	FusionGeneSummary
	FusionProtFeature
	FusionGeneSequence
	FusionGenePPI
	RelatedDrugs
	RelatedDiseases

Fusion gene ID: 35104

FusionGeneSummary for SNHG14_STARD3

Fusion gene summary

Fusion gene information	Fusion gene name: SNHG14_STARD3
	Fusion gene ID: 35104
		Hgene	Tgene
	Gene symbol	SNHG14	STARD3
	Gene ID	104472715	10948
	Gene name	small nucleolar RNA host gene 14	StAR related lipid transfer domain containing 3
	Synonyms	115HG\|IC-SNURF-SNRPN\|LNCAT\|NCRNA00214\|U-UBE3A-ATS\|UBE3A-AS\|UBE3A-AS1\|UBE3AATS	CAB1\|MLN64\|es64
	Cytomap	15q11.2	17q12
	Type of gene	ncRNA	protein-coding
	Description	UBE3A antisense RNA 1 (non-protein coding)UBE3A antisense transcriptlarge noncoding antisense transcriptsmall nucleolar RNA host gene 14 (non-protein coding)	stAR-related lipid transfer protein 3MLN 64START domain-containing protein 3StAR-related lipid transfer (START) domain containing 3metastatic lymph node gene 64 proteinmetastatic lymph node protein 64steroidogenic acute regulatory protein related
	Modification date	20180329	20180522
	UniProtAcc		Q14849
	Ensembl transtripts involved in fusion gene	ENST00000549804, ENST00000547292, ENST00000424208, ENST00000452731, ENST00000554726, ENST00000551631, ENST00000459433, ENST00000551361, ENST00000553134, ENST00000551938, ENST00000384733, ENST00000551077, ENST00000546682, ENST00000553108, ENST00000384430, ENST00000516123, ENST00000553149, ENST00000441592, ENST00000365306, ENST00000414175, ENST00000456576, ENST00000363358, ENST00000424333, ENST00000450809, ENST00000453082, ENST00000365067, ENST00000390982, ENST00000580438,	ENST00000336308, ENST00000578232, ENST00000544210, ENST00000394250, ENST00000580611,
Fusion gene scores	* DoF score	2 X 2 X 2=8	10 X 3 X 7=210
	# samples	2	10
	** MAII score	log2(2/8*10)=1.32192809488736	log2(10/210*10)=-1.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: SNHG14 [Title/Abstract] AND STARD3 [Title/Abstract] AND fusion [Title/Abstract]
Functional or gene categories assigned by FusionGDB annotation

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	STARD3	GO:0030301	cholesterol transport	28377464
Tgene	STARD3	GO:0099044	vesicle tethering to endoplasmic reticulum	24105263\|28377464

Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Data type	Source	Cancer type	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
TCGA	LD	BRCA	TCGA-UL-AAZ6-01A	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+

* LD: Li Ding group's fusion gene list
RV: Roel Verhaak group's fusion gene list
ChiTaRs fusion database

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
intron-3CDS	ENST00000549804	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000549804	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000549804	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000549804	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000549804	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000547292	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000547292	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000547292	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000547292	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000547292	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000424208	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000424208	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000424208	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000424208	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000424208	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
3UTR-3CDS	ENST00000452731	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
3UTR-intron	ENST00000452731	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
3UTR-intron	ENST00000452731	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
3UTR-intron	ENST00000452731	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
3UTR-intron	ENST00000452731	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000554726	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000554726	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000554726	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000554726	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000554726	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000551631	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551631	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551631	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551631	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551631	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000459433	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000459433	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000459433	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000459433	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000459433	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000551361	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551361	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551361	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551361	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551361	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000553134	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000553134	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000553134	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000553134	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000553134	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000551938	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551938	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551938	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551938	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551938	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000384733	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000384733	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000384733	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000384733	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000384733	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000551077	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551077	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551077	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551077	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000551077	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000546682	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000546682	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000546682	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000546682	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000546682	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000553108	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000553108	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000553108	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000553108	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000553108	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000384430	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000384430	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000384430	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000384430	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000384430	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000516123	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000516123	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000516123	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000516123	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000516123	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000553149	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000553149	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000553149	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000553149	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000553149	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000441592	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000441592	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000441592	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000441592	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000441592	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000365306	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000365306	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000365306	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000365306	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000365306	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000414175	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000414175	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000414175	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000414175	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000414175	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000456576	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000456576	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000456576	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000456576	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000456576	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000363358	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000363358	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000363358	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000363358	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000363358	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000424333	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000424333	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000424333	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000424333	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000424333	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000450809	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000450809	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000450809	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000450809	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000450809	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000453082	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000453082	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000453082	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000453082	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000453082	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000365067	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000365067	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000365067	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000365067	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000365067	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000390982	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000390982	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000390982	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000390982	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000390982	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-3CDS	ENST00000580438	ENST00000336308	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000580438	ENST00000578232	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000580438	ENST00000544210	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000580438	ENST00000394250	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+
intron-intron	ENST00000580438	ENST00000580611	SNHG14	chr15	25497480	+	STARD3	chr17	37816464	+

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FusionProtFeatures for SNHG14_STARD3

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
SNHG14	STARD3 Q14849
Lectin that binds to various sugars: galactose > mannose= fucose > N-acetylglucosamine > N-acetylgalactosamine(PubMed:10224141). Acts as a chemoattractant, probably involved inthe regulation of cell migration (PubMed:28301481).{ECO:0000269\|PubMed:10224141, ECO:0000269\|PubMed:28301481}.	Sterol-binding protein that mediates cholesteroltransport from the endoplasmic reticulum to endosomes(PubMed:11053434, PubMed:15930133, PubMed:22514632,PubMed:28377464). Creates contact site between the endoplasmicreticulum and late endosomes: localizes to late endosome membranesand contacts the endoplasmic reticulum via interaction with VAPAand VAPB (PubMed:24105263, PubMed:28377464). Acts as a lipidtransfer protein that redirects sterol to the endosome at theexpense of the cell membrane and favors membrane formation insideendosomes (PubMed:28377464). May also mediate cholesteroltransport between other membranes, such as mitochondria membraneor cell membrane (PubMed:12070139, PubMed:19965586). However, suchresults need additional experimental evidences; probably mainlymediates cholesterol transport from the endoplasmic reticulum toendosomes (PubMed:28377464). Does not activate transcriptionalcholesterol sensing (PubMed:28377464). Able to bind other lipids,such as lutein, a xanthophyll carotenoids that form the macularpigment of the retina (PubMed:21322544).{ECO:0000269\|PubMed:11053434, ECO:0000269\|PubMed:12070139,ECO:0000269\|PubMed:15930133, ECO:0000269\|PubMed:19965586,ECO:0000269\|PubMed:21322544, ECO:0000269\|PubMed:22514632,ECO:0000269\|PubMed:24105263, ECO:0000269\|PubMed:28377464}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page
.

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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FusionGeneSequence for SNHG14_STARD3

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

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FusionGenePPI for SNHG14_STARD3

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page
.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene	Hgene's interactors	Tgene	Tgene's interactors
SNHG14		STARD3	GOPC, SPACA1, SDF4, ERGIC3, HEPACAM2, VAPB, CREB3, C19orf26, MME, P2RX2, SLC15A1, CHRM3, MANSC1, PMEL, CLEC2D, TSPYL6, TRIM25, LMNA

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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RelatedDrugs for SNHG14_STARD3

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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RelatedDiseases for SNHG14_STARD3

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner	Gene	Disease ID	Disease name	# pubmeds	Source
Tgene	STARD3	C0033578	Prostatic Neoplasms	2	CTD_human
Tgene	STARD3	C3496069	cocaine use	1	PSYGENET

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Fusion gene ID: 35104

FusionGeneSummary for SNHG14_STARD3

FusionProtFeatures for SNHG14_STARD3

FusionGeneSequence for SNHG14_STARD3

FusionGenePPI for SNHG14_STARD3

RelatedDrugs for SNHG14_STARD3

RelatedDiseases for SNHG14_STARD3