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Fusion gene ID: 36679 |
FusionGeneSummary for STXBP4_MSI2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: STXBP4_MSI2 | Fusion gene ID: 36679 | Hgene | Tgene | Gene symbol | STXBP4 | MSI2 | Gene ID | 252983 | 124540 |
| Gene name | syntaxin binding protein 4 | musashi RNA binding protein 2 | |
| Synonyms | Synip | MSI2H | |
| Cytomap | 17q22 | 17q22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | syntaxin-binding protein 4STX4-interacting proteinsyntaxin 4 interacting protein | RNA-binding protein Musashi homolog 2musashi homolog 2musashi-2 | |
| Modification date | 20180520 | 20180523 | |
| UniProtAcc | Q6ZWJ1 | Q96DH6 | |
| Ensembl transtripts involved in fusion gene | ENST00000299341, ENST00000376352, ENST00000405898, ENST00000434978, ENST00000398391, | ENST00000416426, ENST00000284073, ENST00000322684, ENST00000442934, ENST00000579180, ENST00000579505, | |
| Fusion gene scores | * DoF score | 4 X 4 X 2=32 | 23 X 13 X 8=2392 |
| # samples | 3 | 22 | |
| ** MAII score | log2(3/32*10)=-0.0931094043914815 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(22/2392*10)=-3.44264196067345 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: STXBP4 [Title/Abstract] AND MSI2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | STXBP4 | GO:0006974 | cellular response to DNA damage stimulus | 19451233 |
| Hgene | STXBP4 | GO:0061178 | regulation of insulin secretion involved in cellular response to glucose stimulus | 12855681 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A8-A09I-01A | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000299341 | ENST00000416426 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000299341 | ENST00000284073 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000299341 | ENST00000322684 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000299341 | ENST00000442934 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000299341 | ENST00000579180 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3UTR | ENST00000299341 | ENST00000579505 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| In-frame | ENST00000376352 | ENST00000416426 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| In-frame | ENST00000376352 | ENST00000284073 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| In-frame | ENST00000376352 | ENST00000322684 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| In-frame | ENST00000376352 | ENST00000442934 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| In-frame | ENST00000376352 | ENST00000579180 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| 5CDS-3UTR | ENST00000376352 | ENST00000579505 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000405898 | ENST00000416426 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000405898 | ENST00000284073 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000405898 | ENST00000322684 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000405898 | ENST00000442934 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000405898 | ENST00000579180 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3UTR | ENST00000405898 | ENST00000579505 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| In-frame | ENST00000434978 | ENST00000416426 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| In-frame | ENST00000434978 | ENST00000284073 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| In-frame | ENST00000434978 | ENST00000322684 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| In-frame | ENST00000434978 | ENST00000442934 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| In-frame | ENST00000434978 | ENST00000579180 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| 5CDS-3UTR | ENST00000434978 | ENST00000579505 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000398391 | ENST00000416426 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000398391 | ENST00000284073 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000398391 | ENST00000322684 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000398391 | ENST00000442934 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3CDS | ENST00000398391 | ENST00000579180 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
| intron-3UTR | ENST00000398391 | ENST00000579505 | STXBP4 | chr17 | 53150437 | + | MSI2 | chr17 | 55693331 | + |
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FusionProtFeatures for STXBP4_MSI2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| STXBP4 | MSI2 |
| Plays a role in the translocation of transport vesiclesfrom the cytoplasm to the plasma membrane. Inhibits thetranslocation of SLC2A4 from intracellular vesicles to the plasmamembrane by STX4A binding and preventing the interaction betweenSTX4A and VAMP2. Stimulation with insulin disrupts the interactionwith STX4A, leading to increased levels of SLC2A4 at the plasmamembrane. May also play a role in the regulation of insulinrelease by pancreatic beta cells after stimulation by glucose (Bysimilarity). {ECO:0000250}. | RNA binding protein that regulates the expression oftarget mRNAs at the translation level. May play a role in theproliferation and maintenance of stem cells in the central nervoussystem (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for STXBP4_MSI2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000416426_chr17_55693331_+_564aa MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQ RQAHGMEMDYEEVIRLLEAKITELKAQLADYSDQNKVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGF APSYGYQFPGFPAAAYGPVAAAAVAAARGSVLNSYSAQPNFGAPASPAGSNPARPGGFPGANSPGPVADLYGPASQDSGVGNYISAASPQ >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000284073_chr17_55693331_+_546aa MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQ RQAHGMEMDYEEVIRLLEAKITELKAQLADYSDQNKVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGF APSYGYQFPGFPAAAYGPVAAAAVAAARGSGSNPARPGGFPGANSPGPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIAGPLIATAF >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000322684_chr17_55693331_+_473aa MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQ RQAHGMEMDYEEVIRLLEAKITELKAQLADYSDQNKVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGF >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000442934_chr17_55693331_+_546aa MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQ RQAHGMEMDYEEVIRLLEAKITELKAQLADYSDQNKVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGF APSYGYQFPGFPAAAYGPVAAAAVAAARGSGSNPARPGGFPGANSPGPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIAGPLIATAF >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000579180_chr17_55693331_+_473aa MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQ RQAHGMEMDYEEVIRLLEAKITELKAQLADYSDQNKVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGF >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000416426_chr17_55693331_+_542aa MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEAKAVVEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAKIT ELKAQLADYSDQNKVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQFPGFPAAAYGPVAAA AVAAARGSVLNSYSAQPNFGAPASPAGSNPARPGGFPGANSPGPVADLYGPASQDSGVGNYISAASPQPGSGFGHGIAGPLIATAFTNGY >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000284073_chr17_55693331_+_524aa MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEAKAVVEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAKIT ELKAQLADYSDQNKVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQFPGFPAAAYGPVAAA >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000322684_chr17_55693331_+_451aa MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEAKAVVEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAKIT ELKAQLADYSDQNKVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQFPDYLPVSQDIIFIN >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000442934_chr17_55693331_+_524aa MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEAKAVVEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAKIT ELKAQLADYSDQNKVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQFPGFPAAAYGPVAAA >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000579180_chr17_55693331_+_451aa MNKNTSTVVSPSLLEKDPAFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSII TGAKLRLESAWEIAFIRQKSDNIQPENLSCTSLIEASGEYGPQASTLSLFSSPPEILIPKTSSTPKTNNDILSSCEIKTGYNKTVQIPIT SENSTVGLSNTDVASAWTENYGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCLQLDE VNVGAHEISNILDSQLLPCDSSEADEMERLKCERDDALKEVNTLKEAKAVVEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAKIT ELKAQLADYSDQNKVECKKAQPKEVMFPPGTRGRARGLPYTMDAFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQFPDYLPVSQDIIFIN |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000416426_chr17_55693331_+_1692nt ATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAATTGCCAAGGAAACAGGC CTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGGAGGAGACTGTTATAAG GATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGAAGCAAAAAGCATAATT ACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCCAGAAAATCTGTCATGT ACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGAAATACTAATCCCAAAG ACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGTACAGATTCCAATTACT TCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGAAAAGATCTCCCTAAAT CCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACAACACCAAGCCCTGAGA CAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTGCTTGCAGTTGGATGAA GTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGATGAAATGGAAAGGCTC AAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCAGATAAGCAAAGGAAACAATTGACAGAA GAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAG AGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGAT TATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCTGGGACAAGAGGCCGGGCCCGGGGACTG CCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCGACCTATGGCCGTGGCTACCCCGGATTT GCTCCAAGCTATGGCTATCAGTTCCCAGGCTTCCCAGCAGCGGCTTATGGACCAGTGGCAGCAGCGGCGGTGGCGGCAGCAAGAGGATCA GTCCTGAATAGCTACAGTGCTCAACCGAATTTTGGCGCGCCCGCTTCCCCGGCAGGCTCCAACCCGGCGCGGCCCGGAGGCTTCCCGGGG GCCAACAGCCCAGGACCTGTCGCCGATCTCTACGGCCCTGCCAGCCAGGACTCCGGAGTGGGGAATTACATAAGTGCGGCCAGCCCACAG >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000284073_chr17_55693331_+_1638nt ATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAATTGCCAAGGAAACAGGC CTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGGAGGAGACTGTTATAAG GATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGAAGCAAAAAGCATAATT ACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCCAGAAAATCTGTCATGT ACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGAAATACTAATCCCAAAG ACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGTACAGATTCCAATTACT TCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGAAAAGATCTCCCTAAAT CCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACAACACCAAGCCCTGAGA CAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTGCTTGCAGTTGGATGAA GTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGATGAAATGGAAAGGCTC AAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCAGATAAGCAAAGGAAACAATTGACAGAA GAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAG AGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGAT TATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCTGGGACAAGAGGCCGGGCCCGGGGACTG CCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCGACCTATGGCCGTGGCTACCCCGGATTT GCTCCAAGCTATGGCTATCAGTTCCCAGGCTTCCCAGCAGCGGCTTATGGACCAGTGGCAGCAGCGGCGGTGGCGGCAGCAAGAGGATCA GGCTCCAACCCGGCGCGGCCCGGAGGCTTCCCGGGGGCCAACAGCCCAGGACCTGTCGCCGATCTCTACGGCCCTGCCAGCCAGGACTCC GGAGTGGGGAATTACATAAGTGCGGCCAGCCCACAGCCGGGCTCGGGCTTCGGCCACGGCATAGCTGGACCTTTGATTGCAACGGCCTTT >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000322684_chr17_55693331_+_1419nt ATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAATTGCCAAGGAAACAGGC CTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGGAGGAGACTGTTATAAG GATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGAAGCAAAAAGCATAATT ACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCCAGAAAATCTGTCATGT ACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGAAATACTAATCCCAAAG ACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGTACAGATTCCAATTACT TCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGAAAAGATCTCCCTAAAT CCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACAACACCAAGCCCTGAGA CAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTGCTTGCAGTTGGATGAA GTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGATGAAATGGAAAGGCTC AAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCAGATAAGCAAAGGAAACAATTGACAGAA GAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAG AGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGAT TATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCTGGGACAAGAGGCCGGGCCCGGGGACTG CCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCGACCTATGGCCGTGGCTACCCCGGATTT >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000442934_chr17_55693331_+_1638nt ATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAATTGCCAAGGAAACAGGC CTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGGAGGAGACTGTTATAAG GATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGAAGCAAAAAGCATAATT ACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCCAGAAAATCTGTCATGT ACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGAAATACTAATCCCAAAG ACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGTACAGATTCCAATTACT TCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGAAAAGATCTCCCTAAAT CCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACAACACCAAGCCCTGAGA CAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTGCTTGCAGTTGGATGAA GTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGATGAAATGGAAAGGCTC AAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCAGATAAGCAAAGGAAACAATTGACAGAA GAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAG AGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGAT TATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCTGGGACAAGAGGCCGGGCCCGGGGACTG CCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCGACCTATGGCCGTGGCTACCCCGGATTT GCTCCAAGCTATGGCTATCAGTTCCCAGGCTTCCCAGCAGCGGCTTATGGACCAGTGGCAGCAGCGGCGGTGGCGGCAGCAAGAGGATCA GGCTCCAACCCGGCGCGGCCCGGAGGCTTCCCGGGGGCCAACAGCCCAGGACCTGTCGCCGATCTCTACGGCCCTGCCAGCCAGGACTCC GGAGTGGGGAATTACATAAGTGCGGCCAGCCCACAGCCGGGCTCGGGCTTCGGCCACGGCATAGCTGGACCTTTGATTGCAACGGCCTTT >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000579180_chr17_55693331_+_1419nt ATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAATTGCCAAGGAAACAGGC CTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGGAGGAGACTGTTATAAG GATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGAAGCAAAAAGCATAATT ACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCCAGAAAATCTGTCATGT ACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGAAATACTAATCCCAAAG ACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGTACAGATTCCAATTACT TCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGAAAAGATCTCCCTAAAT CCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACAACACCAAGCCCTGAGA CAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTGCTTGCAGTTGGATGAA GTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGATGAAATGGAAAGGCTC AAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCAGATAAGCAAAGGAAACAATTGACAGAA GAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAG AGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGAT TATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCTGGGACAAGAGGCCGGGCCCGGGGACTG CCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCGACCTATGGCCGTGGCTACCCCGGATTT >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000416426_chr17_55693331_+_1626nt ATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAATTGCCAAGGAAACAGGC CTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGGAGGAGACTGTTATAAG GATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGAAGCAAAAAGCATAATT ACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCCAGAAAATCTGTCATGT ACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGAAATACTAATCCCAAAG ACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGTACAGATTCCAATTACT TCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGAAAAGATCTCCCTAAAT CCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACAACACCAAGCCCTGAGA CAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTGCTTGCAGTTGGATGAA GTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGATGAAATGGAAAGGCTC AAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGTCGG ATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATTACA GAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCTGGG ACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCGACC TATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGGCTTCCCAGCAGCGGCTTATGGACCAGTGGCAGCAGCG GCGGTGGCGGCAGCAAGAGGATCAGTCCTGAATAGCTACAGTGCTCAACCGAATTTTGGCGCGCCCGCTTCCCCGGCAGGCTCCAACCCG GCGCGGCCCGGAGGCTTCCCGGGGGCCAACAGCCCAGGACCTGTCGCCGATCTCTACGGCCCTGCCAGCCAGGACTCCGGAGTGGGGAAT TACATAAGTGCGGCCAGCCCACAGCCGGGCTCGGGCTTCGGCCACGGCATAGCTGGACCTTTGATTGCAACGGCCTTTACAAATGGATAC >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000284073_chr17_55693331_+_1572nt ATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAATTGCCAAGGAAACAGGC CTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGGAGGAGACTGTTATAAG GATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGAAGCAAAAAGCATAATT ACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCCAGAAAATCTGTCATGT ACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGAAATACTAATCCCAAAG ACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGTACAGATTCCAATTACT TCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGAAAAGATCTCCCTAAAT CCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACAACACCAAGCCCTGAGA CAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTGCTTGCAGTTGGATGAA GTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGATGAAATGGAAAGGCTC AAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGTCGG ATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATTACA GAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCTGGG ACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCGACC TATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGGCTTCCCAGCAGCGGCTTATGGACCAGTGGCAGCAGCG GCGGTGGCGGCAGCAAGAGGATCAGGCTCCAACCCGGCGCGGCCCGGAGGCTTCCCGGGGGCCAACAGCCCAGGACCTGTCGCCGATCTC TACGGCCCTGCCAGCCAGGACTCCGGAGTGGGGAATTACATAAGTGCGGCCAGCCCACAGCCGGGCTCGGGCTTCGGCCACGGCATAGCT >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000322684_chr17_55693331_+_1353nt ATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAATTGCCAAGGAAACAGGC CTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGGAGGAGACTGTTATAAG GATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGAAGCAAAAAGCATAATT ACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCCAGAAAATCTGTCATGT ACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGAAATACTAATCCCAAAG ACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGTACAGATTCCAATTACT TCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGAAAAGATCTCCCTAAAT CCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACAACACCAAGCCCTGAGA CAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTGCTTGCAGTTGGATGAA GTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGATGAAATGGAAAGGCTC AAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGTCGG ATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATTACA GAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCTGGG ACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCGACC TATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGACTATTTGCCGGTTTCACAAGACATAATTTTTATCAAC >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000442934_chr17_55693331_+_1572nt ATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAATTGCCAAGGAAACAGGC CTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGGAGGAGACTGTTATAAG GATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGAAGCAAAAAGCATAATT ACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCCAGAAAATCTGTCATGT ACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGAAATACTAATCCCAAAG ACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGTACAGATTCCAATTACT TCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGAAAAGATCTCCCTAAAT CCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACAACACCAAGCCCTGAGA CAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTGCTTGCAGTTGGATGAA GTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGATGAAATGGAAAGGCTC AAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGTCGG ATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATTACA GAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCTGGG ACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCGACC TATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGGCTTCCCAGCAGCGGCTTATGGACCAGTGGCAGCAGCG GCGGTGGCGGCAGCAAGAGGATCAGGCTCCAACCCGGCGCGGCCCGGAGGCTTCCCGGGGGCCAACAGCCCAGGACCTGTCGCCGATCTC TACGGCCCTGCCAGCCAGGACTCCGGAGTGGGGAATTACATAAGTGCGGCCAGCCCACAGCCGGGCTCGGGCTTCGGCCACGGCATAGCT >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000579180_chr17_55693331_+_1353nt ATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAATTGCCAAGGAAACAGGC CTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGGAGGAGACTGTTATAAG GATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGAAGCAAAAAGCATAATT ACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCCAGAAAATCTGTCATGT ACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGAAATACTAATCCCAAAG ACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGTACAGATTCCAATTACT TCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGAAAAGATCTCCCTAAAT CCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACAACACCAAGCCCTGAGA CAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTGCTTGCAGTTGGATGAA GTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGATGAAATGGAAAGGCTC AAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGTCGG ATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATTACA GAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCTGGG ACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCGACC TATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGACTATTTGCCGGTTTCACAAGACATAATTTTTATCAAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000416426_chr17_55693331_+_2503nt AGGTGGCAGCGCTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAG AGTAATATAGGATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGT TAAATCCAAGGCTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAG ATGATTACAATTGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAA ATTATTCCTGGAGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTA TCATTTGAAGAAGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGAC AACATTCAGCCAGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCT TCTCCTCCTGAAATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATAC AACAAAACAGTACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTAT GGGCTACAAGAAAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCC ACAAAGGAACAACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGA AACTTGTTTTGCTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCT TCAGAAGCAGATGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCA GATAAGCAAAGGAAACAATTGACAGAAGAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGT CGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATT ACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCT GGGACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCG ACCTATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGGCTTCCCAGCAGCGGCTTATGGACCAGTGGCAGCA GCGGCGGTGGCGGCAGCAAGAGGATCAGTCCTGAATAGCTACAGTGCTCAACCGAATTTTGGCGCGCCCGCTTCCCCGGCAGGCTCCAAC CCGGCGCGGCCCGGAGGCTTCCCGGGGGCCAACAGCCCAGGACCTGTCGCCGATCTCTACGGCCCTGCCAGCCAGGACTCCGGAGTGGGG AATTACATAAGTGCGGCCAGCCCACAGCCGGGCTCGGGCTTCGGCCACGGCATAGCTGGACCTTTGATTGCAACGGCCTTTACAAATGGA TACCATTGAGCAGGTGCTTTCGTTGCCATCTCACTCTGAGAGCATACCTGGATGTCCAGGCAAGACTGGGCGAAGTTTCTGAGTGGCCCT TTGTTTAGGTGATGTCCTCAGACCTGGACCCCCACCAGCCTCACTCCCCATCCCAACCAGAGATGGCTCACTTCGGATCGAGGGTTGACT ACATCTCATCATCTCACGAATCTGCTGTAATATAAGACAACAGCTTTTAAATGTGTATATAACCCATGATTTCGGTTTTGTTTTGTTTTG TTTTTCTTGATGGTTTCCCTCTCCCTCCCTCTCTTCCCATTCTCCTTTTAAATCTCTTTGAATCACATTTGGTAGTGATTTTGACTTAGT CCAGTAGTCACATAGCTTTAATATCTAGTTCAAAGCTAACCATAGTATAATTGTTATATTAAGGAGTTATTTTTTCTTAAAACATTTTTT TTTGCTTGTTTTGGTTCTGTTCTCACTTTTAAAGGATGCTGAGATGGTAATATGACTCTCCATATTTTGGTACCAATTCTGAGACTGTAT >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000284073_chr17_55693331_+_7013nt AGGTGGCAGCGCTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAG AGTAATATAGGATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGT TAAATCCAAGGCTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAG ATGATTACAATTGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAA ATTATTCCTGGAGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTA TCATTTGAAGAAGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGAC AACATTCAGCCAGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCT TCTCCTCCTGAAATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATAC AACAAAACAGTACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTAT GGGCTACAAGAAAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCC ACAAAGGAACAACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGA AACTTGTTTTGCTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCT TCAGAAGCAGATGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCA GATAAGCAAAGGAAACAATTGACAGAAGAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGT CGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATT ACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCT GGGACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCG ACCTATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGGCTTCCCAGCAGCGGCTTATGGACCAGTGGCAGCA GCGGCGGTGGCGGCAGCAAGAGGATCAGGCTCCAACCCGGCGCGGCCCGGAGGCTTCCCGGGGGCCAACAGCCCAGGACCTGTCGCCGAT CTCTACGGCCCTGCCAGCCAGGACTCCGGAGTGGGGAATTACATAAGTGCGGCCAGCCCACAGCCGGGCTCGGGCTTCGGCCACGGCATA GCTGGACCTTTGATTGCAACGGCCTTTACAAATGGATACCATTGAGCAGGTGCTTTCGTTGCCATCTCACTCTGAGAGCATACCTGGATG TCCAGGCAAGACTGGGCGAAGTTTCTGAGTGGCCCTTTGTTTAGGTGATGTCCTCAGACCTGGACCCCCACCAGCCTCACTCCCCATCCC AACCAGAGATGGCTCACTTCGGATCGAGGGTTGACTACATCTCATCATCTCACGAATCTGCTGTAATATAAGACAACAGCTTTTAAATGT GTATATAACCCATGATTTCGGTTTTGTTTTGTTTTGTTTTTCTTGATGGTTTCCCTCTCCCTCCCTCTCTTCCCATTCTCCTTTTAAATC TCTTTGAATCACATTTGGTAGTGATTTTGACTTAGTCCAGTAGTCACATAGCTTTAATATCTAGTTCAAAGCTAACCATAGTATAATTGT TATATTAAGGAGTTATTTTTTCTTAAAACATTTTTTTTTGCTTGTTTTGGTTCTGTTCTCACTTTTAAAGGATGCTGAGATGGTAATATG ACTCTCCATATTTTGGTACCAATTCTGAGACTGTATGAATTTTCAGGTGGAACTTTAGCACACACTGAAGCAAAGTTGTGAAGTGCAGGG CGGGAGGTGGGCGTGAGCTTTCTATTTTGCGTTGTAGAAGAAGTGAGATGTAGTAAGCTAATTAACAGACTTTCTAGCAGTTCTTTTTGT GATGTCTCTTTGTTAATCTGAGTCTATCTATTTTCGGCAATAAGGTAAGGACGACAGTGTTTTGAGTGTCCTCCTTTTCTATAAGTGCTT TTTTTCTGTTGAAAGAGGTGATATTATAAGGTTTTTTGAAATTGTGAATTCTAAAAAAGAAATGTTGTAAATACAATTCCATTAACTACA TAGAAACTATTAAGAAAGAGAGAATCAAAAATATTTTTGTGAGGGAGTCGGTCCCAGGCAGTTTGATGCTCTGTGGAAGGAGGCGGGAAG GGAACGTTGGCCAAGTCAGTTACTGAGATGAAGATCGCCCAGCTGCCAGGACCACCCCAGGACAAGTTAGAGCACTGTTTAGCTCCTTTG TCTGTGTGATAGACCTAAGAACTGTATTAGTGTTGTACCAGCCTATTAACCTCTTGTCTGTGCACAGCTTCAAATGTTACCGTCTAGTTA GATTTTTATTTAAAATATGAAAAACTGCTTTTCCCAAGATGTTTTTTAAAAACAAAGCTACAATTTTAATATTTAACATATTTAAAGTTT CAAAGCACACCTGTTTGGCTTGGGTGGGGGTGGGGTGGGGGGGACATTCTTTTTCAGTCTTAATTTTTAAATATTTGATCATTTTCTATT GTCCAATCATTTCAGCACCTCCAAAGGTCCCTAGGACACTTTGCCTCTCTTCTCCCCCTGCCCCCCACCCTGCTCCCACATCTGGGGGCC CATGGGCCAGGAGTGGATAAGCCTGCATTAATACAACCTTTCTCCATTCACTTTCTATTTACAAATTAGGAAAGCAACCTTTTGGTTTAT ATATATTTTTTTTAATACCTCAGTGCTGCAAGTATCACCAGAGAGGCTATGGAAGAATTTTTTTTTAATTTATTGTAGATGTAAACAGAA TTTTAAAAATAAAAAGTATAAACATCACTGCACTGTGACTGGTGGGAAAAACTGACAGTTTCCTCTTTGCACATGTTTAACATTTGGCTG TTATAATATATGGTCCTCGGTTGGGGAAAGATACTTATGATGAAGGATATTTTTTAATTTAACTTTTTTTTAAATATTGGTAATAGGTCG GCAACAGCAACTATAGAAGTACAACTCAATAGATGGCATTAAAACATATTGTAGTGTGGATATATATTTTTTCTTTTTTAAAATGTGATA TTGACGTTTTATTAATATTTTTTAAATTGTTACGTTTATAAATTTGGTACTTAAGGCACAGCCAGTATGAGACACTGAATGCGACATTTA TTATAAAGAGCTGCTGCACTCCTATTTTTATAAATTTTACTAACAAAGTAGACTAATGTAGACATTCACAGACATGGTAGGGCAAAAGCA TCTTCAAACTAAAGACTCCAAAATGCTAACTCAGAAAGAAAGAAAAAACCCGTTTTCAATTCTAATGAAACAGCAACAACATTTTTTTTA ATTAAAAAAAAAATCATGTTCTTTGTTTTTCTAATAAAATGTTAGGTTGTTTGGTGAGGTTTTTTTGTTGTTTTTTTCCTTTCTTTGTTT CTTTTCTTTTCCCCCAAACAACCAGATTAAATGCTGAGCGCTTTTAAAATATCAAAACTTGTTCAAGTCATAAAACAACAAAACATAAGT TTTATTTAAAAAAAAAAAAAGAAAGAAAAAATAGTAAATTCCCAGAAATTCAGTGTTTAGACGAGGGAATTTAATTCCTATTTTGTCCAT GTTGGTGATGTACTGTACTTCCCTTCCTTTTCTCTGCATCCCCCATCACCTCATAGAAGACTCTTTGTTGATCATTGTATGTTAATAATG TATAAAATGGCTATCTTGTAAGCGTGCTGTCCTGGTACTAGTGTAGCGACTTTTTTTCTCCTCTTTCTTCTAGTACATATTGATAGGTAT AACATAATTAAGGTTTAAAAAAAATTAGACATAGTTATTCAGATTTAGGACCAGTAAGGATAGAACTTTCTCTTATTTATGAAAAAAAAT GCTAATAATTTTGGGGCAGTTTTTTCCTTTAATTATTTTTTTCAATTTCAAGTTTAATTTTATTTTAGCTGATCTGATGTGGTTTCAACT AACCCAAGGTCTCACCATGTTAAAATGCCGGCGGACTCTACGGCGTTTTGTAGATCCCCCCCCCCCCACCCACTGTGAAGGGGTGCCATA CTACCTTAAATGCTAATGCTAGATATGCAAAACTGGATTTTTTTAATTTATTTTTTAAAAGAGGGAGGCATGGTATATTAAAATGATTTT ACTAAGAGAAAAAATATTTTTTTAAGAATGCTCAGAAGAAATTGATAATCTGTGTGAATATGTTTTAGATGTTTATATACCTTTTGAAGA GACCCAGTAGCCCATAGCACAAATCTTGTGGAAATCCGATATGTTTTAATGTGGCTACCTAGGTTTAAGGTTCACGTTAGTCCCCCCATT CCATCTAGAAGTCCATTTTGAAAGATTTTTGTAAATTCTTTTAACACTGATGTTTCAGCCTCGTCTTTGTTTCAGTTAAGCTCAATGGCG AACATGGGAACCACCTTTCGCCTTCCCTGGGGGAGAAACCCTCTTGGCTGATGGCTTTTCCCCGGAATTATCAAACAGCCACCGGGTGAC TTTCTGGCTTCCAGATCCATCTGCCTGAGACCCCCGAACTCCTCTCCTCCCAAGCAGAGGCGAGTGAGTGGCATTAGCTCCCGGACCCAT TCCCGGTCCTAGCTGGGCATGGGGCTGACGGAGATGACCAAGCCTTGGTCTGCTCTCTAGCAGCTTCCACAGACTTGGCTCGTGGCCTTC CTTATATCCACTGGGAACAAACAGCCTCGCGCTCTATACCAAACAGCCTCGCGCTCTATCCCAGTCGCCCATTAGCTTGATTCAAACAAA GCCCCAGCAGGCCTTTGCGTTTTTATCCTTCATAACCTTCATCTTAATTTGAACTTGTAGCTTGGACTTTAAGGTAGCATGGCTCTATTG CTGTCAATTTACTGTTTCACTGCACAGCAATCACAGCCAGTGAATGTTACACACATCTTGCTAGACTAGTATAAAAATCATTGGGTAATT GTTGGTTCTAATGACCTGAAAGGTGTTCAGTTTTTGTTCTTGGTTTTGTTTTGTTTTTGATTTCTTGGGGGTGGGTTTTGCTTGTTGTTC CTTTTCATTTGGGGGTTTTTGGGGAAAAAATTTATTTTTGGTTCCAAATAGAAAAACAAAACCTATTTTGATCTTTAGTGCAAACGAGGG CTAGGGACTTAGCCTCCTCCACCACCTCCACACTGCTTCATTCTGCCATTCACTCACTGCAGCATATTCAAGAATAAAGCAATATCGTTT ACTACATTTTTTATTGAAGGTCAGCCATGCTTTCTGTATTATATTGCATATGAAATTGTTTACAAAAGAAACACTAACTCATACTTCTCT TTATTGGTTGCAAGTGGCACGCAGGAACAGAGGGAGAGTGGGGGGCTGGTGGGGGAGGGGAGATTTTTTTTTTTTTTTCTTGAATGTGCT TCGCAAGCCAGGCTATCTTCCAAGGAAGGCAGACAGTGGGAGAGCAGAGGGACTGACTGCAGGCAAGCACATTGAAGAAAGACACTGGCG GGTTTCCCCACCCTCACCCCAAAGCAGAAAACTAGCAGACGTCAGCTCAGCCCCGTCCTGGGCACAGACACTACACAAGGAGACGCTGGA AGTTAAGCAATACTTTAATACTGTAATATGTTTGTTTTCTTTTTCTTTCTTTTTTTTCTACCAAAAAAAAGTAAGTAAACTAAAACACAA AAACATATAAATAAAATCCATCCCTCTTGTCGGGGACCTGCAGGGGGGCAACCTTAATCCAAACACCTGGCTATCAAATAATCAGAATGT ATTGTCTCAGACAGGATTTCAGTTCCGGGAGGCAGGGGCATGATGGGGGAGGGGGCCGGAGGCTGAGAGACAAAAGTTCCAGAGCCTCCC TCGAAGGTTCTCTACTACTGTATTCTGTACATAATGTACCATCCCATGTGGAATCTGTGAGTGTCCTCTTAAGTAGCGTGGGCTAGCCAA TCTGCCGTTCATGGTGTATTGTAAACTCCGAATTCCATATGTAATAGGATGCAAGTCTAAGCGTTTCATGTGGACATAAATGTATCTAAA TAAAACTTTCCCTAGCACTGTGGCTGACCTCACCCTTACTTTTATACTTTAGTATGAAACTGATGAGAACTTTGGTAGTGAGTATTTTTT TTATATATATACATATATATGTACTATCTATATATATATCTCAAGCATCTTTCAGGTCTTTGTGTGTGGCTTTCTTAAAGCCCTGTTGTA AAAAATTACTATGTGGATGGCAGTCTCTCACATCACAGATGTGGAAAGTATAATTTTATATTTGTATTTTCAAATAAATAAGTTTGTGAA >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000322684_chr17_55693331_+_2695nt AGGTGGCAGCGCTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAG AGTAATATAGGATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGT TAAATCCAAGGCTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAG ATGATTACAATTGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAA ATTATTCCTGGAGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTA TCATTTGAAGAAGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGAC AACATTCAGCCAGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCT TCTCCTCCTGAAATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATAC AACAAAACAGTACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTAT GGGCTACAAGAAAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCC ACAAAGGAACAACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGA AACTTGTTTTGCTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCT TCAGAAGCAGATGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCA GATAAGCAAAGGAAACAATTGACAGAAGAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGT CGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATT ACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCT GGGACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCG ACCTATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGACTATTTGCCGGTTTCACAAGACATAATTTTTATC AACTAGCTCTTAAGAGAGGCATAGCAAAGTGGGGGTTGCTACCATTTCTAGAGAGAGAGGACACAGTCCCGGCCTGGGCTGCCCCCGCTC CAGTCAATGCTCACTGAAAGTCTGTCTTAGCTGCCTGTTTGAATGACTGTTCTTTTTCTCATTTTTAATTCTTGGACTCATGTCCTCATT GCTTCACTCAATTAAAAAAAAATTATTCTCCAGTCCCCTCCCACTTTGCTTCTTGTATGCATTGTGACCGACCCCACTTCCTCAGAATGT AACGGGGCCAGAGGGAAACTTCTCACAAACTTCGTAGAGCCTCCTCAGGGGAAGCTAGGAAGAAGACATCAAATGTTTTTAAGTCATGAC CAAACAGGCTTGTTGGGGACATATCATGGGGTGAGCTTTGAAGTGCTGGTGGTCCAGAGGGGTTGCAGATACGTGACTTGGAGCACCCGT GTCTTACGATGGACAGTGATAAAGGTGAACACACAGAGACAGACTATTCTCTAAGAATGTGAGAAACCTGATCTGGAAGAGGAGCTATAT AAACACTATCTGACTATCTTTGTCTTTTGGGGCCAGTGGCTGTTGGCATAATCACAAGCCTGTCTGTCTTCGAGAAGGGACAGTGGAGTC ATCCAGGTGCTGCCACATGACAGGCACGGTGGGCACCGATCCACAGTGGGCCCCGCCTTCCCCAGCTCGCCTCCCTGCCTGTGCTGGCCT GGCCTTGCCTGCTGGCACCATTGGAGTAGGAGGGGGTGGAACACAGGGGGCCCATCCTGATCAGGCCCCATCTCAAGGTTGGCACTCCTG CCCATCACCCTTAGAAGGATCTTTTCCCATGGCTTGACTTCCTTCATTTCCCTAACTGAAATACACCCACTCTCTTGGAATAATGACGTA CCACTCAGTTGGACCCTCAAGAGTCACTGCTTTGTCTGTGCTGGTAGTTTGTGAGAAGTGACCCGCACGCTTCCATTTGATGCATTTGAT >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000442934_chr17_55693331_+_2625nt AGGTGGCAGCGCTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAG AGTAATATAGGATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGT TAAATCCAAGGCTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAG ATGATTACAATTGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAA ATTATTCCTGGAGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTA TCATTTGAAGAAGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGAC AACATTCAGCCAGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCT TCTCCTCCTGAAATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATAC AACAAAACAGTACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTAT GGGCTACAAGAAAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCC ACAAAGGAACAACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGA AACTTGTTTTGCTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCT TCAGAAGCAGATGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCA GATAAGCAAAGGAAACAATTGACAGAAGAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGT CGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATT ACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCT GGGACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCG ACCTATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGGCTTCCCAGCAGCGGCTTATGGACCAGTGGCAGCA GCGGCGGTGGCGGCAGCAAGAGGATCAGGCTCCAACCCGGCGCGGCCCGGAGGCTTCCCGGGGGCCAACAGCCCAGGACCTGTCGCCGAT CTCTACGGCCCTGCCAGCCAGGACTCCGGAGTGGGGAATTACATAAGTGCGGCCAGCCCACAGCCGGGCTCGGGCTTCGGCCACGGCATA GCTGGACCTTTGATTGCAACGGCCTTTACAAATGGATACCATTGAGCAGGTGCTTTCGTTGCCATCTCACTCTGAGAGCATACCTGGATG TCCAGGCAAGACTGGGCGAAGTTTCTGAGTGGCCCTTTGTTTAGGTGATGTCCTCAGACCTGGACCCCCACCAGCCTCACTCCCCATCCC AACCAGAGATGGCTCACTTCGGATCGAGGGTTGACTACATCTCATCATCTCACGAATCTGCTGTAATATAAGACAACAGCTTTTAAATGT GTATATAACCCATGATTTCGGTTTTGTTTTGTTTTGTTTTTCTTGATGGTTTCCCTCTCCCTCCCTCTCTTCCCATTCTCCTTTTAAATC TCTTTGAATCACATTTGGTAGTGATTTTGACTTAGTCCAGTAGTCACATAGCTTTAATATCTAGTTCAAAGCTAACCATAGTATAATTGT TATATTAAGGAGTTATTTTTTCTTAAAACATTTTTTTTTGCTTGTTTTGGTTCTGTTCTCACTTTTAAAGGATGCTGAGATGGTAATATG ACTCTCCATATTTTGGTACCAATTCTGAGACTGTATGAATTTTCAGGTGGAACTTTAGCACACACTGAAGCAAAGTTGTGAAGTGCAGGG CGGGAGGTGGGCGTGAGCTTTCTATTTTGCGTTGTAGAAGAAGTGAGATGTAGTAAGCTAATTAACAGACTTTCTAGCAGTTCTTTTTGT GATGTCTCTTTGTTAATCTGAGTCTATCTATTTTCGGCAATAAGGTAAGGACGACAGTGTTTTGAGTGTCCTCCTTTTCTATAAGTGCTT >In-frame_STXBP4_ENST00000376352_chr17_53150437_+_MSI2_ENST00000579180_chr17_55693331_+_2700nt AGGTGGCAGCGCTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAG AGTAATATAGGATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGT TAAATCCAAGGCTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAG ATGATTACAATTGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAA ATTATTCCTGGAGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTA TCATTTGAAGAAGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGAC AACATTCAGCCAGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCT TCTCCTCCTGAAATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATAC AACAAAACAGTACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTAT GGGCTACAAGAAAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCC ACAAAGGAACAACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGA AACTTGTTTTGCTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCT TCAGAAGCAGATGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAAAATTATTGGAATCA GATAAGCAAAGGAAACAATTGACAGAAGAGCTCCAGAATGTGAAACAAGAAGCCAAAGCTGTAGTTGAAGAAACAAGAGCCCTGCGTAGT CGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTTAGAGGCCAAGATT ACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGTCATGTTCCCACCT GGGACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCCCAACTTCGTGGCG ACCTATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGACTATTTGCCGGTTTCACAAGACATAATTTTTATC AACTAGCTCTTAAGAGAGGCATAGCAAAGTGGGGGTTGCTACCATTTCTAGAGAGAGAGGACACAGTCCCGGCCTGGGCTGCCCCCGCTC CAGTCAATGCTCACTGAAAGTCTGTCTTAGCTGCCTGTTTGAATGACTGTTCTTTTTCTCATTTTTAATTCTTGGACTCATGTCCTCATT GCTTCACTCAATTAAAAAAAAATTATTCTCCAGTCCCCTCCCACTTTGCTTCTTGTATGCATTGTGACCGACCCCACTTCCTCAGAATGT AACGGGGCCAGAGGGAAACTTCTCACAAACTTCGTAGAGCCTCCTCAGGGGAAGCTAGGAAGAAGACATCAAATGTTTTTAAGTCATGAC CAAACAGGCTTGTTGGGGACATATCATGGGGTGAGCTTTGAAGTGCTGGTGGTCCAGAGGGGTTGCAGATACGTGACTTGGAGCACCCGT GTCTTACGATGGACAGTGATAAAGGTGAACACACAGAGACAGACTATTCTCTAAGAATGTGAGAAACCTGATCTGGAAGAGGAGCTATAT AAACACTATCTGACTATCTTTGTCTTTTGGGGCCAGTGGCTGTTGGCATAATCACAAGCCTGTCTGTCTTCGAGAAGGGACAGTGGAGTC ATCCAGGTGCTGCCACATGACAGGCACGGTGGGCACCGATCCACAGTGGGCCCCGCCTTCCCCAGCTCGCCTCCCTGCCTGTGCTGGCCT GGCCTTGCCTGCTGGCACCATTGGAGTAGGAGGGGGTGGAACACAGGGGGCCCATCCTGATCAGGCCCCATCTCAAGGTTGGCACTCCTG CCCATCACCCTTAGAAGGATCTTTTCCCATGGCTTGACTTCCTTCATTTCCCTAACTGAAATACACCCACTCTCTTGGAATAATGACGTA CCACTCAGTTGGACCCTCAAGAGTCACTGCTTTGTCTGTGCTGGTAGTTTGTGAGAAGTGACCCGCACGCTTCCATTTGATGCATTTGAT GTGAGTGAATCCATACATTTGAATGTCATTGTCCTTGAGACCCTACATGTGCAGTTTGGCTCATCTCATTAAAGATGCTTGATGTAATAA >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000416426_chr17_55693331_+_2426nt CTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAGAGTAATATAGG ATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGTTAAATCCAAGG CTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAAT TGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGG AGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGA AGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCC AGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGA AATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGT ACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGA AAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACA ACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTG CTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGA TGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAG AGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTT AGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGT CATGTTCCCACCTGGGACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCC CAACTTCGTGGCGACCTATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGGCTTCCCAGCAGCGGCTTATGG ACCAGTGGCAGCAGCGGCGGTGGCGGCAGCAAGAGGATCAGTCCTGAATAGCTACAGTGCTCAACCGAATTTTGGCGCGCCCGCTTCCCC GGCAGGCTCCAACCCGGCGCGGCCCGGAGGCTTCCCGGGGGCCAACAGCCCAGGACCTGTCGCCGATCTCTACGGCCCTGCCAGCCAGGA CTCCGGAGTGGGGAATTACATAAGTGCGGCCAGCCCACAGCCGGGCTCGGGCTTCGGCCACGGCATAGCTGGACCTTTGATTGCAACGGC CTTTACAAATGGATACCATTGAGCAGGTGCTTTCGTTGCCATCTCACTCTGAGAGCATACCTGGATGTCCAGGCAAGACTGGGCGAAGTT TCTGAGTGGCCCTTTGTTTAGGTGATGTCCTCAGACCTGGACCCCCACCAGCCTCACTCCCCATCCCAACCAGAGATGGCTCACTTCGGA TCGAGGGTTGACTACATCTCATCATCTCACGAATCTGCTGTAATATAAGACAACAGCTTTTAAATGTGTATATAACCCATGATTTCGGTT TTGTTTTGTTTTGTTTTTCTTGATGGTTTCCCTCTCCCTCCCTCTCTTCCCATTCTCCTTTTAAATCTCTTTGAATCACATTTGGTAGTG ATTTTGACTTAGTCCAGTAGTCACATAGCTTTAATATCTAGTTCAAAGCTAACCATAGTATAATTGTTATATTAAGGAGTTATTTTTTCT TAAAACATTTTTTTTTGCTTGTTTTGGTTCTGTTCTCACTTTTAAAGGATGCTGAGATGGTAATATGACTCTCCATATTTTGGTACCAAT >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000284073_chr17_55693331_+_6936nt CTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAGAGTAATATAGG ATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGTTAAATCCAAGG CTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAAT TGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGG AGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGA AGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCC AGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGA AATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGT ACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGA AAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACA ACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTG CTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGA TGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAG AGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTT AGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGT CATGTTCCCACCTGGGACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCC CAACTTCGTGGCGACCTATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGGCTTCCCAGCAGCGGCTTATGG ACCAGTGGCAGCAGCGGCGGTGGCGGCAGCAAGAGGATCAGGCTCCAACCCGGCGCGGCCCGGAGGCTTCCCGGGGGCCAACAGCCCAGG ACCTGTCGCCGATCTCTACGGCCCTGCCAGCCAGGACTCCGGAGTGGGGAATTACATAAGTGCGGCCAGCCCACAGCCGGGCTCGGGCTT CGGCCACGGCATAGCTGGACCTTTGATTGCAACGGCCTTTACAAATGGATACCATTGAGCAGGTGCTTTCGTTGCCATCTCACTCTGAGA GCATACCTGGATGTCCAGGCAAGACTGGGCGAAGTTTCTGAGTGGCCCTTTGTTTAGGTGATGTCCTCAGACCTGGACCCCCACCAGCCT CACTCCCCATCCCAACCAGAGATGGCTCACTTCGGATCGAGGGTTGACTACATCTCATCATCTCACGAATCTGCTGTAATATAAGACAAC AGCTTTTAAATGTGTATATAACCCATGATTTCGGTTTTGTTTTGTTTTGTTTTTCTTGATGGTTTCCCTCTCCCTCCCTCTCTTCCCATT CTCCTTTTAAATCTCTTTGAATCACATTTGGTAGTGATTTTGACTTAGTCCAGTAGTCACATAGCTTTAATATCTAGTTCAAAGCTAACC ATAGTATAATTGTTATATTAAGGAGTTATTTTTTCTTAAAACATTTTTTTTTGCTTGTTTTGGTTCTGTTCTCACTTTTAAAGGATGCTG AGATGGTAATATGACTCTCCATATTTTGGTACCAATTCTGAGACTGTATGAATTTTCAGGTGGAACTTTAGCACACACTGAAGCAAAGTT GTGAAGTGCAGGGCGGGAGGTGGGCGTGAGCTTTCTATTTTGCGTTGTAGAAGAAGTGAGATGTAGTAAGCTAATTAACAGACTTTCTAG CAGTTCTTTTTGTGATGTCTCTTTGTTAATCTGAGTCTATCTATTTTCGGCAATAAGGTAAGGACGACAGTGTTTTGAGTGTCCTCCTTT TCTATAAGTGCTTTTTTTCTGTTGAAAGAGGTGATATTATAAGGTTTTTTGAAATTGTGAATTCTAAAAAAGAAATGTTGTAAATACAAT TCCATTAACTACATAGAAACTATTAAGAAAGAGAGAATCAAAAATATTTTTGTGAGGGAGTCGGTCCCAGGCAGTTTGATGCTCTGTGGA AGGAGGCGGGAAGGGAACGTTGGCCAAGTCAGTTACTGAGATGAAGATCGCCCAGCTGCCAGGACCACCCCAGGACAAGTTAGAGCACTG TTTAGCTCCTTTGTCTGTGTGATAGACCTAAGAACTGTATTAGTGTTGTACCAGCCTATTAACCTCTTGTCTGTGCACAGCTTCAAATGT TACCGTCTAGTTAGATTTTTATTTAAAATATGAAAAACTGCTTTTCCCAAGATGTTTTTTAAAAACAAAGCTACAATTTTAATATTTAAC ATATTTAAAGTTTCAAAGCACACCTGTTTGGCTTGGGTGGGGGTGGGGTGGGGGGGACATTCTTTTTCAGTCTTAATTTTTAAATATTTG ATCATTTTCTATTGTCCAATCATTTCAGCACCTCCAAAGGTCCCTAGGACACTTTGCCTCTCTTCTCCCCCTGCCCCCCACCCTGCTCCC ACATCTGGGGGCCCATGGGCCAGGAGTGGATAAGCCTGCATTAATACAACCTTTCTCCATTCACTTTCTATTTACAAATTAGGAAAGCAA CCTTTTGGTTTATATATATTTTTTTTAATACCTCAGTGCTGCAAGTATCACCAGAGAGGCTATGGAAGAATTTTTTTTTAATTTATTGTA GATGTAAACAGAATTTTAAAAATAAAAAGTATAAACATCACTGCACTGTGACTGGTGGGAAAAACTGACAGTTTCCTCTTTGCACATGTT TAACATTTGGCTGTTATAATATATGGTCCTCGGTTGGGGAAAGATACTTATGATGAAGGATATTTTTTAATTTAACTTTTTTTTAAATAT TGGTAATAGGTCGGCAACAGCAACTATAGAAGTACAACTCAATAGATGGCATTAAAACATATTGTAGTGTGGATATATATTTTTTCTTTT TTAAAATGTGATATTGACGTTTTATTAATATTTTTTAAATTGTTACGTTTATAAATTTGGTACTTAAGGCACAGCCAGTATGAGACACTG AATGCGACATTTATTATAAAGAGCTGCTGCACTCCTATTTTTATAAATTTTACTAACAAAGTAGACTAATGTAGACATTCACAGACATGG TAGGGCAAAAGCATCTTCAAACTAAAGACTCCAAAATGCTAACTCAGAAAGAAAGAAAAAACCCGTTTTCAATTCTAATGAAACAGCAAC AACATTTTTTTTAATTAAAAAAAAAATCATGTTCTTTGTTTTTCTAATAAAATGTTAGGTTGTTTGGTGAGGTTTTTTTGTTGTTTTTTT CCTTTCTTTGTTTCTTTTCTTTTCCCCCAAACAACCAGATTAAATGCTGAGCGCTTTTAAAATATCAAAACTTGTTCAAGTCATAAAACA ACAAAACATAAGTTTTATTTAAAAAAAAAAAAAGAAAGAAAAAATAGTAAATTCCCAGAAATTCAGTGTTTAGACGAGGGAATTTAATTC CTATTTTGTCCATGTTGGTGATGTACTGTACTTCCCTTCCTTTTCTCTGCATCCCCCATCACCTCATAGAAGACTCTTTGTTGATCATTG TATGTTAATAATGTATAAAATGGCTATCTTGTAAGCGTGCTGTCCTGGTACTAGTGTAGCGACTTTTTTTCTCCTCTTTCTTCTAGTACA TATTGATAGGTATAACATAATTAAGGTTTAAAAAAAATTAGACATAGTTATTCAGATTTAGGACCAGTAAGGATAGAACTTTCTCTTATT TATGAAAAAAAATGCTAATAATTTTGGGGCAGTTTTTTCCTTTAATTATTTTTTTCAATTTCAAGTTTAATTTTATTTTAGCTGATCTGA TGTGGTTTCAACTAACCCAAGGTCTCACCATGTTAAAATGCCGGCGGACTCTACGGCGTTTTGTAGATCCCCCCCCCCCCACCCACTGTG AAGGGGTGCCATACTACCTTAAATGCTAATGCTAGATATGCAAAACTGGATTTTTTTAATTTATTTTTTAAAAGAGGGAGGCATGGTATA TTAAAATGATTTTACTAAGAGAAAAAATATTTTTTTAAGAATGCTCAGAAGAAATTGATAATCTGTGTGAATATGTTTTAGATGTTTATA TACCTTTTGAAGAGACCCAGTAGCCCATAGCACAAATCTTGTGGAAATCCGATATGTTTTAATGTGGCTACCTAGGTTTAAGGTTCACGT TAGTCCCCCCATTCCATCTAGAAGTCCATTTTGAAAGATTTTTGTAAATTCTTTTAACACTGATGTTTCAGCCTCGTCTTTGTTTCAGTT AAGCTCAATGGCGAACATGGGAACCACCTTTCGCCTTCCCTGGGGGAGAAACCCTCTTGGCTGATGGCTTTTCCCCGGAATTATCAAACA GCCACCGGGTGACTTTCTGGCTTCCAGATCCATCTGCCTGAGACCCCCGAACTCCTCTCCTCCCAAGCAGAGGCGAGTGAGTGGCATTAG CTCCCGGACCCATTCCCGGTCCTAGCTGGGCATGGGGCTGACGGAGATGACCAAGCCTTGGTCTGCTCTCTAGCAGCTTCCACAGACTTG GCTCGTGGCCTTCCTTATATCCACTGGGAACAAACAGCCTCGCGCTCTATACCAAACAGCCTCGCGCTCTATCCCAGTCGCCCATTAGCT TGATTCAAACAAAGCCCCAGCAGGCCTTTGCGTTTTTATCCTTCATAACCTTCATCTTAATTTGAACTTGTAGCTTGGACTTTAAGGTAG CATGGCTCTATTGCTGTCAATTTACTGTTTCACTGCACAGCAATCACAGCCAGTGAATGTTACACACATCTTGCTAGACTAGTATAAAAA TCATTGGGTAATTGTTGGTTCTAATGACCTGAAAGGTGTTCAGTTTTTGTTCTTGGTTTTGTTTTGTTTTTGATTTCTTGGGGGTGGGTT TTGCTTGTTGTTCCTTTTCATTTGGGGGTTTTTGGGGAAAAAATTTATTTTTGGTTCCAAATAGAAAAACAAAACCTATTTTGATCTTTA GTGCAAACGAGGGCTAGGGACTTAGCCTCCTCCACCACCTCCACACTGCTTCATTCTGCCATTCACTCACTGCAGCATATTCAAGAATAA AGCAATATCGTTTACTACATTTTTTATTGAAGGTCAGCCATGCTTTCTGTATTATATTGCATATGAAATTGTTTACAAAAGAAACACTAA CTCATACTTCTCTTTATTGGTTGCAAGTGGCACGCAGGAACAGAGGGAGAGTGGGGGGCTGGTGGGGGAGGGGAGATTTTTTTTTTTTTT TCTTGAATGTGCTTCGCAAGCCAGGCTATCTTCCAAGGAAGGCAGACAGTGGGAGAGCAGAGGGACTGACTGCAGGCAAGCACATTGAAG AAAGACACTGGCGGGTTTCCCCACCCTCACCCCAAAGCAGAAAACTAGCAGACGTCAGCTCAGCCCCGTCCTGGGCACAGACACTACACA AGGAGACGCTGGAAGTTAAGCAATACTTTAATACTGTAATATGTTTGTTTTCTTTTTCTTTCTTTTTTTTCTACCAAAAAAAAGTAAGTA AACTAAAACACAAAAACATATAAATAAAATCCATCCCTCTTGTCGGGGACCTGCAGGGGGGCAACCTTAATCCAAACACCTGGCTATCAA ATAATCAGAATGTATTGTCTCAGACAGGATTTCAGTTCCGGGAGGCAGGGGCATGATGGGGGAGGGGGCCGGAGGCTGAGAGACAAAAGT TCCAGAGCCTCCCTCGAAGGTTCTCTACTACTGTATTCTGTACATAATGTACCATCCCATGTGGAATCTGTGAGTGTCCTCTTAAGTAGC GTGGGCTAGCCAATCTGCCGTTCATGGTGTATTGTAAACTCCGAATTCCATATGTAATAGGATGCAAGTCTAAGCGTTTCATGTGGACAT AAATGTATCTAAATAAAACTTTCCCTAGCACTGTGGCTGACCTCACCCTTACTTTTATACTTTAGTATGAAACTGATGAGAACTTTGGTA GTGAGTATTTTTTTTATATATATACATATATATGTACTATCTATATATATATCTCAAGCATCTTTCAGGTCTTTGTGTGTGGCTTTCTTA AAGCCCTGTTGTAAAAAATTACTATGTGGATGGCAGTCTCTCACATCACAGATGTGGAAAGTATAATTTTATATTTGTATTTTCAAATAA ATAAGTTTGTGAAAGGTTTCCATCCTCTACTGTGGTCCAGAAATCAATGTGTTTGTCTGACAAAAAAAAAAATAAAATAAAATAAACTGT >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000322684_chr17_55693331_+_2618nt CTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAGAGTAATATAGG ATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGTTAAATCCAAGG CTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAAT TGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGG AGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGA AGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCC AGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGA AATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGT ACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGA AAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACA ACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTG CTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGA TGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAG AGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTT AGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGT CATGTTCCCACCTGGGACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCC CAACTTCGTGGCGACCTATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGACTATTTGCCGGTTTCACAAGA CATAATTTTTATCAACTAGCTCTTAAGAGAGGCATAGCAAAGTGGGGGTTGCTACCATTTCTAGAGAGAGAGGACACAGTCCCGGCCTGG GCTGCCCCCGCTCCAGTCAATGCTCACTGAAAGTCTGTCTTAGCTGCCTGTTTGAATGACTGTTCTTTTTCTCATTTTTAATTCTTGGAC TCATGTCCTCATTGCTTCACTCAATTAAAAAAAAATTATTCTCCAGTCCCCTCCCACTTTGCTTCTTGTATGCATTGTGACCGACCCCAC TTCCTCAGAATGTAACGGGGCCAGAGGGAAACTTCTCACAAACTTCGTAGAGCCTCCTCAGGGGAAGCTAGGAAGAAGACATCAAATGTT TTTAAGTCATGACCAAACAGGCTTGTTGGGGACATATCATGGGGTGAGCTTTGAAGTGCTGGTGGTCCAGAGGGGTTGCAGATACGTGAC TTGGAGCACCCGTGTCTTACGATGGACAGTGATAAAGGTGAACACACAGAGACAGACTATTCTCTAAGAATGTGAGAAACCTGATCTGGA AGAGGAGCTATATAAACACTATCTGACTATCTTTGTCTTTTGGGGCCAGTGGCTGTTGGCATAATCACAAGCCTGTCTGTCTTCGAGAAG GGACAGTGGAGTCATCCAGGTGCTGCCACATGACAGGCACGGTGGGCACCGATCCACAGTGGGCCCCGCCTTCCCCAGCTCGCCTCCCTG CCTGTGCTGGCCTGGCCTTGCCTGCTGGCACCATTGGAGTAGGAGGGGGTGGAACACAGGGGGCCCATCCTGATCAGGCCCCATCTCAAG GTTGGCACTCCTGCCCATCACCCTTAGAAGGATCTTTTCCCATGGCTTGACTTCCTTCATTTCCCTAACTGAAATACACCCACTCTCTTG GAATAATGACGTACCACTCAGTTGGACCCTCAAGAGTCACTGCTTTGTCTGTGCTGGTAGTTTGTGAGAAGTGACCCGCACGCTTCCATT TGATGCATTTGATGTGAGTGAATCCATACATTTGAATGTCATTGTCCTTGAGACCCTACATGTGCAGTTTGGCTCATCTCATTAAAGATG >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000442934_chr17_55693331_+_2548nt CTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAGAGTAATATAGG ATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGTTAAATCCAAGG CTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAAT TGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGG AGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGA AGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCC AGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGA AATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGT ACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGA AAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACA ACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTG CTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGA TGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAG AGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTT AGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGT CATGTTCCCACCTGGGACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCC CAACTTCGTGGCGACCTATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGGCTTCCCAGCAGCGGCTTATGG ACCAGTGGCAGCAGCGGCGGTGGCGGCAGCAAGAGGATCAGGCTCCAACCCGGCGCGGCCCGGAGGCTTCCCGGGGGCCAACAGCCCAGG ACCTGTCGCCGATCTCTACGGCCCTGCCAGCCAGGACTCCGGAGTGGGGAATTACATAAGTGCGGCCAGCCCACAGCCGGGCTCGGGCTT CGGCCACGGCATAGCTGGACCTTTGATTGCAACGGCCTTTACAAATGGATACCATTGAGCAGGTGCTTTCGTTGCCATCTCACTCTGAGA GCATACCTGGATGTCCAGGCAAGACTGGGCGAAGTTTCTGAGTGGCCCTTTGTTTAGGTGATGTCCTCAGACCTGGACCCCCACCAGCCT CACTCCCCATCCCAACCAGAGATGGCTCACTTCGGATCGAGGGTTGACTACATCTCATCATCTCACGAATCTGCTGTAATATAAGACAAC AGCTTTTAAATGTGTATATAACCCATGATTTCGGTTTTGTTTTGTTTTGTTTTTCTTGATGGTTTCCCTCTCCCTCCCTCTCTTCCCATT CTCCTTTTAAATCTCTTTGAATCACATTTGGTAGTGATTTTGACTTAGTCCAGTAGTCACATAGCTTTAATATCTAGTTCAAAGCTAACC ATAGTATAATTGTTATATTAAGGAGTTATTTTTTCTTAAAACATTTTTTTTTGCTTGTTTTGGTTCTGTTCTCACTTTTAAAGGATGCTG AGATGGTAATATGACTCTCCATATTTTGGTACCAATTCTGAGACTGTATGAATTTTCAGGTGGAACTTTAGCACACACTGAAGCAAAGTT GTGAAGTGCAGGGCGGGAGGTGGGCGTGAGCTTTCTATTTTGCGTTGTAGAAGAAGTGAGATGTAGTAAGCTAATTAACAGACTTTCTAG CAGTTCTTTTTGTGATGTCTCTTTGTTAATCTGAGTCTATCTATTTTCGGCAATAAGGTAAGGACGACAGTGTTTTGAGTGTCCTCCTTT >In-frame_STXBP4_ENST00000434978_chr17_53150437_+_MSI2_ENST00000579180_chr17_55693331_+_2623nt CTTGCAGTCGGGCTACGGAGGCCGGGTTGCCAGATTACGGGAAAGCCATTTAAGAAGTTCCTGGAATAATATTAGTCAGAGTAATATAGG ATCTGCAGGAAGTGTCTCAAGATAGTTGGAAAAGAAGAATTTCTAGACTCTTCATCAAGATCTTCATTTATACAGCTGTTAAATCCAAGG CTACTTTGGTGAAAGCATGAATAAAAATACATCTACTGTAGTATCACCCAGTCTACTTGAAAAGGATCCTGCCTTTCAGATGATTACAAT TGCCAAGGAAACAGGCCTTGGCCTGAAGGTACTAGGAGGAATTAACCGGAATGAAGGCCCATTGGTATATATTCAGGAAATTATTCCTGG AGGAGACTGTTATAAGGATGGTCGTTTGAAGCCAGGAGATCAACTTGTCTCAGTCAACAAGGAATCTATGATTGGTGTATCATTTGAAGA AGCAAAAAGCATAATTACCGGAGCCAAGTTGAGGTTAGAATCTGCTTGGGAGATAGCATTCATAAGACAAAAATCCGACAACATTCAGCC AGAAAATCTGTCATGTACATCACTTATAGAAGCTTCAGGAGAATATGGACCTCAAGCCTCAACATTAAGTCTTTTTTCTTCTCCTCCTGA AATACTAATCCCAAAGACCTCATCCACTCCCAAAACAAATAATGACATTTTATCTTCTTGTGAGATAAAAACTGGATACAACAAAACAGT ACAGATTCCAATTACTTCAGAAAACAGTACTGTGGGTTTGTCTAATACAGATGTTGCTTCTGCCTGGACTGAAAATTATGGGCTACAAGA AAAGATCTCCCTAAATCCCTCTGTTCGCTTTAAGGCAGAGAAACTGGAAATGGCTCTAAATTATCTTGGTATTCAGCCCACAAAGGAACA ACACCAAGCCCTGAGACAGCAAGTACAAGCAGACTCAAAAGGGACAGTGTCTTTTGGAGATTTTGTCCAGGTTGCCAGAAACTTGTTTTG CTTGCAGTTGGATGAAGTAAATGTTGGTGCACATGAAATTTCCAATATATTAGATTCACAGCTTCTTCCTTGTGATTCTTCAGAAGCAGA TGAAATGGAAAGGCTCAAGTGTGAAAGAGATGATGCCTTGAAAGAAGTAAATACACTTAAGGAAGCCAAAGCTGTAGTTGAAGAAACAAG AGCCCTGCGTAGTCGGATTCATCTTGCTGAAGCTGCTCAGAGACAGGCACATGGAATGGAAATGGACTATGAAGAAGTGATCCGTCTGTT AGAGGCCAAGATTACAGAGCTAAAGGCTCAGCTTGCTGATTATTCTGACCAAAATAAAGTAGAATGTAAGAAAGCTCAGCCGAAAGAAGT CATGTTCCCACCTGGGACAAGAGGCCGGGCCCGGGGACTGCCTTACACCATGGACGCGTTCATGCTTGGCATGGGGATGCTGGGATATCC CAACTTCGTGGCGACCTATGGCCGTGGCTACCCCGGATTTGCTCCAAGCTATGGCTATCAGTTCCCAGACTATTTGCCGGTTTCACAAGA CATAATTTTTATCAACTAGCTCTTAAGAGAGGCATAGCAAAGTGGGGGTTGCTACCATTTCTAGAGAGAGAGGACACAGTCCCGGCCTGG GCTGCCCCCGCTCCAGTCAATGCTCACTGAAAGTCTGTCTTAGCTGCCTGTTTGAATGACTGTTCTTTTTCTCATTTTTAATTCTTGGAC TCATGTCCTCATTGCTTCACTCAATTAAAAAAAAATTATTCTCCAGTCCCCTCCCACTTTGCTTCTTGTATGCATTGTGACCGACCCCAC TTCCTCAGAATGTAACGGGGCCAGAGGGAAACTTCTCACAAACTTCGTAGAGCCTCCTCAGGGGAAGCTAGGAAGAAGACATCAAATGTT TTTAAGTCATGACCAAACAGGCTTGTTGGGGACATATCATGGGGTGAGCTTTGAAGTGCTGGTGGTCCAGAGGGGTTGCAGATACGTGAC TTGGAGCACCCGTGTCTTACGATGGACAGTGATAAAGGTGAACACACAGAGACAGACTATTCTCTAAGAATGTGAGAAACCTGATCTGGA AGAGGAGCTATATAAACACTATCTGACTATCTTTGTCTTTTGGGGCCAGTGGCTGTTGGCATAATCACAAGCCTGTCTGTCTTCGAGAAG GGACAGTGGAGTCATCCAGGTGCTGCCACATGACAGGCACGGTGGGCACCGATCCACAGTGGGCCCCGCCTTCCCCAGCTCGCCTCCCTG CCTGTGCTGGCCTGGCCTTGCCTGCTGGCACCATTGGAGTAGGAGGGGGTGGAACACAGGGGGCCCATCCTGATCAGGCCCCATCTCAAG GTTGGCACTCCTGCCCATCACCCTTAGAAGGATCTTTTCCCATGGCTTGACTTCCTTCATTTCCCTAACTGAAATACACCCACTCTCTTG GAATAATGACGTACCACTCAGTTGGACCCTCAAGAGTCACTGCTTTGTCTGTGCTGGTAGTTTGTGAGAAGTGACCCGCACGCTTCCATT TGATGCATTTGATGTGAGTGAATCCATACATTTGAATGTCATTGTCCTTGAGACCCTACATGTGCAGTTTGGCTCATCTCATTAAAGATG |
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FusionGenePPI for STXBP4_MSI2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| STXBP4 | ATN1, LATS2, KLHL42, PRRG4, TMEM171, C20orf195, SUSD6, MBIP, FAM189A2, VPS28, LDLRAD4, TP53, OFD1, CNTROB, CEP128, PTPN13, ERP44, PTPN14, WDTC1, CDR2, ARRDC3, RGS2, CCDC120, PLK1, PMF1, MPP5, PTPN21 | MSI2 | GRB2, H2AFX, CUL3, VCAM1, SOX2, TARDBP, RPA3, RPA2, RPA1, HNRNPH2, MEOX2, SUZ12, RNF2, BMI1, MRPL4, ICK, ANXA13, TIMM10B, RBFOX2, FKBP1A, CRIP1, CTSB, EIF3G, HNRNPA1, PABPC1, PABPC4, PIN1, STIP1, UFM1, WDR1, RAB7A, UBE2L3, NTRK1, CDK1, KIF21A, RHOBTB2, MDM2, TP53, ANKRD40, LOXL3, G3BP1, RNF157 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for STXBP4_MSI2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for STXBP4_MSI2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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