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Fusion gene ID: 31985 |
FusionGeneSummary for RPLP2_ACPP |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RPLP2_ACPP | Fusion gene ID: 31985 | Hgene | Tgene | Gene symbol | RPLP2 | ACPP | Gene ID | 6181 | 55 |
| Gene name | ribosomal protein lateral stalk subunit P2 | acid phosphatase, prostate | |
| Synonyms | D11S2243E|LP2|P2|RPP2 | 5'-NT|ACP-3|ACP3 | |
| Cytomap | 11p15.5 | 3q22.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | 60S acidic ribosomal protein P2acidic ribosomal phosphoprotein P2large ribosomal subunit protein P2renal carcinoma antigen NY-REN-44ribosomal protein, large, P2 | prostatic acid phosphataseTMPaseecto-5'-nucleotidaseprostatic acid phosphotasethiamine monophosphatase | |
| Modification date | 20180522 | 20180519 | |
| UniProtAcc | P05387 | P15309 | |
| Ensembl transtripts involved in fusion gene | ENST00000321153, ENST00000532004, ENST00000530797, | ENST00000336375, ENST00000475741, ENST00000351273, ENST00000489084, | |
| Fusion gene scores | * DoF score | 13 X 11 X 4=572 | 3 X 3 X 1=9 |
| # samples | 13 | 3 | |
| ** MAII score | log2(13/572*10)=-2.13750352374993 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: RPLP2 [Title/Abstract] AND ACPP [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Tissue-specifically expressed gene involved fusion gene, inframe and retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ACPP | GO:0046085 | adenosine metabolic process | 18940592 |
| Tgene | ACPP | GO:0051289 | protein homotetramerization | 10639192 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | PRAD | TCGA-EJ-7125-01A | RPLP2 | chr11 | 812874 | + | ACPP | chr3 | 132036211 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000321153 | ENST00000336375 | RPLP2 | chr11 | 812874 | + | ACPP | chr3 | 132036211 | + |
| 5CDS-intron | ENST00000321153 | ENST00000475741 | RPLP2 | chr11 | 812874 | + | ACPP | chr3 | 132036211 | + |
| 5CDS-intron | ENST00000321153 | ENST00000351273 | RPLP2 | chr11 | 812874 | + | ACPP | chr3 | 132036211 | + |
| 5CDS-intron | ENST00000321153 | ENST00000489084 | RPLP2 | chr11 | 812874 | + | ACPP | chr3 | 132036211 | + |
| Frame-shift | ENST00000532004 | ENST00000336375 | RPLP2 | chr11 | 812874 | + | ACPP | chr3 | 132036211 | + |
| 5CDS-intron | ENST00000532004 | ENST00000475741 | RPLP2 | chr11 | 812874 | + | ACPP | chr3 | 132036211 | + |
| 5CDS-intron | ENST00000532004 | ENST00000351273 | RPLP2 | chr11 | 812874 | + | ACPP | chr3 | 132036211 | + |
| 5CDS-intron | ENST00000532004 | ENST00000489084 | RPLP2 | chr11 | 812874 | + | ACPP | chr3 | 132036211 | + |
| Frame-shift | ENST00000530797 | ENST00000336375 | RPLP2 | chr11 | 812874 | + | ACPP | chr3 | 132036211 | + |
| 5CDS-intron | ENST00000530797 | ENST00000475741 | RPLP2 | chr11 | 812874 | + | ACPP | chr3 | 132036211 | + |
| 5CDS-intron | ENST00000530797 | ENST00000351273 | RPLP2 | chr11 | 812874 | + | ACPP | chr3 | 132036211 | + |
| 5CDS-intron | ENST00000530797 | ENST00000489084 | RPLP2 | chr11 | 812874 | + | ACPP | chr3 | 132036211 | + |
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FusionProtFeatures for RPLP2_ACPP |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RPLP2 | ACPP |
| Plays an important role in the elongation step ofprotein synthesis. | A non-specific tyrosine phosphatase thatdephosphorylates a diverse number of substrates under acidicconditions (pH 4-6) including alkyl, aryl, and acyl orthophosphatemonoesters and phosphorylated proteins. Has lipid phosphataseactivity and inactivates lysophosphatidic acid in seminal plasma. Isoform 2: the cellular form also has ecto-5'-nucleotidase activity in dorsal root ganglion (DRG) neurons.Generates adenosine from AMP which acts as a pain suppressor. Actsas a tumor suppressor of prostate cancer through dephosphorylationof ERBB2 and deactivation of MAPK-mediated signaling. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for RPLP2_ACPP |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RPLP2_ENST00000321153_chr11_812874_+_ACPP_ENST00000336375_chr3_132036211_+_546aa MRYVASYLLAALGGNSSPSAKDIKKILDSVGIEADDDRLNKVISELNGKNIEDVIAQGIGKLASVPAGGAVAVSAAPGSAAPAAGSAPAA AEEKKDEKKEESEESDDDMGFGLFDXIPAPLQIKPFYTSSIPXLNSFPSTGFXSGSSSSXLLPETALLNMRAAPLLLARAASLSLGFLFL LFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKESSWPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDR TLMSAMTNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEFQKRLHPYKDFIATLGKLSGLHGQD LFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKLRELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDT TVSGLQMALDVYNGLLPPYASCHLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCSPSCPLERFAELVGPVIPQDWSTECMTTNSHQGT |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RPLP2_ENST00000321153_chr11_812874_+_ACPP_ENST00000336375_chr3_132036211_+_1638nt ATGCGCTACGTCGCCTCCTACCTGCTGGCTGCCCTAGGGGGCAACTCCTCCCCCAGCGCCAAGGACATCAAGAAGATCTTGGACAGCGTG GGTATCGAGGCGGACGACGACCGGCTCAACAAGGTTATCAGTGAGCTGAATGGAAAAAACATTGAAGACGTCATTGCCCAGGGTATTGGC AAGCTTGCCAGTGTACCTGCTGGTGGGGCTGTAGCCGTCTCTGCTGCCCCAGGCTCTGCAGCCCCTGCTGCTGGTTCTGCCCCTGCTGCA GCAGAGGAGAAGAAAGATGAGAAGAAGGAGGAGTCTGAAGAGTCAGATGATGACATGGGATTTGGCCTTTTTGATTAAATTCCTGCTCCC CTGCAAATAAAGCCTTTTTACACATCTTCAATCCCTTAATTAAATAGCTTCCCCTCTACAGGCTTTTGAAGTGGTAGCAGTTCCTCCTAA CTCCTGCCAGAAACAGCTCTCCTCAACATGAGAGCTGCACCCCTCCTCCTGGCCAGGGCAGCAAGCCTTAGCCTTGGCTTCTTGTTTCTG CTTTTTTTCTGGCTAGACCGAAGTGTACTAGCCAAGGAGTTGAAGTTTGTGACTTTGGTGTTTCGGCATGGAGACCGAAGTCCCATTGAC ACCTTTCCCACTGACCCCATAAAGGAATCCTCATGGCCACAAGGATTTGGCCAACTCACCCAGCTGGGCATGGAGCAGCATTATGAACTT GGAGAGTATATAAGAAAGAGATATAGAAAATTCTTGAATGAGTCCTATAAACATGAACAGGTTTATATTCGAAGCACAGACGTTGACCGG ACTTTGATGAGTGCTATGACAAACCTGGCAGCCCTGTTTCCCCCAGAAGGTGTCAGCATCTGGAATCCTATCCTACTCTGGCAGCCCATC CCGGTGCACACAGTTCCTCTTTCTGAAGATCAGTTGCTATACCTGCCTTTCAGGAACTGCCCTCGTTTTCAAGAACTTGAGAGTGAGACT TTGAAATCAGAGGAATTCCAGAAGAGGCTGCACCCTTATAAGGATTTTATAGCTACCTTGGGAAAACTTTCAGGATTACATGGCCAGGAC CTTTTTGGAATTTGGAGTAAAGTCTACGACCCTTTATATTGTGAGAGTGTTCACAATTTCACTTTACCCTCCTGGGCCACTGAGGACACC ATGACTAAGTTGAGAGAATTGTCAGAATTGTCCCTCCTGTCCCTCTATGGAATTCACAAGCAGAAAGAGAAATCTAGGCTCCAAGGGGGT GTCCTGGTCAATGAAATCCTCAATCACATGAAGAGAGCAACTCAGATACCAAGCTACAAAAAACTCATCATGTATTCTGCGCATGACACT ACTGTGAGTGGCCTACAGATGGCGCTAGATGTTTACAACGGACTCCTTCCTCCCTATGCTTCTTGCCACTTGACGGAATTGTACTTTGAG AAGGGGGAGTACTTTGTGGAGATGTACTATCGGAATGAGACGCAGCACGAGCCGTATCCCCTCATGCTACCTGGCTGCAGCCCCAGCTGT CCTCTGGAGAGGTTTGCTGAGCTGGTTGGCCCTGTGATCCCTCAAGACTGGTCCACGGAGTGTATGACCACAAACAGCCATCAAGGTACT |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RPLP2_ENST00000321153_chr11_812874_+_ACPP_ENST00000336375_chr3_132036211_+_3906nt GGCATGCTGGGGGTGCTAGGTACCGAAGGCAGATGCCGTCCCTTTGGACTCGCTTCGTCCAACGCCCCCACGAGTTTCGGTGGCCCTTCG CCCCACGCTATAAGAGCAGTCACTTCCGGAACTGCTGCCCTTCGCCTTTGCCGCGAAAAGTGCCTGACGGGGGCTGGGAAGGGGGAGGGG GAAGGAGTCAACGACTCCCTCCCCGTCGTCATTGGCTGAGCGCCTCGTGACGTCACTCTGAGGCGCCTCATGCGGCGCCGCGCACGGGTC CCAGAGCCTTCTGGGTAGCGGTTTAACCCCGCCTCTTGCGTCGGCGCCTTCCTTTTCCTCCCTGTCGCCACCGAGGTCGCACGCGTGAGA CTTCTCCGCCGCCTCCGCCGCAGACGCCGCCGCGATGCGCTACGTCGCCTCCTACCTGCTGGCTGCCCTAGGGGGCAACTCCTCCCCCAG CGCCAAGGACATCAAGAAGATCTTGGACAGCGTGGGTATCGAGGCGGACGACGACCGGCTCAACAAGGTTATCAGTGAGCTGAATGGAAA AAACATTGAAGACGTCATTGCCCAGGGTATTGGCAAGCTTGCCAGTGTACCTGCTGGTGGGGCTGTAGCCGTCTCTGCTGCCCCAGGCTC TGCAGCCCCTGCTGCTGGTTCTGCCCCTGCTGCAGCAGAGGAGAAGAAAGATGAGAAGAAGGAGGAGTCTGAAGAGTCAGATGATGACAT GGGATTTGGCCTTTTTGATTAAATTCCTGCTCCCCTGCAAATAAAGCCTTTTTACACATCTTCAATCCCTTAATTAAATAGCTTCCCCTC TACAGGCTTTTGAAGTGGTAGCAGTTCCTCCTAACTCCTGCCAGAAACAGCTCTCCTCAACATGAGAGCTGCACCCCTCCTCCTGGCCAG GGCAGCAAGCCTTAGCCTTGGCTTCTTGTTTCTGCTTTTTTTCTGGCTAGACCGAAGTGTACTAGCCAAGGAGTTGAAGTTTGTGACTTT GGTGTTTCGGCATGGAGACCGAAGTCCCATTGACACCTTTCCCACTGACCCCATAAAGGAATCCTCATGGCCACAAGGATTTGGCCAACT CACCCAGCTGGGCATGGAGCAGCATTATGAACTTGGAGAGTATATAAGAAAGAGATATAGAAAATTCTTGAATGAGTCCTATAAACATGA ACAGGTTTATATTCGAAGCACAGACGTTGACCGGACTTTGATGAGTGCTATGACAAACCTGGCAGCCCTGTTTCCCCCAGAAGGTGTCAG CATCTGGAATCCTATCCTACTCTGGCAGCCCATCCCGGTGCACACAGTTCCTCTTTCTGAAGATCAGTTGCTATACCTGCCTTTCAGGAA CTGCCCTCGTTTTCAAGAACTTGAGAGTGAGACTTTGAAATCAGAGGAATTCCAGAAGAGGCTGCACCCTTATAAGGATTTTATAGCTAC CTTGGGAAAACTTTCAGGATTACATGGCCAGGACCTTTTTGGAATTTGGAGTAAAGTCTACGACCCTTTATATTGTGAGAGTGTTCACAA TTTCACTTTACCCTCCTGGGCCACTGAGGACACCATGACTAAGTTGAGAGAATTGTCAGAATTGTCCCTCCTGTCCCTCTATGGAATTCA CAAGCAGAAAGAGAAATCTAGGCTCCAAGGGGGTGTCCTGGTCAATGAAATCCTCAATCACATGAAGAGAGCAACTCAGATACCAAGCTA CAAAAAACTCATCATGTATTCTGCGCATGACACTACTGTGAGTGGCCTACAGATGGCGCTAGATGTTTACAACGGACTCCTTCCTCCCTA TGCTTCTTGCCACTTGACGGAATTGTACTTTGAGAAGGGGGAGTACTTTGTGGAGATGTACTATCGGAATGAGACGCAGCACGAGCCGTA TCCCCTCATGCTACCTGGCTGCAGCCCCAGCTGTCCTCTGGAGAGGTTTGCTGAGCTGGTTGGCCCTGTGATCCCTCAAGACTGGTCCAC GGAGTGTATGACCACAAACAGCCATCAAGGTACTGAAGACAGTACAGATTAGTGTGCACAGAGATCTCTGTAGAAGGAGTAGCTGCCCTT TCTCAGGGCAGATGATGCTTTGAGAACATACTTTGGCCATTACCCCCAGCTTTGAGGAAAATGGGCTTTGGATGATTATTTTATGTTTTA GGGACCCCCAACCTCAGGCAATTCCTACCTCTTCACCTGACCCTGCCCCCACTTGCCATAAAACTTAGCTAAGTTTTGTTTTGTTTTTCA GCGTTAATGTAAAGGGGCAGCAGTGCCAAAATATAATCAGAGATAAAGCTTAGGTCAAAGTTCATAGAGTTCCCATGAACTATATGACTG GCCACACAGGATCTTTTGTATTTAAGGATTCTGAGATTTTGCTTGAGCAGGATTAGATAAGGCTGTTCTTTAAATGTCTGAAATGGAACA GATTTCAAAAAAAAACCCCACAATCTAGGATGGGAACAAGGAAGGAAAGATGTGAATAGGCTGATGGGCAAAAAACCAATTTACCCATCA GTTCCAGCCTTCTCTCAAGGAGAGGCAAAGAAAGGAGATACAGTGGAGACATCTGGAAAGTTTTCTCCACTGGAAAACTGCTACTATCTG TTTTTATATTTCTGTTAAAATATATGAGGCTACAGAACTAAAAATTAAAACCTCTTTGTGTCCCTTGGTCCTGGAACATTTATGTTCCTT TTAAAGAAACAAAAATCAAACTTTACAGAAAGATTTGATGTATGTAATACATATAGCAGCTCTTGAAGTATATATATCATAGCAAATAAG TCATCTGATGAGAACAAGCTATTTGGGCACAACACATCAGGAAAGAGAGCACCACGTGATGGAGTTTCTCTAGAAGCTCCAGTGATAAGA GATGTTGACTCTAAAGTTGATTTAAGGCCAGGCATGGTGGTTTACGCCTATAATCCCAGCATTTTGGGAGTCCGAGGTGGGCAGATCACT TGAGCTCAGGAGGTCAAGATCAGCCTGGGCAACATGGTGAAACCTGGTCTCTACATAAAATACAAAAACTTAGATGGGCATGGTGGTGTG TGCCTATAGTCCCACTACTTGTGGGGCTAAGGCAGGAGGATCACTTGAGCCCCGGAGGTCGAGGCTACAGTGAGCCAAGAGTGCACTACT GTACTCCAGCCAGGGCAAGAGAGCGAGACCCTGTCTCAATAAATAAATAAATAAATAAATAAATAAATAAATAAATAAATAAAAACAAAG TTGATTAAGAAAGGAAGTATAGGCCAGGCACAGTGGCTCACACCTGTAATCCTTGCATTTTGGAAGGCTGAGGCAGGAGGATCACTTTAG GCCTGGTGTGTTCAAGACCAGCCTGGTCAACATAGTGAGACACTGTCTCTACCAAAAAAAGGAAGGAAGGGACACATATCAAACTGAAAC AAAATTAGAAATGTAATTATGTTCTAAGTGCCTCCAAGTTCAAAACTTATTGGAATGTTGAGAGTGTGGTTACGAAATACGTTAGGAGGA CAAAAGGAATGTGTAAGTCTTTAATGCCGATATCTTCAGAAAACCTAAGCAAACTTACAGGTCCTGCTGAAACTGCCCACTCTGCAAGAA GAAATCATGATATAGCTTTGCCATGTGGCAGATCTACATGTCTAGAGAACACTGTGCTCTATTACCATTATGGATAAAGATGAGATGGTT TCTAGAGATGGTTTCTACTGGCTGCCAGAATCTAGAGCAAAGCCATCCCCGCTCCTGGTTGGTCACAGAATGACTGACAAAGACATCGAT TGATATGCTTCTTTGTGTTATTTCCCTCCCAAGTAAATGTTTGTCCTTGGGTCCATTTTCTATGCTTGTAACTGTCTTCTAGCAGTGAGC |
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FusionGenePPI for RPLP2_ACPP |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RPLP2 | RPLP1, RPLP2, H2AFX, UBC, ARRB2, SIRT7, CUL3, CUL4A, CUL4B, CUL5, CUL2, CDK2, CUL1, COPS5, COPS6, DCUN1D1, CAND1, NEDD8, RPS11, RPS17, RPS25, RPS26, RPS8, RPL5, RPS7, RPS15A, RPS3A, RPS23, RPL23, RPS4X, RPS24, RPS13, RPS16, RPS5, RPS6, RPS15, RPS2, RPL14, RPS3, RPSA, RPS28, RPS14, RPLP0, RPS20, RPS21, UBA52, HNRNPU, HNRNPA1, RPLP0P6, HNRNPA3, MRPL12, RPS27L, CTNNB1, PA2G4, FN1, UBL4A, PAN2, CD81, IGSF8, ICAM1, MAPK8, YWHAQ, FBXO6, CNDP2, NANS, NPEPPS, AURKA, CEP250, CEP57, TP53, TUBG1, TUBGCP2, TUBGCP4, CUL7, RPL8, DDX24, MRPS21, RPL10, RPL10A, RPL11, RPL12, RPL15, RPL18A, RPL23A, RPL27A, RPL31, RPL35A, RPL37A, RPL7, RPL9, ATP1B2, ATP1B3, COX5B, PABPC1, RPL13A, RPL18, RPL19, RPL21, RPL22, RPL24, RPL26, RPL26L1, RPL27, RPL28, RPL3, RPL30, RPL35, RPL36, RPL38, RPL4, RPL6, RPL7A, RPS10, RPS27, RPS9, SSR3, RPS18, RPS19, LOC101929876, PTEN, EWSR1, SRPK2, MCM2, C3orf17, ZNF746, EGFR, CNBP, RRS1, MAGEB10, SART3, MECP2, RBM34, DGCR8, CYLD, INO80B, TRIM25, BRCA1, HDAC6 | ACPP | ACPP, UBC, SHBG, MMRN1, DDX19B, RPS6KB2, TBC1D22B, FTH1, CDK15, CCDC103, CPLX3, FBXL4, AIRE, ZIC1, DUSP21, IL31RA, FCRL5, KIF3A, NPPA, HSF2, FCF1, LACC1, L2HGDH |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for RPLP2_ACPP |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | ACPP | P15309 | DB06688 | Sipuleucel-T | Prostatic acid phosphatase | biotech | approved|investigational |
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RelatedDiseases for RPLP2_ACPP |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ACPP | C3495559 | Juvenile arthritis | 1 | CTD_human |
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