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Fusion gene ID: 32770 |
FusionGeneSummary for SCAPER_CEP120 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SCAPER_CEP120 | Fusion gene ID: 32770 | Hgene | Tgene | Gene symbol | SCAPER | CEP120 | Gene ID | 49855 | 153241 |
| Gene name | S-phase cyclin A associated protein in the ER | centrosomal protein 120 | |
| Synonyms | MSTP063|ZNF291|Zfp291 | CCDC100|JBTS31|SRTD13 | |
| Cytomap | 15q24.3 | 5q23.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | S phase cyclin A-associated protein in the endoplasmic reticulumzinc finger protein 291 | centrosomal protein of 120 kDacentrosomal protein 120kDacoiled-coil domain-containing protein 100 | |
| Modification date | 20180519 | 20180519 | |
| UniProtAcc | Q9BY12 | Q8N960 | |
| Ensembl transtripts involved in fusion gene | ENST00000538941, ENST00000563290, ENST00000324767, ENST00000562890, | ENST00000306467, ENST00000306481, ENST00000328236, ENST00000395431, ENST00000515110, | |
| Fusion gene scores | * DoF score | 7 X 6 X 7=294 | 1 X 1 X 1=1 |
| # samples | 7 | 1 | |
| ** MAII score | log2(7/294*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: SCAPER [Title/Abstract] AND CEP120 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | COAD | TCGA-AA-A02K-01A | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000538941 | ENST00000306467 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-3CDS | ENST00000538941 | ENST00000306481 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-3CDS | ENST00000538941 | ENST00000328236 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-intron | ENST00000538941 | ENST00000395431 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-intron | ENST00000538941 | ENST00000515110 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| Frame-shift | ENST00000563290 | ENST00000306467 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| Frame-shift | ENST00000563290 | ENST00000306481 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| Frame-shift | ENST00000563290 | ENST00000328236 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| 5CDS-intron | ENST00000563290 | ENST00000395431 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| 5CDS-intron | ENST00000563290 | ENST00000515110 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| In-frame | ENST00000324767 | ENST00000306467 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| In-frame | ENST00000324767 | ENST00000306481 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| In-frame | ENST00000324767 | ENST00000328236 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| 5CDS-intron | ENST00000324767 | ENST00000395431 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| 5CDS-intron | ENST00000324767 | ENST00000515110 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-3CDS | ENST00000562890 | ENST00000306467 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-3CDS | ENST00000562890 | ENST00000306481 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-3CDS | ENST00000562890 | ENST00000328236 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-intron | ENST00000562890 | ENST00000395431 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
| intron-intron | ENST00000562890 | ENST00000515110 | SCAPER | chr15 | 77176153 | - | CEP120 | chr5 | 122685783 | - |
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FusionProtFeatures for SCAPER_CEP120 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SCAPER | CEP120 |
| CCNA2/CDK2 regulatory protein that transiently maintainsCCNA2 in the cytoplasm. {ECO:0000269|PubMed:17698606}. | Plays a role in the microtubule-dependent coupling ofthe nucleus and the centrosome. Involved in the processes thatregulate centrosome-mediated interkinetic nuclear migration (INM)of neural progenitors and for proper positioning of neurons duringbrain development. Also implicated in the migration andselfrenewal of neural progenitors. Required for centrioleduplication and maturation during mitosis and subsequentciliogenesis (By similarity). Required for the recruitment ofCEP295 to the proximal end of new-born centrioles at thecentriolar microtubule wall during early S phase in a PLK4-dependent manner (PubMed:27185865). {ECO:0000250|UniProtKB:Q7TSG1,ECO:0000269|PubMed:27185865}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for SCAPER_CEP120 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SCAPER_ENST00000324767_chr15_77176153_-_CEP120_ENST00000306467_chr5_122685783_-_129aa MMREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRL >In-frame_SCAPER_ENST00000324767_chr15_77176153_-_CEP120_ENST00000306481_chr5_122685783_-_129aa MMREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRL >In-frame_SCAPER_ENST00000324767_chr15_77176153_-_CEP120_ENST00000328236_chr5_122685783_-_129aa MMREQESQMARLKKQQEELEQMRLRYLAAEEKDTVKTERQELLDIRNELNRLRQQEQKQYQDSTEIASGKKDGPHGSVLEEGLDDYLTRL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SCAPER_ENST00000324767_chr15_77176153_-_CEP120_ENST00000306467_chr5_122685783_-_387nt ATGATGAGGGAGCAAGAAAGTCAAATGGCTCGTCTTAAAAAACAGCAGGAAGAATTGGAACAGATGAGACTACGTTACCTTGCCGCTGAG GAAAAAGATACAGTAAAAACCGAGCGACAAGAATTGTTGGATATAAGAAATGAATTGAACAGGTTAAGGCAACAAGAGCAAAAACAATAC CAGGATTCCACAGAGATTGCAAGTGGAAAAAAGGATGGCCCCCATGGCAGTGTATTGGAAGAAGGTTTGGATGATTATTTGACTCGCCTG ATAGAAGAAAGGGATACTTTGATGAGAACGGGTGTGTATAATCACGAGGATCGAATAATAAGTGAACTCGACCGACAGATCAGAGAGATT >In-frame_SCAPER_ENST00000324767_chr15_77176153_-_CEP120_ENST00000306481_chr5_122685783_-_387nt ATGATGAGGGAGCAAGAAAGTCAAATGGCTCGTCTTAAAAAACAGCAGGAAGAATTGGAACAGATGAGACTACGTTACCTTGCCGCTGAG GAAAAAGATACAGTAAAAACCGAGCGACAAGAATTGTTGGATATAAGAAATGAATTGAACAGGTTAAGGCAACAAGAGCAAAAACAATAC CAGGATTCCACAGAGATTGCAAGTGGAAAAAAGGATGGCCCCCATGGCAGTGTATTGGAAGAAGGTTTGGATGATTATTTGACTCGCCTG ATAGAAGAAAGGGATACTTTGATGAGAACGGGTGTGTATAATCACGAGGATCGAATAATAAGTGAACTCGACCGACAGATCAGAGAGATT >In-frame_SCAPER_ENST00000324767_chr15_77176153_-_CEP120_ENST00000328236_chr5_122685783_-_387nt ATGATGAGGGAGCAAGAAAGTCAAATGGCTCGTCTTAAAAAACAGCAGGAAGAATTGGAACAGATGAGACTACGTTACCTTGCCGCTGAG GAAAAAGATACAGTAAAAACCGAGCGACAAGAATTGTTGGATATAAGAAATGAATTGAACAGGTTAAGGCAACAAGAGCAAAAACAATAC CAGGATTCCACAGAGATTGCAAGTGGAAAAAAGGATGGCCCCCATGGCAGTGTATTGGAAGAAGGTTTGGATGATTATTTGACTCGCCTG ATAGAAGAAAGGGATACTTTGATGAGAACGGGTGTGTATAATCACGAGGATCGAATAATAAGTGAACTCGACCGACAGATCAGAGAGATT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SCAPER_ENST00000324767_chr15_77176153_-_CEP120_ENST00000306467_chr5_122685783_-_2080nt GAGTCATACTCCATGGGTTTATGTGATAAATGATCTTGGCATAGAAGAGAATTTAAAGAATGATGAGGGAGCAAGAAAGTCAAATGGCTC GTCTTAAAAAACAGCAGGAAGAATTGGAACAGATGAGACTACGTTACCTTGCCGCTGAGGAAAAAGATACAGTAAAAACCGAGCGACAAG AATTGTTGGATATAAGAAATGAATTGAACAGGTTAAGGCAACAAGAGCAAAAACAATACCAGGATTCCACAGAGATTGCAAGTGGAAAAA AGGATGGCCCCCATGGCAGTGTATTGGAAGAAGGTTTGGATGATTATTTGACTCGCCTGATAGAAGAAAGGGATACTTTGATGAGAACGG GTGTGTATAATCACGAGGATCGAATAATAAGTGAACTCGACCGACAGATCAGAGAGATTTTGGCAAAAAGCAATGCCAGTAATTAATAAC ATTTGGAAAAGCTTTATAGAGACTCTAAGTCTAAATTTTAATTTCTTTGTAAAAACCTCAAAAGTGAGGAAAATGGATGTTTTAAAATGG TATTTTCAATTTTTTATAAGCAAAATTTTGTATGTTATTGTATAGTATTTATTTGATCTTATTTACTTTATGCTACCTCTCCCACACTGG TTTTATTTGTAATTTGCATTTATATACTCATTTTAAATGACTTTTCAGTGTTTTTCATAGTTTATAATCTGATGGCTAACTAACTTTCAA AACAGCTTTTAACTAAGTTTGTTGTAGGAGAAATGACTGCGGTAATTTCCAGTTCTATAATGTTTCATGTTGAGCCAAAAGAGTATATCT TGCACTTTAAAAACGCTGCGTCCTATTCCATTTGAATGTAAATTCTTAAAAGTTGAGACCAATTGTAACCAGTTTAACTCATTTTAGATG ACCTTTTTTTCTTATAATATTTGCAAGTGACAAGTTTGAAAACAAAGCAAGATCAGTGCAGAGAAGCCACATGACATGTTGGGTGACAGA TTGGTCATTTATTTAAATAAAGTTAATACAGATTAAATTTGTTTCAAGAGCTATTGAATTTTCAAATTTTCAGTGTATTTATAACTTTTA AGAACATGAAGTATTAGCTTAATATAGTTTTCTCTGTTGGTTTCTTCCTCAAGTTTGCATTGTTTTCTTTTGTTAAAATTAGAGATTTCT TTTTATTTTCCAGTTATAGTAATACTAGCTGTCAGCTTAAACCCTCTGTAATAGAACATGGAAACAGACACATAAAGACATTAGCTGAAA AAATAGAGTGAAAATCAACTATTTTTTACTCCCGCTAATTTCAATCAATCGTTTTCAAAAGCGCACGAGATTCACTCATTGGATTTATGC AGTGCCCTGTCTGTATAAAAACTCTTAAGAGTTCCTTTATATCATATTCTTCAGAGCCAACATTTGTCCTCAAAGCAACGTTTCCCACCT CCTTTTACTGAGTACTGAAAAAGTTTTAGCAAAGTCACAGATTAGGTTGAATTTCAAAATATATGTACTTTAAAAAGTTCTGATTTCCAA ATATAATAAAGTTAAAATTAAGTATATACTTTAGGAAGTTACCAATAACTTCCATCAAAGCAGAGTAGGATATATGGTAACATTAATTTT CGGTCATTTCAAATGAGGTATATTTCTTATTAGGGAAATTAAAGTCCCTATATTTATTATATATTTTTTCCTTATTAACAGAGTATTAAT CTAGTAAAAAATAACCCAGCAGTAAATAATAAAGAAATTACTGAATGAGAGGATAATGAATCTGAATCATAGCAGGAATTTGCAATATTA ATTATGGTTAGCTATTTTTCTCTCATTGATTTTTGTGCCACTTGAATGGAACAGAAGCAAGCCTTATGTTTTGGAAGGTCTGCGGTAAAA TGCTGTGACTGTTTACTTTCAATTGCATTGTGTGTTGCCTGTGACTGCTTTCAAACGCTAGAGGGGGCCTCTGATTTAAAGAAATAAAAA GGACTTTTCTAAAATGGATGTGTAGTTTATTTTGCCTTTTGTAAAGCTCTTTTGGCTATTGTAACTTAACAAATAAAATCATAATTGTGT >In-frame_SCAPER_ENST00000324767_chr15_77176153_-_CEP120_ENST00000306481_chr5_122685783_-_2079nt GAGTCATACTCCATGGGTTTATGTGATAAATGATCTTGGCATAGAAGAGAATTTAAAGAATGATGAGGGAGCAAGAAAGTCAAATGGCTC GTCTTAAAAAACAGCAGGAAGAATTGGAACAGATGAGACTACGTTACCTTGCCGCTGAGGAAAAAGATACAGTAAAAACCGAGCGACAAG AATTGTTGGATATAAGAAATGAATTGAACAGGTTAAGGCAACAAGAGCAAAAACAATACCAGGATTCCACAGAGATTGCAAGTGGAAAAA AGGATGGCCCCCATGGCAGTGTATTGGAAGAAGGTTTGGATGATTATTTGACTCGCCTGATAGAAGAAAGGGATACTTTGATGAGAACGG GTGTGTATAATCACGAGGATCGAATAATAAGTGAACTCGACCGACAGATCAGAGAGATTTTGGCAAAAAGCAATGCCAGTAATTAATAAC ATTTGGAAAAGCTTTATAGAGACTCTAAGTCTAAATTTTAATTTCTTTGTAAAAACCTCAAAAGTGAGGAAAATGGATGTTTTAAAATGG TATTTTCAATTTTTTATAAGCAAAATTTTGTATGTTATTGTATAGTATTTATTTGATCTTATTTACTTTATGCTACCTCTCCCACACTGG TTTTATTTGTAATTTGCATTTATATACTCATTTTAAATGACTTTTCAGTGTTTTTCATAGTTTATAATCTGATGGCTAACTAACTTTCAA AACAGCTTTTAACTAAGTTTGTTGTAGGAGAAATGACTGCGGTAATTTCCAGTTCTATAATGTTTCATGTTGAGCCAAAAGAGTATATCT TGCACTTTAAAAACGCTGCGTCCTATTCCATTTGAATGTAAATTCTTAAAAGTTGAGACCAATTGTAACCAGTTTAACTCATTTTAGATG ACCTTTTTTTCTTATAATATTTGCAAGTGACAAGTTTGAAAACAAAGCAAGATCAGTGCAGAGAAGCCACATGACATGTTGGGTGACAGA TTGGTCATTTATTTAAATAAAGTTAATACAGATTAAATTTGTTTCAAGAGCTATTGAATTTTCAAATTTTCAGTGTATTTATAACTTTTA AGAACATGAAGTATTAGCTTAATATAGTTTTCTCTGTTGGTTTCTTCCTCAAGTTTGCATTGTTTTCTTTTGTTAAAATTAGAGATTTCT TTTTATTTTCCAGTTATAGTAATACTAGCTGTCAGCTTAAACCCTCTGTAATAGAACATGGAAACAGACACATAAAGACATTAGCTGAAA AAATAGAGTGAAAATCAACTATTTTTTACTCCCGCTAATTTCAATCAATCGTTTTCAAAAGCGCACGAGATTCACTCATTGGATTTATGC AGTGCCCTGTCTGTATAAAAACTCTTAAGAGTTCCTTTATATCATATTCTTCAGAGCCAACATTTGTCCTCAAAGCAACGTTTCCCACCT CCTTTTACTGAGTACTGAAAAAGTTTTAGCAAAGTCACAGATTAGGTTGAATTTCAAAATATATGTACTTTAAAAAGTTCTGATTTCCAA ATATAATAAAGTTAAAATTAAGTATATACTTTAGGAAGTTACCAATAACTTCCATCAAAGCAGAGTAGGATATATGGTAACATTAATTTT CGGTCATTTCAAATGAGGTATATTTCTTATTAGGGAAATTAAAGTCCCTATATTTATTATATATTTTTTCCTTATTAACAGAGTATTAAT CTAGTAAAAAATAACCCAGCAGTAAATAATAAAGAAATTACTGAATGAGAGGATAATGAATCTGAATCATAGCAGGAATTTGCAATATTA ATTATGGTTAGCTATTTTTCTCTCATTGATTTTTGTGCCACTTGAATGGAACAGAAGCAAGCCTTATGTTTTGGAAGGTCTGCGGTAAAA TGCTGTGACTGTTTACTTTCAATTGCATTGTGTGTTGCCTGTGACTGCTTTCAAACGCTAGAGGGGGCCTCTGATTTAAAGAAATAAAAA GGACTTTTCTAAAATGGATGTGTAGTTTATTTTGCCTTTTGTAAAGCTCTTTTGGCTATTGTAACTTAACAAATAAAATCATAATTGTGT >In-frame_SCAPER_ENST00000324767_chr15_77176153_-_CEP120_ENST00000328236_chr5_122685783_-_2079nt GAGTCATACTCCATGGGTTTATGTGATAAATGATCTTGGCATAGAAGAGAATTTAAAGAATGATGAGGGAGCAAGAAAGTCAAATGGCTC GTCTTAAAAAACAGCAGGAAGAATTGGAACAGATGAGACTACGTTACCTTGCCGCTGAGGAAAAAGATACAGTAAAAACCGAGCGACAAG AATTGTTGGATATAAGAAATGAATTGAACAGGTTAAGGCAACAAGAGCAAAAACAATACCAGGATTCCACAGAGATTGCAAGTGGAAAAA AGGATGGCCCCCATGGCAGTGTATTGGAAGAAGGTTTGGATGATTATTTGACTCGCCTGATAGAAGAAAGGGATACTTTGATGAGAACGG GTGTGTATAATCACGAGGATCGAATAATAAGTGAACTCGACCGACAGATCAGAGAGATTTTGGCAAAAAGCAATGCCAGTAATTAATAAC ATTTGGAAAAGCTTTATAGAGACTCTAAGTCTAAATTTTAATTTCTTTGTAAAAACCTCAAAAGTGAGGAAAATGGATGTTTTAAAATGG TATTTTCAATTTTTTATAAGCAAAATTTTGTATGTTATTGTATAGTATTTATTTGATCTTATTTACTTTATGCTACCTCTCCCACACTGG TTTTATTTGTAATTTGCATTTATATACTCATTTTAAATGACTTTTCAGTGTTTTTCATAGTTTATAATCTGATGGCTAACTAACTTTCAA AACAGCTTTTAACTAAGTTTGTTGTAGGAGAAATGACTGCGGTAATTTCCAGTTCTATAATGTTTCATGTTGAGCCAAAAGAGTATATCT TGCACTTTAAAAACGCTGCGTCCTATTCCATTTGAATGTAAATTCTTAAAAGTTGAGACCAATTGTAACCAGTTTAACTCATTTTAGATG ACCTTTTTTTCTTATAATATTTGCAAGTGACAAGTTTGAAAACAAAGCAAGATCAGTGCAGAGAAGCCACATGACATGTTGGGTGACAGA TTGGTCATTTATTTAAATAAAGTTAATACAGATTAAATTTGTTTCAAGAGCTATTGAATTTTCAAATTTTCAGTGTATTTATAACTTTTA AGAACATGAAGTATTAGCTTAATATAGTTTTCTCTGTTGGTTTCTTCCTCAAGTTTGCATTGTTTTCTTTTGTTAAAATTAGAGATTTCT TTTTATTTTCCAGTTATAGTAATACTAGCTGTCAGCTTAAACCCTCTGTAATAGAACATGGAAACAGACACATAAAGACATTAGCTGAAA AAATAGAGTGAAAATCAACTATTTTTTACTCCCGCTAATTTCAATCAATCGTTTTCAAAAGCGCACGAGATTCACTCATTGGATTTATGC AGTGCCCTGTCTGTATAAAAACTCTTAAGAGTTCCTTTATATCATATTCTTCAGAGCCAACATTTGTCCTCAAAGCAACGTTTCCCACCT CCTTTTACTGAGTACTGAAAAAGTTTTAGCAAAGTCACAGATTAGGTTGAATTTCAAAATATATGTACTTTAAAAAGTTCTGATTTCCAA ATATAATAAAGTTAAAATTAAGTATATACTTTAGGAAGTTACCAATAACTTCCATCAAAGCAGAGTAGGATATATGGTAACATTAATTTT CGGTCATTTCAAATGAGGTATATTTCTTATTAGGGAAATTAAAGTCCCTATATTTATTATATATTTTTTCCTTATTAACAGAGTATTAAT CTAGTAAAAAATAACCCAGCAGTAAATAATAAAGAAATTACTGAATGAGAGGATAATGAATCTGAATCATAGCAGGAATTTGCAATATTA ATTATGGTTAGCTATTTTTCTCTCATTGATTTTTGTGCCACTTGAATGGAACAGAAGCAAGCCTTATGTTTTGGAAGGTCTGCGGTAAAA TGCTGTGACTGTTTACTTTCAATTGCATTGTGTGTTGCCTGTGACTGCTTTCAAACGCTAGAGGGGGCCTCTGATTTAAAGAAATAAAAA GGACTTTTCTAAAATGGATGTGTAGTTTATTTTGCCTTTTGTAAAGCTCTTTTGGCTATTGTAACTTAACAAATAAAATCATAATTGTGT |
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FusionGenePPI for SCAPER_CEP120 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SCAPER | CALM1, HECW2, CCNA2, APPL1, MZT1 | CEP120 | STAT3, C9orf78, LTBR, CENPJ, CEP162, ANK2, PCM1, KIAA0753, ALMS1, ANAPC1, ARHGAP21, CEP131, BTF3, CNOT11, C2orf44, CAMSAP1, CASC5, CCDC138, CCDC66, CCDC77, CCP110, CDC123, CEP152, CEP170, CEP192, CEP350, CEP55, CEP72, CEP95, CEP97, CKAP2, CKB, CNTROB, CSPP1, DVL3, ECH1, EPPK1, FANCI, FGFR1OP, GPATCH1, HAUS1, HAUS2, HAUS3, HAUS4, HAUS5, HAUS6, HAUS7, HAUS8, IBTK, IPMK, KIAA0586, KIAA1671, CEP295, KIF14, LIMCH1, LRRC49, LTV1, LUZP1, MAP7D3, MED4, MPHOSPH9, NAP1L1, NAP1L4, NCAPD2, OFD1, PDCD2L, PIBF1, RAPGEF6, RPAP2, SDCCAG3, SPICE1, SSX2IP, TNRC6B, TP53, TP53BP2, TTC28, TTF2, TTK, UNC45A, TBC1D31, WDR83, WRAP73, XRN1, YEATS2, ZC2HC1A, CEP128, CEP135, ODF2, LCA5, MTX2, CHORDC1, HLX, NOL7, PSMG1, POMP |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SCAPER_CEP120 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SCAPER_CEP120 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | SCAPER | C3714756 | Intellectual Disability | 1 | CTD_human |
| Tgene | CEP120 | C4225378 | SHORT-RIB THORACIC DYSPLASIA 13 WITH OR WITHOUT POLYDACTYLY | 1 | UNIPROT |
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