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Fusion gene ID: 36148 |
FusionGeneSummary for SSH2_ASAP1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SSH2_ASAP1 | Fusion gene ID: 36148 | Hgene | Tgene | Gene symbol | SSH2 | ASAP1 | Gene ID | 85464 | 50807 |
| Gene name | slingshot protein phosphatase 2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | |
| Synonyms | SSH-2|SSH-2L | AMAP1|CENTB4|DDEF1|PAG2|PAP|ZG14P | |
| Cytomap | 17q11.2 | 8q24.21-q24.22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | protein phosphatase Slingshot homolog 2SSH-like protein 2 | arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating proteinADP-ribosyl | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q76I76 | Q9ULH1 | |
| Ensembl transtripts involved in fusion gene | ENST00000269033, ENST00000540801, ENST00000324677, ENST00000582084, ENST00000590153, ENST00000579954, | ENST00000357668, ENST00000518721, ENST00000520625, | |
| Fusion gene scores | * DoF score | 24 X 11 X 6=1584 | 6 X 6 X 3=108 |
| # samples | 24 | 6 | |
| ** MAII score | log2(24/1584*10)=-2.72246602447109 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/108*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SSH2 [Title/Abstract] AND ASAP1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-A8-A07R-01A | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000269033 | ENST00000357668 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| 5CDS-5UTR | ENST00000269033 | ENST00000518721 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| 5CDS-intron | ENST00000269033 | ENST00000520625 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| In-frame | ENST00000540801 | ENST00000357668 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| 5CDS-5UTR | ENST00000540801 | ENST00000518721 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| 5CDS-intron | ENST00000540801 | ENST00000520625 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| intron-3CDS | ENST00000324677 | ENST00000357668 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| intron-5UTR | ENST00000324677 | ENST00000518721 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| intron-intron | ENST00000324677 | ENST00000520625 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| Frame-shift | ENST00000582084 | ENST00000357668 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| 5CDS-5UTR | ENST00000582084 | ENST00000518721 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| 5CDS-intron | ENST00000582084 | ENST00000520625 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| In-frame | ENST00000590153 | ENST00000357668 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| 5CDS-5UTR | ENST00000590153 | ENST00000518721 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| 5CDS-intron | ENST00000590153 | ENST00000520625 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| In-frame | ENST00000579954 | ENST00000357668 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| 5CDS-5UTR | ENST00000579954 | ENST00000518721 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
| 5CDS-intron | ENST00000579954 | ENST00000520625 | SSH2 | chr17 | 28256956 | - | ASAP1 | chr8 | 131414216 | - |
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FusionProtFeatures for SSH2_ASAP1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SSH2 | ASAP1 |
| Protein phosphatase which regulates actin filamentdynamics. Dephosphorylates and activates the actinbinding/depolymerizing factor cofilin, which subsequently binds toactin filaments and stimulates their disassembly. Inhibitoryphosphorylation of cofilin is mediated by LIMK1, which may also bedephosphorylated and inactivated by this protein.{ECO:0000269|PubMed:11832213}. | Possesses phosphatidylinositol 4,5-bisphosphate-dependent GTPase-activating protein activity for ARF1 (ADPribosylation factor 1) and ARF5 and a lesser activity towardsARF6. May coordinate membrane trafficking with cell growth oractin cytoskeleton remodeling by binding to both SRC and PIP2. Mayfunction as a signal transduction protein involved in thedifferentiation of fibroblasts into adipocytes and possibly othercell types (By similarity). Plays a role in ciliogenesis.{ECO:0000250, ECO:0000269|PubMed:20393563}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000357668 | - | -1 | 29 | 783_993 | 19 | 1130 | Compositional bias | Note=Pro-rich |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000518721 | - | 0 | 30 | 783_993 | -9 | 1130 | Compositional bias | Note=Pro-rich |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000357668 | - | -1 | 29 | 1067_1129 | 19 | 1130 | Domain | SH3 |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000357668 | - | -1 | 29 | 324_416 | 19 | 1130 | Domain | PH |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000357668 | - | -1 | 29 | 439_560 | 19 | 1130 | Domain | Arf-GAP |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000518721 | - | 0 | 30 | 1067_1129 | -9 | 1130 | Domain | SH3 |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000518721 | - | 0 | 30 | 324_416 | -9 | 1130 | Domain | PH |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000518721 | - | 0 | 30 | 439_560 | -9 | 1130 | Domain | Arf-GAP |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000357668 | - | -1 | 29 | 600_632 | 19 | 1130 | Repeat | Note=ANK 1 |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000357668 | - | -1 | 29 | 636_665 | 19 | 1130 | Repeat | Note=ANK 2 |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000518721 | - | 0 | 30 | 600_632 | -9 | 1130 | Repeat | Note=ANK 1 |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000518721 | - | 0 | 30 | 636_665 | -9 | 1130 | Repeat | Note=ANK 2 |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000357668 | - | -1 | 29 | 454_477 | 19 | 1130 | Zinc finger | C4-type |
| Tgene | >ASAP1 | chr17:28256956 | chr8:131414216 | ENST00000518721 | - | 0 | 30 | 454_477 | -9 | 1130 | Zinc finger | C4-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SSH2 | chr17:28256956 | chr8:131414216 | ENST00000269033 | - | 1 | 15 | 307_447 | 21 | 1424 | Domain | Note=Tyrosine-protein phosphatase |
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FusionGeneSequence for SSH2_ASAP1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SSH2_ENST00000269033_chr17_28256956_-_ASAP1_ENST00000357668_chr8_131414216_-_21aa >In-frame_SSH2_ENST00000540801_chr17_28256956_-_ASAP1_ENST00000357668_chr8_131414216_-_21aa >In-frame_SSH2_ENST00000590153_chr17_28256956_-_ASAP1_ENST00000357668_chr8_131414216_-_21aa >In-frame_SSH2_ENST00000579954_chr17_28256956_-_ASAP1_ENST00000357668_chr8_131414216_-_21aa |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SSH2_ENST00000269033_chr17_28256956_-_ASAP1_ENST00000357668_chr8_131414216_-_63nt >In-frame_SSH2_ENST00000540801_chr17_28256956_-_ASAP1_ENST00000357668_chr8_131414216_-_63nt >In-frame_SSH2_ENST00000590153_chr17_28256956_-_ASAP1_ENST00000357668_chr8_131414216_-_63nt >In-frame_SSH2_ENST00000579954_chr17_28256956_-_ASAP1_ENST00000357668_chr8_131414216_-_63nt |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SSH2_ENST00000269033_chr17_28256956_-_ASAP1_ENST00000357668_chr8_131414216_-_6257nt GCGGAGTCTGCGGCCGTTCCCGCGGCCTCCTCCTCCTCCCCGTTCCCTTCACCCCCACCCCGCACCCCTTTCCCCATCCCGGCTCCGTCA CCCTCCCGTCCCCCACACTCAGGACAAGAATGCCCTGCCCGGAACAACCCAGCAGCGCCTAGATGGCTTTGGTCACGGTCCAGCGGTCAC CTACCCCCAGCACCACCTCCAGCCCCTGCGCCTCGGGTCGTTTTCTGATGTGACGGCTGAGACATGAGATCTTCAGCCTCCAGGCTCTCC AGTTTTTCGTCGAGAGATTCACTATGGAATCGGATGCCGGACCAGATCTCTGTCTCGGAGTTCATCGCCGAGACCACCGAGGACTACAAC TCGCCCACCACGTCCAGCTTCACCACGCGGCTGCACAACTGCAGGAACACCGTCACGCTGCTGGAGGAGGCTCTAGACCAAGATAGAACA GCCCTTCAGAAAGTGAAGAAGTCTGTAAAAGCAATATATAATTCTGGTCAAGATCATGTACAAAATGAAGAAAACTATGCACAAGTTCTT GATAAGTTTGGGAGTAATTTTTTAAGTCGAGACAACCCCGACCTTGGCACCGCGTTTGTCAAGTTTTCTACTCTTACAAAGGAACTGTCC ACACTGCTGAAAAATCTGCTCCAGGGTTTGAGCCACAATGTGATCTTCACCTTGGATTCTTTGTTAAAAGGAGACCTAAAGGGAGTCAAA GGAGATCTCAAGAAGCCATTTGACAAAGCCTGGAAAGATTATGAGACAAAGTTTACAAAAATTGAGAAAGAGAAAAGAGAGCACGCAAAA CAACATGGGATGATCCGCACAGAGATAACAGGAGCTGAGATTGCGGAAGAAATGGAGAAGGAAAGGCGCCTCTTTCAGCTCCAAATGTGT GAATATCTCATTAAAGTTAATGAAATCAAGACCAAAAAGGGTGTGGATCTGCTGCAGAATCTTATAAAGTATTACCATGCACAGTGCAAT TTCTTTCAAGATGGCTTGAAAACAGCTGATAAGTTGAAACAGTACATTGAAAAACTGGCTGCTGATTTATATAATATAAAACAGACCCAG GATGAAGAAAAGAAACAGCTAACTGCACTCCGAGACTTAATAAAATCCTCTCTTCAACTGGATCAGAAAGAAGATTCTCAGAGCCGGCAA GGAGGATACAGCATGCATCAGCTCCAGGGCAATAAGGAATATGGCAGTGAAAAGAAGGGGTACCTGCTAAAGAAAAGTGACGGGATCCGG AAAGTATGGCAGAGGAGGAAGTGTTCAGTCAAGAATGGGATTCTGACCATCTCACATGCCACATCTAACAGGCAACCAGCCAAGTTGAAC CTTCTCACCTGCCAAGTAAAACCTAATGCCGAAGACAAAAAATCTTTTGACCTGATATCACATAATAGAACATATCACTTTCAGGCAGAA GATGAGCAGGATTATGTAGCATGGATATCAGTATTGACAAATAGCAAAGAAGAGGCCCTAACCATGGCCTTCCGTGGAGAGCAGAGTGCG GGAGAGAACAGCCTGGAAGACCTGACAAAAGCCATTATTGAGGATGTCCAGCGGCTCCCAGGGAATGACATTTGCTGCGATTGTGGCTCA TCAGAACCCACCTGGCTTTCAACCAACTTGGGTATTTTGACCTGTATAGAATGTTCTGGCATCCATAGGGAAATGGGGGTTCATATTTCT CGCATTCAGTCTTTGGAACTAGACAAATTAGGAACTTCTGAACTCTTGCTGGCCAAGAATGTAGGAAACAATAGTTTTAATGATATTATG GAAGCAAATTTACCCAGCCCCTCACCAAAACCCACCCCTTCAAGTGATATGACTGTACGAAAAGAATATATCACTGCAAAGTATGTAGAT CATAGGTTTTCAAGGAAGACCTGTTCAACTTCATCAGCTAAACTAAATGAATTGCTTGAGGCCATCAAATCCAGGGATTTACTTGCACTA ATTCAAGTCTATGCAGAAGGGGTAGAGCTAATGGAACCACTGCTGGAACCTGGGCAGGAGCTTGGGGAGACAGCCCTTCACCTTGCCGTC CGAACTGCAGATCAGACATCTCTCCATTTGGTTGACTTCCTTGTACAAAACTGTGGGAACCTGGATAAGCAGACGGCCCTGGGAAACACA GTTCTACACTACTGTAGTATGTACAGTAAACCTGAGTGTTTGAAGCTTTTGCTCAGGAGCAAGCCCACTGTGGATATAGTTAACCAGGCT GGAGAAACTGCCCTAGACATAGCAAAGAGACTAAAAGCTACCCAGTGTGAAGATCTGCTTTCCCAGGCTAAATCTGGAAAGTTCAATCCA CACGTCCACGTAGAATATGAGTGGAATCTTCGACAGGAGGAGATAGATGAGAGCGATGATGATCTGGATGACAAACCAAGCCCTATCAAG AAAGAGCGCTCACCCAGACCTCAGAGCTTCTGCCACTCCTCCAGCATCTCCCCCCAGGACAAGCTGGCACTGCCAGGATTCAGCACTCCA AGGGACAAACAGCGGCTCTCCTATGGAGCCTTCACCAACCAGATCTTCGTTTCCACAAGCACAGACTCGCCCACATCACCAACCACGGAG GCTCCCCCTCTGCCTCCTAGGAACGCCGGGAAAGGTCCAACTGGCCCACCTTCAACACTCCCTCTAAGCACCCAGACCTCTAGTGGCAGC TCCACCCTATCCAAGAAGAGGCCTCCTCCCCCACCACCCGGACACAAGAGAACCCTATCCGACCCTCCCAGCCCACTACCTCATGGGCCC CCAAACAAAGGCGCAGTTCCTTGGGGTAACGATGGGGGTCCATCCTCTTCAAGTAAGACTACAAACAAGTTTGAGGGACTATCCCAGCAG TCGAGCACCAGTTCTGCAAAGACTGCCCTTGGCCCAAGAGTTCTTCCTAAACTACCTCAGAAAGTGGCACTAAGGAAAACAGATCATCTC TCCCTAGACAAAGCCACCATCCCGCCCGAAATCTTTCAGAAATCATCACAGTTGGCAGAGTTGCCACAAAAGCCACCACCTGGAGACCTG CCCCCAAAGCCCACAGAACTGGCCCCCAAGCCCCAAATTGGAGATTTGCCGCCTAAGCCAGGAGAACTGCCCCCCAAACCACAGCTGGGG GACCTGCCACCCAAACCCCAACTCTCAGACTTACCTCCCAAACCACAGATGAAGGACCTGCCCCCCAAACCACAGCTGGGAGACCTGCTA GCAAAATCCCAGACTGGAGATGTCTCACCCAAGGCTCAGCAACCCTCTGAGGTCACACTGAAGTCACACCCATTGGATCTATCCCCAAAT GTGCAGTCCAGAGACGCCATCCAAAAGCAAGCATCTGAAGACTCCAACGACCTCACGCCTACTCTGCCAGAGACGCCCGTACCACTGCCC AGAAAAATCAATACGGGGAAAAATAAAGTGAGGCGAGTGAAGACCATTTATGACTGCCAGGCAGACAACGATGACGAGCTCACATTCATC GAGGGAGAAGTGATTATCGTCACAGGGGAAGAGGACCAGGAGTGGTGGATTGGCCACATCGAAGGACAGCCTGAAAGGAAGGGGGTCTTT CCAGTGTCCTTTGTTCATATCCTGTCTGACTAGCAAAACGCAGAACCTTAAGATTGTCCACATCCTTCATGCAAGACTGCTGCCTTCATG TAACCCTGGGCACAGTGTGTATATAGCTGCTGTTACAGAGTAAGAAACTCATGGAAGGGCCACCTCAGGAGGGGGATATAATGTGTGTTG TAAATATCCTGTGGTTTTCTGCCTTCACCAGTATGAGGGTAGCCTCGGACCCGGCGCGCCTTACTGGTTTGCCAAAGCCATCCTTGGCAT CTAGCACTTACATCTCTCTATGCTGTTCTACAAGCAAACAAACAAAAATAGGAGTATAGGAACTGCTGGCTTTGCAAATAGAAGTGGTCT CCAGCAACCGTTGAAAGGCATAGAATTGACTCTGTTCCTAACAATGCAGTATTCTCAATTGTGTTACTGAAAATGCAACATTAGCAAAGA GGTGGGTTCTGTTTTCCAGGTGAAACTTTTAGCTCCATGACAGACCAGCCTGTAGTTATCTGTGTACACAGTTTACAGCTACAAAAACCT ACTTTGGTATTTATTACAGAAAAGTGCTCAGTTAAATGTAAGTGTTATTCCTTCAGCAAAATATTCACTGACCCAAAACTCTTTATGGCA TTTTACAATGCACACAGCCTCATGCAAGTTTAGACAAGTGGATTTATACTGTCTTATGAGTGCCCGCCCCTGATATATTACCTCATTATG CAAAAATAACATATCTTTCATGACTATTTTGACAAAAGTTTAAAACACATATGAAGTTCAAATTTCAGGAACCAAGGACTGCCAGAAAAT ATTAGCCTCTACATTACGCATGCATTTAGAAGCTTACCTGAAATCTGCCTTTTATAAAGGAATAGTATGGATAAGTGGAATTGTACATTT TTTAAACTTGATTGCCATTAAAGCAGAAATTATAAGGTTGCAACAATATTTGTTTCTAATCACTGGCTTTCTCAAGAGTATGGATTGACA TATTGTGTTATGAATGCACATCTCTCAGATGTGTTGAAGCATCCATTGCATCCATTTTTTATTATTTTCTTAGTTTTGTTCTTGGACAAA TTTAAACTTTTAAAAGATTATTCAAGATGAATTTAAAAGTCAACCCTTCACACAGTTTCCCTACTGTATGTAGAATCCAGGTGCTGAAAC CAAGTGTTTCTTTTCCCATGCTCTTTGTTAAACCCCAATTATAGATAATTTTTCCAGTCTTAAGCTCTGTCCACCTTCAAGTCAATTCAT AACCAAGTTTTTGAACGCTGCTATGAATTGCACTGTGAAAAGCACTCTTCCCTCTCAGTTTTCTTTTCATCCCAGCCATGTTTATCAGAT CCTTAAGAACATTGTATTTCAGTCTTTTACATCAGTCTGAATTTTGGAAAAGAATGCAATAGTTGTACTCCACAGTCAGTGGAACTGTTC CCTGAGTCCGAGGCTCATGTGTCATTCTGGCACTACATTTGCTTAAATTGCTATTTTGGCAACAGCACAGAAAACTAATATTTTTAAGCA GAGAATCTTGGCAATGAGTGAGAGATGTTAATTTCACAGAAGCACAACTCCCAACCCAACCCTTAGGAAAAGCCCTCTTCCATCGTTACA GTGCTCAGTGAATATTAATTTAGTTCTGCTTAAGTGGTTGCTATACAAACTTTGAATAGCCACCTAATAAATAAACCTTGCATGACAAAC CTGCAAAATATTTTATCAGCTGTTATTGGAAAGTGATTTTAAGCAATTGCTTCCTCAGTGTCAGGGCACATGTGAATTTCCACACCAAAC AGAGCATGAGGAACCAGTTGACATGCTGGGTTGTGACTGGCAGCTTTAGCAGCCTCGGTACTGAAGCCACACCAGTGTCCGGATGGAAGT CTGCATCTGAGGTTGCTCAGTGTCCCGGTCATTCATTTACACATTTTAACTTGCATTAAAGAGCTGTTCTTTTCTGTGGCCTAGACTCTT TTCACTGATCTCAAAATAAACTGGTTTTTTTCAAAAAAAAAAAAAAAACAAAAACAAAAAAAAAACACAAAAGCTGCATGTCTAAAATTA CATGGAGTTAGTGTCTATTCTTTTTCCCCTTTTGCAGCAACTTACACAGCATTTTTAACACCTTTTTTTTCTAGTTTTTTTGTTCGGTTT TGTTTTCCATCAGGAATTTGAGTTCTCTCTAACCCAGCTTACTGTGGGACATAGGAAAACTCAGTAGAAATACCTTTGGTGATCTTGTTG AGTTTAAGTCTGATCTTGATCTTAAACTCAGTAAGCCACTATCTGCAATTTTGTACATTATATAGTATTTTGAAGATATGGAACCTTATG AAAAAAAAATAGCAAATTAGTTCTTTTTCCCCCAGAGGGGAAAGTTATGTTCTGCAAATAGTGTGTGTCTTATTTTACTGTTGAACAGCA ATTGCTATTTATTTTTTTATTGCCTAGAACTTCAACATGTTGTATAGGAATCCTGTAGTGCCACTAGTTAAATGCCGAATTCTCATCTGG ATGTTACCATCAAACATCAGTACACTTGTCATTTCACATGTGTTTAATGTGACAGTTTTTCAGTACTGTATGTGTTAATTTCTACTTTTT >In-frame_SSH2_ENST00000540801_chr17_28256956_-_ASAP1_ENST00000357668_chr8_131414216_-_6198nt CCGCACCCCTTTCCCCATCCCGGCTCCGTCACCCTCCCGTCCCCCACACTCAGGACAAGAATGCCCTGCCCGGAACAACCCAGCAGCGCC TAGATGGCTTTGGTCACGGTCCAGCGGTCACCTACCCCCAGCACCACCTCCAGCCCCTGCGCCTCGGGTCGTTTTCTGATGTGACGGCTG AGACATGAGATCTTCAGCCTCCAGGCTCTCCAGTTTTTCGTCGAGAGATTCACTATGGAATCGGATGCCGGACCAGATCTCTGTCTCGGA GTTCATCGCCGAGACCACCGAGGACTACAACTCGCCCACCACGTCCAGCTTCACCACGCGGCTGCACAACTGCAGGAACACCGTCACGCT GCTGGAGGAGGCTCTAGACCAAGATAGAACAGCCCTTCAGAAAGTGAAGAAGTCTGTAAAAGCAATATATAATTCTGGTCAAGATCATGT ACAAAATGAAGAAAACTATGCACAAGTTCTTGATAAGTTTGGGAGTAATTTTTTAAGTCGAGACAACCCCGACCTTGGCACCGCGTTTGT CAAGTTTTCTACTCTTACAAAGGAACTGTCCACACTGCTGAAAAATCTGCTCCAGGGTTTGAGCCACAATGTGATCTTCACCTTGGATTC TTTGTTAAAAGGAGACCTAAAGGGAGTCAAAGGAGATCTCAAGAAGCCATTTGACAAAGCCTGGAAAGATTATGAGACAAAGTTTACAAA AATTGAGAAAGAGAAAAGAGAGCACGCAAAACAACATGGGATGATCCGCACAGAGATAACAGGAGCTGAGATTGCGGAAGAAATGGAGAA GGAAAGGCGCCTCTTTCAGCTCCAAATGTGTGAATATCTCATTAAAGTTAATGAAATCAAGACCAAAAAGGGTGTGGATCTGCTGCAGAA TCTTATAAAGTATTACCATGCACAGTGCAATTTCTTTCAAGATGGCTTGAAAACAGCTGATAAGTTGAAACAGTACATTGAAAAACTGGC TGCTGATTTATATAATATAAAACAGACCCAGGATGAAGAAAAGAAACAGCTAACTGCACTCCGAGACTTAATAAAATCCTCTCTTCAACT GGATCAGAAAGAAGATTCTCAGAGCCGGCAAGGAGGATACAGCATGCATCAGCTCCAGGGCAATAAGGAATATGGCAGTGAAAAGAAGGG GTACCTGCTAAAGAAAAGTGACGGGATCCGGAAAGTATGGCAGAGGAGGAAGTGTTCAGTCAAGAATGGGATTCTGACCATCTCACATGC CACATCTAACAGGCAACCAGCCAAGTTGAACCTTCTCACCTGCCAAGTAAAACCTAATGCCGAAGACAAAAAATCTTTTGACCTGATATC ACATAATAGAACATATCACTTTCAGGCAGAAGATGAGCAGGATTATGTAGCATGGATATCAGTATTGACAAATAGCAAAGAAGAGGCCCT AACCATGGCCTTCCGTGGAGAGCAGAGTGCGGGAGAGAACAGCCTGGAAGACCTGACAAAAGCCATTATTGAGGATGTCCAGCGGCTCCC AGGGAATGACATTTGCTGCGATTGTGGCTCATCAGAACCCACCTGGCTTTCAACCAACTTGGGTATTTTGACCTGTATAGAATGTTCTGG CATCCATAGGGAAATGGGGGTTCATATTTCTCGCATTCAGTCTTTGGAACTAGACAAATTAGGAACTTCTGAACTCTTGCTGGCCAAGAA TGTAGGAAACAATAGTTTTAATGATATTATGGAAGCAAATTTACCCAGCCCCTCACCAAAACCCACCCCTTCAAGTGATATGACTGTACG AAAAGAATATATCACTGCAAAGTATGTAGATCATAGGTTTTCAAGGAAGACCTGTTCAACTTCATCAGCTAAACTAAATGAATTGCTTGA GGCCATCAAATCCAGGGATTTACTTGCACTAATTCAAGTCTATGCAGAAGGGGTAGAGCTAATGGAACCACTGCTGGAACCTGGGCAGGA GCTTGGGGAGACAGCCCTTCACCTTGCCGTCCGAACTGCAGATCAGACATCTCTCCATTTGGTTGACTTCCTTGTACAAAACTGTGGGAA CCTGGATAAGCAGACGGCCCTGGGAAACACAGTTCTACACTACTGTAGTATGTACAGTAAACCTGAGTGTTTGAAGCTTTTGCTCAGGAG CAAGCCCACTGTGGATATAGTTAACCAGGCTGGAGAAACTGCCCTAGACATAGCAAAGAGACTAAAAGCTACCCAGTGTGAAGATCTGCT TTCCCAGGCTAAATCTGGAAAGTTCAATCCACACGTCCACGTAGAATATGAGTGGAATCTTCGACAGGAGGAGATAGATGAGAGCGATGA TGATCTGGATGACAAACCAAGCCCTATCAAGAAAGAGCGCTCACCCAGACCTCAGAGCTTCTGCCACTCCTCCAGCATCTCCCCCCAGGA CAAGCTGGCACTGCCAGGATTCAGCACTCCAAGGGACAAACAGCGGCTCTCCTATGGAGCCTTCACCAACCAGATCTTCGTTTCCACAAG CACAGACTCGCCCACATCACCAACCACGGAGGCTCCCCCTCTGCCTCCTAGGAACGCCGGGAAAGGTCCAACTGGCCCACCTTCAACACT CCCTCTAAGCACCCAGACCTCTAGTGGCAGCTCCACCCTATCCAAGAAGAGGCCTCCTCCCCCACCACCCGGACACAAGAGAACCCTATC CGACCCTCCCAGCCCACTACCTCATGGGCCCCCAAACAAAGGCGCAGTTCCTTGGGGTAACGATGGGGGTCCATCCTCTTCAAGTAAGAC TACAAACAAGTTTGAGGGACTATCCCAGCAGTCGAGCACCAGTTCTGCAAAGACTGCCCTTGGCCCAAGAGTTCTTCCTAAACTACCTCA GAAAGTGGCACTAAGGAAAACAGATCATCTCTCCCTAGACAAAGCCACCATCCCGCCCGAAATCTTTCAGAAATCATCACAGTTGGCAGA GTTGCCACAAAAGCCACCACCTGGAGACCTGCCCCCAAAGCCCACAGAACTGGCCCCCAAGCCCCAAATTGGAGATTTGCCGCCTAAGCC AGGAGAACTGCCCCCCAAACCACAGCTGGGGGACCTGCCACCCAAACCCCAACTCTCAGACTTACCTCCCAAACCACAGATGAAGGACCT GCCCCCCAAACCACAGCTGGGAGACCTGCTAGCAAAATCCCAGACTGGAGATGTCTCACCCAAGGCTCAGCAACCCTCTGAGGTCACACT GAAGTCACACCCATTGGATCTATCCCCAAATGTGCAGTCCAGAGACGCCATCCAAAAGCAAGCATCTGAAGACTCCAACGACCTCACGCC TACTCTGCCAGAGACGCCCGTACCACTGCCCAGAAAAATCAATACGGGGAAAAATAAAGTGAGGCGAGTGAAGACCATTTATGACTGCCA GGCAGACAACGATGACGAGCTCACATTCATCGAGGGAGAAGTGATTATCGTCACAGGGGAAGAGGACCAGGAGTGGTGGATTGGCCACAT CGAAGGACAGCCTGAAAGGAAGGGGGTCTTTCCAGTGTCCTTTGTTCATATCCTGTCTGACTAGCAAAACGCAGAACCTTAAGATTGTCC ACATCCTTCATGCAAGACTGCTGCCTTCATGTAACCCTGGGCACAGTGTGTATATAGCTGCTGTTACAGAGTAAGAAACTCATGGAAGGG CCACCTCAGGAGGGGGATATAATGTGTGTTGTAAATATCCTGTGGTTTTCTGCCTTCACCAGTATGAGGGTAGCCTCGGACCCGGCGCGC CTTACTGGTTTGCCAAAGCCATCCTTGGCATCTAGCACTTACATCTCTCTATGCTGTTCTACAAGCAAACAAACAAAAATAGGAGTATAG GAACTGCTGGCTTTGCAAATAGAAGTGGTCTCCAGCAACCGTTGAAAGGCATAGAATTGACTCTGTTCCTAACAATGCAGTATTCTCAAT TGTGTTACTGAAAATGCAACATTAGCAAAGAGGTGGGTTCTGTTTTCCAGGTGAAACTTTTAGCTCCATGACAGACCAGCCTGTAGTTAT CTGTGTACACAGTTTACAGCTACAAAAACCTACTTTGGTATTTATTACAGAAAAGTGCTCAGTTAAATGTAAGTGTTATTCCTTCAGCAA AATATTCACTGACCCAAAACTCTTTATGGCATTTTACAATGCACACAGCCTCATGCAAGTTTAGACAAGTGGATTTATACTGTCTTATGA GTGCCCGCCCCTGATATATTACCTCATTATGCAAAAATAACATATCTTTCATGACTATTTTGACAAAAGTTTAAAACACATATGAAGTTC AAATTTCAGGAACCAAGGACTGCCAGAAAATATTAGCCTCTACATTACGCATGCATTTAGAAGCTTACCTGAAATCTGCCTTTTATAAAG GAATAGTATGGATAAGTGGAATTGTACATTTTTTAAACTTGATTGCCATTAAAGCAGAAATTATAAGGTTGCAACAATATTTGTTTCTAA TCACTGGCTTTCTCAAGAGTATGGATTGACATATTGTGTTATGAATGCACATCTCTCAGATGTGTTGAAGCATCCATTGCATCCATTTTT TATTATTTTCTTAGTTTTGTTCTTGGACAAATTTAAACTTTTAAAAGATTATTCAAGATGAATTTAAAAGTCAACCCTTCACACAGTTTC CCTACTGTATGTAGAATCCAGGTGCTGAAACCAAGTGTTTCTTTTCCCATGCTCTTTGTTAAACCCCAATTATAGATAATTTTTCCAGTC TTAAGCTCTGTCCACCTTCAAGTCAATTCATAACCAAGTTTTTGAACGCTGCTATGAATTGCACTGTGAAAAGCACTCTTCCCTCTCAGT TTTCTTTTCATCCCAGCCATGTTTATCAGATCCTTAAGAACATTGTATTTCAGTCTTTTACATCAGTCTGAATTTTGGAAAAGAATGCAA TAGTTGTACTCCACAGTCAGTGGAACTGTTCCCTGAGTCCGAGGCTCATGTGTCATTCTGGCACTACATTTGCTTAAATTGCTATTTTGG CAACAGCACAGAAAACTAATATTTTTAAGCAGAGAATCTTGGCAATGAGTGAGAGATGTTAATTTCACAGAAGCACAACTCCCAACCCAA CCCTTAGGAAAAGCCCTCTTCCATCGTTACAGTGCTCAGTGAATATTAATTTAGTTCTGCTTAAGTGGTTGCTATACAAACTTTGAATAG CCACCTAATAAATAAACCTTGCATGACAAACCTGCAAAATATTTTATCAGCTGTTATTGGAAAGTGATTTTAAGCAATTGCTTCCTCAGT GTCAGGGCACATGTGAATTTCCACACCAAACAGAGCATGAGGAACCAGTTGACATGCTGGGTTGTGACTGGCAGCTTTAGCAGCCTCGGT ACTGAAGCCACACCAGTGTCCGGATGGAAGTCTGCATCTGAGGTTGCTCAGTGTCCCGGTCATTCATTTACACATTTTAACTTGCATTAA AGAGCTGTTCTTTTCTGTGGCCTAGACTCTTTTCACTGATCTCAAAATAAACTGGTTTTTTTCAAAAAAAAAAAAAAAACAAAAACAAAA AAAAAACACAAAAGCTGCATGTCTAAAATTACATGGAGTTAGTGTCTATTCTTTTTCCCCTTTTGCAGCAACTTACACAGCATTTTTAAC ACCTTTTTTTTCTAGTTTTTTTGTTCGGTTTTGTTTTCCATCAGGAATTTGAGTTCTCTCTAACCCAGCTTACTGTGGGACATAGGAAAA CTCAGTAGAAATACCTTTGGTGATCTTGTTGAGTTTAAGTCTGATCTTGATCTTAAACTCAGTAAGCCACTATCTGCAATTTTGTACATT ATATAGTATTTTGAAGATATGGAACCTTATGAAAAAAAAATAGCAAATTAGTTCTTTTTCCCCCAGAGGGGAAAGTTATGTTCTGCAAAT AGTGTGTGTCTTATTTTACTGTTGAACAGCAATTGCTATTTATTTTTTTATTGCCTAGAACTTCAACATGTTGTATAGGAATCCTGTAGT GCCACTAGTTAAATGCCGAATTCTCATCTGGATGTTACCATCAAACATCAGTACACTTGTCATTTCACATGTGTTTAATGTGACAGTTTT >In-frame_SSH2_ENST00000590153_chr17_28256956_-_ASAP1_ENST00000357668_chr8_131414216_-_6333nt ATTGTGCCCCGCAGCTGCGGAACCGCCCGCCCGCCGCCCGTTCGGAGCGTCAGTCGGCGACAGTCTGGTGGTGGGTGCGGAGTCTGCGGC CGTTCCCGCGGCCTCCTCCTCCTCCCCGTTCCCTTCACCCCCACCCCGCACCCCTTTCCCCATCCCGGCTCCGTCACCCTCCCGTCCCCC ACACTCAGGACAAGAATGCCCTGCCCGGAACAACCCAGCAGCGCCTAGATGGCTTTGGTCACGGTCCAGCGGTCACCTACCCCCAGCACC ACCTCCAGCCCCTGCGCCTCGGGTCGTTTTCTGATGTGACGGCTGAGACATGAGATCTTCAGCCTCCAGGCTCTCCAGTTTTTCGTCGAG AGATTCACTATGGAATCGGATGCCGGACCAGATCTCTGTCTCGGAGTTCATCGCCGAGACCACCGAGGACTACAACTCGCCCACCACGTC CAGCTTCACCACGCGGCTGCACAACTGCAGGAACACCGTCACGCTGCTGGAGGAGGCTCTAGACCAAGATAGAACAGCCCTTCAGAAAGT GAAGAAGTCTGTAAAAGCAATATATAATTCTGGTCAAGATCATGTACAAAATGAAGAAAACTATGCACAAGTTCTTGATAAGTTTGGGAG TAATTTTTTAAGTCGAGACAACCCCGACCTTGGCACCGCGTTTGTCAAGTTTTCTACTCTTACAAAGGAACTGTCCACACTGCTGAAAAA TCTGCTCCAGGGTTTGAGCCACAATGTGATCTTCACCTTGGATTCTTTGTTAAAAGGAGACCTAAAGGGAGTCAAAGGAGATCTCAAGAA GCCATTTGACAAAGCCTGGAAAGATTATGAGACAAAGTTTACAAAAATTGAGAAAGAGAAAAGAGAGCACGCAAAACAACATGGGATGAT CCGCACAGAGATAACAGGAGCTGAGATTGCGGAAGAAATGGAGAAGGAAAGGCGCCTCTTTCAGCTCCAAATGTGTGAATATCTCATTAA AGTTAATGAAATCAAGACCAAAAAGGGTGTGGATCTGCTGCAGAATCTTATAAAGTATTACCATGCACAGTGCAATTTCTTTCAAGATGG CTTGAAAACAGCTGATAAGTTGAAACAGTACATTGAAAAACTGGCTGCTGATTTATATAATATAAAACAGACCCAGGATGAAGAAAAGAA ACAGCTAACTGCACTCCGAGACTTAATAAAATCCTCTCTTCAACTGGATCAGAAAGAAGATTCTCAGAGCCGGCAAGGAGGATACAGCAT GCATCAGCTCCAGGGCAATAAGGAATATGGCAGTGAAAAGAAGGGGTACCTGCTAAAGAAAAGTGACGGGATCCGGAAAGTATGGCAGAG GAGGAAGTGTTCAGTCAAGAATGGGATTCTGACCATCTCACATGCCACATCTAACAGGCAACCAGCCAAGTTGAACCTTCTCACCTGCCA AGTAAAACCTAATGCCGAAGACAAAAAATCTTTTGACCTGATATCACATAATAGAACATATCACTTTCAGGCAGAAGATGAGCAGGATTA TGTAGCATGGATATCAGTATTGACAAATAGCAAAGAAGAGGCCCTAACCATGGCCTTCCGTGGAGAGCAGAGTGCGGGAGAGAACAGCCT GGAAGACCTGACAAAAGCCATTATTGAGGATGTCCAGCGGCTCCCAGGGAATGACATTTGCTGCGATTGTGGCTCATCAGAACCCACCTG GCTTTCAACCAACTTGGGTATTTTGACCTGTATAGAATGTTCTGGCATCCATAGGGAAATGGGGGTTCATATTTCTCGCATTCAGTCTTT GGAACTAGACAAATTAGGAACTTCTGAACTCTTGCTGGCCAAGAATGTAGGAAACAATAGTTTTAATGATATTATGGAAGCAAATTTACC CAGCCCCTCACCAAAACCCACCCCTTCAAGTGATATGACTGTACGAAAAGAATATATCACTGCAAAGTATGTAGATCATAGGTTTTCAAG GAAGACCTGTTCAACTTCATCAGCTAAACTAAATGAATTGCTTGAGGCCATCAAATCCAGGGATTTACTTGCACTAATTCAAGTCTATGC AGAAGGGGTAGAGCTAATGGAACCACTGCTGGAACCTGGGCAGGAGCTTGGGGAGACAGCCCTTCACCTTGCCGTCCGAACTGCAGATCA GACATCTCTCCATTTGGTTGACTTCCTTGTACAAAACTGTGGGAACCTGGATAAGCAGACGGCCCTGGGAAACACAGTTCTACACTACTG TAGTATGTACAGTAAACCTGAGTGTTTGAAGCTTTTGCTCAGGAGCAAGCCCACTGTGGATATAGTTAACCAGGCTGGAGAAACTGCCCT AGACATAGCAAAGAGACTAAAAGCTACCCAGTGTGAAGATCTGCTTTCCCAGGCTAAATCTGGAAAGTTCAATCCACACGTCCACGTAGA ATATGAGTGGAATCTTCGACAGGAGGAGATAGATGAGAGCGATGATGATCTGGATGACAAACCAAGCCCTATCAAGAAAGAGCGCTCACC CAGACCTCAGAGCTTCTGCCACTCCTCCAGCATCTCCCCCCAGGACAAGCTGGCACTGCCAGGATTCAGCACTCCAAGGGACAAACAGCG GCTCTCCTATGGAGCCTTCACCAACCAGATCTTCGTTTCCACAAGCACAGACTCGCCCACATCACCAACCACGGAGGCTCCCCCTCTGCC TCCTAGGAACGCCGGGAAAGGTCCAACTGGCCCACCTTCAACACTCCCTCTAAGCACCCAGACCTCTAGTGGCAGCTCCACCCTATCCAA GAAGAGGCCTCCTCCCCCACCACCCGGACACAAGAGAACCCTATCCGACCCTCCCAGCCCACTACCTCATGGGCCCCCAAACAAAGGCGC AGTTCCTTGGGGTAACGATGGGGGTCCATCCTCTTCAAGTAAGACTACAAACAAGTTTGAGGGACTATCCCAGCAGTCGAGCACCAGTTC TGCAAAGACTGCCCTTGGCCCAAGAGTTCTTCCTAAACTACCTCAGAAAGTGGCACTAAGGAAAACAGATCATCTCTCCCTAGACAAAGC CACCATCCCGCCCGAAATCTTTCAGAAATCATCACAGTTGGCAGAGTTGCCACAAAAGCCACCACCTGGAGACCTGCCCCCAAAGCCCAC AGAACTGGCCCCCAAGCCCCAAATTGGAGATTTGCCGCCTAAGCCAGGAGAACTGCCCCCCAAACCACAGCTGGGGGACCTGCCACCCAA ACCCCAACTCTCAGACTTACCTCCCAAACCACAGATGAAGGACCTGCCCCCCAAACCACAGCTGGGAGACCTGCTAGCAAAATCCCAGAC TGGAGATGTCTCACCCAAGGCTCAGCAACCCTCTGAGGTCACACTGAAGTCACACCCATTGGATCTATCCCCAAATGTGCAGTCCAGAGA CGCCATCCAAAAGCAAGCATCTGAAGACTCCAACGACCTCACGCCTACTCTGCCAGAGACGCCCGTACCACTGCCCAGAAAAATCAATAC GGGGAAAAATAAAGTGAGGCGAGTGAAGACCATTTATGACTGCCAGGCAGACAACGATGACGAGCTCACATTCATCGAGGGAGAAGTGAT TATCGTCACAGGGGAAGAGGACCAGGAGTGGTGGATTGGCCACATCGAAGGACAGCCTGAAAGGAAGGGGGTCTTTCCAGTGTCCTTTGT TCATATCCTGTCTGACTAGCAAAACGCAGAACCTTAAGATTGTCCACATCCTTCATGCAAGACTGCTGCCTTCATGTAACCCTGGGCACA GTGTGTATATAGCTGCTGTTACAGAGTAAGAAACTCATGGAAGGGCCACCTCAGGAGGGGGATATAATGTGTGTTGTAAATATCCTGTGG TTTTCTGCCTTCACCAGTATGAGGGTAGCCTCGGACCCGGCGCGCCTTACTGGTTTGCCAAAGCCATCCTTGGCATCTAGCACTTACATC TCTCTATGCTGTTCTACAAGCAAACAAACAAAAATAGGAGTATAGGAACTGCTGGCTTTGCAAATAGAAGTGGTCTCCAGCAACCGTTGA AAGGCATAGAATTGACTCTGTTCCTAACAATGCAGTATTCTCAATTGTGTTACTGAAAATGCAACATTAGCAAAGAGGTGGGTTCTGTTT TCCAGGTGAAACTTTTAGCTCCATGACAGACCAGCCTGTAGTTATCTGTGTACACAGTTTACAGCTACAAAAACCTACTTTGGTATTTAT TACAGAAAAGTGCTCAGTTAAATGTAAGTGTTATTCCTTCAGCAAAATATTCACTGACCCAAAACTCTTTATGGCATTTTACAATGCACA CAGCCTCATGCAAGTTTAGACAAGTGGATTTATACTGTCTTATGAGTGCCCGCCCCTGATATATTACCTCATTATGCAAAAATAACATAT CTTTCATGACTATTTTGACAAAAGTTTAAAACACATATGAAGTTCAAATTTCAGGAACCAAGGACTGCCAGAAAATATTAGCCTCTACAT TACGCATGCATTTAGAAGCTTACCTGAAATCTGCCTTTTATAAAGGAATAGTATGGATAAGTGGAATTGTACATTTTTTAAACTTGATTG CCATTAAAGCAGAAATTATAAGGTTGCAACAATATTTGTTTCTAATCACTGGCTTTCTCAAGAGTATGGATTGACATATTGTGTTATGAA TGCACATCTCTCAGATGTGTTGAAGCATCCATTGCATCCATTTTTTATTATTTTCTTAGTTTTGTTCTTGGACAAATTTAAACTTTTAAA AGATTATTCAAGATGAATTTAAAAGTCAACCCTTCACACAGTTTCCCTACTGTATGTAGAATCCAGGTGCTGAAACCAAGTGTTTCTTTT CCCATGCTCTTTGTTAAACCCCAATTATAGATAATTTTTCCAGTCTTAAGCTCTGTCCACCTTCAAGTCAATTCATAACCAAGTTTTTGA ACGCTGCTATGAATTGCACTGTGAAAAGCACTCTTCCCTCTCAGTTTTCTTTTCATCCCAGCCATGTTTATCAGATCCTTAAGAACATTG TATTTCAGTCTTTTACATCAGTCTGAATTTTGGAAAAGAATGCAATAGTTGTACTCCACAGTCAGTGGAACTGTTCCCTGAGTCCGAGGC TCATGTGTCATTCTGGCACTACATTTGCTTAAATTGCTATTTTGGCAACAGCACAGAAAACTAATATTTTTAAGCAGAGAATCTTGGCAA TGAGTGAGAGATGTTAATTTCACAGAAGCACAACTCCCAACCCAACCCTTAGGAAAAGCCCTCTTCCATCGTTACAGTGCTCAGTGAATA TTAATTTAGTTCTGCTTAAGTGGTTGCTATACAAACTTTGAATAGCCACCTAATAAATAAACCTTGCATGACAAACCTGCAAAATATTTT ATCAGCTGTTATTGGAAAGTGATTTTAAGCAATTGCTTCCTCAGTGTCAGGGCACATGTGAATTTCCACACCAAACAGAGCATGAGGAAC CAGTTGACATGCTGGGTTGTGACTGGCAGCTTTAGCAGCCTCGGTACTGAAGCCACACCAGTGTCCGGATGGAAGTCTGCATCTGAGGTT GCTCAGTGTCCCGGTCATTCATTTACACATTTTAACTTGCATTAAAGAGCTGTTCTTTTCTGTGGCCTAGACTCTTTTCACTGATCTCAA AATAAACTGGTTTTTTTCAAAAAAAAAAAAAAAACAAAAACAAAAAAAAAACACAAAAGCTGCATGTCTAAAATTACATGGAGTTAGTGT CTATTCTTTTTCCCCTTTTGCAGCAACTTACACAGCATTTTTAACACCTTTTTTTTCTAGTTTTTTTGTTCGGTTTTGTTTTCCATCAGG AATTTGAGTTCTCTCTAACCCAGCTTACTGTGGGACATAGGAAAACTCAGTAGAAATACCTTTGGTGATCTTGTTGAGTTTAAGTCTGAT CTTGATCTTAAACTCAGTAAGCCACTATCTGCAATTTTGTACATTATATAGTATTTTGAAGATATGGAACCTTATGAAAAAAAAATAGCA AATTAGTTCTTTTTCCCCCAGAGGGGAAAGTTATGTTCTGCAAATAGTGTGTGTCTTATTTTACTGTTGAACAGCAATTGCTATTTATTT TTTTATTGCCTAGAACTTCAACATGTTGTATAGGAATCCTGTAGTGCCACTAGTTAAATGCCGAATTCTCATCTGGATGTTACCATCAAA CATCAGTACACTTGTCATTTCACATGTGTTTAATGTGACAGTTTTTCAGTACTGTATGTGTTAATTTCTACTTTTTTTAATATTTAAAAT >In-frame_SSH2_ENST00000579954_chr17_28256956_-_ASAP1_ENST00000357668_chr8_131414216_-_6167nt CCCTCCCGTCCCCCACACTCAGGACAAGAATGCCCTGCCCGGAACAACCCAGCAGCGCCTAGATGGCTTTGGTCACGGTCCAGCGGTCAC CTACCCCCAGCACCACCTCCAGCCCCTGCGCCTCGGGTCGTTTTCTGATGTGACGGCTGAGACATGAGATCTTCAGCCTCCAGGCTCTCC AGTTTTTCGTCGAGAGATTCACTATGGAATCGGATGCCGGACCAGATCTCTGTCTCGGAGTTCATCGCCGAGACCACCGAGGACTACAAC TCGCCCACCACGTCCAGCTTCACCACGCGGCTGCACAACTGCAGGAACACCGTCACGCTGCTGGAGGAGGCTCTAGACCAAGATAGAACA GCCCTTCAGAAAGTGAAGAAGTCTGTAAAAGCAATATATAATTCTGGTCAAGATCATGTACAAAATGAAGAAAACTATGCACAAGTTCTT GATAAGTTTGGGAGTAATTTTTTAAGTCGAGACAACCCCGACCTTGGCACCGCGTTTGTCAAGTTTTCTACTCTTACAAAGGAACTGTCC ACACTGCTGAAAAATCTGCTCCAGGGTTTGAGCCACAATGTGATCTTCACCTTGGATTCTTTGTTAAAAGGAGACCTAAAGGGAGTCAAA GGAGATCTCAAGAAGCCATTTGACAAAGCCTGGAAAGATTATGAGACAAAGTTTACAAAAATTGAGAAAGAGAAAAGAGAGCACGCAAAA CAACATGGGATGATCCGCACAGAGATAACAGGAGCTGAGATTGCGGAAGAAATGGAGAAGGAAAGGCGCCTCTTTCAGCTCCAAATGTGT GAATATCTCATTAAAGTTAATGAAATCAAGACCAAAAAGGGTGTGGATCTGCTGCAGAATCTTATAAAGTATTACCATGCACAGTGCAAT TTCTTTCAAGATGGCTTGAAAACAGCTGATAAGTTGAAACAGTACATTGAAAAACTGGCTGCTGATTTATATAATATAAAACAGACCCAG GATGAAGAAAAGAAACAGCTAACTGCACTCCGAGACTTAATAAAATCCTCTCTTCAACTGGATCAGAAAGAAGATTCTCAGAGCCGGCAA GGAGGATACAGCATGCATCAGCTCCAGGGCAATAAGGAATATGGCAGTGAAAAGAAGGGGTACCTGCTAAAGAAAAGTGACGGGATCCGG AAAGTATGGCAGAGGAGGAAGTGTTCAGTCAAGAATGGGATTCTGACCATCTCACATGCCACATCTAACAGGCAACCAGCCAAGTTGAAC CTTCTCACCTGCCAAGTAAAACCTAATGCCGAAGACAAAAAATCTTTTGACCTGATATCACATAATAGAACATATCACTTTCAGGCAGAA GATGAGCAGGATTATGTAGCATGGATATCAGTATTGACAAATAGCAAAGAAGAGGCCCTAACCATGGCCTTCCGTGGAGAGCAGAGTGCG GGAGAGAACAGCCTGGAAGACCTGACAAAAGCCATTATTGAGGATGTCCAGCGGCTCCCAGGGAATGACATTTGCTGCGATTGTGGCTCA TCAGAACCCACCTGGCTTTCAACCAACTTGGGTATTTTGACCTGTATAGAATGTTCTGGCATCCATAGGGAAATGGGGGTTCATATTTCT CGCATTCAGTCTTTGGAACTAGACAAATTAGGAACTTCTGAACTCTTGCTGGCCAAGAATGTAGGAAACAATAGTTTTAATGATATTATG GAAGCAAATTTACCCAGCCCCTCACCAAAACCCACCCCTTCAAGTGATATGACTGTACGAAAAGAATATATCACTGCAAAGTATGTAGAT CATAGGTTTTCAAGGAAGACCTGTTCAACTTCATCAGCTAAACTAAATGAATTGCTTGAGGCCATCAAATCCAGGGATTTACTTGCACTA ATTCAAGTCTATGCAGAAGGGGTAGAGCTAATGGAACCACTGCTGGAACCTGGGCAGGAGCTTGGGGAGACAGCCCTTCACCTTGCCGTC CGAACTGCAGATCAGACATCTCTCCATTTGGTTGACTTCCTTGTACAAAACTGTGGGAACCTGGATAAGCAGACGGCCCTGGGAAACACA GTTCTACACTACTGTAGTATGTACAGTAAACCTGAGTGTTTGAAGCTTTTGCTCAGGAGCAAGCCCACTGTGGATATAGTTAACCAGGCT GGAGAAACTGCCCTAGACATAGCAAAGAGACTAAAAGCTACCCAGTGTGAAGATCTGCTTTCCCAGGCTAAATCTGGAAAGTTCAATCCA CACGTCCACGTAGAATATGAGTGGAATCTTCGACAGGAGGAGATAGATGAGAGCGATGATGATCTGGATGACAAACCAAGCCCTATCAAG AAAGAGCGCTCACCCAGACCTCAGAGCTTCTGCCACTCCTCCAGCATCTCCCCCCAGGACAAGCTGGCACTGCCAGGATTCAGCACTCCA AGGGACAAACAGCGGCTCTCCTATGGAGCCTTCACCAACCAGATCTTCGTTTCCACAAGCACAGACTCGCCCACATCACCAACCACGGAG GCTCCCCCTCTGCCTCCTAGGAACGCCGGGAAAGGTCCAACTGGCCCACCTTCAACACTCCCTCTAAGCACCCAGACCTCTAGTGGCAGC TCCACCCTATCCAAGAAGAGGCCTCCTCCCCCACCACCCGGACACAAGAGAACCCTATCCGACCCTCCCAGCCCACTACCTCATGGGCCC CCAAACAAAGGCGCAGTTCCTTGGGGTAACGATGGGGGTCCATCCTCTTCAAGTAAGACTACAAACAAGTTTGAGGGACTATCCCAGCAG TCGAGCACCAGTTCTGCAAAGACTGCCCTTGGCCCAAGAGTTCTTCCTAAACTACCTCAGAAAGTGGCACTAAGGAAAACAGATCATCTC TCCCTAGACAAAGCCACCATCCCGCCCGAAATCTTTCAGAAATCATCACAGTTGGCAGAGTTGCCACAAAAGCCACCACCTGGAGACCTG CCCCCAAAGCCCACAGAACTGGCCCCCAAGCCCCAAATTGGAGATTTGCCGCCTAAGCCAGGAGAACTGCCCCCCAAACCACAGCTGGGG GACCTGCCACCCAAACCCCAACTCTCAGACTTACCTCCCAAACCACAGATGAAGGACCTGCCCCCCAAACCACAGCTGGGAGACCTGCTA GCAAAATCCCAGACTGGAGATGTCTCACCCAAGGCTCAGCAACCCTCTGAGGTCACACTGAAGTCACACCCATTGGATCTATCCCCAAAT GTGCAGTCCAGAGACGCCATCCAAAAGCAAGCATCTGAAGACTCCAACGACCTCACGCCTACTCTGCCAGAGACGCCCGTACCACTGCCC AGAAAAATCAATACGGGGAAAAATAAAGTGAGGCGAGTGAAGACCATTTATGACTGCCAGGCAGACAACGATGACGAGCTCACATTCATC GAGGGAGAAGTGATTATCGTCACAGGGGAAGAGGACCAGGAGTGGTGGATTGGCCACATCGAAGGACAGCCTGAAAGGAAGGGGGTCTTT CCAGTGTCCTTTGTTCATATCCTGTCTGACTAGCAAAACGCAGAACCTTAAGATTGTCCACATCCTTCATGCAAGACTGCTGCCTTCATG TAACCCTGGGCACAGTGTGTATATAGCTGCTGTTACAGAGTAAGAAACTCATGGAAGGGCCACCTCAGGAGGGGGATATAATGTGTGTTG TAAATATCCTGTGGTTTTCTGCCTTCACCAGTATGAGGGTAGCCTCGGACCCGGCGCGCCTTACTGGTTTGCCAAAGCCATCCTTGGCAT CTAGCACTTACATCTCTCTATGCTGTTCTACAAGCAAACAAACAAAAATAGGAGTATAGGAACTGCTGGCTTTGCAAATAGAAGTGGTCT CCAGCAACCGTTGAAAGGCATAGAATTGACTCTGTTCCTAACAATGCAGTATTCTCAATTGTGTTACTGAAAATGCAACATTAGCAAAGA GGTGGGTTCTGTTTTCCAGGTGAAACTTTTAGCTCCATGACAGACCAGCCTGTAGTTATCTGTGTACACAGTTTACAGCTACAAAAACCT ACTTTGGTATTTATTACAGAAAAGTGCTCAGTTAAATGTAAGTGTTATTCCTTCAGCAAAATATTCACTGACCCAAAACTCTTTATGGCA TTTTACAATGCACACAGCCTCATGCAAGTTTAGACAAGTGGATTTATACTGTCTTATGAGTGCCCGCCCCTGATATATTACCTCATTATG CAAAAATAACATATCTTTCATGACTATTTTGACAAAAGTTTAAAACACATATGAAGTTCAAATTTCAGGAACCAAGGACTGCCAGAAAAT ATTAGCCTCTACATTACGCATGCATTTAGAAGCTTACCTGAAATCTGCCTTTTATAAAGGAATAGTATGGATAAGTGGAATTGTACATTT TTTAAACTTGATTGCCATTAAAGCAGAAATTATAAGGTTGCAACAATATTTGTTTCTAATCACTGGCTTTCTCAAGAGTATGGATTGACA TATTGTGTTATGAATGCACATCTCTCAGATGTGTTGAAGCATCCATTGCATCCATTTTTTATTATTTTCTTAGTTTTGTTCTTGGACAAA TTTAAACTTTTAAAAGATTATTCAAGATGAATTTAAAAGTCAACCCTTCACACAGTTTCCCTACTGTATGTAGAATCCAGGTGCTGAAAC CAAGTGTTTCTTTTCCCATGCTCTTTGTTAAACCCCAATTATAGATAATTTTTCCAGTCTTAAGCTCTGTCCACCTTCAAGTCAATTCAT AACCAAGTTTTTGAACGCTGCTATGAATTGCACTGTGAAAAGCACTCTTCCCTCTCAGTTTTCTTTTCATCCCAGCCATGTTTATCAGAT CCTTAAGAACATTGTATTTCAGTCTTTTACATCAGTCTGAATTTTGGAAAAGAATGCAATAGTTGTACTCCACAGTCAGTGGAACTGTTC CCTGAGTCCGAGGCTCATGTGTCATTCTGGCACTACATTTGCTTAAATTGCTATTTTGGCAACAGCACAGAAAACTAATATTTTTAAGCA GAGAATCTTGGCAATGAGTGAGAGATGTTAATTTCACAGAAGCACAACTCCCAACCCAACCCTTAGGAAAAGCCCTCTTCCATCGTTACA GTGCTCAGTGAATATTAATTTAGTTCTGCTTAAGTGGTTGCTATACAAACTTTGAATAGCCACCTAATAAATAAACCTTGCATGACAAAC CTGCAAAATATTTTATCAGCTGTTATTGGAAAGTGATTTTAAGCAATTGCTTCCTCAGTGTCAGGGCACATGTGAATTTCCACACCAAAC AGAGCATGAGGAACCAGTTGACATGCTGGGTTGTGACTGGCAGCTTTAGCAGCCTCGGTACTGAAGCCACACCAGTGTCCGGATGGAAGT CTGCATCTGAGGTTGCTCAGTGTCCCGGTCATTCATTTACACATTTTAACTTGCATTAAAGAGCTGTTCTTTTCTGTGGCCTAGACTCTT TTCACTGATCTCAAAATAAACTGGTTTTTTTCAAAAAAAAAAAAAAAACAAAAACAAAAAAAAAACACAAAAGCTGCATGTCTAAAATTA CATGGAGTTAGTGTCTATTCTTTTTCCCCTTTTGCAGCAACTTACACAGCATTTTTAACACCTTTTTTTTCTAGTTTTTTTGTTCGGTTT TGTTTTCCATCAGGAATTTGAGTTCTCTCTAACCCAGCTTACTGTGGGACATAGGAAAACTCAGTAGAAATACCTTTGGTGATCTTGTTG AGTTTAAGTCTGATCTTGATCTTAAACTCAGTAAGCCACTATCTGCAATTTTGTACATTATATAGTATTTTGAAGATATGGAACCTTATG AAAAAAAAATAGCAAATTAGTTCTTTTTCCCCCAGAGGGGAAAGTTATGTTCTGCAAATAGTGTGTGTCTTATTTTACTGTTGAACAGCA ATTGCTATTTATTTTTTTATTGCCTAGAACTTCAACATGTTGTATAGGAATCCTGTAGTGCCACTAGTTAAATGCCGAATTCTCATCTGG ATGTTACCATCAAACATCAGTACACTTGTCATTTCACATGTGTTTAATGTGACAGTTTTTCAGTACTGTATGTGTTAATTTCTACTTTTT |
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FusionGenePPI for SSH2_ASAP1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SSH2 | ACTB, ELAVL1, BAG3, XPO1, CAPZA2, DBN1, FLNA, MYH9, PPP1CB, IQGAP1, KIF3A, SYNPO, LIMA1, ANLN, MYO19, MYO18A, GAN, FBXW7, MYO1D, TRIM25 | ASAP1 | SRC, CRK, PXN, PACSIN1, PACSIN2, PACSIN3, TRIP10, FCHSD1, GRB2, ARF6, ELAVL1, SH3KBP1, CBL, CBLB, ARAP3, CTTN, PTK2, LRRK1, NCK2, NTRK1, RAB11FIP3, RAB11FIP1, RAB11FIP2, CDH1, PTPN12, ASAP3, TRIM25, ARF1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SSH2_ASAP1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SSH2_ASAP1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ASAP1 | C0005695 | Bladder Neoplasm | 1 | CTD_human |
| Tgene | ASAP1 | C0041327 | Tuberculosis, Pulmonary | 1 | CTD_human |
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