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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 3523

FusionGeneSummary for ATP9A_WFDC8

check button Fusion gene summary
Fusion gene informationFusion gene name: ATP9A_WFDC8
Fusion gene ID: 3523
HgeneTgene
Gene symbol

ATP9A

WFDC8

Gene ID

10079

90199

Gene nameATPase phospholipid transporting 9A (putative)WAP four-disulfide core domain 8
SynonymsATPIIAC20orf170|HEL-S-292|WAP8|dJ461P17.1
Cytomap

20q13.2

20q13.12

Type of geneprotein-codingprotein-coding
Descriptionprobable phospholipid-transporting ATPase IIAATPase type IV, phospholipid-transporting (P-type),(putative)ATPase, class II, type 9Aphospholipid-transporting ATPase IIAWAP four-disulfide core domain protein 8WAP motif protein 1epididymis secretory protein Li 292protease inhibitor WAP8putative protease inhibitor WAP8testicular secretory protein Li 68
Modification date2018052320180519
UniProtAcc

O75110

Q8IUA0

Ensembl transtripts involved in fusion geneENST00000311637, ENST00000338821, 
ENST00000402822, ENST00000477492, 
ENST00000357199, ENST00000289953, 
Fusion gene scores* DoF score9 X 8 X 7=5041 X 1 X 1=1
# samples 91
** MAII scorelog2(9/504*10)=-2.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(1/1*10)=3.32192809488736
Context

PubMed: ATP9A [Title/Abstract] AND WFDC8 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVCOADTCGA-AD-6965-01AATP9Achr20

50286536

-WFDC8chr20

44190858

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000311637ENST00000357199ATP9Achr20

50286536

-WFDC8chr20

44190858

-
Frame-shiftENST00000311637ENST00000289953ATP9Achr20

50286536

-WFDC8chr20

44190858

-
In-frameENST00000338821ENST00000357199ATP9Achr20

50286536

-WFDC8chr20

44190858

-
Frame-shiftENST00000338821ENST00000289953ATP9Achr20

50286536

-WFDC8chr20

44190858

-
In-frameENST00000402822ENST00000357199ATP9Achr20

50286536

-WFDC8chr20

44190858

-
Frame-shiftENST00000402822ENST00000289953ATP9Achr20

50286536

-WFDC8chr20

44190858

-
intron-3CDSENST00000477492ENST00000357199ATP9Achr20

50286536

-WFDC8chr20

44190858

-
intron-3CDSENST00000477492ENST00000289953ATP9Achr20

50286536

-WFDC8chr20

44190858

-

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FusionProtFeatures for ATP9A_WFDC8


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATP9A

O75110

WFDC8

Q8IUA0


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328120_3034311048Topological domainCytoplasmic
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-13282_694311048Topological domainCytoplasmic
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328326_3324311048Topological domainExtracellular
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-132892_964311048Topological domainExtracellular
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823120_303310927Topological domainCytoplasmic
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-8232_69310927Topological domainCytoplasmic
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-82392_96310927Topological domainExtracellular
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328304_3254311048TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328333_3544311048TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-132870_914311048TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-132897_1194311048TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-82370_91310927TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-82397_119310927TransmembraneHelical
TgeneWFDC8chr20:50286536chr20:44190858ENST00000289953-06147_1948242DomainWAP 2
TgeneWFDC8chr20:50286536chr20:44190858ENST00000289953-06195_2408242DomainWAP 3
TgeneWFDC8chr20:50286536chr20:44190858ENST00000289953-0644_918242DomainWAP 1
TgeneWFDC8chr20:50286536chr20:44190858ENST00000357199-07147_1948371DomainWAP 2
TgeneWFDC8chr20:50286536chr20:44190858ENST00000357199-07195_2408371DomainWAP 3
TgeneWFDC8chr20:50286536chr20:44190858ENST00000357199-0744_918371DomainWAP 1

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-13281000_10064311048Topological domainExtracellular
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-13281031_10474311048Topological domainCytoplasmic
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328355_8414311048Topological domainCytoplasmic
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328863_8744311048Topological domainExtracellular
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328894_9234311048Topological domainCytoplasmic
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328943_9494311048Topological domainExtracellular
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328973_9784311048Topological domainCytoplasmic
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-8231000_1006310927Topological domainExtracellular
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-8231031_1047310927Topological domainCytoplasmic
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823326_332310927Topological domainExtracellular
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823355_841310927Topological domainCytoplasmic
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823863_874310927Topological domainExtracellular
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823894_923310927Topological domainCytoplasmic
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823943_949310927Topological domainExtracellular
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823973_978310927Topological domainCytoplasmic
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-13281007_10304311048TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328842_8624311048TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328875_8934311048TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328924_9424311048TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328950_9724311048TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000338821-1328979_9994311048TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-8231007_1030310927TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823304_325310927TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823333_354310927TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823842_862310927TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823875_893310927TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823924_942310927TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823950_972310927TransmembraneHelical
HgeneATP9Achr20:50286536chr20:44190858ENST00000402822-823979_999310927TransmembraneHelical


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FusionGeneSequence for ATP9A_WFDC8


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ATP9A_ENST00000311637_chr20_50286536_-_WFDC8_ENST00000357199_chr20_44190858_-_295aa
MDSRPRAGCCEWLRCCGGGEARPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTY
WVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSL
VMVALQHFAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRL

>In-frame_ATP9A_ENST00000338821_chr20_50286536_-_WFDC8_ENST00000357199_chr20_44190858_-_431aa
MTDNIPLQPVRQKKRMDSRPRAGCCEWLRCCGGGEARPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLAC
SQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSE
KNGSCFLRTDQLDGETDWKLRLPVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFTREDSDPPISESLSIENTLWAGTVVASGTVV
GVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVALQHFAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSW

>In-frame_ATP9A_ENST00000402822_chr20_50286536_-_WFDC8_ENST00000357199_chr20_44190858_-_310aa
MTDNIPLQPVRQKKRMDSRPRAGCCEWLRCCGGGEARPRTVWLGHPEKRDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLAC
SQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVN
CLTKILFGALVVVSLVMVALQHFAGRWYLQIIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRDSKIPGTVVRSSTIPEQLGRISYLLTD


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ATP9A_ENST00000311637_chr20_50286536_-_WFDC8_ENST00000357199_chr20_44190858_-_885nt
ATGGACAGCAGGCCCCGCGCCGGGTGCTGCGAGTGGCTGAGATGCTGCGGTGGAGGGGAGGCCAGGCCCCGCACTGTCTGGCTGGGGCAC
CCCGAGAAGAGAGACCAGAGGTATCCTCGGAATGTCATCAACAATCAGAAGTACAATTTCTTCACCTTTCTTCCTGGGGTGCTGTTCAAC
CAGTTCAAATACTTTTTCAACCTCTATTTCTTACTTCTTGCCTGCTCTCAGTTTGTTCCCGAAATGAGACTTGGTGCACTCTATACCTAC
TGGGTTCCCCTGGGCTTCGTGCTGGCCGTCACTGTCATCCGTGAGGCGGTGGAGGAGATCCGATGCTACGTGCGGGACAAGGAAGTCAAC
TCCCAGGTCTACAGCCGGCTCACAGCACGAGGTACTGTTGTGGGTGTTGTTCTTTACACTGGCAGAGAACTCCGGAGTGTCATGAATACC
TCAAATCCCCGAAGTAAGATCGGCCTGTTCGACTTGGAAGTGAACTGCCTCACCAAGATCCTCTTTGGTGCCCTGGTGGTGGTCTCGCTG
GTCATGGTTGCCCTTCAGCACTTTGCAGGCCGTTGGTACCTGCAGATCATCCGCTTCCTCCTCTTGTTTTCCAACATCATCCCCATTAGT
TTGCGTGTGAACCTGGACATGGGCAAGATCGTGTACAGCTGGGTGATTCGAAGGGACTCGAAAATCCCCGGGACCGTGGTTCGCTCCAGC
ACGATTCCTGAGCAGCTGGGCAGGATTTCGTACTTACTCACAGACAAGACAGGCACTCTTACCCAGAACGAGATGATTTTCAAACGGCTC

>In-frame_ATP9A_ENST00000338821_chr20_50286536_-_WFDC8_ENST00000357199_chr20_44190858_-_1293nt
ATGACGGACAACATCCCGCTGCAGCCGGTGCGCCAGAAGAAGCGGATGGACAGCAGGCCCCGCGCCGGGTGCTGCGAGTGGCTGAGATGC
TGCGGTGGAGGGGAGGCCAGGCCCCGCACTGTCTGGCTGGGGCACCCCGAGAAGAGAGACCAGAGGTATCCTCGGAATGTCATCAACAAT
CAGAAGTACAATTTCTTCACCTTTCTTCCTGGGGTGCTGTTCAACCAGTTCAAATACTTTTTCAACCTCTATTTCTTACTTCTTGCCTGC
TCTCAGTTTGTTCCCGAAATGAGACTTGGTGCACTCTATACCTACTGGGTTCCCCTGGGCTTCGTGCTGGCCGTCACTGTCATCCGTGAG
GCGGTGGAGGAGATCCGATGCTACGTGCGGGACAAGGAAGTCAACTCCCAGGTCTACAGCCGGCTCACAGCACGAGGCACAGTGAAGGTG
AAGAGTTCTAACATCCAAGTTGGAGACCTTATCATCGTTGAAAAGAACCAGCGGGTCCCTGCCGACATGATCTTCCTGAGGACATCAGAA
AAAAACGGGTCATGCTTCTTGCGGACGGATCAGCTGGATGGGGAGACGGACTGGAAGCTGCGGCTTCCCGTGGCCTGCACGCAGAGGCTC
CCCACGGCCGCCGACCTTCTTCAGATTCGATCGTATGTGTACGCAGAAGAGCCAAATATTGACATTCACAACTTCGTGGGAACTTTTACC
CGAGAAGACAGCGACCCCCCGATCAGCGAGAGCCTGAGCATAGAGAACACGCTGTGGGCTGGCACTGTGGTCGCATCAGGTACTGTTGTG
GGTGTTGTTCTTTACACTGGCAGAGAACTCCGGAGTGTCATGAATACCTCAAATCCCCGAAGTAAGATCGGCCTGTTCGACTTGGAAGTG
AACTGCCTCACCAAGATCCTCTTTGGTGCCCTGGTGGTGGTCTCGCTGGTCATGGTTGCCCTTCAGCACTTTGCAGGCCGTTGGTACCTG
CAGATCATCCGCTTCCTCCTCTTGTTTTCCAACATCATCCCCATTAGTTTGCGTGTGAACCTGGACATGGGCAAGATCGTGTACAGCTGG
GTGATTCGAAGGGACTCGAAAATCCCCGGGACCGTGGTTCGCTCCAGCACGATTCCTGAGCAGCTGGGCAGGATTTCGTACTTACTCACA
GACAAGACAGGCACTCTTACCCAGAACGAGATGATTTTCAAACGGCTCCATCTCGGAACAGTAGCCTACGGCCTCGACTCAATGGACGAA

>In-frame_ATP9A_ENST00000402822_chr20_50286536_-_WFDC8_ENST00000357199_chr20_44190858_-_930nt
ATGACGGACAACATCCCGCTGCAGCCGGTGCGCCAGAAGAAGCGGATGGACAGCAGGCCCCGCGCCGGGTGCTGCGAGTGGCTGAGATGC
TGCGGTGGAGGGGAGGCCAGGCCCCGCACTGTCTGGCTGGGGCACCCCGAGAAGAGAGACCAGAGGTATCCTCGGAATGTCATCAACAAT
CAGAAGTACAATTTCTTCACCTTTCTTCCTGGGGTGCTGTTCAACCAGTTCAAATACTTTTTCAACCTCTATTTCTTACTTCTTGCCTGC
TCTCAGTTTGTTCCCGAAATGAGACTTGGTGCACTCTATACCTACTGGGTTCCCCTGGGCTTCGTGCTGGCCGTCACTGTCATCCGTGAG
GCGGTGGAGGAGATCCGATGCTACGTGCGGGACAAGGAAGTCAACTCCCAGGTCTACAGCCGGCTCACAGCACGAGGTACTGTTGTGGGT
GTTGTTCTTTACACTGGCAGAGAACTCCGGAGTGTCATGAATACCTCAAATCCCCGAAGTAAGATCGGCCTGTTCGACTTGGAAGTGAAC
TGCCTCACCAAGATCCTCTTTGGTGCCCTGGTGGTGGTCTCGCTGGTCATGGTTGCCCTTCAGCACTTTGCAGGCCGTTGGTACCTGCAG
ATCATCCGCTTCCTCCTCTTGTTTTCCAACATCATCCCCATTAGTTTGCGTGTGAACCTGGACATGGGCAAGATCGTGTACAGCTGGGTG
ATTCGAAGGGACTCGAAAATCCCCGGGACCGTGGTTCGCTCCAGCACGATTCCTGAGCAGCTGGGCAGGATTTCGTACTTACTCACAGAC
AAGACAGGCACTCTTACCCAGAACGAGATGATTTTCAAACGGCTCCATCTCGGAACAGTAGCCTACGGCCTCGACTCAATGGACGAAGTA


* Fusion transcript sequences (Full-length transcript).
>In-frame_ATP9A_ENST00000311637_chr20_50286536_-_WFDC8_ENST00000357199_chr20_44190858_-_2052nt
GCGGATGGACAGCAGGCCCCGCGCCGGGTGCTGCGAGTGGCTGAGATGCTGCGGTGGAGGGGAGGCCAGGCCCCGCACTGTCTGGCTGGG
GCACCCCGAGAAGAGAGACCAGAGGTATCCTCGGAATGTCATCAACAATCAGAAGTACAATTTCTTCACCTTTCTTCCTGGGGTGCTGTT
CAACCAGTTCAAATACTTTTTCAACCTCTATTTCTTACTTCTTGCCTGCTCTCAGTTTGTTCCCGAAATGAGACTTGGTGCACTCTATAC
CTACTGGGTTCCCCTGGGCTTCGTGCTGGCCGTCACTGTCATCCGTGAGGCGGTGGAGGAGATCCGATGCTACGTGCGGGACAAGGAAGT
CAACTCCCAGGTCTACAGCCGGCTCACAGCACGAGGTACTGTTGTGGGTGTTGTTCTTTACACTGGCAGAGAACTCCGGAGTGTCATGAA
TACCTCAAATCCCCGAAGTAAGATCGGCCTGTTCGACTTGGAAGTGAACTGCCTCACCAAGATCCTCTTTGGTGCCCTGGTGGTGGTCTC
GCTGGTCATGGTTGCCCTTCAGCACTTTGCAGGCCGTTGGTACCTGCAGATCATCCGCTTCCTCCTCTTGTTTTCCAACATCATCCCCAT
TAGTTTGCGTGTGAACCTGGACATGGGCAAGATCGTGTACAGCTGGGTGATTCGAAGGGACTCGAAAATCCCCGGGACCGTGGTTCGCTC
CAGCACGATTCCTGAGCAGCTGGGCAGGATTTCGTACTTACTCACAGACAAGACAGGCACTCTTACCCAGAACGAGATGATTTTCAAACG
GCTCCATCTCGGAACAGTAGCCTACGGCCTCGACTCAATGGACGAAGTACAAAGCCACATTTTCAGCATTTACACCCAGGCACTTTCCTC
TCCATAGCCCCACCTTCTCCTGGAGGAATGTAGCTTTCCTGCTGCTTCTCTCCCTTGCTTTGGAGTGGACTTCTGCAATGCTGACCAAGA
AGATCAAACACAAACCAGGGTTATGTCCCAAAGAGAGGCTCACCTGTACCACTGAACTTCCGGACTCATGTAACACAGATTTTGACTGCA
AGGAATACCAGAAGTGCTGCTTTTTTGCCTGTCAGAAGAAGTGCATGGATCCCTTTCAAGAACCCTGCATGCTACCTGTGAGGCATGGAA
ACTGTAATCATGAGGCACAGCGCTGGCATTTTGACTTTAAAAATTACCGCTGCACACCCTTCAAATACAGGGGCTGCGAAGGGAATGCCA
ACAACTTCTTAAATGAGGATGCCTGCAGAACGGCCTGCATGTTAATTGTTAAGGATGGACAATGCCCACTCTTCCCTTTCACTGAACGTA
AGGAGTGTCCACCTTCATGTCACAGTGACATCGATTGTCCCCAGACAGACAAATGTTGTGAATCCAGGTGTGGCTTTGTTTGTGCCAGGG
CCTGGACAGTCAAAAAAGGTTTCTGCCCACGCAAGCCCTTGCTATGTACCAAGATTGATAAACCCAAGTGCCTGCAGGATGAGGAGTGCC
CATTGGTGGAAAAGTGCTGCTCACATTGTGGACTGAAATGTATGGACCCCAGACGTTGAATAACGGAGTTTTGCTCTTATTGCCCAGGCG
CAATCTCGGCTCACTGCAACCTCTGCTTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGCCCACC
ATCATGCCCAGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTTACCATGTTGGCCAAGCTGGTCACAAACTCCTGACCTCAGGTGAT
CCACCCACCTCAGCCTCCGAAAGTGCTGGGATCACAGGTGGGAGCCACTGTGCCTGGCCAGTTATTTCCTTTTTAAGCCTATTTCCTATC
CATTTATAGCTACTACTGAAAATGACTACTGAATTTTATCAAATACCTTTTAAGCATACAGTCACATAATGATTTTTCTCTTCTAATTTG

>In-frame_ATP9A_ENST00000338821_chr20_50286536_-_WFDC8_ENST00000357199_chr20_44190858_-_2721nt
GCGCGGCGCGGCGCGGAGCGAGCGGGCGCAGCGCGGAGCTCGGGCCCATGGTGCGCCCGTGTCCGTCGGTCGGGCCGCGCGGGCGCTCCG
CGCGTGGCCCGGCGCTCGCGAGCTCGCCCCCTCGCTGCGGGCCCGGCCCGCCCGCTGCCGCCGCCTCCTCCCCCGGGGCGGCGCGGCGCC
GGCGGGCGGCGGCGCGGAGGCCGGACCGGGCGGCGGCCCAGGCGGCGCGGGGGGCGCGGCGGCCAAGGCGGGCGGCGCCGCCGACATGAC
GGACAACATCCCGCTGCAGCCGGTGCGCCAGAAGAAGCGGATGGACAGCAGGCCCCGCGCCGGGTGCTGCGAGTGGCTGAGATGCTGCGG
TGGAGGGGAGGCCAGGCCCCGCACTGTCTGGCTGGGGCACCCCGAGAAGAGAGACCAGAGGTATCCTCGGAATGTCATCAACAATCAGAA
GTACAATTTCTTCACCTTTCTTCCTGGGGTGCTGTTCAACCAGTTCAAATACTTTTTCAACCTCTATTTCTTACTTCTTGCCTGCTCTCA
GTTTGTTCCCGAAATGAGACTTGGTGCACTCTATACCTACTGGGTTCCCCTGGGCTTCGTGCTGGCCGTCACTGTCATCCGTGAGGCGGT
GGAGGAGATCCGATGCTACGTGCGGGACAAGGAAGTCAACTCCCAGGTCTACAGCCGGCTCACAGCACGAGGCACAGTGAAGGTGAAGAG
TTCTAACATCCAAGTTGGAGACCTTATCATCGTTGAAAAGAACCAGCGGGTCCCTGCCGACATGATCTTCCTGAGGACATCAGAAAAAAA
CGGGTCATGCTTCTTGCGGACGGATCAGCTGGATGGGGAGACGGACTGGAAGCTGCGGCTTCCCGTGGCCTGCACGCAGAGGCTCCCCAC
GGCCGCCGACCTTCTTCAGATTCGATCGTATGTGTACGCAGAAGAGCCAAATATTGACATTCACAACTTCGTGGGAACTTTTACCCGAGA
AGACAGCGACCCCCCGATCAGCGAGAGCCTGAGCATAGAGAACACGCTGTGGGCTGGCACTGTGGTCGCATCAGGTACTGTTGTGGGTGT
TGTTCTTTACACTGGCAGAGAACTCCGGAGTGTCATGAATACCTCAAATCCCCGAAGTAAGATCGGCCTGTTCGACTTGGAAGTGAACTG
CCTCACCAAGATCCTCTTTGGTGCCCTGGTGGTGGTCTCGCTGGTCATGGTTGCCCTTCAGCACTTTGCAGGCCGTTGGTACCTGCAGAT
CATCCGCTTCCTCCTCTTGTTTTCCAACATCATCCCCATTAGTTTGCGTGTGAACCTGGACATGGGCAAGATCGTGTACAGCTGGGTGAT
TCGAAGGGACTCGAAAATCCCCGGGACCGTGGTTCGCTCCAGCACGATTCCTGAGCAGCTGGGCAGGATTTCGTACTTACTCACAGACAA
GACAGGCACTCTTACCCAGAACGAGATGATTTTCAAACGGCTCCATCTCGGAACAGTAGCCTACGGCCTCGACTCAATGGACGAAGTACA
AAGCCACATTTTCAGCATTTACACCCAGGCACTTTCCTCTCCATAGCCCCACCTTCTCCTGGAGGAATGTAGCTTTCCTGCTGCTTCTCT
CCCTTGCTTTGGAGTGGACTTCTGCAATGCTGACCAAGAAGATCAAACACAAACCAGGGTTATGTCCCAAAGAGAGGCTCACCTGTACCA
CTGAACTTCCGGACTCATGTAACACAGATTTTGACTGCAAGGAATACCAGAAGTGCTGCTTTTTTGCCTGTCAGAAGAAGTGCATGGATC
CCTTTCAAGAACCCTGCATGCTACCTGTGAGGCATGGAAACTGTAATCATGAGGCACAGCGCTGGCATTTTGACTTTAAAAATTACCGCT
GCACACCCTTCAAATACAGGGGCTGCGAAGGGAATGCCAACAACTTCTTAAATGAGGATGCCTGCAGAACGGCCTGCATGTTAATTGTTA
AGGATGGACAATGCCCACTCTTCCCTTTCACTGAACGTAAGGAGTGTCCACCTTCATGTCACAGTGACATCGATTGTCCCCAGACAGACA
AATGTTGTGAATCCAGGTGTGGCTTTGTTTGTGCCAGGGCCTGGACAGTCAAAAAAGGTTTCTGCCCACGCAAGCCCTTGCTATGTACCA
AGATTGATAAACCCAAGTGCCTGCAGGATGAGGAGTGCCCATTGGTGGAAAAGTGCTGCTCACATTGTGGACTGAAATGTATGGACCCCA
GACGTTGAATAACGGAGTTTTGCTCTTATTGCCCAGGCGCAATCTCGGCTCACTGCAACCTCTGCTTCCCGGGTTCAAGTGATTCTCCTG
CCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGCCCACCATCATGCCCAGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTTACCAT
GTTGGCCAAGCTGGTCACAAACTCCTGACCTCAGGTGATCCACCCACCTCAGCCTCCGAAAGTGCTGGGATCACAGGTGGGAGCCACTGT
GCCTGGCCAGTTATTTCCTTTTTAAGCCTATTTCCTATCCATTTATAGCTACTACTGAAAATGACTACTGAATTTTATCAAATACCTTTT
AAGCATACAGTCACATAATGATTTTTCTCTTCTAATTTGTTGGCATAATAAATTACTAAATTTTCTTGAGCCATCCTTGCATTCTTAATA

>In-frame_ATP9A_ENST00000402822_chr20_50286536_-_WFDC8_ENST00000357199_chr20_44190858_-_2093nt
ATGACGGACAACATCCCGCTGCAGCCGGTGCGCCAGAAGAAGCGGATGGACAGCAGGCCCCGCGCCGGGTGCTGCGAGTGGCTGAGATGC
TGCGGTGGAGGGGAGGCCAGGCCCCGCACTGTCTGGCTGGGGCACCCCGAGAAGAGAGACCAGAGGTATCCTCGGAATGTCATCAACAAT
CAGAAGTACAATTTCTTCACCTTTCTTCCTGGGGTGCTGTTCAACCAGTTCAAATACTTTTTCAACCTCTATTTCTTACTTCTTGCCTGC
TCTCAGTTTGTTCCCGAAATGAGACTTGGTGCACTCTATACCTACTGGGTTCCCCTGGGCTTCGTGCTGGCCGTCACTGTCATCCGTGAG
GCGGTGGAGGAGATCCGATGCTACGTGCGGGACAAGGAAGTCAACTCCCAGGTCTACAGCCGGCTCACAGCACGAGGTACTGTTGTGGGT
GTTGTTCTTTACACTGGCAGAGAACTCCGGAGTGTCATGAATACCTCAAATCCCCGAAGTAAGATCGGCCTGTTCGACTTGGAAGTGAAC
TGCCTCACCAAGATCCTCTTTGGTGCCCTGGTGGTGGTCTCGCTGGTCATGGTTGCCCTTCAGCACTTTGCAGGCCGTTGGTACCTGCAG
ATCATCCGCTTCCTCCTCTTGTTTTCCAACATCATCCCCATTAGTTTGCGTGTGAACCTGGACATGGGCAAGATCGTGTACAGCTGGGTG
ATTCGAAGGGACTCGAAAATCCCCGGGACCGTGGTTCGCTCCAGCACGATTCCTGAGCAGCTGGGCAGGATTTCGTACTTACTCACAGAC
AAGACAGGCACTCTTACCCAGAACGAGATGATTTTCAAACGGCTCCATCTCGGAACAGTAGCCTACGGCCTCGACTCAATGGACGAAGTA
CAAAGCCACATTTTCAGCATTTACACCCAGGCACTTTCCTCTCCATAGCCCCACCTTCTCCTGGAGGAATGTAGCTTTCCTGCTGCTTCT
CTCCCTTGCTTTGGAGTGGACTTCTGCAATGCTGACCAAGAAGATCAAACACAAACCAGGGTTATGTCCCAAAGAGAGGCTCACCTGTAC
CACTGAACTTCCGGACTCATGTAACACAGATTTTGACTGCAAGGAATACCAGAAGTGCTGCTTTTTTGCCTGTCAGAAGAAGTGCATGGA
TCCCTTTCAAGAACCCTGCATGCTACCTGTGAGGCATGGAAACTGTAATCATGAGGCACAGCGCTGGCATTTTGACTTTAAAAATTACCG
CTGCACACCCTTCAAATACAGGGGCTGCGAAGGGAATGCCAACAACTTCTTAAATGAGGATGCCTGCAGAACGGCCTGCATGTTAATTGT
TAAGGATGGACAATGCCCACTCTTCCCTTTCACTGAACGTAAGGAGTGTCCACCTTCATGTCACAGTGACATCGATTGTCCCCAGACAGA
CAAATGTTGTGAATCCAGGTGTGGCTTTGTTTGTGCCAGGGCCTGGACAGTCAAAAAAGGTTTCTGCCCACGCAAGCCCTTGCTATGTAC
CAAGATTGATAAACCCAAGTGCCTGCAGGATGAGGAGTGCCCATTGGTGGAAAAGTGCTGCTCACATTGTGGACTGAAATGTATGGACCC
CAGACGTTGAATAACGGAGTTTTGCTCTTATTGCCCAGGCGCAATCTCGGCTCACTGCAACCTCTGCTTCCCGGGTTCAAGTGATTCTCC
TGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGCCCACCATCATGCCCAGCTAATTTTTTGTATTTTTAGTAGAGATGGGGTTTTACC
ATGTTGGCCAAGCTGGTCACAAACTCCTGACCTCAGGTGATCCACCCACCTCAGCCTCCGAAAGTGCTGGGATCACAGGTGGGAGCCACT
GTGCCTGGCCAGTTATTTCCTTTTTAAGCCTATTTCCTATCCATTTATAGCTACTACTGAAAATGACTACTGAATTTTATCAAATACCTT
TTAAGCATACAGTCACATAATGATTTTTCTCTTCTAATTTGTTGGCATAATAAATTACTAAATTTTCTTGAGCCATCCTTGCATTCTTAA


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FusionGenePPI for ATP9A_WFDC8


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ATP9ACOPS6, ESR1, RIC3, SLC39A4, IFT57, LPAR1, FAM134C, ABCC3, ACADM, ATP2B4, CTR9, PLK4, NES, VPS16, ZNF644, RANBP6, B4GAT1, SPPL2B, TMED2, IPPK, COMMD8, SCN3B, YIPF3, SYP, C3AR1, SLC1A5, SLC22A9, FPR2, ATP2B2, SLC15A1WFDC8UBC


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ATP9A_WFDC8


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ATP9A_WFDC8


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource