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Fusion gene ID: 32642 |
FusionGeneSummary for SARNP_NT5DC3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: SARNP_NT5DC3 | Fusion gene ID: 32642 | Hgene | Tgene | Gene symbol | SARNP | NT5DC3 | Gene ID | 84324 | 51559 |
| Gene name | SAP domain containing ribonucleoprotein | 5'-nucleotidase domain containing 3 | |
| Synonyms | CIP29|HCC1|HSPC316|THO1 | TU12B1-TY|TU12B1TY | |
| Cytomap | 12q13.2 | 12q23.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | SAP domain-containing ribonucleoproteincytokine induced protein 29 kDacytokine-induced protein of 29 kDahepatocellular carcinoma 1nuclear protein Hcc-1proliferation associated cytokine-inducible protein CIP29 | 5'-nucleotidase domain-containing protein 3 | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | P82979 | Q86UY8 | |
| Ensembl transtripts involved in fusion gene | ENST00000444631, ENST00000336133, ENST00000552080, | ENST00000392876, ENST00000465502, | |
| Fusion gene scores | * DoF score | 10 X 5 X 8=400 | 3 X 2 X 2=12 |
| # samples | 11 | 3 | |
| ** MAII score | log2(11/400*10)=-1.86249647625006 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/12*10)=1.32192809488736 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: SARNP [Title/Abstract] AND NT5DC3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | SARNP | GO:0006406 | mRNA export from nucleus | 20844015 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | SARC | TCGA-DX-A2IZ-01A | SARNP | chr12 | 56188143 | - | NT5DC3 | chr12 | 104200707 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000444631 | ENST00000392876 | SARNP | chr12 | 56188143 | - | NT5DC3 | chr12 | 104200707 | - |
| 5CDS-intron | ENST00000444631 | ENST00000465502 | SARNP | chr12 | 56188143 | - | NT5DC3 | chr12 | 104200707 | - |
| Frame-shift | ENST00000336133 | ENST00000392876 | SARNP | chr12 | 56188143 | - | NT5DC3 | chr12 | 104200707 | - |
| 5CDS-intron | ENST00000336133 | ENST00000465502 | SARNP | chr12 | 56188143 | - | NT5DC3 | chr12 | 104200707 | - |
| Frame-shift | ENST00000552080 | ENST00000392876 | SARNP | chr12 | 56188143 | - | NT5DC3 | chr12 | 104200707 | - |
| 5CDS-intron | ENST00000552080 | ENST00000465502 | SARNP | chr12 | 56188143 | - | NT5DC3 | chr12 | 104200707 | - |
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FusionProtFeatures for SARNP_NT5DC3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| SARNP | NT5DC3 |
| Binds both single-stranded and double-stranded DNA withhigher affinity for the single-stranded form. Specifically bindsto scaffold/matrix attachment region DNA. Also binds single-stranded RNA. Enhances RNA unwinding activity of DDX39A. Mayparticipate in important transcriptional or translational controlof cell growth, metabolism and carcinogenesis. Component of theTREX complex which is thought to couple mRNA transcription,processing and nuclear export, and specifically associates withspliced mRNA and not with unspliced pre-mRNA. TREX is recruited tospliced mRNAs by a transcription-independent mechanism, binds tomRNA upstream of the exon-junction complex (EJC) and is recruitedin a splicing- and cap-dependent manner to a region near the 5'end of the mRNA where it functions in mRNA export to the cytoplasmvia the TAP/NFX1 pathway. The TREX complex is essential for theexport of Kaposi's sarcoma-associated herpesvirus (KSHV)intronless mRNAs and infectious virus production.{ECO:0000269|PubMed:15338056, ECO:0000269|PubMed:17196963,ECO:0000269|PubMed:20844015}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | SARNP | chr12:56188143 | chr12:104200707 | ENST00000336133 | - | 7 | 11 | 8_42 | 135 | 211 | Domain | SAP |
| Tgene | >NT5DC3 | chr12:56188143 | chr12:104200707 | ENST00000392876 | - | 1 | 14 | 251_259 | 131 | 549 | Region | Substrate binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | NT5DC3 | chr12:56188143 | chr12:104200707 | ENST00000392876 | - | 1 | 14 | 4_7 | 131 | 549 | Compositional bias | Note=Poly-Ala |
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FusionGeneSequence for SARNP_NT5DC3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_SARNP_ENST00000444631_chr12_56188143_-_NT5DC3_ENST00000392876_chr12_104200707_-_493aa MEEETKPIELPVKEEEPPEKTVDVAAEKKVVKITSEIPQTERMQKRAERFNVPVSLESKKAARAARFGISSVPTKVSSRNQEVXVXPKFC NSWTSLXCTAGSINEDRCFSLYPAGNCLQRPQCCPXXRSHXNVRGVPRALGADEXLLRKELSWKHDEAVHGHLLPARDDPPVLREXILPQ EQHRLXACASVQRCQGFNSRRPHQRNNVQSNXSRHXKVHLLCXADPRSVGQTGXSWQEDVSHHQXPQXLCGQRDELYRWERLEGPVRCGH CSGXEAKLLXXXAEAFPKDEXERCLTLGXNPXVAERPDIQAGXFIXIFEAYWMERIQSVVFWXPYIQXPGGFDPKAWLEDWCNHPRVEIX AQNHEHGAIHSNHDLAADLDWLIGTDAGSQRCXVTAGFAGVEKGKEGDARNDQEFLQCPVWKPVPHRPEPNLLPKAPVALRXHLHGVSEL |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_SARNP_ENST00000444631_chr12_56188143_-_NT5DC3_ENST00000392876_chr12_104200707_-_1480nt ATGGAAGAAGAAACAAAGCCCATTGAGCTCCCTGTCAAAGAGGAAGAACCCCCTGAAAAAACTGTTGATGTGGCAGCAGAGAAGAAAGTG GTGAAAATTACATCTGAAATACCACAGACTGAGAGAATGCAGAAGAGGGCTGAACGATTCAATGTACCTGTGAGCTTGGAGAGTAAGAAA GCTGCTCGGGCAGCTAGGTTTGGGATTTCTTCAGTTCCAACAAAAGTATCCAGCAGAAATCAGGAAGTATGAGTATGACCCAAATTTTGC AATTCGTGGACTTCATTATGATGTACAGCGGGCAGTATTAATGAAGATCGATGCTTTTCATTATATCCAGCTGGGAACTGTCTACAGAGG CCTCAGTGTTGTCCCTGATGAAGAAGTCATTGAAATGTACGAGGGGTCCCACGTGCCCTTGGAGCAGATGAGTGACTTTTACGGAAAGAG CTCTCATGGAAACACGATGAAGCAGTTCATGGACATCTTCTCCCTGCCCGAGATGACCCTCCTGTCCTGCGTGAATGAATACTTCCTCAA GAACAACATCGACTATGAGCCTGTGCATCTGTACAAAGATGTCAAGGATTCAATTCGAGACGTCCACATCAAAGGAATAATGTACAGAGC AATTGAAGCAGACATTGAAAAGTACATCTGCTATGCTGAGCAGACCCGCGCAGTGTTGGCCAAACTGGCTGATCATGGCAAGAAGATGTT TCTCATCACCAATAGCCCCAGTAGCTTTGTGGACAAAGGGATGAGTTATATCGTTGGGAAAGACTGGAGGGACCTGTTCGATGTGGTCAT TGTTCAGGCTGAGAAGCCAAACTTCTTTAATGATAAGCGGAGGCCTTTCCGAAAGATGAATGAGAAAGGTGTCTTACTCTGGGATAAAAT CCATAAGTTGCAGAAAGGCCAGATATACAAGCAGGGTAATTTATATGAATTTTTGAAGCTTACTGGATGGAGAGGATCCAGAGTGTTGTA TTTTGGTGACCATATATACAGTGACCTGGCGGATTTGACCCTAAAGCATGGCTGGAGGACTGGTGCAATCATCCCAGAGTTGAGATCTGA GCTCAAAATCATGAACACGGAGCAATACATTCAAACCATGACCTGGCTGCAGACCTTGACTGGCTTATTGGAACAGATGCAGGTTCACAG AGATGCTGAGTCACAGCTGGTTTTGCAGGAGTGGAAAAAGGAAAGGAAGGAGATGCGAGAAATGACCAAGAGTTTCTTCAATGCCCAGTT TGGAAGCCTGTTCCGCACAGACCAGAACCCAACCTACTTCCTAAGGCGCCTGTCGCGCTTCGCTGACATCTACATGGCGTCTCTGAGCTG CCTCCTGAACTATGACGTCAGCCACACTTTCTACCCCCGGAGGACTCCACTGCAGCACGAACTGCCCGCCTGGTCAGAAAGGCCCCCCAC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_SARNP_ENST00000444631_chr12_56188143_-_NT5DC3_ENST00000392876_chr12_104200707_-_7153nt AGTGGAGTGAGGGGTAACAAGATGGCGACCGAGACGGTGGAGCTCCATAAGCTAAAGCTTGCCGAACTAAAGCAAGAATGTCTTGCTCGT GGTTTGGAGACCAAGGGAATAAAGCAAGATCTTATCCACAGACTCCAGGCATATCTTGAAGAACATGGAAGAAGAAACAAAGCCCATTGA GCTCCCTGTCAAAGAGGAAGAACCCCCTGAAAAAACTGTTGATGTGGCAGCAGAGAAGAAAGTGGTGAAAATTACATCTGAAATACCACA GACTGAGAGAATGCAGAAGAGGGCTGAACGATTCAATGTACCTGTGAGCTTGGAGAGTAAGAAAGCTGCTCGGGCAGCTAGGTTTGGGAT TTCTTCAGTTCCAACAAAAGTATCCAGCAGAAATCAGGAAGTATGAGTATGACCCAAATTTTGCAATTCGTGGACTTCATTATGATGTAC AGCGGGCAGTATTAATGAAGATCGATGCTTTTCATTATATCCAGCTGGGAACTGTCTACAGAGGCCTCAGTGTTGTCCCTGATGAAGAAG TCATTGAAATGTACGAGGGGTCCCACGTGCCCTTGGAGCAGATGAGTGACTTTTACGGAAAGAGCTCTCATGGAAACACGATGAAGCAGT TCATGGACATCTTCTCCCTGCCCGAGATGACCCTCCTGTCCTGCGTGAATGAATACTTCCTCAAGAACAACATCGACTATGAGCCTGTGC ATCTGTACAAAGATGTCAAGGATTCAATTCGAGACGTCCACATCAAAGGAATAATGTACAGAGCAATTGAAGCAGACATTGAAAAGTACA TCTGCTATGCTGAGCAGACCCGCGCAGTGTTGGCCAAACTGGCTGATCATGGCAAGAAGATGTTTCTCATCACCAATAGCCCCAGTAGCT TTGTGGACAAAGGGATGAGTTATATCGTTGGGAAAGACTGGAGGGACCTGTTCGATGTGGTCATTGTTCAGGCTGAGAAGCCAAACTTCT TTAATGATAAGCGGAGGCCTTTCCGAAAGATGAATGAGAAAGGTGTCTTACTCTGGGATAAAATCCATAAGTTGCAGAAAGGCCAGATAT ACAAGCAGGGTAATTTATATGAATTTTTGAAGCTTACTGGATGGAGAGGATCCAGAGTGTTGTATTTTGGTGACCATATATACAGTGACC TGGCGGATTTGACCCTAAAGCATGGCTGGAGGACTGGTGCAATCATCCCAGAGTTGAGATCTGAGCTCAAAATCATGAACACGGAGCAAT ACATTCAAACCATGACCTGGCTGCAGACCTTGACTGGCTTATTGGAACAGATGCAGGTTCACAGAGATGCTGAGTCACAGCTGGTTTTGC AGGAGTGGAAAAAGGAAAGGAAGGAGATGCGAGAAATGACCAAGAGTTTCTTCAATGCCCAGTTTGGAAGCCTGTTCCGCACAGACCAGA ACCCAACCTACTTCCTAAGGCGCCTGTCGCGCTTCGCTGACATCTACATGGCGTCTCTGAGCTGCCTCCTGAACTATGACGTCAGCCACA CTTTCTACCCCCGGAGGACTCCACTGCAGCACGAACTGCCCGCCTGGTCAGAAAGGCCCCCCACCTTCGGAACCCCTCTCCTGCAGGAGG CCCAGGCCAAGTAGCCAAGGGCAAAAACTAGAAACTGTAACTGCCCCTGATTGGGCAGGCATGATGGGGTTGACTTCATGTGGGTCTGAG TGTTGCTTTTGGAAAAGATACAGATAAGCCTTTTGATATTTATTTTGTACCTTACGGAGAATAATTCTCCCAATGGTTAAGACAGGAGCT AGCAGCCCACCCCTCCAGCCTTTCCCCCCATGCAGGGCTGAAAGGCAAGCTTCACATTGGAACTCTGATTTTGCCTTTTTGTTTACTGAG GTCCTGGAACATCAGGTTTCCTGGGATAGGTGAGACCACTTGATGCCATGTCTGTATTCTAGCAGGTCAAGCTTGAAACGGTTCTTGACT CCTCCATGGAACATTTCCTGAACATTTACGGGCTATGCATTGGGAACTGCAGGGGCACAGTGATGGGCAAAGATTAGCTGCTTCCAGAAG GCTGATTTCGTGGGCTCCACAATGGTAAAACGCTGCTGTGAGTGGCAGAGAGGTTCCCCAGGTGATGGCCAGTTCCCAAATCATTTGGTA CTAAGGCTTTGACATTCTGGCACATCACATCAAATAGAACACAGCCTCCCTGGAAGGACTTAAGTGAGAAAGAACAAGAGAAGCTGCAAC TCCTGGACCCTTTTGTCCTCAGTGTGTGGTTCCTGCGTCCTTCCCCAGCATGGAGGAGGGCAGGAGAGAGGAGATGAGAGCTCTGGTCAA AACCTGCCAGCTAGTGGAACAGCCTTCTGTAGAGCCTTCTGCAAGAAACGAGTGGGTTTGAAGAACCAAAACATTTGTGGTAGGTCTCCC AGGAGCTTGTTAAACCTGGAAACACCACCTGAGTTGGTTTCATCTGCTCATTGGAAGAAAGAAAATGAACCAGGAAAAAGCATCTTTGTC ATGAAATGCTATGCCATGCCACCCACCCAGTTGAATTGGAATCCTGTTAAAACATGAGATTTACCAGAAACAGTCCTTTGTCTAGATGGA AACAAACAAGATCCTGGCTTCTCTCTAATGAGTTACCAACTGAGAGGTGCTTGGATTGGCCAGGGGAGGAGGAAGATGGCCACCACAACT TAGCCATGTCCAGCCTTCTCTTAGATTTCACTCCTGTGATGTTTGTGCGACTATTTGGGAGTTTGTGTAGTTTGTTTTTTTTTTTTTTGT TTTGTTTTGTTTTTTTTTAGATGTCTAAGATGGGAAAGGGCGAAGGACATTGAAGCTAAGGAATAGATATGACCTAGCTAACCAAGCTTT TCTCATTTCCTTCTGTTTTGTTTTGTTGAGATGGAGTTTTGCTCTTATTGCCCAGGCTGGAGTGCAGTGGCACAATCTCAGCTCACTGCA ACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACTACCACACCCAGCTAATTT TGTATTTCTAGTAGAGATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCGAACTCCCGACCTCAGATAATCTGCCCGCCTTGGCCTCCCA AATTGCTGGGATTACAGGTGTGAGCCACCGCACCTGGCCTGCTTTTTTCATTTCTTTCTAGGGGCAATGCAAGTGGCATGTATTCCTTTT GTTGGAGGGAAGAATCCTTAATTGCACCTGCATTTGTAGTATCCTTCAATGTAAAGTGCATATTTACTGCACTCTCTGAGTGCTATGGGA ATGTCTGCTGTTATTAGTTATGGGGCTGCTAATACTGTTTTAATTGCATATGCTATATCAATACTTCTGTTCAGATTAGCCTAATCTAGT ATTGCTAAAACTCATTTTAAGCTTTTGCGGTAACTTGTATATATTCTTAAATCTAAAGGATGGCAGGAACATGAGGGGAGCTTGTGGAGA GTGCTTGCTTATTCAACATTTTTATTGTGATAAATGTATGTAACCATCTATTGATGAAATCCAAGTCTGGCATTCCATGGGCTCCTTGCC AGATGGCAGAAACTTAATGAGTTATATAGCATCCTTTGTAATGCTGCTTGTTATAGTTGGAATGTACTTGTGATATTTGGCTGTATTTAA CTATAATGGTGAAGGTGACCCTTTAGATCCAATAAGGCTTCTCCCCATCTTCTACATTTTGTTATGAACACAGTAAGGCACAGTAGTATG TTCTTTTTTTGGAACAGGGTAGGCATTTTGTTTATTGTTTGCTTGCTTCTAGGTGTTTTCGCCATCAGGGTGTATTGGAGGCTGACACTT AATGGGTGTGTGTTGCGCCCAGAACTGCTCGGTGTCGGGGTTCTAAAAGAATGCGCTGGTGTTCTTGGCTTCAAGTTTCTGCTTTGGAGA AGCAGATTCAGGAAGTAGGTGTTGCTTAAAAATAATTCTTGGTTTTTATCTAATCAGATATTCATTGATTACCTACCAGGTGCCAGTTAT AGGGTGTTTTGTTTACTCAAGAATGAAGTAGAACTATTTTTAAAACCTGTTTCCATGAGTGTTCACGTTAGGTGACCTAAGCTTTGAAGG AGAAAAACATTTTTGGGTATGAATAATGAGTTTTGTAATCAATTCCCAGTTAGAAGAATTTCAGTCTCTGGGCCATTGAGCTTGGCAGTG TTGAGATCTCCCATGTGACAGAAGCCTGACATCTGGGCCACCAAGGCTCACTGACTGTGTACCTTGCAGACTGTAGACCCATGTCGTGGC GGTAACGGGGCCGAACACAGTCATTCCCATGTGAACGATGGAGGCACATCCCACTTTATTATTAATCCTTGTATATACTCAGTCAGGACA GATTTTAACTTGTCGCTGTCATGACTTTTTTTTTTTTTTTTTGAGGCAAGGTCTCGCTCTGTTGCCCATTCTGGAGTGCAGTGGTGTGAT CTCGGCTCACTGCAACCTCTTGCCTCCCAGGTTCAAGCAATTTTCGTGCCTCAGCCTCCCGAGTAGCTGGGACTACTGGTACATGCCACC AGGCCTGGCCAAGTTTTGTAGTTTTAATAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTAGCCTCAAGTGTTCTGC CCACCTCAGCCTTCCAAAGTGCTGGGATTCTGGGTGTGAGCCACTGTCATGCCTGGCCTCGTCATGACTCTTTTCTCTTTTTTTTTTTTT TTTTTTTTGAGATTTAGTTTTGCTCTTTTTGCCCAGGCCGGAGTGCAATGGCACGATCTTGGCTCACTCCAACCTCCGCCTCCTGGGTTC AAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCCACCACCACATCCAGCTAATTTTTTTGTATTTTTAGTAGAG ACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTTGGGTAATCCACCTGCCTTGGCCTCCCAAGGTGCTGGGATTACA GGCATGAGCCACCGTGCCCAGCCTATCATGACTCAACTGGGATCTGGCACACTGCACTGGGTGTTTTGTTCTCTGATGTGCACATTGATG AATGCATATTGGTACAAGGGAAATGAATCTGTTTTCAGCCATTTAAAAAATTGTGTTGTAAAGCAAACAAAAATAGCTTGAACATTTAAA AATTACTGTTTAATATTGTTTGACTGATTTTCTAAGAATTATGTGAACAATGATGAGTCCAGGGCAGCAGCCATCACAAATATGACAGTC CAGCAAGGCCCATGGAGGTCCCTTTGGAAGGGACTTGCACAGCTGATTTTCTTTTTCCAGTGTTGTTTTTACGGGTGAAACGTGGCTTTT GAAATACTTTAGTTGTTTGGCTTAGAGCTCCCACTTTCCCCCTAACATAGTGCCTGTCTGTTTTTTAAAACATTTTACCCTTCGGCACTA TTTTCTGCTATTCCCATTAATATTATGTAACATAAACCACTTGCTACTGATTTGGGCATATTACAGACTACAATTACTAGTTGCTTTGAA TGCATTGGCACTCTTAATTATTGCAAAGGAGAATTGAAAAGTAGTCTTGTGGTCCTAGTTAATTTAGCTTTGGGCAAACTAAGTGGCTTT TCTTCTGTCCTCTTCTCAAAAGGCCTTTTAAGCAGCAGAGACTGGGCTAAATACTGGAACTGAATTCCACTTTTCTGCCTGCTCATTTGC TGCCAAAGACCACTTGGGGCTCCTTGTCTAGAATGCTCTAAGACGAAATTTGGCCAGACACAGGGTTCCTTGATTGTTCTGTTCAACTAA TAGAGAACCTACATTTTGCCTTCTTAATATCGACTTTCTTTTGTACCAGGTTTTTCTTTCTTTCTTTTTTGCCTTAGGAGCTTAGCTCAA AGTTCAGCTAACCTTTGACACTACTAGTGTCATTTAGTAACAGTAATCTTTGACACTACTAGTGTCATTTAGGAGCTTAGCTCAAAGTTC AGCTAACCTTTGACACTGCTAGTGCGTTCAAGAAAGGGTAGGGAATGAAGTACCCTTAATGCAGGGTCAGCAAACTTTTCCTGTAAAAGG CCAGATAGGAAGTATTTTTGGCTTTTTGGGCTGTTTGCTTTTGCTACTACTACTGTGGGAATGACCATGGTCATGGCTGTGTTCCAGCAC AACTTGATTTACCAAGACAAGCTGTGGGCTGTATTTGGTCCTCAGGCTGTGGCTTGCTAGCCCCTGCTCTAATGGATTGTGTTGGCGGCA ATGGCAAGATTCCCTTGCTGAGAACATGCAGATGAATAACCTTATAGCTGGGATGCAGAGAGGAGAAAGTTCTGTAGGTAATAAGTGCAC TGTATTCCCTCTGAGCTACTTCCTGGGCATAGTTACATGTATGGCCAGTGTGTGTACTTGAGCCATCAGGCTCAGACACTTGTTGAATAT ACCTCTCATTGCATTAGTTTGTAATTGTGCTAGTGCTGGGTGCTGAGCTCAGCTGCCCGGATGACCTTTCCAGACTGAAGGACATACTCC CCTAACAGCTGGGAGTGCTGCTGGCTGGCCATTTACTTCCAGCCCTTATGAGGAGTTTCCCCTGCTGAAGAGCCCTGCCTGCCCCAGATC ATACCCCCTTCCTGCCTGTAACCCTTACCGGCTCCATATGGGGTACAAAGGGCTGGCCTCCTCACCCCAACTTGGGAAACCCTCTGGGGC CATCCCAGCTCCAGAGCCCCTTGTGGGGTCAGTGAGACCTCATTGTGGCCACATTACAGCCCAGTGCCTCTCCCTGACAAGCCTGTACCC AGCCGGCTCAGCCCACAGCACTGTCCTATGAACCTTCCTGCACGCCATTCTCCACCTCAGTATCTGCTTTCGGGGAACCCAACCTGCGAC AGTGCTTCTGTGTGTTTTCAGTCCTGCAGGTTTGAACTCTGACTTTGGAGACTTTTCCAGTTATCTCGTGGAATGACAGATTGTGCCTGT ATGATATCAGGCACAATTAATGCAAATTAGGCAGACCTATTTATTCTAGATGTGAATTTGCTATTTATTTTAAATGTTGATTTTATGTGT |
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FusionGenePPI for SARNP_NT5DC3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| SARNP | DDX39A, FUS, CSNK2B, CDK2, VHL, MRPL14, MRRF, VDAC3, NABP2, SRCAP, TIMM44, TAGLN, ZC3H11A, UBL4A, SBDS, MPLKIP, TBL2, MRPS31, STX7, SRPRB, THY1, SRRM2, RBMS1, SNRPC, TPX2, ACAA1, UBE2I, UBE4B, TIAL1, HSPD1, FN1, PLCG1, RIC8A, CSTB, DPP7, YARS, WDR61, ESR1, DNAJC14, EWSR1, THOC1, MPP1, PFKFB2, THOC2, THOC7, LIMK1, U2AF2, CCDC9, ZC3H14, FYTTD1, KBTBD7, ACIN1, CHTOP, C17orf85, RNPS1, PPIG, POLDIP3, MAGOH, PPP2R2D, PNN, CRIP2, THOC5, CPVL, EIF4A3, WDR45B, COPZ1, SUB1, CHORDC1, DIS3, SEPT7, PRCC, CDK5, SH3GLB1, DRG1, SCYL2, PDHA1 | NT5DC3 | ELAVL1, KIF11, EXOSC2, ZNF211, NT5DC2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for SARNP_NT5DC3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for SARNP_NT5DC3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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