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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 33823

FusionGeneSummary for SHROOM3_SCARB2

check button Fusion gene summary
Fusion gene informationFusion gene name: SHROOM3_SCARB2
Fusion gene ID: 33823
HgeneTgene
Gene symbol

SHROOM3

SCARB2

Gene ID

57619

950

Gene nameshroom family member 3scavenger receptor class B member 2
SynonymsAPXL3|MSTP013|SHRM|ShrmLAMRF|CD36L2|EPM4|HLGP85|LGP85|LIMP-2|LIMPII|SR-BII
Cytomap

4q21.1

4q21.1

Type of geneprotein-codingprotein-coding
Descriptionprotein Shroom3F-actin-binding proteinshroom-related proteinlysosome membrane protein 285 kDa lysosomal membrane sialoglycoprotein85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II
Modification date2018052320180519
UniProtAcc

Q8TF72

Q14108

Ensembl transtripts involved in fusion geneENST00000296043, ENST00000473602, 
ENST00000264896, ENST00000452464, 
Fusion gene scores* DoF score15 X 11 X 9=14855 X 4 X 3=60
# samples 175
** MAII scorelog2(17/1485*10)=-3.12685627955043
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(5/60*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: SHROOM3 [Title/Abstract] AND SCARB2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDLUADTCGA-91-6847-01ASHROOM3chr4

77692051

+SCARB2chr4

77117017

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000296043ENST00000264896SHROOM3chr4

77692051

+SCARB2chr4

77117017

-
In-frameENST00000296043ENST00000452464SHROOM3chr4

77692051

+SCARB2chr4

77117017

-
intron-3CDSENST00000473602ENST00000264896SHROOM3chr4

77692051

+SCARB2chr4

77117017

-
intron-3CDSENST00000473602ENST00000452464SHROOM3chr4

77692051

+SCARB2chr4

77117017

-

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FusionProtFeatures for SHROOM3_SCARB2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
SHROOM3

Q8TF72

SCARB2

Q14108

Controls cell shape changes in the neuroepitheliumduring neural tube closure. Induces apical constriction inepithelial cells by promoting the apical accumulation of F-actinand myosin II, and probably by bundling stress fibers. Inducesapicobasal cell elongation by redistributing gamma-tubulin anddirecting the assembly of robust apicobasal microtubule arrays (Bysimilarity). {ECO:0000250}. Acts as a lysosomal receptor for glucosylceramidase(GBA) targeting. {ECO:0000269|PubMed:18022370}. (Microbial infection) Acts as a receptor for enterovirus71. {ECO:0000269|PubMed:19543282}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSHROOM3chr4:77692051chr4:77117017ENST00000296043+101125_11018741997DomainPDZ
HgeneSHROOM3chr4:77692051chr4:77117017ENST00000296043+1011928_103018741997DomainASD1
TgeneSCARB2chr4:77692051chr4:77117017ENST00000264896-012460_47839479Topological domainCytoplasmic
TgeneSCARB2chr4:77692051chr4:77117017ENST00000452464-09460_47839336Topological domainCytoplasmic
TgeneSCARB2chr4:77692051chr4:77117017ENST00000264896-012434_45939479TransmembraneHelical
TgeneSCARB2chr4:77692051chr4:77117017ENST00000452464-09434_45939336TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneSHROOM3chr4:77692051chr4:77117017ENST00000296043+10111669_195718741997DomainASD2
TgeneSCARB2chr4:77692051chr4:77117017ENST00000264896-0121_439479Topological domainCytoplasmic
TgeneSCARB2chr4:77692051chr4:77117017ENST00000264896-01228_43339479Topological domainLumenal
TgeneSCARB2chr4:77692051chr4:77117017ENST00000452464-091_439336Topological domainCytoplasmic
TgeneSCARB2chr4:77692051chr4:77117017ENST00000452464-0928_43339336Topological domainLumenal
TgeneSCARB2chr4:77692051chr4:77117017ENST00000264896-0125_2739479TransmembraneHelical
TgeneSCARB2chr4:77692051chr4:77117017ENST00000452464-095_2739336TransmembraneHelical


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FusionGeneSequence for SHROOM3_SCARB2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_SHROOM3_ENST00000296043_chr4_77692051_+_SCARB2_ENST00000264896_chr4_77117017_-_2314aa
MMRTTEDFHKPSATLNSNTATKGRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHINEVTLSSSRKE
AVSLVKGSYKTLRLVVRRDVCTDPGHADTGASNFVSPEHLTSGPQHRKAAWSGGVKLRLKHRRSEPAGRPHSWHTTKSGEKQPDASMMQI
SQGMIGPPWHQSYHSSSSTSDLSNYDHAYLRRSPDQCSSQGSMESLEPSGAYPPCHLSPAKSTGSIDQLSHFHNKRDSAYSSFSTSSSIL
EYPHPGISGRERSGSMDNTSARGGLLEGMRQADIRYVKTVYDTRRGVSAEYEVNSSALLLQGREARASANGQGYDKWSNIPRGKGVPPPS
WSQQCPSSLETATDNLPPKVGAPLPPARSDSYAAFRHRERPSSWSSLDQKRLCRPQANSLGSLKSPFIEEQLHTVLEKSPENSPPVKPKH
NYTQKAQPGQPLLPTSIYPVPSLEPHFAQVPQPSVSSNGMLYPALAKESGYIAPQGACNKMATIDENGNQNGSGRPGFAFCQPLEHDLLS
PVEKKPEATAKYVPSKVHFCSVPENEEDASLKRHLTPPQGNSPHSNERKSTHSNKPSSHPHSLKCPQAQAWQAGEDKRSSRLSEPWEGDF
QEDHNANLWRRLEREGLGQSLSGNFGKTKSAFSSLQNIPESLRRHSSLELGRGTQEGYPGGRPTCAVNTKAEDPGRKAAPDLGSHLDRQV
SYPRPEGRTGASASFNSTDPSPEEPPAPSHPHTSSLGRRGPGPGSASALQGFQYGKPHCSVLEKVSKFEQREQGSQRPSVGGSGFGHNYR
PHRTVSTSSTSGNDFEETKAHIRFSESAEPLGNGEQHFKNGELKLEEASRQPCGQQLSGGASDSGRGPQRPDARLLRSQSTFQLSSEPER
EPEWRDRPGSPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRDLELGAPVASRSWRPRPSSAHVGLRSPEASASASPHTPRERHSVTP
AEGDLARPVPPAARRGARRRLTPEQKKRSYSEPEKMNEVGIVEEAEPAPLGPQRNGMRFPESSVADRRRLFERDGKACSTLSLSGPELKQ
FQQSALADYIQRKTGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREATLLPATVAETQQAPRDR
SSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWGARAGKSMSAEDLLERSDVLAGPVHVRSRSSPATADKRQDVLLGQDSG
FGLVKDPCYLAGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAP
LTPIGTPLPSAIPSGYCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAARED
SLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPP
PPPPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPSFMSV
HAQLAGSLGGQPAPIQTQSLSHDPVSGTQGLEKKVSPDPQKSSEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLL
KENSVKRKAIQRTVSSSGCEGKRNEDKEAVSMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVNEKKAELIGSLTHKLETLQEA
KGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGDLDKVVNLLLSLSGRLARVENVLSGLGEDASNEERKIVLRNGTEAFDSWEK
PPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTLNIPVLTVIE
WSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHVFRPDISPYFGLFYEKNGTNDGDYVFLTGEDSYLNFTKIVEWNGKT
SLDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLN
VSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESV

>In-frame_SHROOM3_ENST00000296043_chr4_77692051_+_SCARB2_ENST00000452464_chr4_77117017_-_2171aa
MMRTTEDFHKPSATLNSNTATKGRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHINEVTLSSSRKE
AVSLVKGSYKTLRLVVRRDVCTDPGHADTGASNFVSPEHLTSGPQHRKAAWSGGVKLRLKHRRSEPAGRPHSWHTTKSGEKQPDASMMQI
SQGMIGPPWHQSYHSSSSTSDLSNYDHAYLRRSPDQCSSQGSMESLEPSGAYPPCHLSPAKSTGSIDQLSHFHNKRDSAYSSFSTSSSIL
EYPHPGISGRERSGSMDNTSARGGLLEGMRQADIRYVKTVYDTRRGVSAEYEVNSSALLLQGREARASANGQGYDKWSNIPRGKGVPPPS
WSQQCPSSLETATDNLPPKVGAPLPPARSDSYAAFRHRERPSSWSSLDQKRLCRPQANSLGSLKSPFIEEQLHTVLEKSPENSPPVKPKH
NYTQKAQPGQPLLPTSIYPVPSLEPHFAQVPQPSVSSNGMLYPALAKESGYIAPQGACNKMATIDENGNQNGSGRPGFAFCQPLEHDLLS
PVEKKPEATAKYVPSKVHFCSVPENEEDASLKRHLTPPQGNSPHSNERKSTHSNKPSSHPHSLKCPQAQAWQAGEDKRSSRLSEPWEGDF
QEDHNANLWRRLEREGLGQSLSGNFGKTKSAFSSLQNIPESLRRHSSLELGRGTQEGYPGGRPTCAVNTKAEDPGRKAAPDLGSHLDRQV
SYPRPEGRTGASASFNSTDPSPEEPPAPSHPHTSSLGRRGPGPGSASALQGFQYGKPHCSVLEKVSKFEQREQGSQRPSVGGSGFGHNYR
PHRTVSTSSTSGNDFEETKAHIRFSESAEPLGNGEQHFKNGELKLEEASRQPCGQQLSGGASDSGRGPQRPDARLLRSQSTFQLSSEPER
EPEWRDRPGSPESPLLDAPFSRAYRNSIKDAQSRVLGATSFRRRDLELGAPVASRSWRPRPSSAHVGLRSPEASASASPHTPRERHSVTP
AEGDLARPVPPAARRGARRRLTPEQKKRSYSEPEKMNEVGIVEEAEPAPLGPQRNGMRFPESSVADRRRLFERDGKACSTLSLSGPELKQ
FQQSALADYIQRKTGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREATLLPATVAETQQAPRDR
SSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWGARAGKSMSAEDLLERSDVLAGPVHVRSRSSPATADKRQDVLLGQDSG
FGLVKDPCYLAGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQASRTPCPRPPLAGTQGLVTDTRAAP
LTPIGTPLPSAIPSGYCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEHGVEEGTRKRVSLPQWPPPSRAKWAHAARED
SLPEESSAPDFANLKHYQKQQSLPSLCSTSDPDTPLGAPSTPGRISLRISESVLRDSPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPP
PPPPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPSFMSV
HAQLAGSLGGQPAPIQTQSLSHDPVSGTQGLEKKVSPDPQKSSEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLL
KENSVKRKAIQRTVSSSGCEGKRNEDKEAVSMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVNEKKAELIGSLTHKLETLQEA
KGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGDLDKVVNLLLSLSGRLARVENVLSGLGEDASNEERKIVLRNGTEAFDSWEK
PPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRSLDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQ
GLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILK
AAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTLIITNIPYIIMALGVFFGLVFTWLACKGQGSMDEGT


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_SHROOM3_ENST00000296043_chr4_77692051_+_SCARB2_ENST00000264896_chr4_77117017_-_6942nt
ATGATGAGGACCACTGAAGACTTCCACAAGCCTAGTGCCACATTAAACTCTAACACGGCCACCAAGGGAAGGTACATTTATCTGGAGGCA
TTCCTGGAGGGAGGAGCTCCCTGGGGTTTTACTCTAAAGGGTGGCCTGGAGCACGGAGAACCATTAATCATCTCTAAGGTCGAAGAAGGG
GGCAAAGCAGACACCCTGAGCTCCAAACTGCAGGCTGGGGATGAGGTTGTGCACATCAATGAGGTGACTCTGAGCAGCTCCAGAAAGGAG
GCAGTTTCCCTGGTGAAAGGATCCTACAAGACCCTCAGGCTGGTAGTGCGCAGAGATGTGTGCACAGACCCAGGCCATGCAGATACTGGT
GCCTCTAACTTCGTCAGCCCAGAACACCTCACCTCTGGCCCCCAGCACAGGAAAGCAGCGTGGTCAGGAGGGGTTAAACTTCGGCTGAAG
CACAGGCGCAGTGAGCCTGCAGGCCGACCTCACTCGTGGCACACAACTAAATCTGGGGAGAAGCAACCCGATGCCAGCATGATGCAGATA
TCTCAGGGTATGATCGGCCCTCCTTGGCACCAAAGCTACCATTCCAGCTCCTCTACTAGTGACCTCTCCAACTATGACCATGCTTATCTA
AGGCGGAGCCCTGACCAGTGCAGCTCCCAGGGGAGCATGGAGAGCCTGGAGCCCAGTGGGGCATACCCACCCTGTCATCTTTCCCCTGCC
AAGTCCACCGGCAGCATTGACCAGCTCAGCCACTTCCATAACAAGAGAGACTCGGCTTACAGCTCTTTCTCCACCAGTTCTAGCATCCTA
GAGTATCCACACCCTGGCATCTCTGGCCGGGAGCGTTCAGGCTCCATGGACAATACTTCTGCTCGAGGTGGCCTCCTCGAAGGGATGAGG
CAGGCAGATATTCGCTATGTCAAGACAGTCTATGACACCCGGAGGGGAGTCTCAGCAGAGTATGAGGTGAACTCTTCAGCCCTGCTGCTT
CAAGGTAGGGAGGCCCGAGCCTCAGCAAATGGTCAGGGCTATGATAAATGGTCTAATATTCCTCGGGGCAAGGGAGTGCCACCCCCATCC
TGGAGCCAGCAGTGCCCCAGTTCCTTGGAGACTGCCACGGACAACCTTCCTCCTAAGGTGGGTGCACCCCTGCCTCCAGCTCGGAGTGAC
AGTTACGCAGCATTTCGGCACCGTGAGCGGCCCAGCTCCTGGTCTAGCCTTGATCAGAAACGGCTCTGCCGGCCTCAGGCAAACTCTTTA
GGCTCCCTGAAGTCTCCATTCATAGAGGAGCAGCTGCATACTGTGCTGGAGAAGAGTCCAGAGAACAGCCCCCCAGTGAAGCCCAAGCAT
AACTATACCCAGAAGGCCCAACCTGGCCAACCTCTGCTGCCGACCAGCATCTACCCGGTACCTTCCCTGGAGCCACACTTTGCCCAGGTG
CCTCAGCCTTCTGTGAGTAGCAACGGTATGCTCTACCCTGCACTGGCCAAGGAGAGTGGATACATAGCCCCTCAGGGAGCATGCAACAAG
ATGGCTACCATTGATGAGAATGGGAACCAGAATGGATCTGGCAGGCCTGGGTTTGCCTTCTGCCAGCCCTTAGAACATGACTTGCTGTCC
CCAGTGGAGAAGAAACCAGAAGCTACAGCCAAGTATGTCCCCTCCAAAGTCCATTTCTGTTCAGTGCCTGAAAATGAGGAGGATGCCTCC
CTGAAGAGACATCTCACACCTCCCCAAGGCAACAGCCCACATTCCAATGAGAGAAAGAGCACCCACAGTAACAAACCATCTTCTCATCCC
CACAGCCTCAAATGCCCTCAGGCTCAGGCCTGGCAAGCGGGTGAAGACAAGAGATCTTCCAGGCTCTCAGAGCCCTGGGAGGGCGATTTC
CAGGAAGACCACAATGCCAACCTCTGGAGGAGGCTGGAGAGAGAAGGCCTAGGCCAGAGCCTGTCAGGCAACTTTGGCAAGACCAAGTCA
GCCTTCTCATCTCTCCAGAACATTCCTGAGAGTCTGAGAAGACACAGCAGCCTGGAGCTAGGCCGGGGAACCCAGGAGGGTTACCCCGGG
GGCAGGCCCACCTGTGCAGTCAACACCAAGGCAGAAGACCCTGGGAGGAAAGCCGCTCCTGACCTCGGGAGCCATCTGGACCGGCAGGTT
TCCTACCCGCGGCCCGAGGGGAGGACCGGTGCCTCGGCTTCTTTCAACAGCACAGACCCAAGTCCCGAAGAGCCGCCTGCCCCCTCGCAC
CCGCACACATCCAGTCTGGGCCGGAGGGGGCCCGGCCCAGGCAGCGCCTCGGCTCTTCAGGGCTTTCAGTACGGGAAGCCCCACTGCTCG
GTGCTGGAGAAGGTCTCCAAATTCGAGCAGCGAGAGCAAGGGAGCCAGAGACCGAGTGTGGGCGGCTCTGGTTTTGGCCATAACTATAGG
CCCCACAGGACCGTCTCAACTTCCAGTACTTCTGGGAATGACTTCGAGGAGACAAAAGCACACATTCGTTTCTCTGAGTCAGCTGAACCC
CTAGGCAACGGGGAGCAGCACTTCAAAAACGGGGAGCTGAAGTTGGAAGAGGCTTCCCGGCAGCCCTGCGGTCAGCAGCTGAGCGGAGGA
GCGTCGGACAGCGGCCGTGGCCCCCAGAGGCCGGACGCTCGGCTCCTCCGTAGCCAGAGCACCTTCCAGCTCTCCAGCGAGCCAGAGAGG
GAGCCCGAGTGGCGGGACAGGCCCGGCTCGCCCGAATCGCCCCTGCTGGATGCCCCCTTCAGCCGCGCCTACCGGAACAGCATCAAGGAC
GCACAGTCCCGTGTCTTGGGGGCCACCTCCTTTCGACGTCGAGACCTGGAGCTGGGGGCGCCCGTGGCGTCGAGGTCCTGGCGGCCACGG
CCTTCCTCGGCCCACGTGGGGCTGCGGAGCCCCGAGGCGTCGGCCTCCGCCTCCCCGCACACGCCCCGGGAGCGGCACAGCGTGACCCCT
GCTGAGGGCGACCTGGCCAGGCCCGTGCCCCCTGCCGCCCGGAGAGGTGCTCGCCGGCGCCTGACTCCCGAGCAGAAGAAGCGCTCCTAC
TCGGAGCCCGAGAAGATGAACGAGGTGGGGATCGTGGAGGAGGCCGAACCGGCACCCCTGGGCCCGCAGAGAAATGGGATGCGTTTCCCG
GAGAGCAGCGTGGCCGACCGGCGCCGTCTCTTCGAGCGCGATGGCAAGGCCTGCTCCACGCTCAGCCTGTCGGGGCCCGAGCTGAAGCAG
TTCCAGCAGAGCGCCCTGGCGGACTACATCCAGCGCAAGACCGGCAAGCGGCCTACCTCCGCCGCCGGCTGCAGCCTCCAGGAGCCCGGG
CCACTGCGTGAGCGCGCCCAGAGTGCCTACCTCCAGCCCGGCCCCGCGGCGCTCGAAGGCTCCGGCCTCGCCTCGGCCTCCAGCTTGAGC
TCACTGCGGGAGCCCAGCCTGCAGCCCCGCAGGGAGGCCACGCTCCTGCCGGCCACAGTTGCAGAAACCCAGCAGGCTCCCCGAGATCGC
AGCAGCTCCTTCGCCGGTGGCCGCCGCCTCGGGGAACGGCGACGCGGGGACCTGCTTAGCGGAGCAAACGGTGGAACAAGGGGCACCCAG
AGAGGGGATGAGACCCCCAGGGAGCCATCCTCCTGGGGGGCCAGGGCCGGGAAGTCCATGTCGGCCGAGGACCTGCTGGAACGCTCGGAC
GTCCTTGCGGGCCCTGTCCATGTGAGGTCCAGGTCATCTCCCGCCACCGCAGACAAGCGCCAGGATGTGCTTTTGGGGCAAGACAGTGGC
TTTGGTCTTGTGAAGGATCCATGTTATTTGGCTGGTCCTGGATCTAGGTCACTCAGTTGTTCAGAAAGAGGCCAAGAAGAGATGCTGCCG
CTCTTCCACCATCTCACCCCTCGTTGGGGTGGTTCAGGCTGCAAAGCCATTGGTGATTCCTCCGTTCCTAGTGAATGTCCTGGAACCCTG
GACCATCAGAGGCAAGCCAGTAGGACACCCTGCCCCAGGCCACCACTGGCAGGAACGCAAGGGCTGGTCACAGACACCAGGGCTGCACCC
CTGACCCCAATTGGCACCCCTCTGCCTTCAGCCATTCCCTCTGGCTACTGCTCACAGGACGGTCAGACAGGGCGACAGCCTCTCCCGCCC
TACACCCCTGCCATGATGCACAGAAGCAATGGTCACACCCTGACCCAGCCTCCCGGTCCAAGAGGCTGTGAGGGCGATGGCCCAGAGCAT
GGGGTAGAAGAGGGAACGAGGAAGAGGGTCTCGCTGCCTCAGTGGCCACCTCCTTCTCGAGCAAAGTGGGCCCACGCAGCCAGAGAGGAC
AGCCTTCCTGAGGAATCCTCAGCCCCTGATTTTGCAAACCTGAAGCACTATCAAAAACAGCAGAGTCTTCCAAGTTTATGCAGCACTTCT
GACCCAGACACACCTCTTGGGGCCCCGAGCACTCCAGGGAGGATCTCCCTCCGAATATCTGAGTCTGTCCTGCGGGACTCCCCGCCACCT
CATGAGGATTATGAAGACGAAGTGTTTGTGAGGGATCCGCACCCCAAGGCCACGTCCAGCCCCACATTTGAACCTCTTCCCCCACCCCCA
CCTCCTCCACCGAGTCAGGAAACCCCGGTGTATAGCATGGATGACTTCCCTCCACCTCCTCCCCACACTGTATGTGAGGCGCAGCTGGAC
AGTGAGGATCCCGAGGGGCCACGCCCCAGCTTCAACAAACTTTCTAAAGTGACAATTGCAAGGGAAAGGCACATGCCTGGTGCAGCCCAT
GTGGTAGGTAGTCAGACACTGGCTTCCAGACTCCAAACTTCTATCAAGGGTTCAGAGGCTGAGTCCACACCACCCTCCTTCATGAGCGTT
CACGCCCAACTTGCTGGGTCTCTTGGTGGGCAGCCAGCACCCATCCAGACTCAAAGCCTCAGCCATGATCCAGTCAGTGGAACTCAGGGT
TTAGAAAAGAAAGTCAGTCCTGATCCTCAGAAGAGTTCAGAAGACATCAGAACAGAGGCTTTGGCCAAGGAAATTGTCCACCAAGACAAA
TCTCTAGCAGACATTTTGGATCCAGACTCCAGGCTGAAGACAACAATGGACCTGATGGAAGGTTTGTTTCCCCGAGATGTGAACTTGCTG
AAGGAAAACAGTGTAAAGAGGAAGGCCATACAGAGAACTGTCAGCTCTTCAGGATGTGAAGGCAAGAGGAATGAAGACAAGGAAGCAGTG
AGCATGTTGGTTAACTGCCCTGCCTACTACAGTGTGTCTGCTCCCAAGGCTGAGCTACTGAACAAAATCAAAGAGATGCCAGCAGAAGTG
AATGAGGAAGAGGAACAGGCAGATGTCAATGAAAAGAAGGCTGAGCTCATTGGAAGTCTCACCCACAAGCTGGAGACCCTCCAGGAGGCG
AAGGGGAGCCTGCTCACGGACATCAAGCTCAACAACGCCCTGGGAGAAGAGGTGGAGGCTCTGATCAGCGAGCTCTGCAAGCCCAATGAG
TTTGACAAGTATAGGATGTTCATAGGGGATTTGGACAAGGTGGTCAACCTGCTGCTCTCCCTCTCGGGGCGTCTAGCCCGTGTTGAGAAT
GTCCTTAGCGGCCTTGGTGAAGATGCCAGTAATGAAGAAAGGAAAATTGTGTTAAGGAATGGTACTGAGGCATTTGACTCCTGGGAGAAG
CCCCCTCTGCCTGTGTATACTCAGTTCTATTTCTTCAATGTCACCAATCCAGAGGAGATCCTCAGAGGGGAGACCCCTCGGGTGGAAGAA
GTGGGGCCATACACCTACAGGGAACTCAGAAACAAAGCAAATATTCAATTTGGAGATAATGGAACAACAATATCTGCTGTTAGCAACAAG
GCCTATGTTTTTGAACGAGACCAATCTGTTGGAGACCCTAAAATTGACTTAATTAGAACATTAAATATTCCTGTATTGACTGTCATAGAG
TGGTCCCAGGTGCACTTCCTCAGGGAGATCATCGAGGCCATGTTGAAAGCCTATCAGCAGAAGCTCTTTGTGACTCACACAGTTGACGAA
TTGCTCTGGGGCTACAAAGATGAAATCTTGTCCCTTATCCATGTTTTCAGGCCCGATATCTCTCCCTATTTTGGCCTATTCTATGAGAAA
AATGGGACTAATGATGGAGACTATGTTTTTCTAACTGGAGAAGACAGTTACCTTAACTTTACAAAAATTGTGGAATGGAATGGGAAAACG
TCACTTGACTGGTGGATAACAGACAAGTGCAATATGATTAATGGAACAGATGGAGATTCTTTTCACCCACTAATAACCAAAGATGAGGTC
CTTTATGTCTTCCCATCTGACTTTTGCAGGTCAGTGTATATTACTTTCAGTGACTATGAGAGTGTACAGGGACTGCCTGCCTTTCGGTAT
AAAGTTCCTGCAGAAATATTAGCCAATACGTCAGACAATGCCGGCTTCTGTATACCTGAGGGAAACTGCCTGGGCTCAGGAGTTCTGAAT
GTCAGCATCTGCAAGAATGGTGCACCCATCATTATGTCTTTCCCACACTTTTACCAAGCAGATGAGAGGTTTGTTTCTGCCATAGAAGGC
ATGCACCCAAATCAGGAAGACCATGAGACATTTGTGGACATTAATCCTTTGACTGGAATAATCCTAAAAGCAGCCAAGAGGTTCCAAATC
AACATTTATGTCAAAAAATTAGATGACTTTGTTGAAACGGGAGACATTAGAACCATGGTTTTCCCAGTGATGTACCTCAATGAGAGTGTT
CACATTGATAAAGAGACGGCGAGTCGACTGAAGTCTATGATTAACACTACTTTGATCATCACCAACATACCCTACATCATCATGGCGCTG
GGTGTGTTCTTTGGTTTGGTTTTTACCTGGCTTGCATGCAAAGGACAGGGATCCATGGATGAGGGAACAGCGGATGAAAGAGCACCCCTC

>In-frame_SHROOM3_ENST00000296043_chr4_77692051_+_SCARB2_ENST00000452464_chr4_77117017_-_6513nt
ATGATGAGGACCACTGAAGACTTCCACAAGCCTAGTGCCACATTAAACTCTAACACGGCCACCAAGGGAAGGTACATTTATCTGGAGGCA
TTCCTGGAGGGAGGAGCTCCCTGGGGTTTTACTCTAAAGGGTGGCCTGGAGCACGGAGAACCATTAATCATCTCTAAGGTCGAAGAAGGG
GGCAAAGCAGACACCCTGAGCTCCAAACTGCAGGCTGGGGATGAGGTTGTGCACATCAATGAGGTGACTCTGAGCAGCTCCAGAAAGGAG
GCAGTTTCCCTGGTGAAAGGATCCTACAAGACCCTCAGGCTGGTAGTGCGCAGAGATGTGTGCACAGACCCAGGCCATGCAGATACTGGT
GCCTCTAACTTCGTCAGCCCAGAACACCTCACCTCTGGCCCCCAGCACAGGAAAGCAGCGTGGTCAGGAGGGGTTAAACTTCGGCTGAAG
CACAGGCGCAGTGAGCCTGCAGGCCGACCTCACTCGTGGCACACAACTAAATCTGGGGAGAAGCAACCCGATGCCAGCATGATGCAGATA
TCTCAGGGTATGATCGGCCCTCCTTGGCACCAAAGCTACCATTCCAGCTCCTCTACTAGTGACCTCTCCAACTATGACCATGCTTATCTA
AGGCGGAGCCCTGACCAGTGCAGCTCCCAGGGGAGCATGGAGAGCCTGGAGCCCAGTGGGGCATACCCACCCTGTCATCTTTCCCCTGCC
AAGTCCACCGGCAGCATTGACCAGCTCAGCCACTTCCATAACAAGAGAGACTCGGCTTACAGCTCTTTCTCCACCAGTTCTAGCATCCTA
GAGTATCCACACCCTGGCATCTCTGGCCGGGAGCGTTCAGGCTCCATGGACAATACTTCTGCTCGAGGTGGCCTCCTCGAAGGGATGAGG
CAGGCAGATATTCGCTATGTCAAGACAGTCTATGACACCCGGAGGGGAGTCTCAGCAGAGTATGAGGTGAACTCTTCAGCCCTGCTGCTT
CAAGGTAGGGAGGCCCGAGCCTCAGCAAATGGTCAGGGCTATGATAAATGGTCTAATATTCCTCGGGGCAAGGGAGTGCCACCCCCATCC
TGGAGCCAGCAGTGCCCCAGTTCCTTGGAGACTGCCACGGACAACCTTCCTCCTAAGGTGGGTGCACCCCTGCCTCCAGCTCGGAGTGAC
AGTTACGCAGCATTTCGGCACCGTGAGCGGCCCAGCTCCTGGTCTAGCCTTGATCAGAAACGGCTCTGCCGGCCTCAGGCAAACTCTTTA
GGCTCCCTGAAGTCTCCATTCATAGAGGAGCAGCTGCATACTGTGCTGGAGAAGAGTCCAGAGAACAGCCCCCCAGTGAAGCCCAAGCAT
AACTATACCCAGAAGGCCCAACCTGGCCAACCTCTGCTGCCGACCAGCATCTACCCGGTACCTTCCCTGGAGCCACACTTTGCCCAGGTG
CCTCAGCCTTCTGTGAGTAGCAACGGTATGCTCTACCCTGCACTGGCCAAGGAGAGTGGATACATAGCCCCTCAGGGAGCATGCAACAAG
ATGGCTACCATTGATGAGAATGGGAACCAGAATGGATCTGGCAGGCCTGGGTTTGCCTTCTGCCAGCCCTTAGAACATGACTTGCTGTCC
CCAGTGGAGAAGAAACCAGAAGCTACAGCCAAGTATGTCCCCTCCAAAGTCCATTTCTGTTCAGTGCCTGAAAATGAGGAGGATGCCTCC
CTGAAGAGACATCTCACACCTCCCCAAGGCAACAGCCCACATTCCAATGAGAGAAAGAGCACCCACAGTAACAAACCATCTTCTCATCCC
CACAGCCTCAAATGCCCTCAGGCTCAGGCCTGGCAAGCGGGTGAAGACAAGAGATCTTCCAGGCTCTCAGAGCCCTGGGAGGGCGATTTC
CAGGAAGACCACAATGCCAACCTCTGGAGGAGGCTGGAGAGAGAAGGCCTAGGCCAGAGCCTGTCAGGCAACTTTGGCAAGACCAAGTCA
GCCTTCTCATCTCTCCAGAACATTCCTGAGAGTCTGAGAAGACACAGCAGCCTGGAGCTAGGCCGGGGAACCCAGGAGGGTTACCCCGGG
GGCAGGCCCACCTGTGCAGTCAACACCAAGGCAGAAGACCCTGGGAGGAAAGCCGCTCCTGACCTCGGGAGCCATCTGGACCGGCAGGTT
TCCTACCCGCGGCCCGAGGGGAGGACCGGTGCCTCGGCTTCTTTCAACAGCACAGACCCAAGTCCCGAAGAGCCGCCTGCCCCCTCGCAC
CCGCACACATCCAGTCTGGGCCGGAGGGGGCCCGGCCCAGGCAGCGCCTCGGCTCTTCAGGGCTTTCAGTACGGGAAGCCCCACTGCTCG
GTGCTGGAGAAGGTCTCCAAATTCGAGCAGCGAGAGCAAGGGAGCCAGAGACCGAGTGTGGGCGGCTCTGGTTTTGGCCATAACTATAGG
CCCCACAGGACCGTCTCAACTTCCAGTACTTCTGGGAATGACTTCGAGGAGACAAAAGCACACATTCGTTTCTCTGAGTCAGCTGAACCC
CTAGGCAACGGGGAGCAGCACTTCAAAAACGGGGAGCTGAAGTTGGAAGAGGCTTCCCGGCAGCCCTGCGGTCAGCAGCTGAGCGGAGGA
GCGTCGGACAGCGGCCGTGGCCCCCAGAGGCCGGACGCTCGGCTCCTCCGTAGCCAGAGCACCTTCCAGCTCTCCAGCGAGCCAGAGAGG
GAGCCCGAGTGGCGGGACAGGCCCGGCTCGCCCGAATCGCCCCTGCTGGATGCCCCCTTCAGCCGCGCCTACCGGAACAGCATCAAGGAC
GCACAGTCCCGTGTCTTGGGGGCCACCTCCTTTCGACGTCGAGACCTGGAGCTGGGGGCGCCCGTGGCGTCGAGGTCCTGGCGGCCACGG
CCTTCCTCGGCCCACGTGGGGCTGCGGAGCCCCGAGGCGTCGGCCTCCGCCTCCCCGCACACGCCCCGGGAGCGGCACAGCGTGACCCCT
GCTGAGGGCGACCTGGCCAGGCCCGTGCCCCCTGCCGCCCGGAGAGGTGCTCGCCGGCGCCTGACTCCCGAGCAGAAGAAGCGCTCCTAC
TCGGAGCCCGAGAAGATGAACGAGGTGGGGATCGTGGAGGAGGCCGAACCGGCACCCCTGGGCCCGCAGAGAAATGGGATGCGTTTCCCG
GAGAGCAGCGTGGCCGACCGGCGCCGTCTCTTCGAGCGCGATGGCAAGGCCTGCTCCACGCTCAGCCTGTCGGGGCCCGAGCTGAAGCAG
TTCCAGCAGAGCGCCCTGGCGGACTACATCCAGCGCAAGACCGGCAAGCGGCCTACCTCCGCCGCCGGCTGCAGCCTCCAGGAGCCCGGG
CCACTGCGTGAGCGCGCCCAGAGTGCCTACCTCCAGCCCGGCCCCGCGGCGCTCGAAGGCTCCGGCCTCGCCTCGGCCTCCAGCTTGAGC
TCACTGCGGGAGCCCAGCCTGCAGCCCCGCAGGGAGGCCACGCTCCTGCCGGCCACAGTTGCAGAAACCCAGCAGGCTCCCCGAGATCGC
AGCAGCTCCTTCGCCGGTGGCCGCCGCCTCGGGGAACGGCGACGCGGGGACCTGCTTAGCGGAGCAAACGGTGGAACAAGGGGCACCCAG
AGAGGGGATGAGACCCCCAGGGAGCCATCCTCCTGGGGGGCCAGGGCCGGGAAGTCCATGTCGGCCGAGGACCTGCTGGAACGCTCGGAC
GTCCTTGCGGGCCCTGTCCATGTGAGGTCCAGGTCATCTCCCGCCACCGCAGACAAGCGCCAGGATGTGCTTTTGGGGCAAGACAGTGGC
TTTGGTCTTGTGAAGGATCCATGTTATTTGGCTGGTCCTGGATCTAGGTCACTCAGTTGTTCAGAAAGAGGCCAAGAAGAGATGCTGCCG
CTCTTCCACCATCTCACCCCTCGTTGGGGTGGTTCAGGCTGCAAAGCCATTGGTGATTCCTCCGTTCCTAGTGAATGTCCTGGAACCCTG
GACCATCAGAGGCAAGCCAGTAGGACACCCTGCCCCAGGCCACCACTGGCAGGAACGCAAGGGCTGGTCACAGACACCAGGGCTGCACCC
CTGACCCCAATTGGCACCCCTCTGCCTTCAGCCATTCCCTCTGGCTACTGCTCACAGGACGGTCAGACAGGGCGACAGCCTCTCCCGCCC
TACACCCCTGCCATGATGCACAGAAGCAATGGTCACACCCTGACCCAGCCTCCCGGTCCAAGAGGCTGTGAGGGCGATGGCCCAGAGCAT
GGGGTAGAAGAGGGAACGAGGAAGAGGGTCTCGCTGCCTCAGTGGCCACCTCCTTCTCGAGCAAAGTGGGCCCACGCAGCCAGAGAGGAC
AGCCTTCCTGAGGAATCCTCAGCCCCTGATTTTGCAAACCTGAAGCACTATCAAAAACAGCAGAGTCTTCCAAGTTTATGCAGCACTTCT
GACCCAGACACACCTCTTGGGGCCCCGAGCACTCCAGGGAGGATCTCCCTCCGAATATCTGAGTCTGTCCTGCGGGACTCCCCGCCACCT
CATGAGGATTATGAAGACGAAGTGTTTGTGAGGGATCCGCACCCCAAGGCCACGTCCAGCCCCACATTTGAACCTCTTCCCCCACCCCCA
CCTCCTCCACCGAGTCAGGAAACCCCGGTGTATAGCATGGATGACTTCCCTCCACCTCCTCCCCACACTGTATGTGAGGCGCAGCTGGAC
AGTGAGGATCCCGAGGGGCCACGCCCCAGCTTCAACAAACTTTCTAAAGTGACAATTGCAAGGGAAAGGCACATGCCTGGTGCAGCCCAT
GTGGTAGGTAGTCAGACACTGGCTTCCAGACTCCAAACTTCTATCAAGGGTTCAGAGGCTGAGTCCACACCACCCTCCTTCATGAGCGTT
CACGCCCAACTTGCTGGGTCTCTTGGTGGGCAGCCAGCACCCATCCAGACTCAAAGCCTCAGCCATGATCCAGTCAGTGGAACTCAGGGT
TTAGAAAAGAAAGTCAGTCCTGATCCTCAGAAGAGTTCAGAAGACATCAGAACAGAGGCTTTGGCCAAGGAAATTGTCCACCAAGACAAA
TCTCTAGCAGACATTTTGGATCCAGACTCCAGGCTGAAGACAACAATGGACCTGATGGAAGGTTTGTTTCCCCGAGATGTGAACTTGCTG
AAGGAAAACAGTGTAAAGAGGAAGGCCATACAGAGAACTGTCAGCTCTTCAGGATGTGAAGGCAAGAGGAATGAAGACAAGGAAGCAGTG
AGCATGTTGGTTAACTGCCCTGCCTACTACAGTGTGTCTGCTCCCAAGGCTGAGCTACTGAACAAAATCAAAGAGATGCCAGCAGAAGTG
AATGAGGAAGAGGAACAGGCAGATGTCAATGAAAAGAAGGCTGAGCTCATTGGAAGTCTCACCCACAAGCTGGAGACCCTCCAGGAGGCG
AAGGGGAGCCTGCTCACGGACATCAAGCTCAACAACGCCCTGGGAGAAGAGGTGGAGGCTCTGATCAGCGAGCTCTGCAAGCCCAATGAG
TTTGACAAGTATAGGATGTTCATAGGGGATTTGGACAAGGTGGTCAACCTGCTGCTCTCCCTCTCGGGGCGTCTAGCCCGTGTTGAGAAT
GTCCTTAGCGGCCTTGGTGAAGATGCCAGTAATGAAGAAAGGAAAATTGTGTTAAGGAATGGTACTGAGGCATTTGACTCCTGGGAGAAG
CCCCCTCTGCCTGTGTATACTCAGTTCTATTTCTTCAATGTCACCAATCCAGAGGAGATCCTCAGAGGGGAGACCCCTCGGGTGGAAGAA
GTGGGGCCATACACCTACAGGTCACTTGACTGGTGGATAACAGACAAGTGCAATATGATTAATGGAACAGATGGAGATTCTTTTCACCCA
CTAATAACCAAAGATGAGGTCCTTTATGTCTTCCCATCTGACTTTTGCAGGTCAGTGTATATTACTTTCAGTGACTATGAGAGTGTACAG
GGACTGCCTGCCTTTCGGTATAAAGTTCCTGCAGAAATATTAGCCAATACGTCAGACAATGCCGGCTTCTGTATACCTGAGGGAAACTGC
CTGGGCTCAGGAGTTCTGAATGTCAGCATCTGCAAGAATGGTGCACCCATCATTATGTCTTTCCCACACTTTTACCAAGCAGATGAGAGG
TTTGTTTCTGCCATAGAAGGCATGCACCCAAATCAGGAAGACCATGAGACATTTGTGGACATTAATCCTTTGACTGGAATAATCCTAAAA
GCAGCCAAGAGGTTCCAAATCAACATTTATGTCAAAAAATTAGATGACTTTGTTGAAACGGGAGACATTAGAACCATGGTTTTCCCAGTG
ATGTACCTCAATGAGAGTGTTCACATTGATAAAGAGACGGCGAGTCGACTGAAGTCTATGATTAACACTACTTTGATCATCACCAACATA
CCCTACATCATCATGGCGCTGGGTGTGTTCTTTGGTTTGGTTTTTACCTGGCTTGCATGCAAAGGACAGGGATCCATGGATGAGGGAACA


* Fusion transcript sequences (Full-length transcript).
>In-frame_SHROOM3_ENST00000296043_chr4_77692051_+_SCARB2_ENST00000264896_chr4_77117017_-_10871nt
GTTATTAACTGTAAGACTGTTTGAATTGTCAGGTCTTTGTGGTGAGCTGAATTCTGCATGGCAGTGCTTACTGTGCAGAAAGGTTGCAAT
GCCTCACTTTGCCTTAATCCATGTTCCTCTAACTTCCTTACTCTTTCTCTCAAGAGGAGGCAAGTGGCTGTGGCGGCCGCAGCAGTGGCT
GATCATCACTGAAAATACCAAAGAAAAGAACTGAGCTGCCTCCTTCATATTTTTTCCATTGAGGATTAATTTACCGTGCTTTTTCATTTT
CTCTACATCCTGCAAAAGTTTTTTTCTCTCCTAAGAAACAAACTATGAACTGATTGTTGAAAAAAAGAAGTAAAAAGTTTTAGCACAGCT
TCTCTGTCTCTTCGGGACAAGTTAGAAAATTCTGAAGTGAGCCGAAGCATAGTAAGTGCTTTCTTTCTTTTTAAGCTACTTCTGGGGAGG
GAGGAGGCTATTGTAATGGTAAATTTCACTCCGAGAGGAAGAAAGGGTTGATAATCAATCAAAAATGAGGTATTCCTTTGAGTATTTGTG
ATTTTCTTACTATATTGTAAGATGCTTTTAATTTTCTCTGTAAAATAGGCAGAAATGGTTTTAGTGTGTGTATGTGTGAAATAAAAGCTC
AGAAAAGCAATCTTCAGAGCGCCACTGAAGGAAGTTTTGACGAACGGAGTAGAGATGTATACCACTTGGGGGCTTCAGTGAGAACCCAGA
ATTCCTGGAGGAGGATTTACATTCAGAAATGTTGAAGTGAAAATTCCTTCTGGTTCAGCATCTTGGAGTTCAGCTTGGAAGAACATTTTA
CGTATGGAAGAATTTGCTTCTCCAAACCTCTCTTTTGGCCATTGTGTGTCCTGAAGGATGGGACAACTTGTGCTGTAGAAGCACTGCTTG
CCTGAGTTTGCTTCAGGCATTTTAAATTTAACTTGAGGGATCATGTGTTTGGCATGATGAGGACCACTGAAGACTTCCACAAGCCTAGTG
CCACATTAAACTCTAACACGGCCACCAAGGGAAGGTACATTTATCTGGAGGCATTCCTGGAGGGAGGAGCTCCCTGGGGTTTTACTCTAA
AGGGTGGCCTGGAGCACGGAGAACCATTAATCATCTCTAAGGTCGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCCAAACTGCAGGCTG
GGGATGAGGTTGTGCACATCAATGAGGTGACTCTGAGCAGCTCCAGAAAGGAGGCAGTTTCCCTGGTGAAAGGATCCTACAAGACCCTCA
GGCTGGTAGTGCGCAGAGATGTGTGCACAGACCCAGGCCATGCAGATACTGGTGCCTCTAACTTCGTCAGCCCAGAACACCTCACCTCTG
GCCCCCAGCACAGGAAAGCAGCGTGGTCAGGAGGGGTTAAACTTCGGCTGAAGCACAGGCGCAGTGAGCCTGCAGGCCGACCTCACTCGT
GGCACACAACTAAATCTGGGGAGAAGCAACCCGATGCCAGCATGATGCAGATATCTCAGGGTATGATCGGCCCTCCTTGGCACCAAAGCT
ACCATTCCAGCTCCTCTACTAGTGACCTCTCCAACTATGACCATGCTTATCTAAGGCGGAGCCCTGACCAGTGCAGCTCCCAGGGGAGCA
TGGAGAGCCTGGAGCCCAGTGGGGCATACCCACCCTGTCATCTTTCCCCTGCCAAGTCCACCGGCAGCATTGACCAGCTCAGCCACTTCC
ATAACAAGAGAGACTCGGCTTACAGCTCTTTCTCCACCAGTTCTAGCATCCTAGAGTATCCACACCCTGGCATCTCTGGCCGGGAGCGTT
CAGGCTCCATGGACAATACTTCTGCTCGAGGTGGCCTCCTCGAAGGGATGAGGCAGGCAGATATTCGCTATGTCAAGACAGTCTATGACA
CCCGGAGGGGAGTCTCAGCAGAGTATGAGGTGAACTCTTCAGCCCTGCTGCTTCAAGGTAGGGAGGCCCGAGCCTCAGCAAATGGTCAGG
GCTATGATAAATGGTCTAATATTCCTCGGGGCAAGGGAGTGCCACCCCCATCCTGGAGCCAGCAGTGCCCCAGTTCCTTGGAGACTGCCA
CGGACAACCTTCCTCCTAAGGTGGGTGCACCCCTGCCTCCAGCTCGGAGTGACAGTTACGCAGCATTTCGGCACCGTGAGCGGCCCAGCT
CCTGGTCTAGCCTTGATCAGAAACGGCTCTGCCGGCCTCAGGCAAACTCTTTAGGCTCCCTGAAGTCTCCATTCATAGAGGAGCAGCTGC
ATACTGTGCTGGAGAAGAGTCCAGAGAACAGCCCCCCAGTGAAGCCCAAGCATAACTATACCCAGAAGGCCCAACCTGGCCAACCTCTGC
TGCCGACCAGCATCTACCCGGTACCTTCCCTGGAGCCACACTTTGCCCAGGTGCCTCAGCCTTCTGTGAGTAGCAACGGTATGCTCTACC
CTGCACTGGCCAAGGAGAGTGGATACATAGCCCCTCAGGGAGCATGCAACAAGATGGCTACCATTGATGAGAATGGGAACCAGAATGGAT
CTGGCAGGCCTGGGTTTGCCTTCTGCCAGCCCTTAGAACATGACTTGCTGTCCCCAGTGGAGAAGAAACCAGAAGCTACAGCCAAGTATG
TCCCCTCCAAAGTCCATTTCTGTTCAGTGCCTGAAAATGAGGAGGATGCCTCCCTGAAGAGACATCTCACACCTCCCCAAGGCAACAGCC
CACATTCCAATGAGAGAAAGAGCACCCACAGTAACAAACCATCTTCTCATCCCCACAGCCTCAAATGCCCTCAGGCTCAGGCCTGGCAAG
CGGGTGAAGACAAGAGATCTTCCAGGCTCTCAGAGCCCTGGGAGGGCGATTTCCAGGAAGACCACAATGCCAACCTCTGGAGGAGGCTGG
AGAGAGAAGGCCTAGGCCAGAGCCTGTCAGGCAACTTTGGCAAGACCAAGTCAGCCTTCTCATCTCTCCAGAACATTCCTGAGAGTCTGA
GAAGACACAGCAGCCTGGAGCTAGGCCGGGGAACCCAGGAGGGTTACCCCGGGGGCAGGCCCACCTGTGCAGTCAACACCAAGGCAGAAG
ACCCTGGGAGGAAAGCCGCTCCTGACCTCGGGAGCCATCTGGACCGGCAGGTTTCCTACCCGCGGCCCGAGGGGAGGACCGGTGCCTCGG
CTTCTTTCAACAGCACAGACCCAAGTCCCGAAGAGCCGCCTGCCCCCTCGCACCCGCACACATCCAGTCTGGGCCGGAGGGGGCCCGGCC
CAGGCAGCGCCTCGGCTCTTCAGGGCTTTCAGTACGGGAAGCCCCACTGCTCGGTGCTGGAGAAGGTCTCCAAATTCGAGCAGCGAGAGC
AAGGGAGCCAGAGACCGAGTGTGGGCGGCTCTGGTTTTGGCCATAACTATAGGCCCCACAGGACCGTCTCAACTTCCAGTACTTCTGGGA
ATGACTTCGAGGAGACAAAAGCACACATTCGTTTCTCTGAGTCAGCTGAACCCCTAGGCAACGGGGAGCAGCACTTCAAAAACGGGGAGC
TGAAGTTGGAAGAGGCTTCCCGGCAGCCCTGCGGTCAGCAGCTGAGCGGAGGAGCGTCGGACAGCGGCCGTGGCCCCCAGAGGCCGGACG
CTCGGCTCCTCCGTAGCCAGAGCACCTTCCAGCTCTCCAGCGAGCCAGAGAGGGAGCCCGAGTGGCGGGACAGGCCCGGCTCGCCCGAAT
CGCCCCTGCTGGATGCCCCCTTCAGCCGCGCCTACCGGAACAGCATCAAGGACGCACAGTCCCGTGTCTTGGGGGCCACCTCCTTTCGAC
GTCGAGACCTGGAGCTGGGGGCGCCCGTGGCGTCGAGGTCCTGGCGGCCACGGCCTTCCTCGGCCCACGTGGGGCTGCGGAGCCCCGAGG
CGTCGGCCTCCGCCTCCCCGCACACGCCCCGGGAGCGGCACAGCGTGACCCCTGCTGAGGGCGACCTGGCCAGGCCCGTGCCCCCTGCCG
CCCGGAGAGGTGCTCGCCGGCGCCTGACTCCCGAGCAGAAGAAGCGCTCCTACTCGGAGCCCGAGAAGATGAACGAGGTGGGGATCGTGG
AGGAGGCCGAACCGGCACCCCTGGGCCCGCAGAGAAATGGGATGCGTTTCCCGGAGAGCAGCGTGGCCGACCGGCGCCGTCTCTTCGAGC
GCGATGGCAAGGCCTGCTCCACGCTCAGCCTGTCGGGGCCCGAGCTGAAGCAGTTCCAGCAGAGCGCCCTGGCGGACTACATCCAGCGCA
AGACCGGCAAGCGGCCTACCTCCGCCGCCGGCTGCAGCCTCCAGGAGCCCGGGCCACTGCGTGAGCGCGCCCAGAGTGCCTACCTCCAGC
CCGGCCCCGCGGCGCTCGAAGGCTCCGGCCTCGCCTCGGCCTCCAGCTTGAGCTCACTGCGGGAGCCCAGCCTGCAGCCCCGCAGGGAGG
CCACGCTCCTGCCGGCCACAGTTGCAGAAACCCAGCAGGCTCCCCGAGATCGCAGCAGCTCCTTCGCCGGTGGCCGCCGCCTCGGGGAAC
GGCGACGCGGGGACCTGCTTAGCGGAGCAAACGGTGGAACAAGGGGCACCCAGAGAGGGGATGAGACCCCCAGGGAGCCATCCTCCTGGG
GGGCCAGGGCCGGGAAGTCCATGTCGGCCGAGGACCTGCTGGAACGCTCGGACGTCCTTGCGGGCCCTGTCCATGTGAGGTCCAGGTCAT
CTCCCGCCACCGCAGACAAGCGCCAGGATGTGCTTTTGGGGCAAGACAGTGGCTTTGGTCTTGTGAAGGATCCATGTTATTTGGCTGGTC
CTGGATCTAGGTCACTCAGTTGTTCAGAAAGAGGCCAAGAAGAGATGCTGCCGCTCTTCCACCATCTCACCCCTCGTTGGGGTGGTTCAG
GCTGCAAAGCCATTGGTGATTCCTCCGTTCCTAGTGAATGTCCTGGAACCCTGGACCATCAGAGGCAAGCCAGTAGGACACCCTGCCCCA
GGCCACCACTGGCAGGAACGCAAGGGCTGGTCACAGACACCAGGGCTGCACCCCTGACCCCAATTGGCACCCCTCTGCCTTCAGCCATTC
CCTCTGGCTACTGCTCACAGGACGGTCAGACAGGGCGACAGCCTCTCCCGCCCTACACCCCTGCCATGATGCACAGAAGCAATGGTCACA
CCCTGACCCAGCCTCCCGGTCCAAGAGGCTGTGAGGGCGATGGCCCAGAGCATGGGGTAGAAGAGGGAACGAGGAAGAGGGTCTCGCTGC
CTCAGTGGCCACCTCCTTCTCGAGCAAAGTGGGCCCACGCAGCCAGAGAGGACAGCCTTCCTGAGGAATCCTCAGCCCCTGATTTTGCAA
ACCTGAAGCACTATCAAAAACAGCAGAGTCTTCCAAGTTTATGCAGCACTTCTGACCCAGACACACCTCTTGGGGCCCCGAGCACTCCAG
GGAGGATCTCCCTCCGAATATCTGAGTCTGTCCTGCGGGACTCCCCGCCACCTCATGAGGATTATGAAGACGAAGTGTTTGTGAGGGATC
CGCACCCCAAGGCCACGTCCAGCCCCACATTTGAACCTCTTCCCCCACCCCCACCTCCTCCACCGAGTCAGGAAACCCCGGTGTATAGCA
TGGATGACTTCCCTCCACCTCCTCCCCACACTGTATGTGAGGCGCAGCTGGACAGTGAGGATCCCGAGGGGCCACGCCCCAGCTTCAACA
AACTTTCTAAAGTGACAATTGCAAGGGAAAGGCACATGCCTGGTGCAGCCCATGTGGTAGGTAGTCAGACACTGGCTTCCAGACTCCAAA
CTTCTATCAAGGGTTCAGAGGCTGAGTCCACACCACCCTCCTTCATGAGCGTTCACGCCCAACTTGCTGGGTCTCTTGGTGGGCAGCCAG
CACCCATCCAGACTCAAAGCCTCAGCCATGATCCAGTCAGTGGAACTCAGGGTTTAGAAAAGAAAGTCAGTCCTGATCCTCAGAAGAGTT
CAGAAGACATCAGAACAGAGGCTTTGGCCAAGGAAATTGTCCACCAAGACAAATCTCTAGCAGACATTTTGGATCCAGACTCCAGGCTGA
AGACAACAATGGACCTGATGGAAGGTTTGTTTCCCCGAGATGTGAACTTGCTGAAGGAAAACAGTGTAAAGAGGAAGGCCATACAGAGAA
CTGTCAGCTCTTCAGGATGTGAAGGCAAGAGGAATGAAGACAAGGAAGCAGTGAGCATGTTGGTTAACTGCCCTGCCTACTACAGTGTGT
CTGCTCCCAAGGCTGAGCTACTGAACAAAATCAAAGAGATGCCAGCAGAAGTGAATGAGGAAGAGGAACAGGCAGATGTCAATGAAAAGA
AGGCTGAGCTCATTGGAAGTCTCACCCACAAGCTGGAGACCCTCCAGGAGGCGAAGGGGAGCCTGCTCACGGACATCAAGCTCAACAACG
CCCTGGGAGAAGAGGTGGAGGCTCTGATCAGCGAGCTCTGCAAGCCCAATGAGTTTGACAAGTATAGGATGTTCATAGGGGATTTGGACA
AGGTGGTCAACCTGCTGCTCTCCCTCTCGGGGCGTCTAGCCCGTGTTGAGAATGTCCTTAGCGGCCTTGGTGAAGATGCCAGTAATGAAG
AAAGGAAAATTGTGTTAAGGAATGGTACTGAGGCATTTGACTCCTGGGAGAAGCCCCCTCTGCCTGTGTATACTCAGTTCTATTTCTTCA
ATGTCACCAATCCAGAGGAGATCCTCAGAGGGGAGACCCCTCGGGTGGAAGAAGTGGGGCCATACACCTACAGGGAACTCAGAAACAAAG
CAAATATTCAATTTGGAGATAATGGAACAACAATATCTGCTGTTAGCAACAAGGCCTATGTTTTTGAACGAGACCAATCTGTTGGAGACC
CTAAAATTGACTTAATTAGAACATTAAATATTCCTGTATTGACTGTCATAGAGTGGTCCCAGGTGCACTTCCTCAGGGAGATCATCGAGG
CCATGTTGAAAGCCTATCAGCAGAAGCTCTTTGTGACTCACACAGTTGACGAATTGCTCTGGGGCTACAAAGATGAAATCTTGTCCCTTA
TCCATGTTTTCAGGCCCGATATCTCTCCCTATTTTGGCCTATTCTATGAGAAAAATGGGACTAATGATGGAGACTATGTTTTTCTAACTG
GAGAAGACAGTTACCTTAACTTTACAAAAATTGTGGAATGGAATGGGAAAACGTCACTTGACTGGTGGATAACAGACAAGTGCAATATGA
TTAATGGAACAGATGGAGATTCTTTTCACCCACTAATAACCAAAGATGAGGTCCTTTATGTCTTCCCATCTGACTTTTGCAGGTCAGTGT
ATATTACTTTCAGTGACTATGAGAGTGTACAGGGACTGCCTGCCTTTCGGTATAAAGTTCCTGCAGAAATATTAGCCAATACGTCAGACA
ATGCCGGCTTCTGTATACCTGAGGGAAACTGCCTGGGCTCAGGAGTTCTGAATGTCAGCATCTGCAAGAATGGTGCACCCATCATTATGT
CTTTCCCACACTTTTACCAAGCAGATGAGAGGTTTGTTTCTGCCATAGAAGGCATGCACCCAAATCAGGAAGACCATGAGACATTTGTGG
ACATTAATCCTTTGACTGGAATAATCCTAAAAGCAGCCAAGAGGTTCCAAATCAACATTTATGTCAAAAAATTAGATGACTTTGTTGAAA
CGGGAGACATTAGAACCATGGTTTTCCCAGTGATGTACCTCAATGAGAGTGTTCACATTGATAAAGAGACGGCGAGTCGACTGAAGTCTA
TGATTAACACTACTTTGATCATCACCAACATACCCTACATCATCATGGCGCTGGGTGTGTTCTTTGGTTTGGTTTTTACCTGGCTTGCAT
GCAAAGGACAGGGATCCATGGATGAGGGAACAGCGGATGAAAGAGCACCCCTCATTCGAACCTAAACATTGCCTTTGCTTGGTGAAGAAA
CTGTGTGAGCTGTCCTGACCTGGACGATGACGTGGGGAAACCCTCCACCTCCTTGCAGGCTTGTTGCCTGTTGAAAGAAGGAAAAAGACA
CGGCGCTGGCAAGTGATAGGAACATTCTGGCCAGAGGTTAAAGAGCAGGCTGACATGGCTGGCCATTAAGCTTTATAAAATCATGTGGGC
TCTGAAATTGTTCTTTTATGTGTCTAGCAAGTATTTAATAAACCCTTGTATAGTAATTTTGTTGTTGTTGGGTGCTGGTAGCTCCAGAAT
TTTGTGACCACTATTGTGGGTAAAATGTCTCTGCATCACTTGTTAATGCTACTGGTCTAACTTCATTCAGTATGCTTCATTCACCGAACT
TTGTGCTCAAAATGCGTATATACCATTTTATGTTGTATTCCTCCATTTCACTTGCAAAACAGAAGTAAATAAGAGTTCGGGACCCAGGGT
AAAATGGTAGCTTCATCCAATATATCATTCAAATGCATCTGATTTCTAAAACATATTACATTTTATGCTGATCTTCAGTTCATAATTCTT
CCAGGAAAACTCAGTCTTCCAACTGCAATAAAATACTGGGTAGAATCAAATGGGAAAGGGGTTGGGTGGGGCAATACCCATGAGTTGATA
GTGATAAGCTCCTAAGGATTTTTAACTTGTACTTTTGTGAACGAAGAGAATGCATAAATAATGTTGGTGAGGATAAAGTACAGATATTTC
ATGTAGAATTAATTGCTAGTTATGATGCTTGTGGATAGTTAACTGTTTTTTTTTTAGTCAAAATGATCATGCTACGAAAAGATGCTTCTG
AGAGAATGTAATGAGTAACTGATTTTTCTTCCTGAGTCGCCCTTGCCAAATATGTTACTGTATTAATTAATCTAATATTGAGTGATTATT
TGTAAAATTATGAATATGGGAAATCCATCTATCTACAGCCTAAGTTACACATAAGTTTCAGAAAGTCTGATTAGACTAAAGAGATATTTC
TTCTGGGACAGCCGCCTTCTTGGTAATTTTGAAGTTCTTTTTACAAGTTCCTTCCTCAGTTTCAGTTCTTTCCAGTGTTTTGTAGCTCAC
TGTCACTCACTGAATAGAGAAACGTGTGCCCTATACTTCCTGTGACAATCATTTTGCTGACAGAATGATGGATGTTTAAAATATTGCACA
AAGTACTTTAAAGAAAGGTCTGTTAGGACCAGAAGCAGAGACACCACTTTTCAAAGGACTTCTTGGTTTCAGCATAACCTAAGACAGGGA
ATTGGGAGCCATCATATGTCACAGTGTTCAGAATTCAAGCATATTTAAGGGCATTTTCTTTGATTCTCAAAGTTCAGCATTCATTTTGAA
TTGAGAAGCCTATACATTTAGCTGACAAAGTGCTTATAGAATTTCTTAACAACTGAACCATTCAAAAGGATTTTTTTTGTTTAAAACTGG
ATTTCAATGTAAGCAAATGAAGAAAAAAATATAGATTTCATTTCCATAGCTTCTTATCCCTGTATTGAGGTAATAAATTGTTTTACTGAC
AATTTTTCCTTTTTCTACACTAAAACAATATGTGATATATTTCCCCTCTTGAAGAGGCAATTCATTAAACTCTCAAATTTTCTATAGAAT
CAAGATAGAACCTTTAGATACTCCAACTCACCAAAATGTAAAAAAACTAACAAAAATATTTGGTCTTCAATAATGCTAAATATCTACATT
TTTAGAATTTATCAACATTTAACTAGATAATTGGGCATGTCTTAATTATGCATGTACTTATCCATACTAATAAAATTGACAATGCTAGTG
CATACTTATTGGTTTAGTCCTATTATCAGGATATAATCATCTGTGAGGAGGATATTTTAAATACTGTAAATGATAACAGTTAATGATATA
CACATTTAGACTGAGTTGCACACTGGCAGGGAGACCAAAAACATTACTTCCATACTTGTGTCATGATTCTTTTTTTTTTGAGAGAGTCTC
ACTCTGTCGCCAGGCTGGAGTACAGTGGCATGATCTCGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCAATTCTCCTGCCTCAGCCA
CCCAAGTAGCTGGGACTACAGGTGCGTGCCACCACGCCCAGCTAAATTTTGTATTTTTAGTGGAGACGGGGTTTCACCATGTTGGCCAGG
ATGGTCTCAATCTCCTGACCCTGCGATCTGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTAAGCCACCGGGCCTGGCCTGTT
TTATGATTCTTAATAGTTACTTGGTTTAAATCACATTTGATACTATCCTTCTGAAAAGTCTGAGACAGATCTACAAACTACAGTCAAAAT
TATAGATTAAGAGGAATGAATGCACCTATTTGGCTTTAAGTTGAAGATGAATTATTTCTCATGCTCATTTTCTTGCGGCAGTTATCTTAG
AAAGACCCCCAAAGGCTTTGTGATTGTAAGCACTGTCATGATCACAGAATGCAAGCTTCTGGTACCATGATCCTCAACTTAGAGAGGAAG
AAACCAAGACAGAGAGCTTAACTCACTTCTCTCAGGGAAAATTAGGAGTTGAGCACAGGACAGGAAATGGGCTTTGCCACTTTTAGCTCC
AGGCTTTTCTAACCAGACTTGATTTCCTCATGTTCTAGAAAGATCACTAATGGTCAAGTGGAACAAGCACTACACGACTAACCCCTATTG
GGGTTTTTAACTTAAGGGAGGCTAATTTTTAATTTAAACTGCTCGAGATATGAGTTCTGCAAAAGGTGGTCCGCATCCTTGGCCCTCTGG
ACATTATCACTAAATTGCTTGTGCCTGTTAACAAGAATACTGACCAGAATGCTCTTCATGTAGCTTATACAGTTGGTTCACTTCATGCGG

>In-frame_SHROOM3_ENST00000296043_chr4_77692051_+_SCARB2_ENST00000452464_chr4_77117017_-_7893nt
GTTATTAACTGTAAGACTGTTTGAATTGTCAGGTCTTTGTGGTGAGCTGAATTCTGCATGGCAGTGCTTACTGTGCAGAAAGGTTGCAAT
GCCTCACTTTGCCTTAATCCATGTTCCTCTAACTTCCTTACTCTTTCTCTCAAGAGGAGGCAAGTGGCTGTGGCGGCCGCAGCAGTGGCT
GATCATCACTGAAAATACCAAAGAAAAGAACTGAGCTGCCTCCTTCATATTTTTTCCATTGAGGATTAATTTACCGTGCTTTTTCATTTT
CTCTACATCCTGCAAAAGTTTTTTTCTCTCCTAAGAAACAAACTATGAACTGATTGTTGAAAAAAAGAAGTAAAAAGTTTTAGCACAGCT
TCTCTGTCTCTTCGGGACAAGTTAGAAAATTCTGAAGTGAGCCGAAGCATAGTAAGTGCTTTCTTTCTTTTTAAGCTACTTCTGGGGAGG
GAGGAGGCTATTGTAATGGTAAATTTCACTCCGAGAGGAAGAAAGGGTTGATAATCAATCAAAAATGAGGTATTCCTTTGAGTATTTGTG
ATTTTCTTACTATATTGTAAGATGCTTTTAATTTTCTCTGTAAAATAGGCAGAAATGGTTTTAGTGTGTGTATGTGTGAAATAAAAGCTC
AGAAAAGCAATCTTCAGAGCGCCACTGAAGGAAGTTTTGACGAACGGAGTAGAGATGTATACCACTTGGGGGCTTCAGTGAGAACCCAGA
ATTCCTGGAGGAGGATTTACATTCAGAAATGTTGAAGTGAAAATTCCTTCTGGTTCAGCATCTTGGAGTTCAGCTTGGAAGAACATTTTA
CGTATGGAAGAATTTGCTTCTCCAAACCTCTCTTTTGGCCATTGTGTGTCCTGAAGGATGGGACAACTTGTGCTGTAGAAGCACTGCTTG
CCTGAGTTTGCTTCAGGCATTTTAAATTTAACTTGAGGGATCATGTGTTTGGCATGATGAGGACCACTGAAGACTTCCACAAGCCTAGTG
CCACATTAAACTCTAACACGGCCACCAAGGGAAGGTACATTTATCTGGAGGCATTCCTGGAGGGAGGAGCTCCCTGGGGTTTTACTCTAA
AGGGTGGCCTGGAGCACGGAGAACCATTAATCATCTCTAAGGTCGAAGAAGGGGGCAAAGCAGACACCCTGAGCTCCAAACTGCAGGCTG
GGGATGAGGTTGTGCACATCAATGAGGTGACTCTGAGCAGCTCCAGAAAGGAGGCAGTTTCCCTGGTGAAAGGATCCTACAAGACCCTCA
GGCTGGTAGTGCGCAGAGATGTGTGCACAGACCCAGGCCATGCAGATACTGGTGCCTCTAACTTCGTCAGCCCAGAACACCTCACCTCTG
GCCCCCAGCACAGGAAAGCAGCGTGGTCAGGAGGGGTTAAACTTCGGCTGAAGCACAGGCGCAGTGAGCCTGCAGGCCGACCTCACTCGT
GGCACACAACTAAATCTGGGGAGAAGCAACCCGATGCCAGCATGATGCAGATATCTCAGGGTATGATCGGCCCTCCTTGGCACCAAAGCT
ACCATTCCAGCTCCTCTACTAGTGACCTCTCCAACTATGACCATGCTTATCTAAGGCGGAGCCCTGACCAGTGCAGCTCCCAGGGGAGCA
TGGAGAGCCTGGAGCCCAGTGGGGCATACCCACCCTGTCATCTTTCCCCTGCCAAGTCCACCGGCAGCATTGACCAGCTCAGCCACTTCC
ATAACAAGAGAGACTCGGCTTACAGCTCTTTCTCCACCAGTTCTAGCATCCTAGAGTATCCACACCCTGGCATCTCTGGCCGGGAGCGTT
CAGGCTCCATGGACAATACTTCTGCTCGAGGTGGCCTCCTCGAAGGGATGAGGCAGGCAGATATTCGCTATGTCAAGACAGTCTATGACA
CCCGGAGGGGAGTCTCAGCAGAGTATGAGGTGAACTCTTCAGCCCTGCTGCTTCAAGGTAGGGAGGCCCGAGCCTCAGCAAATGGTCAGG
GCTATGATAAATGGTCTAATATTCCTCGGGGCAAGGGAGTGCCACCCCCATCCTGGAGCCAGCAGTGCCCCAGTTCCTTGGAGACTGCCA
CGGACAACCTTCCTCCTAAGGTGGGTGCACCCCTGCCTCCAGCTCGGAGTGACAGTTACGCAGCATTTCGGCACCGTGAGCGGCCCAGCT
CCTGGTCTAGCCTTGATCAGAAACGGCTCTGCCGGCCTCAGGCAAACTCTTTAGGCTCCCTGAAGTCTCCATTCATAGAGGAGCAGCTGC
ATACTGTGCTGGAGAAGAGTCCAGAGAACAGCCCCCCAGTGAAGCCCAAGCATAACTATACCCAGAAGGCCCAACCTGGCCAACCTCTGC
TGCCGACCAGCATCTACCCGGTACCTTCCCTGGAGCCACACTTTGCCCAGGTGCCTCAGCCTTCTGTGAGTAGCAACGGTATGCTCTACC
CTGCACTGGCCAAGGAGAGTGGATACATAGCCCCTCAGGGAGCATGCAACAAGATGGCTACCATTGATGAGAATGGGAACCAGAATGGAT
CTGGCAGGCCTGGGTTTGCCTTCTGCCAGCCCTTAGAACATGACTTGCTGTCCCCAGTGGAGAAGAAACCAGAAGCTACAGCCAAGTATG
TCCCCTCCAAAGTCCATTTCTGTTCAGTGCCTGAAAATGAGGAGGATGCCTCCCTGAAGAGACATCTCACACCTCCCCAAGGCAACAGCC
CACATTCCAATGAGAGAAAGAGCACCCACAGTAACAAACCATCTTCTCATCCCCACAGCCTCAAATGCCCTCAGGCTCAGGCCTGGCAAG
CGGGTGAAGACAAGAGATCTTCCAGGCTCTCAGAGCCCTGGGAGGGCGATTTCCAGGAAGACCACAATGCCAACCTCTGGAGGAGGCTGG
AGAGAGAAGGCCTAGGCCAGAGCCTGTCAGGCAACTTTGGCAAGACCAAGTCAGCCTTCTCATCTCTCCAGAACATTCCTGAGAGTCTGA
GAAGACACAGCAGCCTGGAGCTAGGCCGGGGAACCCAGGAGGGTTACCCCGGGGGCAGGCCCACCTGTGCAGTCAACACCAAGGCAGAAG
ACCCTGGGAGGAAAGCCGCTCCTGACCTCGGGAGCCATCTGGACCGGCAGGTTTCCTACCCGCGGCCCGAGGGGAGGACCGGTGCCTCGG
CTTCTTTCAACAGCACAGACCCAAGTCCCGAAGAGCCGCCTGCCCCCTCGCACCCGCACACATCCAGTCTGGGCCGGAGGGGGCCCGGCC
CAGGCAGCGCCTCGGCTCTTCAGGGCTTTCAGTACGGGAAGCCCCACTGCTCGGTGCTGGAGAAGGTCTCCAAATTCGAGCAGCGAGAGC
AAGGGAGCCAGAGACCGAGTGTGGGCGGCTCTGGTTTTGGCCATAACTATAGGCCCCACAGGACCGTCTCAACTTCCAGTACTTCTGGGA
ATGACTTCGAGGAGACAAAAGCACACATTCGTTTCTCTGAGTCAGCTGAACCCCTAGGCAACGGGGAGCAGCACTTCAAAAACGGGGAGC
TGAAGTTGGAAGAGGCTTCCCGGCAGCCCTGCGGTCAGCAGCTGAGCGGAGGAGCGTCGGACAGCGGCCGTGGCCCCCAGAGGCCGGACG
CTCGGCTCCTCCGTAGCCAGAGCACCTTCCAGCTCTCCAGCGAGCCAGAGAGGGAGCCCGAGTGGCGGGACAGGCCCGGCTCGCCCGAAT
CGCCCCTGCTGGATGCCCCCTTCAGCCGCGCCTACCGGAACAGCATCAAGGACGCACAGTCCCGTGTCTTGGGGGCCACCTCCTTTCGAC
GTCGAGACCTGGAGCTGGGGGCGCCCGTGGCGTCGAGGTCCTGGCGGCCACGGCCTTCCTCGGCCCACGTGGGGCTGCGGAGCCCCGAGG
CGTCGGCCTCCGCCTCCCCGCACACGCCCCGGGAGCGGCACAGCGTGACCCCTGCTGAGGGCGACCTGGCCAGGCCCGTGCCCCCTGCCG
CCCGGAGAGGTGCTCGCCGGCGCCTGACTCCCGAGCAGAAGAAGCGCTCCTACTCGGAGCCCGAGAAGATGAACGAGGTGGGGATCGTGG
AGGAGGCCGAACCGGCACCCCTGGGCCCGCAGAGAAATGGGATGCGTTTCCCGGAGAGCAGCGTGGCCGACCGGCGCCGTCTCTTCGAGC
GCGATGGCAAGGCCTGCTCCACGCTCAGCCTGTCGGGGCCCGAGCTGAAGCAGTTCCAGCAGAGCGCCCTGGCGGACTACATCCAGCGCA
AGACCGGCAAGCGGCCTACCTCCGCCGCCGGCTGCAGCCTCCAGGAGCCCGGGCCACTGCGTGAGCGCGCCCAGAGTGCCTACCTCCAGC
CCGGCCCCGCGGCGCTCGAAGGCTCCGGCCTCGCCTCGGCCTCCAGCTTGAGCTCACTGCGGGAGCCCAGCCTGCAGCCCCGCAGGGAGG
CCACGCTCCTGCCGGCCACAGTTGCAGAAACCCAGCAGGCTCCCCGAGATCGCAGCAGCTCCTTCGCCGGTGGCCGCCGCCTCGGGGAAC
GGCGACGCGGGGACCTGCTTAGCGGAGCAAACGGTGGAACAAGGGGCACCCAGAGAGGGGATGAGACCCCCAGGGAGCCATCCTCCTGGG
GGGCCAGGGCCGGGAAGTCCATGTCGGCCGAGGACCTGCTGGAACGCTCGGACGTCCTTGCGGGCCCTGTCCATGTGAGGTCCAGGTCAT
CTCCCGCCACCGCAGACAAGCGCCAGGATGTGCTTTTGGGGCAAGACAGTGGCTTTGGTCTTGTGAAGGATCCATGTTATTTGGCTGGTC
CTGGATCTAGGTCACTCAGTTGTTCAGAAAGAGGCCAAGAAGAGATGCTGCCGCTCTTCCACCATCTCACCCCTCGTTGGGGTGGTTCAG
GCTGCAAAGCCATTGGTGATTCCTCCGTTCCTAGTGAATGTCCTGGAACCCTGGACCATCAGAGGCAAGCCAGTAGGACACCCTGCCCCA
GGCCACCACTGGCAGGAACGCAAGGGCTGGTCACAGACACCAGGGCTGCACCCCTGACCCCAATTGGCACCCCTCTGCCTTCAGCCATTC
CCTCTGGCTACTGCTCACAGGACGGTCAGACAGGGCGACAGCCTCTCCCGCCCTACACCCCTGCCATGATGCACAGAAGCAATGGTCACA
CCCTGACCCAGCCTCCCGGTCCAAGAGGCTGTGAGGGCGATGGCCCAGAGCATGGGGTAGAAGAGGGAACGAGGAAGAGGGTCTCGCTGC
CTCAGTGGCCACCTCCTTCTCGAGCAAAGTGGGCCCACGCAGCCAGAGAGGACAGCCTTCCTGAGGAATCCTCAGCCCCTGATTTTGCAA
ACCTGAAGCACTATCAAAAACAGCAGAGTCTTCCAAGTTTATGCAGCACTTCTGACCCAGACACACCTCTTGGGGCCCCGAGCACTCCAG
GGAGGATCTCCCTCCGAATATCTGAGTCTGTCCTGCGGGACTCCCCGCCACCTCATGAGGATTATGAAGACGAAGTGTTTGTGAGGGATC
CGCACCCCAAGGCCACGTCCAGCCCCACATTTGAACCTCTTCCCCCACCCCCACCTCCTCCACCGAGTCAGGAAACCCCGGTGTATAGCA
TGGATGACTTCCCTCCACCTCCTCCCCACACTGTATGTGAGGCGCAGCTGGACAGTGAGGATCCCGAGGGGCCACGCCCCAGCTTCAACA
AACTTTCTAAAGTGACAATTGCAAGGGAAAGGCACATGCCTGGTGCAGCCCATGTGGTAGGTAGTCAGACACTGGCTTCCAGACTCCAAA
CTTCTATCAAGGGTTCAGAGGCTGAGTCCACACCACCCTCCTTCATGAGCGTTCACGCCCAACTTGCTGGGTCTCTTGGTGGGCAGCCAG
CACCCATCCAGACTCAAAGCCTCAGCCATGATCCAGTCAGTGGAACTCAGGGTTTAGAAAAGAAAGTCAGTCCTGATCCTCAGAAGAGTT
CAGAAGACATCAGAACAGAGGCTTTGGCCAAGGAAATTGTCCACCAAGACAAATCTCTAGCAGACATTTTGGATCCAGACTCCAGGCTGA
AGACAACAATGGACCTGATGGAAGGTTTGTTTCCCCGAGATGTGAACTTGCTGAAGGAAAACAGTGTAAAGAGGAAGGCCATACAGAGAA
CTGTCAGCTCTTCAGGATGTGAAGGCAAGAGGAATGAAGACAAGGAAGCAGTGAGCATGTTGGTTAACTGCCCTGCCTACTACAGTGTGT
CTGCTCCCAAGGCTGAGCTACTGAACAAAATCAAAGAGATGCCAGCAGAAGTGAATGAGGAAGAGGAACAGGCAGATGTCAATGAAAAGA
AGGCTGAGCTCATTGGAAGTCTCACCCACAAGCTGGAGACCCTCCAGGAGGCGAAGGGGAGCCTGCTCACGGACATCAAGCTCAACAACG
CCCTGGGAGAAGAGGTGGAGGCTCTGATCAGCGAGCTCTGCAAGCCCAATGAGTTTGACAAGTATAGGATGTTCATAGGGGATTTGGACA
AGGTGGTCAACCTGCTGCTCTCCCTCTCGGGGCGTCTAGCCCGTGTTGAGAATGTCCTTAGCGGCCTTGGTGAAGATGCCAGTAATGAAG
AAAGGAAAATTGTGTTAAGGAATGGTACTGAGGCATTTGACTCCTGGGAGAAGCCCCCTCTGCCTGTGTATACTCAGTTCTATTTCTTCA
ATGTCACCAATCCAGAGGAGATCCTCAGAGGGGAGACCCCTCGGGTGGAAGAAGTGGGGCCATACACCTACAGGTCACTTGACTGGTGGA
TAACAGACAAGTGCAATATGATTAATGGAACAGATGGAGATTCTTTTCACCCACTAATAACCAAAGATGAGGTCCTTTATGTCTTCCCAT
CTGACTTTTGCAGGTCAGTGTATATTACTTTCAGTGACTATGAGAGTGTACAGGGACTGCCTGCCTTTCGGTATAAAGTTCCTGCAGAAA
TATTAGCCAATACGTCAGACAATGCCGGCTTCTGTATACCTGAGGGAAACTGCCTGGGCTCAGGAGTTCTGAATGTCAGCATCTGCAAGA
ATGGTGCACCCATCATTATGTCTTTCCCACACTTTTACCAAGCAGATGAGAGGTTTGTTTCTGCCATAGAAGGCATGCACCCAAATCAGG
AAGACCATGAGACATTTGTGGACATTAATCCTTTGACTGGAATAATCCTAAAAGCAGCCAAGAGGTTCCAAATCAACATTTATGTCAAAA
AATTAGATGACTTTGTTGAAACGGGAGACATTAGAACCATGGTTTTCCCAGTGATGTACCTCAATGAGAGTGTTCACATTGATAAAGAGA
CGGCGAGTCGACTGAAGTCTATGATTAACACTACTTTGATCATCACCAACATACCCTACATCATCATGGCGCTGGGTGTGTTCTTTGGTT
TGGTTTTTACCTGGCTTGCATGCAAAGGACAGGGATCCATGGATGAGGGAACAGCGGATGAAAGAGCACCCCTCATTCGAACCTAAACAT
TGCCTTTGCTTGGTGAAGAAACTGTGTGAGCTGTCCTGACCTGGACGATGACGTGGGGAAACCCTCCACCTCCTTGCAGGCTTGTTGCCT
GTTGAAAGAAGGAAAAAGACACGGCGCTGGCAAGTGATAGGAACATTCTGGCCAGAGGTTAAAGAGCAGGCTGACATGGCTGGCCATTAA
GCTTTATAAAATCATGTGGGCTCTGAAATTGTTCTTTTATGTGTCTAGCAAGTATTTAATAAACCCTTGTATAGTAATTTTGTTGTTGTT
GGGTGCTGGTAGCTCCAGAATTTTGTGACCACTATTGTGGGTAAAATGTCTCTGCATCACTTGTTAATGCTACTGGTCTAACTTCATTCA


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FusionGenePPI for SHROOM3_SCARB2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
SHROOM3SFN, SAAL1, YWHAB, UBTD1, CDK2, ILK, RPS6KA2, SIK2, RPS6KB2, MYH9, RAB32, SNW1, CDC5L, CDH1, TRIM25SCARB2THBS1, ATP6V1B1, NONO, DDX1, HSPD1, TAF15, ATP4A, GEM, LGALS8, NAALADL2, PTPRK, WISP3, NTRK1, SMC6, EIF2AK2, PRPF8, PNKD, MYOF, RHCG, VAMP3, SPAG9, GLMN, RAB27B, SCGB1D1, LMNA


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for SHROOM3_SCARB2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for SHROOM3_SCARB2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneSCARB2C0751779Action Myoclonus-Renal Failure Syndrome1CTD_human;ORPHANET;UNIPROT