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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 34657

FusionGeneSummary for SLCO2A1_SLC25A36

check button Fusion gene summary
Fusion gene informationFusion gene name: SLCO2A1_SLC25A36
Fusion gene ID: 34657
HgeneTgene
Gene symbol

SLCO2A1

SLC25A36

Gene ID

6578

55186

Gene namesolute carrier organic anion transporter family member 2A1solute carrier family 25 member 36
SynonymsMATR1|OATP2A1|PGT|PHOAR2|SLC21A2PNC2
Cytomap

3q22.1-q22.2

3q23

Type of geneprotein-codingprotein-coding
Descriptionsolute carrier organic anion transporter family member 2A1matrin F/G 1solute carrier family 21 (prostaglandin transporter), member 2solute carrier family 25 member 36solute carrier family 25 (pyrimidine nucleotide carrier ), member 36
Modification date2018052320180523
UniProtAcc

Q92959

Q96CQ1

Ensembl transtripts involved in fusion geneENST00000310926, ENST00000493729, 
ENST00000478651, 		ENST00000446041, 
ENST00000393015, ENST00000507429, 
ENST00000324194, ENST00000453248, 
Fusion gene scores* DoF score4 X 4 X 2=323 X 4 X 2=24
# samples 44
** MAII scorelog2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(4/24*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: SLCO2A1 [Title/Abstract] AND SLC25A36 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSLC25A36

GO:0000002

mitochondrial genome maintenance

25320081

TgeneSLC25A36

GO:0006864

pyrimidine nucleotide transport

25320081

TgeneSLC25A36

GO:0007005

mitochondrion organization

25320081

TgeneSLC25A36

GO:0051881

regulation of mitochondrial membrane potential

25320081


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDLUSCTCGA-77-7338-01ASLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000310926ENST00000446041SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
5CDS-intronENST00000310926ENST00000393015SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
5CDS-intronENST00000310926ENST00000507429SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
5CDS-intronENST00000310926ENST00000324194SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
5CDS-intronENST00000310926ENST00000453248SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
In-frameENST00000493729ENST00000446041SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
5CDS-intronENST00000493729ENST00000393015SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
5CDS-intronENST00000493729ENST00000507429SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
5CDS-intronENST00000493729ENST00000324194SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
5CDS-intronENST00000493729ENST00000453248SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
5UTR-3CDSENST00000478651ENST00000446041SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
5UTR-intronENST00000478651ENST00000393015SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
5UTR-intronENST00000478651ENST00000507429SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
5UTR-intronENST00000478651ENST00000324194SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+
5UTR-intronENST00000478651ENST00000453248SLCO2A1chr3

133692507

-SLC25A36chr3

140689769

+

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FusionProtFeatures for SLCO2A1_SLC25A36


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SLCO2A1

Q92959

SLC25A36

Q96CQ1

May mediate the release of newly synthesizedprostaglandins from cells, the transepithelial transport ofprostaglandins, and the clearance of prostaglandins from thecirculation. Transports PGD2, as well as PGE1, PGE2 and PGF2A. Mitochondrial transporter that imports/exportspyrimidine nucleotides into and from mitochondria. Transportspreferentially cytosine and uracil (deoxy)nucleoside mono-, di-,and triphosphates by uniport and antiport mechanism. Alsotransports guanine but not adenine (deoxy)nucleotides. Isinhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury dichloride,Mersalyl acid, p-hydroxymercuribenzoate). Participates inmitochondrial genome maintenance, regulation of mitochondrialmembrane potential and mitochondrial respiration.{ECO:0000269|PubMed:25320081}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-3141_32132644Topological domainCytoplasmic
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-31453_71132644Topological domainExtracellular
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-31493_98132644Topological domainCytoplasmic
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-31433_52132644TransmembraneHelical%3B Name%3D1
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-31472_92132644TransmembraneHelical%3B Name%3D2
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-31499_123132644TransmembraneHelical%3B Name%3D3
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000324194+37224_308128312RepeatSolcar 3
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000446041+37224_308128311RepeatSolcar 3
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000324194+37180_200128312TransmembraneHelical%3B Name%3D4
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000324194+37226_246128312TransmembraneHelical%3B Name%3D5
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000324194+37291_311128312TransmembraneHelical%3B Name%3D6
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000446041+37180_200128311TransmembraneHelical%3B Name%3D4
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000446041+37226_246128311TransmembraneHelical%3B Name%3D5
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000446041+37291_311128311TransmembraneHelical%3B Name%3D6

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314438_496132644DomainKazal-like
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314124_167132644Topological domainExtracellular
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314197_215132644Topological domainCytoplasmic
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314237_254132644Topological domainExtracellular
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314280_321132644Topological domainCytoplasmic
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314344_363132644Topological domainExtracellular
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314388_391132644Topological domainCytoplasmic
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314416_518132644Topological domainExtracellular
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314542_550132644Topological domainCytoplasmic
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314577_610132644Topological domainExtracellular
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314630_643132644Topological domainCytoplasmic
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314168_196132644TransmembraneHelical%3B Name%3D4
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314216_236132644TransmembraneHelical%3B Name%3D5
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314255_279132644TransmembraneHelical%3B Name%3D6
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314322_343132644TransmembraneHelical%3B Name%3D7
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314364_387132644TransmembraneHelical%3B Name%3D8
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314392_415132644TransmembraneHelical%3B Name%3D9
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314519_541132644TransmembraneHelical%3B Name%3D10
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314551_576132644TransmembraneHelical%3B Name%3D11
HgeneSLCO2A1chr3:133692507chr3:140689769ENST00000310926-314611_629132644TransmembraneHelical%3B Name%3D12
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000324194+37116_203128312RepeatSolcar 2
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000324194+374_108128312RepeatSolcar 1
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000446041+37116_203128311RepeatSolcar 2
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000446041+374_108128311RepeatSolcar 1
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000324194+37111_131128312TransmembraneHelical%3B Name%3D3
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000324194+3741_57128312TransmembraneHelical%3B Name%3D2
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000324194+377_27128312TransmembraneHelical%3B Name%3D1
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000446041+37111_131128311TransmembraneHelical%3B Name%3D3
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000446041+3741_57128311TransmembraneHelical%3B Name%3D2
TgeneSLC25A36chr3:133692507chr3:140689769ENST00000446041+377_27128311TransmembraneHelical%3B Name%3D1


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FusionGeneSequence for SLCO2A1_SLC25A36


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_SLCO2A1_ENST00000310926_chr3_133692507_-_SLC25A36_ENST00000446041_chr3_140689769_+_315aa
MGLLPKLGASQGSDTSTSRAGRCARSVFGNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFVSY
FGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGF
YRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHVVRTRLREEGTKYRSFFQT

>In-frame_SLCO2A1_ENST00000493729_chr3_133692507_-_SLC25A36_ENST00000446041_chr3_140689769_+_315aa
MGLLPKLGASQGSDTSTSRAGRCARSVFGNIKVFVLCQGLLQLCQLLYSAYFKSSLTTIEKRFGLSSSSSGLISSLNEISNAILIIFVSY
FGSRVHRPRLIGIGGLFLAAGAFILTLPHFLSEPYQYTLASTGFTAITATNPIWLIKTRLQLDARNRGERRMGAFECVRKVYQTDGLKGF
YRGMSASYAGISETVIHFVIYESIKQKLLEYKTASTMENDEESVKEASDFVGMMLAAATSKTCATTIAYPHVVRTRLREEGTKYRSFFQT


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_SLCO2A1_ENST00000310926_chr3_133692507_-_SLC25A36_ENST00000446041_chr3_140689769_+_945nt
ATGGGGCTCCTGCCCAAGCTCGGCGCGTCCCAGGGCAGCGACACCTCTACTAGCCGAGCCGGCCGCTGTGCCCGCTCGGTCTTCGGCAAC
ATTAAGGTGTTTGTGCTCTGCCAAGGCCTCCTGCAGCTCTGCCAACTCCTGTACAGCGCCTACTTCAAGAGCAGCCTCACCACCATTGAG
AAGCGCTTTGGGCTCTCCAGTTCTTCATCGGGTCTCATTTCCAGCTTGAATGAGATCAGCAATGCCATCCTCATCATCTTTGTCAGCTAC
TTTGGCAGCCGGGTGCACCGTCCACGTCTGATTGGCATCGGAGGTCTCTTCCTGGCTGCAGGTGCCTTCATCCTCACCCTCCCACACTTC
CTCTCCGAGCCCTACCAGTACACCTTGGCCAGCACTGGTTTTACTGCAATCACAGCAACCAACCCCATTTGGCTTATAAAGACTCGGTTA
CAGCTTGATGCAAGGAACCGCGGGGAAAGGCGAATGGGTGCTTTTGAATGTGTTCGTAAAGTGTATCAGACAGATGGACTAAAAGGATTT
TATAGGGGCATGTCTGCTTCATATGCTGGTATATCAGAGACTGTTATCCATTTTGTTATTTATGAAAGTATAAAACAAAAACTACTGGAA
TATAAGACTGCTTCTACAATGGAAAATGATGAAGAGTCTGTGAAAGAAGCATCAGATTTTGTGGGAATGATGCTAGCTGCTGCCACCTCA
AAAACTTGTGCCACAACTATAGCATATCCACATGTTGTAAGAACAAGACTACGTGAAGAGGGAACAAAATACAGATCTTTTTTTCAGACT
CTATCTTTGCTTGTTCAAGAAGAAGGTTATGGGTCTCTTTATCGTGGTCTGACAACTCATCTAGTGAGACAGATTCCAAACACAGCCATT

>In-frame_SLCO2A1_ENST00000493729_chr3_133692507_-_SLC25A36_ENST00000446041_chr3_140689769_+_945nt
ATGGGGCTCCTGCCCAAGCTCGGCGCGTCCCAGGGCAGCGACACCTCTACTAGCCGAGCCGGCCGCTGTGCCCGCTCGGTCTTCGGCAAC
ATTAAGGTGTTTGTGCTCTGCCAAGGCCTCCTGCAGCTCTGCCAACTCCTGTACAGCGCCTACTTCAAGAGCAGCCTCACCACCATTGAG
AAGCGCTTTGGGCTCTCCAGTTCTTCATCGGGTCTCATTTCCAGCTTGAATGAGATCAGCAATGCCATCCTCATCATCTTTGTCAGCTAC
TTTGGCAGCCGGGTGCACCGTCCACGTCTGATTGGCATCGGAGGTCTCTTCCTGGCTGCAGGTGCCTTCATCCTCACCCTCCCACACTTC
CTCTCCGAGCCCTACCAGTACACCTTGGCCAGCACTGGTTTTACTGCAATCACAGCAACCAACCCCATTTGGCTTATAAAGACTCGGTTA
CAGCTTGATGCAAGGAACCGCGGGGAAAGGCGAATGGGTGCTTTTGAATGTGTTCGTAAAGTGTATCAGACAGATGGACTAAAAGGATTT
TATAGGGGCATGTCTGCTTCATATGCTGGTATATCAGAGACTGTTATCCATTTTGTTATTTATGAAAGTATAAAACAAAAACTACTGGAA
TATAAGACTGCTTCTACAATGGAAAATGATGAAGAGTCTGTGAAAGAAGCATCAGATTTTGTGGGAATGATGCTAGCTGCTGCCACCTCA
AAAACTTGTGCCACAACTATAGCATATCCACATGTTGTAAGAACAAGACTACGTGAAGAGGGAACAAAATACAGATCTTTTTTTCAGACT
CTATCTTTGCTTGTTCAAGAAGAAGGTTATGGGTCTCTTTATCGTGGTCTGACAACTCATCTAGTGAGACAGATTCCAAACACAGCCATT


* Fusion transcript sequences (Full-length transcript).
>In-frame_SLCO2A1_ENST00000310926_chr3_133692507_-_SLC25A36_ENST00000446041_chr3_140689769_+_4699nt
ACACCTGTCTGAGGGGGCGGCGGCGGCGGCGGCGGCGGGGCGGGGGCTCGTAGCGCCTTTGACACCCGAGGAAAAGAGGGAGGAGGGAGA
GCGCGTTTCATCATCGGCGGCGGCCACTTATAAAAACTTCTAGGCGCGCACTCGCTGGCTCAGTCTCCGCTCCGCGAATCTCCTCCGGCC
ACTGCCGCCGCGGTCGCCTCTCACCCGCCCGGCCGCTCCAGCCCGAGGCGCCCCGACCCCGCGCCACTCCGCGCCCGGCCAGCCGCCCGC
AGCCATGGGGCTCCTGCCCAAGCTCGGCGCGTCCCAGGGCAGCGACACCTCTACTAGCCGAGCCGGCCGCTGTGCCCGCTCGGTCTTCGG
CAACATTAAGGTGTTTGTGCTCTGCCAAGGCCTCCTGCAGCTCTGCCAACTCCTGTACAGCGCCTACTTCAAGAGCAGCCTCACCACCAT
TGAGAAGCGCTTTGGGCTCTCCAGTTCTTCATCGGGTCTCATTTCCAGCTTGAATGAGATCAGCAATGCCATCCTCATCATCTTTGTCAG
CTACTTTGGCAGCCGGGTGCACCGTCCACGTCTGATTGGCATCGGAGGTCTCTTCCTGGCTGCAGGTGCCTTCATCCTCACCCTCCCACA
CTTCCTCTCCGAGCCCTACCAGTACACCTTGGCCAGCACTGGTTTTACTGCAATCACAGCAACCAACCCCATTTGGCTTATAAAGACTCG
GTTACAGCTTGATGCAAGGAACCGCGGGGAAAGGCGAATGGGTGCTTTTGAATGTGTTCGTAAAGTGTATCAGACAGATGGACTAAAAGG
ATTTTATAGGGGCATGTCTGCTTCATATGCTGGTATATCAGAGACTGTTATCCATTTTGTTATTTATGAAAGTATAAAACAAAAACTACT
GGAATATAAGACTGCTTCTACAATGGAAAATGATGAAGAGTCTGTGAAAGAAGCATCAGATTTTGTGGGAATGATGCTAGCTGCTGCCAC
CTCAAAAACTTGTGCCACAACTATAGCATATCCACATGTTGTAAGAACAAGACTACGTGAAGAGGGAACAAAATACAGATCTTTTTTTCA
GACTCTATCTTTGCTTGTTCAAGAAGAAGGTTATGGGTCTCTTTATCGTGGTCTGACAACTCATCTAGTGAGACAGATTCCAAACACAGC
CATTATGATGGCCACCTATGAATTGGTGGTTTACCTACTCAATGGATAGCAGCACGAGGACTGCTGTACTGCAAAAAAAGAAGACCAAAA
GATTACAGTGGACCATGGGATACAGAAGCCAGCATGGCAGACAGAAGAAAAATAGTTTGGGAACATGTAACTATTCTAAGTGGAAGTTTT
GTTGTAGGAATTATAGTAATCACACCACATTACTTGGCCTTTCGGTAATGTGAAAAAAAAAAAAAACCTCAGAGCCTCCAAGGAAATGCC
TTTAGAAGCACTCCTCTCTCAAAATTGCCATTTTCTCTACCATGTCCCCCAGACACAGTTGGGTTTTGTTGATTTATGGCAGTCTTCTAA
ACAAAGCCATCCTTAATTTTACATACTGTATTGTAACTATCCAAAGATAGTATTGGCAGTCATAAATTTATAACTTCTGGCCTTTGTTTA
ATTCCAGTAAAATAACAGCAATGACAATGAGATCGTCAGTATTATTTTCACATTTCCCTGAGAGGACCTGGCACAATATTTTAAATTTAA
TTATTTGGCAGTAGTCACTGTTTTTGACAACCAATGAAATAGCGTCTAAATATCTTGTATATTTTTTAGCATCAAAATGTTTTGGTTTCC
ACTGCTGACAGGTGCTTGTTGTTTAGCCTAATGTGGATATTTAAATTGTTAACATACCAAACACACATGGTAATAGTTTGGGACAAAATA
ACTAGTAAAATGTTGATTTCTCGGCTTTTTCACTGACTGCGGCATGTCCTCGTGTCTTCTCTGATTTTGTGGTACATGAATGAATGCATT
TATCTTTTTAGTGACTTACTAGTTACGAACTTGAATTATCACCTCTTTGTCATACTTAAGTATCATTTACATAAAGTGTAAAAGATTTTT
TCACTTTTGAATCTTTACCTACTTGCTTTCACATTAAGAATTTGAACTTTTGAGTTTTTTCCAGGTCTATATATAATAGATTACATTTAT
TTTGTAAAGAAAATAGTAATTTAAAGTTTTGCCATTTTAAGGTGACAATATTTGGGACAGTATAAATATTATAGACAAGGGCCCCCTTGC
TGTCTGCTTTAGCAGGTAGTGACATTAATTGACTTATAGTTTTGTGTAAATGAACAAACTGCTTTTGACAAGAAATTTATTCTGTCCTAG
TTTCCTGCGTGGTAAATCATAGAAAGATTCAAGTTCATTTGGGTTAAATGTGCTAATAGGATGTAGCTTTTAAATTCTGCTATTGAGTCA
GCTGTACCTTTTAATACTTTAAATGTGTTATTTGTATGGCCCTTATAAAGGTGTTTGCTGTAATTCTGTTAAAAGACTTCGCCTATGCCA
TACTGGTGTATAAAAACTGCCGCAATTGGACGCCGGTGTGGTACTCATTTCAGTATACCTGAACTGTACATTTTGTGCAATGGCTTTATC
TAAAAGAATGACGCTTCGTGAAAGCACTTTGTGGCCTTTTTTGGGGGGGAGGGTGAGAGAGTAGGAGAGAATACCATGTTAAGATTAAAA
AAAAAAACAAAAACATTGGTCACGTATTAGGCAGAAACAGTGTTCATAACATTTTTCTGGGTTTTAAATATGTTGTTTCGGATATCCTTA
ATATAAATGTTTTAGGTATTCTGTGTACCCTGTCGTACCCCCAACATTATAGAATATTGCAGCGTGTCATTGCAAGCTTTCTCTGCTGTC
ACCAGTGAAACATAGTGCCCTGTTAAATTCCCCCACTTTAACTTCCTTGTGATCAACAGTAACTGGATGTTTTTGAGGTGCTCAATTGGA
ATAAAAATATTCCAATCTATTTGGAGACCAAAGGCAAAATCAGTTTTCTTACCTTTGGAATTATTCGTACCTTTTATGGTAAATTTCAGC
TTTGACATGTATTATGAGGAACGTACCAAAAACCGGTTTGTAACAAATCTGTAGAGAAGGTCTGAATCTATCGTGTTTGCCTTTTCAGGT
GCCATTTCTACTGCCTAATACAGTGCCATTTGCCTTGTGAAGACCCATAAACATTCATTGTGTTGAATGTAAGATAGAGACTCTCCCTAG
TCTTACTGATCTCAGTACCCCACAAATGATTAAGAATGATATGAAAACCAGCAGCTAAGGAACATCTTATTATTTAGTTGTAGCATATTC
ATAACAAGTGTCCTTCAAGGATAAACATATATTCTCTATTTGTATTTAGCAAGTAAAACTTGTGTTGACCTTTAGTGCATTATATTCAGC
TTTTAACAGTATTATGTATGTACTGGAAAGCAAAGAAATCTTAGAGTCTTGGACATTGTTTATTTGTGCAACAACTAGAAAGGAGCAATG
AAGTTTATTTCAGTTGTATTTTTCCCTAAGCACAATCTGCAATAGTTTATGTATGACAGAGATAATTCAAAAAGGAAAACTATATATAAA
AGTTGTATATAAAGTTTGTCTCTGAAATATTTCTTTGAAGTTTTTAAAAAATCGACTCATGTTTAAAAACAAAAACACATATTCAGAGCA
TTGGACTTTTTTAACTTGTTTTCATCTGTTTATCATGACTTTTTTATTTCTGGTGTAGAGTCCACATTATTTAGTTTGTTGTACTTTTAA
ATTTCAAAGTTCAAATCTGAAGAATTAGCGTTTGTGATTTCGGGATACCATGCAGTGGTTTTAATCCCAGGAAAAAAACTATCACCAAAA
GTTCGTTTGATTCTCATTATGTAACTTTGTAGAACCATCCTTTCTAGATGGGTCCACCACAGTGAATTTGTAACTTTGAAGTCAGGATAG
AATATCATTAGATTATCTGTGAGATAGCATTACTATGTTAGGACCAGCAGAGTTTGGGTTGGTAAAAATAATGTTTGCTCTATTACTGGG
TTACAGACATTTCAGCATTTTTAGGTTGGTTTTAAATCACTAAAAATATTTATTCGGATTTGAAGGATTTAAGTGCTAAAAATCAATCCA
TTTCTTGCCCTTCAATAATTGTCCATGCCTGCCTTTTGTTGTTTACATGCTCTTCTGCCCAGACTGTTAGTAATCTAGGGACCCCCTTTG
GAGCTGATAAGTACAGTTCAGCCTTTTCTCCTCAAATATATAATGACTTTAACATTCCTAAGAATATAGGTATTTCTGAATGATTTAAAT
TTGAGGAATTTTAATACATAAAATACAATGTACAAACTTTCTGCCCACTCAGATCTCTTCTCCATCATGTACTTAGTATTTCCCATTAAC
CTACACACTGATTTTTATGCTACTCCTTGTAGAAACAAAATTCTGGTTTGACTCAGTTTTTGTGTTTATAAACTTTTGGAATGTGTACCC
CGTTTATGTGAAGAATTATGACCTATCAGTCATAGCTAAATAGTGAACCTCAAAAGTGTTAACTTTTGACTATTCATGTGAGGTTTGGTA
TCTTGCATTTATGTACATGGCTGTAAATTATGTGCATTTACTCTGTATTTATGTTATCTAGCTGACTTTTACTTGAATTGTTCAAATTTT

>In-frame_SLCO2A1_ENST00000493729_chr3_133692507_-_SLC25A36_ENST00000446041_chr3_140689769_+_4537nt
CGCGAATCTCCTCCGGCCACTGCCGCCGCGGTCGCCTCTCACCCGCCCGGCCGCTCCAGCCCGAGGCGCCCCGACCCCGCGCCACTCCGC
GCCCGGCCAGCCGCCCGCAGCCATGGGGCTCCTGCCCAAGCTCGGCGCGTCCCAGGGCAGCGACACCTCTACTAGCCGAGCCGGCCGCTG
TGCCCGCTCGGTCTTCGGCAACATTAAGGTGTTTGTGCTCTGCCAAGGCCTCCTGCAGCTCTGCCAACTCCTGTACAGCGCCTACTTCAA
GAGCAGCCTCACCACCATTGAGAAGCGCTTTGGGCTCTCCAGTTCTTCATCGGGTCTCATTTCCAGCTTGAATGAGATCAGCAATGCCAT
CCTCATCATCTTTGTCAGCTACTTTGGCAGCCGGGTGCACCGTCCACGTCTGATTGGCATCGGAGGTCTCTTCCTGGCTGCAGGTGCCTT
CATCCTCACCCTCCCACACTTCCTCTCCGAGCCCTACCAGTACACCTTGGCCAGCACTGGTTTTACTGCAATCACAGCAACCAACCCCAT
TTGGCTTATAAAGACTCGGTTACAGCTTGATGCAAGGAACCGCGGGGAAAGGCGAATGGGTGCTTTTGAATGTGTTCGTAAAGTGTATCA
GACAGATGGACTAAAAGGATTTTATAGGGGCATGTCTGCTTCATATGCTGGTATATCAGAGACTGTTATCCATTTTGTTATTTATGAAAG
TATAAAACAAAAACTACTGGAATATAAGACTGCTTCTACAATGGAAAATGATGAAGAGTCTGTGAAAGAAGCATCAGATTTTGTGGGAAT
GATGCTAGCTGCTGCCACCTCAAAAACTTGTGCCACAACTATAGCATATCCACATGTTGTAAGAACAAGACTACGTGAAGAGGGAACAAA
ATACAGATCTTTTTTTCAGACTCTATCTTTGCTTGTTCAAGAAGAAGGTTATGGGTCTCTTTATCGTGGTCTGACAACTCATCTAGTGAG
ACAGATTCCAAACACAGCCATTATGATGGCCACCTATGAATTGGTGGTTTACCTACTCAATGGATAGCAGCACGAGGACTGCTGTACTGC
AAAAAAAGAAGACCAAAAGATTACAGTGGACCATGGGATACAGAAGCCAGCATGGCAGACAGAAGAAAAATAGTTTGGGAACATGTAACT
ATTCTAAGTGGAAGTTTTGTTGTAGGAATTATAGTAATCACACCACATTACTTGGCCTTTCGGTAATGTGAAAAAAAAAAAAAACCTCAG
AGCCTCCAAGGAAATGCCTTTAGAAGCACTCCTCTCTCAAAATTGCCATTTTCTCTACCATGTCCCCCAGACACAGTTGGGTTTTGTTGA
TTTATGGCAGTCTTCTAAACAAAGCCATCCTTAATTTTACATACTGTATTGTAACTATCCAAAGATAGTATTGGCAGTCATAAATTTATA
ACTTCTGGCCTTTGTTTAATTCCAGTAAAATAACAGCAATGACAATGAGATCGTCAGTATTATTTTCACATTTCCCTGAGAGGACCTGGC
ACAATATTTTAAATTTAATTATTTGGCAGTAGTCACTGTTTTTGACAACCAATGAAATAGCGTCTAAATATCTTGTATATTTTTTAGCAT
CAAAATGTTTTGGTTTCCACTGCTGACAGGTGCTTGTTGTTTAGCCTAATGTGGATATTTAAATTGTTAACATACCAAACACACATGGTA
ATAGTTTGGGACAAAATAACTAGTAAAATGTTGATTTCTCGGCTTTTTCACTGACTGCGGCATGTCCTCGTGTCTTCTCTGATTTTGTGG
TACATGAATGAATGCATTTATCTTTTTAGTGACTTACTAGTTACGAACTTGAATTATCACCTCTTTGTCATACTTAAGTATCATTTACAT
AAAGTGTAAAAGATTTTTTCACTTTTGAATCTTTACCTACTTGCTTTCACATTAAGAATTTGAACTTTTGAGTTTTTTCCAGGTCTATAT
ATAATAGATTACATTTATTTTGTAAAGAAAATAGTAATTTAAAGTTTTGCCATTTTAAGGTGACAATATTTGGGACAGTATAAATATTAT
AGACAAGGGCCCCCTTGCTGTCTGCTTTAGCAGGTAGTGACATTAATTGACTTATAGTTTTGTGTAAATGAACAAACTGCTTTTGACAAG
AAATTTATTCTGTCCTAGTTTCCTGCGTGGTAAATCATAGAAAGATTCAAGTTCATTTGGGTTAAATGTGCTAATAGGATGTAGCTTTTA
AATTCTGCTATTGAGTCAGCTGTACCTTTTAATACTTTAAATGTGTTATTTGTATGGCCCTTATAAAGGTGTTTGCTGTAATTCTGTTAA
AAGACTTCGCCTATGCCATACTGGTGTATAAAAACTGCCGCAATTGGACGCCGGTGTGGTACTCATTTCAGTATACCTGAACTGTACATT
TTGTGCAATGGCTTTATCTAAAAGAATGACGCTTCGTGAAAGCACTTTGTGGCCTTTTTTGGGGGGGAGGGTGAGAGAGTAGGAGAGAAT
ACCATGTTAAGATTAAAAAAAAAAACAAAAACATTGGTCACGTATTAGGCAGAAACAGTGTTCATAACATTTTTCTGGGTTTTAAATATG
TTGTTTCGGATATCCTTAATATAAATGTTTTAGGTATTCTGTGTACCCTGTCGTACCCCCAACATTATAGAATATTGCAGCGTGTCATTG
CAAGCTTTCTCTGCTGTCACCAGTGAAACATAGTGCCCTGTTAAATTCCCCCACTTTAACTTCCTTGTGATCAACAGTAACTGGATGTTT
TTGAGGTGCTCAATTGGAATAAAAATATTCCAATCTATTTGGAGACCAAAGGCAAAATCAGTTTTCTTACCTTTGGAATTATTCGTACCT
TTTATGGTAAATTTCAGCTTTGACATGTATTATGAGGAACGTACCAAAAACCGGTTTGTAACAAATCTGTAGAGAAGGTCTGAATCTATC
GTGTTTGCCTTTTCAGGTGCCATTTCTACTGCCTAATACAGTGCCATTTGCCTTGTGAAGACCCATAAACATTCATTGTGTTGAATGTAA
GATAGAGACTCTCCCTAGTCTTACTGATCTCAGTACCCCACAAATGATTAAGAATGATATGAAAACCAGCAGCTAAGGAACATCTTATTA
TTTAGTTGTAGCATATTCATAACAAGTGTCCTTCAAGGATAAACATATATTCTCTATTTGTATTTAGCAAGTAAAACTTGTGTTGACCTT
TAGTGCATTATATTCAGCTTTTAACAGTATTATGTATGTACTGGAAAGCAAAGAAATCTTAGAGTCTTGGACATTGTTTATTTGTGCAAC
AACTAGAAAGGAGCAATGAAGTTTATTTCAGTTGTATTTTTCCCTAAGCACAATCTGCAATAGTTTATGTATGACAGAGATAATTCAAAA
AGGAAAACTATATATAAAAGTTGTATATAAAGTTTGTCTCTGAAATATTTCTTTGAAGTTTTTAAAAAATCGACTCATGTTTAAAAACAA
AAACACATATTCAGAGCATTGGACTTTTTTAACTTGTTTTCATCTGTTTATCATGACTTTTTTATTTCTGGTGTAGAGTCCACATTATTT
AGTTTGTTGTACTTTTAAATTTCAAAGTTCAAATCTGAAGAATTAGCGTTTGTGATTTCGGGATACCATGCAGTGGTTTTAATCCCAGGA
AAAAAACTATCACCAAAAGTTCGTTTGATTCTCATTATGTAACTTTGTAGAACCATCCTTTCTAGATGGGTCCACCACAGTGAATTTGTA
ACTTTGAAGTCAGGATAGAATATCATTAGATTATCTGTGAGATAGCATTACTATGTTAGGACCAGCAGAGTTTGGGTTGGTAAAAATAAT
GTTTGCTCTATTACTGGGTTACAGACATTTCAGCATTTTTAGGTTGGTTTTAAATCACTAAAAATATTTATTCGGATTTGAAGGATTTAA
GTGCTAAAAATCAATCCATTTCTTGCCCTTCAATAATTGTCCATGCCTGCCTTTTGTTGTTTACATGCTCTTCTGCCCAGACTGTTAGTA
ATCTAGGGACCCCCTTTGGAGCTGATAAGTACAGTTCAGCCTTTTCTCCTCAAATATATAATGACTTTAACATTCCTAAGAATATAGGTA
TTTCTGAATGATTTAAATTTGAGGAATTTTAATACATAAAATACAATGTACAAACTTTCTGCCCACTCAGATCTCTTCTCCATCATGTAC
TTAGTATTTCCCATTAACCTACACACTGATTTTTATGCTACTCCTTGTAGAAACAAAATTCTGGTTTGACTCAGTTTTTGTGTTTATAAA
CTTTTGGAATGTGTACCCCGTTTATGTGAAGAATTATGACCTATCAGTCATAGCTAAATAGTGAACCTCAAAAGTGTTAACTTTTGACTA
TTCATGTGAGGTTTGGTATCTTGCATTTATGTACATGGCTGTAAATTATGTGCATTTACTCTGTATTTATGTTATCTAGCTGACTTTTAC


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FusionGenePPI for SLCO2A1_SLC25A36


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
SLCO2A1SLC25A36PTN, NME2P1, TRIM25


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for SLCO2A1_SLC25A36


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SLCO2A1_SLC25A36


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneSLCO2A1C3280800HYPERTROPHIC OSTEOARTHROPATHY, PRIMARY, AUTOSOMAL RECESSIVE, 24UNIPROT
HgeneSLCO2A1C0041755Adverse reaction to drug1CTD_human