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Fusion gene ID: 36571 |
FusionGeneSummary for STON2_RPGRIP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: STON2_RPGRIP1 | Fusion gene ID: 36571 | Hgene | Tgene | Gene symbol | STON2 | RPGRIP1 | Gene ID | 85439 | 57096 |
| Gene name | stonin 2 | RPGR interacting protein 1 | |
| Synonyms | STN2|STNB|STNB2 | CORD13|LCA6|RGI1|RGRIP|RPGRIP|RPGRIP1d | |
| Cytomap | 14q31.1 | 14q11.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | stonin-2homolog of stoned Bstoned B homolog 2 | X-linked retinitis pigmentosa GTPase regulator-interacting protein 1retinitis pigmentosa GTPase regulator interacting protein 1 | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q8WXE9 | Q96KN7 | |
| Ensembl transtripts involved in fusion gene | ENST00000555447, ENST00000267540, ENST00000556280, | ENST00000557771, ENST00000556336, ENST00000400017, ENST00000206660, ENST00000382933, ENST00000553500, ENST00000307974, | |
| Fusion gene scores | * DoF score | 4 X 3 X 4=48 | 1 X 1 X 1=1 |
| # samples | 4 | 1 | |
| ** MAII score | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: STON2 [Title/Abstract] AND RPGRIP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | UCEC | TCGA-5B-A90C-01A | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000555447 | ENST00000557771 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| Frame-shift | ENST00000555447 | ENST00000556336 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| 5CDS-intron | ENST00000555447 | ENST00000400017 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| 5CDS-intron | ENST00000555447 | ENST00000206660 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| 5CDS-intron | ENST00000555447 | ENST00000382933 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| 5CDS-intron | ENST00000555447 | ENST00000553500 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| 5CDS-intron | ENST00000555447 | ENST00000307974 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| In-frame | ENST00000267540 | ENST00000557771 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| In-frame | ENST00000267540 | ENST00000556336 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| 5CDS-intron | ENST00000267540 | ENST00000400017 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| 5CDS-intron | ENST00000267540 | ENST00000206660 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| 5CDS-intron | ENST00000267540 | ENST00000382933 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| 5CDS-intron | ENST00000267540 | ENST00000553500 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| 5CDS-intron | ENST00000267540 | ENST00000307974 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| intron-3CDS | ENST00000556280 | ENST00000557771 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| intron-3CDS | ENST00000556280 | ENST00000556336 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| intron-intron | ENST00000556280 | ENST00000400017 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| intron-intron | ENST00000556280 | ENST00000206660 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| intron-intron | ENST00000556280 | ENST00000382933 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| intron-intron | ENST00000556280 | ENST00000553500 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
| intron-intron | ENST00000556280 | ENST00000307974 | STON2 | chr14 | 81837332 | - | RPGRIP1 | chr14 | 21756098 | + |
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FusionProtFeatures for STON2_RPGRIP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| STON2 | RPGRIP1 |
| Adapter protein involved in endocytic machinery.Involved in the synaptic vesicle recycling. May facilitateclathrin-coated vesicle uncoating. {ECO:0000269|PubMed:11381094,ECO:0000269|PubMed:11454741, ECO:0000269|PubMed:21102408}. | May function as scaffolding protein. Required for normallocation of RPGR at the connecting cilium of photoreceptor cells.Required for normal disk morphogenesis and disk organization inthe outer segment of photoreceptor cells and for survival ofphotoreceptor cells. {ECO:0000250|UniProtKB:Q9EPQ2,ECO:0000305|PubMed:10958648}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for STON2_RPGRIP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_STON2_ENST00000267540_chr14_81837332_-_RPGRIP1_ENST00000557771_chr14_21756098_+_1452aa MTTLDHVIATHQSEWVSFNEEPPFPAHSQGGTEEHLPGLSSSPDQSESSSGENHVVDGGSQDHSHSEQDDSSEKMGLISEAASPPGSPEQ PPPDLASAISNWVQFEDDTPWASTSPPHQETAETALPLTMPCWTCPSFDSLGRCPLTSESSWTTHSEDTSSPSFGCSYTDLQLINAEEQT SGQASGADSTVSSGISYSLGTEIMSHLVDPTSGDLPVRDIDAIPLVLPASKGKNMKTQPPLSRMNREELEDSFFRLREDHMLVKELSWKQ QDEIKRLRTTLLRLTAAGRDLRVAEEAAPLSETARRGQKAGWRQRLSMHQRPQMHRLQGHFHCVGPASPRRAQPRVQVGHRQLHTAGAPV PEKPKRGPRDRLSYTAPPSFKEHATNENRGEVASKPSELAHIMASNTMQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKV ELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERV EDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQ EVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMM TKADNDNRDHKEKLERLTRLLDLKNNRIKQLEEQLKDVAYGTRPLSLCLETLPAHGDEDKVDISLLHQGENLFELHIHQAFLTSAALAQA GDTQPTTFCTYSFYDFETHCTPLSVGPQPLYDFTSQYVMETDSLFLHYLQEASARLDIHQAMASEHSTLAAGWICFDRVLETVEKVHGLA TLIGAGGEEFGVLEYWMRLRFPIKPSLQACNKRKKAQVYLSTDVLGGRKAQEEEFRSESWEPQNELWIEITKCCGLRSRWLGTQPSPYAV YRFFTFSDHDTAIIPASNNPYFRDQARFPVLVTSDLDHYLRREALSIHVFDDEDLEPGSYLGRARVPLLPLAKNESIKGDFNLTDPAEKP NGSIQVQLDWKFPYIPPESFLKPEAQTKGKDTKDSSKISSEEEKASFPSQDQMASPEVPIEAGQYRSKRKPPHGGERKEKEHQVVSYSRR KHGKRIGVQGKNRMEYLSLNILNGNTPEQVNYTEWKFSETNSFIGDGFKNQHEEEEMTLSHSALKQKEPLHPVNDKESSEQGSEVSEAQT TDSDDVIVPPMSQKYPKADSEKMCIEIVSLAFYPEAEVMSDENIKQVYVEYKFYDLPLSETETPVSLRKPRAGEEIHFHFSKVIDLDPQE QQGRRRFLFDMLNGQDPDQGHLKFTVVSDPLDEEKKECEEVGYAYLQLWQILESGRDILEQELDIVSPEDLATPIGRLKVSLQAAAVLHA >In-frame_STON2_ENST00000267540_chr14_81837332_-_RPGRIP1_ENST00000556336_chr14_21756098_+_1147aa MTTLDHVIATHQSEWVSFNEEPPFPAHSQGGTEEHLPGLSSSPDQSESSSGENHVVDGGSQDHSHSEQDDSSEKMGLISEAASPPGSPEQ PPPDLASAISNWVQFEDDTPWASTSPPHQETAETALPLTMPCWTCPSFDSLGRCPLTSESSWTTHSEDTSSPSFGCSYTDLQLINAEEQT SGQASGADSTVSSGISYSLGTEIMSHLVDPTSGDLPVRDIDAIPLVLPASKGKNMKTQPPLSRMNREELEDSFFRLREDHMLVKELSWKQ QDEIKRLRTTLLRLTAAGRDLRVAEEAAPLSETARRGQKAGWRQRLSMHQRPQMHRLQGHFHCVGPASPRRAQPRVQVGHRQLHTAGAPV PEKPKRGPRDRLSYTAPPSFKEHATNENRGEVASKPSELAHIMASNTMQVEEPPKSPEKMWPKDENFEQRSSLECAQKAAELRASIKEKV ELIRLKKLLHERNASLVMTKAQLTEVQEAYETLLQKNQGILSAAHEALLKQVNELRAELKEESKKAVSLKSQLEDVSILQMTLKEFQERV EDLEKERKLLNDNYDKLLESMLDSSDSSSQPHWSNELIAEQLQQQVSQLQDQLDAELEDKRKVLLELSREKAQNEDLKLEVTNILQKHKQ EVELLQNAATISQPPDRQSEPATHPAVLQENTQIEPSEPKNQEEKKLSQVLNELQVSHAETTLELEKTRDMLILQRKINVCYQEELEAMM TKADNDNRDHKEKLERLTRLLDLKNNRIKQLEGILRSHDLPTSGDFNLTDPAEKPNGSIQVQLDWKFPYIPPESFLKPEAQTKGKDTKDS SKISSEEEKASFPSQDQMASPEVPIEAGQYRSKRKPPHGGERKEKEHQVVSYSRRKHGKRIGVQGKNRMEYLSLNILNGNTPEQVNYTEW KFSETNSFIGDGFKNQHEEEEMTLSHSALKQKEPLHPVNDKESSEQGSEVSEAQTTDSDDVIVPPMSQKYPKADSEKMCIEIVSLAFYPE AEVMSDENIKQVYVEYKFYDLPLSETETPVSLRKPRAGEEIHFHFSKVIDLDPQEQQGRRRFLFDMLNGQDPDQGHLKFTVVSDPLDEEK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_STON2_ENST00000267540_chr14_81837332_-_RPGRIP1_ENST00000557771_chr14_21756098_+_4356nt ATGACGACTTTGGACCATGTGATTGCCACCCACCAGTCAGAATGGGTCTCCTTCAATGAAGAGCCACCCTTTCCTGCCCACTCGCAGGGG GGCACGGAAGAGCACCTCCCAGGACTGTCATCTTCCCCAGACCAGTCCGAGAGCTCCTCCGGGGAGAACCATGTGGTGGATGGAGGCTCT CAAGACCATTCCCACTCGGAGCAGGATGACTCCTCTGAAAAGATGGGCCTCATCTCTGAAGCAGCTTCCCCACCTGGGAGCCCTGAGCAG CCCCCACCTGACCTGGCCTCGGCCATCAGCAACTGGGTTCAGTTTGAAGATGACACACCCTGGGCCAGCACATCTCCACCTCATCAGGAA ACAGCTGAGACAGCCCTACCATTGACCATGCCCTGCTGGACATGCCCTTCCTTTGACTCCCTGGGGAGATGCCCTCTGACTTCTGAGAGC AGCTGGACCACCCATTCTGAAGACACCAGCAGTCCTAGCTTTGGATGTTCGTATACAGATCTGCAGCTCATCAATGCTGAGGAGCAGACG AGTGGCCAGGCTTCTGGGGCTGACTCAACTGTGTCCTCTGGGATCTCTTACAGCTTGGGAACAGAGATCATGTCACATCTGGTGGACCCT ACATCAGGAGACTTGCCAGTTAGAGACATAGATGCTATACCTCTGGTGCTACCAGCCTCAAAAGGTAAGAATATGAAAACTCAACCACCC TTGAGCAGGATGAACCGGGAGGAATTGGAGGACAGTTTCTTTCGACTTCGCGAAGATCACATGTTGGTGAAGGAGCTTTCTTGGAAGCAA CAGGATGAGATCAAAAGGCTGAGGACCACCTTGCTGCGGTTGACCGCTGCTGGCCGGGACCTGCGGGTCGCGGAGGAGGCGGCGCCGCTC TCGGAGACCGCAAGGCGCGGGCAGAAGGCGGGATGGCGGCAGCGCCTCTCCATGCACCAGCGCCCCCAGATGCACCGACTGCAAGGGCAT TTCCACTGCGTCGGCCCTGCCAGCCCCCGCCGCGCCCAGCCTCGCGTCCAAGTGGGACACAGACAGCTCCACACAGCCGGTGCACCGGTG CCGGAGAAACCCAAGAGGGGGCCAAGGGACAGGCTGAGCTACACAGCCCCTCCATCGTTTAAGGAGCATGCGACAAATGAAAACAGAGGT GAAGTAGCCAGTAAACCCAGTGAACTTGCCCACATCATGGCCAGCAATACCATGCAAGTGGAAGAGCCACCCAAGTCTCCTGAGAAAATG TGGCCTAAAGATGAAAATTTTGAACAGAGAAGCTCATTGGAGTGTGCTCAGAAGGCTGCAGAGCTTCGAGCTTCCATTAAAGAGAAGGTA GAGCTGATTCGACTTAAGAAGCTCTTACATGAAAGAAATGCTTCATTGGTTATGACAAAAGCACAATTAACAGAAGTTCAAGAGGCATAC GAAACCTTGCTCCAGAAGAATCAGGGAATCCTGAGTGCAGCCCATGAGGCCCTCCTCAAGCAAGTGAATGAGCTCAGGGCAGAGCTGAAG GAAGAAAGCAAGAAGGCTGTGAGCTTGAAGAGCCAACTGGAAGATGTGTCTATCTTGCAGATGACTCTGAAGGAGTTTCAGGAGAGAGTT GAAGATTTGGAAAAAGAACGAAAATTGCTGAATGACAATTATGACAAACTCTTAGAAAGCATGCTGGACAGCAGTGACAGCTCCAGTCAG CCCCACTGGAGCAACGAGCTCATAGCGGAACAGCTACAGCAGCAAGTCTCTCAGCTGCAGGATCAGCTGGATGCTGAGCTGGAGGACAAG AGAAAAGTTTTACTTGAGCTGTCCAGGGAGAAAGCCCAAAATGAGGATCTGAAGCTTGAAGTCACCAACATACTTCAGAAGCATAAACAG GAAGTAGAGCTCCTCCAAAATGCAGCCACAATTTCCCAACCTCCTGACAGGCAATCTGAACCAGCCACTCACCCAGCTGTATTGCAAGAG AACACTCAGATCGAGCCAAGTGAACCCAAAAACCAAGAAGAAAAGAAACTGTCCCAGGTGCTAAATGAGTTGCAAGTATCACACGCAGAG ACCACATTGGAACTAGAAAAGACCAGGGACATGCTTATTCTGCAGCGCAAAATCAACGTGTGTTATCAGGAGGAACTGGAGGCAATGATG ACAAAAGCTGACAATGATAATAGAGATCACAAAGAAAAGCTGGAGAGGTTGACTCGACTACTAGACCTCAAGAATAACCGTATCAAGCAG CTGGAAGAACAGCTCAAAGATGTTGCTTATGGCACCCGACCGTTGTCGTTATGTTTGGAAACACTGCCAGCCCATGGAGATGAGGATAAA GTGGATATTTCTCTGCTGCATCAGGGTGAGAATCTTTTTGAACTGCACATCCACCAGGCCTTCCTGACATCTGCCGCCCTAGCTCAGGCT GGAGATACCCAACCTACCACTTTCTGCACCTATTCCTTCTATGACTTTGAAACCCACTGTACCCCATTATCTGTGGGGCCACAGCCCCTC TATGACTTCACCTCCCAGTATGTGATGGAGACAGATTCGCTTTTCTTACACTACCTTCAAGAGGCTTCAGCCCGGCTTGACATACACCAG GCCATGGCCAGTGAACACAGCACTCTTGCTGCAGGATGGATTTGCTTTGACAGGGTGCTAGAGACTGTGGAGAAAGTCCATGGCTTGGCC ACACTGATTGGAGCTGGTGGAGAAGAGTTCGGGGTTCTAGAGTACTGGATGAGGCTGCGTTTCCCCATAAAACCCAGCCTACAGGCGTGC AATAAACGAAAGAAAGCCCAGGTCTACCTGTCAACCGATGTGCTTGGAGGCCGGAAGGCCCAGGAAGAGGAGTTCAGATCGGAGTCTTGG GAACCTCAGAACGAGCTGTGGATTGAAATCACCAAGTGCTGTGGCCTCCGGAGTCGATGGCTGGGAACTCAACCCAGTCCATATGCTGTG TACCGCTTCTTCACCTTTTCTGACCATGACACTGCCATCATTCCAGCCAGTAACAACCCCTACTTTAGAGACCAGGCTCGATTCCCAGTG CTTGTGACCTCTGACCTGGACCATTATCTGAGACGGGAGGCCTTGTCTATACATGTTTTTGATGATGAAGACTTAGAGCCTGGCTCGTAT CTTGGCCGAGCCCGAGTGCCTTTACTGCCTCTTGCAAAAAATGAATCTATCAAAGGTGATTTTAACCTCACTGACCCTGCAGAGAAACCC AACGGATCTATTCAAGTGCAACTGGATTGGAAGTTTCCCTACATACCCCCTGAGAGCTTCCTGAAACCAGAAGCTCAGACTAAGGGGAAG GATACCAAGGACAGTTCAAAGATCTCATCTGAAGAGGAAAAGGCTTCATTTCCTTCCCAGGATCAGATGGCATCTCCTGAGGTTCCCATT GAAGCTGGCCAGTATCGATCTAAGAGAAAACCTCCTCATGGGGGAGAAAGAAAGGAGAAGGAGCACCAGGTTGTGAGCTACTCAAGAAGA AAACATGGCAAAAGAATAGGTGTTCAAGGAAAGAATAGAATGGAGTATCTTAGCCTTAACATCTTAAATGGAAATACACCAGAGCAGGTG AATTACACTGAGTGGAAGTTCTCAGAGACTAACAGCTTCATAGGTGATGGCTTTAAAAATCAGCACGAGGAAGAGGAAATGACATTATCC CATTCAGCACTGAAACAGAAGGAACCTCTACATCCTGTAAATGACAAAGAATCCTCTGAACAAGGTTCTGAAGTCAGTGAAGCACAAACT ACCGACAGTGATGATGTCATAGTGCCACCCATGTCTCAGAAATATCCTAAGGCAGATTCAGAGAAGATGTGCATTGAAATTGTCTCCCTG GCCTTCTACCCAGAGGCAGAAGTGATGTCTGATGAGAACATAAAACAGGTGTATGTGGAGTACAAATTCTACGACCTACCCTTGTCGGAG ACAGAGACTCCAGTGTCCCTAAGGAAGCCTAGGGCAGGAGAAGAAATCCACTTTCACTTTAGCAAGGTAATAGACCTGGACCCACAGGAG CAGCAAGGCCGAAGGCGGTTTCTGTTCGACATGCTGAATGGACAAGATCCTGATCAAGGACATTTAAAGTTTACAGTGGTAAGTGATCCT CTGGATGAAGAAAAGAAAGAATGTGAAGAAGTGGGATATGCATATCTTCAACTGTGGCAGATCCTGGAGTCAGGAAGAGATATTCTAGAG CAAGAGCTAGACATTGTTAGCCCTGAAGATCTGGCTACCCCAATAGGAAGGCTGAAGGTTTCCCTTCAAGCAGCTGCTGTCCTCCATGCT >In-frame_STON2_ENST00000267540_chr14_81837332_-_RPGRIP1_ENST00000556336_chr14_21756098_+_3441nt ATGACGACTTTGGACCATGTGATTGCCACCCACCAGTCAGAATGGGTCTCCTTCAATGAAGAGCCACCCTTTCCTGCCCACTCGCAGGGG GGCACGGAAGAGCACCTCCCAGGACTGTCATCTTCCCCAGACCAGTCCGAGAGCTCCTCCGGGGAGAACCATGTGGTGGATGGAGGCTCT CAAGACCATTCCCACTCGGAGCAGGATGACTCCTCTGAAAAGATGGGCCTCATCTCTGAAGCAGCTTCCCCACCTGGGAGCCCTGAGCAG CCCCCACCTGACCTGGCCTCGGCCATCAGCAACTGGGTTCAGTTTGAAGATGACACACCCTGGGCCAGCACATCTCCACCTCATCAGGAA ACAGCTGAGACAGCCCTACCATTGACCATGCCCTGCTGGACATGCCCTTCCTTTGACTCCCTGGGGAGATGCCCTCTGACTTCTGAGAGC AGCTGGACCACCCATTCTGAAGACACCAGCAGTCCTAGCTTTGGATGTTCGTATACAGATCTGCAGCTCATCAATGCTGAGGAGCAGACG AGTGGCCAGGCTTCTGGGGCTGACTCAACTGTGTCCTCTGGGATCTCTTACAGCTTGGGAACAGAGATCATGTCACATCTGGTGGACCCT ACATCAGGAGACTTGCCAGTTAGAGACATAGATGCTATACCTCTGGTGCTACCAGCCTCAAAAGGTAAGAATATGAAAACTCAACCACCC TTGAGCAGGATGAACCGGGAGGAATTGGAGGACAGTTTCTTTCGACTTCGCGAAGATCACATGTTGGTGAAGGAGCTTTCTTGGAAGCAA CAGGATGAGATCAAAAGGCTGAGGACCACCTTGCTGCGGTTGACCGCTGCTGGCCGGGACCTGCGGGTCGCGGAGGAGGCGGCGCCGCTC TCGGAGACCGCAAGGCGCGGGCAGAAGGCGGGATGGCGGCAGCGCCTCTCCATGCACCAGCGCCCCCAGATGCACCGACTGCAAGGGCAT TTCCACTGCGTCGGCCCTGCCAGCCCCCGCCGCGCCCAGCCTCGCGTCCAAGTGGGACACAGACAGCTCCACACAGCCGGTGCACCGGTG CCGGAGAAACCCAAGAGGGGGCCAAGGGACAGGCTGAGCTACACAGCCCCTCCATCGTTTAAGGAGCATGCGACAAATGAAAACAGAGGT GAAGTAGCCAGTAAACCCAGTGAACTTGCCCACATCATGGCCAGCAATACCATGCAAGTGGAAGAGCCACCCAAGTCTCCTGAGAAAATG TGGCCTAAAGATGAAAATTTTGAACAGAGAAGCTCATTGGAGTGTGCTCAGAAGGCTGCAGAGCTTCGAGCTTCCATTAAAGAGAAGGTA GAGCTGATTCGACTTAAGAAGCTCTTACATGAAAGAAATGCTTCATTGGTTATGACAAAAGCACAATTAACAGAAGTTCAAGAGGCATAC GAAACCTTGCTCCAGAAGAATCAGGGAATCCTGAGTGCAGCCCATGAGGCCCTCCTCAAGCAAGTGAATGAGCTCAGGGCAGAGCTGAAG GAAGAAAGCAAGAAGGCTGTGAGCTTGAAGAGCCAACTGGAAGATGTGTCTATCTTGCAGATGACTCTGAAGGAGTTTCAGGAGAGAGTT GAAGATTTGGAAAAAGAACGAAAATTGCTGAATGACAATTATGACAAACTCTTAGAAAGCATGCTGGACAGCAGTGACAGCTCCAGTCAG CCCCACTGGAGCAACGAGCTCATAGCGGAACAGCTACAGCAGCAAGTCTCTCAGCTGCAGGATCAGCTGGATGCTGAGCTGGAGGACAAG AGAAAAGTTTTACTTGAGCTGTCCAGGGAGAAAGCCCAAAATGAGGATCTGAAGCTTGAAGTCACCAACATACTTCAGAAGCATAAACAG GAAGTAGAGCTCCTCCAAAATGCAGCCACAATTTCCCAACCTCCTGACAGGCAATCTGAACCAGCCACTCACCCAGCTGTATTGCAAGAG AACACTCAGATCGAGCCAAGTGAACCCAAAAACCAAGAAGAAAAGAAACTGTCCCAGGTGCTAAATGAGTTGCAAGTATCACACGCAGAG ACCACATTGGAACTAGAAAAGACCAGGGACATGCTTATTCTGCAGCGCAAAATCAACGTGTGTTATCAGGAGGAACTGGAGGCAATGATG ACAAAAGCTGACAATGATAATAGAGATCACAAAGAAAAGCTGGAGAGGTTGACTCGACTACTAGACCTCAAGAATAACCGTATCAAGCAG CTGGAAGGTATTTTAAGAAGCCATGACCTTCCAACATCTGGTGATTTTAACCTCACTGACCCTGCAGAGAAACCCAACGGATCTATTCAA GTGCAACTGGATTGGAAGTTTCCCTACATACCCCCTGAGAGCTTCCTGAAACCAGAAGCTCAGACTAAGGGGAAGGATACCAAGGACAGT TCAAAGATCTCATCTGAAGAGGAAAAGGCTTCATTTCCTTCCCAGGATCAGATGGCATCTCCTGAGGTTCCCATTGAAGCTGGCCAGTAT CGATCTAAGAGAAAACCTCCTCATGGGGGAGAAAGAAAGGAGAAGGAGCACCAGGTTGTGAGCTACTCAAGAAGAAAACATGGCAAAAGA ATAGGTGTTCAAGGAAAGAATAGAATGGAGTATCTTAGCCTTAACATCTTAAATGGAAATACACCAGAGCAGGTGAATTACACTGAGTGG AAGTTCTCAGAGACTAACAGCTTCATAGGTGATGGCTTTAAAAATCAGCACGAGGAAGAGGAAATGACATTATCCCATTCAGCACTGAAA CAGAAGGAACCTCTACATCCTGTAAATGACAAAGAATCCTCTGAACAAGGTTCTGAAGTCAGTGAAGCACAAACTACCGACAGTGATGAT GTCATAGTGCCACCCATGTCTCAGAAATATCCTAAGGCAGATTCAGAGAAGATGTGCATTGAAATTGTCTCCCTGGCCTTCTACCCAGAG GCAGAAGTGATGTCTGATGAGAACATAAAACAGGTGTATGTGGAGTACAAATTCTACGACCTACCCTTGTCGGAGACAGAGACTCCAGTG TCCCTAAGGAAGCCTAGGGCAGGAGAAGAAATCCACTTTCACTTTAGCAAGGTAATAGACCTGGACCCACAGGAGCAGCAAGGCCGAAGG CGGTTTCTGTTCGACATGCTGAATGGACAAGATCCTGATCAAGGACATTTAAAGTTTACAGTGGTAAGTGATCCTCTGGATGAAGAAAAG AAAGAATGTGAAGAAGTGGGATATGCATATCTTCAACTGTGGCAGATCCTGGAGTCAGGAAGAGATATTCTAGAGCAAGAGCTAGACATT GTTAGCCCTGAAGATCTGGCTACCCCAATAGGAAGGCTGAAGGTTTCCCTTCAAGCAGCTGCTGTCCTCCATGCTATTTACAAGGAGATG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_STON2_ENST00000267540_chr14_81837332_-_RPGRIP1_ENST00000557771_chr14_21756098_+_4642nt CAGATTTCTGCCTGGCAGATTAACCAACGGCAAGAGAGGCTGATCTGTCTACATTCTGAGTACTGCCCTTGGCAAGACACCTAGAACAGA CCCTGGACCCAAGTCTACCGTACTACCATACCCCTACTCCAGCCCACCCCAGACAGTATTCTGGGGTTCACCTGAGGTCAGCAGTGTGAA GATGACCAGTGCCTTTTTAGCATGACGACTTTGGACCATGTGATTGCCACCCACCAGTCAGAATGGGTCTCCTTCAATGAAGAGCCACCC TTTCCTGCCCACTCGCAGGGGGGCACGGAAGAGCACCTCCCAGGACTGTCATCTTCCCCAGACCAGTCCGAGAGCTCCTCCGGGGAGAAC CATGTGGTGGATGGAGGCTCTCAAGACCATTCCCACTCGGAGCAGGATGACTCCTCTGAAAAGATGGGCCTCATCTCTGAAGCAGCTTCC CCACCTGGGAGCCCTGAGCAGCCCCCACCTGACCTGGCCTCGGCCATCAGCAACTGGGTTCAGTTTGAAGATGACACACCCTGGGCCAGC ACATCTCCACCTCATCAGGAAACAGCTGAGACAGCCCTACCATTGACCATGCCCTGCTGGACATGCCCTTCCTTTGACTCCCTGGGGAGA TGCCCTCTGACTTCTGAGAGCAGCTGGACCACCCATTCTGAAGACACCAGCAGTCCTAGCTTTGGATGTTCGTATACAGATCTGCAGCTC ATCAATGCTGAGGAGCAGACGAGTGGCCAGGCTTCTGGGGCTGACTCAACTGTGTCCTCTGGGATCTCTTACAGCTTGGGAACAGAGATC ATGTCACATCTGGTGGACCCTACATCAGGAGACTTGCCAGTTAGAGACATAGATGCTATACCTCTGGTGCTACCAGCCTCAAAAGGTAAG AATATGAAAACTCAACCACCCTTGAGCAGGATGAACCGGGAGGAATTGGAGGACAGTTTCTTTCGACTTCGCGAAGATCACATGTTGGTG AAGGAGCTTTCTTGGAAGCAACAGGATGAGATCAAAAGGCTGAGGACCACCTTGCTGCGGTTGACCGCTGCTGGCCGGGACCTGCGGGTC GCGGAGGAGGCGGCGCCGCTCTCGGAGACCGCAAGGCGCGGGCAGAAGGCGGGATGGCGGCAGCGCCTCTCCATGCACCAGCGCCCCCAG ATGCACCGACTGCAAGGGCATTTCCACTGCGTCGGCCCTGCCAGCCCCCGCCGCGCCCAGCCTCGCGTCCAAGTGGGACACAGACAGCTC CACACAGCCGGTGCACCGGTGCCGGAGAAACCCAAGAGGGGGCCAAGGGACAGGCTGAGCTACACAGCCCCTCCATCGTTTAAGGAGCAT GCGACAAATGAAAACAGAGGTGAAGTAGCCAGTAAACCCAGTGAACTTGCCCACATCATGGCCAGCAATACCATGCAAGTGGAAGAGCCA CCCAAGTCTCCTGAGAAAATGTGGCCTAAAGATGAAAATTTTGAACAGAGAAGCTCATTGGAGTGTGCTCAGAAGGCTGCAGAGCTTCGA GCTTCCATTAAAGAGAAGGTAGAGCTGATTCGACTTAAGAAGCTCTTACATGAAAGAAATGCTTCATTGGTTATGACAAAAGCACAATTA ACAGAAGTTCAAGAGGCATACGAAACCTTGCTCCAGAAGAATCAGGGAATCCTGAGTGCAGCCCATGAGGCCCTCCTCAAGCAAGTGAAT GAGCTCAGGGCAGAGCTGAAGGAAGAAAGCAAGAAGGCTGTGAGCTTGAAGAGCCAACTGGAAGATGTGTCTATCTTGCAGATGACTCTG AAGGAGTTTCAGGAGAGAGTTGAAGATTTGGAAAAAGAACGAAAATTGCTGAATGACAATTATGACAAACTCTTAGAAAGCATGCTGGAC AGCAGTGACAGCTCCAGTCAGCCCCACTGGAGCAACGAGCTCATAGCGGAACAGCTACAGCAGCAAGTCTCTCAGCTGCAGGATCAGCTG GATGCTGAGCTGGAGGACAAGAGAAAAGTTTTACTTGAGCTGTCCAGGGAGAAAGCCCAAAATGAGGATCTGAAGCTTGAAGTCACCAAC ATACTTCAGAAGCATAAACAGGAAGTAGAGCTCCTCCAAAATGCAGCCACAATTTCCCAACCTCCTGACAGGCAATCTGAACCAGCCACT CACCCAGCTGTATTGCAAGAGAACACTCAGATCGAGCCAAGTGAACCCAAAAACCAAGAAGAAAAGAAACTGTCCCAGGTGCTAAATGAG TTGCAAGTATCACACGCAGAGACCACATTGGAACTAGAAAAGACCAGGGACATGCTTATTCTGCAGCGCAAAATCAACGTGTGTTATCAG GAGGAACTGGAGGCAATGATGACAAAAGCTGACAATGATAATAGAGATCACAAAGAAAAGCTGGAGAGGTTGACTCGACTACTAGACCTC AAGAATAACCGTATCAAGCAGCTGGAAGAACAGCTCAAAGATGTTGCTTATGGCACCCGACCGTTGTCGTTATGTTTGGAAACACTGCCA GCCCATGGAGATGAGGATAAAGTGGATATTTCTCTGCTGCATCAGGGTGAGAATCTTTTTGAACTGCACATCCACCAGGCCTTCCTGACA TCTGCCGCCCTAGCTCAGGCTGGAGATACCCAACCTACCACTTTCTGCACCTATTCCTTCTATGACTTTGAAACCCACTGTACCCCATTA TCTGTGGGGCCACAGCCCCTCTATGACTTCACCTCCCAGTATGTGATGGAGACAGATTCGCTTTTCTTACACTACCTTCAAGAGGCTTCA GCCCGGCTTGACATACACCAGGCCATGGCCAGTGAACACAGCACTCTTGCTGCAGGATGGATTTGCTTTGACAGGGTGCTAGAGACTGTG GAGAAAGTCCATGGCTTGGCCACACTGATTGGAGCTGGTGGAGAAGAGTTCGGGGTTCTAGAGTACTGGATGAGGCTGCGTTTCCCCATA AAACCCAGCCTACAGGCGTGCAATAAACGAAAGAAAGCCCAGGTCTACCTGTCAACCGATGTGCTTGGAGGCCGGAAGGCCCAGGAAGAG GAGTTCAGATCGGAGTCTTGGGAACCTCAGAACGAGCTGTGGATTGAAATCACCAAGTGCTGTGGCCTCCGGAGTCGATGGCTGGGAACT CAACCCAGTCCATATGCTGTGTACCGCTTCTTCACCTTTTCTGACCATGACACTGCCATCATTCCAGCCAGTAACAACCCCTACTTTAGA GACCAGGCTCGATTCCCAGTGCTTGTGACCTCTGACCTGGACCATTATCTGAGACGGGAGGCCTTGTCTATACATGTTTTTGATGATGAA GACTTAGAGCCTGGCTCGTATCTTGGCCGAGCCCGAGTGCCTTTACTGCCTCTTGCAAAAAATGAATCTATCAAAGGTGATTTTAACCTC ACTGACCCTGCAGAGAAACCCAACGGATCTATTCAAGTGCAACTGGATTGGAAGTTTCCCTACATACCCCCTGAGAGCTTCCTGAAACCA GAAGCTCAGACTAAGGGGAAGGATACCAAGGACAGTTCAAAGATCTCATCTGAAGAGGAAAAGGCTTCATTTCCTTCCCAGGATCAGATG GCATCTCCTGAGGTTCCCATTGAAGCTGGCCAGTATCGATCTAAGAGAAAACCTCCTCATGGGGGAGAAAGAAAGGAGAAGGAGCACCAG GTTGTGAGCTACTCAAGAAGAAAACATGGCAAAAGAATAGGTGTTCAAGGAAAGAATAGAATGGAGTATCTTAGCCTTAACATCTTAAAT GGAAATACACCAGAGCAGGTGAATTACACTGAGTGGAAGTTCTCAGAGACTAACAGCTTCATAGGTGATGGCTTTAAAAATCAGCACGAG GAAGAGGAAATGACATTATCCCATTCAGCACTGAAACAGAAGGAACCTCTACATCCTGTAAATGACAAAGAATCCTCTGAACAAGGTTCT GAAGTCAGTGAAGCACAAACTACCGACAGTGATGATGTCATAGTGCCACCCATGTCTCAGAAATATCCTAAGGCAGATTCAGAGAAGATG TGCATTGAAATTGTCTCCCTGGCCTTCTACCCAGAGGCAGAAGTGATGTCTGATGAGAACATAAAACAGGTGTATGTGGAGTACAAATTC TACGACCTACCCTTGTCGGAGACAGAGACTCCAGTGTCCCTAAGGAAGCCTAGGGCAGGAGAAGAAATCCACTTTCACTTTAGCAAGGTA ATAGACCTGGACCCACAGGAGCAGCAAGGCCGAAGGCGGTTTCTGTTCGACATGCTGAATGGACAAGATCCTGATCAAGGACATTTAAAG TTTACAGTGGTAAGTGATCCTCTGGATGAAGAAAAGAAAGAATGTGAAGAAGTGGGATATGCATATCTTCAACTGTGGCAGATCCTGGAG TCAGGAAGAGATATTCTAGAGCAAGAGCTAGACATTGTTAGCCCTGAAGATCTGGCTACCCCAATAGGAAGGCTGAAGGTTTCCCTTCAA GCAGCTGCTGTCCTCCATGCTATTTACAAGGAGATGACTGAAGATTTGTTTTCATGAAGGAACAAGTGCTATTCCAATCTAAAAGTCTCT >In-frame_STON2_ENST00000267540_chr14_81837332_-_RPGRIP1_ENST00000556336_chr14_21756098_+_3727nt CAGATTTCTGCCTGGCAGATTAACCAACGGCAAGAGAGGCTGATCTGTCTACATTCTGAGTACTGCCCTTGGCAAGACACCTAGAACAGA CCCTGGACCCAAGTCTACCGTACTACCATACCCCTACTCCAGCCCACCCCAGACAGTATTCTGGGGTTCACCTGAGGTCAGCAGTGTGAA GATGACCAGTGCCTTTTTAGCATGACGACTTTGGACCATGTGATTGCCACCCACCAGTCAGAATGGGTCTCCTTCAATGAAGAGCCACCC TTTCCTGCCCACTCGCAGGGGGGCACGGAAGAGCACCTCCCAGGACTGTCATCTTCCCCAGACCAGTCCGAGAGCTCCTCCGGGGAGAAC CATGTGGTGGATGGAGGCTCTCAAGACCATTCCCACTCGGAGCAGGATGACTCCTCTGAAAAGATGGGCCTCATCTCTGAAGCAGCTTCC CCACCTGGGAGCCCTGAGCAGCCCCCACCTGACCTGGCCTCGGCCATCAGCAACTGGGTTCAGTTTGAAGATGACACACCCTGGGCCAGC ACATCTCCACCTCATCAGGAAACAGCTGAGACAGCCCTACCATTGACCATGCCCTGCTGGACATGCCCTTCCTTTGACTCCCTGGGGAGA TGCCCTCTGACTTCTGAGAGCAGCTGGACCACCCATTCTGAAGACACCAGCAGTCCTAGCTTTGGATGTTCGTATACAGATCTGCAGCTC ATCAATGCTGAGGAGCAGACGAGTGGCCAGGCTTCTGGGGCTGACTCAACTGTGTCCTCTGGGATCTCTTACAGCTTGGGAACAGAGATC ATGTCACATCTGGTGGACCCTACATCAGGAGACTTGCCAGTTAGAGACATAGATGCTATACCTCTGGTGCTACCAGCCTCAAAAGGTAAG AATATGAAAACTCAACCACCCTTGAGCAGGATGAACCGGGAGGAATTGGAGGACAGTTTCTTTCGACTTCGCGAAGATCACATGTTGGTG AAGGAGCTTTCTTGGAAGCAACAGGATGAGATCAAAAGGCTGAGGACCACCTTGCTGCGGTTGACCGCTGCTGGCCGGGACCTGCGGGTC GCGGAGGAGGCGGCGCCGCTCTCGGAGACCGCAAGGCGCGGGCAGAAGGCGGGATGGCGGCAGCGCCTCTCCATGCACCAGCGCCCCCAG ATGCACCGACTGCAAGGGCATTTCCACTGCGTCGGCCCTGCCAGCCCCCGCCGCGCCCAGCCTCGCGTCCAAGTGGGACACAGACAGCTC CACACAGCCGGTGCACCGGTGCCGGAGAAACCCAAGAGGGGGCCAAGGGACAGGCTGAGCTACACAGCCCCTCCATCGTTTAAGGAGCAT GCGACAAATGAAAACAGAGGTGAAGTAGCCAGTAAACCCAGTGAACTTGCCCACATCATGGCCAGCAATACCATGCAAGTGGAAGAGCCA CCCAAGTCTCCTGAGAAAATGTGGCCTAAAGATGAAAATTTTGAACAGAGAAGCTCATTGGAGTGTGCTCAGAAGGCTGCAGAGCTTCGA GCTTCCATTAAAGAGAAGGTAGAGCTGATTCGACTTAAGAAGCTCTTACATGAAAGAAATGCTTCATTGGTTATGACAAAAGCACAATTA ACAGAAGTTCAAGAGGCATACGAAACCTTGCTCCAGAAGAATCAGGGAATCCTGAGTGCAGCCCATGAGGCCCTCCTCAAGCAAGTGAAT GAGCTCAGGGCAGAGCTGAAGGAAGAAAGCAAGAAGGCTGTGAGCTTGAAGAGCCAACTGGAAGATGTGTCTATCTTGCAGATGACTCTG AAGGAGTTTCAGGAGAGAGTTGAAGATTTGGAAAAAGAACGAAAATTGCTGAATGACAATTATGACAAACTCTTAGAAAGCATGCTGGAC AGCAGTGACAGCTCCAGTCAGCCCCACTGGAGCAACGAGCTCATAGCGGAACAGCTACAGCAGCAAGTCTCTCAGCTGCAGGATCAGCTG GATGCTGAGCTGGAGGACAAGAGAAAAGTTTTACTTGAGCTGTCCAGGGAGAAAGCCCAAAATGAGGATCTGAAGCTTGAAGTCACCAAC ATACTTCAGAAGCATAAACAGGAAGTAGAGCTCCTCCAAAATGCAGCCACAATTTCCCAACCTCCTGACAGGCAATCTGAACCAGCCACT CACCCAGCTGTATTGCAAGAGAACACTCAGATCGAGCCAAGTGAACCCAAAAACCAAGAAGAAAAGAAACTGTCCCAGGTGCTAAATGAG TTGCAAGTATCACACGCAGAGACCACATTGGAACTAGAAAAGACCAGGGACATGCTTATTCTGCAGCGCAAAATCAACGTGTGTTATCAG GAGGAACTGGAGGCAATGATGACAAAAGCTGACAATGATAATAGAGATCACAAAGAAAAGCTGGAGAGGTTGACTCGACTACTAGACCTC AAGAATAACCGTATCAAGCAGCTGGAAGGTATTTTAAGAAGCCATGACCTTCCAACATCTGGTGATTTTAACCTCACTGACCCTGCAGAG AAACCCAACGGATCTATTCAAGTGCAACTGGATTGGAAGTTTCCCTACATACCCCCTGAGAGCTTCCTGAAACCAGAAGCTCAGACTAAG GGGAAGGATACCAAGGACAGTTCAAAGATCTCATCTGAAGAGGAAAAGGCTTCATTTCCTTCCCAGGATCAGATGGCATCTCCTGAGGTT CCCATTGAAGCTGGCCAGTATCGATCTAAGAGAAAACCTCCTCATGGGGGAGAAAGAAAGGAGAAGGAGCACCAGGTTGTGAGCTACTCA AGAAGAAAACATGGCAAAAGAATAGGTGTTCAAGGAAAGAATAGAATGGAGTATCTTAGCCTTAACATCTTAAATGGAAATACACCAGAG CAGGTGAATTACACTGAGTGGAAGTTCTCAGAGACTAACAGCTTCATAGGTGATGGCTTTAAAAATCAGCACGAGGAAGAGGAAATGACA TTATCCCATTCAGCACTGAAACAGAAGGAACCTCTACATCCTGTAAATGACAAAGAATCCTCTGAACAAGGTTCTGAAGTCAGTGAAGCA CAAACTACCGACAGTGATGATGTCATAGTGCCACCCATGTCTCAGAAATATCCTAAGGCAGATTCAGAGAAGATGTGCATTGAAATTGTC TCCCTGGCCTTCTACCCAGAGGCAGAAGTGATGTCTGATGAGAACATAAAACAGGTGTATGTGGAGTACAAATTCTACGACCTACCCTTG TCGGAGACAGAGACTCCAGTGTCCCTAAGGAAGCCTAGGGCAGGAGAAGAAATCCACTTTCACTTTAGCAAGGTAATAGACCTGGACCCA CAGGAGCAGCAAGGCCGAAGGCGGTTTCTGTTCGACATGCTGAATGGACAAGATCCTGATCAAGGACATTTAAAGTTTACAGTGGTAAGT GATCCTCTGGATGAAGAAAAGAAAGAATGTGAAGAAGTGGGATATGCATATCTTCAACTGTGGCAGATCCTGGAGTCAGGAAGAGATATT CTAGAGCAAGAGCTAGACATTGTTAGCCCTGAAGATCTGGCTACCCCAATAGGAAGGCTGAAGGTTTCCCTTCAAGCAGCTGCTGTCCTC CATGCTATTTACAAGGAGATGACTGAAGATTTGTTTTCATGAAGGAACAAGTGCTATTCCAATCTAAAAGTCTCTGAGGGAACCATAGTA |
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FusionGenePPI for STON2_RPGRIP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| STON2 | EPS15L1, EPS15, ITSN1, SYT2, SYT1, AP2M1, TOR1A, COPS4, ABL1, VCAM1, FN1, ITGA4, SLC25A41, CAPZA2, CLTB, CLTC, DBN1, FLNA, GAK, MYH9, PPP1CB, PICALM, SYNPO, RACGAP1, LIMA1, GTSE1, ANLN, MYO19, MYO18A, AP2S1, LSR, CLINT1 | RPGRIP1 | RPGR, CEBPA, BRCA1, IQCE, MAGEB2, ZNF337, HEYL, TFPT, TBC1D7, CHCHD3, DPPA4, FEM1C, CBX8, GATAD2B, CCDC146, TRIB3, AEN, SCNM1, CSPP1, RPP25L, ZNF417, ZNF564, FAM74A4, NPHP4, PTF1A, ACADSB, ADSL, CCDC22, CEP85, DLG5, ECD, HAUS8, HSD17B4, IBTK, IFT74, IPO5, KIAA1671, KIF14, NAP1L1, NAP1L4, RBM8A, SDCCAG3, TP53BP2, UNC45A, WDR83, CEP131, COMMD2, GPATCH1, HAUS6, IPO7, IPO8, IPO9, MKL1, NEK4, OFD1, PCM1, TNRC6B, TRIM37, METTL25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for STON2_RPGRIP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for STON2_RPGRIP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | STON2 | C0036341 | Schizophrenia | 2 | PSYGENET |
| Hgene | STON2 | C0001973 | Alcoholic Intoxication, Chronic | 1 | PSYGENET |
| Hgene | STON2 | C1842605 | SCHIZOPHRENIA 11 | 1 | PSYGENET |
| Tgene | RPGRIP1 | C1854260 | LEBER CONGENITAL AMAUROSIS 6 (disorder) | 5 | UNIPROT |
| Tgene | RPGRIP1 | C0339527 | Leber Congenital Amaurosis | 2 | CTD_human;ORPHANET |
| Tgene | RPGRIP1 | C2750720 | Cone-Rod Dystrophy 13 | 2 | CTD_human;UNIPROT |
| Tgene | RPGRIP1 | C0028738 | Nystagmus | 1 | CTD_human |
| Tgene | RPGRIP1 | C0035334 | Retinitis Pigmentosa | 1 | CTD_human;ORPHANET |
| Tgene | RPGRIP1 | C0854723 | Retinal Dystrophies | 1 | CTD_human |
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