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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 3619

FusionGeneSummary for AUTS2_ACTR1A

check button Fusion gene summary
Fusion gene informationFusion gene name: AUTS2_ACTR1A
Fusion gene ID: 3619
HgeneTgene
Gene symbol

AUTS2

ACTR1A

Gene ID

26053

10121

Gene nameAUTS2, activator of transcription and developmental regulatorARP1 actin related protein 1 homolog A
SynonymsFBRSL2|MRD26ARP1|Arp1A|CTRN1
Cytomap

7q11.22

10q24.32

Type of geneprotein-codingprotein-coding
Descriptionautism susceptibility gene 2 proteinautism susceptibility candidate 2autism-related protein 1alpha-centractinARP1 actin-related protein 1 homolog A, centractin alphaactin-RPVcentractincentrosome-associated actin homolog
Modification date2018051920180522
UniProtAcc

Q8WXX7

P61163

Ensembl transtripts involved in fusion geneENST00000406775, ENST00000342771, 
ENST00000403018, ENST00000489774, 
ENST00000369905, ENST00000470322, 
ENST00000487599, ENST00000545684, 
ENST00000446605, 
Fusion gene scores* DoF score19 X 15 X 7=19955 X 5 X 4=100
# samples 195
** MAII scorelog2(19/1995*10)=-3.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(5/100*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: AUTS2 [Title/Abstract] AND ACTR1A [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneAUTS2

GO:0045944

positive regulation of transcription by RNA polymerase II

25519132

HgeneAUTS2

GO:0051571

positive regulation of histone H3-K4 methylation

25519132

HgeneAUTS2

GO:2000620

positive regulation of histone H4-K16 acetylation

25519132


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVSARCTCGA-LI-A67I-01AAUTS2chr7

69364484

+ACTR1Achr10

104250370

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000406775ENST00000369905AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
5CDS-intronENST00000406775ENST00000470322AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
5CDS-intronENST00000406775ENST00000487599AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
5CDS-5UTRENST00000406775ENST00000545684AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
5CDS-intronENST00000406775ENST00000446605AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
In-frameENST00000342771ENST00000369905AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
5CDS-intronENST00000342771ENST00000470322AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
5CDS-intronENST00000342771ENST00000487599AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
5CDS-5UTRENST00000342771ENST00000545684AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
5CDS-intronENST00000342771ENST00000446605AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
In-frameENST00000403018ENST00000369905AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
5CDS-intronENST00000403018ENST00000470322AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
5CDS-intronENST00000403018ENST00000487599AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
5CDS-5UTRENST00000403018ENST00000545684AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
5CDS-intronENST00000403018ENST00000446605AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
intron-3CDSENST00000489774ENST00000369905AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
intron-intronENST00000489774ENST00000470322AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
intron-intronENST00000489774ENST00000487599AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
intron-5UTRENST00000489774ENST00000545684AUTS2chr7

69364484

+ACTR1Achr10

104250370

-
intron-intronENST00000489774ENST00000446605AUTS2chr7

69364484

+ACTR1Achr10

104250370

-

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FusionProtFeatures for AUTS2_ACTR1A


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
AUTS2

Q8WXX7

ACTR1A

P61163

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain thetranscriptionally repressive state of many genes, including Hoxgenes, throughout development. PcG PRC1 complex acts via chromatinremodeling and modification of histones; it mediatesmonoubiquitination of histone H2A 'Lys-119', rendering chromatinheritably changed in its expressibility (PubMed:25519132). ThePRC1-like complex that contains PCGF5, RNF2, CSNK2B, RYBP andAUTS2 has decreased histone H2A ubiquitination activity, due tothe phosphorylation of RNF2 by CSNK2B (PubMed:25519132). As aconsequence, the complex mediates transcriptional activation(PubMed:25519132). In the cytoplasm, plays a role in axon anddendrite elongation and in neuronal migration during embryonicbrain development. Promotes reorganization of the actincytoskeleton, lamellipodia formation and neurite elongation viaits interaction with RAC guanine nucleotide exchange factors,which then leads to the activation of RAC1 (By similarity).{ECO:0000250|UniProtKB:A0A087WPF7, ECO:0000269|PubMed:25519132}. Component of a multi-subunit complex involved inmicrotubule based vesicle motility. It is associated with thecentrosome.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneAUTS2chr7:69364484chr10:104250370ENST00000342771+2191122_11811741260Compositional biasHis-rich
HgeneAUTS2chr7:69364484chr10:104250370ENST00000342771+219288_4711741260Compositional biasPro-rich
HgeneAUTS2chr7:69364484chr10:104250370ENST00000342771+219525_5481741260Compositional biasHis-rich
HgeneAUTS2chr7:69364484chr10:104250370ENST00000342771+219545_6461741260Compositional biasPro-rich
HgeneAUTS2chr7:69364484chr10:104250370ENST00000403018+251122_1181174267Compositional biasHis-rich
HgeneAUTS2chr7:69364484chr10:104250370ENST00000403018+25288_471174267Compositional biasPro-rich
HgeneAUTS2chr7:69364484chr10:104250370ENST00000403018+25525_548174267Compositional biasHis-rich
HgeneAUTS2chr7:69364484chr10:104250370ENST00000403018+25545_646174267Compositional biasPro-rich
HgeneAUTS2chr7:69364484chr10:104250370ENST00000406775+2181122_11811741236Compositional biasHis-rich
HgeneAUTS2chr7:69364484chr10:104250370ENST00000406775+218288_4711741236Compositional biasPro-rich
HgeneAUTS2chr7:69364484chr10:104250370ENST00000406775+218525_5481741236Compositional biasHis-rich
HgeneAUTS2chr7:69364484chr10:104250370ENST00000406775+218545_6461741236Compositional biasPro-rich
HgeneAUTS2chr7:69364484chr10:104250370ENST00000342771+219289_4721741260RegionImportant for regulation of lamellipodia formation
HgeneAUTS2chr7:69364484chr10:104250370ENST00000403018+25289_472174267RegionImportant for regulation of lamellipodia formation
HgeneAUTS2chr7:69364484chr10:104250370ENST00000406775+218289_4721741236RegionImportant for regulation of lamellipodia formation


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FusionGeneSequence for AUTS2_ACTR1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_AUTS2_ENST00000406775_chr7_69364484_+_ACTR1A_ENST00000369905_chr10_104250370_-_535aa
MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDG
FAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQGSGVIK
AGFAGDQIPKYCFPNTVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRTPMEHGIVKDWNDMERIWQTVTSKDQLQTFSEEHPVLLTE
APLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPITEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEG
YDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRR

>In-frame_AUTS2_ENST00000342771_chr7_69364484_+_ACTR1A_ENST00000369905_chr10_104250370_-_535aa
MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDG
FAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQGSGVIK
AGFAGDQIPKYCFPNTVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRTPMEHGIVKDWNDMERIWQTVTSKDQLQTFSEEHPVLLTE
APLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPITEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEG
YDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRR

>In-frame_AUTS2_ENST00000403018_chr7_69364484_+_ACTR1A_ENST00000369905_chr10_104250370_-_535aa
MDGPTRGHGLRKKRRSRSQRDRERRSRGGLGAGAAGGGGAGRTRALSLASSSGSDKEDNGKPPSSAPSRPRPPRRKRRESTSAEEDIIDG
FAMTSFVTFEALEKDVALKPQERVEKRQTPLTKKKREALTNGLSFHSKKSRLSHPHHYSSDRENDRNLCQHLGKRKKMPKALRQGSGVIK
AGFAGDQIPKYCFPNTVGRPKHVRVMAGALEGDIFIGPKAEEHRGLLSIRTPMEHGIVKDWNDMERIWQTVTSKDQLQTFSEEHPVLLTE
APLNPRKNRERAAEVFFETFNVPALFISMQAVLSLYATGRTTGVVLDSGDGVTHAVPITEGFAMPHSIMRIDIAGRDVSRFLRLYLRKEG
YDFHSSSEFEIVKAIKERACYLSINPQKDETLETEKAQYYLPDGSTIEIGPSRFRAPELLFRPDLIGEESEGIHEVLVFAIQKSDMDLRR


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_AUTS2_ENST00000406775_chr7_69364484_+_ACTR1A_ENST00000369905_chr10_104250370_-_1605nt
ATGGATGGCCCGACGCGGGGCCATGGACTCCGCAAAAAGCGGCGGTCGCGGTCGCAGCGAGACCGGGAGAGGCGCTCCCGGGGCGGGCTG
GGGGCCGGCGCGGCCGGCGGCGGCGGGGCTGGCCGGACCCGGGCGCTCTCACTCGCCTCGTCGTCGGGCTCCGACAAGGAAGACAATGGG
AAGCCCCCGTCCTCCGCCCCGTCCCGGCCCAGACCCCCGCGGAGGAAGCGGAGAGAGTCCACCTCGGCAGAAGAGGACATCATTGATGGA
TTTGCCATGACCAGCTTTGTCACTTTTGAAGCGCTGGAGAAAGATGTAGCACTTAAGCCTCAGGAACGTGTGGAGAAACGCCAGACGCCC
CTGACCAAGAAGAAACGAGAAGCACTTACCAATGGCTTGTCCTTTCATTCAAAGAAGAGCAGACTCAGCCACCCACACCACTACAGCTCA
GATCGAGAAAATGACCGCAATCTCTGCCAGCACCTTGGGAAGAGAAAGAAAATGCCGAAGGCACTCAGACAGGGATCCGGTGTGATTAAA
GCTGGTTTTGCTGGTGATCAGATCCCCAAATACTGCTTTCCAAACTATGTGGGCCGACCCAAGCACGTTCGTGTCATGGCAGGAGCCCTT
GAAGGCGACATCTTCATTGGCCCCAAAGCTGAGGAGCACCGAGGGCTGCTTTCAATCCGCTATCCCATGGAGCATGGCATCGTCAAGGAT
TGGAACGACATGGAACGCATTTGGCAATATGTCTATTCTAAGGACCAGCTGCAGACTTTCTCAGAGGAGCATCCTGTGCTCCTGACTGAG
GCGCCTTTAAACCCACGAAAAAACCGGGAACGAGCTGCCGAAGTTTTCTTCGAGACCTTCAATGTGCCCGCTCTTTTCATCTCCATGCAA
GCTGTACTCAGCCTTTACGCTACAGGCAGGACCACAGGGGTGGTGCTGGATTCTGGGGATGGAGTCACCCATGCTGTGCCCATCTATGAG
GGCTTTGCCATGCCCCACTCCATCATGCGCATCGACATCGCGGGCCGGGACGTCTCTCGCTTCCTGCGCCTCTACCTGCGTAAGGAGGGC
TACGACTTCCACTCATCCTCTGAGTTTGAGATTGTCAAGGCCATAAAAGAAAGAGCCTGTTACCTATCCATAAACCCCCAAAAGGATGAG
ACGCTAGAGACAGAGAAAGCTCAGTACTACCTGCCTGATGGCAGCACCATTGAGATTGGTCCTTCCCGATTCCGGGCCCCTGAGTTGCTC
TTCAGGCCAGATTTGATTGGAGAGGAGAGTGAAGGCATCCACGAGGTCCTGGTGTTCGCCATTCAGAAGTCAGACATGGACCTGCGGCGC
ACGCTTTTCTCTAACATTGTCCTCTCAGGAGGCTCTACCCTGTTCAAAGGTTTTGGTGACAGGCTCCTGAGTGAAGTGAAGAAACTAGCT
CCAAAAGATGTGAAGATCAGGATATCTGCACCTCAGGAGAGACTGTATTCCACGTGGATTGGGGGCTCCATCCTTGCCTCCCTGGACACC

>In-frame_AUTS2_ENST00000342771_chr7_69364484_+_ACTR1A_ENST00000369905_chr10_104250370_-_1605nt
ATGGATGGCCCGACGCGGGGCCATGGACTCCGCAAAAAGCGGCGGTCGCGGTCGCAGCGAGACCGGGAGAGGCGCTCCCGGGGCGGGCTG
GGGGCCGGCGCGGCCGGCGGCGGCGGGGCTGGCCGGACCCGGGCGCTCTCACTCGCCTCGTCGTCGGGCTCCGACAAGGAAGACAATGGG
AAGCCCCCGTCCTCCGCCCCGTCCCGGCCCAGACCCCCGCGGAGGAAGCGGAGAGAGTCCACCTCGGCAGAAGAGGACATCATTGATGGA
TTTGCCATGACCAGCTTTGTCACTTTTGAAGCGCTGGAGAAAGATGTAGCACTTAAGCCTCAGGAACGTGTGGAGAAACGCCAGACGCCC
CTGACCAAGAAGAAACGAGAAGCACTTACCAATGGCTTGTCCTTTCATTCAAAGAAGAGCAGACTCAGCCACCCACACCACTACAGCTCA
GATCGAGAAAATGACCGCAATCTCTGCCAGCACCTTGGGAAGAGAAAGAAAATGCCGAAGGCACTCAGACAGGGATCCGGTGTGATTAAA
GCTGGTTTTGCTGGTGATCAGATCCCCAAATACTGCTTTCCAAACTATGTGGGCCGACCCAAGCACGTTCGTGTCATGGCAGGAGCCCTT
GAAGGCGACATCTTCATTGGCCCCAAAGCTGAGGAGCACCGAGGGCTGCTTTCAATCCGCTATCCCATGGAGCATGGCATCGTCAAGGAT
TGGAACGACATGGAACGCATTTGGCAATATGTCTATTCTAAGGACCAGCTGCAGACTTTCTCAGAGGAGCATCCTGTGCTCCTGACTGAG
GCGCCTTTAAACCCACGAAAAAACCGGGAACGAGCTGCCGAAGTTTTCTTCGAGACCTTCAATGTGCCCGCTCTTTTCATCTCCATGCAA
GCTGTACTCAGCCTTTACGCTACAGGCAGGACCACAGGGGTGGTGCTGGATTCTGGGGATGGAGTCACCCATGCTGTGCCCATCTATGAG
GGCTTTGCCATGCCCCACTCCATCATGCGCATCGACATCGCGGGCCGGGACGTCTCTCGCTTCCTGCGCCTCTACCTGCGTAAGGAGGGC
TACGACTTCCACTCATCCTCTGAGTTTGAGATTGTCAAGGCCATAAAAGAAAGAGCCTGTTACCTATCCATAAACCCCCAAAAGGATGAG
ACGCTAGAGACAGAGAAAGCTCAGTACTACCTGCCTGATGGCAGCACCATTGAGATTGGTCCTTCCCGATTCCGGGCCCCTGAGTTGCTC
TTCAGGCCAGATTTGATTGGAGAGGAGAGTGAAGGCATCCACGAGGTCCTGGTGTTCGCCATTCAGAAGTCAGACATGGACCTGCGGCGC
ACGCTTTTCTCTAACATTGTCCTCTCAGGAGGCTCTACCCTGTTCAAAGGTTTTGGTGACAGGCTCCTGAGTGAAGTGAAGAAACTAGCT
CCAAAAGATGTGAAGATCAGGATATCTGCACCTCAGGAGAGACTGTATTCCACGTGGATTGGGGGCTCCATCCTTGCCTCCCTGGACACC

>In-frame_AUTS2_ENST00000403018_chr7_69364484_+_ACTR1A_ENST00000369905_chr10_104250370_-_1605nt
ATGGATGGCCCGACGCGGGGCCATGGACTCCGCAAAAAGCGGCGGTCGCGGTCGCAGCGAGACCGGGAGAGGCGCTCCCGGGGCGGGCTG
GGGGCCGGCGCGGCCGGCGGCGGCGGGGCTGGCCGGACCCGGGCGCTCTCACTCGCCTCGTCGTCGGGCTCCGACAAGGAAGACAATGGG
AAGCCCCCGTCCTCCGCCCCGTCCCGGCCCAGACCCCCGCGGAGGAAGCGGAGAGAGTCCACCTCGGCAGAAGAGGACATCATTGATGGA
TTTGCCATGACCAGCTTTGTCACTTTTGAAGCGCTGGAGAAAGATGTAGCACTTAAGCCTCAGGAACGTGTGGAGAAACGCCAGACGCCC
CTGACCAAGAAGAAACGAGAAGCACTTACCAATGGCTTGTCCTTTCATTCAAAGAAGAGCAGACTCAGCCACCCACACCACTACAGCTCA
GATCGAGAAAATGACCGCAATCTCTGCCAGCACCTTGGGAAGAGAAAGAAAATGCCGAAGGCACTCAGACAGGGATCCGGTGTGATTAAA
GCTGGTTTTGCTGGTGATCAGATCCCCAAATACTGCTTTCCAAACTATGTGGGCCGACCCAAGCACGTTCGTGTCATGGCAGGAGCCCTT
GAAGGCGACATCTTCATTGGCCCCAAAGCTGAGGAGCACCGAGGGCTGCTTTCAATCCGCTATCCCATGGAGCATGGCATCGTCAAGGAT
TGGAACGACATGGAACGCATTTGGCAATATGTCTATTCTAAGGACCAGCTGCAGACTTTCTCAGAGGAGCATCCTGTGCTCCTGACTGAG
GCGCCTTTAAACCCACGAAAAAACCGGGAACGAGCTGCCGAAGTTTTCTTCGAGACCTTCAATGTGCCCGCTCTTTTCATCTCCATGCAA
GCTGTACTCAGCCTTTACGCTACAGGCAGGACCACAGGGGTGGTGCTGGATTCTGGGGATGGAGTCACCCATGCTGTGCCCATCTATGAG
GGCTTTGCCATGCCCCACTCCATCATGCGCATCGACATCGCGGGCCGGGACGTCTCTCGCTTCCTGCGCCTCTACCTGCGTAAGGAGGGC
TACGACTTCCACTCATCCTCTGAGTTTGAGATTGTCAAGGCCATAAAAGAAAGAGCCTGTTACCTATCCATAAACCCCCAAAAGGATGAG
ACGCTAGAGACAGAGAAAGCTCAGTACTACCTGCCTGATGGCAGCACCATTGAGATTGGTCCTTCCCGATTCCGGGCCCCTGAGTTGCTC
TTCAGGCCAGATTTGATTGGAGAGGAGAGTGAAGGCATCCACGAGGTCCTGGTGTTCGCCATTCAGAAGTCAGACATGGACCTGCGGCGC
ACGCTTTTCTCTAACATTGTCCTCTCAGGAGGCTCTACCCTGTTCAAAGGTTTTGGTGACAGGCTCCTGAGTGAAGTGAAGAAACTAGCT
CCAAAAGATGTGAAGATCAGGATATCTGCACCTCAGGAGAGACTGTATTCCACGTGGATTGGGGGCTCCATCCTTGCCTCCCTGGACACC


* Fusion transcript sequences (Full-length transcript).
>In-frame_AUTS2_ENST00000406775_chr7_69364484_+_ACTR1A_ENST00000369905_chr10_104250370_-_3974nt
CGCTCGCAGTTTCGCCCTCTCTTCCGCTAATGATTGCATTATTATGCTCCCCTCTCTGGGGGGTCTCGCCCCTCTTGGGTCGCTCCGGAG
CCCCGGCCTCCCCTGGCTGCATTTCTTAAAAATTTGGGAGCCTGGGAGTGAGTTTTCTCCGAGGCGTGTGTGAGAGGCGGCGGGGGTGTT
TTCCTGCGCGAGGGGCGGGTGAAGTTCATTGCCCCCACTTTTCCCGCGACCTTTTTCGGACCCGATTTTGGATCGAGTTGAGGGGGGCGC
GGGCGTTTTCGGGGGGCGGGGGGCGCGGCGGAGAATGGCCGCGGGGAGGGCTCCCCGGAGCCTCCCAGTCTCTTGATCAAAGCATTCCGC
TATTCTGATTTATTGCTTGCTTGGTGAGTTATTTTTTTTTCCTCTAAAGGAGACCTGTGTGTTCAGCCATTACTTTGCTCGGCGCTGCTC
CCAGGCATCTCCGACCCTCGGTGCTGTGGGGAGCCCCACACTTGGGCTCCTCGCCTCTCGCCCTCGCTCCCCGTCCCTCCTCCCCTCTCT
CCGCCCCTTCCCCCTTTTCTTTCTCCTCTCTTTCTTCCCCTCTCTCCCTTCTTTCGGCCGCCGTCTCCCCCGCGCCCTCCTCGGGGCGGA
GGGAAGCCGTGAAGGGGGAGGGAGGGCTCGGTGTCAATTTTTTTTTGTGTGGCTGCGGCCGTAGCCTGTGGCGGGCAAGCGGGGAGACCC
CGGCGCAGCAGAACCATGGATGGCCCGACGCGGGGCCATGGACTCCGCAAAAAGCGGCGGTCGCGGTCGCAGCGAGACCGGGAGAGGCGC
TCCCGGGGCGGGCTGGGGGCCGGCGCGGCCGGCGGCGGCGGGGCTGGCCGGACCCGGGCGCTCTCACTCGCCTCGTCGTCGGGCTCCGAC
AAGGAAGACAATGGGAAGCCCCCGTCCTCCGCCCCGTCCCGGCCCAGACCCCCGCGGAGGAAGCGGAGAGAGTCCACCTCGGCAGAAGAG
GACATCATTGATGGATTTGCCATGACCAGCTTTGTCACTTTTGAAGCGCTGGAGAAAGATGTAGCACTTAAGCCTCAGGAACGTGTGGAG
AAACGCCAGACGCCCCTGACCAAGAAGAAACGAGAAGCACTTACCAATGGCTTGTCCTTTCATTCAAAGAAGAGCAGACTCAGCCACCCA
CACCACTACAGCTCAGATCGAGAAAATGACCGCAATCTCTGCCAGCACCTTGGGAAGAGAAAGAAAATGCCGAAGGCACTCAGACAGGGA
TCCGGTGTGATTAAAGCTGGTTTTGCTGGTGATCAGATCCCCAAATACTGCTTTCCAAACTATGTGGGCCGACCCAAGCACGTTCGTGTC
ATGGCAGGAGCCCTTGAAGGCGACATCTTCATTGGCCCCAAAGCTGAGGAGCACCGAGGGCTGCTTTCAATCCGCTATCCCATGGAGCAT
GGCATCGTCAAGGATTGGAACGACATGGAACGCATTTGGCAATATGTCTATTCTAAGGACCAGCTGCAGACTTTCTCAGAGGAGCATCCT
GTGCTCCTGACTGAGGCGCCTTTAAACCCACGAAAAAACCGGGAACGAGCTGCCGAAGTTTTCTTCGAGACCTTCAATGTGCCCGCTCTT
TTCATCTCCATGCAAGCTGTACTCAGCCTTTACGCTACAGGCAGGACCACAGGGGTGGTGCTGGATTCTGGGGATGGAGTCACCCATGCT
GTGCCCATCTATGAGGGCTTTGCCATGCCCCACTCCATCATGCGCATCGACATCGCGGGCCGGGACGTCTCTCGCTTCCTGCGCCTCTAC
CTGCGTAAGGAGGGCTACGACTTCCACTCATCCTCTGAGTTTGAGATTGTCAAGGCCATAAAAGAAAGAGCCTGTTACCTATCCATAAAC
CCCCAAAAGGATGAGACGCTAGAGACAGAGAAAGCTCAGTACTACCTGCCTGATGGCAGCACCATTGAGATTGGTCCTTCCCGATTCCGG
GCCCCTGAGTTGCTCTTCAGGCCAGATTTGATTGGAGAGGAGAGTGAAGGCATCCACGAGGTCCTGGTGTTCGCCATTCAGAAGTCAGAC
ATGGACCTGCGGCGCACGCTTTTCTCTAACATTGTCCTCTCAGGAGGCTCTACCCTGTTCAAAGGTTTTGGTGACAGGCTCCTGAGTGAA
GTGAAGAAACTAGCTCCAAAAGATGTGAAGATCAGGATATCTGCACCTCAGGAGAGACTGTATTCCACGTGGATTGGGGGCTCCATCCTT
GCCTCCCTGGACACCTTTAAGAAGATGTGGGTCTCCAAAAAGGAATATGAGGAAGACGGTGCCCGATCCATCCACAGAAAAACCTTCTAA
TGTCGGGACATCATCTTCACCTCTCTCTGAAGTTAACTCCACTTTAAAACTCGCTTTCTTGAGTCGGAGTGTTTGCGAGGAACTGCCTGT
GTGTGAGTGCGTGTGTGGATATGAGTGTGTGTGCACATGCGAGTGCCGTGTGGCCCTGGGACCCTGGGCCCAGAAAGGACGATGAACTAC
CTGCAGTGGTGATGGCCTGAGGCCTGGGGTTGACCACTAACTGGCTCCTGACAGGGAAGAGCGCTGGCAGAGGCTGTGCTCCCTCCTCAG
GTGGCCTCTGGCTGGCTGTGGGGGACTCCGTTTACTACCACAGGGAGACAGAGGGAGGTAAGCCATCCCCCGGGAGACCTTGCTGCTGAC
CATCCTAGGCTGGGCTGGCCCCACCCTCACCCCCACCCCCAGGGTGCCCTGAGGCCCCAGGCAGCTGCTGCCTCCACTATCGATGCCTCC
TGACTGCACACTGAGGACTGGGACTGGGGTTGAGTTCTGTCTGGTTTTGTTGCCATTTTGGTTTGGGAGGCTGGAAAAGCACCCCAAGAG
CTATTACAGAGACTGGAGTCAGGAGAGAGCAGGAGGCCCTCATGTTCACCAGGGAACAGGACCACACCGGCCACTGGAGGAGGGCAGGAG
CAGTCCTCACTCTGAATGGCTGCAGAGTTAATGTTCCCAGCCCAGTCCCCTTTCGGGGGCCTTGGGAGAGTTTAAGGCACCTGCTGGTTC
CAGGACCTCGCTTTCCATCTGTTCTTGTTGCAATGCCATCTTCAAACCGTTTTATTTATTGAAGTGTTTGTTCAGTTAGGGGCTGGAGAG
AGGGAGCTTGCTGCCTCCTGCCTTGCTACACTAATGTTTACAGCACCTAAGCTTAGCCTCCAGGGCCCCACCTCTCCCAGCTGATGGTGA
GCTGACAGTGTCCACAGGTTCCAGGACCATTTGAGATTGGAAGCTACACTCAAAGACACTCCCACCAGGCTCTTTCTCCCTTTTCCTCTT
GCTCACTGCCCTGGAATCAACAGGCTGGTTGCTGGTTAGATTTTCTGAAACAGGAGGTAAAATTTTTCTTTGGCAGAGGCCCCTAAGCAA
GGGAGGGGTGTTGGAGAGCCAGTGCCCTTAAGACTGGAGAAAGCTGCAATTTACCAAGTTGCCTTTTGCCACTGTAGCTGACCAGGGGAC
TAGGTTGTAGAGGTGGGAAGGCCCCCTCTGGGCTGATCTTGTGCCATTCTTGACCTTGGACCTGCTTGGTTAAGGAGGGAGTGGGCCAGA
CCAGAGTGCCAGGAGCTAATGGAGCCAGGCCTGACTCCTAGGAGTGGTCCAAAGGCCTTCAGCCTAGATGGTGCAAAGCTGGGGCCAGCC
TGTCTTCACCGGCACCCTCACCTGTGACACCAAGACCCACCCCAATCCCAGACTTCACACAGTATTCTCCCCCACGCCGTCCTATGACCA
AAGGCCCCTGCCAGGTGTGGGCCACAGCAGCAGGTATGTGTGAAAGCAACGTAGCGCCCCGCGGACTGCAGTGCGCTTAACCAACTCACC
TCCCTTCTCTTAGCCCAAGCCTGTCCCTCGCACAGCCTCGCACAAACCACATTGCCTGGTGGGGCCCAGTGTACTGAAATAAAGTCGTTC

>In-frame_AUTS2_ENST00000342771_chr7_69364484_+_ACTR1A_ENST00000369905_chr10_104250370_-_3560nt
CTGTGTGTTCAGCCATTACTTTGCTCGGCGCTGCTCCCAGGCATCTCCGACCCTCGGTGCTGTGGGGAGCCCCACACTTGGGCTCCTCGC
CTCTCGCCCTCGCTCCCCGTCCCTCCTCCCCTCTCTCCGCCCCTTCCCCCTTTTCTTTCTCCTCTCTTTCTTCCCCTCTCTCCCTTCTTT
CGGCCGCCGTCTCCCCCGCGCCCTCCTCGGGGCGGAGGGAAGCCGTGAAGGGGGAGGGAGGGCTCGGTGTCAATTTTTTTTTGTGTGGCT
GCGGCCGTAGCCTGTGGCGGGCAAGCGGGGAGACCCCGGCGCAGCAGAACCATGGATGGCCCGACGCGGGGCCATGGACTCCGCAAAAAG
CGGCGGTCGCGGTCGCAGCGAGACCGGGAGAGGCGCTCCCGGGGCGGGCTGGGGGCCGGCGCGGCCGGCGGCGGCGGGGCTGGCCGGACC
CGGGCGCTCTCACTCGCCTCGTCGTCGGGCTCCGACAAGGAAGACAATGGGAAGCCCCCGTCCTCCGCCCCGTCCCGGCCCAGACCCCCG
CGGAGGAAGCGGAGAGAGTCCACCTCGGCAGAAGAGGACATCATTGATGGATTTGCCATGACCAGCTTTGTCACTTTTGAAGCGCTGGAG
AAAGATGTAGCACTTAAGCCTCAGGAACGTGTGGAGAAACGCCAGACGCCCCTGACCAAGAAGAAACGAGAAGCACTTACCAATGGCTTG
TCCTTTCATTCAAAGAAGAGCAGACTCAGCCACCCACACCACTACAGCTCAGATCGAGAAAATGACCGCAATCTCTGCCAGCACCTTGGG
AAGAGAAAGAAAATGCCGAAGGCACTCAGACAGGGATCCGGTGTGATTAAAGCTGGTTTTGCTGGTGATCAGATCCCCAAATACTGCTTT
CCAAACTATGTGGGCCGACCCAAGCACGTTCGTGTCATGGCAGGAGCCCTTGAAGGCGACATCTTCATTGGCCCCAAAGCTGAGGAGCAC
CGAGGGCTGCTTTCAATCCGCTATCCCATGGAGCATGGCATCGTCAAGGATTGGAACGACATGGAACGCATTTGGCAATATGTCTATTCT
AAGGACCAGCTGCAGACTTTCTCAGAGGAGCATCCTGTGCTCCTGACTGAGGCGCCTTTAAACCCACGAAAAAACCGGGAACGAGCTGCC
GAAGTTTTCTTCGAGACCTTCAATGTGCCCGCTCTTTTCATCTCCATGCAAGCTGTACTCAGCCTTTACGCTACAGGCAGGACCACAGGG
GTGGTGCTGGATTCTGGGGATGGAGTCACCCATGCTGTGCCCATCTATGAGGGCTTTGCCATGCCCCACTCCATCATGCGCATCGACATC
GCGGGCCGGGACGTCTCTCGCTTCCTGCGCCTCTACCTGCGTAAGGAGGGCTACGACTTCCACTCATCCTCTGAGTTTGAGATTGTCAAG
GCCATAAAAGAAAGAGCCTGTTACCTATCCATAAACCCCCAAAAGGATGAGACGCTAGAGACAGAGAAAGCTCAGTACTACCTGCCTGAT
GGCAGCACCATTGAGATTGGTCCTTCCCGATTCCGGGCCCCTGAGTTGCTCTTCAGGCCAGATTTGATTGGAGAGGAGAGTGAAGGCATC
CACGAGGTCCTGGTGTTCGCCATTCAGAAGTCAGACATGGACCTGCGGCGCACGCTTTTCTCTAACATTGTCCTCTCAGGAGGCTCTACC
CTGTTCAAAGGTTTTGGTGACAGGCTCCTGAGTGAAGTGAAGAAACTAGCTCCAAAAGATGTGAAGATCAGGATATCTGCACCTCAGGAG
AGACTGTATTCCACGTGGATTGGGGGCTCCATCCTTGCCTCCCTGGACACCTTTAAGAAGATGTGGGTCTCCAAAAAGGAATATGAGGAA
GACGGTGCCCGATCCATCCACAGAAAAACCTTCTAATGTCGGGACATCATCTTCACCTCTCTCTGAAGTTAACTCCACTTTAAAACTCGC
TTTCTTGAGTCGGAGTGTTTGCGAGGAACTGCCTGTGTGTGAGTGCGTGTGTGGATATGAGTGTGTGTGCACATGCGAGTGCCGTGTGGC
CCTGGGACCCTGGGCCCAGAAAGGACGATGAACTACCTGCAGTGGTGATGGCCTGAGGCCTGGGGTTGACCACTAACTGGCTCCTGACAG
GGAAGAGCGCTGGCAGAGGCTGTGCTCCCTCCTCAGGTGGCCTCTGGCTGGCTGTGGGGGACTCCGTTTACTACCACAGGGAGACAGAGG
GAGGTAAGCCATCCCCCGGGAGACCTTGCTGCTGACCATCCTAGGCTGGGCTGGCCCCACCCTCACCCCCACCCCCAGGGTGCCCTGAGG
CCCCAGGCAGCTGCTGCCTCCACTATCGATGCCTCCTGACTGCACACTGAGGACTGGGACTGGGGTTGAGTTCTGTCTGGTTTTGTTGCC
ATTTTGGTTTGGGAGGCTGGAAAAGCACCCCAAGAGCTATTACAGAGACTGGAGTCAGGAGAGAGCAGGAGGCCCTCATGTTCACCAGGG
AACAGGACCACACCGGCCACTGGAGGAGGGCAGGAGCAGTCCTCACTCTGAATGGCTGCAGAGTTAATGTTCCCAGCCCAGTCCCCTTTC
GGGGGCCTTGGGAGAGTTTAAGGCACCTGCTGGTTCCAGGACCTCGCTTTCCATCTGTTCTTGTTGCAATGCCATCTTCAAACCGTTTTA
TTTATTGAAGTGTTTGTTCAGTTAGGGGCTGGAGAGAGGGAGCTTGCTGCCTCCTGCCTTGCTACACTAATGTTTACAGCACCTAAGCTT
AGCCTCCAGGGCCCCACCTCTCCCAGCTGATGGTGAGCTGACAGTGTCCACAGGTTCCAGGACCATTTGAGATTGGAAGCTACACTCAAA
GACACTCCCACCAGGCTCTTTCTCCCTTTTCCTCTTGCTCACTGCCCTGGAATCAACAGGCTGGTTGCTGGTTAGATTTTCTGAAACAGG
AGGTAAAATTTTTCTTTGGCAGAGGCCCCTAAGCAAGGGAGGGGTGTTGGAGAGCCAGTGCCCTTAAGACTGGAGAAAGCTGCAATTTAC
CAAGTTGCCTTTTGCCACTGTAGCTGACCAGGGGACTAGGTTGTAGAGGTGGGAAGGCCCCCTCTGGGCTGATCTTGTGCCATTCTTGAC
CTTGGACCTGCTTGGTTAAGGAGGGAGTGGGCCAGACCAGAGTGCCAGGAGCTAATGGAGCCAGGCCTGACTCCTAGGAGTGGTCCAAAG
GCCTTCAGCCTAGATGGTGCAAAGCTGGGGCCAGCCTGTCTTCACCGGCACCCTCACCTGTGACACCAAGACCCACCCCAATCCCAGACT
TCACACAGTATTCTCCCCCACGCCGTCCTATGACCAAAGGCCCCTGCCAGGTGTGGGCCACAGCAGCAGGTATGTGTGAAAGCAACGTAG
CGCCCCGCGGACTGCAGTGCGCTTAACCAACTCACCTCCCTTCTCTTAGCCCAAGCCTGTCCCTCGCACAGCCTCGCACAAACCACATTG

>In-frame_AUTS2_ENST00000403018_chr7_69364484_+_ACTR1A_ENST00000369905_chr10_104250370_-_3282nt
AGCCTGTGGCGGGCAAGCGGGGAGACCCCGGCGCAGCAGAACCATGGATGGCCCGACGCGGGGCCATGGACTCCGCAAAAAGCGGCGGTC
GCGGTCGCAGCGAGACCGGGAGAGGCGCTCCCGGGGCGGGCTGGGGGCCGGCGCGGCCGGCGGCGGCGGGGCTGGCCGGACCCGGGCGCT
CTCACTCGCCTCGTCGTCGGGCTCCGACAAGGAAGACAATGGGAAGCCCCCGTCCTCCGCCCCGTCCCGGCCCAGACCCCCGCGGAGGAA
GCGGAGAGAGTCCACCTCGGCAGAAGAGGACATCATTGATGGATTTGCCATGACCAGCTTTGTCACTTTTGAAGCGCTGGAGAAAGATGT
AGCACTTAAGCCTCAGGAACGTGTGGAGAAACGCCAGACGCCCCTGACCAAGAAGAAACGAGAAGCACTTACCAATGGCTTGTCCTTTCA
TTCAAAGAAGAGCAGACTCAGCCACCCACACCACTACAGCTCAGATCGAGAAAATGACCGCAATCTCTGCCAGCACCTTGGGAAGAGAAA
GAAAATGCCGAAGGCACTCAGACAGGGATCCGGTGTGATTAAAGCTGGTTTTGCTGGTGATCAGATCCCCAAATACTGCTTTCCAAACTA
TGTGGGCCGACCCAAGCACGTTCGTGTCATGGCAGGAGCCCTTGAAGGCGACATCTTCATTGGCCCCAAAGCTGAGGAGCACCGAGGGCT
GCTTTCAATCCGCTATCCCATGGAGCATGGCATCGTCAAGGATTGGAACGACATGGAACGCATTTGGCAATATGTCTATTCTAAGGACCA
GCTGCAGACTTTCTCAGAGGAGCATCCTGTGCTCCTGACTGAGGCGCCTTTAAACCCACGAAAAAACCGGGAACGAGCTGCCGAAGTTTT
CTTCGAGACCTTCAATGTGCCCGCTCTTTTCATCTCCATGCAAGCTGTACTCAGCCTTTACGCTACAGGCAGGACCACAGGGGTGGTGCT
GGATTCTGGGGATGGAGTCACCCATGCTGTGCCCATCTATGAGGGCTTTGCCATGCCCCACTCCATCATGCGCATCGACATCGCGGGCCG
GGACGTCTCTCGCTTCCTGCGCCTCTACCTGCGTAAGGAGGGCTACGACTTCCACTCATCCTCTGAGTTTGAGATTGTCAAGGCCATAAA
AGAAAGAGCCTGTTACCTATCCATAAACCCCCAAAAGGATGAGACGCTAGAGACAGAGAAAGCTCAGTACTACCTGCCTGATGGCAGCAC
CATTGAGATTGGTCCTTCCCGATTCCGGGCCCCTGAGTTGCTCTTCAGGCCAGATTTGATTGGAGAGGAGAGTGAAGGCATCCACGAGGT
CCTGGTGTTCGCCATTCAGAAGTCAGACATGGACCTGCGGCGCACGCTTTTCTCTAACATTGTCCTCTCAGGAGGCTCTACCCTGTTCAA
AGGTTTTGGTGACAGGCTCCTGAGTGAAGTGAAGAAACTAGCTCCAAAAGATGTGAAGATCAGGATATCTGCACCTCAGGAGAGACTGTA
TTCCACGTGGATTGGGGGCTCCATCCTTGCCTCCCTGGACACCTTTAAGAAGATGTGGGTCTCCAAAAAGGAATATGAGGAAGACGGTGC
CCGATCCATCCACAGAAAAACCTTCTAATGTCGGGACATCATCTTCACCTCTCTCTGAAGTTAACTCCACTTTAAAACTCGCTTTCTTGA
GTCGGAGTGTTTGCGAGGAACTGCCTGTGTGTGAGTGCGTGTGTGGATATGAGTGTGTGTGCACATGCGAGTGCCGTGTGGCCCTGGGAC
CCTGGGCCCAGAAAGGACGATGAACTACCTGCAGTGGTGATGGCCTGAGGCCTGGGGTTGACCACTAACTGGCTCCTGACAGGGAAGAGC
GCTGGCAGAGGCTGTGCTCCCTCCTCAGGTGGCCTCTGGCTGGCTGTGGGGGACTCCGTTTACTACCACAGGGAGACAGAGGGAGGTAAG
CCATCCCCCGGGAGACCTTGCTGCTGACCATCCTAGGCTGGGCTGGCCCCACCCTCACCCCCACCCCCAGGGTGCCCTGAGGCCCCAGGC
AGCTGCTGCCTCCACTATCGATGCCTCCTGACTGCACACTGAGGACTGGGACTGGGGTTGAGTTCTGTCTGGTTTTGTTGCCATTTTGGT
TTGGGAGGCTGGAAAAGCACCCCAAGAGCTATTACAGAGACTGGAGTCAGGAGAGAGCAGGAGGCCCTCATGTTCACCAGGGAACAGGAC
CACACCGGCCACTGGAGGAGGGCAGGAGCAGTCCTCACTCTGAATGGCTGCAGAGTTAATGTTCCCAGCCCAGTCCCCTTTCGGGGGCCT
TGGGAGAGTTTAAGGCACCTGCTGGTTCCAGGACCTCGCTTTCCATCTGTTCTTGTTGCAATGCCATCTTCAAACCGTTTTATTTATTGA
AGTGTTTGTTCAGTTAGGGGCTGGAGAGAGGGAGCTTGCTGCCTCCTGCCTTGCTACACTAATGTTTACAGCACCTAAGCTTAGCCTCCA
GGGCCCCACCTCTCCCAGCTGATGGTGAGCTGACAGTGTCCACAGGTTCCAGGACCATTTGAGATTGGAAGCTACACTCAAAGACACTCC
CACCAGGCTCTTTCTCCCTTTTCCTCTTGCTCACTGCCCTGGAATCAACAGGCTGGTTGCTGGTTAGATTTTCTGAAACAGGAGGTAAAA
TTTTTCTTTGGCAGAGGCCCCTAAGCAAGGGAGGGGTGTTGGAGAGCCAGTGCCCTTAAGACTGGAGAAAGCTGCAATTTACCAAGTTGC
CTTTTGCCACTGTAGCTGACCAGGGGACTAGGTTGTAGAGGTGGGAAGGCCCCCTCTGGGCTGATCTTGTGCCATTCTTGACCTTGGACC
TGCTTGGTTAAGGAGGGAGTGGGCCAGACCAGAGTGCCAGGAGCTAATGGAGCCAGGCCTGACTCCTAGGAGTGGTCCAAAGGCCTTCAG
CCTAGATGGTGCAAAGCTGGGGCCAGCCTGTCTTCACCGGCACCCTCACCTGTGACACCAAGACCCACCCCAATCCCAGACTTCACACAG
TATTCTCCCCCACGCCGTCCTATGACCAAAGGCCCCTGCCAGGTGTGGGCCACAGCAGCAGGTATGTGTGAAAGCAACGTAGCGCCCCGC
GGACTGCAGTGCGCTTAACCAACTCACCTCCCTTCTCTTAGCCCAAGCCTGTCCCTCGCACAGCCTCGCACAAACCACATTGCCTGGTGG


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FusionGenePPI for AUTS2_ACTR1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
AUTS2PCGF3, PCGF5, RNF2, CSNK2A2, RYBP, RING1, YAF2, CSNK2A1, CSNK2B, DCAF7, FBRS, EP300, RERE, RBM14, ZNF608, ZNF609, TLE3, WDR5, PCGF6, ATN1ACTR1ANUMA1, BICD2, SPTBN2, DCTN4, HDAC6, UBC, CUL3, CUL1, COPS5, DCTN2, ACTR1B, PSMC4, MYH9, PSMD1, RRS1, MCM7, SMURF1, ACTR10, COG3, DCTN3, LMNB1, MYCBP, NUP133, HUWE1, MOV10, NXF1, CAPZA2, ACADSB, CAD, CCAR1, CDC45, KPNA3, KPNA4, SF3A1, SF3A3, UBR5, ZW10, DCTN1, DCTN5, PACSIN3, POLR2D, NTRK1, MED4, NIN, DYNC1H1, MAPRE1, IWS1, ZFC3H1, SNW1, CDC5L, DUSP13, DCTN6, KLHL2, DEFB127, RIC8A, PDGFD, C16orf45, MIS18A, C1orf106, CYLD, DLD, DNM1L, G3BP1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for AUTS2_ACTR1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for AUTS2_ACTR1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneAUTS2C0036341Schizophrenia2PSYGENET
HgeneAUTS2C0014544Epilepsy1CTD_human