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FusionGeneSummary

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FusionGeneSequence

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Fusion gene ID: 34246

FusionGeneSummary for SLC25A42_GATAD2A

check button Fusion gene summary
Fusion gene informationFusion gene name: SLC25A42_GATAD2A
Fusion gene ID: 34246
HgeneTgene
Gene symbol

SLC25A42

GATAD2A

Gene ID

284439

54815

Gene namesolute carrier family 25 member 42GATA zinc finger domain containing 2A
Synonyms-p66alpha
Cytomap

19p13.11

19p13.11

Type of geneprotein-codingprotein-coding
Descriptionmitochondrial coenzyme A transporter SLC25A42transcriptional repressor p66-alphaGATA zinc finger domain-containing protein 2A
Modification date2018052220180523
UniProtAcc

Q86VD7

Q86YP4

Ensembl transtripts involved in fusion geneENST00000318596, ENST00000600275, 
ENST00000252577, ENST00000360315, 
ENST00000537887, ENST00000404158, 
ENST00000358713, ENST00000429563, 
ENST00000473184, 
Fusion gene scores* DoF score3 X 2 X 2=128 X 7 X 7=392
# samples 39
** MAII scorelog2(3/12*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(9/392*10)=-2.12285674778553
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SLC25A42 [Title/Abstract] AND GATAD2A [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneSLC25A42

GO:0015866

ADP transport

19429682

HgeneSLC25A42

GO:0015867

ATP transport

19429682

HgeneSLC25A42

GO:0035349

coenzyme A transmembrane transport

19429682

HgeneSLC25A42

GO:0080121

AMP transport

19429682

TgeneGATAD2A

GO:0045892

negative regulation of transcription, DNA-templated

12183469


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDOVTCGA-04-1364-01ASLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000318596ENST00000252577SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
In-frameENST00000318596ENST00000360315SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
Frame-shiftENST00000318596ENST00000537887SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
Frame-shiftENST00000318596ENST00000404158SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
Frame-shiftENST00000318596ENST00000358713SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
Frame-shiftENST00000318596ENST00000429563SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
5CDS-intronENST00000318596ENST00000473184SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
3UTR-3CDSENST00000600275ENST00000252577SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
3UTR-3CDSENST00000600275ENST00000360315SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
3UTR-3CDSENST00000600275ENST00000537887SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
3UTR-3CDSENST00000600275ENST00000404158SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
3UTR-3CDSENST00000600275ENST00000358713SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
3UTR-3CDSENST00000600275ENST00000429563SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+
3UTR-intronENST00000600275ENST00000473184SLC25A42chr19

19217194

+GATAD2Achr19

19616153

+

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FusionProtFeatures for SLC25A42_GATAD2A


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SLC25A42

Q86VD7

GATAD2A

Q86YP4

Mitochondrial carrier mediating the transport ofcoenzyme A (CoA) in mitochondria in exchange forintramitochondrial (deoxy)adenine nucleotides and adenosine 3',5'-diphosphate. {ECO:0000269|PubMed:19429682}. Transcriptional repressor. Enhances MBD2-mediatedrepression. Efficient repression requires the presence of GATAD2B.{ECO:0000269|PubMed:12183469, ECO:0000269|PubMed:16415179}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC25A42chr19:19217194chr19:19616153ENST00000318596+6831_117165319RepeatNote=Solcar 1
HgeneSLC25A42chr19:19217194chr19:19616153ENST00000318596+68135_155165319TransmembraneHelical%3B Name%3D3
HgeneSLC25A42chr19:19217194chr19:19616153ENST00000318596+6833_53165319TransmembraneHelical%3B Name%3D1
HgeneSLC25A42chr19:19217194chr19:19616153ENST00000318596+6889_109165319TransmembraneHelical%3B Name%3D2

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSLC25A42chr19:19217194chr19:19616153ENST00000318596+68129_214165319RepeatNote=Solcar 2
HgeneSLC25A42chr19:19217194chr19:19616153ENST00000318596+68224_312165319RepeatNote=Solcar 3
HgeneSLC25A42chr19:19217194chr19:19616153ENST00000318596+68186_206165319TransmembraneHelical%3B Name%3D4
HgeneSLC25A42chr19:19217194chr19:19616153ENST00000318596+68230_250165319TransmembraneHelical%3B Name%3D5
HgeneSLC25A42chr19:19217194chr19:19616153ENST00000318596+68293_313165319TransmembraneHelical%3B Name%3D6
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000252577+911139_174565609Coiled coilOntology_term=ECO:0000255
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000358713+1012139_174590634Coiled coilOntology_term=ECO:0000255
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000360315+1012139_174590634Coiled coilOntology_term=ECO:0000255
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000404158+1214139_174591635Coiled coilOntology_term=ECO:0000255
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000252577+911144_178565609RegionNote=CR1%3B MBD2-binding
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000252577+911340_480565609RegionNote=CR2%3B histone tail-binding
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000358713+1012144_178590634RegionNote=CR1%3B MBD2-binding
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000358713+1012340_480590634RegionNote=CR2%3B histone tail-binding
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000360315+1012144_178590634RegionNote=CR1%3B MBD2-binding
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000360315+1012340_480590634RegionNote=CR2%3B histone tail-binding
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000404158+1214144_178591635RegionNote=CR1%3B MBD2-binding
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000404158+1214340_480591635RegionNote=CR2%3B histone tail-binding
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000252577+911411_464565609Zinc fingerGATA-type
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000358713+1012411_464590634Zinc fingerGATA-type
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000360315+1012411_464590634Zinc fingerGATA-type
TgeneGATAD2Achr19:19217194chr19:19616153ENST00000404158+1214411_464591635Zinc fingerGATA-type


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FusionGeneSequence for SLC25A42_GATAD2A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_SLC25A42_ENST00000318596_chr19_19217194_+_GATAD2A_ENST00000252577_chr19_19616153_+_209aa
MGNGVKEGPVRLHEDAEAVLSSSVSSKRDHRQVLSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLW
RGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKEMRDPCVCQPKPGGAQ

>In-frame_SLC25A42_ENST00000318596_chr19_19217194_+_GATAD2A_ENST00000360315_chr19_19616153_+_209aa
MGNGVKEGPVRLHEDAEAVLSSSVSSKRDHRQVLSSLLSGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLW
RGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKEMRDPCVCQPKPGGAQ


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_SLC25A42_ENST00000318596_chr19_19217194_+_GATAD2A_ENST00000252577_chr19_19616153_+_628nt
ATGGGTAATGGTGTGAAGGAAGGCCCGGTGCGATTGCATGAGGATGCTGAGGCTGTCCTGTCCTCGTCCGTCTCATCAAAGCGTGACCAC
AGGCAAGTGCTCAGCTCCCTGCTGTCTGGGGCCCTGGCTGGTGCCCTTGCCAAAACAGCGGTAGCTCCCCTGGACCGAACCAAAATCATC
TTCCAAGTGTCTTCAAAAAGATTTTCTGCCAAGGAGGCCTTCCGGGTCCTCTACTACACCTACCTCAACGAGGGATTTCTCAGCTTGTGG
CGCGGGAACTCGGCCACCATGGTGCGCGTGGTGCCCTACGCCGCCATCCAGTTCAGCGCACACGAGGAGTACAAGCGCATCCTGGGCAGC
TACTATGGCTTCCGTGGAGAAGCCCTGCCCCCTTGGCCTCGCCTCTTCGCCGGCGCACTGGCTGGAACGACAGCCGCTTCACTGACCTAC
CCCCTGGACCTGGTCAGAGCGCGGATGGCCGTAACCCCGAAGGAAATGCGGGACCCTTGCGTTTGTCAGCCCAAGCCTGGCGGTGCACAA

>In-frame_SLC25A42_ENST00000318596_chr19_19217194_+_GATAD2A_ENST00000360315_chr19_19616153_+_628nt
ATGGGTAATGGTGTGAAGGAAGGCCCGGTGCGATTGCATGAGGATGCTGAGGCTGTCCTGTCCTCGTCCGTCTCATCAAAGCGTGACCAC
AGGCAAGTGCTCAGCTCCCTGCTGTCTGGGGCCCTGGCTGGTGCCCTTGCCAAAACAGCGGTAGCTCCCCTGGACCGAACCAAAATCATC
TTCCAAGTGTCTTCAAAAAGATTTTCTGCCAAGGAGGCCTTCCGGGTCCTCTACTACACCTACCTCAACGAGGGATTTCTCAGCTTGTGG
CGCGGGAACTCGGCCACCATGGTGCGCGTGGTGCCCTACGCCGCCATCCAGTTCAGCGCACACGAGGAGTACAAGCGCATCCTGGGCAGC
TACTATGGCTTCCGTGGAGAAGCCCTGCCCCCTTGGCCTCGCCTCTTCGCCGGCGCACTGGCTGGAACGACAGCCGCTTCACTGACCTAC
CCCCTGGACCTGGTCAGAGCGCGGATGGCCGTAACCCCGAAGGAAATGCGGGACCCTTGCGTTTGTCAGCCCAAGCCTGGCGGTGCACAA


* Fusion transcript sequences (Full-length transcript).
>In-frame_SLC25A42_ENST00000318596_chr19_19217194_+_GATAD2A_ENST00000252577_chr19_19616153_+_4236nt
GGGGCCGTGGCGGCTGGAGGTAGCGGCGGCGGCGACGCGTCCGGGCCGGTGAGGGGGCGCGGGGGGCGCCGGGGGGGCCCAAGCGTCAGC
GGCCCGCGCCTGTCGGGCTGAACTGAGGACCGAGTCTCCTGCCATTCCGAGCAGGCCTGGTATGGGTAATGGTGTGAAGGAAGGCCCGGT
GCGATTGCATGAGGATGCTGAGGCTGTCCTGTCCTCGTCCGTCTCATCAAAGCGTGACCACAGGCAAGTGCTCAGCTCCCTGCTGTCTGG
GGCCCTGGCTGGTGCCCTTGCCAAAACAGCGGTAGCTCCCCTGGACCGAACCAAAATCATCTTCCAAGTGTCTTCAAAAAGATTTTCTGC
CAAGGAGGCCTTCCGGGTCCTCTACTACACCTACCTCAACGAGGGATTTCTCAGCTTGTGGCGCGGGAACTCGGCCACCATGGTGCGCGT
GGTGCCCTACGCCGCCATCCAGTTCAGCGCACACGAGGAGTACAAGCGCATCCTGGGCAGCTACTATGGCTTCCGTGGAGAAGCCCTGCC
CCCTTGGCCTCGCCTCTTCGCCGGCGCACTGGCTGGAACGACAGCCGCTTCACTGACCTACCCCCTGGACCTGGTCAGAGCGCGGATGGC
CGTAACCCCGAAGGAAATGCGGGACCCTTGCGTTTGTCAGCCCAAGCCTGGCGGTGCACAAGAGCTCCTCGGCCGTGGACCGCCAGCGAG
AGTACCTCCTGGACATGATCCCACCCCGCTCCATCCCCCAGTCAGCCACGTGGAAATAGTGCGAGCCAGGCCCCGTGGAAGACGGGCTCC
CTCCTCCCCCACCTGGCCCCTGGTCTAGAAGGACCCACTGCACCACCCTCCGCTGGCTCGGGAAGACACCGTGCCCGCCCCAAGAGCAAG
CACCGGCCATGCTGCAGAGGCAAGACCTCAATTCTTGGCTGCAAAGTTTCATCAGGGCTAGGGGGCTGGTGCCGCCTCATAGGCAGACGA
GGATCATCGCTGGGGGACCTTTCCCGTGGGCTTTCTTCCTTTCTCTCTTTGCCTTTAGTTTGCCCGACACCAGCAGAAAAGTGGACCTTG
GGGGCTGGTTCTGCTCCTGGCCCCCTTGTTCAGCCCCTGCCGGCACACGGGCGGCTCACCCTGGACACTGTGATGCGCATGGGCAAGGCC
AGCGCCCGGGGCTTCTGAACCGAGCGGGGTGTTTCATTTTTTTGCTTTTCCCTGTCTTAGGCTCCCAGTCTTTGACTGCCTTCCCATGGC
GATCTATAAGTTGAAAGATTTTTTTTTTTTTTAATCACCTCATGATGATGGAGTTAAAAGTAAACCGTGCAGACCCTGGGGTCCCTGTTG
TACGCTGCATCATCCCGCTGGCCCTGTGCCCTGGAGGGTGGGCGGCTCATGGTGCCACAGCCCCTGGCAGGGACGGCCGGCCCGCCCCCG
TGACTGACTGACAGATGCAGGGATGGCCGAGGCAGCCCTCGCTCCAGCTGAACGCCTCCATTGCTGCTTGTTCTGGAGACCCCCGCCCCC
GCACCTTCCAGACTTAGCAGAAGAACAAACTGAAGAACAGACCCAGCCAGAGAAGCAGGGATTCCAGAAGCTGCCCATTAAGGGAGAAGG
AGAGGATCCGGTCGGCAGCAGCCCTGAGCAGAAAGCTGGAGGGGGGACTGTCGCGGGGTTTTTCTGTTGTGGTTTATTTTATTAAATTTT
TTCCTTTTTTCTATTCATTTCGATGGACGCAATCTTAAGCCACCCTGGCCTTGCTCCTGGGAGGTGAGCGTGCACAGGTGTGTGCAGGTC
AGGAGGTGCCGTCCAGGTGTGCGGCGAGCCGCTGCGCACAGATGTCAGGATTTCCGTTTGGGTCTAGTTTAGAACCTGTCCTTAAACCTA
GGGGTTGCTGTCAGGATTTGCTTTCAGACTTTTTTTTTTTTTGTAATTCCCTTTAGAGTCTACAAAAATGTTTTTAAAAGGATCAGGTCT
GCTTTTAGTTTCATTTTTGTTTCTTTCCCGTCCCACTCTTTAAAAACTGGTTCCGTGAGGAAAGGCAGAAGCCGTTCCGTGTCTCTTGCA
GGCTGGGCCGGCTTCATGCCAGTGCGAGGGCGTCCCGTGCCCACGTACATACGTATGTCTCCATGAGTTCTGGGCTCCACTGGTTCCAAT
TGAGCTCCAGCCCTGGTTTTCCTACCCATGCAGTTAGGGACTTTAATTTAATTTTTTTTTTGTAGGGCCACCGCCTTCAAACACAACTGC
TACAACATTCTAATAAAGGCTCATTTAACCCCCAGGCTCCTGTCGTGTGAATATCCTCAGTCTGTAGGAAACTTTTTTTGACACAGCATA
GAAGACCTAGTTTTGGAAAACATTATCTAATTTTTTGTTGTGCAAATCCCCAAATTTCTCACTAATTTTTGTTTTTTTGTGCATAACTTG
GATGGGCTGAAGGAGGTGAGGACAGATTGGGGAAGGGTGGCTTTCATTCCAAGATCCAGGGATTTGGGGAAAAGGAAGGAATTTGATGTT
TTTTGGGGTGGGAGGGGAGGGTGTGTTTTTTACACCAAAAAAAAAAAAAAAAATCAAGAGTATGCAAGCATTTCTATTCCTCGCATTTTT
CTGTGTGCCTGGCAAATAAATACCTGTCTCCTACGACCCTGAGCTGTTAGCCCTCTCTGTTCCATGACAGGGGCCAGATCTTCCAGCTCC
TCCCAGAAGGAGCACCCAGGCTGGCTTCTTCCCACTGAAAGCCCTCCCCAGCGAACCAACCTCAGTTCTATGCAGTGGCTGGGGATCAGG
CATCCAGACCGAAGTCACCTCTGCCTGCTCCAGCTTGGGTCAGCTGGGTCTGACCAGGGGGCCAGATCCGAGCCGCACCTGCCGGCCCCC
AGCCCCAGCTCCAGCTCCTGACCTCTCCCAGCCTGGCCTGGCTGTTCCTCCAGGGCTGATGGCTGTCAACCCATCCTTGTGAGTTCATAT
GGACTGCTGCCCCTCGAAAGGGAGAGGGTCGGCCCCATGTCCCCAGGGAGCATTCCATCAGGGACAACGTACATACTGTGATGTAAACTT
TTTTTTTTTCCCCCCAGGGGGCAAAAGTGTGAGATGCCTTAATCTTTCCTTCATTTCTGCTGTCTCGAACACTCTAGCCCATTATTTCCT
TTCAGTTCCTTGCAGCATAACCTCTACGATAAGCCCCAAGCGGGTTGTTGTATTATGACGTTTATGATGTTCCAGGTGAAGGCATTATTA
AGTACCTCTCTGGGTGTGGGGTTTGGACGCACCAGGATAGCTATTGATTAATGTTAAGGGTGTTCTACCCACAGCAAAGCACACCCTCTT
AAACCAGGCACTGCCTGGGTCCTGGTCCCGAGAGCCCTACCAGGATCAGGTTCCTGCAAGCCGTCAGAATGTGGGAGCCCCCAGCCCAAC
TGATTGTAACTGTCCCCTGTTACCTGTGACATGAACCTCCAACAGCACCTGGAAACGGTTCCCTCTGTCAGCTGCTCTGTAGACAGGGCT
GGGGAGATCTCAGAGTTCACACCTCGCCTGTTGTAGGGGAGGTTGGGGGTAGGGTTTGGAATGGCCAAGTGCCCTTGGAACCTCCCACAG
CTATGGCCGTCCTGACCTCATCCCAGGAACTCTACGGTGACCAGGAACCACCCCTCTGACGAGGTCTGTAGCGGCCCTTCTCAGAGTGGA
ACAGCCCACAGTGCTAGTTGTGCCTGGTCTTACCTGTACTCCACGGACCTCGGTGAAGCAAAAGCTTCAGGGCAGAGGGAATGAGGCAAC
CCAGTGGCAGCCCCGCTGGGCCCCGTGGCTCCTGCTCTCCTATTGGACGTAGAGGCAGGGGAGAGACTTCTCTATACAAATATTCTCATC
ACAGAAGGGATGATCCTTGCTGCTCTGCCGTAGGGTTTTTGATGCTGAGCTATGCTGCACATGACGTTAACCTAAAGAACTTGGACTGAG
CTTTTAAAAAAGGACAGCAAACAATTTTATAATCCTTAAAGTGTAATAGACGGTTACACTAGTGCAGGGTATTGGGGAGGCTCTTTGGGT
GTGGAGGCTGTCACTTGTATTTATTGTGACTCTAAATCTTTGATAGTAAAACAAATGTAAAAAGAAATGTTTGCCACCAGATGGGAATAG
AAGTTCCAATAAGCAGGCTGGAATGGGTGGCTATACGTTGTATCACGAGGAAGTTTTAGACTCTGAAGGATAATAAATGGATGATGTGTC

>In-frame_SLC25A42_ENST00000318596_chr19_19217194_+_GATAD2A_ENST00000360315_chr19_19616153_+_4236nt
GGGGCCGTGGCGGCTGGAGGTAGCGGCGGCGGCGACGCGTCCGGGCCGGTGAGGGGGCGCGGGGGGCGCCGGGGGGGCCCAAGCGTCAGC
GGCCCGCGCCTGTCGGGCTGAACTGAGGACCGAGTCTCCTGCCATTCCGAGCAGGCCTGGTATGGGTAATGGTGTGAAGGAAGGCCCGGT
GCGATTGCATGAGGATGCTGAGGCTGTCCTGTCCTCGTCCGTCTCATCAAAGCGTGACCACAGGCAAGTGCTCAGCTCCCTGCTGTCTGG
GGCCCTGGCTGGTGCCCTTGCCAAAACAGCGGTAGCTCCCCTGGACCGAACCAAAATCATCTTCCAAGTGTCTTCAAAAAGATTTTCTGC
CAAGGAGGCCTTCCGGGTCCTCTACTACACCTACCTCAACGAGGGATTTCTCAGCTTGTGGCGCGGGAACTCGGCCACCATGGTGCGCGT
GGTGCCCTACGCCGCCATCCAGTTCAGCGCACACGAGGAGTACAAGCGCATCCTGGGCAGCTACTATGGCTTCCGTGGAGAAGCCCTGCC
CCCTTGGCCTCGCCTCTTCGCCGGCGCACTGGCTGGAACGACAGCCGCTTCACTGACCTACCCCCTGGACCTGGTCAGAGCGCGGATGGC
CGTAACCCCGAAGGAAATGCGGGACCCTTGCGTTTGTCAGCCCAAGCCTGGCGGTGCACAAGAGCTCCTCGGCCGTGGACCGCCAGCGAG
AGTACCTCCTGGACATGATCCCACCCCGCTCCATCCCCCAGTCAGCCACGTGGAAATAGTGCGAGCCAGGCCCCGTGGAAGACGGGCTCC
CTCCTCCCCCACCTGGCCCCTGGTCTAGAAGGACCCACTGCACCACCCTCCGCTGGCTCGGGAAGACACCGTGCCCGCCCCAAGAGCAAG
CACCGGCCATGCTGCAGAGGCAAGACCTCAATTCTTGGCTGCAAAGTTTCATCAGGGCTAGGGGGCTGGTGCCGCCTCATAGGCAGACGA
GGATCATCGCTGGGGGACCTTTCCCGTGGGCTTTCTTCCTTTCTCTCTTTGCCTTTAGTTTGCCCGACACCAGCAGAAAAGTGGACCTTG
GGGGCTGGTTCTGCTCCTGGCCCCCTTGTTCAGCCCCTGCCGGCACACGGGCGGCTCACCCTGGACACTGTGATGCGCATGGGCAAGGCC
AGCGCCCGGGGCTTCTGAACCGAGCGGGGTGTTTCATTTTTTTGCTTTTCCCTGTCTTAGGCTCCCAGTCTTTGACTGCCTTCCCATGGC
GATCTATAAGTTGAAAGATTTTTTTTTTTTTTAATCACCTCATGATGATGGAGTTAAAAGTAAACCGTGCAGACCCTGGGGTCCCTGTTG
TACGCTGCATCATCCCGCTGGCCCTGTGCCCTGGAGGGTGGGCGGCTCATGGTGCCACAGCCCCTGGCAGGGACGGCCGGCCCGCCCCCG
TGACTGACTGACAGATGCAGGGATGGCCGAGGCAGCCCTCGCTCCAGCTGAACGCCTCCATTGCTGCTTGTTCTGGAGACCCCCGCCCCC
GCACCTTCCAGACTTAGCAGAAGAACAAACTGAAGAACAGACCCAGCCAGAGAAGCAGGGATTCCAGAAGCTGCCCATTAAGGGAGAAGG
AGAGGATCCGGTCGGCAGCAGCCCTGAGCAGAAAGCTGGAGGGGGGACTGTCGCGGGGTTTTTCTGTTGTGGTTTATTTTATTAAATTTT
TTCCTTTTTTCTATTCATTTCGATGGACGCAATCTTAAGCCACCCTGGCCTTGCTCCTGGGAGGTGAGCGTGCACAGGTGTGTGCAGGTC
AGGAGGTGCCGTCCAGGTGTGCGGCGAGCCGCTGCGCACAGATGTCAGGATTTCCGTTTGGGTCTAGTTTAGAACCTGTCCTTAAACCTA
GGGGTTGCTGTCAGGATTTGCTTTCAGACTTTTTTTTTTTTTGTAATTCCCTTTAGAGTCTACAAAAATGTTTTTAAAAGGATCAGGTCT
GCTTTTAGTTTCATTTTTGTTTCTTTCCCGTCCCACTCTTTAAAAACTGGTTCCGTGAGGAAAGGCAGAAGCCGTTCCGTGTCTCTTGCA
GGCTGGGCCGGCTTCATGCCAGTGCGAGGGCGTCCCGTGCCCACGTACATACGTATGTCTCCATGAGTTCTGGGCTCCACTGGTTCCAAT
TGAGCTCCAGCCCTGGTTTTCCTACCCATGCAGTTAGGGACTTTAATTTAATTTTTTTTTTGTAGGGCCACCGCCTTCAAACACAACTGC
TACAACATTCTAATAAAGGCTCATTTAACCCCCAGGCTCCTGTCGTGTGAATATCCTCAGTCTGTAGGAAACTTTTTTTGACACAGCATA
GAAGACCTAGTTTTGGAAAACATTATCTAATTTTTTGTTGTGCAAATCCCCAAATTTCTCACTAATTTTTGTTTTTTTGTGCATAACTTG
GATGGGCTGAAGGAGGTGAGGACAGATTGGGGAAGGGTGGCTTTCATTCCAAGATCCAGGGATTTGGGGAAAAGGAAGGAATTTGATGTT
TTTTGGGGTGGGAGGGGAGGGTGTGTTTTTTACACCAAAAAAAAAAAAAAAAATCAAGAGTATGCAAGCATTTCTATTCCTCGCATTTTT
CTGTGTGCCTGGCAAATAAATACCTGTCTCCTACGACCCTGAGCTGTTAGCCCTCTCTGTTCCATGACAGGGGCCAGATCTTCCAGCTCC
TCCCAGAAGGAGCACCCAGGCTGGCTTCTTCCCACTGAAAGCCCTCCCCAGCGAACCAACCTCAGTTCTATGCAGTGGCTGGGGATCAGG
CATCCAGACCGAAGTCACCTCTGCCTGCTCCAGCTTGGGTCAGCTGGGTCTGACCAGGGGGCCAGATCCGAGCCGCACCTGCCGGCCCCC
AGCCCCAGCTCCAGCTCCTGACCTCTCCCAGCCTGGCCTGGCTGTTCCTCCAGGGCTGATGGCTGTCAACCCATCCTTGTGAGTTCATAT
GGACTGCTGCCCCTCGAAAGGGAGAGGGTCGGCCCCATGTCCCCAGGGAGCATTCCATCAGGGACAACGTACATACTGTGATGTAAACTT
TTTTTTTTTCCCCCCAGGGGGCAAAAGTGTGAGATGCCTTAATCTTTCCTTCATTTCTGCTGTCTCGAACACTCTAGCCCATTATTTCCT
TTCAGTTCCTTGCAGCATAACCTCTACGATAAGCCCCAAGCGGGTTGTTGTATTATGACGTTTATGATGTTCCAGGTGAAGGCATTATTA
AGTACCTCTCTGGGTGTGGGGTTTGGACGCACCAGGATAGCTATTGATTAATGTTAAGGGTGTTCTACCCACAGCAAAGCACACCCTCTT
AAACCAGGCACTGCCTGGGTCCTGGTCCCGAGAGCCCTACCAGGATCAGGTTCCTGCAAGCCGTCAGAATGTGGGAGCCCCCAGCCCAAC
TGATTGTAACTGTCCCCTGTTACCTGTGACATGAACCTCCAACAGCACCTGGAAACGGTTCCCTCTGTCAGCTGCTCTGTAGACAGGGCT
GGGGAGATCTCAGAGTTCACACCTCGCCTGTTGTAGGGGAGGTTGGGGGTAGGGTTTGGAATGGCCAAGTGCCCTTGGAACCTCCCACAG
CTATGGCCGTCCTGACCTCATCCCAGGAACTCTACGGTGACCAGGAACCACCCCTCTGACGAGGTCTGTAGCGGCCCTTCTCAGAGTGGA
ACAGCCCACAGTGCTAGTTGTGCCTGGTCTTACCTGTACTCCACGGACCTCGGTGAAGCAAAAGCTTCAGGGCAGAGGGAATGAGGCAAC
CCAGTGGCAGCCCCGCTGGGCCCCGTGGCTCCTGCTCTCCTATTGGACGTAGAGGCAGGGGAGAGACTTCTCTATACAAATATTCTCATC
ACAGAAGGGATGATCCTTGCTGCTCTGCCGTAGGGTTTTTGATGCTGAGCTATGCTGCACATGACGTTAACCTAAAGAACTTGGACTGAG
CTTTTAAAAAAGGACAGCAAACAATTTTATAATCCTTAAAGTGTAATAGACGGTTACACTAGTGCAGGGTATTGGGGAGGCTCTTTGGGT
GTGGAGGCTGTCACTTGTATTTATTGTGACTCTAAATCTTTGATAGTAAAACAAATGTAAAAAGAAATGTTTGCCACCAGATGGGAATAG
AAGTTCCAATAAGCAGGCTGGAATGGGTGGCTATACGTTGTATCACGAGGAAGTTTTAGACTCTGAAGGATAATAAATGGATGATGTGTC


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FusionGenePPI for SLC25A42_GATAD2A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
SLC25A42HDAC11GATAD2AMBD2, MBD3, HDAC1, RBBP4, RBBP7, HIST2H2AC, HIST2H2BE, HIST1H3A, HIST1H4A, CHD4, SOX2, CHD7, ELAVL1, MTA2, HDAC2, CHD3, MTA3, KRT40, OBSL1, PSME3, ZNF219, PHF20L1, FAM219A, MBD3L1, ZBTB46, CHD5, GATAD2B, MTA1, RUVBL1, KRAS, HIST1H3E, KPNA1, TCF20, CDK2AP1, HMG20A, ZMYND8, ZNF687, NABP2, RBPJ, NFATC2, ZNF592, APPBP2, CPNE5, IKZF1, DLD, TRIM25, ZNF827


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for SLC25A42_GATAD2A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SLC25A42_GATAD2A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource