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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionGeneSequence

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Fusion gene ID: 36864

FusionGeneSummary for SYCP2_ZMYND8

check button Fusion gene summary
Fusion gene informationFusion gene name: SYCP2_ZMYND8
Fusion gene ID: 36864
HgeneTgene
Gene symbol

SYCP2

ZMYND8

Gene ID

10388

23613

Gene namesynaptonemal complex protein 2zinc finger MYND-type containing 8
SynonymsSCP-2|SCP2PRKCBP1|PRO2893|RACK7
Cytomap

20q13.33

20q13.12

Type of geneprotein-codingprotein-coding
Descriptionsynaptonemal complex protein 2synaptonemal complex lateral element proteinprotein kinase C-binding protein 1CTCL tumor antigen se14-3cutaneous T-cell lymphoma-associated antigen se14-3predicted protein of HQ2893zinc finger MYND domain-containing protein 8
Modification date2018051920180526
UniProtAcc

Q9BX26

Q9ULU4

Ensembl transtripts involved in fusion geneENST00000357552, ENST00000371001, 
ENST00000476314, 		ENST00000311275, 
ENST00000360911, ENST00000458360, 
ENST00000262975, ENST00000471951, 
ENST00000352431, ENST00000396281, 
ENST00000446994, ENST00000536340, 
ENST00000355972, ENST00000540497, 
ENST00000461685, ENST00000372023, 
ENST00000468376, 
Fusion gene scores* DoF score2 X 2 X 1=45 X 5 X 4=100
# samples 25
** MAII scorelog2(2/4*10)=2.32192809488736log2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SYCP2 [Title/Abstract] AND ZMYND8 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDBRCATCGA-A2-A0CT-01ASYCP2chr20

58467045

-ZMYND8chr20

45927691

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000357552ENST00000311275SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000357552ENST00000360911SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000357552ENST00000458360SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000357552ENST00000262975SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000357552ENST00000471951SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000357552ENST00000352431SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000357552ENST00000396281SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000357552ENST00000446994SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000357552ENST00000536340SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000357552ENST00000355972SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000357552ENST00000540497SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000357552ENST00000461685SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000357552ENST00000372023SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000357552ENST00000468376SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
Frame-shiftENST00000371001ENST00000311275SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000371001ENST00000360911SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000371001ENST00000458360SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000371001ENST00000262975SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000371001ENST00000471951SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000371001ENST00000352431SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000371001ENST00000396281SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000371001ENST00000446994SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000371001ENST00000536340SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000371001ENST00000355972SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000371001ENST00000540497SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000371001ENST00000461685SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000371001ENST00000372023SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
5CDS-intronENST00000371001ENST00000468376SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-3CDSENST00000476314ENST00000311275SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-intronENST00000476314ENST00000360911SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-intronENST00000476314ENST00000458360SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-intronENST00000476314ENST00000262975SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-intronENST00000476314ENST00000471951SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-intronENST00000476314ENST00000352431SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-intronENST00000476314ENST00000396281SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-intronENST00000476314ENST00000446994SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-intronENST00000476314ENST00000536340SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-intronENST00000476314ENST00000355972SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-intronENST00000476314ENST00000540497SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-intronENST00000476314ENST00000461685SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-intronENST00000476314ENST00000372023SYCP2chr20

58467045

-ZMYND8chr20

45927691

-
intron-intronENST00000476314ENST00000468376SYCP2chr20

58467045

-ZMYND8chr20

45927691

-

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FusionProtFeatures for SYCP2_ZMYND8


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SYCP2

Q9BX26

ZMYND8

Q9ULU4

Major component of the axial/lateral elements ofsynaptonemal complexes (SCS) during meiotic prophase. Plays a rolein the assembly of synaptonemal complexes. Required for normalmeiotic chromosome synapsis during oocyte and spermatocytedevelopment and for normal male and female fertility. Required forinsertion of SYCP3 into synaptonemal complexes. May be involved inthe organization of chromatin by temporarily binding to DNAscaffold attachment regions. Requires SYCP3, but not SYCP1, inorder to be incorporated into the axial/lateral elements.{ECO:0000250|UniProtKB:Q9CUU3}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSYCP2chr20:58467045chr20:45927691ENST00000357552-2445655_6607881531Compositional biasNote=Poly-Ser
HgeneSYCP2chr20:58467045chr20:45927691ENST00000371001-2344655_6607881531Compositional biasNote=Poly-Ser
TgeneZMYND8chr20:58467045chr20:45927691ENST00000262975-3241089_1092581169Compositional biasNote=Poly-Ser
TgeneZMYND8chr20:58467045chr20:45927691ENST00000262975-324838_854581169Compositional biasNote=Poly-Gln
TgeneZMYND8chr20:58467045chr20:45927691ENST00000311275-2221089_1092581187Compositional biasNote=Poly-Ser
TgeneZMYND8chr20:58467045chr20:45927691ENST00000311275-222838_854581187Compositional biasNote=Poly-Gln
TgeneZMYND8chr20:58467045chr20:45927691ENST00000352431-2221089_1092781161Compositional biasNote=Poly-Ser
TgeneZMYND8chr20:58467045chr20:45927691ENST00000352431-222838_854781161Compositional biasNote=Poly-Gln
TgeneZMYND8chr20:58467045chr20:45927691ENST00000355972-3241089_1092581215Compositional biasNote=Poly-Ser
TgeneZMYND8chr20:58467045chr20:45927691ENST00000355972-324838_854581215Compositional biasNote=Poly-Gln
TgeneZMYND8chr20:58467045chr20:45927691ENST00000360911-0221089_1092-121136Compositional biasNote=Poly-Ser
TgeneZMYND8chr20:58467045chr20:45927691ENST00000360911-02243_47-121136Compositional biasNote=Poly-Lys
TgeneZMYND8chr20:58467045chr20:45927691ENST00000360911-022838_854-121136Compositional biasNote=Poly-Gln
TgeneZMYND8chr20:58467045chr20:45927691ENST00000461685-2231089_1092781189Compositional biasNote=Poly-Ser
TgeneZMYND8chr20:58467045chr20:45927691ENST00000461685-223838_854781189Compositional biasNote=Poly-Gln
TgeneZMYND8chr20:58467045chr20:45927691ENST00000471951-2231089_1092781235Compositional biasNote=Poly-Ser
TgeneZMYND8chr20:58467045chr20:45927691ENST00000471951-223838_854781235Compositional biasNote=Poly-Gln
TgeneZMYND8chr20:58467045chr20:45927691ENST00000262975-324165_235581169DomainBromo
TgeneZMYND8chr20:58467045chr20:45927691ENST00000262975-324277_327581169DomainPWWP
TgeneZMYND8chr20:58467045chr20:45927691ENST00000311275-222165_235581187DomainBromo
TgeneZMYND8chr20:58467045chr20:45927691ENST00000311275-222277_327581187DomainPWWP
TgeneZMYND8chr20:58467045chr20:45927691ENST00000352431-222165_235781161DomainBromo
TgeneZMYND8chr20:58467045chr20:45927691ENST00000352431-222277_327781161DomainPWWP
TgeneZMYND8chr20:58467045chr20:45927691ENST00000355972-324165_235581215DomainBromo
TgeneZMYND8chr20:58467045chr20:45927691ENST00000355972-324277_327581215DomainPWWP
TgeneZMYND8chr20:58467045chr20:45927691ENST00000360911-022165_235-121136DomainBromo
TgeneZMYND8chr20:58467045chr20:45927691ENST00000360911-022277_327-121136DomainPWWP
TgeneZMYND8chr20:58467045chr20:45927691ENST00000461685-223165_235781189DomainBromo
TgeneZMYND8chr20:58467045chr20:45927691ENST00000461685-223277_327781189DomainPWWP
TgeneZMYND8chr20:58467045chr20:45927691ENST00000471951-223165_235781235DomainBromo
TgeneZMYND8chr20:58467045chr20:45927691ENST00000471951-223277_327781235DomainPWWP
TgeneZMYND8chr20:58467045chr20:45927691ENST00000262975-3241028_1062581169Zinc fingerMYND-type
TgeneZMYND8chr20:58467045chr20:45927691ENST00000262975-32488_133581169Zinc fingerPHD-type
TgeneZMYND8chr20:58467045chr20:45927691ENST00000311275-2221028_1062581187Zinc fingerMYND-type
TgeneZMYND8chr20:58467045chr20:45927691ENST00000311275-22288_133581187Zinc fingerPHD-type
TgeneZMYND8chr20:58467045chr20:45927691ENST00000352431-2221028_1062781161Zinc fingerMYND-type
TgeneZMYND8chr20:58467045chr20:45927691ENST00000352431-22288_133781161Zinc fingerPHD-type
TgeneZMYND8chr20:58467045chr20:45927691ENST00000355972-3241028_1062581215Zinc fingerMYND-type
TgeneZMYND8chr20:58467045chr20:45927691ENST00000355972-32488_133581215Zinc fingerPHD-type
TgeneZMYND8chr20:58467045chr20:45927691ENST00000360911-0221028_1062-121136Zinc fingerMYND-type
TgeneZMYND8chr20:58467045chr20:45927691ENST00000360911-02288_133-121136Zinc fingerPHD-type
TgeneZMYND8chr20:58467045chr20:45927691ENST00000461685-2231028_1062781189Zinc fingerMYND-type
TgeneZMYND8chr20:58467045chr20:45927691ENST00000461685-22388_133781189Zinc fingerPHD-type
TgeneZMYND8chr20:58467045chr20:45927691ENST00000471951-2231028_1062781235Zinc fingerMYND-type
TgeneZMYND8chr20:58467045chr20:45927691ENST00000471951-22388_133781235Zinc fingerPHD-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZMYND8chr20:58467045chr20:45927691ENST00000262975-32443_47581169Compositional biasNote=Poly-Lys
TgeneZMYND8chr20:58467045chr20:45927691ENST00000311275-22243_47581187Compositional biasNote=Poly-Lys
TgeneZMYND8chr20:58467045chr20:45927691ENST00000352431-22243_47781161Compositional biasNote=Poly-Lys
TgeneZMYND8chr20:58467045chr20:45927691ENST00000355972-32443_47581215Compositional biasNote=Poly-Lys
TgeneZMYND8chr20:58467045chr20:45927691ENST00000461685-22343_47781189Compositional biasNote=Poly-Lys
TgeneZMYND8chr20:58467045chr20:45927691ENST00000471951-22343_47781235Compositional biasNote=Poly-Lys


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FusionGeneSequence for SYCP2_ZMYND8


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_SYCP2_ENST00000357552_chr20_58467045_-_ZMYND8_ENST00000311275_chr20_45927691_-_1917aa
MPIRPDLQQLEKCIDDALRKNDFKPLKTLLQIDICEDVKIKCSKQFFHKVDNLICRELNKEDIHNVSAILVSVGRCGKNISVLGQAGLLT
MIKQGLIQKMVAWFEKSKDIIQSQGNSKDEAVLNMIEDLVDLLLVIHDVSDEGKKQVVESFVPRICSLVIDSRVNICIQQEIIKKMNAML
DKMPQDARKILSNQEMLILMSSMGERILDAGDYDLQVGIVEALCRMTTEKQRQELAHQWFSMDFIAKAFKRIKDSEFETDCRIFLNLVNG
MLGDKRRVFTFPCLSAFLDKYELQIPSDEKLEEFWIDFNLGSQTLSFYIAGDNDDHQWEAVTVPEEKVQIYSIEVRESKKLLTIILKNTV
KISKREGKELLLYFDASLEITNVTQKIFGATKHRESIRKQGISVAKTSLHILFDASGSQILVPESQISPVGEELVSLKEKSKSPKEFAKP
SKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFSNTSIPPRRRRIKPPLQMTSSAEKPSVSQTSENRVDNAASLK
SRSSEGRHRRDNIDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDNICGNKIHSKWACWTPVTNIELCNNQ
RASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVES
ETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMSELRHGPFYYMKQPLTTDPVDV
VPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGT
DAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYL
AACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYV
ENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSV
HTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK
ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDK
EGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSE
SELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVK
KQRPLLPKETAPAVQRVVWNSSSKFQTSSQKWHMQKMQRQQQQQQQQNQQQQPQSSQGTRYQTRQAVKAVQQKEITQSPSTSTITLVTST
QSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSE
MKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQ
QEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGS


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_SYCP2_ENST00000357552_chr20_58467045_-_ZMYND8_ENST00000311275_chr20_45927691_-_5751nt
ATGCCAATAAGACCAGATCTCCAGCAGTTGGAAAAATGCATTGATGATGCTTTAAGAAAAAATGATTTCAAACCTTTGAAAACACTTTTG
CAAATTGATATTTGTGAAGATGTGAAGATTAAATGCAGCAAACAGTTTTTCCACAAGGTGGACAACCTTATATGCAGGGAACTTAATAAA
GAGGATATCCACAATGTTTCAGCCATTTTGGTTTCTGTTGGAAGATGTGGCAAAAATATCAGTGTATTGGGGCAAGCTGGACTTCTAACG
ATGATAAAACAAGGACTAATACAAAAGATGGTTGCCTGGTTTGAAAAATCCAAGGACATTATTCAGAGTCAAGGAAATTCAAAAGATGAA
GCTGTTCTAAATATGATAGAAGACTTAGTTGATCTTCTGCTGGTCATACATGATGTCAGTGATGAAGGTAAAAAACAAGTAGTGGAAAGT
TTCGTACCTCGCATTTGTTCCCTGGTTATTGACTCAAGAGTGAATATTTGTATTCAGCAAGAGATTATAAAAAAAATGAATGCTATGCTT
GACAAAATGCCTCAAGATGCCCGGAAAATACTCTCTAACCAAGAAATGTTAATTCTCATGAGTAGTATGGGAGAAAGGATTTTAGATGCT
GGAGATTATGACTTACAGGTAGGCATTGTAGAAGCTTTGTGTAGAATGACCACAGAAAAACAAAGACAAGAACTGGCACATCAGTGGTTT
TCAATGGATTTTATTGCTAAGGCATTTAAAAGAATTAAGGACTCTGAATTTGAAACAGATTGCAGGATATTTCTCAACCTTGTAAATGGC
ATGCTTGGAGACAAAAGAAGGGTCTTTACATTTCCTTGTTTATCAGCATTTCTTGATAAATATGAGCTGCAAATACCATCAGATGAAAAA
CTTGAGGAATTTTGGATTGATTTTAATCTTGGGAGTCAGACTCTCTCATTCTACATTGCTGGAGATAATGATGATCATCAATGGGAAGCA
GTTACTGTGCCAGAGGAAAAAGTACAAATATACAGCATTGAAGTGAGAGAATCAAAGAAGCTACTGACAATAATTCTGAAAAATACAGTA
AAAATTAGCAAAAGAGAAGGGAAAGAATTGCTTTTGTATTTTGACGCATCACTAGAAATCACTAATGTAACTCAAAAAATTTTTGGTGCA
ACTAAACATAGGGAATCTATCAGAAAACAAGGTATTTCAGTTGCCAAAACGTCGCTGCATATACTTTTTGACGCAAGTGGATCACAGATT
CTAGTGCCAGAAAGTCAAATCTCACCAGTCGGAGAAGAGCTCGTTAGTTTAAAGGAAAAATCAAAGTCCCCAAAGGAATTTGCTAAACCT
TCAAAATATATCAAAAACAGTGACAAAGGGAATAGAAATAATAGTCAGCTTGAGAAAACTACTCCTAGCAAAAGAAAAATGTCTGAAGCA
TCAATGATTGTTTCTGGTGCAGATAGATACACTATGAGAAGTCCAGTGCTTTTCAGCAACACATCAATACCACCACGAAGAAGAAGAATT
AAACCACCACTGCAAATGACGAGCTCTGCAGAGAAACCTAGTGTTTCTCAAACATCAGAAAATAGAGTGGATAATGCTGCATCACTGAAA
TCTAGATCATCAGAAGGAAGACATAGAAGAGATAATATAGACAAACATATCAAAACTGCTAAGTGTGTAGAAAACACAGAAAATAAGAAT
GTTGAATTCCCAAACCAAAATTTTAGTGAACTCCAGGATGTTATACCAGATTCACAGGCAGCGGAAAAAAGAGATCATACTATATTACCT
GGTGTTTTAGACAACATCTGTGGAAATAAAATACACAGCAAATGGGCATGTTGGACACCTGTAACAAACATTGAACTATGTAATAACCAA
AGAGCAAGTACTTCGTCAGGAGACACATTGAATCAAGATATTGTTATAAATAAAAAACTTACTAAACAAAAATCATCCTCTTCAATATCT
GATCATAATTCTGAAGGAACAGGAAAAGTGAAATATAAGAAAGAACAAACCGACCATATCAAAATAGATAAAGCAGAAGTAGAAGTTTGC
AAGAAACACAATCAGCAACAAAATCATCCTAAATATTCAGGGCAGAAAAATACTGAAAATGCCAAGCAGAGTGATTGGCCTGTTGAATCT
GAAACTACTTTTAAATCGGTTCTCCTAAATAAGACAATTGAAGAATCGCTGATATATAGGAAGAAATACATATTGTCAAAAGATGTGAAT
ACTGCTACTTGCGATAAAAATCCATCTGCTAGCAAAAATGTGCAAAGTCATAGAAAAGCAGAGAAAGAATTGACTTCTGAGCTTAATTCC
TGGGATTCGAAACAAAAAAAAATGTCAGAACTAAGACATGGTCCGTTTTACTATATGAAGCAGCCACTCACCACAGACCCTGTTGATGTT
GTACCGCAGGATGGACGGAATGATTTCTACTGCTGGGTTTGTCACCGGGAAGGCCAAGTCCTTTGCTGTGAGCTCTGTCCCCGGGTTTAT
CACGCTAAGTGTCTGAGACTGACATCGGAACCAGAGGGGGACTGGTTTTGTCCTGAATGTGAGAAAATTACAGTAGCAGAATGCATCGAG
ACCCAGAGTAAAGCCATGACAATGCTCACCATTGAACAGTTATCCTACCTGCTCAAGTTTGCCATTCAGAAAATGAAACAGCCAGGGACA
GATGCATTCCAGAAGCCCGTTCCATTGGAACAGCACCCTGACTATGCGGAATACATCTTCCATCCAATGGACCTTTGTACATTGGAAAAG
AATGCGAAAAAGAAAATGTATGGCTGCACAGAAGCCTTCCTGGCTGATGCAAAGTGGATTTTGCACAACTGCATCATTTATAATGGGGGA
AATCACAAATTGACGCAAATAGCGAAAGTAGTCATCAAAATCTGTGAACATGAGATGAATGAAATCGAAGTATGTCCAGAATGTTATCTA
GCTGCTTGCCAAAAACGAGATAACTGGTTTTGTGAGCCTTGTAGCAATCCACATCCTTTGGTCTGGGCCAAACTGAAGGGGTTTCCATTC
TGGCCTGCAAAAGCTCTAAGGGATAAAGACGGGCAGGTCGATGCCCGATTCTTTGGACAACATGACAGGGCCTGGGTTCCAATAAATAAT
TGCTACCTCATGTCTAAAGAAATTCCTTTTTCTGTGAAAAAGACTAAGAGCATCTTCAACAGTGCCATGCAAGAGATGGAGGTTTACGTG
GAGAACATCCGCAGGAAGTTTGGGGTTTTTAATTACTCTCCATTTAGGACACCCTACACACCCAACAGCCAGTATCAAATGCTGCTCGAT
CCCACCAACCCCAGCGCCGGCACTGCCAAGATAGACAAGCAGGAGAAGGTCAAGCTCAACTTTGACATGACGGCATCCCCCAAGATCCTG
ATGAGCAAGCCTGTGCTGAGTGGGGGCACAGGCCGCCGGATTTCCTTGTCGGATATGCCGCGCTCCCCCATGAGCACAAACTCTTCTGTG
CACACGGGCTCCGACGTGGAGCAGGATGCTGAGAAGAAGGCCACGTCGAGCCACTTCAGTGCGAGCGAGGAGTCCATGGACTTCCTGGAT
AAGAGCACAGCTTCACCAGCCTCCACCAAGACGGGACAAGCAGGGAGTTTATCCGGCAGCCCAAAGCCCTTCTCTCCTCAACTGTCAGCT
CCTATCACGACGAAAACGGACAAAACCTCCACCACCGGCAGCATCCTGAATCTTAACCTGGATCGAAGCAAAGCTGAGATGGATTTGAAG
GAGCTGAGCGAGTCGGTCCAGCAACAGTCCACCCCTGTTCCTCTCATCTCTCCCAAGCGCCAGATTCGTAGCAGGTTCCAGCTGAATCTT
GACAAGACCATAGAGAGTTGCAAAGCACAATTAGGCATAAATGAAATCTCGGAAGATGTCTATACGGCCGTAGAGCACAGCGATTCGGAG
GATTCTGAGAAGTCAGATAGTAGCGATAGTGAGTATATCAGTGATGATGAGCAGAAGTCTAAGAACGAGCCAGAAGACACAGAGGACAAA
GAAGGTTGTCAGATGGACAAAGAGCCATCTGCTGTTAAAAAAAAGCCCAAGCCTACAAACCCAGTGGAGATTAAAGAGGAGCTGAAAAGC
ACGTCACCAGCCAGCGAGAAGGCAGACCCTGGAGCAGTCAAGGACAAGGCCAGCCCTGAGCCTGAGAAGGACTTTTCCGAAAAGGCAAAA
CCTTCACCTCACCCCATAAAGGATAAACTGAAGGGAAAAGATGAGACGGATTCCCCAACAGTCCATTTGGGCCTGGACTCTGATTCAGAG
AGCGAACTTGTCATAGATTTAGGAGAAGACCATTCTGGGCGGGAGGGTCGAAAAAATAAGAAGGAACCCAAAGAACCATCTCCCAAACAG
GATGTTGTAGGTAAAACTCCACCATCCACGACGGTGGGCAGCCATTCTCCCCCGGAAACACCGGTGCTCACCCGCTCTTCCGCCCAAACT
TCCGCGGCTGGCGCCACAGCCACCACCAGCACGTCCTCCACGGTCACCGTCACGGCCCCGGCCCCCGCCGCCACAGGAAGCCCAGTGAAA
AAGCAGAGGCCGCTTTTACCGAAGGAGACTGCCCCGGCCGTGCAGCGGGTCGTGTGGAACTCATCAAGTAAGTTTCAAACGTCCTCCCAA
AAGTGGCACATGCAGAAGATGCAGCGTCAGCAGCAGCAGCAGCAGCAGCAAAACCAGCAGCAGCAGCCTCAGTCTTCCCAGGGGACGAGA
TATCAGACCAGACAGGCTGTGAAAGCTGTCCAGCAGAAGGAGATCACACAGAGCCCATCCACGTCCACCATCACCCTGGTGACCAGCACA
CAGTCATCGCCCCTGGTCACCAGCTCGGGGTCCATGAGCACCCTTGTGTCCTCAGTCAACGCTGACCTGCCCATCGCCACTGCCTCAGCT
GATGTCGCCGCTGATATTGCCAAGTACACTAGCAAAATGATGGATGCAATAAAAGGAACAATGACAGAAATATACAACGATCTTTCTAAA
AACACTACTGGAAGCACAATAGCTGAGATTCGCAGGCTGAGGATCGAGATAGAGAAGCTCCAGTGGCTGCACCAGCAAGAGCTCTCCGAA
ATGAAACACAACTTAGAGCTGACCATGGCGGAGATGCGGCAGAGCCTGGAGCAGGAGCGGGACCGGCTCATCGCCGAGGTGAAGAAGCAG
CTGGAGTTGGAGAAGCAGCAGGCGGTGGATGAGACCAAGAAGAAGCAGTGGTGCGCCAACTGCAAGAAGGAGGCCATCTTTTACTGCTGT
TGGAACACTAGCTACTGTGACTACCCCTGCCAGCAAGCCCACTGGCCTGAGCACATGAAGTCCTGCACCCAGTCAGCTACTGCTCCTCAG
CAGGAAGCGGATGCTGAGGTGAACACAGAAACACTAAATAAGTCCTCCCAGGGGAGCTCCTCGAGCACACAATCAGCACCTTCAGAAACG
GCCAGCGCCTCCAAAGAGAAGGAGACGTCAGCTGAGAAAAGCAAGGAGAGTGGCTCGACCCTTGACCTTTCTGGCTCCAGAGAGACGCCC
TCCTCCATTCTCTTAGGCTCCAACCAAGGCTCTGACCATTCCCGGAGTAATAAATCCAGTTGGAGCAGCAGTGATGAGAAGAGGGGATCG


* Fusion transcript sequences (Full-length transcript).
>In-frame_SYCP2_ENST00000357552_chr20_58467045_-_ZMYND8_ENST00000311275_chr20_45927691_-_7524nt
TGCGGCGGTCCCTGAGGCGCAGAGTTGCGACGCTCGGCGGCATAGGGGGCGGCTCCACCGACACTACGCGGACGCCTCCTGCCGCAGATA
CACAATCATCATCTTACTAGTTCTCTGTGTTGCTCGCTAACCAGTCCCCCAGTTCAGTAGACTGGAGCCCAGAGCCTGCTTACTTGTCAG
GTGTTTATTTTGTCTTGCTTTTTTTTTTTTTTTAAATGAAGTCAAAATGCCAATAAGACCAGATCTCCAGCAGTTGGAAAAATGCATTGA
TGATGCTTTAAGAAAAAATGATTTCAAACCTTTGAAAACACTTTTGCAAATTGATATTTGTGAAGATGTGAAGATTAAATGCAGCAAACA
GTTTTTCCACAAGGTGGACAACCTTATATGCAGGGAACTTAATAAAGAGGATATCCACAATGTTTCAGCCATTTTGGTTTCTGTTGGAAG
ATGTGGCAAAAATATCAGTGTATTGGGGCAAGCTGGACTTCTAACGATGATAAAACAAGGACTAATACAAAAGATGGTTGCCTGGTTTGA
AAAATCCAAGGACATTATTCAGAGTCAAGGAAATTCAAAAGATGAAGCTGTTCTAAATATGATAGAAGACTTAGTTGATCTTCTGCTGGT
CATACATGATGTCAGTGATGAAGGTAAAAAACAAGTAGTGGAAAGTTTCGTACCTCGCATTTGTTCCCTGGTTATTGACTCAAGAGTGAA
TATTTGTATTCAGCAAGAGATTATAAAAAAAATGAATGCTATGCTTGACAAAATGCCTCAAGATGCCCGGAAAATACTCTCTAACCAAGA
AATGTTAATTCTCATGAGTAGTATGGGAGAAAGGATTTTAGATGCTGGAGATTATGACTTACAGGTAGGCATTGTAGAAGCTTTGTGTAG
AATGACCACAGAAAAACAAAGACAAGAACTGGCACATCAGTGGTTTTCAATGGATTTTATTGCTAAGGCATTTAAAAGAATTAAGGACTC
TGAATTTGAAACAGATTGCAGGATATTTCTCAACCTTGTAAATGGCATGCTTGGAGACAAAAGAAGGGTCTTTACATTTCCTTGTTTATC
AGCATTTCTTGATAAATATGAGCTGCAAATACCATCAGATGAAAAACTTGAGGAATTTTGGATTGATTTTAATCTTGGGAGTCAGACTCT
CTCATTCTACATTGCTGGAGATAATGATGATCATCAATGGGAAGCAGTTACTGTGCCAGAGGAAAAAGTACAAATATACAGCATTGAAGT
GAGAGAATCAAAGAAGCTACTGACAATAATTCTGAAAAATACAGTAAAAATTAGCAAAAGAGAAGGGAAAGAATTGCTTTTGTATTTTGA
CGCATCACTAGAAATCACTAATGTAACTCAAAAAATTTTTGGTGCAACTAAACATAGGGAATCTATCAGAAAACAAGGTATTTCAGTTGC
CAAAACGTCGCTGCATATACTTTTTGACGCAAGTGGATCACAGATTCTAGTGCCAGAAAGTCAAATCTCACCAGTCGGAGAAGAGCTCGT
TAGTTTAAAGGAAAAATCAAAGTCCCCAAAGGAATTTGCTAAACCTTCAAAATATATCAAAAACAGTGACAAAGGGAATAGAAATAATAG
TCAGCTTGAGAAAACTACTCCTAGCAAAAGAAAAATGTCTGAAGCATCAATGATTGTTTCTGGTGCAGATAGATACACTATGAGAAGTCC
AGTGCTTTTCAGCAACACATCAATACCACCACGAAGAAGAAGAATTAAACCACCACTGCAAATGACGAGCTCTGCAGAGAAACCTAGTGT
TTCTCAAACATCAGAAAATAGAGTGGATAATGCTGCATCACTGAAATCTAGATCATCAGAAGGAAGACATAGAAGAGATAATATAGACAA
ACATATCAAAACTGCTAAGTGTGTAGAAAACACAGAAAATAAGAATGTTGAATTCCCAAACCAAAATTTTAGTGAACTCCAGGATGTTAT
ACCAGATTCACAGGCAGCGGAAAAAAGAGATCATACTATATTACCTGGTGTTTTAGACAACATCTGTGGAAATAAAATACACAGCAAATG
GGCATGTTGGACACCTGTAACAAACATTGAACTATGTAATAACCAAAGAGCAAGTACTTCGTCAGGAGACACATTGAATCAAGATATTGT
TATAAATAAAAAACTTACTAAACAAAAATCATCCTCTTCAATATCTGATCATAATTCTGAAGGAACAGGAAAAGTGAAATATAAGAAAGA
ACAAACCGACCATATCAAAATAGATAAAGCAGAAGTAGAAGTTTGCAAGAAACACAATCAGCAACAAAATCATCCTAAATATTCAGGGCA
GAAAAATACTGAAAATGCCAAGCAGAGTGATTGGCCTGTTGAATCTGAAACTACTTTTAAATCGGTTCTCCTAAATAAGACAATTGAAGA
ATCGCTGATATATAGGAAGAAATACATATTGTCAAAAGATGTGAATACTGCTACTTGCGATAAAAATCCATCTGCTAGCAAAAATGTGCA
AAGTCATAGAAAAGCAGAGAAAGAATTGACTTCTGAGCTTAATTCCTGGGATTCGAAACAAAAAAAAATGTCAGAACTAAGACATGGTCC
GTTTTACTATATGAAGCAGCCACTCACCACAGACCCTGTTGATGTTGTACCGCAGGATGGACGGAATGATTTCTACTGCTGGGTTTGTCA
CCGGGAAGGCCAAGTCCTTTGCTGTGAGCTCTGTCCCCGGGTTTATCACGCTAAGTGTCTGAGACTGACATCGGAACCAGAGGGGGACTG
GTTTTGTCCTGAATGTGAGAAAATTACAGTAGCAGAATGCATCGAGACCCAGAGTAAAGCCATGACAATGCTCACCATTGAACAGTTATC
CTACCTGCTCAAGTTTGCCATTCAGAAAATGAAACAGCCAGGGACAGATGCATTCCAGAAGCCCGTTCCATTGGAACAGCACCCTGACTA
TGCGGAATACATCTTCCATCCAATGGACCTTTGTACATTGGAAAAGAATGCGAAAAAGAAAATGTATGGCTGCACAGAAGCCTTCCTGGC
TGATGCAAAGTGGATTTTGCACAACTGCATCATTTATAATGGGGGAAATCACAAATTGACGCAAATAGCGAAAGTAGTCATCAAAATCTG
TGAACATGAGATGAATGAAATCGAAGTATGTCCAGAATGTTATCTAGCTGCTTGCCAAAAACGAGATAACTGGTTTTGTGAGCCTTGTAG
CAATCCACATCCTTTGGTCTGGGCCAAACTGAAGGGGTTTCCATTCTGGCCTGCAAAAGCTCTAAGGGATAAAGACGGGCAGGTCGATGC
CCGATTCTTTGGACAACATGACAGGGCCTGGGTTCCAATAAATAATTGCTACCTCATGTCTAAAGAAATTCCTTTTTCTGTGAAAAAGAC
TAAGAGCATCTTCAACAGTGCCATGCAAGAGATGGAGGTTTACGTGGAGAACATCCGCAGGAAGTTTGGGGTTTTTAATTACTCTCCATT
TAGGACACCCTACACACCCAACAGCCAGTATCAAATGCTGCTCGATCCCACCAACCCCAGCGCCGGCACTGCCAAGATAGACAAGCAGGA
GAAGGTCAAGCTCAACTTTGACATGACGGCATCCCCCAAGATCCTGATGAGCAAGCCTGTGCTGAGTGGGGGCACAGGCCGCCGGATTTC
CTTGTCGGATATGCCGCGCTCCCCCATGAGCACAAACTCTTCTGTGCACACGGGCTCCGACGTGGAGCAGGATGCTGAGAAGAAGGCCAC
GTCGAGCCACTTCAGTGCGAGCGAGGAGTCCATGGACTTCCTGGATAAGAGCACAGCTTCACCAGCCTCCACCAAGACGGGACAAGCAGG
GAGTTTATCCGGCAGCCCAAAGCCCTTCTCTCCTCAACTGTCAGCTCCTATCACGACGAAAACGGACAAAACCTCCACCACCGGCAGCAT
CCTGAATCTTAACCTGGATCGAAGCAAAGCTGAGATGGATTTGAAGGAGCTGAGCGAGTCGGTCCAGCAACAGTCCACCCCTGTTCCTCT
CATCTCTCCCAAGCGCCAGATTCGTAGCAGGTTCCAGCTGAATCTTGACAAGACCATAGAGAGTTGCAAAGCACAATTAGGCATAAATGA
AATCTCGGAAGATGTCTATACGGCCGTAGAGCACAGCGATTCGGAGGATTCTGAGAAGTCAGATAGTAGCGATAGTGAGTATATCAGTGA
TGATGAGCAGAAGTCTAAGAACGAGCCAGAAGACACAGAGGACAAAGAAGGTTGTCAGATGGACAAAGAGCCATCTGCTGTTAAAAAAAA
GCCCAAGCCTACAAACCCAGTGGAGATTAAAGAGGAGCTGAAAAGCACGTCACCAGCCAGCGAGAAGGCAGACCCTGGAGCAGTCAAGGA
CAAGGCCAGCCCTGAGCCTGAGAAGGACTTTTCCGAAAAGGCAAAACCTTCACCTCACCCCATAAAGGATAAACTGAAGGGAAAAGATGA
GACGGATTCCCCAACAGTCCATTTGGGCCTGGACTCTGATTCAGAGAGCGAACTTGTCATAGATTTAGGAGAAGACCATTCTGGGCGGGA
GGGTCGAAAAAATAAGAAGGAACCCAAAGAACCATCTCCCAAACAGGATGTTGTAGGTAAAACTCCACCATCCACGACGGTGGGCAGCCA
TTCTCCCCCGGAAACACCGGTGCTCACCCGCTCTTCCGCCCAAACTTCCGCGGCTGGCGCCACAGCCACCACCAGCACGTCCTCCACGGT
CACCGTCACGGCCCCGGCCCCCGCCGCCACAGGAAGCCCAGTGAAAAAGCAGAGGCCGCTTTTACCGAAGGAGACTGCCCCGGCCGTGCA
GCGGGTCGTGTGGAACTCATCAAGTAAGTTTCAAACGTCCTCCCAAAAGTGGCACATGCAGAAGATGCAGCGTCAGCAGCAGCAGCAGCA
GCAGCAAAACCAGCAGCAGCAGCCTCAGTCTTCCCAGGGGACGAGATATCAGACCAGACAGGCTGTGAAAGCTGTCCAGCAGAAGGAGAT
CACACAGAGCCCATCCACGTCCACCATCACCCTGGTGACCAGCACACAGTCATCGCCCCTGGTCACCAGCTCGGGGTCCATGAGCACCCT
TGTGTCCTCAGTCAACGCTGACCTGCCCATCGCCACTGCCTCAGCTGATGTCGCCGCTGATATTGCCAAGTACACTAGCAAAATGATGGA
TGCAATAAAAGGAACAATGACAGAAATATACAACGATCTTTCTAAAAACACTACTGGAAGCACAATAGCTGAGATTCGCAGGCTGAGGAT
CGAGATAGAGAAGCTCCAGTGGCTGCACCAGCAAGAGCTCTCCGAAATGAAACACAACTTAGAGCTGACCATGGCGGAGATGCGGCAGAG
CCTGGAGCAGGAGCGGGACCGGCTCATCGCCGAGGTGAAGAAGCAGCTGGAGTTGGAGAAGCAGCAGGCGGTGGATGAGACCAAGAAGAA
GCAGTGGTGCGCCAACTGCAAGAAGGAGGCCATCTTTTACTGCTGTTGGAACACTAGCTACTGTGACTACCCCTGCCAGCAAGCCCACTG
GCCTGAGCACATGAAGTCCTGCACCCAGTCAGCTACTGCTCCTCAGCAGGAAGCGGATGCTGAGGTGAACACAGAAACACTAAATAAGTC
CTCCCAGGGGAGCTCCTCGAGCACACAATCAGCACCTTCAGAAACGGCCAGCGCCTCCAAAGAGAAGGAGACGTCAGCTGAGAAAAGCAA
GGAGAGTGGCTCGACCCTTGACCTTTCTGGCTCCAGAGAGACGCCCTCCTCCATTCTCTTAGGCTCCAACCAAGGCTCTGACCATTCCCG
GAGTAATAAATCCAGTTGGAGCAGCAGTGATGAGAAGAGGGGATCGACACGTTCCGATCACAACACCAGTACCAGCACGAAGAGCCTCCT
CCCGAAAGAGTCTCGGCTGGACACCTTCTGGGACTAGCAGTGAATCGGGACACAAACCACCCACCCCATTGGGAGAAAAACCCAGACGCC
AGGAAAAGAAGAAACAACAAAGGCAGGAGAACAGCCACTTTCAGACTTGAAAATGACAAAACCCTCAGTTGAGCCTGAGCCCCCGGCGCG
GGGGCTGCTACACTACAGGACACCCAGCATCGGCTTTGACTGCAGACTGTTCACCCACACGAGCCCTGTGCTTTTGGTGTAAATAATGTA
CAATTTGTGGATGTCATTGAATCTAGAGGACTTTCCCCTTTTTATATTTGTATTAACTTTAACTTATTAAAAAAAAAAAAAGAAAAAGAA
AAACGATTTAAAAAAAAAAAAAAAAGCAACCAACCCCAACAACAAAAAAGAATGTTTTGGTATTGGAGAAGGGATGGTCAGTTAGCCTGT
CTGTCACACGACGGAATGGATACTGGGCCCGGGGACCACTTTCATACTCACGTCCTCATCCTTGGATACCCAGGGGAGGGCGAACCGTTT
TCGCTCGTGTGTCTGTACGCAGCATGTTGGGATCGGGAGTTTCGGCACAGACTATCCCATCAAGCCGTTGGCTCCTTTCAGCTACTACGT
TACCACGTTCCTAAAACGCAAGCTCTCCGGACCAGACGGACACAGGGAGAAGCTAGTTTCTTTCATGTGATTGAAATGATGACTCTACTC
CTAAAAGGGAAAAAACAATATCCTTGTTTACAGAAGAGAAACAAACAAGCCCCACTCAGCTCAGTCACAGGAGAGAACACAGAAAGTCTT
AGGATCATGAACTCTGAAAAAAAGAGAAACCTTATCTTTGCTTTGTGGTTCCTTTAAACACACTCACACACACTTGGTCAGAGATGCTGT
GCTTCTTGGAAGCAAGGACTCAAAGGCAAGGTGCACGCAGAGGACGTTTGAGTCTGGGATGAAGCATGTACGTATTATTTATATGATGGA
ATTTCACGTTTTTATGTAAGCATGAAACACAGGCAGTATGAGAGAAAGCAAGGCCCGTCATGCTGTCCGTACACTACGTATGCTGTAGAG
CCATTTTGTATGTTGTGTAAAACAAAAAGCATTGATGAAAAAGCAAAAGGTGATGTATGTATATGAGAAAATTAATTGTACGATATCATT
CCAGTACGTTTTGTTGTACATTTTAGTCTTGTTTACTTTCTCTTCATTGTTAAGAGGATGCGAACTGTACAGTTTCCAGCTAGTTACCCA
TATTAGAGAAGAAATAAGAGAGTATTAGAAGAAAACAGGAGAGAAAGAACATTTGTGAATTGCAGTTGTCAAAAAAAAAAAATAGCCTAG
CTGGCCTTATTTGTGAAGCATAATTGCTTTTAGCATATGGAAGTATTTTTTCACATTTTCTTTGTATAAAATTTGTATTAAACTTAAATA
TCTTTTTGATGGTGGTGTTTCTTTGTGACTGAGCCAGTAGACTCACACTATATGCTTTTTTGGGTTTGCCCGTTCCTTCCCCCACCCCCC


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FusionGenePPI for SYCP2_ZMYND8


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
SYCP2SRPK2ZMYND8FHOD1, E2F6, SMARCA4, INTS1, INTS3, INTS5, INTS6, BCL6, CSNK1E, ATN1, RERE, USP7, SUPT4H1, ZFYVE9, SOX2, HDAC1, PBXIP1, ZBTB7A, HECW2, KCTD17, CSNK2A2, CHD4, HDAC2, KRAS, PSMD5, RBBP7, TSPYL1, MBD2, MTA1, MTA2, ZNF592, CHERP, MGA, CDK2AP1, RBM8A, ZNF687, VWA9, KDM5C, RPS27L, ZCCHC17, ESF1, MBD3, GATAD2A, ZNF532, DDX24, GATAD2B, MTA3, TSPYL2, FOXJ2, P4HA3, LLGL2, ZNF408


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneZMYND8chr20:58467045chr20:45927691ENST00000262975-32475_406581169histone H3K14ac
TgeneZMYND8chr20:58467045chr20:45927691ENST00000311275-22275_406581187histone H3K14ac
TgeneZMYND8chr20:58467045chr20:45927691ENST00000352431-22275_406781161histone H3K14ac
TgeneZMYND8chr20:58467045chr20:45927691ENST00000355972-32475_406581215histone H3K14ac
TgeneZMYND8chr20:58467045chr20:45927691ENST00000360911-02275_406-121136histone H3K14ac
TgeneZMYND8chr20:58467045chr20:45927691ENST00000461685-22375_406781189histone H3K14ac
TgeneZMYND8chr20:58467045chr20:45927691ENST00000471951-22375_406781235histone H3K14ac
TgeneZMYND8chr20:58467045chr20:45927691ENST00000262975-32475_268581169histone H3K4me0
TgeneZMYND8chr20:58467045chr20:45927691ENST00000311275-22275_268581187histone H3K4me0
TgeneZMYND8chr20:58467045chr20:45927691ENST00000352431-22275_268781161histone H3K4me0
TgeneZMYND8chr20:58467045chr20:45927691ENST00000355972-32475_268581215histone H3K4me0
TgeneZMYND8chr20:58467045chr20:45927691ENST00000360911-02275_268-121136histone H3K4me0
TgeneZMYND8chr20:58467045chr20:45927691ENST00000461685-22375_268781189histone H3K4me0
TgeneZMYND8chr20:58467045chr20:45927691ENST00000471951-22375_268781235histone H3K4me0
TgeneZMYND8chr20:58467045chr20:45927691ENST00000262975-3241147_1186581169PRKCB1
TgeneZMYND8chr20:58467045chr20:45927691ENST00000311275-2221147_1186581187PRKCB1
TgeneZMYND8chr20:58467045chr20:45927691ENST00000352431-2221147_1186781161PRKCB1
TgeneZMYND8chr20:58467045chr20:45927691ENST00000355972-3241147_1186581215PRKCB1
TgeneZMYND8chr20:58467045chr20:45927691ENST00000360911-0221147_1186-121136PRKCB1
TgeneZMYND8chr20:58467045chr20:45927691ENST00000461685-2231147_1186781189PRKCB1
TgeneZMYND8chr20:58467045chr20:45927691ENST00000471951-2231147_1186781235PRKCB1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for SYCP2_ZMYND8


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SYCP2_ZMYND8


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource