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Fusion gene ID: 380 |
FusionGeneSummary for ACER3_PPME1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ACER3_PPME1 | Fusion gene ID: 380 | Hgene | Tgene | Gene symbol | ACER3 | PPME1 | Gene ID | 55331 | 51400 |
| Gene name | alkaline ceramidase 3 | protein phosphatase methylesterase 1 | |
| Synonyms | APHC|PHCA|PLDECO | PME-1 | |
| Cytomap | 11q13.5 | 11q13.4 | |
| Type of gene | protein-coding | protein-coding | |
| Description | alkaline ceramidase 3alkCDase 3alkaline CDase 3alkaline dihydroceramidase SB89alkaline phytoceramidasephytoceramidase, alkaline | protein phosphatase methylesterase 1testicular secretory protein Li 39 | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q9NUN7 | Q9Y570 | |
| Ensembl transtripts involved in fusion gene | ENST00000532485, ENST00000530182, ENST00000526597, ENST00000533873, ENST00000538157, ENST00000544113, | ENST00000328257, ENST00000398427, ENST00000542710, ENST00000543525, | |
| Fusion gene scores | * DoF score | 9 X 4 X 5=180 | 8 X 5 X 6=240 |
| # samples | 9 | 8 | |
| ** MAII score | log2(9/180*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/240*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ACER3 [Title/Abstract] AND PPME1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ACER3 | GO:0046512 | sphingosine biosynthetic process | 20068046 |
| Hgene | ACER3 | GO:0071602 | phytosphingosine biosynthetic process | 11356846|20068046 |
| Tgene | PPME1 | GO:0006482 | protein demethylation | 10318862 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LUAD | TCGA-05-5425-01A | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000532485 | ENST00000328257 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| In-frame | ENST00000532485 | ENST00000398427 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| 5CDS-intron | ENST00000532485 | ENST00000542710 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| 5CDS-intron | ENST00000532485 | ENST00000543525 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| 3UTR-3CDS | ENST00000530182 | ENST00000328257 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| 3UTR-3CDS | ENST00000530182 | ENST00000398427 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| 3UTR-intron | ENST00000530182 | ENST00000542710 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| 3UTR-intron | ENST00000530182 | ENST00000543525 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| intron-3CDS | ENST00000526597 | ENST00000328257 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| intron-3CDS | ENST00000526597 | ENST00000398427 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| intron-intron | ENST00000526597 | ENST00000542710 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| intron-intron | ENST00000526597 | ENST00000543525 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| In-frame | ENST00000533873 | ENST00000328257 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| In-frame | ENST00000533873 | ENST00000398427 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| 5CDS-intron | ENST00000533873 | ENST00000542710 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| 5CDS-intron | ENST00000533873 | ENST00000543525 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| In-frame | ENST00000538157 | ENST00000328257 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| In-frame | ENST00000538157 | ENST00000398427 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| 5CDS-intron | ENST00000538157 | ENST00000542710 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| 5CDS-intron | ENST00000538157 | ENST00000543525 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| intron-3CDS | ENST00000544113 | ENST00000328257 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| intron-3CDS | ENST00000544113 | ENST00000398427 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| intron-intron | ENST00000544113 | ENST00000542710 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
| intron-intron | ENST00000544113 | ENST00000543525 | ACER3 | chr11 | 76670075 | + | PPME1 | chr11 | 73933357 | + |
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FusionProtFeatures for ACER3_PPME1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ACER3 | PPME1 |
| Hydrolyzes only phytoceramide into phytosphingosine andfree fatty acid. Does not have reverse activity. | Demethylates proteins that have been reversiblycarboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA.Binding to PPP2CA displaces the manganese ion and inactivates theenzyme. {ECO:0000269|PubMed:10318862}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ACER3 | chr11:76670075 | chr11:73933357 | ENST00000532485 | + | 3 | 11 | 29_51 | 89 | 268 | Transmembrane | Helical |
| Hgene | ACER3 | chr11:76670075 | chr11:73933357 | ENST00000532485 | + | 3 | 11 | 63_84 | 89 | 268 | Transmembrane | Helical |
| Tgene | >PPME1 | chr11:76670075 | chr11:73933357 | ENST00000328257 | + | 2 | 14 | 256_263 | 96 | 387 | Compositional bias | Note=Poly-Glu |
| Tgene | >PPME1 | chr11:76670075 | chr11:73933357 | ENST00000543525 | + | 0 | 8 | 256_263 | -45 | 200 | Compositional bias | Note=Poly-Glu |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ACER3 | chr11:76670075 | chr11:73933357 | ENST00000532485 | + | 3 | 11 | 118_137 | 89 | 268 | Transmembrane | Helical |
| Hgene | >ACER3 | chr11:76670075 | chr11:73933357 | ENST00000532485 | + | 3 | 11 | 147_169 | 89 | 268 | Transmembrane | Helical |
| Hgene | >ACER3 | chr11:76670075 | chr11:73933357 | ENST00000532485 | + | 3 | 11 | 174_196 | 89 | 268 | Transmembrane | Helical |
| Hgene | >ACER3 | chr11:76670075 | chr11:73933357 | ENST00000532485 | + | 3 | 11 | 216_238 | 89 | 268 | Transmembrane | Helical |
| Hgene | >ACER3 | chr11:76670075 | chr11:73933357 | ENST00000532485 | + | 3 | 11 | 94_111 | 89 | 268 | Transmembrane | Helical |
| Hgene | >ACER3 | chr11:76670075 | chr11:73933357 | ENST00000544113 | + | 1 | 6 | 118_137 | 0 | 135 | Transmembrane | Helical |
| Hgene | >ACER3 | chr11:76670075 | chr11:73933357 | ENST00000544113 | + | 1 | 6 | 147_169 | 0 | 135 | Transmembrane | Helical |
| Hgene | >ACER3 | chr11:76670075 | chr11:73933357 | ENST00000544113 | + | 1 | 6 | 174_196 | 0 | 135 | Transmembrane | Helical |
| Hgene | >ACER3 | chr11:76670075 | chr11:73933357 | ENST00000544113 | + | 1 | 6 | 216_238 | 0 | 135 | Transmembrane | Helical |
| Hgene | >ACER3 | chr11:76670075 | chr11:73933357 | ENST00000544113 | + | 1 | 6 | 29_51 | 0 | 135 | Transmembrane | Helical |
| Hgene | >ACER3 | chr11:76670075 | chr11:73933357 | ENST00000544113 | + | 1 | 6 | 63_84 | 0 | 135 | Transmembrane | Helical |
| Hgene | >ACER3 | chr11:76670075 | chr11:73933357 | ENST00000544113 | + | 1 | 6 | 94_111 | 0 | 135 | Transmembrane | Helical |
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FusionGeneSequence for ACER3_PPME1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ACER3_ENST00000532485_chr11_76670075_+_PPME1_ENST00000328257_chr11_73933357_+_380aa MAPAADREGYWGPTTSTLDWCEENYSVTWYIAEFWNTVSNLIMIIPPMFGAVQSVRDGLEKRYIASYLALTVVGMGSWCFHMTLKYEMQA AIISRVQCRIVALDLRSHGETKVKNPEDLSAETMAKDVGNVVEAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMIDVVEGTA MDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDM ETKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVAEAVATFL >In-frame_ACER3_ENST00000532485_chr11_76670075_+_PPME1_ENST00000398427_chr11_73933357_+_394aa MAPAADREGYWGPTTSTLDWCEENYSVTWYIAEFWNTVSNLIMIIPPMFGAVQSVRDGLEKRYIASYLALTVVGMGSWCFHMTLKYEMQA AIISRVQCRIVALDLRSHGETKVKNPEDLSAETMAKDVGNVVEAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMIDVVEGTA MDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDM EGLPSETQNLLLFLQTKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHE >In-frame_ACER3_ENST00000533873_chr11_76670075_+_PPME1_ENST00000328257_chr11_73933357_+_343aa MAPAADREGYWGPTTSTLDWCEENYSVTWYIAEFLVGMGSWCFHMTLKYEMQAAIISRVQCRIVALDLRSHGETKVKNPEDLSAETMAKD VGNVVEAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNL ESARVSMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDMETKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPI >In-frame_ACER3_ENST00000533873_chr11_76670075_+_PPME1_ENST00000398427_chr11_73933357_+_357aa MAPAADREGYWGPTTSTLDWCEENYSVTWYIAEFLVGMGSWCFHMTLKYEMQAAIISRVQCRIVALDLRSHGETKVKNPEDLSAETMAKD VGNVVEAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNL ESARVSMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDMEGLPSETQNLLLFLQTKKDHPYTWRIELAKTEKYWDG >In-frame_ACER3_ENST00000538157_chr11_76670075_+_PPME1_ENST00000328257_chr11_73933357_+_338aa MIIPPMFGAVQSVRDGLEKRYIASYLALTVVGMGSWCFHMTLKYEMQAAIISRVQCRIVALDLRSHGETKVKNPEDLSAETMAKDVGNVV EAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARV SMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDMETKKDHPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLL >In-frame_ACER3_ENST00000538157_chr11_76670075_+_PPME1_ENST00000398427_chr11_73933357_+_352aa MIIPPMFGAVQSVRDGLEKRYIASYLALTVVGMGSWCFHMTLKYEMQAAIISRVQCRIVALDLRSHGETKVKNPEDLSAETMAKDVGNVV EAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARV SMVGQVKQCEGITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDMEGLPSETQNLLLFLQTKKDHPYTWRIELAKTEKYWDGWFRGL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ACER3_ENST00000532485_chr11_76670075_+_PPME1_ENST00000328257_chr11_73933357_+_1140nt ATGGCTCCGGCCGCGGACCGAGAGGGCTACTGGGGCCCCACGACCTCCACGCTGGACTGGTGCGAGGAGAACTACTCCGTGACCTGGTAC ATCGCCGAGTTCTGGAATACAGTGAGTAACCTGATCATGATTATACCTCCAATGTTCGGTGCAGTTCAGAGTGTTAGAGACGGTCTGGAA AAGCGGTACATTGCTTCTTATTTAGCACTCACAGTGGTAGGAATGGGATCCTGGTGCTTCCACATGACTCTGAAATATGAAATGCAGGCA GCGATTATTAGTAGAGTTCAGTGTAGGATTGTAGCTTTGGATCTGCGAAGTCATGGTGAAACAAAGGTCAAGAATCCTGAAGATCTGTCT GCAGAAACAATGGCAAAAGACGTTGGCAATGTGGTTGAAGCCATGTATGGGGACCTTCCTCCTCCAATTATGCTGATTGGACATAGCATG GGTGGTGCTATTGCAGTCCACACAGCATCATCCAACCTGGTACCAAGCCTCTTGGGTCTGTGCATGATTGATGTTGTAGAAGGTACAGCT ATGGATGCACTTAATAGCATGCAGAATTTCTTACGGGGTCGTCCTAAAACCTTCAAGTCTCTGGAGAATGCTATTGAATGGAGTGTGAAG AGTGGCCAGATTCGAAATCTGGAGTCTGCCCGTGTCTCAATGGTTGGCCAAGTCAAACAGTGTGAAGGAATTACAAGTCCAGAAGGCTCA AAATCTATAGTGGAAGGAATCATAGAGGAAGAAGAAGAAGATGAGGAAGGAAGTGAGTCTATAAGCAAGAGGAAAAAGGAAGATGACATG GAGACCAAGAAAGACCATCCATACACCTGGAGAATTGAACTGGCAAAAACAGAAAAATACTGGGACGGCTGGTTCCGAGGCTTATCCAAT CTCTTTCTTAGTTGTCCCATTCCTAAATTGCTGCTCTTGGCTGGTGTTGATAGATTGGATAAAGATCTGACCATTGGCCAGATGCAAGGG AAGTTCCAGATGCAGGTCCTACCCCAGTGTGGCCATGCAGTCCATGAGGATGCCCCTGACAAGGTAGCTGAAGCTGTTGCCACTTTCCTG >In-frame_ACER3_ENST00000532485_chr11_76670075_+_PPME1_ENST00000398427_chr11_73933357_+_1182nt ATGGCTCCGGCCGCGGACCGAGAGGGCTACTGGGGCCCCACGACCTCCACGCTGGACTGGTGCGAGGAGAACTACTCCGTGACCTGGTAC ATCGCCGAGTTCTGGAATACAGTGAGTAACCTGATCATGATTATACCTCCAATGTTCGGTGCAGTTCAGAGTGTTAGAGACGGTCTGGAA AAGCGGTACATTGCTTCTTATTTAGCACTCACAGTGGTAGGAATGGGATCCTGGTGCTTCCACATGACTCTGAAATATGAAATGCAGGCA GCGATTATTAGTAGAGTTCAGTGTAGGATTGTAGCTTTGGATCTGCGAAGTCATGGTGAAACAAAGGTCAAGAATCCTGAAGATCTGTCT GCAGAAACAATGGCAAAAGACGTTGGCAATGTGGTTGAAGCCATGTATGGGGACCTTCCTCCTCCAATTATGCTGATTGGACATAGCATG GGTGGTGCTATTGCAGTCCACACAGCATCATCCAACCTGGTACCAAGCCTCTTGGGTCTGTGCATGATTGATGTTGTAGAAGGTACAGCT ATGGATGCACTTAATAGCATGCAGAATTTCTTACGGGGTCGTCCTAAAACCTTCAAGTCTCTGGAGAATGCTATTGAATGGAGTGTGAAG AGTGGCCAGATTCGAAATCTGGAGTCTGCCCGTGTCTCAATGGTTGGCCAAGTCAAACAGTGTGAAGGAATTACAAGTCCAGAAGGCTCA AAATCTATAGTGGAAGGAATCATAGAGGAAGAAGAAGAAGATGAGGAAGGAAGTGAGTCTATAAGCAAGAGGAAAAAGGAAGATGACATG GAGGGGTTGCCCTCGGAGACTCAGAACTTGCTCTTATTCCTCCAGACCAAGAAAGACCATCCATACACCTGGAGAATTGAACTGGCAAAA ACAGAAAAATACTGGGACGGCTGGTTCCGAGGCTTATCCAATCTCTTTCTTAGTTGTCCCATTCCTAAATTGCTGCTCTTGGCTGGTGTT GATAGATTGGATAAAGATCTGACCATTGGCCAGATGCAAGGGAAGTTCCAGATGCAGGTCCTACCCCAGTGTGGCCATGCAGTCCATGAG GATGCCCCTGACAAGGTAGCTGAAGCTGTTGCCACTTTCCTGATCCGGCACAGGTTTGCAGAACCCATCGGTGGATTCCAGTGTGTGTTT >In-frame_ACER3_ENST00000533873_chr11_76670075_+_PPME1_ENST00000328257_chr11_73933357_+_1029nt ATGGCTCCGGCCGCGGACCGAGAGGGCTACTGGGGCCCCACGACCTCCACGCTGGACTGGTGCGAGGAGAACTACTCCGTGACCTGGTAC ATCGCCGAGTTCTTGGTAGGAATGGGATCCTGGTGCTTCCACATGACTCTGAAATATGAAATGCAGGCAGCGATTATTAGTAGAGTTCAG TGTAGGATTGTAGCTTTGGATCTGCGAAGTCATGGTGAAACAAAGGTCAAGAATCCTGAAGATCTGTCTGCAGAAACAATGGCAAAAGAC GTTGGCAATGTGGTTGAAGCCATGTATGGGGACCTTCCTCCTCCAATTATGCTGATTGGACATAGCATGGGTGGTGCTATTGCAGTCCAC ACAGCATCATCCAACCTGGTACCAAGCCTCTTGGGTCTGTGCATGATTGATGTTGTAGAAGGTACAGCTATGGATGCACTTAATAGCATG CAGAATTTCTTACGGGGTCGTCCTAAAACCTTCAAGTCTCTGGAGAATGCTATTGAATGGAGTGTGAAGAGTGGCCAGATTCGAAATCTG GAGTCTGCCCGTGTCTCAATGGTTGGCCAAGTCAAACAGTGTGAAGGAATTACAAGTCCAGAAGGCTCAAAATCTATAGTGGAAGGAATC ATAGAGGAAGAAGAAGAAGATGAGGAAGGAAGTGAGTCTATAAGCAAGAGGAAAAAGGAAGATGACATGGAGACCAAGAAAGACCATCCA TACACCTGGAGAATTGAACTGGCAAAAACAGAAAAATACTGGGACGGCTGGTTCCGAGGCTTATCCAATCTCTTTCTTAGTTGTCCCATT CCTAAATTGCTGCTCTTGGCTGGTGTTGATAGATTGGATAAAGATCTGACCATTGGCCAGATGCAAGGGAAGTTCCAGATGCAGGTCCTA CCCCAGTGTGGCCATGCAGTCCATGAGGATGCCCCTGACAAGGTAGCTGAAGCTGTTGCCACTTTCCTGATCCGGCACAGGTTTGCAGAA >In-frame_ACER3_ENST00000533873_chr11_76670075_+_PPME1_ENST00000398427_chr11_73933357_+_1071nt ATGGCTCCGGCCGCGGACCGAGAGGGCTACTGGGGCCCCACGACCTCCACGCTGGACTGGTGCGAGGAGAACTACTCCGTGACCTGGTAC ATCGCCGAGTTCTTGGTAGGAATGGGATCCTGGTGCTTCCACATGACTCTGAAATATGAAATGCAGGCAGCGATTATTAGTAGAGTTCAG TGTAGGATTGTAGCTTTGGATCTGCGAAGTCATGGTGAAACAAAGGTCAAGAATCCTGAAGATCTGTCTGCAGAAACAATGGCAAAAGAC GTTGGCAATGTGGTTGAAGCCATGTATGGGGACCTTCCTCCTCCAATTATGCTGATTGGACATAGCATGGGTGGTGCTATTGCAGTCCAC ACAGCATCATCCAACCTGGTACCAAGCCTCTTGGGTCTGTGCATGATTGATGTTGTAGAAGGTACAGCTATGGATGCACTTAATAGCATG CAGAATTTCTTACGGGGTCGTCCTAAAACCTTCAAGTCTCTGGAGAATGCTATTGAATGGAGTGTGAAGAGTGGCCAGATTCGAAATCTG GAGTCTGCCCGTGTCTCAATGGTTGGCCAAGTCAAACAGTGTGAAGGAATTACAAGTCCAGAAGGCTCAAAATCTATAGTGGAAGGAATC ATAGAGGAAGAAGAAGAAGATGAGGAAGGAAGTGAGTCTATAAGCAAGAGGAAAAAGGAAGATGACATGGAGGGGTTGCCCTCGGAGACT CAGAACTTGCTCTTATTCCTCCAGACCAAGAAAGACCATCCATACACCTGGAGAATTGAACTGGCAAAAACAGAAAAATACTGGGACGGC TGGTTCCGAGGCTTATCCAATCTCTTTCTTAGTTGTCCCATTCCTAAATTGCTGCTCTTGGCTGGTGTTGATAGATTGGATAAAGATCTG ACCATTGGCCAGATGCAAGGGAAGTTCCAGATGCAGGTCCTACCCCAGTGTGGCCATGCAGTCCATGAGGATGCCCCTGACAAGGTAGCT >In-frame_ACER3_ENST00000538157_chr11_76670075_+_PPME1_ENST00000328257_chr11_73933357_+_1014nt ATGATTATACCTCCAATGTTCGGTGCAGTTCAGAGTGTTAGAGACGGTCTGGAAAAGCGGTACATTGCTTCTTATTTAGCACTCACAGTG GTAGGAATGGGATCCTGGTGCTTCCACATGACTCTGAAATATGAAATGCAGGCAGCGATTATTAGTAGAGTTCAGTGTAGGATTGTAGCT TTGGATCTGCGAAGTCATGGTGAAACAAAGGTCAAGAATCCTGAAGATCTGTCTGCAGAAACAATGGCAAAAGACGTTGGCAATGTGGTT GAAGCCATGTATGGGGACCTTCCTCCTCCAATTATGCTGATTGGACATAGCATGGGTGGTGCTATTGCAGTCCACACAGCATCATCCAAC CTGGTACCAAGCCTCTTGGGTCTGTGCATGATTGATGTTGTAGAAGGTACAGCTATGGATGCACTTAATAGCATGCAGAATTTCTTACGG GGTCGTCCTAAAACCTTCAAGTCTCTGGAGAATGCTATTGAATGGAGTGTGAAGAGTGGCCAGATTCGAAATCTGGAGTCTGCCCGTGTC TCAATGGTTGGCCAAGTCAAACAGTGTGAAGGAATTACAAGTCCAGAAGGCTCAAAATCTATAGTGGAAGGAATCATAGAGGAAGAAGAA GAAGATGAGGAAGGAAGTGAGTCTATAAGCAAGAGGAAAAAGGAAGATGACATGGAGACCAAGAAAGACCATCCATACACCTGGAGAATT GAACTGGCAAAAACAGAAAAATACTGGGACGGCTGGTTCCGAGGCTTATCCAATCTCTTTCTTAGTTGTCCCATTCCTAAATTGCTGCTC TTGGCTGGTGTTGATAGATTGGATAAAGATCTGACCATTGGCCAGATGCAAGGGAAGTTCCAGATGCAGGTCCTACCCCAGTGTGGCCAT GCAGTCCATGAGGATGCCCCTGACAAGGTAGCTGAAGCTGTTGCCACTTTCCTGATCCGGCACAGGTTTGCAGAACCCATCGGTGGATTC >In-frame_ACER3_ENST00000538157_chr11_76670075_+_PPME1_ENST00000398427_chr11_73933357_+_1056nt ATGATTATACCTCCAATGTTCGGTGCAGTTCAGAGTGTTAGAGACGGTCTGGAAAAGCGGTACATTGCTTCTTATTTAGCACTCACAGTG GTAGGAATGGGATCCTGGTGCTTCCACATGACTCTGAAATATGAAATGCAGGCAGCGATTATTAGTAGAGTTCAGTGTAGGATTGTAGCT TTGGATCTGCGAAGTCATGGTGAAACAAAGGTCAAGAATCCTGAAGATCTGTCTGCAGAAACAATGGCAAAAGACGTTGGCAATGTGGTT GAAGCCATGTATGGGGACCTTCCTCCTCCAATTATGCTGATTGGACATAGCATGGGTGGTGCTATTGCAGTCCACACAGCATCATCCAAC CTGGTACCAAGCCTCTTGGGTCTGTGCATGATTGATGTTGTAGAAGGTACAGCTATGGATGCACTTAATAGCATGCAGAATTTCTTACGG GGTCGTCCTAAAACCTTCAAGTCTCTGGAGAATGCTATTGAATGGAGTGTGAAGAGTGGCCAGATTCGAAATCTGGAGTCTGCCCGTGTC TCAATGGTTGGCCAAGTCAAACAGTGTGAAGGAATTACAAGTCCAGAAGGCTCAAAATCTATAGTGGAAGGAATCATAGAGGAAGAAGAA GAAGATGAGGAAGGAAGTGAGTCTATAAGCAAGAGGAAAAAGGAAGATGACATGGAGGGGTTGCCCTCGGAGACTCAGAACTTGCTCTTA TTCCTCCAGACCAAGAAAGACCATCCATACACCTGGAGAATTGAACTGGCAAAAACAGAAAAATACTGGGACGGCTGGTTCCGAGGCTTA TCCAATCTCTTTCTTAGTTGTCCCATTCCTAAATTGCTGCTCTTGGCTGGTGTTGATAGATTGGATAAAGATCTGACCATTGGCCAGATG CAAGGGAAGTTCCAGATGCAGGTCCTACCCCAGTGTGGCCATGCAGTCCATGAGGATGCCCCTGACAAGGTAGCTGAAGCTGTTGCCACT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ACER3_ENST00000532485_chr11_76670075_+_PPME1_ENST00000328257_chr11_73933357_+_2437nt GGGCGGGGCGCGAGCGAGCGCGCGGGCTGGGCCGGAGCCGGCCTGGTCGCCAGCCTAACCCGGCACAGTGAGCGGAGCGCCTGGGCGGCG GCGGCGGCGGCGTGATGGCTCCGGCCGCGGACCGAGAGGGCTACTGGGGCCCCACGACCTCCACGCTGGACTGGTGCGAGGAGAACTACT CCGTGACCTGGTACATCGCCGAGTTCTGGAATACAGTGAGTAACCTGATCATGATTATACCTCCAATGTTCGGTGCAGTTCAGAGTGTTA GAGACGGTCTGGAAAAGCGGTACATTGCTTCTTATTTAGCACTCACAGTGGTAGGAATGGGATCCTGGTGCTTCCACATGACTCTGAAAT ATGAAATGCAGGCAGCGATTATTAGTAGAGTTCAGTGTAGGATTGTAGCTTTGGATCTGCGAAGTCATGGTGAAACAAAGGTCAAGAATC CTGAAGATCTGTCTGCAGAAACAATGGCAAAAGACGTTGGCAATGTGGTTGAAGCCATGTATGGGGACCTTCCTCCTCCAATTATGCTGA TTGGACATAGCATGGGTGGTGCTATTGCAGTCCACACAGCATCATCCAACCTGGTACCAAGCCTCTTGGGTCTGTGCATGATTGATGTTG TAGAAGGTACAGCTATGGATGCACTTAATAGCATGCAGAATTTCTTACGGGGTCGTCCTAAAACCTTCAAGTCTCTGGAGAATGCTATTG AATGGAGTGTGAAGAGTGGCCAGATTCGAAATCTGGAGTCTGCCCGTGTCTCAATGGTTGGCCAAGTCAAACAGTGTGAAGGAATTACAA GTCCAGAAGGCTCAAAATCTATAGTGGAAGGAATCATAGAGGAAGAAGAAGAAGATGAGGAAGGAAGTGAGTCTATAAGCAAGAGGAAAA AGGAAGATGACATGGAGACCAAGAAAGACCATCCATACACCTGGAGAATTGAACTGGCAAAAACAGAAAAATACTGGGACGGCTGGTTCC GAGGCTTATCCAATCTCTTTCTTAGTTGTCCCATTCCTAAATTGCTGCTCTTGGCTGGTGTTGATAGATTGGATAAAGATCTGACCATTG GCCAGATGCAAGGGAAGTTCCAGATGCAGGTCCTACCCCAGTGTGGCCATGCAGTCCATGAGGATGCCCCTGACAAGGTAGCTGAAGCTG TTGCCACTTTCCTGATCCGGCACAGGTTTGCAGAACCCATCGGTGGATTCCAGTGTGTGTTTCCTGGCTGTTAGTGACCTGCTGTCCACC CCTCCTCAACATCGAGCTCTGTTGTAAATACGTCGCACCAGAGGCCACTGTGATGCCACTGTCTCCTCTCCATCCCGCCCAGCCATGTGA CACTGGCTCCCGGTAGACGGGCACCCCGAGATGTACCAACCTTTTCATGTATTCTGCCAAAAGCATTGTTTTCCAGGGCCCTTGACCAAC ATCGGCTTCCCCAGTCCAGGGCTCCCCTGCTCCTTTCCCTTCCCTGTACTGGGGTAGCTCCTGCCTGCTCTCCCTGCGTTGCCTAGGGTA AAGCCTCCAGATTTGCCATACTGAGCCCCTCTTCCTAGCATCAGGCGATACATCTGAGTTCAAATGTCTTCCCAGGCTCAGGGACCTCCA TTCCTTGAGATTGTCTTGGCATGGCCCAGCCCTGCCTCATGGGATGGACAATGCATGGGGTGGTCTTTATTTTTCCCTTTCAAATAAAAC ACTAGTCAGGTACCGTTTTATCCCAGTCGTACTCTTCCAGGTTTGGAAGACCCAGAGAGGCCAAGATCCCATCCTTAGCCATAGCGAGCG GTGGTGGTGGATAGCATCACAAGAAACGAGCCTGAAAATCAGGTCCAGCCGGTCCAAGCACATGGCCTCCCATCTGGGAGAGCCCACTGT CCCACTCCCACATGTCTGGGCACCTGCCCTGGGCTGAGGCCAGGCTGCTCCAGGGGCCTCCTGCGCCCTCACCTGCCACAGAGCAACCCA GGTTAAATACAGCCCATGCACAAAGCCACAGGCCAAAGCCTATGGAATTGTTTTTAATCATCAAATTTAACCATTTTCATAACTGGTTCC TGGAGGTGTGCAGTGCCCCCTTGCCTCTTCAAACCTACAGCTTCTCTTTGCCATTTGTGGATTTCACATCACTCCACACAGAAACATTAC AGCCTGGCATCCCCAGTCTTTGCCTTCTTCCAGCTGCCTCGACACAGCACTGTGGCCTGTCCCTATTGCCCAGGCACGCCATTTCCAAGG GCAGGAAGGGGCAGTGTCCTGAAGCCCATCTTTTCTGTGACTGTCTTAGGTGATGTGTAGCCCCCTCCACCTTTCCACTCAACAACCTCC CACCCCTGTCCTGCTGCATGGTCCGGAGTCTGGGACCTACTTTGTTTTTTGTTATTTATGACCTTGTTTAAAGAAAATAAATATCTCCCA >In-frame_ACER3_ENST00000532485_chr11_76670075_+_PPME1_ENST00000398427_chr11_73933357_+_2479nt GGGCGGGGCGCGAGCGAGCGCGCGGGCTGGGCCGGAGCCGGCCTGGTCGCCAGCCTAACCCGGCACAGTGAGCGGAGCGCCTGGGCGGCG GCGGCGGCGGCGTGATGGCTCCGGCCGCGGACCGAGAGGGCTACTGGGGCCCCACGACCTCCACGCTGGACTGGTGCGAGGAGAACTACT CCGTGACCTGGTACATCGCCGAGTTCTGGAATACAGTGAGTAACCTGATCATGATTATACCTCCAATGTTCGGTGCAGTTCAGAGTGTTA GAGACGGTCTGGAAAAGCGGTACATTGCTTCTTATTTAGCACTCACAGTGGTAGGAATGGGATCCTGGTGCTTCCACATGACTCTGAAAT ATGAAATGCAGGCAGCGATTATTAGTAGAGTTCAGTGTAGGATTGTAGCTTTGGATCTGCGAAGTCATGGTGAAACAAAGGTCAAGAATC CTGAAGATCTGTCTGCAGAAACAATGGCAAAAGACGTTGGCAATGTGGTTGAAGCCATGTATGGGGACCTTCCTCCTCCAATTATGCTGA TTGGACATAGCATGGGTGGTGCTATTGCAGTCCACACAGCATCATCCAACCTGGTACCAAGCCTCTTGGGTCTGTGCATGATTGATGTTG TAGAAGGTACAGCTATGGATGCACTTAATAGCATGCAGAATTTCTTACGGGGTCGTCCTAAAACCTTCAAGTCTCTGGAGAATGCTATTG AATGGAGTGTGAAGAGTGGCCAGATTCGAAATCTGGAGTCTGCCCGTGTCTCAATGGTTGGCCAAGTCAAACAGTGTGAAGGAATTACAA GTCCAGAAGGCTCAAAATCTATAGTGGAAGGAATCATAGAGGAAGAAGAAGAAGATGAGGAAGGAAGTGAGTCTATAAGCAAGAGGAAAA AGGAAGATGACATGGAGGGGTTGCCCTCGGAGACTCAGAACTTGCTCTTATTCCTCCAGACCAAGAAAGACCATCCATACACCTGGAGAA TTGAACTGGCAAAAACAGAAAAATACTGGGACGGCTGGTTCCGAGGCTTATCCAATCTCTTTCTTAGTTGTCCCATTCCTAAATTGCTGC TCTTGGCTGGTGTTGATAGATTGGATAAAGATCTGACCATTGGCCAGATGCAAGGGAAGTTCCAGATGCAGGTCCTACCCCAGTGTGGCC ATGCAGTCCATGAGGATGCCCCTGACAAGGTAGCTGAAGCTGTTGCCACTTTCCTGATCCGGCACAGGTTTGCAGAACCCATCGGTGGAT TCCAGTGTGTGTTTCCTGGCTGTTAGTGACCTGCTGTCCACCCCTCCTCAACATCGAGCTCTGTTGTAAATACGTCGCACCAGAGGCCAC TGTGATGCCACTGTCTCCTCTCCATCCCGCCCAGCCATGTGACACTGGCTCCCGGTAGACGGGCACCCCGAGATGTACCAACCTTTTCAT GTATTCTGCCAAAAGCATTGTTTTCCAGGGCCCTTGACCAACATCGGCTTCCCCAGTCCAGGGCTCCCCTGCTCCTTTCCCTTCCCTGTA CTGGGGTAGCTCCTGCCTGCTCTCCCTGCGTTGCCTAGGGTAAAGCCTCCAGATTTGCCATACTGAGCCCCTCTTCCTAGCATCAGGCGA TACATCTGAGTTCAAATGTCTTCCCAGGCTCAGGGACCTCCATTCCTTGAGATTGTCTTGGCATGGCCCAGCCCTGCCTCATGGGATGGA CAATGCATGGGGTGGTCTTTATTTTTCCCTTTCAAATAAAACACTAGTCAGGTACCGTTTTATCCCAGTCGTACTCTTCCAGGTTTGGAA GACCCAGAGAGGCCAAGATCCCATCCTTAGCCATAGCGAGCGGTGGTGGTGGATAGCATCACAAGAAACGAGCCTGAAAATCAGGTCCAG CCGGTCCAAGCACATGGCCTCCCATCTGGGAGAGCCCACTGTCCCACTCCCACATGTCTGGGCACCTGCCCTGGGCTGAGGCCAGGCTGC TCCAGGGGCCTCCTGCGCCCTCACCTGCCACAGAGCAACCCAGGTTAAATACAGCCCATGCACAAAGCCACAGGCCAAAGCCTATGGAAT TGTTTTTAATCATCAAATTTAACCATTTTCATAACTGGTTCCTGGAGGTGTGCAGTGCCCCCTTGCCTCTTCAAACCTACAGCTTCTCTT TGCCATTTGTGGATTTCACATCACTCCACACAGAAACATTACAGCCTGGCATCCCCAGTCTTTGCCTTCTTCCAGCTGCCTCGACACAGC ACTGTGGCCTGTCCCTATTGCCCAGGCACGCCATTTCCAAGGGCAGGAAGGGGCAGTGTCCTGAAGCCCATCTTTTCTGTGACTGTCTTA GGTGATGTGTAGCCCCCTCCACCTTTCCACTCAACAACCTCCCACCCCTGTCCTGCTGCATGGTCCGGAGTCTGGGACCTACTTTGTTTT >In-frame_ACER3_ENST00000533873_chr11_76670075_+_PPME1_ENST00000328257_chr11_73933357_+_2257nt GAGCGGAGCGCCTGGGCGGCGGCGGCGGCGGCGTGATGGCTCCGGCCGCGGACCGAGAGGGCTACTGGGGCCCCACGACCTCCACGCTGG ACTGGTGCGAGGAGAACTACTCCGTGACCTGGTACATCGCCGAGTTCTTGGTAGGAATGGGATCCTGGTGCTTCCACATGACTCTGAAAT ATGAAATGCAGGCAGCGATTATTAGTAGAGTTCAGTGTAGGATTGTAGCTTTGGATCTGCGAAGTCATGGTGAAACAAAGGTCAAGAATC CTGAAGATCTGTCTGCAGAAACAATGGCAAAAGACGTTGGCAATGTGGTTGAAGCCATGTATGGGGACCTTCCTCCTCCAATTATGCTGA TTGGACATAGCATGGGTGGTGCTATTGCAGTCCACACAGCATCATCCAACCTGGTACCAAGCCTCTTGGGTCTGTGCATGATTGATGTTG TAGAAGGTACAGCTATGGATGCACTTAATAGCATGCAGAATTTCTTACGGGGTCGTCCTAAAACCTTCAAGTCTCTGGAGAATGCTATTG AATGGAGTGTGAAGAGTGGCCAGATTCGAAATCTGGAGTCTGCCCGTGTCTCAATGGTTGGCCAAGTCAAACAGTGTGAAGGAATTACAA GTCCAGAAGGCTCAAAATCTATAGTGGAAGGAATCATAGAGGAAGAAGAAGAAGATGAGGAAGGAAGTGAGTCTATAAGCAAGAGGAAAA AGGAAGATGACATGGAGACCAAGAAAGACCATCCATACACCTGGAGAATTGAACTGGCAAAAACAGAAAAATACTGGGACGGCTGGTTCC GAGGCTTATCCAATCTCTTTCTTAGTTGTCCCATTCCTAAATTGCTGCTCTTGGCTGGTGTTGATAGATTGGATAAAGATCTGACCATTG GCCAGATGCAAGGGAAGTTCCAGATGCAGGTCCTACCCCAGTGTGGCCATGCAGTCCATGAGGATGCCCCTGACAAGGTAGCTGAAGCTG TTGCCACTTTCCTGATCCGGCACAGGTTTGCAGAACCCATCGGTGGATTCCAGTGTGTGTTTCCTGGCTGTTAGTGACCTGCTGTCCACC CCTCCTCAACATCGAGCTCTGTTGTAAATACGTCGCACCAGAGGCCACTGTGATGCCACTGTCTCCTCTCCATCCCGCCCAGCCATGTGA CACTGGCTCCCGGTAGACGGGCACCCCGAGATGTACCAACCTTTTCATGTATTCTGCCAAAAGCATTGTTTTCCAGGGCCCTTGACCAAC ATCGGCTTCCCCAGTCCAGGGCTCCCCTGCTCCTTTCCCTTCCCTGTACTGGGGTAGCTCCTGCCTGCTCTCCCTGCGTTGCCTAGGGTA AAGCCTCCAGATTTGCCATACTGAGCCCCTCTTCCTAGCATCAGGCGATACATCTGAGTTCAAATGTCTTCCCAGGCTCAGGGACCTCCA TTCCTTGAGATTGTCTTGGCATGGCCCAGCCCTGCCTCATGGGATGGACAATGCATGGGGTGGTCTTTATTTTTCCCTTTCAAATAAAAC ACTAGTCAGGTACCGTTTTATCCCAGTCGTACTCTTCCAGGTTTGGAAGACCCAGAGAGGCCAAGATCCCATCCTTAGCCATAGCGAGCG GTGGTGGTGGATAGCATCACAAGAAACGAGCCTGAAAATCAGGTCCAGCCGGTCCAAGCACATGGCCTCCCATCTGGGAGAGCCCACTGT CCCACTCCCACATGTCTGGGCACCTGCCCTGGGCTGAGGCCAGGCTGCTCCAGGGGCCTCCTGCGCCCTCACCTGCCACAGAGCAACCCA GGTTAAATACAGCCCATGCACAAAGCCACAGGCCAAAGCCTATGGAATTGTTTTTAATCATCAAATTTAACCATTTTCATAACTGGTTCC TGGAGGTGTGCAGTGCCCCCTTGCCTCTTCAAACCTACAGCTTCTCTTTGCCATTTGTGGATTTCACATCACTCCACACAGAAACATTAC AGCCTGGCATCCCCAGTCTTTGCCTTCTTCCAGCTGCCTCGACACAGCACTGTGGCCTGTCCCTATTGCCCAGGCACGCCATTTCCAAGG GCAGGAAGGGGCAGTGTCCTGAAGCCCATCTTTTCTGTGACTGTCTTAGGTGATGTGTAGCCCCCTCCACCTTTCCACTCAACAACCTCC CACCCCTGTCCTGCTGCATGGTCCGGAGTCTGGGACCTACTTTGTTTTTTGTTATTTATGACCTTGTTTAAAGAAAATAAATATCTCCCA >In-frame_ACER3_ENST00000533873_chr11_76670075_+_PPME1_ENST00000398427_chr11_73933357_+_2299nt GAGCGGAGCGCCTGGGCGGCGGCGGCGGCGGCGTGATGGCTCCGGCCGCGGACCGAGAGGGCTACTGGGGCCCCACGACCTCCACGCTGG ACTGGTGCGAGGAGAACTACTCCGTGACCTGGTACATCGCCGAGTTCTTGGTAGGAATGGGATCCTGGTGCTTCCACATGACTCTGAAAT ATGAAATGCAGGCAGCGATTATTAGTAGAGTTCAGTGTAGGATTGTAGCTTTGGATCTGCGAAGTCATGGTGAAACAAAGGTCAAGAATC CTGAAGATCTGTCTGCAGAAACAATGGCAAAAGACGTTGGCAATGTGGTTGAAGCCATGTATGGGGACCTTCCTCCTCCAATTATGCTGA TTGGACATAGCATGGGTGGTGCTATTGCAGTCCACACAGCATCATCCAACCTGGTACCAAGCCTCTTGGGTCTGTGCATGATTGATGTTG TAGAAGGTACAGCTATGGATGCACTTAATAGCATGCAGAATTTCTTACGGGGTCGTCCTAAAACCTTCAAGTCTCTGGAGAATGCTATTG AATGGAGTGTGAAGAGTGGCCAGATTCGAAATCTGGAGTCTGCCCGTGTCTCAATGGTTGGCCAAGTCAAACAGTGTGAAGGAATTACAA GTCCAGAAGGCTCAAAATCTATAGTGGAAGGAATCATAGAGGAAGAAGAAGAAGATGAGGAAGGAAGTGAGTCTATAAGCAAGAGGAAAA AGGAAGATGACATGGAGGGGTTGCCCTCGGAGACTCAGAACTTGCTCTTATTCCTCCAGACCAAGAAAGACCATCCATACACCTGGAGAA TTGAACTGGCAAAAACAGAAAAATACTGGGACGGCTGGTTCCGAGGCTTATCCAATCTCTTTCTTAGTTGTCCCATTCCTAAATTGCTGC TCTTGGCTGGTGTTGATAGATTGGATAAAGATCTGACCATTGGCCAGATGCAAGGGAAGTTCCAGATGCAGGTCCTACCCCAGTGTGGCC ATGCAGTCCATGAGGATGCCCCTGACAAGGTAGCTGAAGCTGTTGCCACTTTCCTGATCCGGCACAGGTTTGCAGAACCCATCGGTGGAT TCCAGTGTGTGTTTCCTGGCTGTTAGTGACCTGCTGTCCACCCCTCCTCAACATCGAGCTCTGTTGTAAATACGTCGCACCAGAGGCCAC TGTGATGCCACTGTCTCCTCTCCATCCCGCCCAGCCATGTGACACTGGCTCCCGGTAGACGGGCACCCCGAGATGTACCAACCTTTTCAT GTATTCTGCCAAAAGCATTGTTTTCCAGGGCCCTTGACCAACATCGGCTTCCCCAGTCCAGGGCTCCCCTGCTCCTTTCCCTTCCCTGTA CTGGGGTAGCTCCTGCCTGCTCTCCCTGCGTTGCCTAGGGTAAAGCCTCCAGATTTGCCATACTGAGCCCCTCTTCCTAGCATCAGGCGA TACATCTGAGTTCAAATGTCTTCCCAGGCTCAGGGACCTCCATTCCTTGAGATTGTCTTGGCATGGCCCAGCCCTGCCTCATGGGATGGA CAATGCATGGGGTGGTCTTTATTTTTCCCTTTCAAATAAAACACTAGTCAGGTACCGTTTTATCCCAGTCGTACTCTTCCAGGTTTGGAA GACCCAGAGAGGCCAAGATCCCATCCTTAGCCATAGCGAGCGGTGGTGGTGGATAGCATCACAAGAAACGAGCCTGAAAATCAGGTCCAG CCGGTCCAAGCACATGGCCTCCCATCTGGGAGAGCCCACTGTCCCACTCCCACATGTCTGGGCACCTGCCCTGGGCTGAGGCCAGGCTGC TCCAGGGGCCTCCTGCGCCCTCACCTGCCACAGAGCAACCCAGGTTAAATACAGCCCATGCACAAAGCCACAGGCCAAAGCCTATGGAAT TGTTTTTAATCATCAAATTTAACCATTTTCATAACTGGTTCCTGGAGGTGTGCAGTGCCCCCTTGCCTCTTCAAACCTACAGCTTCTCTT TGCCATTTGTGGATTTCACATCACTCCACACAGAAACATTACAGCCTGGCATCCCCAGTCTTTGCCTTCTTCCAGCTGCCTCGACACAGC ACTGTGGCCTGTCCCTATTGCCCAGGCACGCCATTTCCAAGGGCAGGAAGGGGCAGTGTCCTGAAGCCCATCTTTTCTGTGACTGTCTTA GGTGATGTGTAGCCCCCTCCACCTTTCCACTCAACAACCTCCCACCCCTGTCCTGCTGCATGGTCCGGAGTCTGGGACCTACTTTGTTTT >In-frame_ACER3_ENST00000538157_chr11_76670075_+_PPME1_ENST00000328257_chr11_73933357_+_2404nt AGCGGAGCGCCTGGGCGGCGGCGGCGGCGGCGTGATGGCTCCGGCCGCGGACCGAGAGGGCTACTGGGGCCCCACGACCTCCACGCTGGA CTGGTGCGAGGAGAACTACTCCGTGACCTGGTACATCGCCGAGTTCTGTTCCTTCCTACCATCCTCCCTGAAGAGCAACCTCAAGGAATA CAGTGAGTAACCTGATCATGATTATACCTCCAATGTTCGGTGCAGTTCAGAGTGTTAGAGACGGTCTGGAAAAGCGGTACATTGCTTCTT ATTTAGCACTCACAGTGGTAGGAATGGGATCCTGGTGCTTCCACATGACTCTGAAATATGAAATGCAGGCAGCGATTATTAGTAGAGTTC AGTGTAGGATTGTAGCTTTGGATCTGCGAAGTCATGGTGAAACAAAGGTCAAGAATCCTGAAGATCTGTCTGCAGAAACAATGGCAAAAG ACGTTGGCAATGTGGTTGAAGCCATGTATGGGGACCTTCCTCCTCCAATTATGCTGATTGGACATAGCATGGGTGGTGCTATTGCAGTCC ACACAGCATCATCCAACCTGGTACCAAGCCTCTTGGGTCTGTGCATGATTGATGTTGTAGAAGGTACAGCTATGGATGCACTTAATAGCA TGCAGAATTTCTTACGGGGTCGTCCTAAAACCTTCAAGTCTCTGGAGAATGCTATTGAATGGAGTGTGAAGAGTGGCCAGATTCGAAATC TGGAGTCTGCCCGTGTCTCAATGGTTGGCCAAGTCAAACAGTGTGAAGGAATTACAAGTCCAGAAGGCTCAAAATCTATAGTGGAAGGAA TCATAGAGGAAGAAGAAGAAGATGAGGAAGGAAGTGAGTCTATAAGCAAGAGGAAAAAGGAAGATGACATGGAGACCAAGAAAGACCATC CATACACCTGGAGAATTGAACTGGCAAAAACAGAAAAATACTGGGACGGCTGGTTCCGAGGCTTATCCAATCTCTTTCTTAGTTGTCCCA TTCCTAAATTGCTGCTCTTGGCTGGTGTTGATAGATTGGATAAAGATCTGACCATTGGCCAGATGCAAGGGAAGTTCCAGATGCAGGTCC TACCCCAGTGTGGCCATGCAGTCCATGAGGATGCCCCTGACAAGGTAGCTGAAGCTGTTGCCACTTTCCTGATCCGGCACAGGTTTGCAG AACCCATCGGTGGATTCCAGTGTGTGTTTCCTGGCTGTTAGTGACCTGCTGTCCACCCCTCCTCAACATCGAGCTCTGTTGTAAATACGT CGCACCAGAGGCCACTGTGATGCCACTGTCTCCTCTCCATCCCGCCCAGCCATGTGACACTGGCTCCCGGTAGACGGGCACCCCGAGATG TACCAACCTTTTCATGTATTCTGCCAAAAGCATTGTTTTCCAGGGCCCTTGACCAACATCGGCTTCCCCAGTCCAGGGCTCCCCTGCTCC TTTCCCTTCCCTGTACTGGGGTAGCTCCTGCCTGCTCTCCCTGCGTTGCCTAGGGTAAAGCCTCCAGATTTGCCATACTGAGCCCCTCTT CCTAGCATCAGGCGATACATCTGAGTTCAAATGTCTTCCCAGGCTCAGGGACCTCCATTCCTTGAGATTGTCTTGGCATGGCCCAGCCCT GCCTCATGGGATGGACAATGCATGGGGTGGTCTTTATTTTTCCCTTTCAAATAAAACACTAGTCAGGTACCGTTTTATCCCAGTCGTACT CTTCCAGGTTTGGAAGACCCAGAGAGGCCAAGATCCCATCCTTAGCCATAGCGAGCGGTGGTGGTGGATAGCATCACAAGAAACGAGCCT GAAAATCAGGTCCAGCCGGTCCAAGCACATGGCCTCCCATCTGGGAGAGCCCACTGTCCCACTCCCACATGTCTGGGCACCTGCCCTGGG CTGAGGCCAGGCTGCTCCAGGGGCCTCCTGCGCCCTCACCTGCCACAGAGCAACCCAGGTTAAATACAGCCCATGCACAAAGCCACAGGC CAAAGCCTATGGAATTGTTTTTAATCATCAAATTTAACCATTTTCATAACTGGTTCCTGGAGGTGTGCAGTGCCCCCTTGCCTCTTCAAA CCTACAGCTTCTCTTTGCCATTTGTGGATTTCACATCACTCCACACAGAAACATTACAGCCTGGCATCCCCAGTCTTTGCCTTCTTCCAG CTGCCTCGACACAGCACTGTGGCCTGTCCCTATTGCCCAGGCACGCCATTTCCAAGGGCAGGAAGGGGCAGTGTCCTGAAGCCCATCTTT TCTGTGACTGTCTTAGGTGATGTGTAGCCCCCTCCACCTTTCCACTCAACAACCTCCCACCCCTGTCCTGCTGCATGGTCCGGAGTCTGG >In-frame_ACER3_ENST00000538157_chr11_76670075_+_PPME1_ENST00000398427_chr11_73933357_+_2446nt AGCGGAGCGCCTGGGCGGCGGCGGCGGCGGCGTGATGGCTCCGGCCGCGGACCGAGAGGGCTACTGGGGCCCCACGACCTCCACGCTGGA CTGGTGCGAGGAGAACTACTCCGTGACCTGGTACATCGCCGAGTTCTGTTCCTTCCTACCATCCTCCCTGAAGAGCAACCTCAAGGAATA CAGTGAGTAACCTGATCATGATTATACCTCCAATGTTCGGTGCAGTTCAGAGTGTTAGAGACGGTCTGGAAAAGCGGTACATTGCTTCTT ATTTAGCACTCACAGTGGTAGGAATGGGATCCTGGTGCTTCCACATGACTCTGAAATATGAAATGCAGGCAGCGATTATTAGTAGAGTTC AGTGTAGGATTGTAGCTTTGGATCTGCGAAGTCATGGTGAAACAAAGGTCAAGAATCCTGAAGATCTGTCTGCAGAAACAATGGCAAAAG ACGTTGGCAATGTGGTTGAAGCCATGTATGGGGACCTTCCTCCTCCAATTATGCTGATTGGACATAGCATGGGTGGTGCTATTGCAGTCC ACACAGCATCATCCAACCTGGTACCAAGCCTCTTGGGTCTGTGCATGATTGATGTTGTAGAAGGTACAGCTATGGATGCACTTAATAGCA TGCAGAATTTCTTACGGGGTCGTCCTAAAACCTTCAAGTCTCTGGAGAATGCTATTGAATGGAGTGTGAAGAGTGGCCAGATTCGAAATC TGGAGTCTGCCCGTGTCTCAATGGTTGGCCAAGTCAAACAGTGTGAAGGAATTACAAGTCCAGAAGGCTCAAAATCTATAGTGGAAGGAA TCATAGAGGAAGAAGAAGAAGATGAGGAAGGAAGTGAGTCTATAAGCAAGAGGAAAAAGGAAGATGACATGGAGGGGTTGCCCTCGGAGA CTCAGAACTTGCTCTTATTCCTCCAGACCAAGAAAGACCATCCATACACCTGGAGAATTGAACTGGCAAAAACAGAAAAATACTGGGACG GCTGGTTCCGAGGCTTATCCAATCTCTTTCTTAGTTGTCCCATTCCTAAATTGCTGCTCTTGGCTGGTGTTGATAGATTGGATAAAGATC TGACCATTGGCCAGATGCAAGGGAAGTTCCAGATGCAGGTCCTACCCCAGTGTGGCCATGCAGTCCATGAGGATGCCCCTGACAAGGTAG CTGAAGCTGTTGCCACTTTCCTGATCCGGCACAGGTTTGCAGAACCCATCGGTGGATTCCAGTGTGTGTTTCCTGGCTGTTAGTGACCTG CTGTCCACCCCTCCTCAACATCGAGCTCTGTTGTAAATACGTCGCACCAGAGGCCACTGTGATGCCACTGTCTCCTCTCCATCCCGCCCA GCCATGTGACACTGGCTCCCGGTAGACGGGCACCCCGAGATGTACCAACCTTTTCATGTATTCTGCCAAAAGCATTGTTTTCCAGGGCCC TTGACCAACATCGGCTTCCCCAGTCCAGGGCTCCCCTGCTCCTTTCCCTTCCCTGTACTGGGGTAGCTCCTGCCTGCTCTCCCTGCGTTG CCTAGGGTAAAGCCTCCAGATTTGCCATACTGAGCCCCTCTTCCTAGCATCAGGCGATACATCTGAGTTCAAATGTCTTCCCAGGCTCAG GGACCTCCATTCCTTGAGATTGTCTTGGCATGGCCCAGCCCTGCCTCATGGGATGGACAATGCATGGGGTGGTCTTTATTTTTCCCTTTC AAATAAAACACTAGTCAGGTACCGTTTTATCCCAGTCGTACTCTTCCAGGTTTGGAAGACCCAGAGAGGCCAAGATCCCATCCTTAGCCA TAGCGAGCGGTGGTGGTGGATAGCATCACAAGAAACGAGCCTGAAAATCAGGTCCAGCCGGTCCAAGCACATGGCCTCCCATCTGGGAGA GCCCACTGTCCCACTCCCACATGTCTGGGCACCTGCCCTGGGCTGAGGCCAGGCTGCTCCAGGGGCCTCCTGCGCCCTCACCTGCCACAG AGCAACCCAGGTTAAATACAGCCCATGCACAAAGCCACAGGCCAAAGCCTATGGAATTGTTTTTAATCATCAAATTTAACCATTTTCATA ACTGGTTCCTGGAGGTGTGCAGTGCCCCCTTGCCTCTTCAAACCTACAGCTTCTCTTTGCCATTTGTGGATTTCACATCACTCCACACAG AAACATTACAGCCTGGCATCCCCAGTCTTTGCCTTCTTCCAGCTGCCTCGACACAGCACTGTGGCCTGTCCCTATTGCCCAGGCACGCCA TTTCCAAGGGCAGGAAGGGGCAGTGTCCTGAAGCCCATCTTTTCTGTGACTGTCTTAGGTGATGTGTAGCCCCCTCCACCTTTCCACTCA ACAACCTCCCACCCCTGTCCTGCTGCATGGTCCGGAGTCTGGGACCTACTTTGTTTTTTGTTATTTATGACCTTGTTTAAAGAAAATAAA |
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FusionGenePPI for ACER3_PPME1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ACER3 | ELAVL1, MLH1 | PPME1 | PPP2CA, PPP2R1A, PPP2CB, PPP2R2D, TDRD1, PPP4C, NFKB1, TJAP1, SLC9A3R1, NUDC, RPA1, GMPS, GPN1, HNRNPF, HSPBP1, OGT, PNP, ACTR2, AGFG1, ALAD, C14orf142, COASY, DBNL, ERO1L, FKBP10, P3H1, LPP, LRSAM1, PPP1R7, SURF2, TTLL12, PSMD5, RPRD1B, TOM1L1, TSTA3, WDR4, ZPR1, ACY1, PPP4R2, PPP2R5D, CAMK1, HK2, CAST, PDCD10, UNC45A, XPO5, NTRK1, CMYA5, CDH23, SYNE1, CARD14, PPME1, LRRC8E, HRNR, DHRS2, GSTO1, RAN, MYH1, CTSD, PCNA, LDHA, LDHB, MDH2, EEF1D, FDPS, GAPDH, CALR, GPI, PDIA3, P4HB, PKM, WDR1, LGALS3BP, HSPA8, LMNA, KARS, LCP1, TKT, ANXA6, EZR, PDIA4, MCM3, EEF2, HSP90B1, CSE1L, TRIM28, CLTC, FLNA, IQGAP1, RUVBL1, PPP2R2A, TMEM165, CDH1, TGM3, ENSA, GTF2E2, SMEK1, TRIM25, G3BP1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ACER3_PPME1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ACER3_PPME1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | ACER3 | C0025202 | melanoma | 1 | CTD_human |
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