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Fusion gene ID: 36691 |
FusionGeneSummary for STXBP6_ZNF410 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: STXBP6_ZNF410 | Fusion gene ID: 36691 | Hgene | Tgene | Gene symbol | STXBP6 | ZNF410 | Gene ID | 29091 | 57862 |
| Gene name | syntaxin binding protein 6 | zinc finger protein 410 | |
| Synonyms | HSPC156|amisyn | APA-1|APA1 | |
| Cytomap | 14q12 | 14q24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | syntaxin-binding protein 6 | zinc finger protein 410another partner for ARF 1clones 23667 and 23775 zinc finger proteinzinc finger protein APA-1 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q8NFX7 | Q86VK4 | |
| Ensembl transtripts involved in fusion gene | ENST00000548724, ENST00000396700, ENST00000323944, ENST00000419632, ENST00000546511, ENST00000550887, ENST00000358326, ENST00000548369, | ENST00000540593, ENST00000324593, ENST00000412490, ENST00000442160, ENST00000555044, ENST00000334521, ENST00000556797, | |
| Fusion gene scores | * DoF score | 4 X 2 X 4=32 | 1 X 1 X 1=1 |
| # samples | 4 | 1 | |
| ** MAII score | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: STXBP6 [Title/Abstract] AND ZNF410 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | STXBP6 | GO:0035542 | regulation of SNARE complex assembly | 12145319 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-A6YT-01A | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000548724 | ENST00000540593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| Frame-shift | ENST00000548724 | ENST00000324593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000548724 | ENST00000412490 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000548724 | ENST00000442160 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000548724 | ENST00000555044 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000548724 | ENST00000334521 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-intron | ENST00000548724 | ENST00000556797 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| Frame-shift | ENST00000396700 | ENST00000540593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| Frame-shift | ENST00000396700 | ENST00000324593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000396700 | ENST00000412490 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000396700 | ENST00000442160 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000396700 | ENST00000555044 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000396700 | ENST00000334521 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-intron | ENST00000396700 | ENST00000556797 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| In-frame | ENST00000323944 | ENST00000540593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| In-frame | ENST00000323944 | ENST00000324593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000323944 | ENST00000412490 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000323944 | ENST00000442160 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000323944 | ENST00000555044 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000323944 | ENST00000334521 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-intron | ENST00000323944 | ENST00000556797 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| Frame-shift | ENST00000419632 | ENST00000540593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| Frame-shift | ENST00000419632 | ENST00000324593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000419632 | ENST00000412490 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000419632 | ENST00000442160 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000419632 | ENST00000555044 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000419632 | ENST00000334521 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-intron | ENST00000419632 | ENST00000556797 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| In-frame | ENST00000546511 | ENST00000540593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| In-frame | ENST00000546511 | ENST00000324593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000546511 | ENST00000412490 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000546511 | ENST00000442160 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000546511 | ENST00000555044 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000546511 | ENST00000334521 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-intron | ENST00000546511 | ENST00000556797 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| In-frame | ENST00000550887 | ENST00000540593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| In-frame | ENST00000550887 | ENST00000324593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000550887 | ENST00000412490 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000550887 | ENST00000442160 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000550887 | ENST00000555044 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000550887 | ENST00000334521 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-intron | ENST00000550887 | ENST00000556797 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| In-frame | ENST00000358326 | ENST00000540593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| In-frame | ENST00000358326 | ENST00000324593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000358326 | ENST00000412490 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000358326 | ENST00000442160 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000358326 | ENST00000555044 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-3UTR | ENST00000358326 | ENST00000334521 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| 5CDS-intron | ENST00000358326 | ENST00000556797 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| intron-3CDS | ENST00000548369 | ENST00000540593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| intron-3CDS | ENST00000548369 | ENST00000324593 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| intron-3UTR | ENST00000548369 | ENST00000412490 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| intron-3UTR | ENST00000548369 | ENST00000442160 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| intron-3UTR | ENST00000548369 | ENST00000555044 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| intron-3UTR | ENST00000548369 | ENST00000334521 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
| intron-intron | ENST00000548369 | ENST00000556797 | STXBP6 | chr14 | 25443871 | - | ZNF410 | chr14 | 74370663 | + |
Top |
FusionProtFeatures for STXBP6_ZNF410 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| STXBP6 | ZNF410 |
| Forms non-fusogenic complexes with SNAP25 and STX1A andmay thereby modulate the formation of functional SNARE complexesand exocytosis. | Transcription factor that activates transcription ofmatrix-remodeling genes such as MMP1 during fibroblast senescence.{ECO:0000269|PubMed:12370286}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for STXBP6_ZNF410 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_STXBP6_ENST00000323944_chr14_25443871_-_ZNF410_ENST00000540593_chr14_74370663_+_337aa MSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVW PAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAE YSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQPSLGGESLNL >In-frame_STXBP6_ENST00000323944_chr14_25443871_-_ZNF410_ENST00000324593_chr14_74370663_+_290aa MSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVW PAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAE YSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTEVLAEGSPRSLSSVPDVTHHLVTMQSGRQSYEVSVL >In-frame_STXBP6_ENST00000546511_chr14_25443871_-_ZNF410_ENST00000540593_chr14_74370663_+_337aa MSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVW PAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAE YSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQPSLGGESLNL >In-frame_STXBP6_ENST00000546511_chr14_25443871_-_ZNF410_ENST00000324593_chr14_74370663_+_290aa MSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVW PAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAE YSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTEVLAEGSPRSLSSVPDVTHHLVTMQSGRQSYEVSVL >In-frame_STXBP6_ENST00000550887_chr14_25443871_-_ZNF410_ENST00000540593_chr14_74370663_+_337aa MSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVW PAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAE YSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQPSLGGESLNL >In-frame_STXBP6_ENST00000550887_chr14_25443871_-_ZNF410_ENST00000324593_chr14_74370663_+_290aa MSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVW PAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAE YSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTEVLAEGSPRSLSSVPDVTHHLVTMQSGRQSYEVSVL >In-frame_STXBP6_ENST00000358326_chr14_25443871_-_ZNF410_ENST00000540593_chr14_74370663_+_337aa MSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVW PAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAE YSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTAEPLMGSSLLEEASVPSKNLVSMNSQPSLGGESLNL >In-frame_STXBP6_ENST00000358326_chr14_25443871_-_ZNF410_ENST00000324593_chr14_74370663_+_290aa MSAKSAISKEIFAPLDERMLGAVQVKRRTKKKIPFLATGGQGEYLTYICLSGENVHLGSGDGQSKDSGPLPQVEKKLKCTVEGCDRTFVW PAHFKYHLKTHRNDRSFICPAEGCGKSFYVLQRLKVHMRTHNGEKPFMCHESGCGKQFTTAGNLKNHRRIHTGEKPFLCEAQGCGRSFAE YSSLRKHLVVHSGEKPHQCQVCGKTFSQSGSRNVHMRKHHLQLGAAGSQEQEQTEVLAEGSPRSLSSVPDVTHHLVTMQSGRQSYEVSVL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_STXBP6_ENST00000323944_chr14_25443871_-_ZNF410_ENST00000540593_chr14_74370663_+_1011nt ATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAG AAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGT GATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGG CCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTG CTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACA GCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAG TATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGA AGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGGGC AGTAGTTTGCTTGAAGAGGCTTCAGTACCCAGTAAAAACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACCTA CCAAATACCAATTCTATCCTGGGAGTTGATGATGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACAT CACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGAT >In-frame_STXBP6_ENST00000323944_chr14_25443871_-_ZNF410_ENST00000324593_chr14_74370663_+_870nt ATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAG AAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGT GATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGG CCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTG CTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACA GCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAG TATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGA AGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAGGA TCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTA >In-frame_STXBP6_ENST00000546511_chr14_25443871_-_ZNF410_ENST00000540593_chr14_74370663_+_1011nt ATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAG AAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGT GATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGG CCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTG CTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACA GCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAG TATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGA AGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGGGC AGTAGTTTGCTTGAAGAGGCTTCAGTACCCAGTAAAAACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACCTA CCAAATACCAATTCTATCCTGGGAGTTGATGATGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACAT CACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGAT >In-frame_STXBP6_ENST00000546511_chr14_25443871_-_ZNF410_ENST00000324593_chr14_74370663_+_870nt ATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAG AAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGT GATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGG CCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTG CTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACA GCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAG TATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGA AGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAGGA TCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTA >In-frame_STXBP6_ENST00000550887_chr14_25443871_-_ZNF410_ENST00000540593_chr14_74370663_+_1011nt ATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAG AAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGT GATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGG CCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTG CTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACA GCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAG TATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGA AGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGGGC AGTAGTTTGCTTGAAGAGGCTTCAGTACCCAGTAAAAACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACCTA CCAAATACCAATTCTATCCTGGGAGTTGATGATGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACAT CACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGAT >In-frame_STXBP6_ENST00000550887_chr14_25443871_-_ZNF410_ENST00000324593_chr14_74370663_+_870nt ATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAG AAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGT GATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGG CCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTG CTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACA GCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAG TATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGA AGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAGGA TCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTA >In-frame_STXBP6_ENST00000358326_chr14_25443871_-_ZNF410_ENST00000540593_chr14_74370663_+_1011nt ATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAG AAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGT GATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGG CCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTG CTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACA GCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAG TATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGA AGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGGGC AGTAGTTTGCTTGAAGAGGCTTCAGTACCCAGTAAAAACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACCTA CCAAATACCAATTCTATCCTGGGAGTTGATGATGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACAT CACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGAT >In-frame_STXBP6_ENST00000358326_chr14_25443871_-_ZNF410_ENST00000324593_chr14_74370663_+_870nt ATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAG AAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGT GATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGG CCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTG CTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACA GCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAG TATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGA AGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAGGA TCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_STXBP6_ENST00000323944_chr14_25443871_-_ZNF410_ENST00000540593_chr14_74370663_+_1519nt GAGGCCTGGGGCGGGTCGCGGGTCCCGGCCCCCAGCCCCCAGCCCCTAGCCGCTGCTCTTTGCCCCGGGCCAGGGCGCTCGGGCTCGCCC ACGGCGGCACTGAGCATGCTCAGAGGCGGCCGCGCGGGCAGGTTTGCTTCGCAGGCGCTCGCACTCGGCGGCGGGCGGGCGCGCGGCTGC AGCTGGAGCTCCAGCGCCCGGAGTTGGAGTTGCCGGGAGTTTCCCCCCAACCCCTCCCTTTTCGCGCGCGGCAGCAGGAGCCGGCGCGGG AGCCGCGAGCGGCGGCGAGCCAGCACCCGGGCCGGCTAAGCCTTGTCCGGAGCCCGGAGCCCCGCGCGGGGCAGCCCCCCGGGGAGGAGC CTCGTGCTCTGGGACGCGTGCCGCGCACTGGCACGGCAGGGGCGCGAGCCAGGCTGCACGATTCACTGCGTGCTGTCCTCACTTGTTCTA CAATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAA AGAAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTG GTGATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTAT GGCCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATG TGCTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTA CAGCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTG AGTATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTG GAAGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGG GCAGTAGTTTGCTTGAAGAGGCTTCAGTACCCAGTAAAAACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACC TACCAAATACCAATTCTATCCTGGGAGTTGATGATGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACAC ATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAG >In-frame_STXBP6_ENST00000323944_chr14_25443871_-_ZNF410_ENST00000324593_chr14_74370663_+_2059nt GAGGCCTGGGGCGGGTCGCGGGTCCCGGCCCCCAGCCCCCAGCCCCTAGCCGCTGCTCTTTGCCCCGGGCCAGGGCGCTCGGGCTCGCCC ACGGCGGCACTGAGCATGCTCAGAGGCGGCCGCGCGGGCAGGTTTGCTTCGCAGGCGCTCGCACTCGGCGGCGGGCGGGCGCGCGGCTGC AGCTGGAGCTCCAGCGCCCGGAGTTGGAGTTGCCGGGAGTTTCCCCCCAACCCCTCCCTTTTCGCGCGCGGCAGCAGGAGCCGGCGCGGG AGCCGCGAGCGGCGGCGAGCCAGCACCCGGGCCGGCTAAGCCTTGTCCGGAGCCCGGAGCCCCGCGCGGGGCAGCCCCCCGGGGAGGAGC CTCGTGCTCTGGGACGCGTGCCGCGCACTGGCACGGCAGGGGCGCGAGCCAGGCTGCACGATTCACTGCGTGCTGTCCTCACTTGTTCTA CAATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAA AGAAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTG GTGATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTAT GGCCAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATG TGCTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTA CAGCTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTG AGTATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTG GAAGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAG GATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCT TAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTCCTGGAAGAGCAA CTCTATCTGATCTCAAAATGCGTATACTGGGAACAGGATGCCTTAGCCCACAACAGAACCAGAATGAATCTTTGAAGGCACAAGACTCTG CTTTTGCCACTCTTCCTCTTTCCTGGTATAGAAGATGGATGTAGGAGAGCTTCTTTTCTAACTACCATCTGATCAGACAAGGAATGAAGC AATGACTGTGGGCTGGGAAACTGTACCTACCTCTCTTCCCACTGCAAATTTCTGGGATAGACCAAAAGTGAATTTGATTATGTGTTGGCT GAAGTTCTTCATTCTGACTGTTGAGGGGAGGTTTTCCTTTGAAGAGTTTTCATCCCAGACTCAGCTGTCTTTTCACATGGATGAAATAAT TCCTGCTACCAACAACAGAGCTTCACCAGGAAGTTGAGTTTTCAAGATGCCTTGTTGCTTTGAAGAAGGGAGTGATGTCAATTCTCTTGT TACATTCTCCCTTTAGCAACCTGAGTAAGAGACTCTCTGCCACTGGGCTGCAAAAAAATAAATTACTTGAATCTCCCCTTGGCCCAGGCT GAGGTACTATCTTGTCCTATACACTTCTACTTGGTCACTTTGCTTTCTTCGTTAATGGAACATACAGTAGCATGTTAAGAGGGATTTCAT >In-frame_STXBP6_ENST00000546511_chr14_25443871_-_ZNF410_ENST00000540593_chr14_74370663_+_1140nt ATTACGCTTCCCTAGGGACTGGGTGGGAGAGAATAGGATCGATTCACTGCGTGCTGTCCTCACTTGTTCTACAATGAGTGCCAAATCTGC TATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGAAAAAGATTCCTTTCTT GGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTGATGGGCAGTCAAAAGA TTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGCCAGCTCACTTTAAATA CCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGCTGCAGAGGCTGAAGGT GCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAGCTGGAAACCTGAAGAA CCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGTATTCTAGCCTCCGAAA ACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAAGCAGGAATGTGCATAT GAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGGGCAGTAGTTTGCTTGAAGA GGCTTCAGTACCCAGTAAAAACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACCTACCAAATACCAATTCTAT CCTGGGAGTTGATGATGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCA GTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGAC >In-frame_STXBP6_ENST00000546511_chr14_25443871_-_ZNF410_ENST00000324593_chr14_74370663_+_1680nt ATTACGCTTCCCTAGGGACTGGGTGGGAGAGAATAGGATCGATTCACTGCGTGCTGTCCTCACTTGTTCTACAATGAGTGCCAAATCTGC TATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGAAAAAGATTCCTTTCTT GGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTGATGGGCAGTCAAAAGA TTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGCCAGCTCACTTTAAATA CCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGCTGCAGAGGCTGAAGGT GCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAGCTGGAAACCTGAAGAA CCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGTATTCTAGCCTCCGAAA ACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAAGCAGGAATGTGCATAT GAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTC TTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACA AGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTCCTGGAAGAGCAACTCTATCTGATCTCAAAAT GCGTATACTGGGAACAGGATGCCTTAGCCCACAACAGAACCAGAATGAATCTTTGAAGGCACAAGACTCTGCTTTTGCCACTCTTCCTCT TTCCTGGTATAGAAGATGGATGTAGGAGAGCTTCTTTTCTAACTACCATCTGATCAGACAAGGAATGAAGCAATGACTGTGGGCTGGGAA ACTGTACCTACCTCTCTTCCCACTGCAAATTTCTGGGATAGACCAAAAGTGAATTTGATTATGTGTTGGCTGAAGTTCTTCATTCTGACT GTTGAGGGGAGGTTTTCCTTTGAAGAGTTTTCATCCCAGACTCAGCTGTCTTTTCACATGGATGAAATAATTCCTGCTACCAACAACAGA GCTTCACCAGGAAGTTGAGTTTTCAAGATGCCTTGTTGCTTTGAAGAAGGGAGTGATGTCAATTCTCTTGTTACATTCTCCCTTTAGCAA CCTGAGTAAGAGACTCTCTGCCACTGGGCTGCAAAAAAATAAATTACTTGAATCTCCCCTTGGCCCAGGCTGAGGTACTATCTTGTCCTA TACACTTCTACTTGGTCACTTTGCTTTCTTCGTTAATGGAACATACAGTAGCATGTTAAGAGGGATTTCATGTTTTTGTTTTTTTAAAGT >In-frame_STXBP6_ENST00000550887_chr14_25443871_-_ZNF410_ENST00000540593_chr14_74370663_+_1336nt TTTCCTGTTTAGAAAGTTCTGCTCCTTCATAAGGACCTTGAAGTACTAGGAGGAAAGGTGCTTTGTGTGTGGAGTTTTCCATGAAGTGCA GTCCCAACTAAAAGGCTGCGTTAAAGGCTAGAGTAGTGCAGTGGCGTGATCTCAGCTCACTCCAGCCTCTGCCTCCCGGGCTCAAGTGAC CCACCTGCCTCAGCCTCCCAAGTAGCTGGGACAACAGATGTGAGCCACCACACCCAGATTCACTGCGTGCTGTCCTCACTTGTTCTACAA TGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGA AAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTG ATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGC CAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGC TGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAG CTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGT ATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAA GCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGGGCA GTAGTTTGCTTGAAGAGGCTTCAGTACCCAGTAAAAACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACCTAC CAAATACCAATTCTATCCTGGGAGTTGATGATGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATC ACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATT >In-frame_STXBP6_ENST00000550887_chr14_25443871_-_ZNF410_ENST00000324593_chr14_74370663_+_1876nt TTTCCTGTTTAGAAAGTTCTGCTCCTTCATAAGGACCTTGAAGTACTAGGAGGAAAGGTGCTTTGTGTGTGGAGTTTTCCATGAAGTGCA GTCCCAACTAAAAGGCTGCGTTAAAGGCTAGAGTAGTGCAGTGGCGTGATCTCAGCTCACTCCAGCCTCTGCCTCCCGGGCTCAAGTGAC CCACCTGCCTCAGCCTCCCAAGTAGCTGGGACAACAGATGTGAGCCACCACACCCAGATTCACTGCGTGCTGTCCTCACTTGTTCTACAA TGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTGCACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGA AAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCGAATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTG ATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAGTGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGC CAGCTCACTTTAAATACCACCTCAAGACTCATCGAAATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGC TGCAGAGGCTGAAGGTGCACATGAGGACCCACAATGGAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAG CTGGAAACCTGAAGAACCACCGGCGCATCCACACAGGAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGT ATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAGGAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAA GCAGGAATGTGCATATGAGAAAGCATCACCTGCAGCTGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAGGAT CCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAA CTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTCCTGGAAGAGCAACTC TATCTGATCTCAAAATGCGTATACTGGGAACAGGATGCCTTAGCCCACAACAGAACCAGAATGAATCTTTGAAGGCACAAGACTCTGCTT TTGCCACTCTTCCTCTTTCCTGGTATAGAAGATGGATGTAGGAGAGCTTCTTTTCTAACTACCATCTGATCAGACAAGGAATGAAGCAAT GACTGTGGGCTGGGAAACTGTACCTACCTCTCTTCCCACTGCAAATTTCTGGGATAGACCAAAAGTGAATTTGATTATGTGTTGGCTGAA GTTCTTCATTCTGACTGTTGAGGGGAGGTTTTCCTTTGAAGAGTTTTCATCCCAGACTCAGCTGTCTTTTCACATGGATGAAATAATTCC TGCTACCAACAACAGAGCTTCACCAGGAAGTTGAGTTTTCAAGATGCCTTGTTGCTTTGAAGAAGGGAGTGATGTCAATTCTCTTGTTAC ATTCTCCCTTTAGCAACCTGAGTAAGAGACTCTCTGCCACTGGGCTGCAAAAAAATAAATTACTTGAATCTCCCCTTGGCCCAGGCTGAG GTACTATCTTGTCCTATACACTTCTACTTGGTCACTTTGCTTTCTTCGTTAATGGAACATACAGTAGCATGTTAAGAGGGATTTCATGTT >In-frame_STXBP6_ENST00000358326_chr14_25443871_-_ZNF410_ENST00000540593_chr14_74370663_+_1120nt GGGCGCGAGCCAGGCTGCACGATTCACTGCGTGCTGTCCTCACTTGTTCTACAATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTG CACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGAAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCG AATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTGATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAG TGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGCCAGCTCACTTTAAATACCACCTCAAGACTCATCGAA ATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGCTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATG GAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAGCTGGAAACCTGAAGAACCACCGGCGCATCCACACAG GAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGTATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAG GAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAAGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGC TGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGCTGAGCCACTAATGGGCAGTAGTTTGCTTGAAGAGGCTTCAGTACCCAGTAAAA ACCTGGTGTCTATGAATTCCCAGCCCAGCCTTGGTGGAGAGTCCTTGAACCTACCAAATACCAATTCTATCCTGGGAGTTGATGATGAGG TGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACACATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATG AAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAGATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTC >In-frame_STXBP6_ENST00000358326_chr14_25443871_-_ZNF410_ENST00000324593_chr14_74370663_+_1660nt GGGCGCGAGCCAGGCTGCACGATTCACTGCGTGCTGTCCTCACTTGTTCTACAATGAGTGCCAAATCTGCTATCAGCAAGGAAATTTTTG CACCTCTTGATGAAAGGATGCTGGGAGCTGTCCAAGTCAAGAGGAGGACAAAGAAAAAGATTCCTTTCTTGGCAACTGGAGGTCAAGGCG AATATTTAACTTATATCTGCCTGTCAGGAGAAAATGTCCACCTTGGTTCTGGTGATGGGCAGTCAAAAGATTCTGGGCCCCTTCCTCAAG TGGAAAAGAAGCTCAAGTGTACAGTTGAAGGTTGTGACCGGACATTTGTATGGCCAGCTCACTTTAAATACCACCTCAAGACTCATCGAA ATGACCGCTCCTTCATCTGTCCTGCAGAAGGTTGTGGGAAAAGCTTCTATGTGCTGCAGAGGCTGAAGGTGCACATGAGGACCCACAATG GAGAGAAGCCCTTTATGTGCCATGAGTCTGGCTGTGGTAAGCAGTTTACTACAGCTGGAAACCTGAAGAACCACCGGCGCATCCACACAG GAGAGAAACCTTTCCTTTGTGAAGCCCAAGGATGTGGCCGTTCCTTTGCTGAGTATTCTAGCCTCCGAAAACATCTGGTGGTTCACTCAG GAGAGAAGCCTCATCAGTGCCAAGTCTGTGGGAAGACCTTCTCTCAGAGTGGAAGCAGGAATGTGCATATGAGAAAGCATCACCTGCAGC TGGGAGCAGCTGGGAGTCAAGAGCAGGAGCAAACTGAGGTGCTTGCTGAAGGATCCCCACGTTCCCTGTCTTCAGTGCCTGATGTGACAC ATCACCTGGTGACCATGCAGTCAGGGAGGCAATCATATGAAGTTTCTGTCTTAACTGCAGTAAATCCACAAGAGTTACTAAACCAAGGAG ATTTAACTGAAAGACGGACATGAGCGTGGGTGCTGACTCCTGGAAGAGCAACTCTATCTGATCTCAAAATGCGTATACTGGGAACAGGAT GCCTTAGCCCACAACAGAACCAGAATGAATCTTTGAAGGCACAAGACTCTGCTTTTGCCACTCTTCCTCTTTCCTGGTATAGAAGATGGA TGTAGGAGAGCTTCTTTTCTAACTACCATCTGATCAGACAAGGAATGAAGCAATGACTGTGGGCTGGGAAACTGTACCTACCTCTCTTCC CACTGCAAATTTCTGGGATAGACCAAAAGTGAATTTGATTATGTGTTGGCTGAAGTTCTTCATTCTGACTGTTGAGGGGAGGTTTTCCTT TGAAGAGTTTTCATCCCAGACTCAGCTGTCTTTTCACATGGATGAAATAATTCCTGCTACCAACAACAGAGCTTCACCAGGAAGTTGAGT TTTCAAGATGCCTTGTTGCTTTGAAGAAGGGAGTGATGTCAATTCTCTTGTTACATTCTCCCTTTAGCAACCTGAGTAAGAGACTCTCTG CCACTGGGCTGCAAAAAAATAAATTACTTGAATCTCCCCTTGGCCCAGGCTGAGGTACTATCTTGTCCTATACACTTCTACTTGGTCACT TTGCTTTCTTCGTTAATGGAACATACAGTAGCATGTTAAGAGGGATTTCATGTTTTTGTTTTTTTAAAGTTAAAAATTACATGATGCAGA |
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FusionGenePPI for STXBP6_ZNF410 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| STXBP6 | CDH1, ALS2, STX7, STX1A, STX3, STX4, NAPG, STX8, VTI1B, STX12, ATG7, STX6, NAPA, SNAP23 | ZNF410 | POLR2M, BLZF1, APP, GOLGA2, TRAF2, MTUS2, SERTAD1, CEP70, TSGA10, ZNF397, RAB3IP, FSD2, FAM9B |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for STXBP6_ZNF410 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for STXBP6_ZNF410 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | STXBP6 | C0004352 | Autistic Disorder | 1 | CTD_human |
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