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Fusion gene ID: 37988 |
FusionGeneSummary for THOC1_THADA |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: THOC1_THADA | Fusion gene ID: 37988 | Hgene | Tgene | Gene symbol | THOC1 | THADA | Gene ID | 9984 | 63892 |
| Gene name | THO complex 1 | THADA, armadillo repeat containing | |
| Synonyms | HPR1|P84|P84N5 | ARMC13|GITA | |
| Cytomap | 18p11.32 | 2p21 | |
| Type of gene | protein-coding | protein-coding | |
| Description | THO complex subunit 1hTREX84nuclear matrix protein p84tho1 | thyroid adenoma-associated proteindeath receptor-interacting proteingene inducing thyroid adenomas protein | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q96FV9 | Q6YHU6 | |
| Ensembl transtripts involved in fusion gene | ENST00000261600, ENST00000582313, | ENST00000330266, ENST00000405975, ENST00000415080, ENST00000405006, ENST00000485353, ENST00000402360, ENST00000404790, ENST00000403856, | |
| Fusion gene scores | * DoF score | 4 X 5 X 3=60 | 9 X 9 X 7=567 |
| # samples | 7 | 10 | |
| ** MAII score | log2(7/60*10)=0.222392421336448 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(10/567*10)=-2.5033487351675 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: THOC1 [Title/Abstract] AND THADA [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | THOC1 | GO:0006406 | mRNA export from nucleus | 17190602 |
| Hgene | THOC1 | GO:0006915 | apoptotic process | 10512864 |
| Hgene | THOC1 | GO:0032784 | regulation of DNA-templated transcription, elongation | 15870275 |
| Hgene | THOC1 | GO:0046784 | viral mRNA export from host cell nucleus | 18974867 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | UCS | TCGA-N8-A4PO-01A | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000261600 | ENST00000330266 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| In-frame | ENST00000261600 | ENST00000405975 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| In-frame | ENST00000261600 | ENST00000415080 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| In-frame | ENST00000261600 | ENST00000405006 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| 5CDS-5UTR | ENST00000261600 | ENST00000485353 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| 5CDS-intron | ENST00000261600 | ENST00000402360 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| 5CDS-intron | ENST00000261600 | ENST00000404790 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| 5CDS-intron | ENST00000261600 | ENST00000403856 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| 5UTR-3CDS | ENST00000582313 | ENST00000330266 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| 5UTR-3CDS | ENST00000582313 | ENST00000405975 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| 5UTR-3CDS | ENST00000582313 | ENST00000415080 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| 5UTR-3CDS | ENST00000582313 | ENST00000405006 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| 5UTR-5UTR | ENST00000582313 | ENST00000485353 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| 5UTR-intron | ENST00000582313 | ENST00000402360 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| 5UTR-intron | ENST00000582313 | ENST00000404790 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
| 5UTR-intron | ENST00000582313 | ENST00000403856 | THOC1 | chr18 | 252539 | - | THADA | chr2 | 43655370 | - |
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FusionProtFeatures for THOC1_THADA |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| THOC1 | THADA |
| Required for efficient export of polyadenylated RNA.Acts as component of the THO subcomplex of the TREX complex whichis thought to couple mRNA transcription, processing and nuclearexport, and which specifically associates with spliced mRNA andnot with unspliced pre-mRNA. TREX is recruited to spliced mRNAs bya transcription-independent mechanism, binds to mRNA upstream ofthe exon-junction complex (EJC) and is recruited in asplicing- and cap-dependent manner to a region near the 5' end ofthe mRNA where it functions in mRNA export to the cytoplasm viathe TAP/NFX1 pathway. The TREX complex is essential for the exportof Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAsand infectious virus production. Regulates transcriptionalelongation of a subset of genes. Involved in genome stability bypreventing co-transcriptional R-loop formation. Participates in an apoptotic pathway which ischaracterized by activation of caspase-6, increases in theexpression of BAK1 and BCL2L1 and activation of NF-kappa-B. Thispathway does not require p53/TP53, nor does the presence ofp53/TP53 affect the efficiency of cell killing. Activates a G2/Mcell cycle checkpoint prior to the onset of apoptosis. Apoptosisis inhibited by association with RB1. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >THADA | chr18:252539 | chr2:43655370 | ENST00000402360 | - | 0 | 17 | 886_918 | -10 | 938 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >THADA | chr18:252539 | chr2:43655370 | ENST00000402360 | - | 0 | 17 | 1322_1327 | -10 | 938 | Compositional bias | Note=Poly-Leu |
| Tgene | >THADA | chr18:252539 | chr2:43655370 | ENST00000402360 | - | 0 | 17 | 1529_1532 | -10 | 938 | Compositional bias | Note=Poly-Ala |
| Tgene | >THADA | chr18:252539 | chr2:43655370 | ENST00000402360 | - | 0 | 17 | 4_7 | -10 | 938 | Compositional bias | Note=Poly-Lys |
| Tgene | >THADA | chr18:252539 | chr2:43655370 | ENST00000405006 | - | 26 | 38 | 1322_1327 | 1308 | 1954 | Compositional bias | Note=Poly-Leu |
| Tgene | >THADA | chr18:252539 | chr2:43655370 | ENST00000405006 | - | 26 | 38 | 1529_1532 | 1308 | 1954 | Compositional bias | Note=Poly-Ala |
| Tgene | >THADA | chr18:252539 | chr2:43655370 | ENST00000405975 | - | 26 | 38 | 1322_1327 | 1308 | 1954 | Compositional bias | Note=Poly-Leu |
| Tgene | >THADA | chr18:252539 | chr2:43655370 | ENST00000405975 | - | 26 | 38 | 1529_1532 | 1308 | 1954 | Compositional bias | Note=Poly-Ala |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >THOC1 | chr18:252539 | chr2:43655370 | ENST00000261600 | - | 9 | 21 | 570_653 | 225 | 658 | Domain | Death |
| Hgene | >THOC1 | chr18:252539 | chr2:43655370 | ENST00000261600 | - | 9 | 21 | 414_430 | 225 | 658 | Motif | Nuclear localization signal |
| Tgene | THADA | chr18:252539 | chr2:43655370 | ENST00000405006 | - | 26 | 38 | 886_918 | 1308 | 1954 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | THADA | chr18:252539 | chr2:43655370 | ENST00000405975 | - | 26 | 38 | 886_918 | 1308 | 1954 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | THADA | chr18:252539 | chr2:43655370 | ENST00000405006 | - | 26 | 38 | 4_7 | 1308 | 1954 | Compositional bias | Note=Poly-Lys |
| Tgene | THADA | chr18:252539 | chr2:43655370 | ENST00000405975 | - | 26 | 38 | 4_7 | 1308 | 1954 | Compositional bias | Note=Poly-Lys |
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FusionGeneSequence for THOC1_THADA |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_THOC1_ENST00000261600_chr18_252539_-_THADA_ENST00000330266_chr2_43655370_-_305aa MSPTPPLFSLPEARTRFTKSTREALNNKNIKPLLSTFSQVPGSENEKKCTLDQAFRGILEEEIINHSSCENVLAIISLAIGGVTEGICTA STPFVLLGDVLDCLPLDQCDTIFTFVEKNVATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQ FNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDEEAPTTCDMGEPNRHPSMFLLLLVLERLYASPMDGTSSALSMGPFVPFIMR >In-frame_THOC1_ENST00000261600_chr18_252539_-_THADA_ENST00000405975_chr2_43655370_-_871aa MSPTPPLFSLPEARTRFTKSTREALNNKNIKPLLSTFSQVPGSENEKKCTLDQAFRGILEEEIINHSSCENVLAIISLAIGGVTEGICTA STPFVLLGDVLDCLPLDQCDTIFTFVEKNVATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQ FNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDEEAPTTCDMGEPNRHPSMFLLLLVLERLYASPMDGTSSALSMGPFVPFIMR CGHSPVYHSREMAARALVPFVMIDHIPNTIRTLLSTLPSCTDQCFRQNHIHGTLLQVFHLLQAYSDSKHGTNSDFQHELTDITVCTKAKL WLAKRQNPCLVTRAVYIDILFLLTCCLNRSAKDNQPVLESLGFWEEVRGIISGSELITGFPWAFKVPGLPQYLQSLTRLAIAAVWAAAAK SGERETNVPISFSQLLESAFPEVRSLTLEALLEKFLAAASGLGEKGVPPLLCNMGEKFLLLAMKENHPECFCKILKILHCMDPGEWLPQT EHCVHLTPKEFLIWTMDIASNERSEIQSVALRLASKVISHHMQTCVENRELIAAELKQWVQLVILSCEDHLPTESRLAVVEVLTSTTPLF LTNPHPILELQDTLALWKCVLTLLQSEEQAVRDAATETVTTAMSQENTCQSTEFAFCQVDASIALALALAVLCDLLQQWDQLAPGLPILL GWLLGESDDLVACVESMHQVEEDYLFEKAEVNFWAETLIFVKYLCKHLFCLLSKSGWRPPSPEMLCHLQRMVSEQCHLLSQFFRELPPAA >In-frame_THOC1_ENST00000261600_chr18_252539_-_THADA_ENST00000415080_chr2_43655370_-_871aa MSPTPPLFSLPEARTRFTKSTREALNNKNIKPLLSTFSQVPGSENEKKCTLDQAFRGILEEEIINHSSCENVLAIISLAIGGVTEGICTA STPFVLLGDVLDCLPLDQCDTIFTFVEKNVATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQ FNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDEEAPTTCDMGEPNRHPSMFLLLLVLERLYASPMDGTSSALSMGPFVPFIMR CGHSPVYHSREMAARALVPFVMIDHIPNTIRTLLSTLPSCTDQCFRQNHIHGTLLQVFHLLQAYSDSKHGTNSDFQHELTDITVCTKAKL WLAKRQNPCLVTRAVYIDILFLLTCCLNRSAKDNQPVLESLGFWEEVRGIISGSELITGFPWAFKVPGLPQYLQSLTRLAIAAVWAAAAK SGERETNVPISFSQLLESAFPEVRSLTLEALLEKFLAAASGLGEKGVPPLLCNMGEKFLLLAMKENHPECFCKILKILHCMDPGEWLPQT EHCVHLTPKEFLIWTMDIASNERSEIQSVALRLASKVISHHMQTCVENRELIAAELKQWVQLVILSCEDHLPTESRLAVVEVLTSTTPLF LTNPHPILELQDTLALWKCVLTLLQSEEQAVRDAATETVTTAMSQENTCQSTEFAFCQVDASIALALALAVLCDLLQQWDQLAPGLPILL GWLLGESDDLVACVESMHQVEEDYLFEKAEVNFWAETLIFVKYLCKHLFCLLSKSGWRPPSPEMLCHLQRMVSEQCHLLSQFFRELPPAA >In-frame_THOC1_ENST00000261600_chr18_252539_-_THADA_ENST00000405006_chr2_43655370_-_871aa MSPTPPLFSLPEARTRFTKSTREALNNKNIKPLLSTFSQVPGSENEKKCTLDQAFRGILEEEIINHSSCENVLAIISLAIGGVTEGICTA STPFVLLGDVLDCLPLDQCDTIFTFVEKNVATWKSNTFYSAGKNYLLRMCNDLLRRLSKSQNTVFCGRIQLFLARLFPLSEKSGLNLQSQ FNLENVTVFNTNEQESTLGQKHTEDREEGMDVEEGEMGDEEAPTTCDMGEPNRHPSMFLLLLVLERLYASPMDGTSSALSMGPFVPFIMR CGHSPVYHSREMAARALVPFVMIDHIPNTIRTLLSTLPSCTDQCFRQNHIHGTLLQVFHLLQAYSDSKHGTNSDFQHELTDITVCTKAKL WLAKRQNPCLVTRAVYIDILFLLTCCLNRSAKDNQPVLESLGFWEEVRGIISGSELITGFPWAFKVPGLPQYLQSLTRLAIAAVWAAAAK SGERETNVPISFSQLLESAFPEVRSLTLEALLEKFLAAASGLGEKGVPPLLCNMGEKFLLLAMKENHPECFCKILKILHCMDPGEWLPQT EHCVHLTPKEFLIWTMDIASNERSEIQSVALRLASKVISHHMQTCVENRELIAAELKQWVQLVILSCEDHLPTESRLAVVEVLTSTTPLF LTNPHPILELQDTLALWKCVLTLLQSEEQAVRDAATETVTTAMSQENTCQSTEFAFCQVDASIALALALAVLCDLLQQWDQLAPGLPILL GWLLGESDDLVACVESMHQVEEDYLFEKAEVNFWAETLIFVKYLCKHLFCLLSKSGWRPPSPEMLCHLQRMVSEQCHLLSQFFRELPPAA |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_THOC1_ENST00000261600_chr18_252539_-_THADA_ENST00000330266_chr2_43655370_-_915nt ATGTCTCCGACGCCGCCGCTCTTCAGTTTGCCCGAAGCGCGGACGCGGTTTACGAAGTCTACCAGAGAGGCCTTGAACAACAAAAACATC AAGCCATTGTTAAGTACCTTCAGCCAGGTACCTGGCAGTGAAAATGAAAAAAAATGTACCCTTGACCAAGCTTTCAGAGGTATTCTAGAA GAAGAAATTATAAATCATTCATCATGTGAAAACGTTTTAGCTATTATTTCTCTTGCTATTGGGGGAGTAACTGAAGGTATTTGTACCGCA TCTACACCTTTTGTATTGTTGGGAGATGTTTTGGATTGTCTTCCTTTGGATCAGTGTGACACAATATTCACTTTTGTGGAAAAAAATGTT GCTACTTGGAAATCAAATACATTCTATTCTGCTGGGAAAAATTACTTACTACGTATGTGCAATGATCTCCTAAGAAGATTGTCTAAATCC CAGAATACAGTCTTCTGTGGACGGATTCAGCTCTTTTTGGCCAGGCTTTTCCCTCTGTCTGAGAAATCAGGTCTTAACTTGCAGAGTCAG TTTAATCTGGAAAATGTCACTGTTTTCAATACAAATGAGCAGGAAAGCACCCTGGGTCAGAAGCACACTGAAGATAGAGAAGAAGGAATG GATGTAGAAGAAGGCGAAATGGGAGACGAGGAAGCTCCAACAACGTGTGATATGGGAGAACCAAATCGTCATCCAAGCATGTTTCTCTTA CTTTTGGTGTTGGAGAGACTCTACGCTTCCCCGATGGATGGTACTTCTTCTGCTCTCAGCATGGGACCTTTTGTTCCCTTCATTATGAGA GTCTTGCTCTGTTGTCCAGGCTGGAGTGCAGTGGCACGATCTCAGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCAATTCTCCTGCCT >In-frame_THOC1_ENST00000261600_chr18_252539_-_THADA_ENST00000405975_chr2_43655370_-_2613nt ATGTCTCCGACGCCGCCGCTCTTCAGTTTGCCCGAAGCGCGGACGCGGTTTACGAAGTCTACCAGAGAGGCCTTGAACAACAAAAACATC AAGCCATTGTTAAGTACCTTCAGCCAGGTACCTGGCAGTGAAAATGAAAAAAAATGTACCCTTGACCAAGCTTTCAGAGGTATTCTAGAA GAAGAAATTATAAATCATTCATCATGTGAAAACGTTTTAGCTATTATTTCTCTTGCTATTGGGGGAGTAACTGAAGGTATTTGTACCGCA TCTACACCTTTTGTATTGTTGGGAGATGTTTTGGATTGTCTTCCTTTGGATCAGTGTGACACAATATTCACTTTTGTGGAAAAAAATGTT GCTACTTGGAAATCAAATACATTCTATTCTGCTGGGAAAAATTACTTACTACGTATGTGCAATGATCTCCTAAGAAGATTGTCTAAATCC CAGAATACAGTCTTCTGTGGACGGATTCAGCTCTTTTTGGCCAGGCTTTTCCCTCTGTCTGAGAAATCAGGTCTTAACTTGCAGAGTCAG TTTAATCTGGAAAATGTCACTGTTTTCAATACAAATGAGCAGGAAAGCACCCTGGGTCAGAAGCACACTGAAGATAGAGAAGAAGGAATG GATGTAGAAGAAGGCGAAATGGGAGACGAGGAAGCTCCAACAACGTGTGATATGGGAGAACCAAATCGTCATCCAAGCATGTTTCTCTTA CTTTTGGTGTTGGAGAGACTCTACGCTTCCCCGATGGATGGTACTTCTTCTGCTCTCAGCATGGGACCTTTTGTTCCCTTCATTATGAGG TGTGGTCACTCACCTGTCTACCACTCCCGTGAAATGGCAGCTCGTGCCTTGGTCCCATTTGTTATGATAGATCACATTCCTAATACCATT CGAACTCTGTTGTCCACACTCCCCAGCTGCACTGACCAGTGTTTCCGGCAAAACCACATTCATGGGACACTTCTCCAGGTTTTTCATTTG TTGCAAGCCTACTCAGACTCCAAACACGGAACGAATTCAGACTTCCAGCACGAGCTGACTGACATCACTGTTTGTACCAAAGCCAAACTC TGGCTGGCCAAGAGGCAAAATCCATGTTTGGTGACCAGAGCTGTATATATTGATATTCTCTTCCTATTGACTTGCTGCCTCAACAGATCT GCAAAGGACAACCAGCCAGTTCTGGAGAGTCTTGGCTTCTGGGAGGAAGTCAGAGGGATTATCTCAGGATCAGAGCTGATAACGGGATTC CCTTGGGCCTTCAAGGTGCCAGGCCTGCCCCAGTACCTCCAGAGCCTCACCAGACTAGCCATTGCTGCAGTGTGGGCCGCGGCAGCCAAG AGTGGAGAGCGGGAGACGAATGTCCCCATCTCTTTCTCTCAGCTGTTAGAATCTGCCTTCCCTGAAGTGCGCTCACTAACACTGGAAGCC CTCTTGGAAAAGTTCTTAGCAGCAGCCTCTGGACTTGGAGAGAAGGGCGTGCCACCCTTGCTGTGCAACATGGGAGAGAAGTTCTTATTG TTGGCCATGAAGGAAAATCACCCAGAATGCTTCTGCAAGATACTGAAAATTCTCCACTGCATGGACCCTGGTGAGTGGCTTCCCCAGACG GAGCACTGTGTCCATCTGACCCCAAAGGAGTTCTTGATCTGGACGATGGATATTGCTTCCAATGAAAGATCTGAAATTCAGAGTGTAGCT CTGAGACTTGCTTCCAAAGTCATTTCCCACCACATGCAGACATGTGTGGAGAACAGGGAATTGATAGCTGCTGAGCTGAAGCAGTGGGTT CAGCTGGTCATCTTGTCATGTGAAGACCATCTTCCTACAGAGTCTAGGCTGGCCGTCGTTGAAGTCCTCACCAGTACTACACCACTTTTC CTCACCAACCCCCATCCTATTCTTGAGTTGCAGGATACACTTGCTCTCTGGAAGTGTGTCCTTACCCTTCTGCAGAGTGAGGAGCAAGCT GTTAGAGATGCAGCCACGGAAACCGTGACAACTGCCATGTCACAAGAAAATACCTGCCAGTCAACAGAGTTTGCCTTCTGCCAGGTGGAT GCCTCCATCGCTCTGGCCCTGGCCCTGGCCGTCCTGTGTGATCTGCTCCAGCAGTGGGACCAGTTGGCCCCTGGACTGCCCATCCTGCTG GGATGGCTGTTGGGAGAGAGTGATGACCTCGTGGCCTGTGTGGAGAGCATGCATCAGGTGGAAGAAGACTACCTGTTTGAAAAAGCAGAA GTCAACTTTTGGGCCGAGACCCTGATCTTTGTGAAATACCTCTGCAAGCACCTCTTCTGTCTCCTCTCAAAGTCCGGCTGGCGTCCCCCA AGCCCTGAGATGCTCTGTCACCTTCAAAGGATGGTGTCAGAGCAGTGCCACCTCCTGTCTCAGTTCTTCAGAGAGCTTCCACCAGCTGCT GAGTTTGTGAAGACAGTGGAGTTCACAAGACTACGCATTCAAGAGGAAAGGACTTTGGCTTGCTTGAGGCTGCTGGCCTTTTTGGAAGGA AAGGAAGGGGAAGACACCCTAGTTCTCAGTGTTTGGGACTCTTATGCAGAATCGAGGCAGTTAACTCTTCCAAGAACAGAAGCGGCATGT >In-frame_THOC1_ENST00000261600_chr18_252539_-_THADA_ENST00000415080_chr2_43655370_-_2613nt ATGTCTCCGACGCCGCCGCTCTTCAGTTTGCCCGAAGCGCGGACGCGGTTTACGAAGTCTACCAGAGAGGCCTTGAACAACAAAAACATC AAGCCATTGTTAAGTACCTTCAGCCAGGTACCTGGCAGTGAAAATGAAAAAAAATGTACCCTTGACCAAGCTTTCAGAGGTATTCTAGAA GAAGAAATTATAAATCATTCATCATGTGAAAACGTTTTAGCTATTATTTCTCTTGCTATTGGGGGAGTAACTGAAGGTATTTGTACCGCA TCTACACCTTTTGTATTGTTGGGAGATGTTTTGGATTGTCTTCCTTTGGATCAGTGTGACACAATATTCACTTTTGTGGAAAAAAATGTT GCTACTTGGAAATCAAATACATTCTATTCTGCTGGGAAAAATTACTTACTACGTATGTGCAATGATCTCCTAAGAAGATTGTCTAAATCC CAGAATACAGTCTTCTGTGGACGGATTCAGCTCTTTTTGGCCAGGCTTTTCCCTCTGTCTGAGAAATCAGGTCTTAACTTGCAGAGTCAG TTTAATCTGGAAAATGTCACTGTTTTCAATACAAATGAGCAGGAAAGCACCCTGGGTCAGAAGCACACTGAAGATAGAGAAGAAGGAATG GATGTAGAAGAAGGCGAAATGGGAGACGAGGAAGCTCCAACAACGTGTGATATGGGAGAACCAAATCGTCATCCAAGCATGTTTCTCTTA CTTTTGGTGTTGGAGAGACTCTACGCTTCCCCGATGGATGGTACTTCTTCTGCTCTCAGCATGGGACCTTTTGTTCCCTTCATTATGAGG TGTGGTCACTCACCTGTCTACCACTCCCGTGAAATGGCAGCTCGTGCCTTGGTCCCATTTGTTATGATAGATCACATTCCTAATACCATT CGAACTCTGTTGTCCACACTCCCCAGCTGCACTGACCAGTGTTTCCGGCAAAACCACATTCATGGGACACTTCTCCAGGTTTTTCATTTG TTGCAAGCCTACTCAGACTCCAAACACGGAACGAATTCAGACTTCCAGCACGAGCTGACTGACATCACTGTTTGTACCAAAGCCAAACTC TGGCTGGCCAAGAGGCAAAATCCATGTTTGGTGACCAGAGCTGTATATATTGATATTCTCTTCCTATTGACTTGCTGCCTCAACAGATCT GCAAAGGACAACCAGCCAGTTCTGGAGAGTCTTGGCTTCTGGGAGGAAGTCAGAGGGATTATCTCAGGATCAGAGCTGATAACGGGATTC CCTTGGGCCTTCAAGGTGCCAGGCCTGCCCCAGTACCTCCAGAGCCTCACCAGACTAGCCATTGCTGCAGTGTGGGCCGCGGCAGCCAAG AGTGGAGAGCGGGAGACGAATGTCCCCATCTCTTTCTCTCAGCTGTTAGAATCTGCCTTCCCTGAAGTGCGCTCACTAACACTGGAAGCC CTCTTGGAAAAGTTCTTAGCAGCAGCCTCTGGACTTGGAGAGAAGGGCGTGCCACCCTTGCTGTGCAACATGGGAGAGAAGTTCTTATTG TTGGCCATGAAGGAAAATCACCCAGAATGCTTCTGCAAGATACTGAAAATTCTCCACTGCATGGACCCTGGTGAGTGGCTTCCCCAGACG GAGCACTGTGTCCATCTGACCCCAAAGGAGTTCTTGATCTGGACGATGGATATTGCTTCCAATGAAAGATCTGAAATTCAGAGTGTAGCT CTGAGACTTGCTTCCAAAGTCATTTCCCACCACATGCAGACATGTGTGGAGAACAGGGAATTGATAGCTGCTGAGCTGAAGCAGTGGGTT CAGCTGGTCATCTTGTCATGTGAAGACCATCTTCCTACAGAGTCTAGGCTGGCCGTCGTTGAAGTCCTCACCAGTACTACACCACTTTTC CTCACCAACCCCCATCCTATTCTTGAGTTGCAGGATACACTTGCTCTCTGGAAGTGTGTCCTTACCCTTCTGCAGAGTGAGGAGCAAGCT GTTAGAGATGCAGCCACGGAAACCGTGACAACTGCCATGTCACAAGAAAATACCTGCCAGTCAACAGAGTTTGCCTTCTGCCAGGTGGAT GCCTCCATCGCTCTGGCCCTGGCCCTGGCCGTCCTGTGTGATCTGCTCCAGCAGTGGGACCAGTTGGCCCCTGGACTGCCCATCCTGCTG GGATGGCTGTTGGGAGAGAGTGATGACCTCGTGGCCTGTGTGGAGAGCATGCATCAGGTGGAAGAAGACTACCTGTTTGAAAAAGCAGAA GTCAACTTTTGGGCCGAGACCCTGATCTTTGTGAAATACCTCTGCAAGCACCTCTTCTGTCTCCTCTCAAAGTCCGGCTGGCGTCCCCCA AGCCCTGAGATGCTCTGTCACCTTCAAAGGATGGTGTCAGAGCAGTGCCACCTCCTGTCTCAGTTCTTCAGAGAGCTTCCACCAGCTGCT GAGTTTGTGAAGACAGTGGAGTTCACAAGACTACGCATTCAAGAGGAAAGGACTTTGGCTTGCTTGAGGCTGCTGGCCTTTTTGGAAGGA AAGGAAGGGGAAGACACCCTAGTTCTCAGTGTTTGGGACTCTTATGCAGAATCGAGGCAGTTAACTCTTCCAAGAACAGAAGCGGCATGT >In-frame_THOC1_ENST00000261600_chr18_252539_-_THADA_ENST00000405006_chr2_43655370_-_2613nt ATGTCTCCGACGCCGCCGCTCTTCAGTTTGCCCGAAGCGCGGACGCGGTTTACGAAGTCTACCAGAGAGGCCTTGAACAACAAAAACATC AAGCCATTGTTAAGTACCTTCAGCCAGGTACCTGGCAGTGAAAATGAAAAAAAATGTACCCTTGACCAAGCTTTCAGAGGTATTCTAGAA GAAGAAATTATAAATCATTCATCATGTGAAAACGTTTTAGCTATTATTTCTCTTGCTATTGGGGGAGTAACTGAAGGTATTTGTACCGCA TCTACACCTTTTGTATTGTTGGGAGATGTTTTGGATTGTCTTCCTTTGGATCAGTGTGACACAATATTCACTTTTGTGGAAAAAAATGTT GCTACTTGGAAATCAAATACATTCTATTCTGCTGGGAAAAATTACTTACTACGTATGTGCAATGATCTCCTAAGAAGATTGTCTAAATCC CAGAATACAGTCTTCTGTGGACGGATTCAGCTCTTTTTGGCCAGGCTTTTCCCTCTGTCTGAGAAATCAGGTCTTAACTTGCAGAGTCAG TTTAATCTGGAAAATGTCACTGTTTTCAATACAAATGAGCAGGAAAGCACCCTGGGTCAGAAGCACACTGAAGATAGAGAAGAAGGAATG GATGTAGAAGAAGGCGAAATGGGAGACGAGGAAGCTCCAACAACGTGTGATATGGGAGAACCAAATCGTCATCCAAGCATGTTTCTCTTA CTTTTGGTGTTGGAGAGACTCTACGCTTCCCCGATGGATGGTACTTCTTCTGCTCTCAGCATGGGACCTTTTGTTCCCTTCATTATGAGG TGTGGTCACTCACCTGTCTACCACTCCCGTGAAATGGCAGCTCGTGCCTTGGTCCCATTTGTTATGATAGATCACATTCCTAATACCATT CGAACTCTGTTGTCCACACTCCCCAGCTGCACTGACCAGTGTTTCCGGCAAAACCACATTCATGGGACACTTCTCCAGGTTTTTCATTTG TTGCAAGCCTACTCAGACTCCAAACACGGAACGAATTCAGACTTCCAGCACGAGCTGACTGACATCACTGTTTGTACCAAAGCCAAACTC TGGCTGGCCAAGAGGCAAAATCCATGTTTGGTGACCAGAGCTGTATATATTGATATTCTCTTCCTATTGACTTGCTGCCTCAACAGATCT GCAAAGGACAACCAGCCAGTTCTGGAGAGTCTTGGCTTCTGGGAGGAAGTCAGAGGGATTATCTCAGGATCAGAGCTGATAACGGGATTC CCTTGGGCCTTCAAGGTGCCAGGCCTGCCCCAGTACCTCCAGAGCCTCACCAGACTAGCCATTGCTGCAGTGTGGGCCGCGGCAGCCAAG AGTGGAGAGCGGGAGACGAATGTCCCCATCTCTTTCTCTCAGCTGTTAGAATCTGCCTTCCCTGAAGTGCGCTCACTAACACTGGAAGCC CTCTTGGAAAAGTTCTTAGCAGCAGCCTCTGGACTTGGAGAGAAGGGCGTGCCACCCTTGCTGTGCAACATGGGAGAGAAGTTCTTATTG TTGGCCATGAAGGAAAATCACCCAGAATGCTTCTGCAAGATACTGAAAATTCTCCACTGCATGGACCCTGGTGAGTGGCTTCCCCAGACG GAGCACTGTGTCCATCTGACCCCAAAGGAGTTCTTGATCTGGACGATGGATATTGCTTCCAATGAAAGATCTGAAATTCAGAGTGTAGCT CTGAGACTTGCTTCCAAAGTCATTTCCCACCACATGCAGACATGTGTGGAGAACAGGGAATTGATAGCTGCTGAGCTGAAGCAGTGGGTT CAGCTGGTCATCTTGTCATGTGAAGACCATCTTCCTACAGAGTCTAGGCTGGCCGTCGTTGAAGTCCTCACCAGTACTACACCACTTTTC CTCACCAACCCCCATCCTATTCTTGAGTTGCAGGATACACTTGCTCTCTGGAAGTGTGTCCTTACCCTTCTGCAGAGTGAGGAGCAAGCT GTTAGAGATGCAGCCACGGAAACCGTGACAACTGCCATGTCACAAGAAAATACCTGCCAGTCAACAGAGTTTGCCTTCTGCCAGGTGGAT GCCTCCATCGCTCTGGCCCTGGCCCTGGCCGTCCTGTGTGATCTGCTCCAGCAGTGGGACCAGTTGGCCCCTGGACTGCCCATCCTGCTG GGATGGCTGTTGGGAGAGAGTGATGACCTCGTGGCCTGTGTGGAGAGCATGCATCAGGTGGAAGAAGACTACCTGTTTGAAAAAGCAGAA GTCAACTTTTGGGCCGAGACCCTGATCTTTGTGAAATACCTCTGCAAGCACCTCTTCTGTCTCCTCTCAAAGTCCGGCTGGCGTCCCCCA AGCCCTGAGATGCTCTGTCACCTTCAAAGGATGGTGTCAGAGCAGTGCCACCTCCTGTCTCAGTTCTTCAGAGAGCTTCCACCAGCTGCT GAGTTTGTGAAGACAGTGGAGTTCACAAGACTACGCATTCAAGAGGAAAGGACTTTGGCTTGCTTGAGGCTGCTGGCCTTTTTGGAAGGA AAGGAAGGGGAAGACACCCTAGTTCTCAGTGTTTGGGACTCTTATGCAGAATCGAGGCAGTTAACTCTTCCAAGAACAGAAGCGGCATGT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_THOC1_ENST00000261600_chr18_252539_-_THADA_ENST00000330266_chr2_43655370_-_923nt CCGAGAAGATGTCTCCGACGCCGCCGCTCTTCAGTTTGCCCGAAGCGCGGACGCGGTTTACGAAGTCTACCAGAGAGGCCTTGAACAACA AAAACATCAAGCCATTGTTAAGTACCTTCAGCCAGGTACCTGGCAGTGAAAATGAAAAAAAATGTACCCTTGACCAAGCTTTCAGAGGTA TTCTAGAAGAAGAAATTATAAATCATTCATCATGTGAAAACGTTTTAGCTATTATTTCTCTTGCTATTGGGGGAGTAACTGAAGGTATTT GTACCGCATCTACACCTTTTGTATTGTTGGGAGATGTTTTGGATTGTCTTCCTTTGGATCAGTGTGACACAATATTCACTTTTGTGGAAA AAAATGTTGCTACTTGGAAATCAAATACATTCTATTCTGCTGGGAAAAATTACTTACTACGTATGTGCAATGATCTCCTAAGAAGATTGT CTAAATCCCAGAATACAGTCTTCTGTGGACGGATTCAGCTCTTTTTGGCCAGGCTTTTCCCTCTGTCTGAGAAATCAGGTCTTAACTTGC AGAGTCAGTTTAATCTGGAAAATGTCACTGTTTTCAATACAAATGAGCAGGAAAGCACCCTGGGTCAGAAGCACACTGAAGATAGAGAAG AAGGAATGGATGTAGAAGAAGGCGAAATGGGAGACGAGGAAGCTCCAACAACGTGTGATATGGGAGAACCAAATCGTCATCCAAGCATGT TTCTCTTACTTTTGGTGTTGGAGAGACTCTACGCTTCCCCGATGGATGGTACTTCTTCTGCTCTCAGCATGGGACCTTTTGTTCCCTTCA TTATGAGAGTCTTGCTCTGTTGTCCAGGCTGGAGTGCAGTGGCACGATCTCAGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCAATTC >In-frame_THOC1_ENST00000261600_chr18_252539_-_THADA_ENST00000405975_chr2_43655370_-_2733nt CCGAGAAGATGTCTCCGACGCCGCCGCTCTTCAGTTTGCCCGAAGCGCGGACGCGGTTTACGAAGTCTACCAGAGAGGCCTTGAACAACA AAAACATCAAGCCATTGTTAAGTACCTTCAGCCAGGTACCTGGCAGTGAAAATGAAAAAAAATGTACCCTTGACCAAGCTTTCAGAGGTA TTCTAGAAGAAGAAATTATAAATCATTCATCATGTGAAAACGTTTTAGCTATTATTTCTCTTGCTATTGGGGGAGTAACTGAAGGTATTT GTACCGCATCTACACCTTTTGTATTGTTGGGAGATGTTTTGGATTGTCTTCCTTTGGATCAGTGTGACACAATATTCACTTTTGTGGAAA AAAATGTTGCTACTTGGAAATCAAATACATTCTATTCTGCTGGGAAAAATTACTTACTACGTATGTGCAATGATCTCCTAAGAAGATTGT CTAAATCCCAGAATACAGTCTTCTGTGGACGGATTCAGCTCTTTTTGGCCAGGCTTTTCCCTCTGTCTGAGAAATCAGGTCTTAACTTGC AGAGTCAGTTTAATCTGGAAAATGTCACTGTTTTCAATACAAATGAGCAGGAAAGCACCCTGGGTCAGAAGCACACTGAAGATAGAGAAG AAGGAATGGATGTAGAAGAAGGCGAAATGGGAGACGAGGAAGCTCCAACAACGTGTGATATGGGAGAACCAAATCGTCATCCAAGCATGT TTCTCTTACTTTTGGTGTTGGAGAGACTCTACGCTTCCCCGATGGATGGTACTTCTTCTGCTCTCAGCATGGGACCTTTTGTTCCCTTCA TTATGAGGTGTGGTCACTCACCTGTCTACCACTCCCGTGAAATGGCAGCTCGTGCCTTGGTCCCATTTGTTATGATAGATCACATTCCTA ATACCATTCGAACTCTGTTGTCCACACTCCCCAGCTGCACTGACCAGTGTTTCCGGCAAAACCACATTCATGGGACACTTCTCCAGGTTT TTCATTTGTTGCAAGCCTACTCAGACTCCAAACACGGAACGAATTCAGACTTCCAGCACGAGCTGACTGACATCACTGTTTGTACCAAAG CCAAACTCTGGCTGGCCAAGAGGCAAAATCCATGTTTGGTGACCAGAGCTGTATATATTGATATTCTCTTCCTATTGACTTGCTGCCTCA ACAGATCTGCAAAGGACAACCAGCCAGTTCTGGAGAGTCTTGGCTTCTGGGAGGAAGTCAGAGGGATTATCTCAGGATCAGAGCTGATAA CGGGATTCCCTTGGGCCTTCAAGGTGCCAGGCCTGCCCCAGTACCTCCAGAGCCTCACCAGACTAGCCATTGCTGCAGTGTGGGCCGCGG CAGCCAAGAGTGGAGAGCGGGAGACGAATGTCCCCATCTCTTTCTCTCAGCTGTTAGAATCTGCCTTCCCTGAAGTGCGCTCACTAACAC TGGAAGCCCTCTTGGAAAAGTTCTTAGCAGCAGCCTCTGGACTTGGAGAGAAGGGCGTGCCACCCTTGCTGTGCAACATGGGAGAGAAGT TCTTATTGTTGGCCATGAAGGAAAATCACCCAGAATGCTTCTGCAAGATACTGAAAATTCTCCACTGCATGGACCCTGGTGAGTGGCTTC CCCAGACGGAGCACTGTGTCCATCTGACCCCAAAGGAGTTCTTGATCTGGACGATGGATATTGCTTCCAATGAAAGATCTGAAATTCAGA GTGTAGCTCTGAGACTTGCTTCCAAAGTCATTTCCCACCACATGCAGACATGTGTGGAGAACAGGGAATTGATAGCTGCTGAGCTGAAGC AGTGGGTTCAGCTGGTCATCTTGTCATGTGAAGACCATCTTCCTACAGAGTCTAGGCTGGCCGTCGTTGAAGTCCTCACCAGTACTACAC CACTTTTCCTCACCAACCCCCATCCTATTCTTGAGTTGCAGGATACACTTGCTCTCTGGAAGTGTGTCCTTACCCTTCTGCAGAGTGAGG AGCAAGCTGTTAGAGATGCAGCCACGGAAACCGTGACAACTGCCATGTCACAAGAAAATACCTGCCAGTCAACAGAGTTTGCCTTCTGCC AGGTGGATGCCTCCATCGCTCTGGCCCTGGCCCTGGCCGTCCTGTGTGATCTGCTCCAGCAGTGGGACCAGTTGGCCCCTGGACTGCCCA TCCTGCTGGGATGGCTGTTGGGAGAGAGTGATGACCTCGTGGCCTGTGTGGAGAGCATGCATCAGGTGGAAGAAGACTACCTGTTTGAAA AAGCAGAAGTCAACTTTTGGGCCGAGACCCTGATCTTTGTGAAATACCTCTGCAAGCACCTCTTCTGTCTCCTCTCAAAGTCCGGCTGGC GTCCCCCAAGCCCTGAGATGCTCTGTCACCTTCAAAGGATGGTGTCAGAGCAGTGCCACCTCCTGTCTCAGTTCTTCAGAGAGCTTCCAC CAGCTGCTGAGTTTGTGAAGACAGTGGAGTTCACAAGACTACGCATTCAAGAGGAAAGGACTTTGGCTTGCTTGAGGCTGCTGGCCTTTT TGGAAGGAAAGGAAGGGGAAGACACCCTAGTTCTCAGTGTTTGGGACTCTTATGCAGAATCGAGGCAGTTAACTCTTCCAAGAACAGAAG CGGCATGTTGAAGAAAATCTGGGGGATTGGGATGGGGGTATGTGTGGATTTTTCCTCCACTAAATCTGCAGGAAACATGTTGAACATAAA >In-frame_THOC1_ENST00000261600_chr18_252539_-_THADA_ENST00000415080_chr2_43655370_-_2732nt CCGAGAAGATGTCTCCGACGCCGCCGCTCTTCAGTTTGCCCGAAGCGCGGACGCGGTTTACGAAGTCTACCAGAGAGGCCTTGAACAACA AAAACATCAAGCCATTGTTAAGTACCTTCAGCCAGGTACCTGGCAGTGAAAATGAAAAAAAATGTACCCTTGACCAAGCTTTCAGAGGTA TTCTAGAAGAAGAAATTATAAATCATTCATCATGTGAAAACGTTTTAGCTATTATTTCTCTTGCTATTGGGGGAGTAACTGAAGGTATTT GTACCGCATCTACACCTTTTGTATTGTTGGGAGATGTTTTGGATTGTCTTCCTTTGGATCAGTGTGACACAATATTCACTTTTGTGGAAA AAAATGTTGCTACTTGGAAATCAAATACATTCTATTCTGCTGGGAAAAATTACTTACTACGTATGTGCAATGATCTCCTAAGAAGATTGT CTAAATCCCAGAATACAGTCTTCTGTGGACGGATTCAGCTCTTTTTGGCCAGGCTTTTCCCTCTGTCTGAGAAATCAGGTCTTAACTTGC AGAGTCAGTTTAATCTGGAAAATGTCACTGTTTTCAATACAAATGAGCAGGAAAGCACCCTGGGTCAGAAGCACACTGAAGATAGAGAAG AAGGAATGGATGTAGAAGAAGGCGAAATGGGAGACGAGGAAGCTCCAACAACGTGTGATATGGGAGAACCAAATCGTCATCCAAGCATGT TTCTCTTACTTTTGGTGTTGGAGAGACTCTACGCTTCCCCGATGGATGGTACTTCTTCTGCTCTCAGCATGGGACCTTTTGTTCCCTTCA TTATGAGGTGTGGTCACTCACCTGTCTACCACTCCCGTGAAATGGCAGCTCGTGCCTTGGTCCCATTTGTTATGATAGATCACATTCCTA ATACCATTCGAACTCTGTTGTCCACACTCCCCAGCTGCACTGACCAGTGTTTCCGGCAAAACCACATTCATGGGACACTTCTCCAGGTTT TTCATTTGTTGCAAGCCTACTCAGACTCCAAACACGGAACGAATTCAGACTTCCAGCACGAGCTGACTGACATCACTGTTTGTACCAAAG CCAAACTCTGGCTGGCCAAGAGGCAAAATCCATGTTTGGTGACCAGAGCTGTATATATTGATATTCTCTTCCTATTGACTTGCTGCCTCA ACAGATCTGCAAAGGACAACCAGCCAGTTCTGGAGAGTCTTGGCTTCTGGGAGGAAGTCAGAGGGATTATCTCAGGATCAGAGCTGATAA CGGGATTCCCTTGGGCCTTCAAGGTGCCAGGCCTGCCCCAGTACCTCCAGAGCCTCACCAGACTAGCCATTGCTGCAGTGTGGGCCGCGG CAGCCAAGAGTGGAGAGCGGGAGACGAATGTCCCCATCTCTTTCTCTCAGCTGTTAGAATCTGCCTTCCCTGAAGTGCGCTCACTAACAC TGGAAGCCCTCTTGGAAAAGTTCTTAGCAGCAGCCTCTGGACTTGGAGAGAAGGGCGTGCCACCCTTGCTGTGCAACATGGGAGAGAAGT TCTTATTGTTGGCCATGAAGGAAAATCACCCAGAATGCTTCTGCAAGATACTGAAAATTCTCCACTGCATGGACCCTGGTGAGTGGCTTC CCCAGACGGAGCACTGTGTCCATCTGACCCCAAAGGAGTTCTTGATCTGGACGATGGATATTGCTTCCAATGAAAGATCTGAAATTCAGA GTGTAGCTCTGAGACTTGCTTCCAAAGTCATTTCCCACCACATGCAGACATGTGTGGAGAACAGGGAATTGATAGCTGCTGAGCTGAAGC AGTGGGTTCAGCTGGTCATCTTGTCATGTGAAGACCATCTTCCTACAGAGTCTAGGCTGGCCGTCGTTGAAGTCCTCACCAGTACTACAC CACTTTTCCTCACCAACCCCCATCCTATTCTTGAGTTGCAGGATACACTTGCTCTCTGGAAGTGTGTCCTTACCCTTCTGCAGAGTGAGG AGCAAGCTGTTAGAGATGCAGCCACGGAAACCGTGACAACTGCCATGTCACAAGAAAATACCTGCCAGTCAACAGAGTTTGCCTTCTGCC AGGTGGATGCCTCCATCGCTCTGGCCCTGGCCCTGGCCGTCCTGTGTGATCTGCTCCAGCAGTGGGACCAGTTGGCCCCTGGACTGCCCA TCCTGCTGGGATGGCTGTTGGGAGAGAGTGATGACCTCGTGGCCTGTGTGGAGAGCATGCATCAGGTGGAAGAAGACTACCTGTTTGAAA AAGCAGAAGTCAACTTTTGGGCCGAGACCCTGATCTTTGTGAAATACCTCTGCAAGCACCTCTTCTGTCTCCTCTCAAAGTCCGGCTGGC GTCCCCCAAGCCCTGAGATGCTCTGTCACCTTCAAAGGATGGTGTCAGAGCAGTGCCACCTCCTGTCTCAGTTCTTCAGAGAGCTTCCAC CAGCTGCTGAGTTTGTGAAGACAGTGGAGTTCACAAGACTACGCATTCAAGAGGAAAGGACTTTGGCTTGCTTGAGGCTGCTGGCCTTTT TGGAAGGAAAGGAAGGGGAAGACACCCTAGTTCTCAGTGTTTGGGACTCTTATGCAGAATCGAGGCAGTTAACTCTTCCAAGAACAGAAG CGGCATGTTGAAGAAAATCTGGGGGATTGGGATGGGGGTATGTGTGGATTTTTCCTCCACTAAATCTGCAGGAAACATGTTGAACATAAA >In-frame_THOC1_ENST00000261600_chr18_252539_-_THADA_ENST00000405006_chr2_43655370_-_2717nt CCGAGAAGATGTCTCCGACGCCGCCGCTCTTCAGTTTGCCCGAAGCGCGGACGCGGTTTACGAAGTCTACCAGAGAGGCCTTGAACAACA AAAACATCAAGCCATTGTTAAGTACCTTCAGCCAGGTACCTGGCAGTGAAAATGAAAAAAAATGTACCCTTGACCAAGCTTTCAGAGGTA TTCTAGAAGAAGAAATTATAAATCATTCATCATGTGAAAACGTTTTAGCTATTATTTCTCTTGCTATTGGGGGAGTAACTGAAGGTATTT GTACCGCATCTACACCTTTTGTATTGTTGGGAGATGTTTTGGATTGTCTTCCTTTGGATCAGTGTGACACAATATTCACTTTTGTGGAAA AAAATGTTGCTACTTGGAAATCAAATACATTCTATTCTGCTGGGAAAAATTACTTACTACGTATGTGCAATGATCTCCTAAGAAGATTGT CTAAATCCCAGAATACAGTCTTCTGTGGACGGATTCAGCTCTTTTTGGCCAGGCTTTTCCCTCTGTCTGAGAAATCAGGTCTTAACTTGC AGAGTCAGTTTAATCTGGAAAATGTCACTGTTTTCAATACAAATGAGCAGGAAAGCACCCTGGGTCAGAAGCACACTGAAGATAGAGAAG AAGGAATGGATGTAGAAGAAGGCGAAATGGGAGACGAGGAAGCTCCAACAACGTGTGATATGGGAGAACCAAATCGTCATCCAAGCATGT TTCTCTTACTTTTGGTGTTGGAGAGACTCTACGCTTCCCCGATGGATGGTACTTCTTCTGCTCTCAGCATGGGACCTTTTGTTCCCTTCA TTATGAGGTGTGGTCACTCACCTGTCTACCACTCCCGTGAAATGGCAGCTCGTGCCTTGGTCCCATTTGTTATGATAGATCACATTCCTA ATACCATTCGAACTCTGTTGTCCACACTCCCCAGCTGCACTGACCAGTGTTTCCGGCAAAACCACATTCATGGGACACTTCTCCAGGTTT TTCATTTGTTGCAAGCCTACTCAGACTCCAAACACGGAACGAATTCAGACTTCCAGCACGAGCTGACTGACATCACTGTTTGTACCAAAG CCAAACTCTGGCTGGCCAAGAGGCAAAATCCATGTTTGGTGACCAGAGCTGTATATATTGATATTCTCTTCCTATTGACTTGCTGCCTCA ACAGATCTGCAAAGGACAACCAGCCAGTTCTGGAGAGTCTTGGCTTCTGGGAGGAAGTCAGAGGGATTATCTCAGGATCAGAGCTGATAA CGGGATTCCCTTGGGCCTTCAAGGTGCCAGGCCTGCCCCAGTACCTCCAGAGCCTCACCAGACTAGCCATTGCTGCAGTGTGGGCCGCGG CAGCCAAGAGTGGAGAGCGGGAGACGAATGTCCCCATCTCTTTCTCTCAGCTGTTAGAATCTGCCTTCCCTGAAGTGCGCTCACTAACAC TGGAAGCCCTCTTGGAAAAGTTCTTAGCAGCAGCCTCTGGACTTGGAGAGAAGGGCGTGCCACCCTTGCTGTGCAACATGGGAGAGAAGT TCTTATTGTTGGCCATGAAGGAAAATCACCCAGAATGCTTCTGCAAGATACTGAAAATTCTCCACTGCATGGACCCTGGTGAGTGGCTTC CCCAGACGGAGCACTGTGTCCATCTGACCCCAAAGGAGTTCTTGATCTGGACGATGGATATTGCTTCCAATGAAAGATCTGAAATTCAGA GTGTAGCTCTGAGACTTGCTTCCAAAGTCATTTCCCACCACATGCAGACATGTGTGGAGAACAGGGAATTGATAGCTGCTGAGCTGAAGC AGTGGGTTCAGCTGGTCATCTTGTCATGTGAAGACCATCTTCCTACAGAGTCTAGGCTGGCCGTCGTTGAAGTCCTCACCAGTACTACAC CACTTTTCCTCACCAACCCCCATCCTATTCTTGAGTTGCAGGATACACTTGCTCTCTGGAAGTGTGTCCTTACCCTTCTGCAGAGTGAGG AGCAAGCTGTTAGAGATGCAGCCACGGAAACCGTGACAACTGCCATGTCACAAGAAAATACCTGCCAGTCAACAGAGTTTGCCTTCTGCC AGGTGGATGCCTCCATCGCTCTGGCCCTGGCCCTGGCCGTCCTGTGTGATCTGCTCCAGCAGTGGGACCAGTTGGCCCCTGGACTGCCCA TCCTGCTGGGATGGCTGTTGGGAGAGAGTGATGACCTCGTGGCCTGTGTGGAGAGCATGCATCAGGTGGAAGAAGACTACCTGTTTGAAA AAGCAGAAGTCAACTTTTGGGCCGAGACCCTGATCTTTGTGAAATACCTCTGCAAGCACCTCTTCTGTCTCCTCTCAAAGTCCGGCTGGC GTCCCCCAAGCCCTGAGATGCTCTGTCACCTTCAAAGGATGGTGTCAGAGCAGTGCCACCTCCTGTCTCAGTTCTTCAGAGAGCTTCCAC CAGCTGCTGAGTTTGTGAAGACAGTGGAGTTCACAAGACTACGCATTCAAGAGGAAAGGACTTTGGCTTGCTTGAGGCTGCTGGCCTTTT TGGAAGGAAAGGAAGGGGAAGACACCCTAGTTCTCAGTGTTTGGGACTCTTATGCAGAATCGAGGCAGTTAACTCTTCCAAGAACAGAAG CGGCATGTTGAAGAAAATCTGGGGGATTGGGATGGGGGTATGTGTGGATTTTTCCTCCACTAAATCTGCAGGAAACATGTTGAACATAAA |
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FusionGenePPI for THOC1_THADA |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| THOC1 | RB1, DDX39B, ALYREF, THOC2, THOC5, NCBP1, THOC3, THOC7, THOC6, IK, SF3B2, SF3B1, ZCCHC8, UTRN, ZC3H15, UBR7, RRP9, XPO4, VPS53, TRMT112, TPM3, TPM1, USP13, ZNF830, DHX8, THOC1, FRA10AC1, SAP30BP, WDR77, RPA3, RPA2, RPA1, RABGEF1, TRIM54, MOAP1, USHBP1, OBSL1, RNF2, LUZP4, DSCC1, KRAS, ADAR, DHX9, FMR1, GSN, PRMT1, SP110, NFKBIL1, FXR1, DUSP11, TOP3B, BCLAF1, EIF4A3, ZC3H11A, THRAP3, C17orf85, DDX39A, KIF1C, B4GALT7, ZC3H13, ZZEF1, ZC3H3, CHTOP, RBM15B, MRPS17, GTSE1, C14orf166, RBM27, BCCIP, SCAF1, ZC3H14, CAAP1, TDRD3, FYTTD1, POLDIP3, SARNP, PWWP2A, ATG4A, TARSL2, C19orf47, RBM33, ZFC3H1, C15orf52, NEDD4, MRPL12, MTNR1B, DLST, PDHA1 | THADA | CUL3, UBA2, AHCYL1, SRXN1, SSSCA1, SEC24A, SEC23A, SULT1A1, NUBP2, STAM, IGBP1, PSAT1, SIN3A, TES, EGFR, USHBP1, CD274, VSIG2, CA14, LYPD3, SCN2B, ALDH3A2, NTRK1, VASN, TMEM206, TNFRSF1A, OPRM1, SIGLECL1, CHRM4, FZD10, ILVBL, EDNRB, NAA10, CCKBR, CD83, APLNR, MLST8, MTOR, XPO6, XPO4 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for THOC1_THADA |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for THOC1_THADA |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | THADA | C0011860 | Diabetes Mellitus, Non-Insulin-Dependent | 1 | CTD_human |
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