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Fusion gene ID: 3706 |
FusionGeneSummary for B3GALTL_MTUS2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: B3GALTL_MTUS2 | Fusion gene ID: 3706 | Hgene | Tgene | Gene symbol | B3GALTL | MTUS2 | Gene ID | 145173 | 23281 |
| Gene name | beta 3-glucosyltransferase | microtubule associated scaffold protein 2 | |
| Synonyms | B3GALTL|B3GTL|B3Glc-T|Gal-T|beta3Glc-T | CAZIP|ICIS|KIAA0774|TIP150 | |
| Cytomap | 13q12.3 | 13q12.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | beta-1,3-glucosyltransferaseUDP-GAL:beta-GlcNAc beta-1,3-galactosyltransferase-likebeta 1,3-galactosyltransferase-likebeta 3-glycosyltransferase-like | microtubule-associated tumor suppressor candidate 2+TIP of 150 kDacardiac zipper proteinmicrotubule associated tumor suppressor candidate 2microtubule plus-end tracking protein TIP150tracking protein of 150 kDa | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q5JR59 | ||
| Ensembl transtripts involved in fusion gene | ENST00000343307, ENST00000461652, | ENST00000431530, ENST00000380808, ENST00000542829, ENST00000400542, | |
| Fusion gene scores | * DoF score | 3 X 2 X 2=12 | 6 X 5 X 2=60 |
| # samples | 3 | 6 | |
| ** MAII score | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(6/60*10)=0 | |
| Context | PubMed: B3GALTL [Title/Abstract] AND MTUS2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-BH-A0HB-01A | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000343307 | ENST00000431530 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| In-frame | ENST00000343307 | ENST00000380808 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| 5CDS-intron | ENST00000343307 | ENST00000542829 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| 5CDS-intron | ENST00000343307 | ENST00000400542 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| intron-3CDS | ENST00000461652 | ENST00000431530 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| intron-3CDS | ENST00000461652 | ENST00000380808 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| intron-intron | ENST00000461652 | ENST00000542829 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
| intron-intron | ENST00000461652 | ENST00000400542 | B3GALTL | chr13 | 31898032 | + | MTUS2 | chr13 | 30014120 | + |
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FusionProtFeatures for B3GALTL_MTUS2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| B3GALTL | MTUS2 |
| Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269|PubMed:10224141, ECO:0000269|PubMed:28301481}. | Binds microtubules. Together with MAPRE1 may target themicrotubule depolymerase KIF2C to the plus-end of microtubules.May regulate the dynamics of microtubules at their growing distaltip. {ECO:0000269|PubMed:19543227}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | B3GALTL | chr13:31898032 | chr13:30014120 | ENST00000343307 | + | 14 | 15 | 1_6 | 443 | 499 | Topological domain | Cytoplasmic |
| Hgene | B3GALTL | chr13:31898032 | chr13:30014120 | ENST00000343307 | + | 14 | 15 | 7_27 | 443 | 499 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
| Tgene | >MTUS2 | chr13:31898032 | chr13:30014120 | ENST00000380808 | + | 0 | 9 | 991_1335 | 18 | 349 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >MTUS2 | chr13:31898032 | chr13:30014120 | ENST00000542829 | + | 0 | 8 | 991_1335 | -113 | 259 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >MTUS2 | chr13:31898032 | chr13:30014120 | ENST00000380808 | + | 0 | 9 | 801_1150 | 18 | 349 | Region | Note=Localization to the growing distal tip of microtubules |
| Tgene | >MTUS2 | chr13:31898032 | chr13:30014120 | ENST00000542829 | + | 0 | 8 | 801_1150 | -113 | 259 | Region | Note=Localization to the growing distal tip of microtubules |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >B3GALTL | chr13:31898032 | chr13:30014120 | ENST00000343307 | + | 14 | 15 | 28_498 | 443 | 499 | Topological domain | Lumenal |
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FusionGeneSequence for B3GALTL_MTUS2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_B3GALTL_ENST00000343307_chr13_31898032_+_MTUS2_ENST00000431530_chr13_30014120_+_774aa MRPPACWWLLAPPALLALLTCSLAFGLASEDTKKEVKQSQDLEKSGISRKNDIDLKGIVFVIQSQSNSFHAKRAEQLKKSILKQAADLTQ ELPSVLLLHQLAKQEGAWTILPLLPHFSVTYSRNSSWIFFCEEETRIQIPKLLETLRRYDPSKEWFLGKALHDEEATIIHHYAFSENPTV FKYPDFAAGWALSIPLVNKLTKRLKSESLKSDFTIDLKHEIALYIWDKGGGPPLTPVPEFCTNDVDFYCATTFHSFLPLCRKPVKKKDIF VAVKTCKKFHGDRIPIVKQTWESQASLIEYYSDYTENSIPTVDLGIPNTDRGHCGKTFAILERFLNRSQDKTAWLVIVDDDTLISISRLQ HLLSCYDSGEPVFLGERYGYGLGTGGYSYITGGGGMVFSREAVRRLLASKCRCYSNDAPDDMVLGMCFSGLGIPVTHSPLFHQNESALVK EKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVED LTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLE IALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKET >In-frame_B3GALTL_ENST00000343307_chr13_31898032_+_MTUS2_ENST00000380808_chr13_30014120_+_774aa MRPPACWWLLAPPALLALLTCSLAFGLASEDTKKEVKQSQDLEKSGISRKNDIDLKGIVFVIQSQSNSFHAKRAEQLKKSILKQAADLTQ ELPSVLLLHQLAKQEGAWTILPLLPHFSVTYSRNSSWIFFCEEETRIQIPKLLETLRRYDPSKEWFLGKALHDEEATIIHHYAFSENPTV FKYPDFAAGWALSIPLVNKLTKRLKSESLKSDFTIDLKHEIALYIWDKGGGPPLTPVPEFCTNDVDFYCATTFHSFLPLCRKPVKKKDIF VAVKTCKKFHGDRIPIVKQTWESQASLIEYYSDYTENSIPTVDLGIPNTDRGHCGKTFAILERFLNRSQDKTAWLVIVDDDTLISISRLQ HLLSCYDSGEPVFLGERYGYGLGTGGYSYITGGGGMVFSREAVRRLLASKCRCYSNDAPDDMVLGMCFSGLGIPVTHSPLFHQNESALVK EKELSIELANIRDEVAFHTAKCEKLQKEKEELERRFEDEVKRLGWQQQAELQELEERLQLQFEAEMARLQEEHGDQLLSIRCQHQEQVED LTASHDAALLEMENNHTVAITILQDDHDHKVQELMSTHELEKKELEENFEKLRLSLQDQVDTLTFQSQSLRDRARRFEEALRKNTEEQLE IALAPYQHLEEDMKSLKQVLEMKNQQIHEQEKKILELEKLAEKNIILEEKIQVLQQQNEDLKARIDQNTVVTRQLSEENANLQEYVEKET |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_B3GALTL_ENST00000343307_chr13_31898032_+_MTUS2_ENST00000431530_chr13_30014120_+_2322nt ATGCGGCCGCCCGCCTGCTGGTGGCTGCTCGCGCCGCCGGCGCTGCTCGCGCTCCTCACCTGCTCCCTGGCTTTTGGTTTGGCTTCTGAA GATACAAAGAAAGAGGTCAAGCAGTCTCAGGATTTGGAGAAAAGTGGTATATCAAGGAAAAATGACATAGACTTAAAAGGAATTGTATTC GTCATCCAGAGTCAAAGTAATTCTTTTCATGCAAAGAGAGCAGAGCAGTTAAAAAAAAGCATCTTAAAGCAGGCTGCAGATCTTACACAG GAGCTCCCCAGTGTCCTCCTCCTTCATCAGCTGGCTAAACAAGAAGGTGCATGGACCATACTTCCGTTGTTACCGCATTTTTCTGTAACA TATAGCAGAAATTCATCTTGGATTTTCTTCTGTGAAGAAGAGACAAGAATACAGATTCCAAAACTCTTGGAAACCCTCAGAAGATATGAC CCCTCTAAGGAATGGTTTTTGGGAAAAGCATTACATGATGAAGAAGCTACAATAATTCACCATTATGCCTTTTCCGAGAATCCTACAGTT TTTAAGTATCCAGACTTTGCTGCAGGCTGGGCCTTAAGTATTCCACTTGTAAACAAGCTTACCAAGAGACTAAAGAGTGAATCCTTGAAA TCCGACTTTACAATAGATTTAAAACATGAGATTGCCCTCTACATCTGGGACAAAGGCGGAGGACCTCCCCTGACCCCAGTGCCTGAGTTT TGTACCAATGACGTGGACTTCTACTGTGCTACCACATTCCATTCTTTTCTACCGCTTTGTAGAAAGCCAGTGAAGAAGAAGGATATTTTT GTTGCAGTAAAAACATGCAAGAAATTTCATGGTGACAGAATACCTATTGTTAAGCAGACTTGGGAGAGCCAGGCAAGTCTCATTGAATAC TATAGTGACTATACTGAAAATTCCATTCCTACTGTGGATTTGGGAATTCCTAATACAGATAGAGGTCATTGTGGAAAGACATTTGCCATT TTGGAAAGATTTCTGAATCGTAGCCAGGACAAAACAGCATGGTTAGTCATTGTGGATGATGATACATTAATAAGTATCTCCAGGCTCCAG CACTTGCTTAGCTGTTATGACTCCGGCGAGCCTGTGTTTCTGGGAGAGCGCTACGGCTACGGCCTGGGCACTGGTGGCTACAGCTACATC ACGGGAGGAGGAGGAATGGTCTTCAGCAGAGAAGCCGTCAGGAGACTTCTCGCCAGTAAATGTCGATGCTACAGCAATGATGCTCCCGAT GATATGGTCCTGGGAATGTGCTTTAGTGGCTTGGGAATCCCTGTGACACACAGCCCTCTCTTCCATCAGAATGAAAGTGCCCTTGTGAAA GAAAAAGAGCTGTCAATCGAACTTGCAAACATCAGGGATGAAGTTGCCTTCCATACAGCAAAGTGCGAGAAACTACAAAAGGAGAAGGAG GAGCTGGAGAGGCGGTTCGAGGACGAGGTGAAGAGGCTGGGCTGGCAGCAGCAGGCCGAGCTCCAGGAGCTGGAGGAGCGGCTGCAGCTG CAATTCGAGGCGGAAATGGCGCGCCTGCAGGAGGAGCACGGTGACCAGCTGCTGAGCATCCGGTGTCAACACCAGGAGCAGGTGGAAGAT CTCACCGCCAGCCATGATGCTGCTCTCCTAGAGATGGAAAATAACCACACAGTTGCCATCACAATCCTGCAGGATGACCACGACCACAAA GTCCAAGAATTGATGTCCACTCATGAGCTTGAAAAGAAAGAATTGGAAGAAAATTTTGAAAAACTGCGGCTGTCATTGCAGGACCAGGTG GACACGCTGACCTTCCAGAGCCAGTCTCTGCGGGACAGAGCCCGCCGCTTCGAAGAGGCCTTGAGGAAGAACACAGAGGAGCAGCTGGAG ATTGCATTGGCTCCTTATCAGCACTTGGAAGAAGACATGAAGAGTCTGAAGCAGGTATTAGAAATGAAGAATCAGCAAATACACGAGCAA GAAAAGAAGATTCTTGAGCTGGAAAAGCTGGCAGAAAAGAACATTATCCTAGAAGAAAAGATCCAGGTTCTCCAACAGCAGAACGAAGAC CTCAAAGCAAGGATTGACCAAAACACAGTTGTCACCAGACAGCTGTCGGAGGAAAATGCTAACCTCCAGGAATATGTTGAGAAGGAAACC CAGGAGAAGAAGAGATTGAGCCGAACCAATGAAGAGCTGCTTTGGAAGCTCCAAACTGGGGACCCGACCAGTCCGATTAAACTCTCGCCC >In-frame_B3GALTL_ENST00000343307_chr13_31898032_+_MTUS2_ENST00000380808_chr13_30014120_+_2322nt ATGCGGCCGCCCGCCTGCTGGTGGCTGCTCGCGCCGCCGGCGCTGCTCGCGCTCCTCACCTGCTCCCTGGCTTTTGGTTTGGCTTCTGAA GATACAAAGAAAGAGGTCAAGCAGTCTCAGGATTTGGAGAAAAGTGGTATATCAAGGAAAAATGACATAGACTTAAAAGGAATTGTATTC GTCATCCAGAGTCAAAGTAATTCTTTTCATGCAAAGAGAGCAGAGCAGTTAAAAAAAAGCATCTTAAAGCAGGCTGCAGATCTTACACAG GAGCTCCCCAGTGTCCTCCTCCTTCATCAGCTGGCTAAACAAGAAGGTGCATGGACCATACTTCCGTTGTTACCGCATTTTTCTGTAACA TATAGCAGAAATTCATCTTGGATTTTCTTCTGTGAAGAAGAGACAAGAATACAGATTCCAAAACTCTTGGAAACCCTCAGAAGATATGAC CCCTCTAAGGAATGGTTTTTGGGAAAAGCATTACATGATGAAGAAGCTACAATAATTCACCATTATGCCTTTTCCGAGAATCCTACAGTT TTTAAGTATCCAGACTTTGCTGCAGGCTGGGCCTTAAGTATTCCACTTGTAAACAAGCTTACCAAGAGACTAAAGAGTGAATCCTTGAAA TCCGACTTTACAATAGATTTAAAACATGAGATTGCCCTCTACATCTGGGACAAAGGCGGAGGACCTCCCCTGACCCCAGTGCCTGAGTTT TGTACCAATGACGTGGACTTCTACTGTGCTACCACATTCCATTCTTTTCTACCGCTTTGTAGAAAGCCAGTGAAGAAGAAGGATATTTTT GTTGCAGTAAAAACATGCAAGAAATTTCATGGTGACAGAATACCTATTGTTAAGCAGACTTGGGAGAGCCAGGCAAGTCTCATTGAATAC TATAGTGACTATACTGAAAATTCCATTCCTACTGTGGATTTGGGAATTCCTAATACAGATAGAGGTCATTGTGGAAAGACATTTGCCATT TTGGAAAGATTTCTGAATCGTAGCCAGGACAAAACAGCATGGTTAGTCATTGTGGATGATGATACATTAATAAGTATCTCCAGGCTCCAG CACTTGCTTAGCTGTTATGACTCCGGCGAGCCTGTGTTTCTGGGAGAGCGCTACGGCTACGGCCTGGGCACTGGTGGCTACAGCTACATC ACGGGAGGAGGAGGAATGGTCTTCAGCAGAGAAGCCGTCAGGAGACTTCTCGCCAGTAAATGTCGATGCTACAGCAATGATGCTCCCGAT GATATGGTCCTGGGAATGTGCTTTAGTGGCTTGGGAATCCCTGTGACACACAGCCCTCTCTTCCATCAGAATGAAAGTGCCCTTGTGAAA GAAAAAGAGCTGTCAATCGAACTTGCAAACATCAGGGATGAAGTTGCCTTCCATACAGCAAAGTGCGAGAAACTACAAAAGGAGAAGGAG GAGCTGGAGAGGCGGTTCGAGGACGAGGTGAAGAGGCTGGGCTGGCAGCAGCAGGCCGAGCTCCAGGAGCTGGAGGAGCGGCTGCAGCTG CAATTCGAGGCGGAAATGGCGCGCCTGCAGGAGGAGCACGGTGACCAGCTGCTGAGCATCCGGTGTCAACACCAGGAGCAGGTGGAAGAT CTCACCGCCAGCCATGATGCTGCTCTCCTAGAGATGGAAAATAACCACACAGTTGCCATCACAATCCTGCAGGATGACCACGACCACAAA GTCCAAGAATTGATGTCCACTCATGAGCTTGAAAAGAAAGAATTGGAAGAAAATTTTGAAAAACTGCGGCTGTCATTGCAGGACCAGGTG GACACGCTGACCTTCCAGAGCCAGTCTCTGCGGGACAGAGCCCGCCGCTTCGAAGAGGCCTTGAGGAAGAACACAGAGGAGCAGCTGGAG ATTGCATTGGCTCCTTATCAGCACTTGGAAGAAGACATGAAGAGTCTGAAGCAGGTATTAGAAATGAAGAATCAGCAAATACACGAGCAA GAAAAGAAGATTCTTGAGCTGGAAAAGCTGGCAGAAAAGAACATTATCCTAGAAGAAAAGATCCAGGTTCTCCAACAGCAGAACGAAGAC CTCAAAGCAAGGATTGACCAAAACACAGTTGTCACCAGACAGCTGTCGGAGGAAAATGCTAACCTCCAGGAATATGTTGAGAAGGAAACC CAGGAGAAGAAGAGATTGAGCCGAACCAATGAAGAGCTGCTTTGGAAGCTCCAAACTGGGGACCCGACCAGTCCGATTAAACTCTCGCCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_B3GALTL_ENST00000343307_chr13_31898032_+_MTUS2_ENST00000431530_chr13_30014120_+_3020nt CGATGGCGCGGCGGAGACGGAGGGAGGAGGGGAGCCGGCAGAGAAGGGTCAGCCGCGGCGGCAGGGCGGCGGCGGCAGCGGCGCAGCTCC GCTCCCCGCGCGTCTCCCTTCCCCGCGCCCAGGTAGGGCGCTCAGCCTCCGCCGCCAGGATGCGGCCGCCCGCCTGCTGGTGGCTGCTCG CGCCGCCGGCGCTGCTCGCGCTCCTCACCTGCTCCCTGGCTTTTGGTTTGGCTTCTGAAGATACAAAGAAAGAGGTCAAGCAGTCTCAGG ATTTGGAGAAAAGTGGTATATCAAGGAAAAATGACATAGACTTAAAAGGAATTGTATTCGTCATCCAGAGTCAAAGTAATTCTTTTCATG CAAAGAGAGCAGAGCAGTTAAAAAAAAGCATCTTAAAGCAGGCTGCAGATCTTACACAGGAGCTCCCCAGTGTCCTCCTCCTTCATCAGC TGGCTAAACAAGAAGGTGCATGGACCATACTTCCGTTGTTACCGCATTTTTCTGTAACATATAGCAGAAATTCATCTTGGATTTTCTTCT GTGAAGAAGAGACAAGAATACAGATTCCAAAACTCTTGGAAACCCTCAGAAGATATGACCCCTCTAAGGAATGGTTTTTGGGAAAAGCAT TACATGATGAAGAAGCTACAATAATTCACCATTATGCCTTTTCCGAGAATCCTACAGTTTTTAAGTATCCAGACTTTGCTGCAGGCTGGG CCTTAAGTATTCCACTTGTAAACAAGCTTACCAAGAGACTAAAGAGTGAATCCTTGAAATCCGACTTTACAATAGATTTAAAACATGAGA TTGCCCTCTACATCTGGGACAAAGGCGGAGGACCTCCCCTGACCCCAGTGCCTGAGTTTTGTACCAATGACGTGGACTTCTACTGTGCTA CCACATTCCATTCTTTTCTACCGCTTTGTAGAAAGCCAGTGAAGAAGAAGGATATTTTTGTTGCAGTAAAAACATGCAAGAAATTTCATG GTGACAGAATACCTATTGTTAAGCAGACTTGGGAGAGCCAGGCAAGTCTCATTGAATACTATAGTGACTATACTGAAAATTCCATTCCTA CTGTGGATTTGGGAATTCCTAATACAGATAGAGGTCATTGTGGAAAGACATTTGCCATTTTGGAAAGATTTCTGAATCGTAGCCAGGACA AAACAGCATGGTTAGTCATTGTGGATGATGATACATTAATAAGTATCTCCAGGCTCCAGCACTTGCTTAGCTGTTATGACTCCGGCGAGC CTGTGTTTCTGGGAGAGCGCTACGGCTACGGCCTGGGCACTGGTGGCTACAGCTACATCACGGGAGGAGGAGGAATGGTCTTCAGCAGAG AAGCCGTCAGGAGACTTCTCGCCAGTAAATGTCGATGCTACAGCAATGATGCTCCCGATGATATGGTCCTGGGAATGTGCTTTAGTGGCT TGGGAATCCCTGTGACACACAGCCCTCTCTTCCATCAGAATGAAAGTGCCCTTGTGAAAGAAAAAGAGCTGTCAATCGAACTTGCAAACA TCAGGGATGAAGTTGCCTTCCATACAGCAAAGTGCGAGAAACTACAAAAGGAGAAGGAGGAGCTGGAGAGGCGGTTCGAGGACGAGGTGA AGAGGCTGGGCTGGCAGCAGCAGGCCGAGCTCCAGGAGCTGGAGGAGCGGCTGCAGCTGCAATTCGAGGCGGAAATGGCGCGCCTGCAGG AGGAGCACGGTGACCAGCTGCTGAGCATCCGGTGTCAACACCAGGAGCAGGTGGAAGATCTCACCGCCAGCCATGATGCTGCTCTCCTAG AGATGGAAAATAACCACACAGTTGCCATCACAATCCTGCAGGATGACCACGACCACAAAGTCCAAGAATTGATGTCCACTCATGAGCTTG AAAAGAAAGAATTGGAAGAAAATTTTGAAAAACTGCGGCTGTCATTGCAGGACCAGGTGGACACGCTGACCTTCCAGAGCCAGTCTCTGC GGGACAGAGCCCGCCGCTTCGAAGAGGCCTTGAGGAAGAACACAGAGGAGCAGCTGGAGATTGCATTGGCTCCTTATCAGCACTTGGAAG AAGACATGAAGAGTCTGAAGCAGGTATTAGAAATGAAGAATCAGCAAATACACGAGCAAGAAAAGAAGATTCTTGAGCTGGAAAAGCTGG CAGAAAAGAACATTATCCTAGAAGAAAAGATCCAGGTTCTCCAACAGCAGAACGAAGACCTCAAAGCAAGGATTGACCAAAACACAGTTG TCACCAGACAGCTGTCGGAGGAAAATGCTAACCTCCAGGAATATGTTGAGAAGGAAACCCAGGAGAAGAAGAGATTGAGCCGAACCAATG AAGAGCTGCTTTGGAAGCTCCAAACTGGGGACCCGACCAGTCCGATTAAACTCTCGCCCACATCTCCCGTTTACCGCGGCTCCTCCTCGG GGCCCTCCTCTCCGGCCAGAGTCAGCACAACACCCAGATGACGCCACTACACGGCCTGCGGGAGCTCCGGCTTCTCGTCCTCCGGTCTCC ACCCTGAGGGAGCACCGACCCGGTGCCGCCGGAGCTGGCCCTGTGCGCATGCTCAGTAGCTGCGAATGCATCCTAGGCGCGTCCTCCTCT GATCCCCGTGTAAGACTGCCCTGGTGTCGGCACTTAGGAATGTGTAAATGGTAAAGTCTGATGTGCAAACGTTTTACCATAGTTAGAGCC AAAAGAAAGACACTTGCAATTGTTCTTGAGCAATGAACTTTCACTGCAGAATTTCAGGTTAGTTACAAAAAGCTCAGTTTTCAATATACA TTGAATAATCATTGTGTACTGCACCGATATGTGTGTATATTTAGATATACGTATATACACATGCTGCGGTTCTGAATTTCATTTTTTATA ACATGAAGTGCTGACATATTTTAGTGAAGGTCAGCAGTTTTCTAACTTGTGCCTAAGAATTATTGGGAAATGAAAATGCATTTCTATCTA >In-frame_B3GALTL_ENST00000343307_chr13_31898032_+_MTUS2_ENST00000380808_chr13_30014120_+_3001nt CGATGGCGCGGCGGAGACGGAGGGAGGAGGGGAGCCGGCAGAGAAGGGTCAGCCGCGGCGGCAGGGCGGCGGCGGCAGCGGCGCAGCTCC GCTCCCCGCGCGTCTCCCTTCCCCGCGCCCAGGTAGGGCGCTCAGCCTCCGCCGCCAGGATGCGGCCGCCCGCCTGCTGGTGGCTGCTCG CGCCGCCGGCGCTGCTCGCGCTCCTCACCTGCTCCCTGGCTTTTGGTTTGGCTTCTGAAGATACAAAGAAAGAGGTCAAGCAGTCTCAGG ATTTGGAGAAAAGTGGTATATCAAGGAAAAATGACATAGACTTAAAAGGAATTGTATTCGTCATCCAGAGTCAAAGTAATTCTTTTCATG CAAAGAGAGCAGAGCAGTTAAAAAAAAGCATCTTAAAGCAGGCTGCAGATCTTACACAGGAGCTCCCCAGTGTCCTCCTCCTTCATCAGC TGGCTAAACAAGAAGGTGCATGGACCATACTTCCGTTGTTACCGCATTTTTCTGTAACATATAGCAGAAATTCATCTTGGATTTTCTTCT GTGAAGAAGAGACAAGAATACAGATTCCAAAACTCTTGGAAACCCTCAGAAGATATGACCCCTCTAAGGAATGGTTTTTGGGAAAAGCAT TACATGATGAAGAAGCTACAATAATTCACCATTATGCCTTTTCCGAGAATCCTACAGTTTTTAAGTATCCAGACTTTGCTGCAGGCTGGG CCTTAAGTATTCCACTTGTAAACAAGCTTACCAAGAGACTAAAGAGTGAATCCTTGAAATCCGACTTTACAATAGATTTAAAACATGAGA TTGCCCTCTACATCTGGGACAAAGGCGGAGGACCTCCCCTGACCCCAGTGCCTGAGTTTTGTACCAATGACGTGGACTTCTACTGTGCTA CCACATTCCATTCTTTTCTACCGCTTTGTAGAAAGCCAGTGAAGAAGAAGGATATTTTTGTTGCAGTAAAAACATGCAAGAAATTTCATG GTGACAGAATACCTATTGTTAAGCAGACTTGGGAGAGCCAGGCAAGTCTCATTGAATACTATAGTGACTATACTGAAAATTCCATTCCTA CTGTGGATTTGGGAATTCCTAATACAGATAGAGGTCATTGTGGAAAGACATTTGCCATTTTGGAAAGATTTCTGAATCGTAGCCAGGACA AAACAGCATGGTTAGTCATTGTGGATGATGATACATTAATAAGTATCTCCAGGCTCCAGCACTTGCTTAGCTGTTATGACTCCGGCGAGC CTGTGTTTCTGGGAGAGCGCTACGGCTACGGCCTGGGCACTGGTGGCTACAGCTACATCACGGGAGGAGGAGGAATGGTCTTCAGCAGAG AAGCCGTCAGGAGACTTCTCGCCAGTAAATGTCGATGCTACAGCAATGATGCTCCCGATGATATGGTCCTGGGAATGTGCTTTAGTGGCT TGGGAATCCCTGTGACACACAGCCCTCTCTTCCATCAGAATGAAAGTGCCCTTGTGAAAGAAAAAGAGCTGTCAATCGAACTTGCAAACA TCAGGGATGAAGTTGCCTTCCATACAGCAAAGTGCGAGAAACTACAAAAGGAGAAGGAGGAGCTGGAGAGGCGGTTCGAGGACGAGGTGA AGAGGCTGGGCTGGCAGCAGCAGGCCGAGCTCCAGGAGCTGGAGGAGCGGCTGCAGCTGCAATTCGAGGCGGAAATGGCGCGCCTGCAGG AGGAGCACGGTGACCAGCTGCTGAGCATCCGGTGTCAACACCAGGAGCAGGTGGAAGATCTCACCGCCAGCCATGATGCTGCTCTCCTAG AGATGGAAAATAACCACACAGTTGCCATCACAATCCTGCAGGATGACCACGACCACAAAGTCCAAGAATTGATGTCCACTCATGAGCTTG AAAAGAAAGAATTGGAAGAAAATTTTGAAAAACTGCGGCTGTCATTGCAGGACCAGGTGGACACGCTGACCTTCCAGAGCCAGTCTCTGC GGGACAGAGCCCGCCGCTTCGAAGAGGCCTTGAGGAAGAACACAGAGGAGCAGCTGGAGATTGCATTGGCTCCTTATCAGCACTTGGAAG AAGACATGAAGAGTCTGAAGCAGGTATTAGAAATGAAGAATCAGCAAATACACGAGCAAGAAAAGAAGATTCTTGAGCTGGAAAAGCTGG CAGAAAAGAACATTATCCTAGAAGAAAAGATCCAGGTTCTCCAACAGCAGAACGAAGACCTCAAAGCAAGGATTGACCAAAACACAGTTG TCACCAGACAGCTGTCGGAGGAAAATGCTAACCTCCAGGAATATGTTGAGAAGGAAACCCAGGAGAAGAAGAGATTGAGCCGAACCAATG AAGAGCTGCTTTGGAAGCTCCAAACTGGGGACCCGACCAGTCCGATTAAACTCTCGCCCACATCTCCCGTTTACCGCGGCTCCTCCTCGG GGCCCTCCTCTCCGGCCAGAGTCAGCACAACACCCAGATGACGCCACTACACGGCCTGCGGGAGCTCCGGCTTCTCGTCCTCCGGTCTCC ACCCTGAGGGAGCACCGACCCGGTGCCGCCGGAGCTGGCCCTGTGCGCATGCTCAGTAGCTGCGAATGCATCCTAGGCGCGTCCTCCTCT GATCCCCGTGTAAGACTGCCCTGGTGTCGGCACTTAGGAATGTGTAAATGGTAAAGTCTGATGTGCAAACGTTTTACCATAGTTAGAGCC AAAAGAAAGACACTTGCAATTGTTCTTGAGCAATGAACTTTCACTGCAGAATTTCAGGTTAGTTACAAAAAGCTCAGTTTTCAATATACA TTGAATAATCATTGTGTACTGCACCGATATGTGTGTATATTTAGATATACGTATATACACATGCTGCGGTTCTGAATTTCATTTTTTATA ACATGAAGTGCTGACATATTTTAGTGAAGGTCAGCAGTTTTCTAACTTGTGCCTAAGAATTATTGGGAAATGAAAATGCATTTCTATCTA |
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FusionGenePPI for B3GALTL_MTUS2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| B3GALTL | ELAVL1, TAZ, IDS, ERBB3, TMEM25, PTCH1, PTPRK, AK1, EMC2, FGFR1OP, SMC6, PAPLN, CFP, THBS2, ADAMTSL1, ADAMTS18, ALPPL2, CTSE, C6 | MTUS2 | RIBC2, ZFP64, PLK4, ZNF655, C1orf216, KAT5, ITSN1, PSMA1, ARNT2, GTF2I, IQCE, KIF1A, NUBPL, AES, SLC25A6, AQP1, BMP7, BYSL, CRY2, CTSZ, DOCK2, DTNB, HCK, HSF2, ITGB5, LMO2, MAGEA8, MFAP1, ODF1, CDK18, PIN1, PKP2, PRKAA1, RAB3IL1, RGS2, RPA1, RPL9, CXCL11, SDCBP, SMARCE1, SNAI1, SNRPA, SNRPB2, SPG7, TAF13, ZNF3, ZNF20, ZNF136, ZSCAN26, ZNF224, ZNF232, NELFE, STK16, SCEL, CDK5R1, USP2, MTMR6, CREB5, PDE4DIP, ZSCAN12, HDAC4, DLGAP5, FCHSD2, SLC23A1, COG2, SNW1, TXN2, POLDIP2, PRPF31, ZNF337, AFF4, NDOR1, DCTN4, CDKL3, WAC, PPHLN1, ZNF581, C21orf58, CCHCR1, C1orf109, FBXO34, WDYHV1, FAM90A1, C14orf105, SETD5, C19orf66, LIMS2, ZNF415, PLSCR4, CBX8, ZNF490, ZNF624, TSHZ3, CCDC146, MARK4, ZNF410, CXCL16, ZNF250, DMRT3, SH2D4A, GAL3ST2, ROBO3, CERK, AEN, C20orf195, ZFYVE21, ZNF426, LENG1, CDC73, ZNF329, ZC2HC1C, FBXL18, ZFP2, THAP7, NDEL1, SLIRP, FAM161A, POLDIP3, LNX1, ZNF607, ZNF587, GTPBP10, ZNF439, CEP95, ZNF670, TP53RK, RHPN1, PTPMT1, HAUS1, C8orf34, CATSPER1, LRR1, ZNF440, SNHG11, ZNF572, SELM, CWF19L2, SPATA8, ZNF785, ZNF417, ZNF599, SYT6, DCDC2B, CCDC17, ALS2CR11, ZMAT2, LOC153684, SH3RF2, CCDC60, CCDC116, CDC20B, NUDT10, PPP1R18, ZFC3H1, FAM13C, ZBTB38, TSGA10IP, GOLGA2P11, ZNF844, FAM71E2, RTP5, LINC00636, CEP57L1, TRIM42, CATIP, LYSMD1, FAM74A4, MAPRE1, MTUS2, KIF2C, FHL3, TULP2, ZNF557, FAM110A, TFG, MTUS1, CCDC6, ATP11C, MYADM, TMEM63B, ATP6V0C, ATP6V0A2, DCAF10, MLLT4, RABL6, ATP6V0A1, MTDH, CD109, MACF1, DDX46, CCP110, SCAF8, EIF5B, FRA10AC1, FYN, ULBP2, PAG1, AP1B1, CAST, PAK4 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for B3GALTL_MTUS2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for B3GALTL_MTUS2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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