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Fusion gene ID: 34643 |
FusionGeneSummary for SLC9A8_B4GALT5 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLC9A8_B4GALT5 | Fusion gene ID: 34643 | Hgene | Tgene | Gene symbol | SLC9A8 | B4GALT5 | Gene ID | 23315 | 9334 |
| Gene name | solute carrier family 9 member A8 | beta-1,4-galactosyltransferase 5 | |
| Synonyms | NHE-8|NHE8 | B4Gal-T5|BETA4-GALT-IV|beta4Gal-T5|beta4GalT-V|gt-V | |
| Cytomap | 20q13.13 | 20q13.13 | |
| Type of gene | protein-coding | protein-coding | |
| Description | sodium/hydrogen exchanger 8Na(+)/H(+) exchanger 8solute carrier family 9 (sodium/hydrogen exchanger)solute carrier family 9 (sodium/hydrogen exchanger), member 8solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 | beta-1,4-galactosyltransferase 5UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 5UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 5beta-1,4-GalT IIbeta-1,4-GalT I | |
| Modification date | 20180523 | 20180522 | |
| UniProtAcc | Q9Y2E8 | O43286 | |
| Ensembl transtripts involved in fusion gene | ENST00000417961, ENST00000361573, ENST00000541138, ENST00000539601, ENST00000490250, | ENST00000371711, | |
| Fusion gene scores | * DoF score | 4 X 3 X 4=48 | 7 X 6 X 3=126 |
| # samples | 4 | 7 | |
| ** MAII score | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/126*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SLC9A8 [Title/Abstract] AND B4GALT5 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-A1L0-01A | SLC9A8 | chr20 | 48431726 | + | B4GALT5 | chr20 | 48273239 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000417961 | ENST00000371711 | SLC9A8 | chr20 | 48431726 | + | B4GALT5 | chr20 | 48273239 | - |
| In-frame | ENST00000361573 | ENST00000371711 | SLC9A8 | chr20 | 48431726 | + | B4GALT5 | chr20 | 48273239 | - |
| 5UTR-3CDS | ENST00000541138 | ENST00000371711 | SLC9A8 | chr20 | 48431726 | + | B4GALT5 | chr20 | 48273239 | - |
| 5UTR-3CDS | ENST00000539601 | ENST00000371711 | SLC9A8 | chr20 | 48431726 | + | B4GALT5 | chr20 | 48273239 | - |
| intron-3CDS | ENST00000490250 | ENST00000371711 | SLC9A8 | chr20 | 48431726 | + | B4GALT5 | chr20 | 48273239 | - |
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FusionProtFeatures for SLC9A8_B4GALT5 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SLC9A8 | B4GALT5 |
| Involved in pH regulation to eliminate acids generatedby active metabolism or to counter adverse environmentalconditions. Major proton extruding system driven by the inwardsodium ion chemical gradient. Plays an important role in signaltransduction. {ECO:0000269|PubMed:15522866}. | Responsible for the synthesis of complex-type N-linkedoligosaccharides in many glycoproteins as well as the carbohydratemoieties of glycolipids. {ECO:0000269|PubMed:9435216}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >B4GALT5 | chr20:48431726 | chr20:48273239 | ENST00000371711 | - | 0 | 9 | 169_173 | 38 | 389 | Region | UDP-alpha-D-galactose binding |
| Tgene | >B4GALT5 | chr20:48431726 | chr20:48273239 | ENST00000371711 | - | 0 | 9 | 208_210 | 38 | 389 | Region | UDP-alpha-D-galactose binding |
| Tgene | >B4GALT5 | chr20:48431726 | chr20:48273239 | ENST00000371711 | - | 0 | 9 | 235_236 | 38 | 389 | Region | UDP-alpha-D-galactose binding |
| Tgene | >B4GALT5 | chr20:48431726 | chr20:48273239 | ENST00000371711 | - | 0 | 9 | 298_301 | 38 | 389 | Region | N-acetyl-D-glucosamine binding |
| Tgene | >B4GALT5 | chr20:48431726 | chr20:48273239 | ENST00000371711 | - | 0 | 9 | 329_330 | 38 | 389 | Region | UDP-alpha-D-galactose binding |
| Tgene | >B4GALT5 | chr20:48431726 | chr20:48273239 | ENST00000371711 | - | 0 | 9 | 36_388 | 38 | 389 | Topological domain | Lumenal |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000361573 | + | 2 | 16 | 123_143 | 69 | 582 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000361573 | + | 2 | 16 | 156_176 | 69 | 582 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000361573 | + | 2 | 16 | 191_211 | 69 | 582 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000361573 | + | 2 | 16 | 264_284 | 69 | 582 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000361573 | + | 2 | 16 | 311_331 | 69 | 582 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000361573 | + | 2 | 16 | 354_374 | 69 | 582 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000361573 | + | 2 | 16 | 379_399 | 69 | 582 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000361573 | + | 2 | 16 | 417_437 | 69 | 582 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000361573 | + | 2 | 16 | 451_471 | 69 | 582 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000361573 | + | 2 | 16 | 60_80 | 69 | 582 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000361573 | + | 2 | 16 | 84_104 | 69 | 582 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000417961 | + | 2 | 16 | 123_143 | 69 | 598 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000417961 | + | 2 | 16 | 156_176 | 69 | 598 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000417961 | + | 2 | 16 | 191_211 | 69 | 598 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000417961 | + | 2 | 16 | 264_284 | 69 | 598 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000417961 | + | 2 | 16 | 311_331 | 69 | 598 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000417961 | + | 2 | 16 | 354_374 | 69 | 598 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000417961 | + | 2 | 16 | 379_399 | 69 | 598 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000417961 | + | 2 | 16 | 417_437 | 69 | 598 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000417961 | + | 2 | 16 | 451_471 | 69 | 598 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000417961 | + | 2 | 16 | 60_80 | 69 | 598 | Transmembrane | Helical |
| Hgene | >SLC9A8 | chr20:48431726 | chr20:48273239 | ENST00000417961 | + | 2 | 16 | 84_104 | 69 | 598 | Transmembrane | Helical |
| Tgene | B4GALT5 | chr20:48431726 | chr20:48273239 | ENST00000371711 | - | 0 | 9 | 1_14 | 38 | 389 | Topological domain | Cytoplasmic |
| Tgene | B4GALT5 | chr20:48431726 | chr20:48273239 | ENST00000371711 | - | 0 | 9 | 15_35 | 38 | 389 | Transmembrane | Helical%3B Signal-anchor for type II membrane protein |
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FusionGeneSequence for SLC9A8_B4GALT5 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SLC9A8_ENST00000417961_chr20_48431726_+_B4GALT5_ENST00000371711_chr20_48273239_-_420aa MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGMTIFFSLLVLVNTYLFMMQAQGILIRDNVRT IGAQVYEQVLRSAYAKRNSSVNDSDYPLDLNHSETFLQTTTFLPEDFTYFANHTCPERLPSMKGPIDINMSEIGMDYIHELFSKDPTIKL GGHWKPSDCMPRWKVAILIPFRNRHEHLPVLFRHLLPMLQRQRLQFAFYVVEQVGTQPFNRAMLFNVGFQEAMKDLDWDCLIFHDVDHIP ESDRNYYGCGQMPRHFATKLDKYMYLLPYTEFFGGVSGLTVEQFRKINGFPNAFWGWGGEDDDLWNRVQNAGYSVSRPEGDTGKYKSIPH >In-frame_SLC9A8_ENST00000361573_chr20_48431726_+_B4GALT5_ENST00000371711_chr20_48273239_-_420aa MGEKMAEEERFPNTTHEGFNVTLHTTLVVTTKLVLPTPGKPILPVQTGEQAQQEEQSSGMTIFFSLLVLVNTYLFMMQAQGILIRDNVRT IGAQVYEQVLRSAYAKRNSSVNDSDYPLDLNHSETFLQTTTFLPEDFTYFANHTCPERLPSMKGPIDINMSEIGMDYIHELFSKDPTIKL GGHWKPSDCMPRWKVAILIPFRNRHEHLPVLFRHLLPMLQRQRLQFAFYVVEQVGTQPFNRAMLFNVGFQEAMKDLDWDCLIFHDVDHIP ESDRNYYGCGQMPRHFATKLDKYMYLLPYTEFFGGVSGLTVEQFRKINGFPNAFWGWGGEDDDLWNRVQNAGYSVSRPEGDTGKYKSIPH |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SLC9A8_ENST00000417961_chr20_48431726_+_B4GALT5_ENST00000371711_chr20_48273239_-_1260nt ATGGGGGAGAAGATGGCGGAAGAGGAGAGGTTCCCCAATACAACTCATGAGGGTTTCAATGTCACCCTCCACACCACCCTGGTTGTCACG ACGAAACTGGTGCTCCCGACCCCTGGCAAGCCCATCCTCCCCGTGCAGACAGGGGAGCAGGCCCAGCAAGAGGAGCAGTCCAGCGGCATG ACCATTTTCTTCAGCCTCCTTGTCCTAGTGAACACCTACCTCTTCATGATGCAAGCCCAAGGCATTCTGATCCGGGACAACGTGAGAACA ATCGGTGCTCAGGTTTATGAGCAGGTGCTTCGGAGTGCTTATGCCAAGAGGAACAGCAGTGTAAATGACTCAGATTATCCTCTTGACTTG AACCACAGTGAAACCTTCCTGCAAACTACAACATTTCTTCCTGAAGACTTCACCTACTTTGCAAACCATACCTGCCCTGAAAGACTCCCT TCCATGAAGGGCCCAATAGACATAAACATGAGTGAAATTGGAATGGATTACATTCATGAACTCTTCTCCAAAGACCCAACCATCAAGCTC GGAGGTCACTGGAAGCCTTCTGATTGCATGCCTCGGTGGAAGGTGGCGATCCTTATCCCCTTCCGGAACCGCCACGAGCACCTCCCAGTC CTGTTCAGACACCTGCTTCCCATGCTCCAGCGCCAGCGCTTGCAGTTTGCATTTTATGTGGTTGAACAAGTTGGTACCCAACCCTTTAAT CGAGCCATGCTTTTCAACGTTGGCTTTCAAGAGGCAATGAAAGACTTGGATTGGGACTGTTTGATTTTTCATGATGTAGATCACATACCG GAAAGTGATCGCAACTATTATGGATGTGGACAGATGCCGAGGCATTTTGCAACCAAATTGGATAAGTATATGTATCTGCTTCCTTATACC GAGTTCTTTGGCGGAGTGAGTGGCTTAACAGTGGAACAATTTCGGAAAATCAATGGCTTTCCTAATGCTTTCTGGGGTTGGGGTGGAGAA GATGACGACCTCTGGAACAGAGTACAGAATGCAGGCTATTCTGTGAGCCGGCCAGAGGGTGACACAGGAAAGTACAAGTCCATTCCTCAT CACCATCGAGGAGAAGTCCAGTTTCTTGGAAGGTATGCTCTGCTGAGGAAGTCAAAAGAACGGCAAGGGCTGGATGGCCTCAACAACCTG AACTACTTTGCAAACATCACATACGACGCCTTGTATAAAAACATAACTGTCAACCTGACACCCGAGCTGGCTCAGGTGAACGAGTACTGA >In-frame_SLC9A8_ENST00000361573_chr20_48431726_+_B4GALT5_ENST00000371711_chr20_48273239_-_1260nt ATGGGGGAGAAGATGGCGGAAGAGGAGAGGTTCCCCAATACAACTCATGAGGGTTTCAATGTCACCCTCCACACCACCCTGGTTGTCACG ACGAAACTGGTGCTCCCGACCCCTGGCAAGCCCATCCTCCCCGTGCAGACAGGGGAGCAGGCCCAGCAAGAGGAGCAGTCCAGCGGCATG ACCATTTTCTTCAGCCTCCTTGTCCTAGTGAACACCTACCTCTTCATGATGCAAGCCCAAGGCATTCTGATCCGGGACAACGTGAGAACA ATCGGTGCTCAGGTTTATGAGCAGGTGCTTCGGAGTGCTTATGCCAAGAGGAACAGCAGTGTAAATGACTCAGATTATCCTCTTGACTTG AACCACAGTGAAACCTTCCTGCAAACTACAACATTTCTTCCTGAAGACTTCACCTACTTTGCAAACCATACCTGCCCTGAAAGACTCCCT TCCATGAAGGGCCCAATAGACATAAACATGAGTGAAATTGGAATGGATTACATTCATGAACTCTTCTCCAAAGACCCAACCATCAAGCTC GGAGGTCACTGGAAGCCTTCTGATTGCATGCCTCGGTGGAAGGTGGCGATCCTTATCCCCTTCCGGAACCGCCACGAGCACCTCCCAGTC CTGTTCAGACACCTGCTTCCCATGCTCCAGCGCCAGCGCTTGCAGTTTGCATTTTATGTGGTTGAACAAGTTGGTACCCAACCCTTTAAT CGAGCCATGCTTTTCAACGTTGGCTTTCAAGAGGCAATGAAAGACTTGGATTGGGACTGTTTGATTTTTCATGATGTAGATCACATACCG GAAAGTGATCGCAACTATTATGGATGTGGACAGATGCCGAGGCATTTTGCAACCAAATTGGATAAGTATATGTATCTGCTTCCTTATACC GAGTTCTTTGGCGGAGTGAGTGGCTTAACAGTGGAACAATTTCGGAAAATCAATGGCTTTCCTAATGCTTTCTGGGGTTGGGGTGGAGAA GATGACGACCTCTGGAACAGAGTACAGAATGCAGGCTATTCTGTGAGCCGGCCAGAGGGTGACACAGGAAAGTACAAGTCCATTCCTCAT CACCATCGAGGAGAAGTCCAGTTTCTTGGAAGGTATGCTCTGCTGAGGAAGTCAAAAGAACGGCAAGGGCTGGATGGCCTCAACAACCTG AACTACTTTGCAAACATCACATACGACGCCTTGTATAAAAACATAACTGTCAACCTGACACCCGAGCTGGCTCAGGTGAACGAGTACTGA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SLC9A8_ENST00000417961_chr20_48431726_+_B4GALT5_ENST00000371711_chr20_48273239_-_4837nt CCGAAAGCCCCGGGAGAGACTAAGAAGCAATCCTCCCACGCGCTTTCTCCCACCCTCGGGCCACTGAGACGGAGGGACAGAGGGCCGCCC TCGCGCGGCCGAGGCCCCGCCTCCCGCTCGCCCGCCCGCGCCTCCAGCGGAAGCCGGAAGCAAAAGCGGGTCCTGCTAGCCCCGCGGCTC CGAACTCGGTGGTCCTGGAAGCTCCGCAGGATGGGGGAGAAGATGGCGGAAGAGGAGAGGTTCCCCAATACAACTCATGAGGGTTTCAAT GTCACCCTCCACACCACCCTGGTTGTCACGACGAAACTGGTGCTCCCGACCCCTGGCAAGCCCATCCTCCCCGTGCAGACAGGGGAGCAG GCCCAGCAAGAGGAGCAGTCCAGCGGCATGACCATTTTCTTCAGCCTCCTTGTCCTAGTGAACACCTACCTCTTCATGATGCAAGCCCAA GGCATTCTGATCCGGGACAACGTGAGAACAATCGGTGCTCAGGTTTATGAGCAGGTGCTTCGGAGTGCTTATGCCAAGAGGAACAGCAGT GTAAATGACTCAGATTATCCTCTTGACTTGAACCACAGTGAAACCTTCCTGCAAACTACAACATTTCTTCCTGAAGACTTCACCTACTTT GCAAACCATACCTGCCCTGAAAGACTCCCTTCCATGAAGGGCCCAATAGACATAAACATGAGTGAAATTGGAATGGATTACATTCATGAA CTCTTCTCCAAAGACCCAACCATCAAGCTCGGAGGTCACTGGAAGCCTTCTGATTGCATGCCTCGGTGGAAGGTGGCGATCCTTATCCCC TTCCGGAACCGCCACGAGCACCTCCCAGTCCTGTTCAGACACCTGCTTCCCATGCTCCAGCGCCAGCGCTTGCAGTTTGCATTTTATGTG GTTGAACAAGTTGGTACCCAACCCTTTAATCGAGCCATGCTTTTCAACGTTGGCTTTCAAGAGGCAATGAAAGACTTGGATTGGGACTGT TTGATTTTTCATGATGTAGATCACATACCGGAAAGTGATCGCAACTATTATGGATGTGGACAGATGCCGAGGCATTTTGCAACCAAATTG GATAAGTATATGTATCTGCTTCCTTATACCGAGTTCTTTGGCGGAGTGAGTGGCTTAACAGTGGAACAATTTCGGAAAATCAATGGCTTT CCTAATGCTTTCTGGGGTTGGGGTGGAGAAGATGACGACCTCTGGAACAGAGTACAGAATGCAGGCTATTCTGTGAGCCGGCCAGAGGGT GACACAGGAAAGTACAAGTCCATTCCTCATCACCATCGAGGAGAAGTCCAGTTTCTTGGAAGGTATGCTCTGCTGAGGAAGTCAAAAGAA CGGCAAGGGCTGGATGGCCTCAACAACCTGAACTACTTTGCAAACATCACATACGACGCCTTGTATAAAAACATAACTGTCAACCTGACA CCCGAGCTGGCTCAGGTGAACGAGTACTGAGAGGAGAGAATGTACGTTTGCTTTACCCACCGCCACCAAGAAAGCAGTCCGATGAGATTT TTTTTTGGAGGGGGGAGGGTCTACACAGCAAGAGAACAGAAATACTGTGTCTCATGAAGGATCACAGAGTTCAGGGGGAAAATGTGACAG CACACGCACAAACGCCTTCACTGGATCAGCCGCTGGAACTGAGGGAGTGAGCTTGGGGACTTCCTTCGTCAGCACTGGCTTTCTGTTTTC ACAAGACAGACGTCTGTCCCGCTGCTCTCTCCCCATCTCCTACCCCACATCCTGTCTTAGCCGCAGTCTCCAGAACCCATGATGAACTGT GATCTGCCGTGGTCCTGCCGTGGTCCTGCCGTGGAGCCTGTCCCTACACATGACCTTGGAGCCTCTTGGCCTTCAGAGCAGAGGCAAACC CACCACAGGGCAGCTGCGTTTTAGGAAGAGCAAATGAAACTCCACACCATTCTTCTAGATCTCTGGTGTTCTCTTTGGTTTCATTTTTTT AAAAAATTACCTTCTTTGGGTGGGGATTGAGGGTGGAGGGGAGGGTGTTTGGGAAAGATAAATAGACATAAATATATAACAATCACTTCT TGAAGAAGTATAATTGTAAATAAGCCATGTAAAATGCCTTTTTAAAATTTAATTTTCTAGCTGGCTCCAATTCAAATTGAGGATTTATGT ATTAGGCCACTTACTTGGTTGGCAAGTGCAGGAACTCAGTTAAAATGCAGTTGAAGAATGTCATCTCCCGAATTGCTGTCACTTTGGCGA GGGAGTGGATATAGGGCATGTCACAAAAGAACAAAATAACCCGACCTTTATTGCTGGGAGCTGGCTTCTGTCCCTTTCTTCCCCCCCCCA CGAGTCTTGCCCTTGACTTCTGCTCTGGATTCACTCTTCCCTGTCGGCCGCGCATGTGCTCATCCCACTCTCCGCTAAGCGGGAGGCTGC TGTTAGAGCAGGCTGCTTCCTGCCTAAAGCAGGCCCTTCGGGGCTCGCTGCACACACATCTCTGGCTCTCCAGGCTTCGTGTTCTGTCTT TTCATCAGCATGGCGGGGCGGGGGGCGGGGGGCGGGGGTGTGTATGGGAATCCCTCCCCCTCTTACTTTTTCTCTTGTGGAACTTGGCCA CAGTTTCTGAACAATGTGCCTACATTACCAGCTGGCTTCAGTGATTCCTCTGTGTCCCTTTTTGGTTTCTGGAAAGATTCTTTGTCAACA TTAGTAACTGATACATAGAACCAAGGAGCACTCAAATAGGGAGCCAGGAGCCAGGGAGCTGGTGACACTTGTGTGCTGTGGGGCAGCTGG GATCCAGGTAAGACCGGATTGAAGCTTTGAAATTAGACTAACAAAGCTCCAGACAGCAAGAGCCCAGGTGCACTGCTCACACCCCCACCT GCATTTTGAAGTCATATTATTTTTTGTTTTGTTTTTTAAGACGGTCTGGCTCTGTCGCCTAAGCTGGAGTGTGGTGGCACGATCACAGCT CACTGCAGCCTCCATCTCCTAGGCTCAAGCCATTTTCCCACCTCAGCCTCCCGAGTAGCTGGGACTACAGGTGCACACCACCACACCTGG CTAATTTTTTGTATTTTTAGTAGAGACAGGGGTTTCTTCCATGTTGCCCAGGCTGGTCTCGAACTCCTGGACTCAAGCAATCCGCCCACC TTGACTTCCCAAAGTGCTGGGATTATGGGCGGGTGTGAGCCATTGCGCCCAGCCTTGAAGTCATGTTCTAAATTGTATTTGAATTTGTGC CTCTTTGTTTTTCCCCAAACCAAAGCCCTCAAATTGTAGTCTCTGTCGGCTTCTGCAGAATTCTGGAAAATGCCAGTTTTCCTCCCCCGC CCTTGTTTTCCATAAAACATATTTATATATTGTGATGAGGAGTACTTTCTGAAGAGTACTTCGTATTTTTTTTTAATTGCCTTGTTTGCC TTCAACTTCCTTGATTTTCATAGTTTACATGGGTGTGTGTAGGGGTGTGTGTGTGTATGTGTGTGGGTTAGGGCTTTTTTCGTTGCATGT GATGGTTCTGTGGACATATGATCCCCACAAACTGTGGGAGTGATTGGCCAGGCCTTGTTTTGTTTGTTTGTTTGTTTGTGTTTTTGTTCT TTTGAAGAATAGAGTGGTATTTAGAAAATAAATTGCATTGCAAAGCTCTTATCGGCTCATATGAGAGAGCAGGTTCCTGCCCTTGAAAAT GCCGGTAAGCTATAGCATATGTTTTTTAAGACTTAAGCATTTCATGCTTTAAAATACCTTCACAAGTGAACATTACACACAGAAGTTCAT TTGGTTTTCCTTTGTTTTATGGTGCATATAGCAATAAAGACCCCCCTCCACCCTGCAACCCCCATCCCCCACCGGGCCTTTGTCCCTGCC TTGGCTTTTCTCCCCTTCTCATTCTCCTCTCCCCTTTCCTCACTGAAGGCTGTGAGTTGCTTTCAATGTGACAACACTATGATGTCATTT GGAAGGATTTGCCAGGACAGACTGATTCTGAGTCCTGGGTGCCGTATGTGTATGCGGCAGTGTTGTCAGGCGATCTTGTTTGAAGCTCTA TGTTGCCATAATTACCATCAAGTACACACTGTTGGCAAAAGGCTAACACCTGACTTTAGAAAATGCTGATTTGAGAACAAAAGGAAAGGT CTTTTTTCACTGCTTAAAGTGGGGTCACTTTGATACCTTTGCGGTCATGTCTGTGTCTGATGAGTGTAGAATCTCTGGATGTGCACTGTC AGTCATGTGTCCACCAGGCCTCGAATATCATATGGGAAATGTCATAGTTAAAAACGTACAGCCAGGCCCGTGTGCTGTTAATAGTGTGAA ATTGTCATGTTAAAAAAAAAAACAGGAACCAAATGTGACCTTGTGCATATATTGGTAGCTGAAAATCTTCAAGGCTACTGATGGGTGGCC CCTTAATCTTGTCTTTGATTGCTGTGTGCAGGGAAAGGTGTCCCCGTTTGTTCATGCTGTTTTGGGGGGTGGGGGGGTATTTGCAAGAAT ACTCATTTTGACATAATAGGTCCTCTTGTCAGAGATCCTCTACCACAGACATTAATAGCTGAGCAGGAGCCACATGGATTGATTGTATCC ACTCACCATTGACGATGGCATTGAGCGTAGCTAGCTTATTTCCATCACTACGTGTTTTTGAGCTTGCTCTTACGTTTTAAGAGGTGCCAG GGGTACATTTTTGCACTGAAATCTAAAGATGTTTTAAAAAACACTTTTCACAAAAATAGTCCTTTGTCATTACATTATTTACTCATGTGT >In-frame_SLC9A8_ENST00000361573_chr20_48431726_+_B4GALT5_ENST00000371711_chr20_48273239_-_4669nt GCCCCGCGGCTCCGAACTCGGTGGTCCTGGAAGCTCCGCAGGATGGGGGAGAAGATGGCGGAAGAGGAGAGGTTCCCCAATACAACTCAT GAGGGTTTCAATGTCACCCTCCACACCACCCTGGTTGTCACGACGAAACTGGTGCTCCCGACCCCTGGCAAGCCCATCCTCCCCGTGCAG ACAGGGGAGCAGGCCCAGCAAGAGGAGCAGTCCAGCGGCATGACCATTTTCTTCAGCCTCCTTGTCCTAGTGAACACCTACCTCTTCATG ATGCAAGCCCAAGGCATTCTGATCCGGGACAACGTGAGAACAATCGGTGCTCAGGTTTATGAGCAGGTGCTTCGGAGTGCTTATGCCAAG AGGAACAGCAGTGTAAATGACTCAGATTATCCTCTTGACTTGAACCACAGTGAAACCTTCCTGCAAACTACAACATTTCTTCCTGAAGAC TTCACCTACTTTGCAAACCATACCTGCCCTGAAAGACTCCCTTCCATGAAGGGCCCAATAGACATAAACATGAGTGAAATTGGAATGGAT TACATTCATGAACTCTTCTCCAAAGACCCAACCATCAAGCTCGGAGGTCACTGGAAGCCTTCTGATTGCATGCCTCGGTGGAAGGTGGCG ATCCTTATCCCCTTCCGGAACCGCCACGAGCACCTCCCAGTCCTGTTCAGACACCTGCTTCCCATGCTCCAGCGCCAGCGCTTGCAGTTT GCATTTTATGTGGTTGAACAAGTTGGTACCCAACCCTTTAATCGAGCCATGCTTTTCAACGTTGGCTTTCAAGAGGCAATGAAAGACTTG GATTGGGACTGTTTGATTTTTCATGATGTAGATCACATACCGGAAAGTGATCGCAACTATTATGGATGTGGACAGATGCCGAGGCATTTT GCAACCAAATTGGATAAGTATATGTATCTGCTTCCTTATACCGAGTTCTTTGGCGGAGTGAGTGGCTTAACAGTGGAACAATTTCGGAAA ATCAATGGCTTTCCTAATGCTTTCTGGGGTTGGGGTGGAGAAGATGACGACCTCTGGAACAGAGTACAGAATGCAGGCTATTCTGTGAGC CGGCCAGAGGGTGACACAGGAAAGTACAAGTCCATTCCTCATCACCATCGAGGAGAAGTCCAGTTTCTTGGAAGGTATGCTCTGCTGAGG AAGTCAAAAGAACGGCAAGGGCTGGATGGCCTCAACAACCTGAACTACTTTGCAAACATCACATACGACGCCTTGTATAAAAACATAACT GTCAACCTGACACCCGAGCTGGCTCAGGTGAACGAGTACTGAGAGGAGAGAATGTACGTTTGCTTTACCCACCGCCACCAAGAAAGCAGT CCGATGAGATTTTTTTTTGGAGGGGGGAGGGTCTACACAGCAAGAGAACAGAAATACTGTGTCTCATGAAGGATCACAGAGTTCAGGGGG AAAATGTGACAGCACACGCACAAACGCCTTCACTGGATCAGCCGCTGGAACTGAGGGAGTGAGCTTGGGGACTTCCTTCGTCAGCACTGG CTTTCTGTTTTCACAAGACAGACGTCTGTCCCGCTGCTCTCTCCCCATCTCCTACCCCACATCCTGTCTTAGCCGCAGTCTCCAGAACCC ATGATGAACTGTGATCTGCCGTGGTCCTGCCGTGGTCCTGCCGTGGAGCCTGTCCCTACACATGACCTTGGAGCCTCTTGGCCTTCAGAG CAGAGGCAAACCCACCACAGGGCAGCTGCGTTTTAGGAAGAGCAAATGAAACTCCACACCATTCTTCTAGATCTCTGGTGTTCTCTTTGG TTTCATTTTTTTAAAAAATTACCTTCTTTGGGTGGGGATTGAGGGTGGAGGGGAGGGTGTTTGGGAAAGATAAATAGACATAAATATATA ACAATCACTTCTTGAAGAAGTATAATTGTAAATAAGCCATGTAAAATGCCTTTTTAAAATTTAATTTTCTAGCTGGCTCCAATTCAAATT GAGGATTTATGTATTAGGCCACTTACTTGGTTGGCAAGTGCAGGAACTCAGTTAAAATGCAGTTGAAGAATGTCATCTCCCGAATTGCTG TCACTTTGGCGAGGGAGTGGATATAGGGCATGTCACAAAAGAACAAAATAACCCGACCTTTATTGCTGGGAGCTGGCTTCTGTCCCTTTC TTCCCCCCCCCACGAGTCTTGCCCTTGACTTCTGCTCTGGATTCACTCTTCCCTGTCGGCCGCGCATGTGCTCATCCCACTCTCCGCTAA GCGGGAGGCTGCTGTTAGAGCAGGCTGCTTCCTGCCTAAAGCAGGCCCTTCGGGGCTCGCTGCACACACATCTCTGGCTCTCCAGGCTTC GTGTTCTGTCTTTTCATCAGCATGGCGGGGCGGGGGGCGGGGGGCGGGGGTGTGTATGGGAATCCCTCCCCCTCTTACTTTTTCTCTTGT GGAACTTGGCCACAGTTTCTGAACAATGTGCCTACATTACCAGCTGGCTTCAGTGATTCCTCTGTGTCCCTTTTTGGTTTCTGGAAAGAT TCTTTGTCAACATTAGTAACTGATACATAGAACCAAGGAGCACTCAAATAGGGAGCCAGGAGCCAGGGAGCTGGTGACACTTGTGTGCTG TGGGGCAGCTGGGATCCAGGTAAGACCGGATTGAAGCTTTGAAATTAGACTAACAAAGCTCCAGACAGCAAGAGCCCAGGTGCACTGCTC ACACCCCCACCTGCATTTTGAAGTCATATTATTTTTTGTTTTGTTTTTTAAGACGGTCTGGCTCTGTCGCCTAAGCTGGAGTGTGGTGGC ACGATCACAGCTCACTGCAGCCTCCATCTCCTAGGCTCAAGCCATTTTCCCACCTCAGCCTCCCGAGTAGCTGGGACTACAGGTGCACAC CACCACACCTGGCTAATTTTTTGTATTTTTAGTAGAGACAGGGGTTTCTTCCATGTTGCCCAGGCTGGTCTCGAACTCCTGGACTCAAGC AATCCGCCCACCTTGACTTCCCAAAGTGCTGGGATTATGGGCGGGTGTGAGCCATTGCGCCCAGCCTTGAAGTCATGTTCTAAATTGTAT TTGAATTTGTGCCTCTTTGTTTTTCCCCAAACCAAAGCCCTCAAATTGTAGTCTCTGTCGGCTTCTGCAGAATTCTGGAAAATGCCAGTT TTCCTCCCCCGCCCTTGTTTTCCATAAAACATATTTATATATTGTGATGAGGAGTACTTTCTGAAGAGTACTTCGTATTTTTTTTTAATT GCCTTGTTTGCCTTCAACTTCCTTGATTTTCATAGTTTACATGGGTGTGTGTAGGGGTGTGTGTGTGTATGTGTGTGGGTTAGGGCTTTT TTCGTTGCATGTGATGGTTCTGTGGACATATGATCCCCACAAACTGTGGGAGTGATTGGCCAGGCCTTGTTTTGTTTGTTTGTTTGTTTG TGTTTTTGTTCTTTTGAAGAATAGAGTGGTATTTAGAAAATAAATTGCATTGCAAAGCTCTTATCGGCTCATATGAGAGAGCAGGTTCCT GCCCTTGAAAATGCCGGTAAGCTATAGCATATGTTTTTTAAGACTTAAGCATTTCATGCTTTAAAATACCTTCACAAGTGAACATTACAC ACAGAAGTTCATTTGGTTTTCCTTTGTTTTATGGTGCATATAGCAATAAAGACCCCCCTCCACCCTGCAACCCCCATCCCCCACCGGGCC TTTGTCCCTGCCTTGGCTTTTCTCCCCTTCTCATTCTCCTCTCCCCTTTCCTCACTGAAGGCTGTGAGTTGCTTTCAATGTGACAACACT ATGATGTCATTTGGAAGGATTTGCCAGGACAGACTGATTCTGAGTCCTGGGTGCCGTATGTGTATGCGGCAGTGTTGTCAGGCGATCTTG TTTGAAGCTCTATGTTGCCATAATTACCATCAAGTACACACTGTTGGCAAAAGGCTAACACCTGACTTTAGAAAATGCTGATTTGAGAAC AAAAGGAAAGGTCTTTTTTCACTGCTTAAAGTGGGGTCACTTTGATACCTTTGCGGTCATGTCTGTGTCTGATGAGTGTAGAATCTCTGG ATGTGCACTGTCAGTCATGTGTCCACCAGGCCTCGAATATCATATGGGAAATGTCATAGTTAAAAACGTACAGCCAGGCCCGTGTGCTGT TAATAGTGTGAAATTGTCATGTTAAAAAAAAAAACAGGAACCAAATGTGACCTTGTGCATATATTGGTAGCTGAAAATCTTCAAGGCTAC TGATGGGTGGCCCCTTAATCTTGTCTTTGATTGCTGTGTGCAGGGAAAGGTGTCCCCGTTTGTTCATGCTGTTTTGGGGGGTGGGGGGGT ATTTGCAAGAATACTCATTTTGACATAATAGGTCCTCTTGTCAGAGATCCTCTACCACAGACATTAATAGCTGAGCAGGAGCCACATGGA TTGATTGTATCCACTCACCATTGACGATGGCATTGAGCGTAGCTAGCTTATTTCCATCACTACGTGTTTTTGAGCTTGCTCTTACGTTTT AAGAGGTGCCAGGGGTACATTTTTGCACTGAAATCTAAAGATGTTTTAAAAAACACTTTTCACAAAAATAGTCCTTTGTCATTACATTAT |
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FusionGenePPI for SLC9A8_B4GALT5 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SLC9A8 | ALB, KRAS | B4GALT5 | ELAVL1, HLA-DPA1, NXPH2, IL20RB, GINM1, TNF, LIPH, IL27RA, FCGRT, SLC39A9, KIAA1467, IL13RA2, SYT12, KERA, GABRG2, CRP, HSPA13, MGAT4C, AVP, TPCN2, TRIM25 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SLC9A8_B4GALT5 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SLC9A8_B4GALT5 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | SLC9A8 | C0497327 | Dementia | 1 | CTD_human |
| Tgene | B4GALT5 | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Tgene | B4GALT5 | C3495559 | Juvenile arthritis | 1 | CTD_human |
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