FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 36387

FusionGeneSummary for STAT3_TPM3

check button Fusion gene summary
Fusion gene informationFusion gene name: STAT3_TPM3
Fusion gene ID: 36387
HgeneTgene
Gene symbol

STAT3

TPM3

Gene ID

6774

7170

Gene namesignal transducer and activator of transcription 3tropomyosin 3
SynonymsADMIO|ADMIO1|APRF|HIESCAPM1|CFTD|HEL-189|HEL-S-82p|NEM1|OK/SW-cl.5|TM-5|TM3|TM30|TM30nm|TM5|TPM3nu|TPMsk3|TRK|hscp30
Cytomap

17q21.2

1q21.3

Type of geneprotein-codingprotein-coding
Descriptionsignal transducer and activator of transcription 3DNA-binding protein APRFacute-phase response factortropomyosin alpha-3 chainalpha-tropomyosin, slow skeletalcytoskeletal tropomyosin TM30epididymis luminal protein 189epididymis secretory sperm binding protein Li 82pheat-stable cytoskeletal protein 30 kDatropomyosin 3 nutropomyosin gammatropomyosi
Modification date2018052720180523
UniProtAcc

P40763

P06753

Ensembl transtripts involved in fusion geneENST00000264657, ENST00000585517, 
ENST00000389272, ENST00000588969, 
ENST00000404395, ENST00000590776, 
ENST00000368533, ENST00000469717, 
ENST00000330188, ENST00000341485, 
ENST00000341372, ENST00000328159, 
ENST00000271850, ENST00000302206, 
ENST00000368531, ENST00000323144, 
ENST00000368530, 
Fusion gene scores* DoF score8 X 6 X 6=2887 X 6 X 4=168
# samples 89
** MAII scorelog2(8/288*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(9/168*10)=-0.900464326449086
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: STAT3 [Title/Abstract] AND TPM3 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotationTumor suppressor gene involved fusion gene, retained protein feature but frameshift.
DDR (DNA damage repair) gene involved fusion gene, in-frame but not retained their domain.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSTAT3

GO:0006355

regulation of transcription, DNA-templated

15664994|17344214

HgeneSTAT3

GO:0006606

protein import into nucleus

18234692

HgeneSTAT3

GO:0010628

positive regulation of gene expression

23820254

HgeneSTAT3

GO:0030522

intracellular receptor signaling pathway

17324931

HgeneSTAT3

GO:0032355

response to estradiol

12552091

HgeneSTAT3

GO:0032870

cellular response to hormone stimulus

12552091

HgeneSTAT3

GO:0033210

leptin-mediated signaling pathway

17344214

HgeneSTAT3

GO:0035278

miRNA mediated inhibition of translation

23820254

HgeneSTAT3

GO:0044320

cellular response to leptin stimulus

17344214

HgeneSTAT3

GO:0044321

response to leptin

17344214

HgeneSTAT3

GO:0045893

positive regulation of transcription, DNA-templated

19390056

HgeneSTAT3

GO:0045944

positive regulation of transcription by RNA polymerase II

17324931

HgeneSTAT3

GO:0051726

regulation of cell cycle

17344214

HgeneSTAT3

GO:0060396

growth hormone receptor signaling pathway

10925297

HgeneSTAT3

GO:0060397

JAK-STAT cascade involved in growth hormone signaling pathway

12552091

HgeneSTAT3

GO:0070102

interleukin-6-mediated signaling pathway

12359225|12552091|17324931

HgeneSTAT3

GO:1902895

positive regulation of pri-miRNA transcription by RNA polymerase II

19390056|23820254

HgeneSTAT3

GO:2000637

positive regulation of gene silencing by miRNA

23820254


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDLIHCTCGA-G3-A7M7-01ASTAT3chr17

40497577

-TPM3chr1

154148724

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shitENST00000264657ENST00000368533STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000264657ENST00000469717STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000264657ENST00000330188STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000264657ENST00000341485STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000264657ENST00000341372STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000264657ENST00000328159STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000264657ENST00000271850STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000264657ENST00000302206STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000264657ENST00000368531STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000264657ENST00000323144STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000264657ENST00000368530STAT3chr17

40497577

-TPM3chr1

154148724

-
Frame-shitENST00000585517ENST00000368533STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000585517ENST00000469717STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000585517ENST00000330188STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000585517ENST00000341485STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000585517ENST00000341372STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000585517ENST00000328159STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000585517ENST00000271850STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000585517ENST00000302206STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000585517ENST00000368531STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000585517ENST00000323144STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000585517ENST00000368530STAT3chr17

40497577

-TPM3chr1

154148724

-
Frame-shitENST00000389272ENST00000368533STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000389272ENST00000469717STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000389272ENST00000330188STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000389272ENST00000341485STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000389272ENST00000341372STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000389272ENST00000328159STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000389272ENST00000271850STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000389272ENST00000302206STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000389272ENST00000368531STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000389272ENST00000323144STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000389272ENST00000368530STAT3chr17

40497577

-TPM3chr1

154148724

-
Frame-shitENST00000588969ENST00000368533STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000588969ENST00000469717STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000588969ENST00000330188STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000588969ENST00000341485STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000588969ENST00000341372STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000588969ENST00000328159STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000588969ENST00000271850STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000588969ENST00000302206STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000588969ENST00000368531STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000588969ENST00000323144STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000588969ENST00000368530STAT3chr17

40497577

-TPM3chr1

154148724

-
Frame-shitENST00000404395ENST00000368533STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000404395ENST00000469717STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000404395ENST00000330188STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000404395ENST00000341485STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000404395ENST00000341372STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000404395ENST00000328159STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-intronENST00000404395ENST00000271850STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000404395ENST00000302206STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000404395ENST00000368531STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000404395ENST00000323144STAT3chr17

40497577

-TPM3chr1

154148724

-
5CDS-5UTRENST00000404395ENST00000368530STAT3chr17

40497577

-TPM3chr1

154148724

-
intron-3CDSENST00000590776ENST00000368533STAT3chr17

40497577

-TPM3chr1

154148724

-
intron-intronENST00000590776ENST00000469717STAT3chr17

40497577

-TPM3chr1

154148724

-
intron-intronENST00000590776ENST00000330188STAT3chr17

40497577

-TPM3chr1

154148724

-
intron-intronENST00000590776ENST00000341485STAT3chr17

40497577

-TPM3chr1

154148724

-
intron-intronENST00000590776ENST00000341372STAT3chr17

40497577

-TPM3chr1

154148724

-
intron-intronENST00000590776ENST00000328159STAT3chr17

40497577

-TPM3chr1

154148724

-
intron-intronENST00000590776ENST00000271850STAT3chr17

40497577

-TPM3chr1

154148724

-
intron-5UTRENST00000590776ENST00000302206STAT3chr17

40497577

-TPM3chr1

154148724

-
intron-5UTRENST00000590776ENST00000368531STAT3chr17

40497577

-TPM3chr1

154148724

-
intron-5UTRENST00000590776ENST00000323144STAT3chr17

40497577

-TPM3chr1

154148724

-
intron-5UTRENST00000590776ENST00000368530STAT3chr17

40497577

-TPM3chr1

154148724

-

Top

FusionProtFeatures for STAT3_TPM3


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
STAT3

P40763

TPM3

P06753

Signal transducer and transcription activator thatmediates cellular responses to interleukins, KITLG/SCF, LEP andother growth factors (PubMed:10688651, PubMed:12359225,PubMed:12873986, PubMed:15194700, PubMed:17344214,PubMed:18242580, PubMed:23084476). Once activated, recruitscoactivators, such as NCOA1 or MED1, to the promoter region of thetarget gene (PubMed:17344214). May mediate cellular responses toactivated FGFR1, FGFR2, FGFR3 and FGFR4 (PubMed:12873986). Bindsto the interleukin-6 (IL-6)-responsive elements identified in thepromoters of various acute-phase protein genes (PubMed:12359225).Activated by IL31 through IL31RA (PubMed:15194700). Acts as aregulator of inflammatory response by regulating differentiationof naive CD4(+) T-cells into T-helper Th17 or regulatory T-cells(Treg): deacetylation and oxidation of lysine residues by LOXL3,leads to disrupt STAT3 dimerization and inhibit its transcriptionactivity (PubMed:28065600). Involved in cell cycle regulation byinducing the expression of key genes for the progression from G1to S phase, such as CCND1 (PubMed:17344214). Mediates the effectsof LEP on melanocortin production, body energy homeostasis andlactation (By similarity). May play an apoptotic role bytransctivating BIRC5 expression under LEP activation(PubMed:18242580). Cytoplasmic STAT3 represses macroautophagy byinhibiting EIF2AK2/PKR activity (PubMed:23084476). Plays a crucialrole in basal beta cell functions, such as regulation of insulinsecretion (By similarity). {ECO:0000250|UniProtKB:P42227,ECO:0000269|PubMed:10688651, ECO:0000269|PubMed:12359225,ECO:0000269|PubMed:12873986, ECO:0000269|PubMed:15194700,ECO:0000269|PubMed:17344214, ECO:0000269|PubMed:18242580,ECO:0000269|PubMed:23084476, ECO:0000269|PubMed:28065600}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for STAT3_TPM3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

Top

FusionGenePPI for STAT3_TPM3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
STAT3RPA2, RET, EGFR, EPHA5, JAK1, TRIP10, AR, NR3C1, MYOD1, NDUFA13, KAT5, CREBBP, EP300, SMAD1, STAT1, PTPN11, IL1RAP, IL2RB, FES, NCOA1, ESR1, PIAS3, PTPN2, CCND1, HSP90AA1, KHDRBS1, ERBB2, MTOR, ELP2, PML, PTK2, JUN, IFNAR1, TSHR, HNF1A, IL6ST, PDIA3, NFKB1, RELA, IL6R, NMI, EIF2AK2, RAC1, SRC, BMX, GTF2I, CDKN1A, GHR, CCR5, JAK2, HIF1A, MET, CTR9, ALK, HOXC11, STAT6, SS18L1, PCBD2, SP1, BCL3, PELP1, DNMT1, HDAC1, RB1, HDAC2, HDAC3, STAT3, NFKBIZ, CEBPB, SMARCA4, CDK9, FGFR1, FGFR2, PPP2R1B, TIRAP, PRKCD, MAPK8, PGR, SIRT1, SETD7, KDM1A, RUNX2, ELAVL1, BHLHE40, CD44, DAXX, SOCS7, IRAK1, MAP3K7, MAPK1, FHL2, TRAF6, ZFHX3, APEX1, PTPN1, JAK3, TRIM28, HCK, LYN, FYN, FGR, HES1, HES5, SIN3A, BICD1, ECH1, SRI, SULT2A1, MRPS31, BCKDK, CORO1A, GNL3, OGDHL, NR4A1, CAPN1, MORC4, RPS9, HIVEP1, ASXL1, RPL11, NIF3L1, SUPT20H, HLA-A, AMBP, CAPNS1, LAMB2, HNRNPM, SIAH1, SIAH2, SCAF11, MAP3K13, SPRY1, SSSCA1, ZFPM2, ARFIP2, SRRT, ERBB2IP, IL22RA1, CEP120, LUC7L2, PSMG3, ARFIP1, IVNS1ABP, MSH2, PUS7, TBC1D15, TBCD, BRD4, ADRB2, COPS5, HIC1, USP22, GNB2, GADD45A, BLK, LMO2, SYK, SHMT2, MOV10, NXF1, NFKB2, AZU1, CACNG2, NXPH2, DDX19B, RP2, TRPV5, TCEAL1, IDE, NTRK1, BRWD1, FAM208B, CCDC87, DOK2, DOK3, FAM117B, GSTCD, HESX1, KRTAP10-7, MAPKAPK2, MPZL1, NUFIP2, PAQR7, PIK3R3, RABGAP1, SH2D2A, TM4SF19, TWIST1, VPS39, WDFY3, ZNF281, ZNF829, ABL2, CA8, CBL, DTNA, LASP1, LCK, PIK3R1, PIK3R2, PPARD, SH3BP2, BATF3, CHTF18, CNDP2, KLF15, NACAD, NXT2, OFCC1, PINK1, TDG, ZNF557, ATF3, MNDA, PAFAH1B2, IGF1R, PDGFRA, PDGFRB, STAT5B, ANKRD26P1, KIF27, PLA2G4A, LRRFIP2, HSP90B1, RRAD, FBXW7, STMN1, MAGEC2, RFWD2, CREB1, RELB, CDK15, LRRC32, IL20RA, TBC1D22B, TMEM206, MBLAC2, VASN, C3AR1, PVR, DLK2, ANXA2, TRIM25, TESTPM3KXD1, TFPT, MCC, EIF4A2, TPM3, TP73, NEK2, RAD21, ELAVL1, SP1, CUL3, CDK2, LRRK2, TPM4, SEC23IP, KYNU, TPM2, TPM1, PRDX1, THOC1, CDC123, SF3A2, SEPT9, HSPB1, BRCA1, MDC1, PAXIP1, HSP90AA1, HSP90AB1, FN1, PAN2, HDAC8, FBXO5, TRAP1, PARK2, FASN, FKBP4, FKBP5, MAGED2, CAP1, MCM3, MGEA5, TP53, HSF2, IFIT3, KCNE1, KIFC3, MAGEA11, PBX3, TRIM27, VPS52, TNNT1, TRIP6, MAD1L1, TLK1, OIP5, BLOC1S6, CCHCR1, THAP1, CCDC146, CCDC102B, CCDC114, SYCE1, IKBIP, C1orf216, LCA5L, FAM9C, HDDC3, WASH3P, LURAP1, SHMT2, MOV10, NXF1, CUL7, OBSL1, RNF2, EGFR, DAPK1, ACTN2, AHCYL1, ATP1A1, CKB, CKMT1B, CKMT1A, COX5A, CYC1, OSTF1, ACTN1, ACTN4, ATP5F1, COX4I1, MTCH1, MYH7B, NDUFB10, PSMA2, PSMA6, STMN1, TBCD, UQCRC2, NTRK1, DVL2, HOOK2, ADD1, CAPZA2, MYH9, PPP1CB, PPP1CC, IQGAP1, PDLIM7, ANLN, MYO5C, MYO19, MYO18A, MCM2, RNF20, IMP3, CALCOCO1, JUN, METTL2B, CCDC101, SPAG9, PARK7, PDHA1, VDAC1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for STAT3_TPM3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for STAT3_TPM3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSTAT3C3489795Hyper-Ige Recurrent Infection Syndrome, Autosomal Dominant4CTD_human;ORPHANET;UNIPROT
HgeneSTAT3C0018800Cardiomegaly3CTD_human
HgeneSTAT3C0033578Prostatic Neoplasms3CTD_human
HgeneSTAT3C0001418Adenocarcinoma2CTD_human
HgeneSTAT3C0007137Squamous cell carcinoma2CTD_human
HgeneSTAT3C0009324Ulcerative Colitis2CTD_human
HgeneSTAT3C0021368Inflammation2CTD_human
HgeneSTAT3C0027627Neoplasm Metastasis2CTD_human
HgeneSTAT3C0030297Pancreatic Neoplasm2CTD_human
HgeneSTAT3C0878544Cardiomyopathies2CTD_human
HgeneSTAT3C0004153Atherosclerosis1CTD_human
HgeneSTAT3C0004364Autoimmune Diseases1CTD_human;HPO
HgeneSTAT3C0007131Non-Small Cell Lung Carcinoma1CTD_human
HgeneSTAT3C0007621Neoplastic Cell Transformation1CTD_human
HgeneSTAT3C0007786Brain Ischemia1CTD_human
HgeneSTAT3C0007873Uterine Cervical Neoplasm1CTD_human
HgeneSTAT3C0009375Colonic Neoplasms1CTD_human
HgeneSTAT3C0011581Depressive disorder1PSYGENET
HgeneSTAT3C0011854Diabetes Mellitus, Insulin-Dependent1CTD_human
HgeneSTAT3C0015967Fever1CTD_human
HgeneSTAT3C0016059Fibrosis1CTD_human
HgeneSTAT3C0019189Hepatitis, Chronic1CTD_human
HgeneSTAT3C0023467Leukemia, Myelocytic, Acute1CTD_human
HgeneSTAT3C0023485Precursor B-Cell Lymphoblastic Leukemia-Lymphoma1CTD_human
HgeneSTAT3C0023492Leukemia, T-Cell1CTD_human
HgeneSTAT3C0023493Adult T-Cell Lymphoma/Leukemia1CTD_human
HgeneSTAT3C0023903Liver neoplasms1CTD_human
HgeneSTAT3C0024232Lymphatic Metastasis1CTD_human
HgeneSTAT3C0024667Animal Mammary Neoplasms1CTD_human
HgeneSTAT3C0024668Mammary Neoplasms, Experimental1CTD_human
HgeneSTAT3C0025149Medulloblastoma1CTD_human
HgeneSTAT3C0025261Memory Disorders1CTD_human
HgeneSTAT3C0033860Psoriasis1CTD_human
HgeneSTAT3C0035126Reperfusion Injury1CTD_human
HgeneSTAT3C0038356Stomach Neoplasms1CTD_human
HgeneSTAT3C0079772T-Cell Lymphoma1CTD_human
HgeneSTAT3C0206180Ki-1+ Anaplastic Large Cell Lymphoma1CTD_human
HgeneSTAT3C0235833Congenital diaphragmatic hernia1CTD_human
HgeneSTAT3C0333641Atrophic1CTD_human
HgeneSTAT3C0740392Infarction, Middle Cerebral Artery1CTD_human
HgeneSTAT3C0919267ovarian neoplasm1CTD_human
HgeneSTAT3C0993582Arthritis, Experimental1CTD_human
HgeneSTAT3C1168401Squamous cell carcinoma of the head and neck1CTD_human
HgeneSTAT3C1458155Mammary Neoplasms1CTD_human
HgeneSTAT3C1876165Copper-Overload Cirrhosis1CTD_human
HgeneSTAT3C3495559Juvenile arthritis1CTD_human
HgeneSTAT3C3887645Job Syndrome1CTD_human
HgeneSTAT3C4014795AUTOIMMUNE DISEASE, MULTISYSTEM, INFANTILE-ONSET1ORPHANET;UNIPROT
TgeneTPM3C1836448Nemaline myopathy 19CTD_human;ORPHANET;UNIPROT
TgeneTPM3C0546264Congenital Fiber Type Disproportion5ORPHANET;UNIPROT
TgeneTPM3C0024667Animal Mammary Neoplasms2CTD_human
TgeneTPM3C0024668Mammary Neoplasms, Experimental2CTD_human
TgeneTPM3C0001418Adenocarcinoma1CTD_human
TgeneTPM3C0009375Colonic Neoplasms1CTD_human
TgeneTPM3C0023893Liver Cirrhosis, Experimental1CTD_human
TgeneTPM3C0038356Stomach Neoplasms1CTD_human
TgeneTPM3C0040136Thyroid Neoplasm1CTD_human