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Fusion gene ID: 33293 |
FusionGeneSummary for SERPINA3_CPB1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SERPINA3_CPB1 | Fusion gene ID: 33293 | Hgene | Tgene | Gene symbol | SERPINA3 | CPB1 | Gene ID | 12 | 1360 |
| Gene name | serpin family A member 3 | carboxypeptidase B1 | |
| Synonyms | AACT|ACT|GIG24|GIG25 | CPB|PASP|PCPB | |
| Cytomap | 14q32.13 | 3q24 | |
| Type of gene | protein-coding | protein-coding | |
| Description | alpha-1-antichymotrypsincell growth-inhibiting gene 24/25 proteingrowth-inhibiting protein 24growth-inhibiting protein 25serine (or cysteine) proteinase inhibitor, clade A, member 3serpin A3serpin peptidase inhibitor, clade A (alpha-1 antiproteinase | carboxypeptidase Bcarboxypeptidase B1 (tissue)pancreas-specific proteinpancreatic carboxypeptidase Bprocarboxypeptidase Bprotaminasetissue carboxypeptidase B | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P01011 | P15086 | |
| Ensembl transtripts involved in fusion gene | ENST00000393078, ENST00000485588, ENST00000393080, ENST00000467132, ENST00000482740, | ENST00000491148, ENST00000282957, ENST00000498639, | |
| Fusion gene scores | * DoF score | 6 X 8 X 4=192 | 21 X 24 X 3=1512 |
| # samples | 10 | 19 | |
| ** MAII score | log2(10/192*10)=-0.941106310946431 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(19/1512*10)=-2.99238681589013 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: SERPINA3 [Title/Abstract] AND CPB1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-B6-A0RP-01A | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000393078 | ENST00000491148 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| In-frame | ENST00000393078 | ENST00000282957 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| 5CDS-intron | ENST00000393078 | ENST00000498639 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| intron-3CDS | ENST00000485588 | ENST00000491148 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| intron-3CDS | ENST00000485588 | ENST00000282957 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| intron-intron | ENST00000485588 | ENST00000498639 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| In-frame | ENST00000393080 | ENST00000491148 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| In-frame | ENST00000393080 | ENST00000282957 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| 5CDS-intron | ENST00000393080 | ENST00000498639 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| In-frame | ENST00000467132 | ENST00000491148 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| In-frame | ENST00000467132 | ENST00000282957 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| 5CDS-intron | ENST00000467132 | ENST00000498639 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| intron-3CDS | ENST00000482740 | ENST00000491148 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| intron-3CDS | ENST00000482740 | ENST00000282957 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
| intron-intron | ENST00000482740 | ENST00000498639 | SERPINA3 | chr14 | 95081421 | + | CPB1 | chr3 | 148563211 | + |
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FusionProtFeatures for SERPINA3_CPB1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SERPINA3 | CPB1 |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >CPB1 | chr14:95081421 | chr3:148563211 | ENST00000282957 | + | 7 | 11 | 305_306 | 259 | 418 | Region | Substrate binding |
| Tgene | >CPB1 | chr14:95081421 | chr3:148563211 | ENST00000491148 | + | 8 | 12 | 305_306 | 259 | 418 | Region | Substrate binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >SERPINA3 | chr14:95081421 | chr3:148563211 | ENST00000393078 | + | 2 | 5 | 235_237 | 214 | 424 | DNA binding | . |
| Hgene | >SERPINA3 | chr14:95081421 | chr3:148563211 | ENST00000393080 | + | 2 | 5 | 235_237 | 214 | 424 | DNA binding | . |
| Hgene | >SERPINA3 | chr14:95081421 | chr3:148563211 | ENST00000467132 | + | 2 | 5 | 235_237 | 214 | 424 | DNA binding | . |
| Hgene | >SERPINA3 | chr14:95081421 | chr3:148563211 | ENST00000393078 | + | 2 | 5 | 369_394 | 214 | 424 | Region | Note=RCL |
| Hgene | >SERPINA3 | chr14:95081421 | chr3:148563211 | ENST00000393078 | + | 2 | 5 | 381_389 | 214 | 424 | Region | Note=O-glycosylated at one site |
| Hgene | >SERPINA3 | chr14:95081421 | chr3:148563211 | ENST00000393080 | + | 2 | 5 | 369_394 | 214 | 424 | Region | Note=RCL |
| Hgene | >SERPINA3 | chr14:95081421 | chr3:148563211 | ENST00000393080 | + | 2 | 5 | 381_389 | 214 | 424 | Region | Note=O-glycosylated at one site |
| Hgene | >SERPINA3 | chr14:95081421 | chr3:148563211 | ENST00000467132 | + | 2 | 5 | 369_394 | 214 | 424 | Region | Note=RCL |
| Hgene | >SERPINA3 | chr14:95081421 | chr3:148563211 | ENST00000467132 | + | 2 | 5 | 381_389 | 214 | 424 | Region | Note=O-glycosylated at one site |
| Tgene | CPB1 | chr14:95081421 | chr3:148563211 | ENST00000282957 | + | 7 | 11 | 176_179 | 259 | 418 | Region | Substrate binding |
| Tgene | CPB1 | chr14:95081421 | chr3:148563211 | ENST00000282957 | + | 7 | 11 | 251_252 | 259 | 418 | Region | Substrate binding |
| Tgene | CPB1 | chr14:95081421 | chr3:148563211 | ENST00000491148 | + | 8 | 12 | 176_179 | 259 | 418 | Region | Substrate binding |
| Tgene | CPB1 | chr14:95081421 | chr3:148563211 | ENST00000491148 | + | 8 | 12 | 251_252 | 259 | 418 | Region | Substrate binding |
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FusionGeneSequence for SERPINA3_CPB1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SERPINA3_ENST00000393078_chr14_95081421_+_CPB1_ENST00000491148_chr3_148563211_+_373aa MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLG AHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLI NDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYS YAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAI >In-frame_SERPINA3_ENST00000393078_chr14_95081421_+_CPB1_ENST00000282957_chr3_148563211_+_373aa MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLG AHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLI NDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYS YAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAI >In-frame_SERPINA3_ENST00000393080_chr14_95081421_+_CPB1_ENST00000491148_chr3_148563211_+_373aa MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLG AHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLI NDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYS YAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAI >In-frame_SERPINA3_ENST00000393080_chr14_95081421_+_CPB1_ENST00000282957_chr3_148563211_+_373aa MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLG AHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLI NDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYS YAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAI >In-frame_SERPINA3_ENST00000467132_chr14_95081421_+_CPB1_ENST00000491148_chr3_148563211_+_373aa MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLG AHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLI NDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYS YAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAI >In-frame_SERPINA3_ENST00000467132_chr14_95081421_+_CPB1_ENST00000282957_chr3_148563211_+_373aa MERMLPLLALGLLAAGFCPAVLCHPNSPLDEENLTQENQDRGTHVDLGLASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLG AHNTTLTEILKGLKFNLTETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLI NDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAYLTIHSYSQMMIYPYS YAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAGGSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAI |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SERPINA3_ENST00000393078_chr14_95081421_+_CPB1_ENST00000491148_chr3_148563211_+_1119nt ATGGAGAGAATGTTACCTCTCCTGGCTCTGGGGCTCTTGGCGGCTGGGTTCTGCCCTGCTGTCCTCTGCCACCCTAACAGCCCACTTGAC GAGGAGAATCTGACCCAGGAGAACCAAGACCGAGGGACACACGTGGACCTCGGATTAGCCTCCGCCAACGTGGACTTCGCTTTCAGCCTG TACAAGCAGTTAGTCCTGAAGGCCCCTGATAAGAATGTCATCTTCTCCCCACTGAGCATCTCCACCGCCTTGGCCTTCCTGTCTCTGGGG GCCCATAATACCACCCTGACAGAGATTCTCAAAGGCCTCAAGTTCAACCTCACGGAGACTTCTGAGGCAGAAATTCACCAGAGCTTCCAG CACCTCCTGCGCACCCTCAATCAGTCCAGCGATGAGCTGCAGCTGAGTATGGGAAATGCCATGTTTGTCAAAGAGCAACTCAGTCTGCTG GACAGGTTCACGGAGGATGCCAAGAGGCTGTATGGCTCCGAGGCCTTTGCCACTGACTTTCAGGACTCAGCTGCAGCTAAGAAGCTCATC AACGACTACGTGAAGAATGGAACTAGGGGGAAAATCACAGATCTGATCAAGGACCTTGACTCGCAGACAATGATGGTCCTGGTGAATTAC ATCTTCTTTAAAGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCC CTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCA TATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAG TACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTC ACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATC >In-frame_SERPINA3_ENST00000393078_chr14_95081421_+_CPB1_ENST00000282957_chr3_148563211_+_1119nt ATGGAGAGAATGTTACCTCTCCTGGCTCTGGGGCTCTTGGCGGCTGGGTTCTGCCCTGCTGTCCTCTGCCACCCTAACAGCCCACTTGAC GAGGAGAATCTGACCCAGGAGAACCAAGACCGAGGGACACACGTGGACCTCGGATTAGCCTCCGCCAACGTGGACTTCGCTTTCAGCCTG TACAAGCAGTTAGTCCTGAAGGCCCCTGATAAGAATGTCATCTTCTCCCCACTGAGCATCTCCACCGCCTTGGCCTTCCTGTCTCTGGGG GCCCATAATACCACCCTGACAGAGATTCTCAAAGGCCTCAAGTTCAACCTCACGGAGACTTCTGAGGCAGAAATTCACCAGAGCTTCCAG CACCTCCTGCGCACCCTCAATCAGTCCAGCGATGAGCTGCAGCTGAGTATGGGAAATGCCATGTTTGTCAAAGAGCAACTCAGTCTGCTG GACAGGTTCACGGAGGATGCCAAGAGGCTGTATGGCTCCGAGGCCTTTGCCACTGACTTTCAGGACTCAGCTGCAGCTAAGAAGCTCATC AACGACTACGTGAAGAATGGAACTAGGGGGAAAATCACAGATCTGATCAAGGACCTTGACTCGCAGACAATGATGGTCCTGGTGAATTAC ATCTTCTTTAAAGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCC CTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCA TATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAG TACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTC ACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATC >In-frame_SERPINA3_ENST00000393080_chr14_95081421_+_CPB1_ENST00000491148_chr3_148563211_+_1119nt ATGGAGAGAATGTTACCTCTCCTGGCTCTGGGGCTCTTGGCGGCTGGGTTCTGCCCTGCTGTCCTCTGCCACCCTAACAGCCCACTTGAC GAGGAGAATCTGACCCAGGAGAACCAAGACCGAGGGACACACGTGGACCTCGGATTAGCCTCCGCCAACGTGGACTTCGCTTTCAGCCTG TACAAGCAGTTAGTCCTGAAGGCCCCTGATAAGAATGTCATCTTCTCCCCACTGAGCATCTCCACCGCCTTGGCCTTCCTGTCTCTGGGG GCCCATAATACCACCCTGACAGAGATTCTCAAAGGCCTCAAGTTCAACCTCACGGAGACTTCTGAGGCAGAAATTCACCAGAGCTTCCAG CACCTCCTGCGCACCCTCAATCAGTCCAGCGATGAGCTGCAGCTGAGTATGGGAAATGCCATGTTTGTCAAAGAGCAACTCAGTCTGCTG GACAGGTTCACGGAGGATGCCAAGAGGCTGTATGGCTCCGAGGCCTTTGCCACTGACTTTCAGGACTCAGCTGCAGCTAAGAAGCTCATC AACGACTACGTGAAGAATGGAACTAGGGGGAAAATCACAGATCTGATCAAGGACCTTGACTCGCAGACAATGATGGTCCTGGTGAATTAC ATCTTCTTTAAAGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCC CTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCA TATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAG TACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTC ACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATC >In-frame_SERPINA3_ENST00000393080_chr14_95081421_+_CPB1_ENST00000282957_chr3_148563211_+_1119nt ATGGAGAGAATGTTACCTCTCCTGGCTCTGGGGCTCTTGGCGGCTGGGTTCTGCCCTGCTGTCCTCTGCCACCCTAACAGCCCACTTGAC GAGGAGAATCTGACCCAGGAGAACCAAGACCGAGGGACACACGTGGACCTCGGATTAGCCTCCGCCAACGTGGACTTCGCTTTCAGCCTG TACAAGCAGTTAGTCCTGAAGGCCCCTGATAAGAATGTCATCTTCTCCCCACTGAGCATCTCCACCGCCTTGGCCTTCCTGTCTCTGGGG GCCCATAATACCACCCTGACAGAGATTCTCAAAGGCCTCAAGTTCAACCTCACGGAGACTTCTGAGGCAGAAATTCACCAGAGCTTCCAG CACCTCCTGCGCACCCTCAATCAGTCCAGCGATGAGCTGCAGCTGAGTATGGGAAATGCCATGTTTGTCAAAGAGCAACTCAGTCTGCTG GACAGGTTCACGGAGGATGCCAAGAGGCTGTATGGCTCCGAGGCCTTTGCCACTGACTTTCAGGACTCAGCTGCAGCTAAGAAGCTCATC AACGACTACGTGAAGAATGGAACTAGGGGGAAAATCACAGATCTGATCAAGGACCTTGACTCGCAGACAATGATGGTCCTGGTGAATTAC ATCTTCTTTAAAGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCC CTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCA TATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAG TACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTC ACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATC >In-frame_SERPINA3_ENST00000467132_chr14_95081421_+_CPB1_ENST00000491148_chr3_148563211_+_1119nt ATGGAGAGAATGTTACCTCTCCTGGCTCTGGGGCTCTTGGCGGCTGGGTTCTGCCCTGCTGTCCTCTGCCACCCTAACAGCCCACTTGAC GAGGAGAATCTGACCCAGGAGAACCAAGACCGAGGGACACACGTGGACCTCGGATTAGCCTCCGCCAACGTGGACTTCGCTTTCAGCCTG TACAAGCAGTTAGTCCTGAAGGCCCCTGATAAGAATGTCATCTTCTCCCCACTGAGCATCTCCACCGCCTTGGCCTTCCTGTCTCTGGGG GCCCATAATACCACCCTGACAGAGATTCTCAAAGGCCTCAAGTTCAACCTCACGGAGACTTCTGAGGCAGAAATTCACCAGAGCTTCCAG CACCTCCTGCGCACCCTCAATCAGTCCAGCGATGAGCTGCAGCTGAGTATGGGAAATGCCATGTTTGTCAAAGAGCAACTCAGTCTGCTG GACAGGTTCACGGAGGATGCCAAGAGGCTGTATGGCTCCGAGGCCTTTGCCACTGACTTTCAGGACTCAGCTGCAGCTAAGAAGCTCATC AACGACTACGTGAAGAATGGAACTAGGGGGAAAATCACAGATCTGATCAAGGACCTTGACTCGCAGACAATGATGGTCCTGGTGAATTAC ATCTTCTTTAAAGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCC CTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCA TATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAG TACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTC ACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATC >In-frame_SERPINA3_ENST00000467132_chr14_95081421_+_CPB1_ENST00000282957_chr3_148563211_+_1119nt ATGGAGAGAATGTTACCTCTCCTGGCTCTGGGGCTCTTGGCGGCTGGGTTCTGCCCTGCTGTCCTCTGCCACCCTAACAGCCCACTTGAC GAGGAGAATCTGACCCAGGAGAACCAAGACCGAGGGACACACGTGGACCTCGGATTAGCCTCCGCCAACGTGGACTTCGCTTTCAGCCTG TACAAGCAGTTAGTCCTGAAGGCCCCTGATAAGAATGTCATCTTCTCCCCACTGAGCATCTCCACCGCCTTGGCCTTCCTGTCTCTGGGG GCCCATAATACCACCCTGACAGAGATTCTCAAAGGCCTCAAGTTCAACCTCACGGAGACTTCTGAGGCAGAAATTCACCAGAGCTTCCAG CACCTCCTGCGCACCCTCAATCAGTCCAGCGATGAGCTGCAGCTGAGTATGGGAAATGCCATGTTTGTCAAAGAGCAACTCAGTCTGCTG GACAGGTTCACGGAGGATGCCAAGAGGCTGTATGGCTCCGAGGCCTTTGCCACTGACTTTCAGGACTCAGCTGCAGCTAAGAAGCTCATC AACGACTACGTGAAGAATGGAACTAGGGGGAAAATCACAGATCTGATCAAGGACCTTGACTCGCAGACAATGATGGTCCTGGTGAATTAC ATCTTCTTTAAAGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCC CTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCA TATGCTTACAAACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAG TACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTC ACCTTTGAACTTCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SERPINA3_ENST00000393078_chr14_95081421_+_CPB1_ENST00000491148_chr3_148563211_+_1383nt ATTCATGAAAATCCACTACTCCAGACAGACGGCTTTGGAATCCACCAGCTACATCCAGCTCCCTGAGGCAGAGTTGAGAATGGAGAGAAT GTTACCTCTCCTGGCTCTGGGGCTCTTGGCGGCTGGGTTCTGCCCTGCTGTCCTCTGCCACCCTAACAGCCCACTTGACGAGGAGAATCT GACCCAGGAGAACCAAGACCGAGGGACACACGTGGACCTCGGATTAGCCTCCGCCAACGTGGACTTCGCTTTCAGCCTGTACAAGCAGTT AGTCCTGAAGGCCCCTGATAAGAATGTCATCTTCTCCCCACTGAGCATCTCCACCGCCTTGGCCTTCCTGTCTCTGGGGGCCCATAATAC CACCCTGACAGAGATTCTCAAAGGCCTCAAGTTCAACCTCACGGAGACTTCTGAGGCAGAAATTCACCAGAGCTTCCAGCACCTCCTGCG CACCCTCAATCAGTCCAGCGATGAGCTGCAGCTGAGTATGGGAAATGCCATGTTTGTCAAAGAGCAACTCAGTCTGCTGGACAGGTTCAC GGAGGATGCCAAGAGGCTGTATGGCTCCGAGGCCTTTGCCACTGACTTTCAGGACTCAGCTGCAGCTAAGAAGCTCATCAACGACTACGT GAAGAATGGAACTAGGGGGAAAATCACAGATCTGATCAAGGACCTTGACTCGCAGACAATGATGGTCCTGGTGAATTACATCTTCTTTAA AGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTT CATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAA ACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGG CCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACT TCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGC CAGCTACGTCCTGGAACACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCAAAATTCTCATTTTTCATTTCTTTTCTTTCTTGAATT CTTATTTTGGTTTGCCTGGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTCTGGGTCTATTAAACTAGGTAGATCTTTTCGTATTGA >In-frame_SERPINA3_ENST00000393078_chr14_95081421_+_CPB1_ENST00000282957_chr3_148563211_+_1379nt ATTCATGAAAATCCACTACTCCAGACAGACGGCTTTGGAATCCACCAGCTACATCCAGCTCCCTGAGGCAGAGTTGAGAATGGAGAGAAT GTTACCTCTCCTGGCTCTGGGGCTCTTGGCGGCTGGGTTCTGCCCTGCTGTCCTCTGCCACCCTAACAGCCCACTTGACGAGGAGAATCT GACCCAGGAGAACCAAGACCGAGGGACACACGTGGACCTCGGATTAGCCTCCGCCAACGTGGACTTCGCTTTCAGCCTGTACAAGCAGTT AGTCCTGAAGGCCCCTGATAAGAATGTCATCTTCTCCCCACTGAGCATCTCCACCGCCTTGGCCTTCCTGTCTCTGGGGGCCCATAATAC CACCCTGACAGAGATTCTCAAAGGCCTCAAGTTCAACCTCACGGAGACTTCTGAGGCAGAAATTCACCAGAGCTTCCAGCACCTCCTGCG CACCCTCAATCAGTCCAGCGATGAGCTGCAGCTGAGTATGGGAAATGCCATGTTTGTCAAAGAGCAACTCAGTCTGCTGGACAGGTTCAC GGAGGATGCCAAGAGGCTGTATGGCTCCGAGGCCTTTGCCACTGACTTTCAGGACTCAGCTGCAGCTAAGAAGCTCATCAACGACTACGT GAAGAATGGAACTAGGGGGAAAATCACAGATCTGATCAAGGACCTTGACTCGCAGACAATGATGGTCCTGGTGAATTACATCTTCTTTAA AGAAATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTT CATCCGCAACAAACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAA ACTCGGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGG CCCGGGAGCTACAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACT TCGAGATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGC CAGCTACGTCCTGGAACACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCAAAATTCTCATTTTTCATTTCTTTTCTTTCTTGAATT CTTATTTTGGTTTGCCTGGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTCTGGGTCTATTAAACTAGGTAGATCTTTTCGTATTGA >In-frame_SERPINA3_ENST00000393080_chr14_95081421_+_CPB1_ENST00000491148_chr3_148563211_+_1372nt AAAATCCACTACTCCAGACAGACGGCTTTGGAATCCACCAGCTACATCCAGCTCCCTGAGAGTTGAGAATGGAGAGAATGTTACCTCTCC TGGCTCTGGGGCTCTTGGCGGCTGGGTTCTGCCCTGCTGTCCTCTGCCACCCTAACAGCCCACTTGACGAGGAGAATCTGACCCAGGAGA ACCAAGACCGAGGGACACACGTGGACCTCGGATTAGCCTCCGCCAACGTGGACTTCGCTTTCAGCCTGTACAAGCAGTTAGTCCTGAAGG CCCCTGATAAGAATGTCATCTTCTCCCCACTGAGCATCTCCACCGCCTTGGCCTTCCTGTCTCTGGGGGCCCATAATACCACCCTGACAG AGATTCTCAAAGGCCTCAAGTTCAACCTCACGGAGACTTCTGAGGCAGAAATTCACCAGAGCTTCCAGCACCTCCTGCGCACCCTCAATC AGTCCAGCGATGAGCTGCAGCTGAGTATGGGAAATGCCATGTTTGTCAAAGAGCAACTCAGTCTGCTGGACAGGTTCACGGAGGATGCCA AGAGGCTGTATGGCTCCGAGGCCTTTGCCACTGACTTTCAGGACTCAGCTGCAGCTAAGAAGCTCATCAACGACTACGTGAAGAATGGAA CTAGGGGGAAAATCACAGATCTGATCAAGGACCTTGACTCGCAGACAATGATGGTCCTGGTGAATTACATCTTCTTTAAAGAAATTGGAG CCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACA AACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGA ACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTA CAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAG GCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCC TGGAACACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCAAAATTCTCATTTTTCATTTCTTTTCTTTCTTGAATTCTTATTTTGGT TTGCCTGGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTCTGGGTCTATTAAACTAGGTAGATCTTTTCGTATTGATCATAATAAAA >In-frame_SERPINA3_ENST00000393080_chr14_95081421_+_CPB1_ENST00000282957_chr3_148563211_+_1368nt AAAATCCACTACTCCAGACAGACGGCTTTGGAATCCACCAGCTACATCCAGCTCCCTGAGAGTTGAGAATGGAGAGAATGTTACCTCTCC TGGCTCTGGGGCTCTTGGCGGCTGGGTTCTGCCCTGCTGTCCTCTGCCACCCTAACAGCCCACTTGACGAGGAGAATCTGACCCAGGAGA ACCAAGACCGAGGGACACACGTGGACCTCGGATTAGCCTCCGCCAACGTGGACTTCGCTTTCAGCCTGTACAAGCAGTTAGTCCTGAAGG CCCCTGATAAGAATGTCATCTTCTCCCCACTGAGCATCTCCACCGCCTTGGCCTTCCTGTCTCTGGGGGCCCATAATACCACCCTGACAG AGATTCTCAAAGGCCTCAAGTTCAACCTCACGGAGACTTCTGAGGCAGAAATTCACCAGAGCTTCCAGCACCTCCTGCGCACCCTCAATC AGTCCAGCGATGAGCTGCAGCTGAGTATGGGAAATGCCATGTTTGTCAAAGAGCAACTCAGTCTGCTGGACAGGTTCACGGAGGATGCCA AGAGGCTGTATGGCTCCGAGGCCTTTGCCACTGACTTTCAGGACTCAGCTGCAGCTAAGAAGCTCATCAACGACTACGTGAAGAATGGAA CTAGGGGGAAAATCACAGATCTGATCAAGGACCTTGACTCGCAGACAATGATGGTCCTGGTGAATTACATCTTCTTTAAAGAAATTGGAG CCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACA AACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGA ACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTA CAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAG GCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCC TGGAACACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCAAAATTCTCATTTTTCATTTCTTTTCTTTCTTGAATTCTTATTTTGGT TTGCCTGGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTCTGGGTCTATTAAACTAGGTAGATCTTTTCGTATTGATCATAATAAAA >In-frame_SERPINA3_ENST00000467132_chr14_95081421_+_CPB1_ENST00000491148_chr3_148563211_+_2452nt ACTACTCCAGACAGACGGCTTTGGAATCCACCAGCTACATCCAGCTCCCTGAGGACTGAGTGGGCGGAGGCTGAAGGTGAATAATCTTGT TTGCTGCGGTCACCGGCTTGGAACTCAGCCCTTCCAGGGTCTCTTGTGCAGTAGCTCATGGCTCTTCTCTGGCTTGTAGTTTCAGGAAAG GGGTAGTATGGGAGGTGGTGACTGCTCGGTACGTCTAATATGAACCAGGTGCCTTCATCATTTATCTCACCTGAGCCACTTAACAGGTTG TGCAGAGACGGAAACAGGTTGAGAGATGTACAGTCACCTGCTTGCCAGTACACAGCAATCAAAAGTGGCCAAAATAAAATCCCAGTCCAA GTCTGGGAGACTCCAAAGCCCTCTCTGCCTTCTCCCCACTAAGAGGCCCTTCCAGGCTTATGGTGGACACAGACACCACGTGGCAACCTG GCAGGGGCAGAGAAGAACATTTGCCTTTCTTTGGTCTTGCTGCCAACCATTATCAGGGCCATCGAGGCTCCAGACACTGTACCAGGGACT TTCATTTCCCTCTCTCAGTCGACCCTCACTGCCACCCAGCATCACATCGTGGAGGCCTGTGGAGGCCACACCACGTGACATCTAGAGGCT GGGAGAGTCACTGTGGCCTCTATCTCTGCCCAGGGCTCCTTCATCCCTGGGTTCTACTTTGGTGGCAGTTGGGAGAATGAAGGAAGGGAG CCCCTGCTTTCTAATCCCCTAGGATGAGATCTGCTCACCAAGCAGGAGAGGAGCAGGCATTCTGATTGGACTGAACCTCGGACCCCCCAT CAGCTTACAGACCGAGGAGCCAGGCAAACCTGGCTGCCCACTGGGCTCCTTTACCTGTTTGCTGTATGATCTTGGGCAAGCCCCCTCACC GCTCTGTGCCCGGCTTTTCCACTGCAAGAAAATGGCAACAATTATGGTACCTACCTCAAAGGGTGAAATGAAGCAGAGTGATGTGTGTCG GGTGCCCCAGAGAGCACCTACCTGAGGGAGGCTCCAAAGCTAGCAAGAGGCAGCAGGACAGGGACCAGGACGCAGGCTGGGTGGAGGGCA GTGGGAGGTGGTCGGGGCTCCATCTGGCCCTCTGAGACTTAAAGGAGCTTTGCTTTTCAGAGTTGAGAATGGAGAGAATGTTACCTCTCC TGGCTCTGGGGCTCTTGGCGGCTGGGTTCTGCCCTGCTGTCCTCTGCCACCCTAACAGCCCACTTGACGAGGAGAATCTGACCCAGGAGA ACCAAGACCGAGGGACACACGTGGACCTCGGATTAGCCTCCGCCAACGTGGACTTCGCTTTCAGCCTGTACAAGCAGTTAGTCCTGAAGG CCCCTGATAAGAATGTCATCTTCTCCCCACTGAGCATCTCCACCGCCTTGGCCTTCCTGTCTCTGGGGGCCCATAATACCACCCTGACAG AGATTCTCAAAGGCCTCAAGTTCAACCTCACGGAGACTTCTGAGGCAGAAATTCACCAGAGCTTCCAGCACCTCCTGCGCACCCTCAATC AGTCCAGCGATGAGCTGCAGCTGAGTATGGGAAATGCCATGTTTGTCAAAGAGCAACTCAGTCTGCTGGACAGGTTCACGGAGGATGCCA AGAGGCTGTATGGCTCCGAGGCCTTTGCCACTGACTTTCAGGACTCAGCTGCAGCTAAGAAGCTCATCAACGACTACGTGAAGAATGGAA CTAGGGGGAAAATCACAGATCTGATCAAGGACCTTGACTCGCAGACAATGATGGTCCTGGTGAATTACATCTTCTTTAAAGAAATTGGAG CCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACA AACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGA ACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTA CAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAG GCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCC TGGAACACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCAAAATTCTCATTTTTCATTTCTTTTCTTTCTTGAATTCTTATTTTGGT TTGCCTGGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTCTGGGTCTATTAAACTAGGTAGATCTTTTCGTATTGATCATAATAAAA >In-frame_SERPINA3_ENST00000467132_chr14_95081421_+_CPB1_ENST00000282957_chr3_148563211_+_2448nt ACTACTCCAGACAGACGGCTTTGGAATCCACCAGCTACATCCAGCTCCCTGAGGACTGAGTGGGCGGAGGCTGAAGGTGAATAATCTTGT TTGCTGCGGTCACCGGCTTGGAACTCAGCCCTTCCAGGGTCTCTTGTGCAGTAGCTCATGGCTCTTCTCTGGCTTGTAGTTTCAGGAAAG GGGTAGTATGGGAGGTGGTGACTGCTCGGTACGTCTAATATGAACCAGGTGCCTTCATCATTTATCTCACCTGAGCCACTTAACAGGTTG TGCAGAGACGGAAACAGGTTGAGAGATGTACAGTCACCTGCTTGCCAGTACACAGCAATCAAAAGTGGCCAAAATAAAATCCCAGTCCAA GTCTGGGAGACTCCAAAGCCCTCTCTGCCTTCTCCCCACTAAGAGGCCCTTCCAGGCTTATGGTGGACACAGACACCACGTGGCAACCTG GCAGGGGCAGAGAAGAACATTTGCCTTTCTTTGGTCTTGCTGCCAACCATTATCAGGGCCATCGAGGCTCCAGACACTGTACCAGGGACT TTCATTTCCCTCTCTCAGTCGACCCTCACTGCCACCCAGCATCACATCGTGGAGGCCTGTGGAGGCCACACCACGTGACATCTAGAGGCT GGGAGAGTCACTGTGGCCTCTATCTCTGCCCAGGGCTCCTTCATCCCTGGGTTCTACTTTGGTGGCAGTTGGGAGAATGAAGGAAGGGAG CCCCTGCTTTCTAATCCCCTAGGATGAGATCTGCTCACCAAGCAGGAGAGGAGCAGGCATTCTGATTGGACTGAACCTCGGACCCCCCAT CAGCTTACAGACCGAGGAGCCAGGCAAACCTGGCTGCCCACTGGGCTCCTTTACCTGTTTGCTGTATGATCTTGGGCAAGCCCCCTCACC GCTCTGTGCCCGGCTTTTCCACTGCAAGAAAATGGCAACAATTATGGTACCTACCTCAAAGGGTGAAATGAAGCAGAGTGATGTGTGTCG GGTGCCCCAGAGAGCACCTACCTGAGGGAGGCTCCAAAGCTAGCAAGAGGCAGCAGGACAGGGACCAGGACGCAGGCTGGGTGGAGGGCA GTGGGAGGTGGTCGGGGCTCCATCTGGCCCTCTGAGACTTAAAGGAGCTTTGCTTTTCAGAGTTGAGAATGGAGAGAATGTTACCTCTCC TGGCTCTGGGGCTCTTGGCGGCTGGGTTCTGCCCTGCTGTCCTCTGCCACCCTAACAGCCCACTTGACGAGGAGAATCTGACCCAGGAGA ACCAAGACCGAGGGACACACGTGGACCTCGGATTAGCCTCCGCCAACGTGGACTTCGCTTTCAGCCTGTACAAGCAGTTAGTCCTGAAGG CCCCTGATAAGAATGTCATCTTCTCCCCACTGAGCATCTCCACCGCCTTGGCCTTCCTGTCTCTGGGGGCCCATAATACCACCCTGACAG AGATTCTCAAAGGCCTCAAGTTCAACCTCACGGAGACTTCTGAGGCAGAAATTCACCAGAGCTTCCAGCACCTCCTGCGCACCCTCAATC AGTCCAGCGATGAGCTGCAGCTGAGTATGGGAAATGCCATGTTTGTCAAAGAGCAACTCAGTCTGCTGGACAGGTTCACGGAGGATGCCA AGAGGCTGTATGGCTCCGAGGCCTTTGCCACTGACTTTCAGGACTCAGCTGCAGCTAAGAAGCTCATCAACGACTACGTGAAGAATGGAA CTAGGGGGAAAATCACAGATCTGATCAAGGACCTTGACTCGCAGACAATGATGGTCCTGGTGAATTACATCTTCTTTAAAGAAATTGGAG CCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAAAAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACA AACTCTCTTCCATCAAGGCATATCTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAAACTCGGTGAGA ACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCACTGCACGGCACCAAGTACACATATGGCCCGGGAGCTA CAACAATCTATCCTGCTGCTGGGGGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGAGATACAG GCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAGACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCC TGGAACACCTGTACTAGTTGAGAAAGCTGATGGCCTTGTTTCAAAATTCTCATTTTTCATTTCTTTTCTTTCTTGAATTCTTATTTTGGT TTGCCTGGATGTTTTGCAGATCCCAATCTTTCTTTTAAGCTTCTGGGTCTATTAAACTAGGTAGATCTTTTCGTATTGATCATAATAAAA |
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FusionGenePPI for SERPINA3_CPB1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SERPINA3 | DNAJC1, ELANE, KLK2, PSMA3, ATP6V1B1, LAMC3, ZNRD1, ADH1B, LMNB1, NFKB1, ABCC5, GDPD1, DDX19B, C16orf70, KLK13, TBC1D22B, DDX31, ZIC1, SNX27, FAM60A, MPI, CDK15 | CPB1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SERPINA3_CPB1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | SERPINA3 | P01011 | DB01593 | Zinc | Alpha-1-antichymotrypsin | small molecule | approved|investigational |
| Tgene | CPB1 | P15086 | DB04272 | Citric Acid | Carboxypeptidase B | small molecule | approved|nutraceutical|vet_approved |
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RelatedDiseases for SERPINA3_CPB1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | SERPINA3 | C0023794 | Lipoidosis | 3 | CTD_human |
| Hgene | SERPINA3 | C0033578 | Prostatic Neoplasms | 1 | CTD_human |
| Hgene | SERPINA3 | C0033975 | Psychotic Disorders | 1 | PSYGENET |
| Hgene | SERPINA3 | C0349204 | Nonorganic psychosis | 1 | PSYGENET |
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