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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 36609

FusionGeneSummary for STRN_SULT6B1

check button Fusion gene summary
Fusion gene informationFusion gene name: STRN_SULT6B1
Fusion gene ID: 36609
HgeneTgene
Gene symbol

STRN

SULT6B1

Gene ID

6801

391365

Gene namestriatinsulfotransferase family 6B member 1
SynonymsPPP2R6A|SG2NA|STRN1-
Cytomap

2p22.2

2p22.2

Type of geneprotein-codingprotein-coding
Descriptionstriatinprotein phosphatase 2 regulatory subunit B'''alphastriatin, calmodulin binding proteinsulfotransferase 6B1ST6B1sulfotransferase SULT6B1sulfotransferase family, cytosolic, 6B, member 1thyroxine sulfotransferase
Modification date2018052320180403
UniProtAcc

O43815

Q6IMI4

Ensembl transtripts involved in fusion geneENST00000263918, ENST00000379213, 
ENST00000260637, ENST00000379149, 
ENST00000535679, ENST00000407963, 
Fusion gene scores* DoF score5 X 6 X 7=2101 X 1 X 1=1
# samples 81
** MAII scorelog2(8/210*10)=-1.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(1/1*10)=3.32192809488736
Context

PubMed: STRN [Title/Abstract] AND SULT6B1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVLIHCTCGA-NI-A4U2-01ASTRNchr2

37126666

-SULT6B1chr2

37415690

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000263918ENST00000260637STRNchr2

37126666

-SULT6B1chr2

37415690

-
In-frameENST00000263918ENST00000379149STRNchr2

37126666

-SULT6B1chr2

37415690

-
In-frameENST00000263918ENST00000535679STRNchr2

37126666

-SULT6B1chr2

37415690

-
5CDS-5UTRENST00000263918ENST00000407963STRNchr2

37126666

-SULT6B1chr2

37415690

-
In-frameENST00000379213ENST00000260637STRNchr2

37126666

-SULT6B1chr2

37415690

-
In-frameENST00000379213ENST00000379149STRNchr2

37126666

-SULT6B1chr2

37415690

-
In-frameENST00000379213ENST00000535679STRNchr2

37126666

-SULT6B1chr2

37415690

-
5CDS-5UTRENST00000379213ENST00000407963STRNchr2

37126666

-SULT6B1chr2

37415690

-

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FusionProtFeatures for STRN_SULT6B1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
STRN

O43815

SULT6B1

Q6IMI4

Calmodulin-binding protein which may function asscaffolding or signaling protein and may play a role in dendriticCa(2+) signaling. Sulfotransferase that utilizes 3'-phospho-5'-adenylylsulfate (PAPS) as sulfonate donor to catalyze the sulfateconjugation of thyroxine. Involved in the metabolism of thyroxine(By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTRNchr2:37126666chr2:37415690ENST00000263918-61853_120265781Coiled coilOntology_term=ECO:0000255
HgeneSTRNchr2:37126666chr2:37415690ENST00000379213-71853_120253732Coiled coilOntology_term=ECO:0000255
HgeneSTRNchr2:37126666chr2:37415690ENST00000263918-618149_166265781RegionCalmodulin-binding
HgeneSTRNchr2:37126666chr2:37415690ENST00000263918-61855_63265781RegionCaveolin-binding
HgeneSTRNchr2:37126666chr2:37415690ENST00000379213-718149_166253732RegionCalmodulin-binding
HgeneSTRNchr2:37126666chr2:37415690ENST00000379213-71855_63253732RegionCaveolin-binding
TgeneSULT6B1chr2:37126666chr2:37415690ENST00000260637--17237_24228266Nucleotide bindingPAPS
TgeneSULT6B1chr2:37126666chr2:37415690ENST00000260637--17259_26128266Nucleotide bindingPAPS
TgeneSULT6B1chr2:37126666chr2:37415690ENST00000260637--1765_7028266Nucleotide bindingPAPS
TgeneSULT6B1chr2:37126666chr2:37415690ENST00000379149-04237_2420200Nucleotide bindingPAPS
TgeneSULT6B1chr2:37126666chr2:37415690ENST00000379149-04259_2610200Nucleotide bindingPAPS
TgeneSULT6B1chr2:37126666chr2:37415690ENST00000379149-0465_700200Nucleotide bindingPAPS
TgeneSULT6B1chr2:37126666chr2:37415690ENST00000407963-08237_242-7266Nucleotide bindingPAPS
TgeneSULT6B1chr2:37126666chr2:37415690ENST00000407963-08259_261-7266Nucleotide bindingPAPS
TgeneSULT6B1chr2:37126666chr2:37415690ENST00000407963-0865_70-7266Nucleotide bindingPAPS
TgeneSULT6B1chr2:37126666chr2:37415690ENST00000535679-07237_2420304Nucleotide bindingPAPS
TgeneSULT6B1chr2:37126666chr2:37415690ENST00000535679-07259_2610304Nucleotide bindingPAPS
TgeneSULT6B1chr2:37126666chr2:37415690ENST00000535679-0765_700304Nucleotide bindingPAPS

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSTRNchr2:37126666chr2:37415690ENST00000263918-618461_500265781RepeatNote=WD 1
HgeneSTRNchr2:37126666chr2:37415690ENST00000263918-618514_553265781RepeatNote=WD 2
HgeneSTRNchr2:37126666chr2:37415690ENST00000263918-618567_606265781RepeatNote=WD 3
HgeneSTRNchr2:37126666chr2:37415690ENST00000263918-618662_701265781RepeatNote=WD 4
HgeneSTRNchr2:37126666chr2:37415690ENST00000263918-618704_743265781RepeatNote=WD 5
HgeneSTRNchr2:37126666chr2:37415690ENST00000263918-618750_779265781RepeatNote=WD 6
HgeneSTRNchr2:37126666chr2:37415690ENST00000379213-718461_500253732RepeatNote=WD 1
HgeneSTRNchr2:37126666chr2:37415690ENST00000379213-718514_553253732RepeatNote=WD 2
HgeneSTRNchr2:37126666chr2:37415690ENST00000379213-718567_606253732RepeatNote=WD 3
HgeneSTRNchr2:37126666chr2:37415690ENST00000379213-718662_701253732RepeatNote=WD 4
HgeneSTRNchr2:37126666chr2:37415690ENST00000379213-718704_743253732RepeatNote=WD 5
HgeneSTRNchr2:37126666chr2:37415690ENST00000379213-718750_779253732RepeatNote=WD 6


Top

FusionGeneSequence for STRN_SULT6B1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_STRN_ENST00000263918_chr2_37126666_-_SULT6B1_ENST00000260637_chr2_37415690_-_265aa
MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKG
QENLKKDLVRRIKMLETALKQERAKYHKLKYGTELNQGDMKPPSTDSDEGNETEVQPQQNSQLMWKQGRQLLRQTLQEVGTTDTILDVKS

>In-frame_STRN_ENST00000263918_chr2_37126666_-_SULT6B1_ENST00000379149_chr2_37415690_-_265aa
MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKG
QENLKKDLVRRIKMLETALKQERAKYHKLKYGTELNQGDMKPPSTDSDEGNETEVQPQQNSQLMWKQGRQLLRQTLQEVGTTDTILDVKS

>In-frame_STRN_ENST00000263918_chr2_37126666_-_SULT6B1_ENST00000535679_chr2_37415690_-_265aa
MDEQAGPGVFFSNNHPGAGGAKGLGPLAEAAAAGDGAAAAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKG
QENLKKDLVRRIKMLETALKQERAKYHKLKYGTELNQGDMKPPSTDSDEGNETEVQPQQNSQLMWKQGRQLLRQTLQEVGTTDTILDVKS

>In-frame_STRN_ENST00000379213_chr2_37126666_-_SULT6B1_ENST00000260637_chr2_37415690_-_253aa
MDEQAGPGVFFSNNHPGAGGAKGLGPLAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRI
KMLETALKQERAKYHKLKYGTELNQGDMKPPSTDSDEGNETEVQPQQNSQLMWKQGRQLLRQTLQEVGTTDTILDVKSKRVRALLGFSSD

>In-frame_STRN_ENST00000379213_chr2_37126666_-_SULT6B1_ENST00000379149_chr2_37415690_-_253aa
MDEQAGPGVFFSNNHPGAGGAKGLGPLAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRI
KMLETALKQERAKYHKLKYGTELNQGDMKPPSTDSDEGNETEVQPQQNSQLMWKQGRQLLRQTLQEVGTTDTILDVKSKRVRALLGFSSD

>In-frame_STRN_ENST00000379213_chr2_37126666_-_SULT6B1_ENST00000535679_chr2_37415690_-_253aa
MDEQAGPGVFFSNNHPGAGGAKGLGPLAGAARAQYSLPGILHFLQHEWARFEVERAQWEVERAELQAQIAFLQGERKGQENLKKDLVRRI
KMLETALKQERAKYHKLKYGTELNQGDMKPPSTDSDEGNETEVQPQQNSQLMWKQGRQLLRQTLQEVGTTDTILDVKSKRVRALLGFSSD


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_STRN_ENST00000263918_chr2_37126666_-_SULT6B1_ENST00000260637_chr2_37415690_-_795nt
ATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTGGCGGAGGCT
GCCGCGGCCGGCGACGGGGCGGCTGCGGCGGGGGCGGCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAGCACGAGTGG
GCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTGGAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAAAGGAAGGGC
CAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATCAAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCACAAGTTGAAA
TACGGGACAGAATTGAATCAGGGAGATATGAAGCCTCCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCACAACAAAAC
AGCCAGTTAATGTGGAAACAAGGTCGACAACTACTCAGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGATGTGAAATCT
AAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGATGTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAATGGCACAGAG
GCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCTGAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTTGAAAGTGCA

>In-frame_STRN_ENST00000263918_chr2_37126666_-_SULT6B1_ENST00000379149_chr2_37415690_-_795nt
ATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTGGCGGAGGCT
GCCGCGGCCGGCGACGGGGCGGCTGCGGCGGGGGCGGCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAGCACGAGTGG
GCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTGGAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAAAGGAAGGGC
CAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATCAAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCACAAGTTGAAA
TACGGGACAGAATTGAATCAGGGAGATATGAAGCCTCCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCACAACAAAAC
AGCCAGTTAATGTGGAAACAAGGTCGACAACTACTCAGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGATGTGAAATCT
AAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGATGTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAATGGCACAGAG
GCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCTGAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTTGAAAGTGCA

>In-frame_STRN_ENST00000263918_chr2_37126666_-_SULT6B1_ENST00000535679_chr2_37415690_-_795nt
ATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTGGCGGAGGCT
GCCGCGGCCGGCGACGGGGCGGCTGCGGCGGGGGCGGCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAGCACGAGTGG
GCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTGGAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAAAGGAAGGGC
CAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATCAAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCACAAGTTGAAA
TACGGGACAGAATTGAATCAGGGAGATATGAAGCCTCCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCACAACAAAAC
AGCCAGTTAATGTGGAAACAAGGTCGACAACTACTCAGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGATGTGAAATCT
AAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGATGTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAATGGCACAGAG
GCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCTGAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTTGAAAGTGCA

>In-frame_STRN_ENST00000379213_chr2_37126666_-_SULT6B1_ENST00000260637_chr2_37415690_-_759nt
ATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTGGCGGGGGCG
GCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAGCACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTG
GAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAAAGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATC
AAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCACAAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCT
CCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCACAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTC
AGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGATGTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGAT
GTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAATGGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCT
GAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTTGAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGAT

>In-frame_STRN_ENST00000379213_chr2_37126666_-_SULT6B1_ENST00000379149_chr2_37415690_-_759nt
ATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTGGCGGGGGCG
GCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAGCACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTG
GAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAAAGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATC
AAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCACAAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCT
CCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCACAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTC
AGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGATGTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGAT
GTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAATGGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCT
GAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTTGAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGAT

>In-frame_STRN_ENST00000379213_chr2_37126666_-_SULT6B1_ENST00000535679_chr2_37415690_-_759nt
ATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTGGCGGGGGCG
GCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAGCACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTG
GAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAAAGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATC
AAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCACAAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCT
CCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCACAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTC
AGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGATGTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGAT
GTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAATGGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCT
GAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTTGAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGAT


* Fusion transcript sequences (Full-length transcript).
>In-frame_STRN_ENST00000263918_chr2_37126666_-_SULT6B1_ENST00000260637_chr2_37415690_-_1738nt
GCGGCCGCCATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTG
GCGGAGGCTGCCGCGGCCGGCGACGGGGCGGCTGCGGCGGGGGCGGCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAG
CACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTGGAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAA
AGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATCAAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCAC
AAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCTCCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCA
CAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTCAGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGAT
GTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGATGTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAAT
GGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCTGAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTT
GAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGATGTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAGGGATT
CCTTACCCCATCACCATGTGCACCTCAGAAACTTTCCAAGCGCTGGACACCTTCGAAGCCAGACATGATGACATCGTGCTAGCATCTTAT
CCAAAGTGCGGTTCAAACTGGATTCTCCACATTGTCAGTGAATTAATATATGCTGTTTCTAAAAAAAAGTATAAATATCCAGAATTCCCA
GTTCTTGAATGTGGGGATTCAGAAAAATATCAGAGAATGAAAGGCTTTCCATCACCAAGGATTTTGGCAACTCACCTCCACTATGACAAA
TTACCTGGGTCTATCTTCGAGAATAAAGCCAAGATATTGGTGATATTTCGAAACCCTAAAGATACAGCAGTATCTTTTTTGCATTTCCAC
AACGATGTCCCCGATATTCCAAGCTATGGCTCTTGGGATGAATTCTTCAGACAGTTCATGAAAGGACAAGTTTCTTGGGGAAGGTATTTT
GATTTTGCAATCAATTGGAACAAACATCTTGATGGCGACAATGTTAAGTTCATATTATATGAAGACCTGAAAGAGAATCTGGCTGCTGGA
ATAAAACAGATTGCTGAGTTCTTGGGATTCTTTCTAACTGGGGAGCAAATTCAAACTATCTCAGTCCAGAGCACCTTCCAAGCCATGCGT
GCGAAGTCTCAGGACACACACGGTGCTGTCGGCCCATTCCTTTTCCGCAAAGGTGAAGTTGGTGATTGGAAAAATTTGTTCAGTGAAATT
CAGAACCAGGAAATGGATGAAAAATTCAAAGAGTGCTTAGCAGGCACCTCCCTCGGAGCAAAGTTGAAGTATGAATCATATTGCCAGGGT
TGATTCCAGTCAATTCAGCAGGCCTAGATTTATTTTCCTTAATAATAATTAAGTGTAAATAATTAAATGATAATTCAATCAAATAATCAA

>In-frame_STRN_ENST00000263918_chr2_37126666_-_SULT6B1_ENST00000379149_chr2_37415690_-_1519nt
GCGGCCGCCATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTG
GCGGAGGCTGCCGCGGCCGGCGACGGGGCGGCTGCGGCGGGGGCGGCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAG
CACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTGGAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAA
AGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATCAAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCAC
AAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCTCCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCA
CAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTCAGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGAT
GTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGATGTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAAT
GGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCTGAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTT
GAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGATGTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAATGGCT
GATAAATCCAAATTTATTGAATACATTGACGAAGCTTTAGAAAAATCAAAAGAAACTGCACTCTCTCATTTATTTTTCACCTATCAGGGG
ATTCCTTACCCCATCACCATGTGCACCTCAGAAACTTTCCAAGCGCTGGACACCTTCGAAGCCAGACATGATGACATCGTGCTAGCATCT
TATCCAAAGTGCGGTTCAAACTGGATTCTCCACATTGTCAGTGAATTAATATATGCTGTTTCTAAAAAAAAGTATAAATATCCAGAATTC
CCAGTTCTTGAATGTGGGGATTCAGAAAAATATCAGAATCTGGCTGCTGGAATAAAACAGATTGCTGAGTTCTTGGGATTCTTTCTAACT
GGGGAGCAAATTCAAACTATCTCAGTCCAGAGCACCTTCCAAGCCATGCGTGCGAAGTCTCAGGACACACACGGTGCTGTCGGCCCATTC
CTTTTCCGCAAAGGTGAAGTTGGTGATTGGAAAAATTTGTTCAGTGAAATTCAGAACCAGGAAATGGATGAAAAATTCAAAGAGTGCTTA
GCAGGCACCTCCCTCGGAGCAAAGTTGAAGTATGAATCATATTGCCAGGGTTGATTCCAGTCAATTCAGCAGGCCTAGATTTATTTTCCT

>In-frame_STRN_ENST00000263918_chr2_37126666_-_SULT6B1_ENST00000535679_chr2_37415690_-_1831nt
GCGGCCGCCATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTG
GCGGAGGCTGCCGCGGCCGGCGACGGGGCGGCTGCGGCGGGGGCGGCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAG
CACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTGGAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAA
AGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATCAAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCAC
AAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCTCCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCA
CAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTCAGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGAT
GTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGATGTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAAT
GGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCTGAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTT
GAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGATGTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAATGGCT
GATAAATCCAAATTTATTGAATACATTGACGAAGCTTTAGAAAAATCAAAAGAAACTGCACTCTCTCATTTATTTTTCACCTATCAGGGG
ATTCCTTACCCCATCACCATGTGCACCTCAGAAACTTTCCAAGCGCTGGACACCTTCGAAGCCAGACATGATGACATCGTGCTAGCATCT
TATCCAAAGTGCGGTTCAAACTGGATTCTCCACATTGTCAGTGAATTAATATATGCTGTTTCTAAAAAAAAGTATAAATATCCAGAATTC
CCAGTTCTTGAATGTGGGGATTCAGAAAAATATCAGAGAATGAAAGGCTTTCCATCACCAAGGATTTTGGCAACTCACCTCCACTATGAC
AAATTACCTGGGTCTATCTTCGAGAATAAAGCCAAGATATTGGTGATATTTCGAAACCCTAAAGATACAGCAGTATCTTTTTTGCATTTC
CACAACGATGTCCCCGATATTCCAAGCTATGGCTCTTGGGATGAATTCTTCAGACAGTTCATGAAAGGACAAGTTTCTTGGGGAAGGTAT
TTTGATTTTGCAATCAATTGGAACAAACATCTTGATGGCGACAATGTTAAGTTCATATTATATGAAGACCTGAAAGAGAATCTGGCTGCT
GGAATAAAACAGATTGCTGAGTTCTTGGGATTCTTTCTAACTGGGGAGCAAATTCAAACTATCTCAGTCCAGAGCACCTTCCAAGCCATG
CGTGCGAAGTCTCAGGACACACACGGTGCTGTCGGCCCATTCCTTTTCCGCAAAGGTGAAGTTGGTGATTGGAAAAATTTGTTCAGTGAA
ATTCAGAACCAGGAAATGGATGAAAAATTCAAAGAGTGCTTAGCAGGCACCTCCCTCGGAGCAAAGTTGAAGTATGAATCATATTGCCAG
GGTTGATTCCAGTCAATTCAGCAGGCCTAGATTTATTTTCCTTAATAATAATTAAGTGTAAATAATTAAATGATAATTCAATCAAATAAT

>In-frame_STRN_ENST00000379213_chr2_37126666_-_SULT6B1_ENST00000260637_chr2_37415690_-_1693nt
ATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTGGCGGGGGCG
GCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAGCACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTG
GAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAAAGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATC
AAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCACAAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCT
CCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCACAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTC
AGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGATGTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGAT
GTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAATGGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCT
GAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTTGAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGAT
GTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAGGGATTCCTTACCCCATCACCATGTGCACCTCAGAAACTTTCCAAGCGCTG
GACACCTTCGAAGCCAGACATGATGACATCGTGCTAGCATCTTATCCAAAGTGCGGTTCAAACTGGATTCTCCACATTGTCAGTGAATTA
ATATATGCTGTTTCTAAAAAAAAGTATAAATATCCAGAATTCCCAGTTCTTGAATGTGGGGATTCAGAAAAATATCAGAGAATGAAAGGC
TTTCCATCACCAAGGATTTTGGCAACTCACCTCCACTATGACAAATTACCTGGGTCTATCTTCGAGAATAAAGCCAAGATATTGGTGATA
TTTCGAAACCCTAAAGATACAGCAGTATCTTTTTTGCATTTCCACAACGATGTCCCCGATATTCCAAGCTATGGCTCTTGGGATGAATTC
TTCAGACAGTTCATGAAAGGACAAGTTTCTTGGGGAAGGTATTTTGATTTTGCAATCAATTGGAACAAACATCTTGATGGCGACAATGTT
AAGTTCATATTATATGAAGACCTGAAAGAGAATCTGGCTGCTGGAATAAAACAGATTGCTGAGTTCTTGGGATTCTTTCTAACTGGGGAG
CAAATTCAAACTATCTCAGTCCAGAGCACCTTCCAAGCCATGCGTGCGAAGTCTCAGGACACACACGGTGCTGTCGGCCCATTCCTTTTC
CGCAAAGGTGAAGTTGGTGATTGGAAAAATTTGTTCAGTGAAATTCAGAACCAGGAAATGGATGAAAAATTCAAAGAGTGCTTAGCAGGC
ACCTCCCTCGGAGCAAAGTTGAAGTATGAATCATATTGCCAGGGTTGATTCCAGTCAATTCAGCAGGCCTAGATTTATTTTCCTTAATAA

>In-frame_STRN_ENST00000379213_chr2_37126666_-_SULT6B1_ENST00000379149_chr2_37415690_-_1474nt
ATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTGGCGGGGGCG
GCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAGCACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTG
GAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAAAGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATC
AAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCACAAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCT
CCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCACAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTC
AGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGATGTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGAT
GTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAATGGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCT
GAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTTGAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGAT
GTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAATGGCTGATAAATCCAAATTTATTGAATACATTGACGAAGCTTTAGAAAAA
TCAAAAGAAACTGCACTCTCTCATTTATTTTTCACCTATCAGGGGATTCCTTACCCCATCACCATGTGCACCTCAGAAACTTTCCAAGCG
CTGGACACCTTCGAAGCCAGACATGATGACATCGTGCTAGCATCTTATCCAAAGTGCGGTTCAAACTGGATTCTCCACATTGTCAGTGAA
TTAATATATGCTGTTTCTAAAAAAAAGTATAAATATCCAGAATTCCCAGTTCTTGAATGTGGGGATTCAGAAAAATATCAGAATCTGGCT
GCTGGAATAAAACAGATTGCTGAGTTCTTGGGATTCTTTCTAACTGGGGAGCAAATTCAAACTATCTCAGTCCAGAGCACCTTCCAAGCC
ATGCGTGCGAAGTCTCAGGACACACACGGTGCTGTCGGCCCATTCCTTTTCCGCAAAGGTGAAGTTGGTGATTGGAAAAATTTGTTCAGT
GAAATTCAGAACCAGGAAATGGATGAAAAATTCAAAGAGTGCTTAGCAGGCACCTCCCTCGGAGCAAAGTTGAAGTATGAATCATATTGC
CAGGGTTGATTCCAGTCAATTCAGCAGGCCTAGATTTATTTTCCTTAATAATAATTAAGTGTAAATAATTAAATGATAATTCAATCAAAT

>In-frame_STRN_ENST00000379213_chr2_37126666_-_SULT6B1_ENST00000535679_chr2_37415690_-_1786nt
ATGGACGAGCAGGCGGGTCCCGGCGTCTTCTTCAGCAACAACCACCCGGGCGCCGGCGGTGCCAAGGGGCTCGGGCCTCTGGCGGGGGCG
GCCCGAGCCCAGTACAGTCTCCCGGGGATCCTGCACTTCCTGCAGCACGAGTGGGCCCGCTTCGAGGTGGAGAGAGCCCAGTGGGAGGTG
GAGCGGGCGGAGCTGCAGGCCCAGATTGCCTTCCTGCAGGGAGAAAGGAAGGGCCAAGAAAATTTGAAGAAGGATCTTGTGAGGAGGATC
AAAATGTTGGAGTATGCTCTTAAACAGGAAAGAGCCAAATACCACAAGTTGAAATACGGGACAGAATTGAATCAGGGAGATATGAAGCCT
CCAAGCTATGATTCTGATGAAGGTAATGAAACAGAAGTGCAGCCACAACAAAACAGCCAGTTAATGTGGAAACAAGGTCGACAACTACTC
AGACAGTATCTACAGGAGGTGGGTTATACAGATACTATTCTAGATGTGAAATCTAAACGAGTGCGAGCTTTGTTGGGCTTTTCAAGTGAT
GTCACGGACAGGGAAGATGACAAAAATCAGGACTCAGTTGTAAATGGCACAGAGGCTGAAGTTAAAGAGACAGCAATGATTGCAAAATCT
GAGTTAACAGATTCTGCCTCCGTGCTGGATAATTTCAAATTCCTTGAAAGTGCAGCTGCAGATTTCAGTGATGAAGATGAAGATGATGAT
GTTGATGGAAGAGAGAAAAGCGTCATTGATACTTCAACAATGGCTGATAAATCCAAATTTATTGAATACATTGACGAAGCTTTAGAAAAA
TCAAAAGAAACTGCACTCTCTCATTTATTTTTCACCTATCAGGGGATTCCTTACCCCATCACCATGTGCACCTCAGAAACTTTCCAAGCG
CTGGACACCTTCGAAGCCAGACATGATGACATCGTGCTAGCATCTTATCCAAAGTGCGGTTCAAACTGGATTCTCCACATTGTCAGTGAA
TTAATATATGCTGTTTCTAAAAAAAAGTATAAATATCCAGAATTCCCAGTTCTTGAATGTGGGGATTCAGAAAAATATCAGAGAATGAAA
GGCTTTCCATCACCAAGGATTTTGGCAACTCACCTCCACTATGACAAATTACCTGGGTCTATCTTCGAGAATAAAGCCAAGATATTGGTG
ATATTTCGAAACCCTAAAGATACAGCAGTATCTTTTTTGCATTTCCACAACGATGTCCCCGATATTCCAAGCTATGGCTCTTGGGATGAA
TTCTTCAGACAGTTCATGAAAGGACAAGTTTCTTGGGGAAGGTATTTTGATTTTGCAATCAATTGGAACAAACATCTTGATGGCGACAAT
GTTAAGTTCATATTATATGAAGACCTGAAAGAGAATCTGGCTGCTGGAATAAAACAGATTGCTGAGTTCTTGGGATTCTTTCTAACTGGG
GAGCAAATTCAAACTATCTCAGTCCAGAGCACCTTCCAAGCCATGCGTGCGAAGTCTCAGGACACACACGGTGCTGTCGGCCCATTCCTT
TTCCGCAAAGGTGAAGTTGGTGATTGGAAAAATTTGTTCAGTGAAATTCAGAACCAGGAAATGGATGAAAAATTCAAAGAGTGCTTAGCA
GGCACCTCCCTCGGAGCAAAGTTGAAGTATGAATCATATTGCCAGGGTTGATTCCAGTCAATTCAGCAGGCCTAGATTTATTTTCCTTAA


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FusionGenePPI for STRN_SULT6B1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
STRNSTK24, MCC, CTTNBP2, CTTNBP2NL, STRIP1, MOB4, PDCD10, PPP2CA, PPP2R1A, STK26, SIKE1, STK25, STRN3, PPP2R1B, STRN4, STRIP2, SLMAP, CCT2, CCT8, CCT3, TCP1, CCT5, FGFR1OP2, CCT6A, CCT7, CCT4, CCT6B, TRAF3IP3, PPP2CB, ZRANB1, ELAVL1, LNX1, APC, TJP1, DDX1, DYNC1H1, CPSF6, EIF2S1, SF3B5, BRCA1, ECT2, PAXIP1, STK3, STK4, TFIP11, RINT1, PCOLCE2, LYPD3, NR1H3, PPP2R2C, RASSF3, PGAM5, NTRK1, HSPB1, DYNLL1, MAP4K4, EEF1E1, BAG2, SLC43A3, AHNAK, PRDM14, TNFRSF1A, NHSL2, PSMC5, PLP1, ZNF550, SNX24, LRRCC1, ZNF331, PRPF19, SPINK2, EXOC1, PKN3, NCKAP5L, TFPT, CCHCR1, YEATS4, TUFT1, RABGAP1L, GOLGA5SULT6B1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for STRN_SULT6B1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for STRN_SULT6B1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource