATACAGAGGTCACAGAGTATGGAAATGGAATT TAATCTGTTTATTGATTTTGTTTTTTGTTTTTCATAGTATTTTGAGTTATATAAAGAGAAAACATTTCTATATAAGTAAGTATTCTTTGT TAGGAAGTTGGTGCTAAATTGAAATGCAATTTTGTTACTGAAATTAATATTTTGGGGTAAAGAAAACATTTTAAAATGTGTTTTCACATT >In-frame_TRIO_ENST00000537187_chr5_14304701_+_IQUB_ENST00000466202_chr7_123097620_-_2218nt GCAGCCATGAGCGGCAGCAGCGGCGGAGCCGCCGCCCCCGCCGCGTCCTCCGGCCCCGCCGCGGCGGCCAGCGCGGCTGGCTCGGGCTGC GGGGGCGGTGCCGGCGAGGGGGCAGAGGAGGCGGCCAAGGACCTGGCCGACATCGCGGCCTTCTTCCGATCCGGGTTTCGAAAAAACGAT GAAATGAAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGAGATAAACGTGGAGGTCCCATTTTA ACGTTTCCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCCTGTATTCCCAGCGAGGAG GTCTGCAAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCCCTTCTGAAGATCCTGCAGGAGTCC TTCCCCTGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGGACTAATTTTGGCAGTTCTAAATTTGAA TTTGAGACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCTGAGTTTGATGGCTGCCTGGAATAC AACCACGAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCACATGCTGTCTCGGCTGGAGGAACTTCAG GACATCCTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACATTCTCAGCTGAAGAAGAAGGTGATT AAGGCCCCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTTCCCAAAAAGAACTCAGGC TCAGGCAATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCGACACGGCAGCATCTGCACCAGATG TGGCATGTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATGTTTGACTGGATCACACAC AACAAAGGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTTCAGACGCAGCACAATCACTTTGCC ATGAACTGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGCCACTATGCCTCGCAGCAG ATCAGGCAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGGAGCACCTTGCTGGACATGTCCTCC ATTTTCCACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGACCTTCCCTCAGAGCTGCAG GACCTAGAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAGCTACAAGACATTCAGTACCTGACA GAGAACATCTGGGCGTCCCAGTCAGTCCTCAGTGCTTGCGACAATCTCAGTGATCTGGTCATGGTCAGATGGAATAAATCCCTGGAGTGG TCCCCCTGGAACTGCATTCTTCTTACCAAAGATGAAGCAGCTGCTCATCTCAAGCTAACAAGTATTGAAGAGGGATATGAACGCTCATTT ATTCACAAGATCAAACACAAACATATCCTGGCTAAGAACTATTTTTCTCAGGTTCCAGTGCTGGCTTCATTTATACTTGATGATGGTGAA ATTGATGAGATCAGATGGAAGTATCACTCAGACACAACACCTAAGATTATAGAATCCCAGAGGCCTCCTCATTAGGTGATCCAGGAGTAT TTGTTTGATGATCGGCATTTTGTTCACTGCTAATAGGGTAATACAGAGGTCACAGAGTATGGAAATGGAATTTAATCTGTTTATTGATTT TGTTTTTTGTTTTTCATAGTATTTTGAGTTATATAAAGAGAAAACATTTCTATATAAGTAAGTATTCTTTGTTAGGAAGTTGGTGCTAAA TTGAAATGCAATTTTGTTACTGAAATTAATATTTTGGGGTAAAGAAAACATTTTAAAATGTGTTTTCACATTAAATTTTTTAAATTTTTT >In-frame_TRIO_ENST00000537187_chr5_14304701_+_IQUB_ENST00000324698_chr7_123097620_-_2213nt GCAGCCATGAGCGGCAGCAGCGGCGGAGCCGCCGCCCCCGCCGCGTCCTCCGGCCCCGCCGCGGCGGCCAGCGCGGCTGGCTCGGGCTGC GGGGGCGGTGCCGGCGAGGGGGCAGAGGAGGCGGCCAAGGACCTGGCCGACATCGCGGCCTTCTTCCGATCCGGGTTTCGAAAAAACGAT GAAATGAAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGAGATAAACGTGGAGGTCCCATTTTA ACGTTTCCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCCTGTATTCCCAGCGAGGAG GTCTGCAAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCCCTTCTGAAGATCCTGCAGGAGTCC TTCCCCTGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGGACTAATTTTGGCAGTTCTAAATTTGAA TTTGAGACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCTGAGTTTGATGGCTGCCTGGAATAC AACCACGAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCACATGCTGTCTCGGCTGGAGGAACTTCAG GACATCCTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACATTCTCAGCTGAAGAAGAAGGTGATT AAGGCCCCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTTCCCAAAAAGAACTCAGGC TCAGGCAATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCGACACGGCAGCATCTGCACCAGATG TGGCATGTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATGTTTGACTGGATCACACAC AACAAAGGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTTCAGACGCAGCACAATCACTTTGCC ATGAACTGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGCCACTATGCCTCGCAGCAG ATCAGGCAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGGAGCACCTTGCTGGACATGTCCTCC ATTTTCCACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGACCTTCCCTCAGAGCTGCAG GACCTAGAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAGCTACAAGACATTCAGTACCTGACA GAGAACATCTGGGCGTCCCAGTCAGTCCTCAGTGCTTGCGACAATCTCAGTGATCTGGTCATGGTCAGATGGAATAAATCCCTGGAGTGG TCCCCCTGGAACTGCATTCTTCTTACCAAAGATGAAGCAGCTGCTCATCTCAAGCTAACAAGTATTGAAGAGGGATATGAACGCTCATTT ATTCACAAGATCAAACACAAACATATCCTGGCTAAGAACTATTTTTCTCAGGTTCCAGTGCTGGCTTCATTTATACTTGATGATGGTGAA ATTGATGAGATCAGATGGAAGTATCACTCAGACACAACACCTAAGATTATAGAATCCCAGAGGCCTCCTCATTAGGTGATCCAGGAGTAT TTGTTTGATGATCGGCATTTTGTTCACTGCTAATAGGGTAATACAGAGGTCACAGAGTATGGAAATGGAATTTAATCTGTTTATTGATTT TGTTTTTTGTTTTTCATAGTATTTTGAGTTATATAAAGAGAAAACATTTCTATATAAGTAAGTATTCTTTGTTAGGAAGTTGGTGCTAAA TTGAAATGCAATTTTGTTACTGAAATTAATATTTTGGGGTAAAGAAAACATTTTAAAATGTGTTTTCACATTAAATTTTTTAAATTTTTT >In-frame_TRIO_ENST00000509967_chr5_14304701_+_IQUB_ENST00000466202_chr7_123097620_-_2217nt ATTTGGGATATCTAGAGGTTGTTTGTTGGTGTTCTGGGATCCTGAGGGACACTGCCAACTGTTAACCTTTGGCAGATAGTGACTGTTTTA CTTCGATTTTATTTTCGTGGTAACCGTTTTTTAAAAAAGATTAATAAATTACCCAAGAGGACATGGCAGAAGGGTTTCGAAAAAACGATG AAATGAAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGAGATAAACGTGGAGGTCCCATTTTAA CGTTTCCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCCTGTATTCCCAGCGAGGAGG TCTGCAAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCCCTTCTGAAGATCCTGCAGGAGTCCT TCCCCTGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGGACTAATTTTGGCAGTTCTAAATTTGAAT TTGAGACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCTGAGTTTGATGGCTGCCTGGAATACA ACCACGAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCACATGCTGTCTCGGCTGGAGGAACTTCAGG ACATCCTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACATTCTCAGCTGAAGAAGAAGGTGATTA AGGCCCCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTTCCCAAAAAGAACTCAGGCT CAGGCAATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCGACACGGCAGCATCTGCACCAGATGT GGCATGTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATGTTTGACTGGATCACACACA ACAAAGGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTTCAGACGCAGCACAATCACTTTGCCA TGAACTGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGCCACTATGCCTCGCAGCAGA TCAGGCAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGGAGCACCTTGCTGGACATGTCCTCCA TTTTCCACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGACCTTCCCTCAGAGCTGCAGG ACCTAGAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAGCTACAAGACATTCAGTACCTGACAG AGAACATCTGGGCGTCCCAGTCAGTCCTCAGTGCTTGCGACAATCTCAGTGATCTGGTCATGGTCAGATGGAATAAATCCCTGGAGTGGT CCCCCTGGAACTGCATTCTTCTTACCAAAGATGAAGCAGCTGCTCATCTCAAGCTAACAAGTATTGAAGAGGGATATGAACGCTCATTTA TTCACAAGATCAAACACAAACATATCCTGGCTAAGAACTATTTTTCTCAGGTTCCAGTGCTGGCTTCATTTATACTTGATGATGGTGAAA TTGATGAGATCAGATGGAAGTATCACTCAGACACAACACCTAAGATTATAGAATCCCAGAGGCCTCCTCATTAGGTGATCCAGGAGTATT TGTTTGATGATCGGCATTTTGTTCACTGCTAATAGGGTAATACAGAGGTCACAGAGTATGGAAATGGAATTTAATCTGTTTATTGATTTT GTTTTTTGTTTTTCATAGTATTTTGAGTTATATAAAGAGAAAACATTTCTATATAAGTAAGTATTCTTTGTTAGGAAGTTGGTGCTAAAT TGAAATGCAATTTTGTTACTGAAATTAATATTTTGGGGTAAAGAAAACATTTTAAAATGTGTTTTCACATTAAATTTTTTAAATTTTTTC >In-frame_TRIO_ENST00000509967_chr5_14304701_+_IQUB_ENST00000324698_chr7_123097620_-_2212nt ATTTGGGATATCTAGAGGTTGTTTGTTGGTGTTCTGGGATCCTGAGGGACACTGCCAACTGTTAACCTTTGGCAGATAGTGACTGTTTTA CTTCGATTTTATTTTCGTGGTAACCGTTTTTTAAAAAAGATTAATAAATTACCCAAGAGGACATGGCAGAAGGGTTTCGAAAAAACGATG AAATGAAAGCTATGGATGTTTTACCAATTTTGAAGGAAAAAGTTGCATACCTTTCAGGTGGGAGAGATAAACGTGGAGGTCCCATTTTAA CGTTTCCGGCCCGCAGCAATCATGACAGAATACGACAGGAGGATCTCAGGAGACTCATTTCCTATCTAGCCTGTATTCCCAGCGAGGAGG TCTGCAAGCGTGGCTTCACGGTGATCGTGGACATGCGTGGGTCCAAGTGGGACTCCATCAAGCCCCTTCTGAAGATCCTGCAGGAGTCCT TCCCCTGCTGCATCCATGTGGCCCTGATCATCAAGCCAGACAACTTCTGGCAGAAACAGAGGACTAATTTTGGCAGTTCTAAATTTGAAT TTGAGACAAATATGGTCTCTTTAGAAGGCCTTACCAAAGTAGTTGATCCTTCTCAGCTAACTCCTGAGTTTGATGGCTGCCTGGAATACA ACCACGAAGAATGGATTGAAATCAGAGTTGCTTTTGAAGACTACATTAGCAATGCCACCCACATGCTGTCTCGGCTGGAGGAACTTCAGG ACATCCTAGCTAAGAAGGAGCTGCCTCAGGATTTAGAGGGGGCTCGGAATATGATCGAGGAACATTCTCAGCTGAAGAAGAAGGTGATTA AGGCCCCCATCGAGGACCTGGATTTGGAGGGACAGAAGCTGCTTCAGAGGATACAGAGCAGTGAAAGCTTTCCCAAAAAGAACTCAGGCT CAGGCAATGCGGACCTGCAGAACCTCTTGCCCAAGGTGTCCACCATGCTGGACCGGCTGCACTCGACACGGCAGCATCTGCACCAGATGT GGCATGTGAGGAAGCTGAAGCTGGACCAGTGCTTCCAGCTGAGGCTGTTTGAACAGGATGCTGAGAAGATGTTTGACTGGATCACACACA ACAAAGGCCTGTTTCTAAACAGCTACACAGAGATTGGGACCAGCCACCCTCATGCCATGGAGCTTCAGACGCAGCACAATCACTTTGCCA TGAACTGTATGAACGTGTATGTAAATATAAACCGCATCATGTCGGTGGCCAATCGTCTGGTGGAGTCTGGCCACTATGCCTCGCAGCAGA TCAGGCAGATCGCGAGTCAGCTGGAGCAGGAGTGGAAGGCGTTTGCGGCAGCCCTGGATGAGCGGAGCACCTTGCTGGACATGTCCTCCA TTTTCCACCAGAAGGCCGAAAAGTATATGAGCAACGTGGATTCATGGTGTAAAGCTTGCGGTGAGGTAGACCTTCCCTCAGAGCTGCAGG ACCTAGAAGATGCCATTCATCACCACCAGGGAATATATGAACATATCACTCTTGCTTATTCTGAGCTACAAGACATTCAGTACCTGACAG AGAACATCTGGGCGTCCCAGTCAGTCCTCAGTGCTTGCGACAATCTCAGTGATCTGGTCATGGTCAGATGGAATAAATCCCTGGAGTGGT CCCCCTGGAACTGCATTCTTCTTACCAAAGATGAAGCAGCTGCTCATCTCAAGCTAACAAGTATTGAAGAGGGATATGAACGCTCATTTA TTCACAAGATCAAACACAAACATATCCTGGCTAAGAACTATTTTTCTCAGGTTCCAGTGCTGGCTTCATTTATACTTGATGATGGTGAAA TTGATGAGATCAGATGGAAGTATCACTCAGACACAACACCTAAGATTATAGAATCCCAGAGGCCTCCTCATTAGGTGATCCAGGAGTATT TGTTTGATGATCGGCATTTTGTTCACTGCTAATAGGGTAATACAGAGGTCACAGAGTATGGAAATGGAATTTAATCTGTTTATTGATTTT GTTTTTTGTTTTTCATAGTATTTTGAGTTATATAAAGAGAAAACATTTCTATATAAGTAAGTATTCTTTGTTAGGAAGTTGGTGCTAAAT TGAAATGCAATTTTGTTACTGAAATTAATATTTTGGGGTAAAGAAAACATTTTAAAATGTGTTTTCACATTAAATTTTTTAAATTTTTTC |
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FusionGenePPI for TRIO_IQUB |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TRIO | FLNA, BLMH, RAC1, PTPRF, RHOA, CDC5L, DISC1, EXOC1, ITSN2, BCAS2, DAB2, NAV1, NAV2, NAV3, RHOG, MAPRE1, NTRK1, CFAP45, PPM1F, RPE, SSU72, CENPJ, MYC, ZSCAN26, PTPRD, PTPRS, ZNF232, ZNF785, TRIM25 | IQUB | MDFI, TRIM23, MAGEA6, TRIM27, TRAF2, BLZF1, DYNLL1, TMCC2, TRIM54, SYCE1, KRT40, IQUB, TRIM42, CCDC36, KRTAP10-7, KRTAP10-9, KRTAP10-3, KRTAP12-4, PIK3R3, TLR6, BTBD1, FAM107A |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TRIO_IQUB |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TRIO_IQUB |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | TRIO | C0023467 | Leukemia, Myelocytic, Acute | 1 | CTD_human |
| Hgene | TRIO | C0023903 | Liver neoplasms | 1 | CTD_human |
| Hgene | TRIO | C0032927 | Precancerous Conditions | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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