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Fusion gene ID: 38727 |
FusionGeneSummary for TMOD2_C15orf59 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: TMOD2_C15orf59 | Fusion gene ID: 38727 | Hgene | Tgene | Gene symbol | TMOD2 | C15orf59 | Gene ID | 29767 |
| Gene name | tropomodulin 2 | ||
| Synonyms | N-TMOD|NTMOD | ||
| Cytomap | 15q21.2 | ||
| Type of gene | protein-coding | ||
| Description | tropomodulin-2neuronal tropomodulintropomodulin 2 (neuronal) | ||
| Modification date | 20180523 | ||
| UniProtAcc | Q9NZR1 | Q2T9L4 | |
| Ensembl transtripts involved in fusion gene | ENST00000249700, ENST00000539962, ENST00000435126, | ENST00000569673, ENST00000379822, ENST00000558834, | |
| Fusion gene scores | * DoF score | 1 X 1 X 1=1 | 3 X 1 X 2=6 |
| # samples | 1 | 2 | |
| ** MAII score | log2(1/1*10)=3.32192809488736 | log2(2/6*10)=1.73696559416621 | |
| Context | PubMed: TMOD2 [Title/Abstract] AND C15orf59 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LGG | TCGA-DU-A7TC-01A | TMOD2 | chr15 | 52075025 | + | C15orf59 | chr15 | 74032983 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000249700 | ENST00000569673 | TMOD2 | chr15 | 52075025 | + | C15orf59 | chr15 | 74032983 | - |
| In-frame | ENST00000249700 | ENST00000379822 | TMOD2 | chr15 | 52075025 | + | C15orf59 | chr15 | 74032983 | - |
| 5CDS-intron | ENST00000249700 | ENST00000558834 | TMOD2 | chr15 | 52075025 | + | C15orf59 | chr15 | 74032983 | - |
| In-frame | ENST00000539962 | ENST00000569673 | TMOD2 | chr15 | 52075025 | + | C15orf59 | chr15 | 74032983 | - |
| In-frame | ENST00000539962 | ENST00000379822 | TMOD2 | chr15 | 52075025 | + | C15orf59 | chr15 | 74032983 | - |
| 5CDS-intron | ENST00000539962 | ENST00000558834 | TMOD2 | chr15 | 52075025 | + | C15orf59 | chr15 | 74032983 | - |
| intron-3CDS | ENST00000435126 | ENST00000569673 | TMOD2 | chr15 | 52075025 | + | C15orf59 | chr15 | 74032983 | - |
| intron-3CDS | ENST00000435126 | ENST00000379822 | TMOD2 | chr15 | 52075025 | + | C15orf59 | chr15 | 74032983 | - |
| intron-intron | ENST00000435126 | ENST00000558834 | TMOD2 | chr15 | 52075025 | + | C15orf59 | chr15 | 74032983 | - |
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FusionProtFeatures for TMOD2_C15orf59 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| TMOD2 | C15orf59 |
| Blocks the elongation and depolymerization of the actinfilaments at the pointed end. The Tmod/TM complex contributes tothe formation of the short actin protofilament, which in turndefines the geometry of the membrane skeleton (By similarity).{ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >C15orf59 | chr15:52075025 | chr15:74032983 | ENST00000379822 | - | 0 | 2 | 207_214 | 52 | 294 | Compositional bias | Note=Poly-Glu |
| Tgene | >C15orf59 | chr15:52075025 | chr15:74032983 | ENST00000569673 | - | 1 | 3 | 207_214 | 52 | 294 | Compositional bias | Note=Poly-Glu |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | C15orf59 | chr15:52075025 | chr15:74032983 | ENST00000379822 | - | 0 | 2 | 30_63 | 52 | 294 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | C15orf59 | chr15:52075025 | chr15:74032983 | ENST00000569673 | - | 1 | 3 | 30_63 | 52 | 294 | Coiled coil | Ontology_term=ECO:0000255 |
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FusionGeneSequence for TMOD2_C15orf59 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_TMOD2_ENST00000249700_chr15_52075025_+_C15orf59_ENST00000569673_chr15_74032983_-_486aa MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALEQKDREDFVPFT GEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP NPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIVVSQIDKLTSDFDFELEPDDWTTATV SSTSSSDKAGMGGPFDLGHLDFMTADILSDSWEFCSFLDVSTPSDSVDGPESTRPGAGPDYRLMNGGTPIPNGPRVETPDSSSEEAFGAG PTVKSQLPQRTPGTRERVRFSDKVLYHALCCDDEEGDGEQEVEEEEVGLPPEPAHTEAHAGPHKPSPAPYKSRRSPLTSRHSGSTLAPEQ >In-frame_TMOD2_ENST00000249700_chr15_52075025_+_C15orf59_ENST00000379822_chr15_74032983_-_486aa MALPFQKELEKYKNIDEDELLGKLSEEELKQLENVLDDLDPESAMLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALEQKDREDFVPFT GEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDLAAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPP NPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALETNTHVKKFSLAATRSNDPVAIVVSQIDKLTSDFDFELEPDDWTTATV SSTSSSDKAGMGGPFDLGHLDFMTADILSDSWEFCSFLDVSTPSDSVDGPESTRPGAGPDYRLMNGGTPIPNGPRVETPDSSSEEAFGAG PTVKSQLPQRTPGTRERVRFSDKVLYHALCCDDEEGDGEQEVEEEEVGLPPEPAHTEAHAGPHKPSPAPYKSRRSPLTSRHSGSTLAPEQ >In-frame_TMOD2_ENST00000539962_chr15_52075025_+_C15orf59_ENST00000569673_chr15_74032983_-_442aa MLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDL AAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALET NTHVKKFSLAATRSNDPVAIVVSQIDKLTSDFDFELEPDDWTTATVSSTSSSDKAGMGGPFDLGHLDFMTADILSDSWEFCSFLDVSTPS DSVDGPESTRPGAGPDYRLMNGGTPIPNGPRVETPDSSSEEAFGAGPTVKSQLPQRTPGTRERVRFSDKVLYHALCCDDEEGDGEQEVEE >In-frame_TMOD2_ENST00000539962_chr15_52075025_+_C15orf59_ENST00000379822_chr15_74032983_-_442aa MLPAGFRQKDQTQKAATGPFDREHLLMYLEKEALEQKDREDFVPFTGEKKGRVFIPKEKPIETRKEEKVTLDPELEEALASASDTELYDL AAVLGVHNLLNNPKFDEETANNKGGKGPVRNVVKGEKVKPVFEEPPNPTNVEISLQQMKANDPSLQEVNLNNIKNIPIPTLREFAKALET NTHVKKFSLAATRSNDPVAIVVSQIDKLTSDFDFELEPDDWTTATVSSTSSSDKAGMGGPFDLGHLDFMTADILSDSWEFCSFLDVSTPS DSVDGPESTRPGAGPDYRLMNGGTPIPNGPRVETPDSSSEEAFGAGPTVKSQLPQRTPGTRERVRFSDKVLYHALCCDDEEGDGEQEVEE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_TMOD2_ENST00000249700_chr15_52075025_+_C15orf59_ENST00000569673_chr15_74032983_-_1458nt ATGGCACTCCCCTTTCAAAAAGAGCTGGAGAAATACAAGAACATTGATGAAGATGAGCTTCTTGGCAAACTCTCAGAAGAGGAACTGAAA CAGTTGGAAAATGTTCTAGATGACCTAGATCCTGAGAGTGCCATGCTGCCAGCTGGATTTCGACAGAAAGACCAGACACAGAAGGCAGCC ACCGGCCCCTTTGACCGCGAGCACCTCCTCATGTACCTGGAGAAGGAGGCTTTGGAACAGAAAGACAGAGAGGACTTTGTGCCCTTCACT GGAGAAAAGAAAGGGAGAGTCTTTATCCCTAAAGAAAAGCCTATAGAAACTCGTAAAGAAGAAAAAGTGACCCTTGACCCAGAACTGGAA GAAGCTTTGGCCAGTGCCTCTGACACCGAACTCTATGATCTTGCAGCTGTCCTTGGAGTACACAATTTGCTCAACAATCCAAAGTTCGAT GAAGAAACAGCCAACAATAAAGGTGGCAAAGGACCTGTCAGAAATGTTGTCAAAGGTGAAAAAGTAAAGCCAGTATTTGAGGAACCACCA AATCCCACAAATGTGGAAATAAGCCTGCAGCAGATGAAAGCCAATGATCCTAGCTTGCAAGAAGTCAACCTCAACAACATTAAGAACATT CCAATTCCAACCCTGAGGGAATTTGCAAAGGCTCTGGAGACCAACACTCACGTGAAGAAGTTCAGCCTGGCCGCAACTCGCAGCAATGAC CCTGTGGCCATTGTGGTGAGCCAGATCGATAAGCTAACCTCGGACTTCGACTTTGAACTGGAGCCGGACGACTGGACCACGGCCACTGTG AGCAGCACCTCTAGCAGTGACAAGGCGGGCATGGGTGGCCCCTTTGACCTGGGCCACCTGGACTTCATGACAGCCGATATCCTCTCAGAC AGCTGGGAGTTCTGCTCCTTCCTGGACGTCTCTACCCCCTCGGACTCCGTGGATGGTCCCGAGTCGACTCGGCCAGGGGCTGGCCCTGAC TACCGCCTCATGAATGGTGGCACGCCCATCCCCAATGGGCCACGAGTGGAGACCCCAGACTCCTCCAGTGAGGAGGCCTTTGGTGCTGGC CCCACGGTGAAGAGCCAGCTGCCCCAGCGGACCCCAGGGACACGGGAGAGGGTGCGGTTCAGTGACAAAGTGCTCTACCATGCTCTGTGC TGTGACGATGAGGAGGGGGACGGTGAGCAGGAGGTGGAGGAGGAAGAAGTGGGCTTGCCCCCTGAGCCTGCCCATACAGAGGCCCATGCA GGCCCCCACAAGCCCTCCCCAGCCCCCTACAAGTCACGGCGCTCTCCACTGACCAGCCGCCACTCAGGCTCTACCTTGGCCCCTGAACAG ACTCGAAGGGTCACGAGGAACAGCAGCACCCAGACAGTGTCAGACAAGAGCACGCAGACGGTTCTGCCCTACACAGCCACTAGACAGAAA >In-frame_TMOD2_ENST00000249700_chr15_52075025_+_C15orf59_ENST00000379822_chr15_74032983_-_1458nt ATGGCACTCCCCTTTCAAAAAGAGCTGGAGAAATACAAGAACATTGATGAAGATGAGCTTCTTGGCAAACTCTCAGAAGAGGAACTGAAA CAGTTGGAAAATGTTCTAGATGACCTAGATCCTGAGAGTGCCATGCTGCCAGCTGGATTTCGACAGAAAGACCAGACACAGAAGGCAGCC ACCGGCCCCTTTGACCGCGAGCACCTCCTCATGTACCTGGAGAAGGAGGCTTTGGAACAGAAAGACAGAGAGGACTTTGTGCCCTTCACT GGAGAAAAGAAAGGGAGAGTCTTTATCCCTAAAGAAAAGCCTATAGAAACTCGTAAAGAAGAAAAAGTGACCCTTGACCCAGAACTGGAA GAAGCTTTGGCCAGTGCCTCTGACACCGAACTCTATGATCTTGCAGCTGTCCTTGGAGTACACAATTTGCTCAACAATCCAAAGTTCGAT GAAGAAACAGCCAACAATAAAGGTGGCAAAGGACCTGTCAGAAATGTTGTCAAAGGTGAAAAAGTAAAGCCAGTATTTGAGGAACCACCA AATCCCACAAATGTGGAAATAAGCCTGCAGCAGATGAAAGCCAATGATCCTAGCTTGCAAGAAGTCAACCTCAACAACATTAAGAACATT CCAATTCCAACCCTGAGGGAATTTGCAAAGGCTCTGGAGACCAACACTCACGTGAAGAAGTTCAGCCTGGCCGCAACTCGCAGCAATGAC CCTGTGGCCATTGTGGTGAGCCAGATCGATAAGCTAACCTCGGACTTCGACTTTGAACTGGAGCCGGACGACTGGACCACGGCCACTGTG AGCAGCACCTCTAGCAGTGACAAGGCGGGCATGGGTGGCCCCTTTGACCTGGGCCACCTGGACTTCATGACAGCCGATATCCTCTCAGAC AGCTGGGAGTTCTGCTCCTTCCTGGACGTCTCTACCCCCTCGGACTCCGTGGATGGTCCCGAGTCGACTCGGCCAGGGGCTGGCCCTGAC TACCGCCTCATGAATGGTGGCACGCCCATCCCCAATGGGCCACGAGTGGAGACCCCAGACTCCTCCAGTGAGGAGGCCTTTGGTGCTGGC CCCACGGTGAAGAGCCAGCTGCCCCAGCGGACCCCAGGGACACGGGAGAGGGTGCGGTTCAGTGACAAAGTGCTCTACCATGCTCTGTGC TGTGACGATGAGGAGGGGGACGGTGAGCAGGAGGTGGAGGAGGAAGAAGTGGGCTTGCCCCCTGAGCCTGCCCATACAGAGGCCCATGCA GGCCCCCACAAGCCCTCCCCAGCCCCCTACAAGTCACGGCGCTCTCCACTGACCAGCCGCCACTCAGGCTCTACCTTGGCCCCTGAACAG ACTCGAAGGGTCACGAGGAACAGCAGCACCCAGACAGTGTCAGACAAGAGCACGCAGACGGTTCTGCCCTACACAGCCACTAGACAGAAA >In-frame_TMOD2_ENST00000539962_chr15_52075025_+_C15orf59_ENST00000569673_chr15_74032983_-_1326nt ATGCTGCCAGCTGGATTTCGACAGAAAGACCAGACACAGAAGGCAGCCACCGGCCCCTTTGACCGCGAGCACCTCCTCATGTACCTGGAG AAGGAGGCTTTGGAACAGAAAGACAGAGAGGACTTTGTGCCCTTCACTGGAGAAAAGAAAGGGAGAGTCTTTATCCCTAAAGAAAAGCCT ATAGAAACTCGTAAAGAAGAAAAAGTGACCCTTGACCCAGAACTGGAAGAAGCTTTGGCCAGTGCCTCTGACACCGAACTCTATGATCTT GCAGCTGTCCTTGGAGTACACAATTTGCTCAACAATCCAAAGTTCGATGAAGAAACAGCCAACAATAAAGGTGGCAAAGGACCTGTCAGA AATGTTGTCAAAGGTGAAAAAGTAAAGCCAGTATTTGAGGAACCACCAAATCCCACAAATGTGGAAATAAGCCTGCAGCAGATGAAAGCC AATGATCCTAGCTTGCAAGAAGTCAACCTCAACAACATTAAGAACATTCCAATTCCAACCCTGAGGGAATTTGCAAAGGCTCTGGAGACC AACACTCACGTGAAGAAGTTCAGCCTGGCCGCAACTCGCAGCAATGACCCTGTGGCCATTGTGGTGAGCCAGATCGATAAGCTAACCTCG GACTTCGACTTTGAACTGGAGCCGGACGACTGGACCACGGCCACTGTGAGCAGCACCTCTAGCAGTGACAAGGCGGGCATGGGTGGCCCC TTTGACCTGGGCCACCTGGACTTCATGACAGCCGATATCCTCTCAGACAGCTGGGAGTTCTGCTCCTTCCTGGACGTCTCTACCCCCTCG GACTCCGTGGATGGTCCCGAGTCGACTCGGCCAGGGGCTGGCCCTGACTACCGCCTCATGAATGGTGGCACGCCCATCCCCAATGGGCCA CGAGTGGAGACCCCAGACTCCTCCAGTGAGGAGGCCTTTGGTGCTGGCCCCACGGTGAAGAGCCAGCTGCCCCAGCGGACCCCAGGGACA CGGGAGAGGGTGCGGTTCAGTGACAAAGTGCTCTACCATGCTCTGTGCTGTGACGATGAGGAGGGGGACGGTGAGCAGGAGGTGGAGGAG GAAGAAGTGGGCTTGCCCCCTGAGCCTGCCCATACAGAGGCCCATGCAGGCCCCCACAAGCCCTCCCCAGCCCCCTACAAGTCACGGCGC TCTCCACTGACCAGCCGCCACTCAGGCTCTACCTTGGCCCCTGAACAGACTCGAAGGGTCACGAGGAACAGCAGCACCCAGACAGTGTCA >In-frame_TMOD2_ENST00000539962_chr15_52075025_+_C15orf59_ENST00000379822_chr15_74032983_-_1326nt ATGCTGCCAGCTGGATTTCGACAGAAAGACCAGACACAGAAGGCAGCCACCGGCCCCTTTGACCGCGAGCACCTCCTCATGTACCTGGAG AAGGAGGCTTTGGAACAGAAAGACAGAGAGGACTTTGTGCCCTTCACTGGAGAAAAGAAAGGGAGAGTCTTTATCCCTAAAGAAAAGCCT ATAGAAACTCGTAAAGAAGAAAAAGTGACCCTTGACCCAGAACTGGAAGAAGCTTTGGCCAGTGCCTCTGACACCGAACTCTATGATCTT GCAGCTGTCCTTGGAGTACACAATTTGCTCAACAATCCAAAGTTCGATGAAGAAACAGCCAACAATAAAGGTGGCAAAGGACCTGTCAGA AATGTTGTCAAAGGTGAAAAAGTAAAGCCAGTATTTGAGGAACCACCAAATCCCACAAATGTGGAAATAAGCCTGCAGCAGATGAAAGCC AATGATCCTAGCTTGCAAGAAGTCAACCTCAACAACATTAAGAACATTCCAATTCCAACCCTGAGGGAATTTGCAAAGGCTCTGGAGACC AACACTCACGTGAAGAAGTTCAGCCTGGCCGCAACTCGCAGCAATGACCCTGTGGCCATTGTGGTGAGCCAGATCGATAAGCTAACCTCG GACTTCGACTTTGAACTGGAGCCGGACGACTGGACCACGGCCACTGTGAGCAGCACCTCTAGCAGTGACAAGGCGGGCATGGGTGGCCCC TTTGACCTGGGCCACCTGGACTTCATGACAGCCGATATCCTCTCAGACAGCTGGGAGTTCTGCTCCTTCCTGGACGTCTCTACCCCCTCG GACTCCGTGGATGGTCCCGAGTCGACTCGGCCAGGGGCTGGCCCTGACTACCGCCTCATGAATGGTGGCACGCCCATCCCCAATGGGCCA CGAGTGGAGACCCCAGACTCCTCCAGTGAGGAGGCCTTTGGTGCTGGCCCCACGGTGAAGAGCCAGCTGCCCCAGCGGACCCCAGGGACA CGGGAGAGGGTGCGGTTCAGTGACAAAGTGCTCTACCATGCTCTGTGCTGTGACGATGAGGAGGGGGACGGTGAGCAGGAGGTGGAGGAG GAAGAAGTGGGCTTGCCCCCTGAGCCTGCCCATACAGAGGCCCATGCAGGCCCCCACAAGCCCTCCCCAGCCCCCTACAAGTCACGGCGC TCTCCACTGACCAGCCGCCACTCAGGCTCTACCTTGGCCCCTGAACAGACTCGAAGGGTCACGAGGAACAGCAGCACCCAGACAGTGTCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_TMOD2_ENST00000249700_chr15_52075025_+_C15orf59_ENST00000569673_chr15_74032983_-_1796nt GCGCGCCCCGGCGCCGCGCCCGGCCGGGAGCCGCCTGTTGATCGCCGCGCTCGCCCCGGCCACGGCGCCGCCCCTGTTCTCCCGGCCCCG CTCCACCGGGGCTGACGGACTGACGGCCAGCACAGCCGGCTCCGGGATGAGCGCACGGACGGTATTCTGAAGTCTCAGGAAACTGGACCA TTTAAATGTGCATGGCCCATGAGAAAGGCTTATAAGAAGCCATGGCACTCCCCTTTCAAAAAGAGCTGGAGAAATACAAGAACATTGATG AAGATGAGCTTCTTGGCAAACTCTCAGAAGAGGAACTGAAACAGTTGGAAAATGTTCTAGATGACCTAGATCCTGAGAGTGCCATGCTGC CAGCTGGATTTCGACAGAAAGACCAGACACAGAAGGCAGCCACCGGCCCCTTTGACCGCGAGCACCTCCTCATGTACCTGGAGAAGGAGG CTTTGGAACAGAAAGACAGAGAGGACTTTGTGCCCTTCACTGGAGAAAAGAAAGGGAGAGTCTTTATCCCTAAAGAAAAGCCTATAGAAA CTCGTAAAGAAGAAAAAGTGACCCTTGACCCAGAACTGGAAGAAGCTTTGGCCAGTGCCTCTGACACCGAACTCTATGATCTTGCAGCTG TCCTTGGAGTACACAATTTGCTCAACAATCCAAAGTTCGATGAAGAAACAGCCAACAATAAAGGTGGCAAAGGACCTGTCAGAAATGTTG TCAAAGGTGAAAAAGTAAAGCCAGTATTTGAGGAACCACCAAATCCCACAAATGTGGAAATAAGCCTGCAGCAGATGAAAGCCAATGATC CTAGCTTGCAAGAAGTCAACCTCAACAACATTAAGAACATTCCAATTCCAACCCTGAGGGAATTTGCAAAGGCTCTGGAGACCAACACTC ACGTGAAGAAGTTCAGCCTGGCCGCAACTCGCAGCAATGACCCTGTGGCCATTGTGGTGAGCCAGATCGATAAGCTAACCTCGGACTTCG ACTTTGAACTGGAGCCGGACGACTGGACCACGGCCACTGTGAGCAGCACCTCTAGCAGTGACAAGGCGGGCATGGGTGGCCCCTTTGACC TGGGCCACCTGGACTTCATGACAGCCGATATCCTCTCAGACAGCTGGGAGTTCTGCTCCTTCCTGGACGTCTCTACCCCCTCGGACTCCG TGGATGGTCCCGAGTCGACTCGGCCAGGGGCTGGCCCTGACTACCGCCTCATGAATGGTGGCACGCCCATCCCCAATGGGCCACGAGTGG AGACCCCAGACTCCTCCAGTGAGGAGGCCTTTGGTGCTGGCCCCACGGTGAAGAGCCAGCTGCCCCAGCGGACCCCAGGGACACGGGAGA GGGTGCGGTTCAGTGACAAAGTGCTCTACCATGCTCTGTGCTGTGACGATGAGGAGGGGGACGGTGAGCAGGAGGTGGAGGAGGAAGAAG TGGGCTTGCCCCCTGAGCCTGCCCATACAGAGGCCCATGCAGGCCCCCACAAGCCCTCCCCAGCCCCCTACAAGTCACGGCGCTCTCCAC TGACCAGCCGCCACTCAGGCTCTACCTTGGCCCCTGAACAGACTCGAAGGGTCACGAGGAACAGCAGCACCCAGACAGTGTCAGACAAGA GCACGCAGACGGTTCTGCCCTACACAGCCACTAGACAGAAAGCCAGGGGGAAAAACTAGGGGCCGGGGAGGGGGCCGGGGGCGGTGGGCA >In-frame_TMOD2_ENST00000249700_chr15_52075025_+_C15orf59_ENST00000379822_chr15_74032983_-_1785nt GCGCGCCCCGGCGCCGCGCCCGGCCGGGAGCCGCCTGTTGATCGCCGCGCTCGCCCCGGCCACGGCGCCGCCCCTGTTCTCCCGGCCCCG CTCCACCGGGGCTGACGGACTGACGGCCAGCACAGCCGGCTCCGGGATGAGCGCACGGACGGTATTCTGAAGTCTCAGGAAACTGGACCA TTTAAATGTGCATGGCCCATGAGAAAGGCTTATAAGAAGCCATGGCACTCCCCTTTCAAAAAGAGCTGGAGAAATACAAGAACATTGATG AAGATGAGCTTCTTGGCAAACTCTCAGAAGAGGAACTGAAACAGTTGGAAAATGTTCTAGATGACCTAGATCCTGAGAGTGCCATGCTGC CAGCTGGATTTCGACAGAAAGACCAGACACAGAAGGCAGCCACCGGCCCCTTTGACCGCGAGCACCTCCTCATGTACCTGGAGAAGGAGG CTTTGGAACAGAAAGACAGAGAGGACTTTGTGCCCTTCACTGGAGAAAAGAAAGGGAGAGTCTTTATCCCTAAAGAAAAGCCTATAGAAA CTCGTAAAGAAGAAAAAGTGACCCTTGACCCAGAACTGGAAGAAGCTTTGGCCAGTGCCTCTGACACCGAACTCTATGATCTTGCAGCTG TCCTTGGAGTACACAATTTGCTCAACAATCCAAAGTTCGATGAAGAAACAGCCAACAATAAAGGTGGCAAAGGACCTGTCAGAAATGTTG TCAAAGGTGAAAAAGTAAAGCCAGTATTTGAGGAACCACCAAATCCCACAAATGTGGAAATAAGCCTGCAGCAGATGAAAGCCAATGATC CTAGCTTGCAAGAAGTCAACCTCAACAACATTAAGAACATTCCAATTCCAACCCTGAGGGAATTTGCAAAGGCTCTGGAGACCAACACTC ACGTGAAGAAGTTCAGCCTGGCCGCAACTCGCAGCAATGACCCTGTGGCCATTGTGGTGAGCCAGATCGATAAGCTAACCTCGGACTTCG ACTTTGAACTGGAGCCGGACGACTGGACCACGGCCACTGTGAGCAGCACCTCTAGCAGTGACAAGGCGGGCATGGGTGGCCCCTTTGACC TGGGCCACCTGGACTTCATGACAGCCGATATCCTCTCAGACAGCTGGGAGTTCTGCTCCTTCCTGGACGTCTCTACCCCCTCGGACTCCG TGGATGGTCCCGAGTCGACTCGGCCAGGGGCTGGCCCTGACTACCGCCTCATGAATGGTGGCACGCCCATCCCCAATGGGCCACGAGTGG AGACCCCAGACTCCTCCAGTGAGGAGGCCTTTGGTGCTGGCCCCACGGTGAAGAGCCAGCTGCCCCAGCGGACCCCAGGGACACGGGAGA GGGTGCGGTTCAGTGACAAAGTGCTCTACCATGCTCTGTGCTGTGACGATGAGGAGGGGGACGGTGAGCAGGAGGTGGAGGAGGAAGAAG TGGGCTTGCCCCCTGAGCCTGCCCATACAGAGGCCCATGCAGGCCCCCACAAGCCCTCCCCAGCCCCCTACAAGTCACGGCGCTCTCCAC TGACCAGCCGCCACTCAGGCTCTACCTTGGCCCCTGAACAGACTCGAAGGGTCACGAGGAACAGCAGCACCCAGACAGTGTCAGACAAGA GCACGCAGACGGTTCTGCCCTACACAGCCACTAGACAGAAAGCCAGGGGGAAAAACTAGGGGCCGGGGAGGGGGCCGGGGGCGGTGGGCA >In-frame_TMOD2_ENST00000539962_chr15_52075025_+_C15orf59_ENST00000569673_chr15_74032983_-_1842nt GTTGATCGCCGCGCTCGCCCCGGCCACGGCGCCGCCCCTGTTCTCCCGGCCCCGCTCCACCGGGGCTGACGGACTGACGGCCAGCACAGC CGGCTCCGGGATGAGCGCACGGACGGTATTCTGAAGTCTCAGGAAACTGGACCATTTAAATGTGCATGGCCCATGAGAAAGGCTTATAAG AAGCCATGGCACTCCCCTTTCAAAAAGAGCTGGAGAAATACAAGAACATTGATGAAGATGAGCTTCTTGGCAAACTCTCAGAAGAGGAAC TGAAACAGTTGGAAAATGTTCTAGATGACCTAGATCCTGAGGCTGGAGTGCCGTGGCAAGATCTCGGCTCACTGCAACCTCTGCCTCCCA GATTCAAGCGATTCTCCTACCTCAGCCTCCCAGAGTGCCATGCTGCCAGCTGGATTTCGACAGAAAGACCAGACACAGAAGGCAGCCACC GGCCCCTTTGACCGCGAGCACCTCCTCATGTACCTGGAGAAGGAGGCTTTGGAACAGAAAGACAGAGAGGACTTTGTGCCCTTCACTGGA GAAAAGAAAGGGAGAGTCTTTATCCCTAAAGAAAAGCCTATAGAAACTCGTAAAGAAGAAAAAGTGACCCTTGACCCAGAACTGGAAGAA GCTTTGGCCAGTGCCTCTGACACCGAACTCTATGATCTTGCAGCTGTCCTTGGAGTACACAATTTGCTCAACAATCCAAAGTTCGATGAA GAAACAGCCAACAATAAAGGTGGCAAAGGACCTGTCAGAAATGTTGTCAAAGGTGAAAAAGTAAAGCCAGTATTTGAGGAACCACCAAAT CCCACAAATGTGGAAATAAGCCTGCAGCAGATGAAAGCCAATGATCCTAGCTTGCAAGAAGTCAACCTCAACAACATTAAGAACATTCCA ATTCCAACCCTGAGGGAATTTGCAAAGGCTCTGGAGACCAACACTCACGTGAAGAAGTTCAGCCTGGCCGCAACTCGCAGCAATGACCCT GTGGCCATTGTGGTGAGCCAGATCGATAAGCTAACCTCGGACTTCGACTTTGAACTGGAGCCGGACGACTGGACCACGGCCACTGTGAGC AGCACCTCTAGCAGTGACAAGGCGGGCATGGGTGGCCCCTTTGACCTGGGCCACCTGGACTTCATGACAGCCGATATCCTCTCAGACAGC TGGGAGTTCTGCTCCTTCCTGGACGTCTCTACCCCCTCGGACTCCGTGGATGGTCCCGAGTCGACTCGGCCAGGGGCTGGCCCTGACTAC CGCCTCATGAATGGTGGCACGCCCATCCCCAATGGGCCACGAGTGGAGACCCCAGACTCCTCCAGTGAGGAGGCCTTTGGTGCTGGCCCC ACGGTGAAGAGCCAGCTGCCCCAGCGGACCCCAGGGACACGGGAGAGGGTGCGGTTCAGTGACAAAGTGCTCTACCATGCTCTGTGCTGT GACGATGAGGAGGGGGACGGTGAGCAGGAGGTGGAGGAGGAAGAAGTGGGCTTGCCCCCTGAGCCTGCCCATACAGAGGCCCATGCAGGC CCCCACAAGCCCTCCCCAGCCCCCTACAAGTCACGGCGCTCTCCACTGACCAGCCGCCACTCAGGCTCTACCTTGGCCCCTGAACAGACT CGAAGGGTCACGAGGAACAGCAGCACCCAGACAGTGTCAGACAAGAGCACGCAGACGGTTCTGCCCTACACAGCCACTAGACAGAAAGCC AGGGGGAAAAACTAGGGGCCGGGGAGGGGGCCGGGGGCGGTGGGCACATAGAGCTATAAATAAATATATATATATATATATATATATATA >In-frame_TMOD2_ENST00000539962_chr15_52075025_+_C15orf59_ENST00000379822_chr15_74032983_-_1831nt GTTGATCGCCGCGCTCGCCCCGGCCACGGCGCCGCCCCTGTTCTCCCGGCCCCGCTCCACCGGGGCTGACGGACTGACGGCCAGCACAGC CGGCTCCGGGATGAGCGCACGGACGGTATTCTGAAGTCTCAGGAAACTGGACCATTTAAATGTGCATGGCCCATGAGAAAGGCTTATAAG AAGCCATGGCACTCCCCTTTCAAAAAGAGCTGGAGAAATACAAGAACATTGATGAAGATGAGCTTCTTGGCAAACTCTCAGAAGAGGAAC TGAAACAGTTGGAAAATGTTCTAGATGACCTAGATCCTGAGGCTGGAGTGCCGTGGCAAGATCTCGGCTCACTGCAACCTCTGCCTCCCA GATTCAAGCGATTCTCCTACCTCAGCCTCCCAGAGTGCCATGCTGCCAGCTGGATTTCGACAGAAAGACCAGACACAGAAGGCAGCCACC GGCCCCTTTGACCGCGAGCACCTCCTCATGTACCTGGAGAAGGAGGCTTTGGAACAGAAAGACAGAGAGGACTTTGTGCCCTTCACTGGA GAAAAGAAAGGGAGAGTCTTTATCCCTAAAGAAAAGCCTATAGAAACTCGTAAAGAAGAAAAAGTGACCCTTGACCCAGAACTGGAAGAA GCTTTGGCCAGTGCCTCTGACACCGAACTCTATGATCTTGCAGCTGTCCTTGGAGTACACAATTTGCTCAACAATCCAAAGTTCGATGAA GAAACAGCCAACAATAAAGGTGGCAAAGGACCTGTCAGAAATGTTGTCAAAGGTGAAAAAGTAAAGCCAGTATTTGAGGAACCACCAAAT CCCACAAATGTGGAAATAAGCCTGCAGCAGATGAAAGCCAATGATCCTAGCTTGCAAGAAGTCAACCTCAACAACATTAAGAACATTCCA ATTCCAACCCTGAGGGAATTTGCAAAGGCTCTGGAGACCAACACTCACGTGAAGAAGTTCAGCCTGGCCGCAACTCGCAGCAATGACCCT GTGGCCATTGTGGTGAGCCAGATCGATAAGCTAACCTCGGACTTCGACTTTGAACTGGAGCCGGACGACTGGACCACGGCCACTGTGAGC AGCACCTCTAGCAGTGACAAGGCGGGCATGGGTGGCCCCTTTGACCTGGGCCACCTGGACTTCATGACAGCCGATATCCTCTCAGACAGC TGGGAGTTCTGCTCCTTCCTGGACGTCTCTACCCCCTCGGACTCCGTGGATGGTCCCGAGTCGACTCGGCCAGGGGCTGGCCCTGACTAC CGCCTCATGAATGGTGGCACGCCCATCCCCAATGGGCCACGAGTGGAGACCCCAGACTCCTCCAGTGAGGAGGCCTTTGGTGCTGGCCCC ACGGTGAAGAGCCAGCTGCCCCAGCGGACCCCAGGGACACGGGAGAGGGTGCGGTTCAGTGACAAAGTGCTCTACCATGCTCTGTGCTGT GACGATGAGGAGGGGGACGGTGAGCAGGAGGTGGAGGAGGAAGAAGTGGGCTTGCCCCCTGAGCCTGCCCATACAGAGGCCCATGCAGGC CCCCACAAGCCCTCCCCAGCCCCCTACAAGTCACGGCGCTCTCCACTGACCAGCCGCCACTCAGGCTCTACCTTGGCCCCTGAACAGACT CGAAGGGTCACGAGGAACAGCAGCACCCAGACAGTGTCAGACAAGAGCACGCAGACGGTTCTGCCCTACACAGCCACTAGACAGAAAGCC AGGGGGAAAAACTAGGGGCCGGGGAGGGGGCCGGGGGCGGTGGGCACATAGAGCTATAAATAAATATATATATATATATATATATATATA 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FusionGenePPI for TMOD2_C15orf59 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| TMOD2 | APP, SF3B2, SAFB, SF3B3, ABCC1, PAN2, SHMT2, LUZP4, SLC25A41, GSN, SCIN, RRM2B, RBM18, PABPC3, PAM16, RUVBL2, SULT1C3, ATP6V1B2, ATP6V1E1, DHX9, VARS, LSP1, AVIL, MYO6, SSH1, PLEKHG6, DBN1, PARK7 | C15orf59 | PPP1CC |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for TMOD2_C15orf59 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for TMOD2_C15orf59 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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