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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 37600

FusionGeneSummary for TCF7L2_ATP5G3

check button Fusion gene summary
Fusion gene informationFusion gene name: TCF7L2_ATP5G3
Fusion gene ID: 37600
HgeneTgene
Gene symbol

TCF7L2

ATP5G3

Gene ID

6934

Gene nametranscription factor 7 like 2
SynonymsTCF-4|TCF4
Cytomap

10q25.2-q25.3

Type of geneprotein-coding
Descriptiontranscription factor 7-like 2HMG box transcription factor 4T-cell factor 4T-cell-specific transcription factor 4hTCF-4transcription factor 7-like 2 (T-cell specific, HMG-box)
Modification date20180527
UniProtAcc

Q9NQB0

Ensembl transtripts involved in fusion geneENST00000534894, ENST00000536810, 
ENST00000545257, ENST00000355995, 
ENST00000543371, ENST00000355717, 
ENST00000538897, ENST00000349937, 
ENST00000369397, ENST00000352065, 
ENST00000369395, ENST00000542695, 
ENST00000369389, ENST00000369386, 
ENST00000466338, 
ENST00000284727, 
ENST00000409194, ENST00000392541, 
Fusion gene scores* DoF score9 X 7 X 10=6307 X 4 X 5=140
# samples 157
** MAII scorelog2(15/630*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(7/140*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: TCF7L2 [Title/Abstract] AND ATP5G3 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneTCF7L2

GO:0000122

negative regulation of transcription by RNA polymerase II

12799378

HgeneTCF7L2

GO:0006357

regulation of transcription by RNA polymerase II

9727977

HgeneTCF7L2

GO:0032092

positive regulation of protein binding

12799378

HgeneTCF7L2

GO:0032350

regulation of hormone metabolic process

15525634

HgeneTCF7L2

GO:0042593

glucose homeostasis

15525634

HgeneTCF7L2

GO:0043433

negative regulation of DNA binding transcription factor activity

12799378

HgeneTCF7L2

GO:0045444

fat cell differentiation

10937998

HgeneTCF7L2

GO:0045892

negative regulation of transcription, DNA-templated

12799378|15525634

HgeneTCF7L2

GO:0045944

positive regulation of transcription by RNA polymerase II

9065401|19168596

HgeneTCF7L2

GO:0048625

myoblast fate commitment

10937998


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1BF814890TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000534894ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000534894ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000534894ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000536810ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000536810ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000536810ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000545257ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000545257ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000545257ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000355995ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000355995ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000355995ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000543371ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000543371ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000543371ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000355717ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000355717ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000355717ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000538897ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000538897ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000538897ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000349937ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000349937ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000349937ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000369397ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000369397ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000369397ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000352065ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000352065ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000352065ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000369395ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000369395ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
In-frameENST00000369395ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
5UTR-3CDSENST00000542695ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
5UTR-3CDSENST00000542695ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
5UTR-3CDSENST00000542695ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
intron-3CDSENST00000369389ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
intron-3CDSENST00000369389ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
intron-3CDSENST00000369389ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
intron-3CDSENST00000369386ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
intron-3CDSENST00000369386ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
intron-3CDSENST00000369386ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
intron-3CDSENST00000466338ENST00000284727TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
intron-3CDSENST00000466338ENST00000409194TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-
intron-3CDSENST00000466338ENST00000392541TCF7L2chr10

114799837

-ATP5G3chr2

176043929

-

Top

FusionProtFeatures for TCF7L2_ATP5G3


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
TCF7L2

Q9NQB0

ATP5G3

Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for TCF7L2_ATP5G3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_TCF7L2_ENST00000534894_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000534894_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000534894_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000536810_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000536810_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000536810_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000545257_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000545257_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000545257_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000355995_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000355995_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000355995_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000543371_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000543371_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000543371_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000355717_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000355717_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000355717_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000538897_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000538897_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000538897_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000349937_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000349937_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000349937_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000369397_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000369397_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000369397_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000352065_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000352065_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000352065_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000369395_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000369395_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0aa

>In-frame_TCF7L2_ENST00000369395_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0aa


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_TCF7L2_ENST00000534894_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000534894_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000534894_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000536810_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000536810_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000536810_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000545257_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000545257_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000545257_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000355995_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000355995_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000355995_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000543371_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000543371_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000543371_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000355717_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000355717_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000355717_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000538897_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000538897_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000538897_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000349937_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000349937_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000349937_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000369397_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000369397_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000369397_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000352065_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000352065_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000352065_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000369395_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000369395_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000369395_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt


* Fusion transcript sequences (Full-length transcript).
>In-frame_TCF7L2_ENST00000534894_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000534894_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000534894_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000536810_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000536810_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000536810_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000545257_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000545257_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000545257_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000355995_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000355995_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000355995_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000543371_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000543371_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000543371_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000355717_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000355717_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000355717_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000538897_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000538897_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000538897_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000349937_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000349937_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000349937_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000369397_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000369397_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000369397_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000352065_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000352065_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000352065_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000369395_chr10_114799837_-_ATP5G3_ENST00000284727_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000369395_chr10_114799837_-_ATP5G3_ENST00000409194_chr2_176043929_-_0nt

>In-frame_TCF7L2_ENST00000369395_chr10_114799837_-_ATP5G3_ENST00000392541_chr2_176043929_-_0nt


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FusionGenePPI for TCF7L2_ATP5G3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for TCF7L2_ATP5G3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for TCF7L2_ATP5G3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneTCF7L2C0036341Schizophrenia4PSYGENET
HgeneTCF7L2C0009404Colorectal Neoplasms2CTD_human
HgeneTCF7L2C0011860Diabetes Mellitus, Non-Insulin-Dependent2CTD_human
HgeneTCF7L2C0001418Adenocarcinoma1CTD_human
HgeneTCF7L2C0005586Bipolar Disorder1PSYGENET
HgeneTCF7L2C0009375Colonic Neoplasms1CTD_human
HgeneTCF7L2C0020507Hyperplasia1CTD_human
HgeneTCF7L2C0036337Schizoaffective Disorder1PSYGENET
HgeneTCF7L2C3495559Juvenile arthritis1CTD_human