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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 3359

FusionGeneSummary for ATP2B4_OPTC

check button Fusion gene summary
Fusion gene informationFusion gene name: ATP2B4_OPTC
Fusion gene ID: 3359
HgeneTgene
Gene symbol

ATP2B4

OPTC

Gene ID

493

26254

Gene nameATPase plasma membrane Ca2+ transporting 4opticin
SynonymsATP2B2|MXRA1|PMCA4|PMCA4b|PMCA4xOPT
Cytomap

1q32.1

1q32.1

Type of geneprotein-codingprotein-coding
Descriptionplasma membrane calcium-transporting ATPase 4ATPase, Ca++ transporting, plasma membrane 4matrix-remodeling-associated protein 1sarcolemmal calcium pumpopticinoculoglycan
Modification date2018052320180522
UniProtAcc

P23634

Q9UBM4

Ensembl transtripts involved in fusion geneENST00000357681, ENST00000391954, 
ENST00000367218, ENST00000367219, 
ENST00000341360, ENST00000466407, 
ENST00000367222, 
Fusion gene scores* DoF score8 X 4 X 6=1921 X 1 X 1=1
# samples 81
** MAII scorelog2(8/192*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(1/1*10)=3.32192809488736
Context

PubMed: ATP2B4 [Title/Abstract] AND OPTC [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneATP2B4

GO:0006874

cellular calcium ion homeostasis

19278978

HgeneATP2B4

GO:0010751

negative regulation of nitric oxide mediated signal transduction

19278978

HgeneATP2B4

GO:0033138

positive regulation of peptidyl-serine phosphorylation

19278978

HgeneATP2B4

GO:0045019

negative regulation of nitric oxide biosynthetic process

11591728|19278978

HgeneATP2B4

GO:0051001

negative regulation of nitric-oxide synthase activity

11591728|17242280|19278978|19287093

HgeneATP2B4

GO:0070885

negative regulation of calcineurin-NFAT signaling cascade

19287093

HgeneATP2B4

GO:0071872

cellular response to epinephrine stimulus

19278978

HgeneATP2B4

GO:0098736

negative regulation of the force of heart contraction

17242280

HgeneATP2B4

GO:0140199

negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

17242280

HgeneATP2B4

GO:1900082

negative regulation of arginine catabolic process

19278978

HgeneATP2B4

GO:1903249

negative regulation of citrulline biosynthetic process

19278978

HgeneATP2B4

GO:2000481

positive regulation of cAMP-dependent protein kinase activity

19278978


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVSARCTCGA-DX-AB32-01AATP2B4chr1

203683405

+OPTCchr1

203472042

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000357681ENST00000367222ATP2B4chr1

203683405

+OPTCchr1

203472042

+
In-frameENST00000391954ENST00000367222ATP2B4chr1

203683405

+OPTCchr1

203472042

+
In-frameENST00000367218ENST00000367222ATP2B4chr1

203683405

+OPTCchr1

203472042

+
In-frameENST00000367219ENST00000367222ATP2B4chr1

203683405

+OPTCchr1

203472042

+
In-frameENST00000341360ENST00000367222ATP2B4chr1

203683405

+OPTCchr1

203472042

+
intron-3CDSENST00000466407ENST00000367222ATP2B4chr1

203683405

+OPTCchr1

203472042

+

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FusionProtFeatures for ATP2B4_OPTC


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ATP2B4

P23634

OPTC

Q9UBM4

Calcium/calmodulin-regulated and magnesium-dependentenzyme that catalyzes the hydrolysis of ATP coupled with thetransport of calcium out of the cell (PubMed:8530416). Byregulating sperm cell calcium homeostasis, may play a role insperm motility (By similarity). {ECO:0000250|UniProtKB:Q6Q477,ECO:0000269|PubMed:8530416}. Binds collagen fibrils. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421114_1508021171Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421172_3568021171Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+14211_928021171Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421377_4098021171Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521114_1508021206Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521172_3568021206Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+15211_928021206Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521377_4098021206Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522114_1508021171Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522172_3568021171Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+15221_928021171Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522377_4098021171Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421114_1507901159Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421172_3567901159Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+14211_927901159Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421377_4097901159Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521114_1508021135Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521172_3568021135Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+15211_928021135Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521377_4098021135Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421151_1718021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421357_3768021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421410_4278021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+142193_1138021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521151_1718021206TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521357_3768021206TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521410_4278021206TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+152193_1138021206TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522151_1718021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522357_3768021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522410_4278021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+152293_1138021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421151_1717901159TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421357_3767901159TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421410_4277901159TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+142193_1137901159TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521151_1718021135TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521357_3768021135TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521410_4278021135TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+152193_1138021135TransmembraneHelical
TgeneOPTCchr1:203683405chr1:203472042ENST00000367222+48248_269244381RepeatNote=LRR 4
TgeneOPTCchr1:203683405chr1:203472042ENST00000367222+48270_290244381RepeatNote=LRR 5
TgeneOPTCchr1:203683405chr1:203472042ENST00000367222+48300_320244381RepeatNote=LRR 6

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+14211086_11038021171RegionCalmodulin-binding subdomain A
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+14211104_11138021171RegionCalmodulin-binding subdomain B
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+15211086_11038021206RegionCalmodulin-binding subdomain A
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+15211104_11138021206RegionCalmodulin-binding subdomain B
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+15221086_11038021171RegionCalmodulin-binding subdomain A
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+15221104_11138021171RegionCalmodulin-binding subdomain B
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+14211086_11037901159RegionCalmodulin-binding subdomain A
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+14211104_11137901159RegionCalmodulin-binding subdomain B
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+15211086_11038021135RegionCalmodulin-binding subdomain A
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+15211104_11138021135RegionCalmodulin-binding subdomain B
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+14211016_10258021171Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+14211048_12418021171Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421428_8408021171Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421861_8708021171Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421892_9118021171Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421935_9528021171Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421975_9938021171Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+15211016_10258021206Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+15211048_12418021206Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521428_8408021206Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521861_8708021206Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521892_9118021206Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521935_9528021206Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521975_9938021206Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+15221016_10258021171Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+15221048_12418021171Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522428_8408021171Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522861_8708021171Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522892_9118021171Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522935_9528021171Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522975_9938021171Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+14211016_10257901159Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+14211048_12417901159Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421428_8407901159Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421861_8707901159Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421892_9117901159Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421935_9527901159Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421975_9937901159Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+15211016_10258021135Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+15211048_12418021135Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521428_8408021135Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521861_8708021135Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521892_9118021135Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521935_9528021135Topological domainExtracellular
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521975_9938021135Topological domainCytoplasmic
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+14211026_10478021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421841_8608021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421871_8918021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421912_9348021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421953_9748021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000341360+1421994_10158021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+15211026_10478021206TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521841_8608021206TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521871_8918021206TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521912_9348021206TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521953_9748021206TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000357681+1521994_10158021206TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+15221026_10478021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522841_8608021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522871_8918021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522912_9348021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522953_9748021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367218+1522994_10158021171TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+14211026_10477901159TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421841_8607901159TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421871_8917901159TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421912_9347901159TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421953_9747901159TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000367219+1421994_10157901159TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+15211026_10478021135TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521841_8608021135TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521871_8918021135TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521912_9348021135TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521953_9748021135TransmembraneHelical
HgeneATP2B4chr1:203683405chr1:203472042ENST00000391954+1521994_10158021135TransmembraneHelical
TgeneOPTCchr1:203683405chr1:203472042ENST00000367222+48128_140244381Compositional biasNote=Cys-rich
TgeneOPTCchr1:203683405chr1:203472042ENST00000367222+4881_112244381Compositional biasNote=Ser/Thr-rich
TgeneOPTCchr1:203683405chr1:203472042ENST00000367222+48116_153244381DomainNote=LRRNT
TgeneOPTCchr1:203683405chr1:203472042ENST00000367222+48154_175244381RepeatNote=LRR 1
TgeneOPTCchr1:203683405chr1:203472042ENST00000367222+48178_199244381RepeatNote=LRR 2
TgeneOPTCchr1:203683405chr1:203472042ENST00000367222+48202_223244381RepeatNote=LRR 3


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FusionGeneSequence for ATP2B4_OPTC


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ATP2B4_ENST00000357681_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_891aa
MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKP
KTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL
QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV
VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA
VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL
DACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL
GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPM
ACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL
CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMAMEKLQFL

>In-frame_ATP2B4_ENST00000391954_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_891aa
MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKP
KTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL
QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV
VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA
VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL
DACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL
GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPM
ACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL
CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMAMEKLQFL

>In-frame_ATP2B4_ENST00000367218_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_891aa
MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKP
KTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL
QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV
VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA
VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL
DACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL
GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPM
ACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL
CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMAMEKLQFL

>In-frame_ATP2B4_ENST00000367219_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_879aa
MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKP
KTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL
QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV
VTAVGVNSQTGIILTLLGVNEDDEGEKKKKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSA
LTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAI
CSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQA
VRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAY
RDFDDTEPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIR
NEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMAMEKLQFLYLSDNLLDSIPG

>In-frame_ATP2B4_ENST00000341360_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_891aa
MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKTSPVEGLSGNPADLEKRRQVFGHNVIPPKKP
KTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL
QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVMEGSGRMV
VTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLA
VQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHL
DACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTSKILPPEKEGGLPRQVGNKTECALL
GFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPM
ACDGLRTICIAYRDFDDTEPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL
CLEGKEFNRLIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMAMEKLQFL


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ATP2B4_ENST00000357681_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_2673nt
ATGACGAACCCATCAGACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGG
AAGCTCATGGAGCTGCGTTCAAGGGATGCACTGACCCAGATTAATGTCCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACC
TCCCCTGTGGAAGGTCTGTCTGGGAACCCTGCAGATCTGGAGAAACGTAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCC
AAGACTTTCTTAGAATTAGTGTGGGAAGCTCTTCAAGATGTCACGCTTATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCC
TTTTATCGCCCTGCTGGTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTACCCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATT
GAGGGGGCAGCCATCCTTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTTTAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTG
CAGTGCCGCATTGAACAGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACTCATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGAT
ATTGCCCAAGTCAAATACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACA
GGGGAATCTGACCATGTCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTG
GTGACAGCTGTTGGTGTCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAA
GGTAAAAAACAAGGAGTCCCTGAAAATCGCAACAAAGCAAAGACCCAAGACGGAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAG
GGAATCGACAATGAGGAAAAGGACAAGAAGGCAGTCAAGGTGCCTAAAAAGGAGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCT
GTTCAGATTGGGAAAGCCGGTCTGCTCATGTCTGCTCTCACGGTTTTCATCCTGATTCTATACTTTGTGATTGACAACTTTGTGATAAAT
CGCAGACCATGGCTCCCTGAGTGTACTCCCATCTACATCCAGTACTTTGTCAAGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCT
GTGCCAGAGGGGCTGCCTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGAAGAAAATGATGAAAGACAATAACCTAGTACGGCACTTG
GATGCTTGTGAGACCATGGGCAACGCCACCGCCATCTGCTCTGATAAGACAGGCACGTTGACCATGAACCGCATGACTGTGGTACAAGCT
TATATTGGGGGCATCCATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGCCCAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATC
AACAGTGCTTATACCTCCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGCCTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTA
GGCTTTGTCACAGATCTGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGCCCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCA
GTGCGCAAGTCAATGAGCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTATGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAG
TGTAATCGAATCCTGGACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAGACAGAGATGATATGGTACGCACTGTCATCGAGCCCATG
GCCTGTGATGGACTCCGGACTATCTGCATAGCTTACCGGGACTTCGATGACACAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACC
GAACTGACCTGTATCGCGGTGGTGGGCATTGAGGACCCTGTGCGCCCAGAGGTGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATT
ACTGTCAGAATGGTGACAGGTGACAACATCAACACAGCCCGGGCCATTGCCACCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTG
TGCTTAGAAGGCAAAGAATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGGTAGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTT
CGGGTCCTGGCGCGATCTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCATAATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTG
GCTGTCACTGGTGATGGCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATGTTGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTT
TACCTGTCAGACAACCTGCTGGATTCTATCCCGGGGCCTTTGCCCCTGAGCCTGCGCTCTGTACACCTGCAGAATAACCTGATAGAGACC
ATGCAGAGAGACGTCTTCTGTGACCCCGAGGAGCACAAACACACCCGCAGGCAGCTGGAAGACATCCGCCTGGATGGCAACCCCATCAAC

>In-frame_ATP2B4_ENST00000391954_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_2673nt
ATGACGAACCCATCAGACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGG
AAGCTCATGGAGCTGCGTTCAAGGGATGCACTGACCCAGATTAATGTCCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACC
TCCCCTGTGGAAGGTCTGTCTGGGAACCCTGCAGATCTGGAGAAACGTAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCC
AAGACTTTCTTAGAATTAGTGTGGGAAGCTCTTCAAGATGTCACGCTTATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCC
TTTTATCGCCCTGCTGGTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTACCCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATT
GAGGGGGCAGCCATCCTTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTTTAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTG
CAGTGCCGCATTGAACAGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACTCATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGAT
ATTGCCCAAGTCAAATACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACA
GGGGAATCTGACCATGTCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTG
GTGACAGCTGTTGGTGTCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAA
GGTAAAAAACAAGGAGTCCCTGAAAATCGCAACAAAGCAAAGACCCAAGACGGAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAG
GGAATCGACAATGAGGAAAAGGACAAGAAGGCAGTCAAGGTGCCTAAAAAGGAGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCT
GTTCAGATTGGGAAAGCCGGTCTGCTCATGTCTGCTCTCACGGTTTTCATCCTGATTCTATACTTTGTGATTGACAACTTTGTGATAAAT
CGCAGACCATGGCTCCCTGAGTGTACTCCCATCTACATCCAGTACTTTGTCAAGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCT
GTGCCAGAGGGGCTGCCTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGAAGAAAATGATGAAAGACAATAACCTAGTACGGCACTTG
GATGCTTGTGAGACCATGGGCAACGCCACCGCCATCTGCTCTGATAAGACAGGCACGTTGACCATGAACCGCATGACTGTGGTACAAGCT
TATATTGGGGGCATCCATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGCCCAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATC
AACAGTGCTTATACCTCCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGCCTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTA
GGCTTTGTCACAGATCTGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGCCCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCA
GTGCGCAAGTCAATGAGCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTATGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAG
TGTAATCGAATCCTGGACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAGACAGAGATGATATGGTACGCACTGTCATCGAGCCCATG
GCCTGTGATGGACTCCGGACTATCTGCATAGCTTACCGGGACTTCGATGACACAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACC
GAACTGACCTGTATCGCGGTGGTGGGCATTGAGGACCCTGTGCGCCCAGAGGTGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATT
ACTGTCAGAATGGTGACAGGTGACAACATCAACACAGCCCGGGCCATTGCCACCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTG
TGCTTAGAAGGCAAAGAATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGGTAGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTT
CGGGTCCTGGCGCGATCTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCATAATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTG
GCTGTCACTGGTGATGGCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATGTTGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTT
TACCTGTCAGACAACCTGCTGGATTCTATCCCGGGGCCTTTGCCCCTGAGCCTGCGCTCTGTACACCTGCAGAATAACCTGATAGAGACC
ATGCAGAGAGACGTCTTCTGTGACCCCGAGGAGCACAAACACACCCGCAGGCAGCTGGAAGACATCCGCCTGGATGGCAACCCCATCAAC

>In-frame_ATP2B4_ENST00000367218_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_2673nt
ATGACGAACCCATCAGACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGG
AAGCTCATGGAGCTGCGTTCAAGGGATGCACTGACCCAGATTAATGTCCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACC
TCCCCTGTGGAAGGTCTGTCTGGGAACCCTGCAGATCTGGAGAAACGTAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCC
AAGACTTTCTTAGAATTAGTGTGGGAAGCTCTTCAAGATGTCACGCTTATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCC
TTTTATCGCCCTGCTGGTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTACCCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATT
GAGGGGGCAGCCATCCTTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTTTAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTG
CAGTGCCGCATTGAACAGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACTCATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGAT
ATTGCCCAAGTCAAATACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACA
GGGGAATCTGACCATGTCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTG
GTGACAGCTGTTGGTGTCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAA
GGTAAAAAACAAGGAGTCCCTGAAAATCGCAACAAAGCAAAGACCCAAGACGGAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAG
GGAATCGACAATGAGGAAAAGGACAAGAAGGCAGTCAAGGTGCCTAAAAAGGAGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCT
GTTCAGATTGGGAAAGCCGGTCTGCTCATGTCTGCTCTCACGGTTTTCATCCTGATTCTATACTTTGTGATTGACAACTTTGTGATAAAT
CGCAGACCATGGCTCCCTGAGTGTACTCCCATCTACATCCAGTACTTTGTCAAGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCT
GTGCCAGAGGGGCTGCCTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGAAGAAAATGATGAAAGACAATAACCTAGTACGGCACTTG
GATGCTTGTGAGACCATGGGCAACGCCACCGCCATCTGCTCTGATAAGACAGGCACGTTGACCATGAACCGCATGACTGTGGTACAAGCT
TATATTGGGGGCATCCATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGCCCAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATC
AACAGTGCTTATACCTCCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGCCTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTA
GGCTTTGTCACAGATCTGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGCCCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCA
GTGCGCAAGTCAATGAGCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTATGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAG
TGTAATCGAATCCTGGACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAGACAGAGATGATATGGTACGCACTGTCATCGAGCCCATG
GCCTGTGATGGACTCCGGACTATCTGCATAGCTTACCGGGACTTCGATGACACAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACC
GAACTGACCTGTATCGCGGTGGTGGGCATTGAGGACCCTGTGCGCCCAGAGGTGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATT
ACTGTCAGAATGGTGACAGGTGACAACATCAACACAGCCCGGGCCATTGCCACCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTG
TGCTTAGAAGGCAAAGAATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGGTAGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTT
CGGGTCCTGGCGCGATCTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCATAATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTG
GCTGTCACTGGTGATGGCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATGTTGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTT
TACCTGTCAGACAACCTGCTGGATTCTATCCCGGGGCCTTTGCCCCTGAGCCTGCGCTCTGTACACCTGCAGAATAACCTGATAGAGACC
ATGCAGAGAGACGTCTTCTGTGACCCCGAGGAGCACAAACACACCCGCAGGCAGCTGGAAGACATCCGCCTGGATGGCAACCCCATCAAC

>In-frame_ATP2B4_ENST00000367219_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_2637nt
ATGACGAACCCATCAGACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGG
AAGCTCATGGAGCTGCGTTCAAGGGATGCACTGACCCAGATTAATGTCCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACC
TCCCCTGTGGAAGGTCTGTCTGGGAACCCTGCAGATCTGGAGAAACGTAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCC
AAGACTTTCTTAGAATTAGTGTGGGAAGCTCTTCAAGATGTCACGCTTATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCC
TTTTATCGCCCTGCTGGTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTACCCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATT
GAGGGGGCAGCCATCCTTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTTTAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTG
CAGTGCCGCATTGAACAGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACTCATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGAT
ATTGCCCAAGTCAAATACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACA
GGGGAATCTGACCATGTCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTG
GTGACAGCTGTTGGTGTCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAA
GCAAAGACCCAAGACGGAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAGGGAATCGACAATGAGGAAAAGGACAAGAAGGCAGTC
AAGGTGCCTAAAAAGGAGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCTGTTCAGATTGGGAAAGCCGGTCTGCTCATGTCTGCT
CTCACGGTTTTCATCCTGATTCTATACTTTGTGATTGACAACTTTGTGATAAATCGCAGACCATGGCTCCCTGAGTGTACTCCCATCTAC
ATCCAGTACTTTGTCAAGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCTGTGCCAGAGGGGCTGCCTCTGGCTGTCACCATCTCA
CTGGCCTACTCTGTGAAGAAAATGATGAAAGACAATAACCTAGTACGGCACTTGGATGCTTGTGAGACCATGGGCAACGCCACCGCCATC
TGCTCTGATAAGACAGGCACGTTGACCATGAACCGCATGACTGTGGTACAAGCTTATATTGGGGGCATCCATTACCGTCAAATCCCAAGC
CCTGATGTCTTCCTGCCCAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATCAACAGTGCTTATACCTCCAAGATTCTGCCTCCAGAG
AAGGAGGGAGGCCTGCCTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTAGGCTTTGTCACAGATCTGAAGCAGGATTATCAGGCT
GTGCGTAATGAAGTGCCCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCAGTGCGCAAGTCAATGAGCACCGTCATCAGGAATCCC
AACGGTGGCTTCCGTATGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAGTGTAATCGAATCCTGGACCGGAAAGGGGAAGCAGTG
CCATTCAAGAATAAAGACAGAGATGATATGGTACGCACTGTCATCGAGCCCATGGCCTGTGATGGACTCCGGACTATCTGCATAGCTTAC
CGGGACTTCGATGACACAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACCGAACTGACCTGTATCGCGGTGGTGGGCATTGAGGAC
CCTGTGCGCCCAGAGGTGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATTACTGTCAGAATGGTGACAGGTGACAACATCAACACA
GCCCGGGCCATTGCCACCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTGTGCTTAGAAGGCAAAGAATTCAACCGGCTCATCCGC
AACGAGAAAGGCGAGGTAGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTTCGGGTCCTGGCGCGATCTTCTCCCACTGACAAGCAC
ACCCTGGTGAAAGGCATAATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTGGCTGTCACTGGTGATGGCACAAATGACGGGCCTGCT
CTGAAGAAAGCGGATGTTGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTTTACCTGTCAGACAACCTGCTGGATTCTATCCCGGGG
CCTTTGCCCCTGAGCCTGCGCTCTGTACACCTGCAGAATAACCTGATAGAGACCATGCAGAGAGACGTCTTCTGTGACCCCGAGGAGCAC
AAACACACCCGCAGGCAGCTGGAAGACATCCGCCTGGATGGCAACCCCATCAACCTCAGCCTCTTCCCCAGCGCCTACTTCTGCCTGCCT

>In-frame_ATP2B4_ENST00000341360_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_2673nt
ATGACGAACCCATCAGACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGG
AAGCTCATGGAGCTGCGTTCAAGGGATGCACTGACCCAGATTAATGTCCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACC
TCCCCTGTGGAAGGTCTGTCTGGGAACCCTGCAGATCTGGAGAAACGTAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCC
AAGACTTTCTTAGAATTAGTGTGGGAAGCTCTTCAAGATGTCACGCTTATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCC
TTTTATCGCCCTGCTGGTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTACCCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATT
GAGGGGGCAGCCATCCTTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTTTAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTG
CAGTGCCGCATTGAACAGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACTCATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGAT
ATTGCCCAAGTCAAATACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACA
GGGGAATCTGACCATGTCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTG
GTGACAGCTGTTGGTGTCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAA
GGTAAAAAACAAGGAGTCCCTGAAAATCGCAACAAAGCAAAGACCCAAGACGGAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAG
GGAATCGACAATGAGGAAAAGGACAAGAAGGCAGTCAAGGTGCCTAAAAAGGAGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCT
GTTCAGATTGGGAAAGCCGGTCTGCTCATGTCTGCTCTCACGGTTTTCATCCTGATTCTATACTTTGTGATTGACAACTTTGTGATAAAT
CGCAGACCATGGCTCCCTGAGTGTACTCCCATCTACATCCAGTACTTTGTCAAGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCT
GTGCCAGAGGGGCTGCCTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGAAGAAAATGATGAAAGACAATAACCTAGTACGGCACTTG
GATGCTTGTGAGACCATGGGCAACGCCACCGCCATCTGCTCTGATAAGACAGGCACGTTGACCATGAACCGCATGACTGTGGTACAAGCT
TATATTGGGGGCATCCATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGCCCAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATC
AACAGTGCTTATACCTCCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGCCTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTA
GGCTTTGTCACAGATCTGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGCCCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCA
GTGCGCAAGTCAATGAGCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTATGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAG
TGTAATCGAATCCTGGACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAGACAGAGATGATATGGTACGCACTGTCATCGAGCCCATG
GCCTGTGATGGACTCCGGACTATCTGCATAGCTTACCGGGACTTCGATGACACAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACC
GAACTGACCTGTATCGCGGTGGTGGGCATTGAGGACCCTGTGCGCCCAGAGGTGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATT
ACTGTCAGAATGGTGACAGGTGACAACATCAACACAGCCCGGGCCATTGCCACCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTG
TGCTTAGAAGGCAAAGAATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGGTAGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTT
CGGGTCCTGGCGCGATCTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCATAATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTG
GCTGTCACTGGTGATGGCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATGTTGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTT
TACCTGTCAGACAACCTGCTGGATTCTATCCCGGGGCCTTTGCCCCTGAGCCTGCGCTCTGTACACCTGCAGAATAACCTGATAGAGACC
ATGCAGAGAGACGTCTTCTGTGACCCCGAGGAGCACAAACACACCCGCAGGCAGCTGGAAGACATCCGCCTGGATGGCAACCCCATCAAC


* Fusion transcript sequences (Full-length transcript).
>In-frame_ATP2B4_ENST00000357681_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_4040nt
CACCCTCACCCCTCCTCCACCCCTACTCAGCTTTCTATTCAACAAGTGAGAGCAAGGGCGGGGAAGAAAGCCGACAGGGGAGAGGATTGC
TTCCCTTTCTTTTCCCATTCCCCCTTAAGACGAACCAGGAAGTAACCGCAAGAATCGGGCCACCTTAACAGTAGAGTAATGGTTTGGCCT
CGCGCCAAGTCCCACCTCTGTTCCAGCTCCTGCTCCTCCCCTCTCTCTTCCCGCACTGCTTGGGGAGAGCTGGTGAGCAAGAGTCTGGCC
CGAGTTAGCTAGAGCTGTTGCCATGACAAGCATTTTCTTAAGAAAGCTCTGCTGTTGAGATCGTCCAAAGCTGGGGGCTGGGAGGGGGGG
CACGAACTTCGTGGGGCACCATCCCTCCGAAGAGAGCAAGATCAGAGACACCCGCCCAGCTCTCCTGCACCCTTTTTCTTTCAGGAACCT
GAGAGGTCCTTCCCATTGGAGGGGCAGGGGGAGGAGACCCAGCCCACTCCCCGGCCTTAGCCAGAAAGGCAAGAGAGCAAAGCCAGCGTC
TCTAGCTTGGTTGCCACACTGGGGAGACTGGTGGGTGGTCACCCCACCCTACCCTCATCCATGGAAACCCGGAGGGAGAGTCCCGCCTGA
AGAAACCTGGATCTTTGCTAGAAAGAGAGAGATCCAGTTGTCATCGGTATCCAGGAAGCTCTCCTCTTCCTCCTCCTGACGTCTACTACT
ACAGTTGCTGGTTGTTGCTAAGGTTGCTGCCATGGTAACATGCACATCCTGTTTACACCTTCATCTGGGCAAGTTGGTCTAAGCTAGGAA
CCTACCTACCCTGGACAACTACTATCATCACCACCTGGGGACACCAATCATCGTGACACGGAGTCCACCTTCCACTCAGTTCCCCCATCC
TCTTCCTCCTCTCGCTGCCAGACTTCATACGGAAGAAAGGATCTAGACTTCGGACGGCTACTCGGGAGCTTATTGCACAAGATATATTCA
ATCTATTCCCTCACTGGGCCCCCAGAGAAGCAAGAAGTAGGAAGAAGTTGAGACAGGGAGGCAGGAGACACTGGTCAGTTGAAGGGAAAC
GCTACATCTTCTCTGGTTGAGGGGCTTGGTAACAGCAGGCAAAATGACGAACCCATCAGACCGTGTCTTGCCTGCCAACTCGATGGCCGA
GAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGGAAGCTCATGGAGCTGCGTTCAAGGGATGCACTGACCCAGATTAATGT
CCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACCTCCCCTGTGGAAGGTCTGTCTGGGAACCCTGCAGATCTGGAGAAACG
TAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCCAAGACTTTCTTAGAATTAGTGTGGGAAGCTCTTCAAGATGTCACGCT
TATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCCTTTTATCGCCCTGCTGGTGAAGAAAATGAACTGTGTGGTCAAGTCGC
AACTACCCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATTGAGGGGGCAGCCATCCTTTTCTCAGTGATCATCGTGGTGTTAGTGAC
TGCCTTTAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTGCAGTGCCGCATTGAACAGGAGCAAAAGTTCTCCATCATCCGAAACGG
TCAACTCATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGATATTGCCCAAGTCAAATACGGTGATCTGCTGCCTGCAGATGGAATCCT
GATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACAGGGGAATCTGACCATGTCAAGAAGTCCCTGGACAAAGACCCCATGTT
GCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTGGTGACAGCTGTTGGTGTCAACTCTCAGACTGGAATCATCCTTACTCT
CTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAAGGTAAAAAACAAGGAGTCCCTGAAAATCGCAACAAAGCAAAGACCCA
AGACGGAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAGGGAATCGACAATGAGGAAAAGGACAAGAAGGCAGTCAAGGTGCCTAA
AAAGGAGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCTGTTCAGATTGGGAAAGCCGGTCTGCTCATGTCTGCTCTCACGGTTTT
CATCCTGATTCTATACTTTGTGATTGACAACTTTGTGATAAATCGCAGACCATGGCTCCCTGAGTGTACTCCCATCTACATCCAGTACTT
TGTCAAGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCTGTGCCAGAGGGGCTGCCTCTGGCTGTCACCATCTCACTGGCCTACTC
TGTGAAGAAAATGATGAAAGACAATAACCTAGTACGGCACTTGGATGCTTGTGAGACCATGGGCAACGCCACCGCCATCTGCTCTGATAA
GACAGGCACGTTGACCATGAACCGCATGACTGTGGTACAAGCTTATATTGGGGGCATCCATTACCGTCAAATCCCAAGCCCTGATGTCTT
CCTGCCCAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATCAACAGTGCTTATACCTCCAAGATTCTGCCTCCAGAGAAGGAGGGAGG
CCTGCCTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTAGGCTTTGTCACAGATCTGAAGCAGGATTATCAGGCTGTGCGTAATGA
AGTGCCCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCAGTGCGCAAGTCAATGAGCACCGTCATCAGGAATCCCAACGGTGGCTT
CCGTATGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAGTGTAATCGAATCCTGGACCGGAAAGGGGAAGCAGTGCCATTCAAGAA
TAAAGACAGAGATGATATGGTACGCACTGTCATCGAGCCCATGGCCTGTGATGGACTCCGGACTATCTGCATAGCTTACCGGGACTTCGA
TGACACAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACCGAACTGACCTGTATCGCGGTGGTGGGCATTGAGGACCCTGTGCGCCC
AGAGGTGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATTACTGTCAGAATGGTGACAGGTGACAACATCAACACAGCCCGGGCCAT
TGCCACCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTGTGCTTAGAAGGCAAAGAATTCAACCGGCTCATCCGCAACGAGAAAGG
CGAGGTAGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTTCGGGTCCTGGCGCGATCTTCTCCCACTGACAAGCACACCCTGGTGAA
AGGCATAATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTGGCTGTCACTGGTGATGGCACAAATGACGGGCCTGCTCTGAAGAAAGC
GGATGTTGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTTTACCTGTCAGACAACCTGCTGGATTCTATCCCGGGGCCTTTGCCCCT
GAGCCTGCGCTCTGTACACCTGCAGAATAACCTGATAGAGACCATGCAGAGAGACGTCTTCTGTGACCCCGAGGAGCACAAACACACCCG
CAGGCAGCTGGAAGACATCCGCCTGGATGGCAACCCCATCAACCTCAGCCTCTTCCCCAGCGCCTACTTCTGCCTGCCTCGGCTCCCCAT
CGGCCGCTTCACGTAGCTCGGAGCCCTTCCACTCCTCCCAGGTCATCTCTTGGACCAGCGGGCATCACATTCTCCAGCAGCCGCCATCTC
ACACGCCTCCCTCCTGTGGCCGCCGGCAGCATGGACAAAGGTCTCCATGCAGGGGGAGGAGGCCTGCTTCTTTCCCCACAGCTCTCACGT

>In-frame_ATP2B4_ENST00000391954_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_3801nt
TTGGGGAGAGCTGGTGAGCAAGAGTCTGGCCCGAGTTAGCTAGAGCTGTTGCCATGACAAGCATTTTCTTAAGAAAGCTCTGCTGTTGAG
ATCGTCCAAAGCTGGGGGCTGGGAGGGGGGGCACGAACTTCGTGGGGCACCATCCCTCCGAAGAGAGCAAGATCAGAGACACCCGCCCAG
CTCTCCTGCACCCTTTTTCTTTCAGGAACCTGAGAGGTCCTTCCCATTGGAGGGGCAGGGGGAGGAGACCCAGCCCACTCCCCGGCCTTA
GCCAGAAAGGCAAGAGAGCAAAGCCAGCGTCTCTAGCTTGGTTGCCACACTGGGGAGACTGGTGGGTGGTCACCCCACCCTACCCTCATC
CATGGAAACCCGGAGGGAGAGTCCCGCCTGAAGAAACCTGGATCTTTGCTAGAAAGAGAGAGATCCAGTTGTCATCGGTATCCAGGAAGC
TCTCCTCTTCCTCCTCCTGACGTCTACTACTACAGTTGCTGGTTGTTGCTAAGGTTGCTGCCATGGTAACATGCACATCCTGTTTACACC
TTCATCTGGGCAAGTTGGTCTAAGCTAGGAACCTACCTACCCTGGACAACTACTATCATCACCACCTGGGGACACCAATCATCGTGACAC
GGAGTCCACCTTCCACTCAGTTCCCCCATCCTCTTCCTCCTCTCGCTGCCAGACTTCATACGGAAGAAAGGATCTAGACTTCGGACGGCT
ACTCGGGAGCTTATTGCACAAGATATATTCAATCTATTCCCTCACTGGGCCCCCAGAGAAGCAAGAAGTAGGAAGAAGTTGAGACAGGGA
GGCAGGAGACACTGGTCAGTTGAAGGGAAACGCTACATCTTCTCTGGTTGAGGGGCTTGGTAACAGCAGGCAAAATGACGAACCCATCAG
ACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGGAAGCTCATGGAGCTGC
GTTCAAGGGATGCACTGACCCAGATTAATGTCCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACCTCCCCTGTGGAAGGTC
TGTCTGGGAACCCTGCAGATCTGGAGAAACGTAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCCAAGACTTTCTTAGAAT
TAGTGTGGGAAGCTCTTCAAGATGTCACGCTTATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCCTTTTATCGCCCTGCTG
GTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTACCCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATTGAGGGGGCAGCCATCC
TTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTTTAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTGCAGTGCCGCATTGAAC
AGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACTCATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGATATTGCCCAAGTCAAAT
ACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACAGGGGAATCTGACCATG
TCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTGGTGACAGCTGTTGGTG
TCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAAGGTAAAAAACAAGGAG
TCCCTGAAAATCGCAACAAAGCAAAGACCCAAGACGGAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAGGGAATCGACAATGAGG
AAAAGGACAAGAAGGCAGTCAAGGTGCCTAAAAAGGAGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCTGTTCAGATTGGGAAAG
CCGGTCTGCTCATGTCTGCTCTCACGGTTTTCATCCTGATTCTATACTTTGTGATTGACAACTTTGTGATAAATCGCAGACCATGGCTCC
CTGAGTGTACTCCCATCTACATCCAGTACTTTGTCAAGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCTGTGCCAGAGGGGCTGC
CTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGAAGAAAATGATGAAAGACAATAACCTAGTACGGCACTTGGATGCTTGTGAGACCA
TGGGCAACGCCACCGCCATCTGCTCTGATAAGACAGGCACGTTGACCATGAACCGCATGACTGTGGTACAAGCTTATATTGGGGGCATCC
ATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGCCCAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATCAACAGTGCTTATACCT
CCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGCCTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTAGGCTTTGTCACAGATC
TGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGCCCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCAGTGCGCAAGTCAATGA
GCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTATGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAGTGTAATCGAATCCTGG
ACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAGACAGAGATGATATGGTACGCACTGTCATCGAGCCCATGGCCTGTGATGGACTCC
GGACTATCTGCATAGCTTACCGGGACTTCGATGACACAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACCGAACTGACCTGTATCG
CGGTGGTGGGCATTGAGGACCCTGTGCGCCCAGAGGTGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATTACTGTCAGAATGGTGA
CAGGTGACAACATCAACACAGCCCGGGCCATTGCCACCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTGTGCTTAGAAGGCAAAG
AATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGGTAGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTTCGGGTCCTGGCGCGAT
CTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCATAATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTGGCTGTCACTGGTGATG
GCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATGTTGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTTTACCTGTCAGACAACC
TGCTGGATTCTATCCCGGGGCCTTTGCCCCTGAGCCTGCGCTCTGTACACCTGCAGAATAACCTGATAGAGACCATGCAGAGAGACGTCT
TCTGTGACCCCGAGGAGCACAAACACACCCGCAGGCAGCTGGAAGACATCCGCCTGGATGGCAACCCCATCAACCTCAGCCTCTTCCCCA
GCGCCTACTTCTGCCTGCCTCGGCTCCCCATCGGCCGCTTCACGTAGCTCGGAGCCCTTCCACTCCTCCCAGGTCATCTCTTGGACCAGC
GGGCATCACATTCTCCAGCAGCCGCCATCTCACACGCCTCCCTCCTGTGGCCGCCGGCAGCATGGACAAAGGTCTCCATGCAGGGGGAGG
AGGCCTGCTTCTTTCCCCACAGCTCTCACGTCTCCCTTCTCCCTGCGGGTGACAAAGAAGCCCAAGGACCACCTCCTTCCTGCCTCATTG

>In-frame_ATP2B4_ENST00000367218_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_3801nt
TTGGGGAGAGCTGGTGAGCAAGAGTCTGGCCCGAGTTAGCTAGAGCTGTTGCCATGACAAGCATTTTCTTAAGAAAGCTCTGCTGTTGAG
ATCGTCCAAAGCTGGGGGCTGGGAGGGGGGGCACGAACTTCGTGGGGCACCATCCCTCCGAAGAGAGCAAGATCAGAGACACCCGCCCAG
CTCTCCTGCACCCTTTTTCTTTCAGGAACCTGAGAGGTCCTTCCCATTGGAGGGGCAGGGGGAGGAGACCCAGCCCACTCCCCGGCCTTA
GCCAGAAAGGCAAGAGAGCAAAGCCAGCGTCTCTAGCTTGGTTGCCACACTGGGGAGACTGGTGGGTGGTCACCCCACCCTACCCTCATC
CATGGAAACCCGGAGGGAGAGTCCCGCCTGAAGAAACCTGGATCTTTGCTAGAAAGAGAGAGATCCAGTTGTCATCGGTATCCAGGAAGC
TCTCCTCTTCCTCCTCCTGACGTCTACTACTACAGTTGCTGGTTGTTGCTAAGGTTGCTGCCATGGTAACATGCACATCCTGTTTACACC
TTCATCTGGGCAAGTTGGTCTAAGCTAGGAACCTACCTACCCTGGACAACTACTATCATCACCACCTGGGGACACCAATCATCGTGACAC
GGAGTCCACCTTCCACTCAGTTCCCCCATCCTCTTCCTCCTCTCGCTGCCAGACTTCATACGGAAGAAAGGATCTAGACTTCGGACGGCT
ACTCGGGAGCTTATTGCACAAGATATATTCAATCTATTCCCTCACTGGGCCCCCAGAGAAGCAAGAAGTAGGAAGAAGTTGAGACAGGGA
GGCAGGAGACACTGGTCAGTTGAAGGGAAACGCTACATCTTCTCTGGTTGAGGGGCTTGGTAACAGCAGGCAAAATGACGAACCCATCAG
ACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGGAAGCTCATGGAGCTGC
GTTCAAGGGATGCACTGACCCAGATTAATGTCCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACCTCCCCTGTGGAAGGTC
TGTCTGGGAACCCTGCAGATCTGGAGAAACGTAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCCAAGACTTTCTTAGAAT
TAGTGTGGGAAGCTCTTCAAGATGTCACGCTTATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCCTTTTATCGCCCTGCTG
GTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTACCCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATTGAGGGGGCAGCCATCC
TTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTTTAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTGCAGTGCCGCATTGAAC
AGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACTCATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGATATTGCCCAAGTCAAAT
ACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACAGGGGAATCTGACCATG
TCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTGGTGACAGCTGTTGGTG
TCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAAGGTAAAAAACAAGGAG
TCCCTGAAAATCGCAACAAAGCAAAGACCCAAGACGGAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAGGGAATCGACAATGAGG
AAAAGGACAAGAAGGCAGTCAAGGTGCCTAAAAAGGAGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCTGTTCAGATTGGGAAAG
CCGGTCTGCTCATGTCTGCTCTCACGGTTTTCATCCTGATTCTATACTTTGTGATTGACAACTTTGTGATAAATCGCAGACCATGGCTCC
CTGAGTGTACTCCCATCTACATCCAGTACTTTGTCAAGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCTGTGCCAGAGGGGCTGC
CTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGAAGAAAATGATGAAAGACAATAACCTAGTACGGCACTTGGATGCTTGTGAGACCA
TGGGCAACGCCACCGCCATCTGCTCTGATAAGACAGGCACGTTGACCATGAACCGCATGACTGTGGTACAAGCTTATATTGGGGGCATCC
ATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGCCCAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATCAACAGTGCTTATACCT
CCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGCCTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTAGGCTTTGTCACAGATC
TGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGCCCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCAGTGCGCAAGTCAATGA
GCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTATGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAGTGTAATCGAATCCTGG
ACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAGACAGAGATGATATGGTACGCACTGTCATCGAGCCCATGGCCTGTGATGGACTCC
GGACTATCTGCATAGCTTACCGGGACTTCGATGACACAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACCGAACTGACCTGTATCG
CGGTGGTGGGCATTGAGGACCCTGTGCGCCCAGAGGTGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATTACTGTCAGAATGGTGA
CAGGTGACAACATCAACACAGCCCGGGCCATTGCCACCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTGTGCTTAGAAGGCAAAG
AATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGGTAGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTTCGGGTCCTGGCGCGAT
CTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCATAATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTGGCTGTCACTGGTGATG
GCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATGTTGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTTTACCTGTCAGACAACC
TGCTGGATTCTATCCCGGGGCCTTTGCCCCTGAGCCTGCGCTCTGTACACCTGCAGAATAACCTGATAGAGACCATGCAGAGAGACGTCT
TCTGTGACCCCGAGGAGCACAAACACACCCGCAGGCAGCTGGAAGACATCCGCCTGGATGGCAACCCCATCAACCTCAGCCTCTTCCCCA
GCGCCTACTTCTGCCTGCCTCGGCTCCCCATCGGCCGCTTCACGTAGCTCGGAGCCCTTCCACTCCTCCCAGGTCATCTCTTGGACCAGC
GGGCATCACATTCTCCAGCAGCCGCCATCTCACACGCCTCCCTCCTGTGGCCGCCGGCAGCATGGACAAAGGTCTCCATGCAGGGGGAGG
AGGCCTGCTTCTTTCCCCACAGCTCTCACGTCTCCCTTCTCCCTGCGGGTGACAAAGAAGCCCAAGGACCACCTCCTTCCTGCCTCATTG

>In-frame_ATP2B4_ENST00000367219_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_3765nt
TTGGGGAGAGCTGGTGAGCAAGAGTCTGGCCCGAGTTAGCTAGAGCTGTTGCCATGACAAGCATTTTCTTAAGAAAGCTCTGCTGTTGAG
ATCGTCCAAAGCTGGGGGCTGGGAGGGGGGGCACGAACTTCGTGGGGCACCATCCCTCCGAAGAGAGCAAGATCAGAGACACCCGCCCAG
CTCTCCTGCACCCTTTTTCTTTCAGGAACCTGAGAGGTCCTTCCCATTGGAGGGGCAGGGGGAGGAGACCCAGCCCACTCCCCGGCCTTA
GCCAGAAAGGCAAGAGAGCAAAGCCAGCGTCTCTAGCTTGGTTGCCACACTGGGGAGACTGGTGGGTGGTCACCCCACCCTACCCTCATC
CATGGAAACCCGGAGGGAGAGTCCCGCCTGAAGAAACCTGGATCTTTGCTAGAAAGAGAGAGATCCAGTTGTCATCGGTATCCAGGAAGC
TCTCCTCTTCCTCCTCCTGACGTCTACTACTACAGTTGCTGGTTGTTGCTAAGGTTGCTGCCATGGTAACATGCACATCCTGTTTACACC
TTCATCTGGGCAAGTTGGTCTAAGCTAGGAACCTACCTACCCTGGACAACTACTATCATCACCACCTGGGGACACCAATCATCGTGACAC
GGAGTCCACCTTCCACTCAGTTCCCCCATCCTCTTCCTCCTCTCGCTGCCAGACTTCATACGGAAGAAAGGATCTAGACTTCGGACGGCT
ACTCGGGAGCTTATTGCACAAGATATATTCAATCTATTCCCTCACTGGGCCCCCAGAGAAGCAAGAAGTAGGAAGAAGTTGAGACAGGGA
GGCAGGAGACACTGGTCAGTTGAAGGGAAACGCTACATCTTCTCTGGTTGAGGGGCTTGGTAACAGCAGGCAAAATGACGAACCCATCAG
ACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCGTGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGGAAGCTCATGGAGCTGC
GTTCAAGGGATGCACTGACCCAGATTAATGTCCACTATGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACCTCCCCTGTGGAAGGTC
TGTCTGGGAACCCTGCAGATCTGGAGAAACGTAGGCAGGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCCAAGACTTTCTTAGAAT
TAGTGTGGGAAGCTCTTCAAGATGTCACGCTTATCATCCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCCTTTTATCGCCCTGCTG
GTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTACCCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATTGAGGGGGCAGCCATCC
TTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTTTAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTGCAGTGCCGCATTGAAC
AGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACTCATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGATATTGCCCAAGTCAAAT
ACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCAAGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACAGGGGAATCTGACCATG
TCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTCAGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTGGTGACAGCTGTTGGTG
TCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGGGGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAAGCAAAGACCCAAGACG
GAGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAGGGAATCGACAATGAGGAAAAGGACAAGAAGGCAGTCAAGGTGCCTAAAAAGG
AGAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCTGTTCAGATTGGGAAAGCCGGTCTGCTCATGTCTGCTCTCACGGTTTTCATCC
TGATTCTATACTTTGTGATTGACAACTTTGTGATAAATCGCAGACCATGGCTCCCTGAGTGTACTCCCATCTACATCCAGTACTTTGTCA
AGTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCTGTGCCAGAGGGGCTGCCTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGA
AGAAAATGATGAAAGACAATAACCTAGTACGGCACTTGGATGCTTGTGAGACCATGGGCAACGCCACCGCCATCTGCTCTGATAAGACAG
GCACGTTGACCATGAACCGCATGACTGTGGTACAAGCTTATATTGGGGGCATCCATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGC
CCAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATCAACAGTGCTTATACCTCCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGC
CTCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTAGGCTTTGTCACAGATCTGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGC
CCGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCAGTGCGCAAGTCAATGAGCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTA
TGTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAGTGTAATCGAATCCTGGACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAG
ACAGAGATGATATGGTACGCACTGTCATCGAGCCCATGGCCTGTGATGGACTCCGGACTATCTGCATAGCTTACCGGGACTTCGATGACA
CAGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACCGAACTGACCTGTATCGCGGTGGTGGGCATTGAGGACCCTGTGCGCCCAGAGG
TGCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATTACTGTCAGAATGGTGACAGGTGACAACATCAACACAGCCCGGGCCATTGCCA
CCAAATGTGGCATTCTGACACCTGGGGATGACTTCCTGTGCTTAGAAGGCAAAGAATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGG
TAGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTTCGGGTCCTGGCGCGATCTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCA
TAATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTGGCTGTCACTGGTGATGGCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATG
TTGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTTTACCTGTCAGACAACCTGCTGGATTCTATCCCGGGGCCTTTGCCCCTGAGCC
TGCGCTCTGTACACCTGCAGAATAACCTGATAGAGACCATGCAGAGAGACGTCTTCTGTGACCCCGAGGAGCACAAACACACCCGCAGGC
AGCTGGAAGACATCCGCCTGGATGGCAACCCCATCAACCTCAGCCTCTTCCCCAGCGCCTACTTCTGCCTGCCTCGGCTCCCCATCGGCC
GCTTCACGTAGCTCGGAGCCCTTCCACTCCTCCCAGGTCATCTCTTGGACCAGCGGGCATCACATTCTCCAGCAGCCGCCATCTCACACG
CCTCCCTCCTGTGGCCGCCGGCAGCATGGACAAAGGTCTCCATGCAGGGGGAGGAGGCCTGCTTCTTTCCCCACAGCTCTCACGTCTCCC

>In-frame_ATP2B4_ENST00000341360_chr1_203683405_+_OPTC_ENST00000367222_chr1_203472042_+_3314nt
GCTGGTTGTTGCTAAGGTTGCTGCCATGGTAACATGCACATCCTGTTTACACCTTCATCTGGGCAAGTTGGTCTAAGCTAGGAACCTACC
TACCCTGGACAACTACTATCATCACCACCTGGGGACACCAATCATCGTGACACGGAGTCCACCTTCCACTCAGTTCCCCCATCCTCTTCC
TCCTCTCGCTGCCAGACTTCATACGGAAGAAAGGATCTAGACTTCGGACGGCTACTCGGGAGCTTATTGCACAAGATATATTCAATCTAT
TCCCTCACTGGGCCCCCAGAGAAGCAAGAAGTAGGAAGAAGTTGAGACAGGGAGGCAGGAGACACTGGTCAGTTGAAGGGAAACGCTACA
TCTTCTCTGGTTGAGGGGCTTGGTAACAGCAGGCAAAATGACGAACCCATCAGACCGTGTCTTGCCTGCCAACTCGATGGCCGAGAGCCG
TGAAGGGGACTTTGGCTGCACAGTAATGGAACTGAGGAAGCTCATGGAGCTGCGTTCAAGGGATGCACTGACCCAGATTAATGTCCACTA
TGGAGGTGTACAGAATCTCTGCAGTAGACTGAAAACCTCCCCTGTGGAAGGTCTGTCTGGGAACCCTGCAGATCTGGAGAAACGTAGGCA
GGTGTTTGGACACAACGTGATCCCCCCCAAAAAGCCCAAGACTTTCTTAGAATTAGTGTGGGAAGCTCTTCAAGATGTCACGCTTATCAT
CCTGGAGATTGCAGCCATCATCTCCCTGGTCCTGTCCTTTTATCGCCCTGCTGGTGAAGAAAATGAACTGTGTGGTCAAGTCGCAACTAC
CCCAGAAGATGAAAATGAGGCACAAGCTGGCTGGATTGAGGGGGCAGCCATCCTTTTCTCAGTGATCATCGTGGTGTTAGTGACTGCCTT
TAATGATTGGAGCAAAGAGAAGCAATTCCGGGGGCTGCAGTGCCGCATTGAACAGGAGCAAAAGTTCTCCATCATCCGAAACGGTCAACT
CATCCAGCTCCCTGTGGCTGAGATTGTGGTTGGTGATATTGCCCAAGTCAAATACGGTGATCTGCTGCCTGCAGATGGAATCCTGATCCA
AGGGAATGATCTGAAGATTGATGAGAGCTCTCTGACAGGGGAATCTGACCATGTCAAGAAGTCCCTGGACAAAGACCCCATGTTGCTCTC
AGGGACCCATGTCATGGAAGGTTCTGGCCGGATGGTGGTGACAGCTGTTGGTGTCAACTCTCAGACTGGAATCATCCTTACTCTCTTGGG
GGTCAATGAGGATGACGAAGGGGAGAAAAAGAAGAAAGGTAAAAAACAAGGAGTCCCTGAAAATCGCAACAAAGCAAAGACCCAAGACGG
AGTGGCCCTGGAAATCCAGCCACTCAACAGCCAGGAGGGAATCGACAATGAGGAAAAGGACAAGAAGGCAGTCAAGGTGCCTAAAAAGGA
GAAGTCAGTGCTGCAGGGCAAGCTGACTCGCCTGGCTGTTCAGATTGGGAAAGCCGGTCTGCTCATGTCTGCTCTCACGGTTTTCATCCT
GATTCTATACTTTGTGATTGACAACTTTGTGATAAATCGCAGACCATGGCTCCCTGAGTGTACTCCCATCTACATCCAGTACTTTGTCAA
GTTCTTCATCATCGGCATCACTGTACTGGTGGTGGCTGTGCCAGAGGGGCTGCCTCTGGCTGTCACCATCTCACTGGCCTACTCTGTGAA
GAAAATGATGAAAGACAATAACCTAGTACGGCACTTGGATGCTTGTGAGACCATGGGCAACGCCACCGCCATCTGCTCTGATAAGACAGG
CACGTTGACCATGAACCGCATGACTGTGGTACAAGCTTATATTGGGGGCATCCATTACCGTCAAATCCCAAGCCCTGATGTCTTCCTGCC
CAAAGTCCTGGACCTCATTGTCAATGGCATTTCTATCAACAGTGCTTATACCTCCAAGATTCTGCCTCCAGAGAAGGAGGGAGGCCTGCC
TCGGCAGGTGGGCAACAAGACCGAGTGTGCTCTGCTAGGCTTTGTCACAGATCTGAAGCAGGATTATCAGGCTGTGCGTAATGAAGTGCC
CGAGGAGAAGCTCTACAAGGTGTACACCTTTAACTCAGTGCGCAAGTCAATGAGCACCGTCATCAGGAATCCCAACGGTGGCTTCCGTAT
GTACAGCAAGGGCGCCTCTGAGATCATCTTGCGCAAGTGTAATCGAATCCTGGACCGGAAAGGGGAAGCAGTGCCATTCAAGAATAAAGA
CAGAGATGATATGGTACGCACTGTCATCGAGCCCATGGCCTGTGATGGACTCCGGACTATCTGCATAGCTTACCGGGACTTCGATGACAC
AGAGCCCTCTTGGGACAATGAGAATGAGATCCTCACCGAACTGACCTGTATCGCGGTGGTGGGCATTGAGGACCCTGTGCGCCCAGAGGT
GCCAGATGCTATTGCCAAATGCAAACAAGCTGGCATTACTGTCAGAATGGTGACAGGTGACAACATCAACACAGCCCGGGCCATTGCCAC
CAAATGTGGCATTCTGACACCTGGGGATGACTTCCTGTGCTTAGAAGGCAAAGAATTCAACCGGCTCATCCGCAACGAGAAAGGCGAGGT
AGAGCAAGAAAAGCTGGACAAGATCTGGCCTAAGCTTCGGGTCCTGGCGCGATCTTCTCCCACTGACAAGCACACCCTGGTGAAAGGCAT
AATTGACAGCACTGTTGGGGAACACCGGCAGGTCGTGGCTGTCACTGGTGATGGCACAAATGACGGGCCTGCTCTGAAGAAAGCGGATGT
TGGTTTTGCCATGGCAATGGAGAAGCTGCAGTTCCTTTACCTGTCAGACAACCTGCTGGATTCTATCCCGGGGCCTTTGCCCCTGAGCCT
GCGCTCTGTACACCTGCAGAATAACCTGATAGAGACCATGCAGAGAGACGTCTTCTGTGACCCCGAGGAGCACAAACACACCCGCAGGCA
GCTGGAAGACATCCGCCTGGATGGCAACCCCATCAACCTCAGCCTCTTCCCCAGCGCCTACTTCTGCCTGCCTCGGCTCCCCATCGGCCG
CTTCACGTAGCTCGGAGCCCTTCCACTCCTCCCAGGTCATCTCTTGGACCAGCGGGCATCACATTCTCCAGCAGCCGCCATCTCACACGC
CTCCCTCCTGTGGCCGCCGGCAGCATGGACAAAGGTCTCCATGCAGGGGGAGGAGGCCTGCTTCTTTCCCCACAGCTCTCACGTCTCCCT


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FusionGenePPI for ATP2B4_OPTC


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ATP2B4DLG1, CASK, DLG2, DLG3, ERBB2IP, ADRB2, CDK7, LGALS3, BSG, LGALS8, TAS2R7, EDA2R, HSD17B6, LGALS9, AGTR1, LGALS9C, SLC39A4, LYPD3, DLK1, WBP1, PTGER3, TMEM52B, ATP1A1, ATP9A, HM13, ATP5J, CANX, CLGN, TMEM17, EGFR, CDH1, CTDSPL, ATP2B2, TMEM5, LPAR1, LILRB4, FPR2, IPPK, FAM174A, C3AR1, GPC1, CYP2B6, PCDHGB1, APLNR, KCNA5, NMUR2, HTR3A, VAC14, TRIM25OPTC


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for ATP2B4_OPTC


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for ATP2B4_OPTC


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource