|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 34296 |
FusionGeneSummary for SLC2A13_ARHGDIB |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SLC2A13_ARHGDIB | Fusion gene ID: 34296 | Hgene | Tgene | Gene symbol | SLC2A13 | ARHGDIB | Gene ID | 114134 | 397 |
| Gene name | solute carrier family 2 member 13 | Rho GDP dissociation inhibitor beta | |
| Synonyms | HMIT | D4|GDIA2|GDID4|LYGDI|Ly-GDI|RAP1GN1|RhoGDI2 | |
| Cytomap | 12q12 | 12p12.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | proton myo-inositol cotransporterH(+)-myo-inositol symporterh(+)-myo-inositol cotransporterproton (H+) myo-inositol symportersolute carrier family 2 (facilitated glucose transporter), member 13 | rho GDP-dissociation inhibitor 2Rho GDI 2Rho GDP dissociation inhibitor (GDI) betarho-GDI beta | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q96QE2 | P52566 | |
| Ensembl transtripts involved in fusion gene | ENST00000280871, ENST00000380858, | ENST00000228945, ENST00000541644, ENST00000539131, ENST00000541546, | |
| Fusion gene scores | * DoF score | 9 X 5 X 7=315 | 4 X 4 X 3=48 |
| # samples | 7 | 4 | |
| ** MAII score | log2(7/315*10)=-2.16992500144231 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SLC2A13 [Title/Abstract] AND ARHGDIB [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ARHGDIB | GO:0035023 | regulation of Rho protein signal transduction | 7512369 |
| Tgene | ARHGDIB | GO:1901164 | negative regulation of trophoblast cell migration | 24554735 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | SARC | TCGA-DX-A240-01A | SLC2A13 | chr12 | 40422103 | - | ARHGDIB | chr12 | 15100883 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000280871 | ENST00000228945 | SLC2A13 | chr12 | 40422103 | - | ARHGDIB | chr12 | 15100883 | - |
| In-frame | ENST00000280871 | ENST00000541644 | SLC2A13 | chr12 | 40422103 | - | ARHGDIB | chr12 | 15100883 | - |
| 5CDS-5UTR | ENST00000280871 | ENST00000539131 | SLC2A13 | chr12 | 40422103 | - | ARHGDIB | chr12 | 15100883 | - |
| 5CDS-5UTR | ENST00000280871 | ENST00000541546 | SLC2A13 | chr12 | 40422103 | - | ARHGDIB | chr12 | 15100883 | - |
| In-frame | ENST00000380858 | ENST00000228945 | SLC2A13 | chr12 | 40422103 | - | ARHGDIB | chr12 | 15100883 | - |
| In-frame | ENST00000380858 | ENST00000541644 | SLC2A13 | chr12 | 40422103 | - | ARHGDIB | chr12 | 15100883 | - |
| 5CDS-5UTR | ENST00000380858 | ENST00000539131 | SLC2A13 | chr12 | 40422103 | - | ARHGDIB | chr12 | 15100883 | - |
| 5CDS-5UTR | ENST00000380858 | ENST00000541546 | SLC2A13 | chr12 | 40422103 | - | ARHGDIB | chr12 | 15100883 | - |
Top |
FusionProtFeatures for SLC2A13_ARHGDIB |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SLC2A13 | ARHGDIB |
| H(+)-myo-inositol cotransporter. Can also transportrelated stereoisomers. {ECO:0000269|PubMed:11500374}. | Regulates the GDP/GTP exchange reaction of the Rhoproteins by inhibiting the dissociation of GDP from them, and thesubsequent binding of GTP to them (PubMed:8356058,PubMed:7512369). Regulates reorganization of the actincytoskeleton mediated by Rho family members (PubMed:8262133).{ECO:0000269|PubMed:7512369, ECO:0000269|PubMed:8262133,ECO:0000269|PubMed:8356058}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 147_148 | 308 | 649 | Topological domain | Cytoplasmic |
| Hgene | SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 170_178 | 308 | 649 | Topological domain | Extracellular |
| Hgene | SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 1_76 | 308 | 649 | Topological domain | Cytoplasmic |
| Hgene | SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 200_212 | 308 | 649 | Topological domain | Cytoplasmic |
| Hgene | SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 234_239 | 308 | 649 | Topological domain | Extracellular |
| Hgene | SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 98_125 | 308 | 649 | Topological domain | Extracellular |
| Hgene | SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 126_146 | 308 | 649 | Transmembrane | Helical%3B Name%3D2 |
| Hgene | SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 149_169 | 308 | 649 | Transmembrane | Helical%3B Name%3D3 |
| Hgene | SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 179_199 | 308 | 649 | Transmembrane | Helical%3B Name%3D4 |
| Hgene | SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 213_233 | 308 | 649 | Transmembrane | Helical%3B Name%3D5 |
| Hgene | SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 240_260 | 308 | 649 | Transmembrane | Helical%3B Name%3D6 |
| Hgene | SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 77_97 | 308 | 649 | Transmembrane | Helical%3B Name%3D1 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 261_324 | 308 | 649 | Topological domain | Cytoplasmic |
| Hgene | >SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 346_363 | 308 | 649 | Topological domain | Extracellular |
| Hgene | >SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 385_393 | 308 | 649 | Topological domain | Cytoplasmic |
| Hgene | >SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 415_508 | 308 | 649 | Topological domain | Extracellular |
| Hgene | >SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 530_549 | 308 | 649 | Topological domain | Cytoplasmic |
| Hgene | >SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 571_573 | 308 | 649 | Topological domain | Extracellular |
| Hgene | >SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 595_648 | 308 | 649 | Topological domain | Cytoplasmic |
| Hgene | >SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 325_345 | 308 | 649 | Transmembrane | Helical%3B Name%3D7 |
| Hgene | >SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 364_384 | 308 | 649 | Transmembrane | Helical%3B Name%3D8 |
| Hgene | >SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 394_414 | 308 | 649 | Transmembrane | Helical%3B Name%3D9 |
| Hgene | >SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 509_529 | 308 | 649 | Transmembrane | Helical%3B Name%3D10 |
| Hgene | >SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 550_570 | 308 | 649 | Transmembrane | Helical%3B Name%3D11 |
| Hgene | >SLC2A13 | chr12:40422103 | chr12:15100883 | ENST00000280871 | - | 3 | 10 | 574_594 | 308 | 649 | Transmembrane | Helical%3B Name%3D12 |
Top |
FusionGeneSequence for SLC2A13_ARHGDIB |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SLC2A13_ENST00000280871_chr12_40422103_-_ARHGDIB_ENST00000228945_chr12_15100883_-_422aa MSRKASENVEYTLRSLSSLMGERRRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSAL GGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLV VGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKG QTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSGDLEALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKAT >In-frame_SLC2A13_ENST00000280871_chr12_40422103_-_ARHGDIB_ENST00000541644_chr12_15100883_-_422aa MSRKASENVEYTLRSLSSLMGERRRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSAL GGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLV VGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKG QTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSGDLEALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKAT >In-frame_SLC2A13_ENST00000380858_chr12_40422103_-_ARHGDIB_ENST00000228945_chr12_15100883_-_422aa MSRKASENVEYTLRSLSSLMGERRRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSAL GGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLV VGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKG QTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSGDLEALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKAT >In-frame_SLC2A13_ENST00000380858_chr12_40422103_-_ARHGDIB_ENST00000541644_chr12_15100883_-_422aa MSRKASENVEYTLRSLSSLMGERRRKQPEPDAASAAGECSLLAAAESSTSLQSAGAGGGGVGDLERAARRQFQQDETPAFVYVVAVFSAL GGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGGALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLV VGLGIGIASMTVPVYIAEVSPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFLPESPRWLIQKG QTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSGDLEALKKETIVLKEGSEYRVKIHFKVNRDIVSGLKYVQHTYRTGVKVDKAT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SLC2A13_ENST00000280871_chr12_40422103_-_ARHGDIB_ENST00000228945_chr12_15100883_-_1266nt ATGTCCCGCAAGGCAAGCGAGAATGTGGAGTACACGCTGCGGAGCCTGAGCAGCCTGATGGGCGAGCGGCGCAGGAAGCAGCCGGAGCCG GACGCGGCGAGCGCGGCCGGGGAGTGCAGCCTCCTGGCTGCCGCCGAATCGAGCACCAGCCTGCAGAGCGCGGGCGCGGGCGGCGGCGGC GTCGGGGACCTGGAGCGCGCGGCGCGGCGGCAGTTCCAGCAGGACGAGACCCCCGCCTTCGTGTACGTGGTGGCCGTCTTCTCCGCGCTG GGCGGCTTCCTGTTTGGCTATGACACCGGGGTGGTGTCAGGGGCCATGCTGCTGCTCAAGCGGCAGCTCAGTCTGGACGCGCTGTGGCAG GAGCTGCTGGTGTCCAGCACGGTGGGGGCGGCTGCCGTCTCGGCGCTGGCCGGAGGCGCCCTCAACGGCGTCTTCGGCCGCCGCGCTGCC ATCCTCCTGGCCAGTGCCCTCTTCACCGCCGGCTCCGCGGTGCTGGCTGCGGCCAACAACAAGGAGACACTGCTCGCCGGCCGCCTGGTC GTGGGACTCGGCATCGGCATTGCTTCTATGACAGTGCCAGTGTACATTGCGGAGGTCTCACCACCCAATTTAAGAGGCCGATTAGTCACC ATTAATACCCTCTTCATCACAGGAGGGCAGTTCTTTGCAAGTGTTGTTGATGGAGCCTTCAGTTATCTCCAGAAGGATGGATGGAGGTAC ATGTTGGGACTTGCAGCAGTTCCGGCGGTTATACAGTTTTTTGGCTTTCTCTTTTTGCCTGAAAGCCCTCGATGGCTTATTCAGAAAGGA CAGACTCAGAAGGCCCGTAGAATTTTATCTCAGATGCGTGGTAACCAGACCATTGATGAGGAATATGATAGCATCAAAAACAACATTGAA GAGGAGGAAAAAGAGGTTGGCTCAGGAGATCTGGAAGCCCTCAAAAAGGAAACCATTGTGTTAAAGGAAGGTTCTGAATATAGAGTCAAA ATTCACTTCAAAGTGAACAGGGATATTGTGTCAGGCCTGAAATACGTTCAGCACACCTACAGGACTGGGGTGAAAGTGGATAAAGCAACA TTTATGGTTGGCAGCTATGGACCTCGGCCTGAGGAGTATGAGTTCCTCACTCCAGTTGAGGAGGCTCCCAAGGGCATGCTGGCGCGAGGC ACGTACCACAACAAGTCCTTCTTCACCGACGATGACAAGCAAGACCACCTCAGCTGGGAGTGGAACCTGTCGATTAAGAAGGAGTGGACA >In-frame_SLC2A13_ENST00000280871_chr12_40422103_-_ARHGDIB_ENST00000541644_chr12_15100883_-_1266nt ATGTCCCGCAAGGCAAGCGAGAATGTGGAGTACACGCTGCGGAGCCTGAGCAGCCTGATGGGCGAGCGGCGCAGGAAGCAGCCGGAGCCG GACGCGGCGAGCGCGGCCGGGGAGTGCAGCCTCCTGGCTGCCGCCGAATCGAGCACCAGCCTGCAGAGCGCGGGCGCGGGCGGCGGCGGC GTCGGGGACCTGGAGCGCGCGGCGCGGCGGCAGTTCCAGCAGGACGAGACCCCCGCCTTCGTGTACGTGGTGGCCGTCTTCTCCGCGCTG GGCGGCTTCCTGTTTGGCTATGACACCGGGGTGGTGTCAGGGGCCATGCTGCTGCTCAAGCGGCAGCTCAGTCTGGACGCGCTGTGGCAG GAGCTGCTGGTGTCCAGCACGGTGGGGGCGGCTGCCGTCTCGGCGCTGGCCGGAGGCGCCCTCAACGGCGTCTTCGGCCGCCGCGCTGCC ATCCTCCTGGCCAGTGCCCTCTTCACCGCCGGCTCCGCGGTGCTGGCTGCGGCCAACAACAAGGAGACACTGCTCGCCGGCCGCCTGGTC GTGGGACTCGGCATCGGCATTGCTTCTATGACAGTGCCAGTGTACATTGCGGAGGTCTCACCACCCAATTTAAGAGGCCGATTAGTCACC ATTAATACCCTCTTCATCACAGGAGGGCAGTTCTTTGCAAGTGTTGTTGATGGAGCCTTCAGTTATCTCCAGAAGGATGGATGGAGGTAC ATGTTGGGACTTGCAGCAGTTCCGGCGGTTATACAGTTTTTTGGCTTTCTCTTTTTGCCTGAAAGCCCTCGATGGCTTATTCAGAAAGGA CAGACTCAGAAGGCCCGTAGAATTTTATCTCAGATGCGTGGTAACCAGACCATTGATGAGGAATATGATAGCATCAAAAACAACATTGAA GAGGAGGAAAAAGAGGTTGGCTCAGGAGATCTGGAAGCCCTCAAAAAGGAAACCATTGTGTTAAAGGAAGGTTCTGAATATAGAGTCAAA ATTCACTTCAAAGTGAACAGGGATATTGTGTCAGGCCTGAAATACGTTCAGCACACCTACAGGACTGGGGTGAAAGTGGATAAAGCAACA TTTATGGTTGGCAGCTATGGACCTCGGCCTGAGGAGTATGAGTTCCTCACTCCAGTTGAGGAGGCTCCCAAGGGCATGCTGGCGCGAGGC ACGTACCACAACAAGTCCTTCTTCACCGACGATGACAAGCAAGACCACCTCAGCTGGGAGTGGAACCTGTCGATTAAGAAGGAGTGGACA >In-frame_SLC2A13_ENST00000380858_chr12_40422103_-_ARHGDIB_ENST00000228945_chr12_15100883_-_1266nt ATGTCCCGCAAGGCAAGCGAGAATGTGGAGTACACGCTGCGGAGCCTGAGCAGCCTGATGGGCGAGCGGCGCAGGAAGCAGCCGGAGCCG GACGCGGCGAGCGCGGCCGGGGAGTGCAGCCTCCTGGCTGCCGCCGAATCGAGCACCAGCCTGCAGAGCGCGGGCGCGGGCGGCGGCGGC GTCGGGGACCTGGAGCGCGCGGCGCGGCGGCAGTTCCAGCAGGACGAGACCCCCGCCTTCGTGTACGTGGTGGCCGTCTTCTCCGCGCTG GGCGGCTTCCTGTTTGGCTATGACACCGGGGTGGTGTCAGGGGCCATGCTGCTGCTCAAGCGGCAGCTCAGTCTGGACGCGCTGTGGCAG GAGCTGCTGGTGTCCAGCACGGTGGGGGCGGCTGCCGTCTCGGCGCTGGCCGGAGGCGCCCTCAACGGCGTCTTCGGCCGCCGCGCTGCC ATCCTCCTGGCCAGTGCCCTCTTCACCGCCGGCTCCGCGGTGCTGGCTGCGGCCAACAACAAGGAGACACTGCTCGCCGGCCGCCTGGTC GTGGGACTCGGCATCGGCATTGCTTCTATGACAGTGCCAGTGTACATTGCGGAGGTCTCACCACCCAATTTAAGAGGCCGATTAGTCACC ATTAATACCCTCTTCATCACAGGAGGGCAGTTCTTTGCAAGTGTTGTTGATGGAGCCTTCAGTTATCTCCAGAAGGATGGATGGAGGTAC ATGTTGGGACTTGCAGCAGTTCCGGCGGTTATACAGTTTTTTGGCTTTCTCTTTTTGCCTGAAAGCCCTCGATGGCTTATTCAGAAAGGA CAGACTCAGAAGGCCCGTAGAATTTTATCTCAGATGCGTGGTAACCAGACCATTGATGAGGAATATGATAGCATCAAAAACAACATTGAA GAGGAGGAAAAAGAGGTTGGCTCAGGAGATCTGGAAGCCCTCAAAAAGGAAACCATTGTGTTAAAGGAAGGTTCTGAATATAGAGTCAAA ATTCACTTCAAAGTGAACAGGGATATTGTGTCAGGCCTGAAATACGTTCAGCACACCTACAGGACTGGGGTGAAAGTGGATAAAGCAACA TTTATGGTTGGCAGCTATGGACCTCGGCCTGAGGAGTATGAGTTCCTCACTCCAGTTGAGGAGGCTCCCAAGGGCATGCTGGCGCGAGGC ACGTACCACAACAAGTCCTTCTTCACCGACGATGACAAGCAAGACCACCTCAGCTGGGAGTGGAACCTGTCGATTAAGAAGGAGTGGACA >In-frame_SLC2A13_ENST00000380858_chr12_40422103_-_ARHGDIB_ENST00000541644_chr12_15100883_-_1266nt ATGTCCCGCAAGGCAAGCGAGAATGTGGAGTACACGCTGCGGAGCCTGAGCAGCCTGATGGGCGAGCGGCGCAGGAAGCAGCCGGAGCCG GACGCGGCGAGCGCGGCCGGGGAGTGCAGCCTCCTGGCTGCCGCCGAATCGAGCACCAGCCTGCAGAGCGCGGGCGCGGGCGGCGGCGGC GTCGGGGACCTGGAGCGCGCGGCGCGGCGGCAGTTCCAGCAGGACGAGACCCCCGCCTTCGTGTACGTGGTGGCCGTCTTCTCCGCGCTG GGCGGCTTCCTGTTTGGCTATGACACCGGGGTGGTGTCAGGGGCCATGCTGCTGCTCAAGCGGCAGCTCAGTCTGGACGCGCTGTGGCAG GAGCTGCTGGTGTCCAGCACGGTGGGGGCGGCTGCCGTCTCGGCGCTGGCCGGAGGCGCCCTCAACGGCGTCTTCGGCCGCCGCGCTGCC ATCCTCCTGGCCAGTGCCCTCTTCACCGCCGGCTCCGCGGTGCTGGCTGCGGCCAACAACAAGGAGACACTGCTCGCCGGCCGCCTGGTC GTGGGACTCGGCATCGGCATTGCTTCTATGACAGTGCCAGTGTACATTGCGGAGGTCTCACCACCCAATTTAAGAGGCCGATTAGTCACC ATTAATACCCTCTTCATCACAGGAGGGCAGTTCTTTGCAAGTGTTGTTGATGGAGCCTTCAGTTATCTCCAGAAGGATGGATGGAGGTAC ATGTTGGGACTTGCAGCAGTTCCGGCGGTTATACAGTTTTTTGGCTTTCTCTTTTTGCCTGAAAGCCCTCGATGGCTTATTCAGAAAGGA CAGACTCAGAAGGCCCGTAGAATTTTATCTCAGATGCGTGGTAACCAGACCATTGATGAGGAATATGATAGCATCAAAAACAACATTGAA GAGGAGGAAAAAGAGGTTGGCTCAGGAGATCTGGAAGCCCTCAAAAAGGAAACCATTGTGTTAAAGGAAGGTTCTGAATATAGAGTCAAA ATTCACTTCAAAGTGAACAGGGATATTGTGTCAGGCCTGAAATACGTTCAGCACACCTACAGGACTGGGGTGAAAGTGGATAAAGCAACA TTTATGGTTGGCAGCTATGGACCTCGGCCTGAGGAGTATGAGTTCCTCACTCCAGTTGAGGAGGCTCCCAAGGGCATGCTGGCGCGAGGC ACGTACCACAACAAGTCCTTCTTCACCGACGATGACAAGCAAGACCACCTCAGCTGGGAGTGGAACCTGTCGATTAAGAAGGAGTGGACA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SLC2A13_ENST00000280871_chr12_40422103_-_ARHGDIB_ENST00000228945_chr12_15100883_-_1822nt CTGCCGGCCCGCGGAGCCGCGTCCCCCCGGGCAGCCCCGGGCCCCTGCCCTATGTCCCGCAAGGCAAGCGAGAATGTGGAGTACACGCTG CGGAGCCTGAGCAGCCTGATGGGCGAGCGGCGCAGGAAGCAGCCGGAGCCGGACGCGGCGAGCGCGGCCGGGGAGTGCAGCCTCCTGGCT GCCGCCGAATCGAGCACCAGCCTGCAGAGCGCGGGCGCGGGCGGCGGCGGCGTCGGGGACCTGGAGCGCGCGGCGCGGCGGCAGTTCCAG CAGGACGAGACCCCCGCCTTCGTGTACGTGGTGGCCGTCTTCTCCGCGCTGGGCGGCTTCCTGTTTGGCTATGACACCGGGGTGGTGTCA GGGGCCATGCTGCTGCTCAAGCGGCAGCTCAGTCTGGACGCGCTGTGGCAGGAGCTGCTGGTGTCCAGCACGGTGGGGGCGGCTGCCGTC TCGGCGCTGGCCGGAGGCGCCCTCAACGGCGTCTTCGGCCGCCGCGCTGCCATCCTCCTGGCCAGTGCCCTCTTCACCGCCGGCTCCGCG GTGCTGGCTGCGGCCAACAACAAGGAGACACTGCTCGCCGGCCGCCTGGTCGTGGGACTCGGCATCGGCATTGCTTCTATGACAGTGCCA GTGTACATTGCGGAGGTCTCACCACCCAATTTAAGAGGCCGATTAGTCACCATTAATACCCTCTTCATCACAGGAGGGCAGTTCTTTGCA AGTGTTGTTGATGGAGCCTTCAGTTATCTCCAGAAGGATGGATGGAGGTACATGTTGGGACTTGCAGCAGTTCCGGCGGTTATACAGTTT TTTGGCTTTCTCTTTTTGCCTGAAAGCCCTCGATGGCTTATTCAGAAAGGACAGACTCAGAAGGCCCGTAGAATTTTATCTCAGATGCGT GGTAACCAGACCATTGATGAGGAATATGATAGCATCAAAAACAACATTGAAGAGGAGGAAAAAGAGGTTGGCTCAGGAGATCTGGAAGCC CTCAAAAAGGAAACCATTGTGTTAAAGGAAGGTTCTGAATATAGAGTCAAAATTCACTTCAAAGTGAACAGGGATATTGTGTCAGGCCTG AAATACGTTCAGCACACCTACAGGACTGGGGTGAAAGTGGATAAAGCAACATTTATGGTTGGCAGCTATGGACCTCGGCCTGAGGAGTAT GAGTTCCTCACTCCAGTTGAGGAGGCTCCCAAGGGCATGCTGGCGCGAGGCACGTACCACAACAAGTCCTTCTTCACCGACGATGACAAG CAAGACCACCTCAGCTGGGAGTGGAACCTGTCGATTAAGAAGGAGTGGACAGAATGAATGCATCCACCCCTTTCCCCACCCTTGCCACCT GGAAGAATTCTCTCAGGCGTGTTCAGCACCCTGTCCCTCCTCCCTGTCCACAGCTGGGTCCCTCTTCAACACTGCCACATTTCCTTATTG ATGCATCTTTTCCCACCCTGTCACTCAACGTGGTCCCTAGAACAAGAGGCTTAAAACCGGGCTTTCACCCAACCTGCTCCCTCTGATCCT CCATCAGGGCCAGATCTTCCACGTCTCCATCTCAGTACACAATCATTTAATATTTCCCTGTCTTACCCCTATTCAAGCAACTAGAGGCCA GAAAATGGGCAAATTATCACTAACAGGTCTTTGACTCAGGTTCCAGTAGTTCATTCTAATGCCTAGATTCTTTTGTGGTTGTTGCTGGCC CAATGAGTCCCTAGTCACATCCCCTGCCAGAGGGAGTTCTTCTTTTGTGAGAGACACTGTAAACGACACAAGAGAACAAGAATAAAACAA >In-frame_SLC2A13_ENST00000280871_chr12_40422103_-_ARHGDIB_ENST00000541644_chr12_15100883_-_1509nt CTGCCGGCCCGCGGAGCCGCGTCCCCCCGGGCAGCCCCGGGCCCCTGCCCTATGTCCCGCAAGGCAAGCGAGAATGTGGAGTACACGCTG CGGAGCCTGAGCAGCCTGATGGGCGAGCGGCGCAGGAAGCAGCCGGAGCCGGACGCGGCGAGCGCGGCCGGGGAGTGCAGCCTCCTGGCT GCCGCCGAATCGAGCACCAGCCTGCAGAGCGCGGGCGCGGGCGGCGGCGGCGTCGGGGACCTGGAGCGCGCGGCGCGGCGGCAGTTCCAG CAGGACGAGACCCCCGCCTTCGTGTACGTGGTGGCCGTCTTCTCCGCGCTGGGCGGCTTCCTGTTTGGCTATGACACCGGGGTGGTGTCA GGGGCCATGCTGCTGCTCAAGCGGCAGCTCAGTCTGGACGCGCTGTGGCAGGAGCTGCTGGTGTCCAGCACGGTGGGGGCGGCTGCCGTC TCGGCGCTGGCCGGAGGCGCCCTCAACGGCGTCTTCGGCCGCCGCGCTGCCATCCTCCTGGCCAGTGCCCTCTTCACCGCCGGCTCCGCG GTGCTGGCTGCGGCCAACAACAAGGAGACACTGCTCGCCGGCCGCCTGGTCGTGGGACTCGGCATCGGCATTGCTTCTATGACAGTGCCA GTGTACATTGCGGAGGTCTCACCACCCAATTTAAGAGGCCGATTAGTCACCATTAATACCCTCTTCATCACAGGAGGGCAGTTCTTTGCA AGTGTTGTTGATGGAGCCTTCAGTTATCTCCAGAAGGATGGATGGAGGTACATGTTGGGACTTGCAGCAGTTCCGGCGGTTATACAGTTT TTTGGCTTTCTCTTTTTGCCTGAAAGCCCTCGATGGCTTATTCAGAAAGGACAGACTCAGAAGGCCCGTAGAATTTTATCTCAGATGCGT GGTAACCAGACCATTGATGAGGAATATGATAGCATCAAAAACAACATTGAAGAGGAGGAAAAAGAGGTTGGCTCAGGAGATCTGGAAGCC CTCAAAAAGGAAACCATTGTGTTAAAGGAAGGTTCTGAATATAGAGTCAAAATTCACTTCAAAGTGAACAGGGATATTGTGTCAGGCCTG AAATACGTTCAGCACACCTACAGGACTGGGGTGAAAGTGGATAAAGCAACATTTATGGTTGGCAGCTATGGACCTCGGCCTGAGGAGTAT GAGTTCCTCACTCCAGTTGAGGAGGCTCCCAAGGGCATGCTGGCGCGAGGCACGTACCACAACAAGTCCTTCTTCACCGACGATGACAAG CAAGACCACCTCAGCTGGGAGTGGAACCTGTCGATTAAGAAGGAGTGGACAGAATGAATGCATCCACCCCTTTCCCCACCCTTGCCACCT GGAAGAATTCTCTCAGGCGTGTTCAGCACCCTGTCCCTCCTCCCTGTCCACAGCTGGGTCCCTCTTCAACACTGCCACATTTCCTTATTG >In-frame_SLC2A13_ENST00000380858_chr12_40422103_-_ARHGDIB_ENST00000228945_chr12_15100883_-_2052nt CGCCTCCCGCCCGCTCCGCAGCGCCAGCTCGGCAGGCGCGGGGCGTGAGTGTGGAGTGAGACCCGCCGGGCTCCAACTCCGCAGCGTCGG AGCGCGGCGGGCAGCAACTTTCTCCCCGGAGCGGCCGTGGCGGCGGCTGCTGCCGTGGCAGCCGGAGCGGAAGCCGGGAGGAAGAAAGCG GCGGCAGCGGCGGTTGCTCCCGCCGGCTCGGGCTGTCTAGCTCGCCGAGACTGCCGGCCCGCGGAGCCGCGTCCCCCCGGGCAGCCCCGG GCCCCTGCCCTATGTCCCGCAAGGCAAGCGAGAATGTGGAGTACACGCTGCGGAGCCTGAGCAGCCTGATGGGCGAGCGGCGCAGGAAGC AGCCGGAGCCGGACGCGGCGAGCGCGGCCGGGGAGTGCAGCCTCCTGGCTGCCGCCGAATCGAGCACCAGCCTGCAGAGCGCGGGCGCGG GCGGCGGCGGCGTCGGGGACCTGGAGCGCGCGGCGCGGCGGCAGTTCCAGCAGGACGAGACCCCCGCCTTCGTGTACGTGGTGGCCGTCT TCTCCGCGCTGGGCGGCTTCCTGTTTGGCTATGACACCGGGGTGGTGTCAGGGGCCATGCTGCTGCTCAAGCGGCAGCTCAGTCTGGACG CGCTGTGGCAGGAGCTGCTGGTGTCCAGCACGGTGGGGGCGGCTGCCGTCTCGGCGCTGGCCGGAGGCGCCCTCAACGGCGTCTTCGGCC GCCGCGCTGCCATCCTCCTGGCCAGTGCCCTCTTCACCGCCGGCTCCGCGGTGCTGGCTGCGGCCAACAACAAGGAGACACTGCTCGCCG GCCGCCTGGTCGTGGGACTCGGCATCGGCATTGCTTCTATGACAGTGCCAGTGTACATTGCGGAGGTCTCACCACCCAATTTAAGAGGCC GATTAGTCACCATTAATACCCTCTTCATCACAGGAGGGCAGTTCTTTGCAAGTGTTGTTGATGGAGCCTTCAGTTATCTCCAGAAGGATG GATGGAGGTACATGTTGGGACTTGCAGCAGTTCCGGCGGTTATACAGTTTTTTGGCTTTCTCTTTTTGCCTGAAAGCCCTCGATGGCTTA TTCAGAAAGGACAGACTCAGAAGGCCCGTAGAATTTTATCTCAGATGCGTGGTAACCAGACCATTGATGAGGAATATGATAGCATCAAAA ACAACATTGAAGAGGAGGAAAAAGAGGTTGGCTCAGGAGATCTGGAAGCCCTCAAAAAGGAAACCATTGTGTTAAAGGAAGGTTCTGAAT ATAGAGTCAAAATTCACTTCAAAGTGAACAGGGATATTGTGTCAGGCCTGAAATACGTTCAGCACACCTACAGGACTGGGGTGAAAGTGG ATAAAGCAACATTTATGGTTGGCAGCTATGGACCTCGGCCTGAGGAGTATGAGTTCCTCACTCCAGTTGAGGAGGCTCCCAAGGGCATGC TGGCGCGAGGCACGTACCACAACAAGTCCTTCTTCACCGACGATGACAAGCAAGACCACCTCAGCTGGGAGTGGAACCTGTCGATTAAGA AGGAGTGGACAGAATGAATGCATCCACCCCTTTCCCCACCCTTGCCACCTGGAAGAATTCTCTCAGGCGTGTTCAGCACCCTGTCCCTCC TCCCTGTCCACAGCTGGGTCCCTCTTCAACACTGCCACATTTCCTTATTGATGCATCTTTTCCCACCCTGTCACTCAACGTGGTCCCTAG AACAAGAGGCTTAAAACCGGGCTTTCACCCAACCTGCTCCCTCTGATCCTCCATCAGGGCCAGATCTTCCACGTCTCCATCTCAGTACAC AATCATTTAATATTTCCCTGTCTTACCCCTATTCAAGCAACTAGAGGCCAGAAAATGGGCAAATTATCACTAACAGGTCTTTGACTCAGG TTCCAGTAGTTCATTCTAATGCCTAGATTCTTTTGTGGTTGTTGCTGGCCCAATGAGTCCCTAGTCACATCCCCTGCCAGAGGGAGTTCT >In-frame_SLC2A13_ENST00000380858_chr12_40422103_-_ARHGDIB_ENST00000541644_chr12_15100883_-_1739nt CGCCTCCCGCCCGCTCCGCAGCGCCAGCTCGGCAGGCGCGGGGCGTGAGTGTGGAGTGAGACCCGCCGGGCTCCAACTCCGCAGCGTCGG AGCGCGGCGGGCAGCAACTTTCTCCCCGGAGCGGCCGTGGCGGCGGCTGCTGCCGTGGCAGCCGGAGCGGAAGCCGGGAGGAAGAAAGCG GCGGCAGCGGCGGTTGCTCCCGCCGGCTCGGGCTGTCTAGCTCGCCGAGACTGCCGGCCCGCGGAGCCGCGTCCCCCCGGGCAGCCCCGG GCCCCTGCCCTATGTCCCGCAAGGCAAGCGAGAATGTGGAGTACACGCTGCGGAGCCTGAGCAGCCTGATGGGCGAGCGGCGCAGGAAGC AGCCGGAGCCGGACGCGGCGAGCGCGGCCGGGGAGTGCAGCCTCCTGGCTGCCGCCGAATCGAGCACCAGCCTGCAGAGCGCGGGCGCGG GCGGCGGCGGCGTCGGGGACCTGGAGCGCGCGGCGCGGCGGCAGTTCCAGCAGGACGAGACCCCCGCCTTCGTGTACGTGGTGGCCGTCT TCTCCGCGCTGGGCGGCTTCCTGTTTGGCTATGACACCGGGGTGGTGTCAGGGGCCATGCTGCTGCTCAAGCGGCAGCTCAGTCTGGACG CGCTGTGGCAGGAGCTGCTGGTGTCCAGCACGGTGGGGGCGGCTGCCGTCTCGGCGCTGGCCGGAGGCGCCCTCAACGGCGTCTTCGGCC GCCGCGCTGCCATCCTCCTGGCCAGTGCCCTCTTCACCGCCGGCTCCGCGGTGCTGGCTGCGGCCAACAACAAGGAGACACTGCTCGCCG GCCGCCTGGTCGTGGGACTCGGCATCGGCATTGCTTCTATGACAGTGCCAGTGTACATTGCGGAGGTCTCACCACCCAATTTAAGAGGCC GATTAGTCACCATTAATACCCTCTTCATCACAGGAGGGCAGTTCTTTGCAAGTGTTGTTGATGGAGCCTTCAGTTATCTCCAGAAGGATG GATGGAGGTACATGTTGGGACTTGCAGCAGTTCCGGCGGTTATACAGTTTTTTGGCTTTCTCTTTTTGCCTGAAAGCCCTCGATGGCTTA TTCAGAAAGGACAGACTCAGAAGGCCCGTAGAATTTTATCTCAGATGCGTGGTAACCAGACCATTGATGAGGAATATGATAGCATCAAAA ACAACATTGAAGAGGAGGAAAAAGAGGTTGGCTCAGGAGATCTGGAAGCCCTCAAAAAGGAAACCATTGTGTTAAAGGAAGGTTCTGAAT ATAGAGTCAAAATTCACTTCAAAGTGAACAGGGATATTGTGTCAGGCCTGAAATACGTTCAGCACACCTACAGGACTGGGGTGAAAGTGG ATAAAGCAACATTTATGGTTGGCAGCTATGGACCTCGGCCTGAGGAGTATGAGTTCCTCACTCCAGTTGAGGAGGCTCCCAAGGGCATGC TGGCGCGAGGCACGTACCACAACAAGTCCTTCTTCACCGACGATGACAAGCAAGACCACCTCAGCTGGGAGTGGAACCTGTCGATTAAGA AGGAGTGGACAGAATGAATGCATCCACCCCTTTCCCCACCCTTGCCACCTGGAAGAATTCTCTCAGGCGTGTTCAGCACCCTGTCCCTCC TCCCTGTCCACAGCTGGGTCCCTCTTCAACACTGCCACATTTCCTTATTGATGCATCTTTTCCCACCCTGTCACTCAACGTGGTCCCTAG |
Top |
FusionGenePPI for SLC2A13_ARHGDIB |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SLC2A13 | ARHGDIB | VAV1, RAC2, RHOH, RAC3, RAC1, UFM1, APP, ZBTB1, RHOA, RHOC, SUMO4, WSB1, UBE3A, U2AF2, FBXL5, CDH1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for SLC2A13_ARHGDIB |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
RelatedDiseases for SLC2A13_ARHGDIB |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | SLC2A13 | C0236969 | Substance-Related Disorders | 1 | CTD_human |
| Tgene | ARHGDIB | C0019693 | HIV Infections | 1 | CTD_human |
| Tgene | ARHGDIB | C0023893 | Liver Cirrhosis, Experimental | 1 | CTD_human |
| Tgene | ARHGDIB | C0948089 | Acute Coronary Syndrome | 1 | CTD_human |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|