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Fusion gene ID: 31561 |
FusionGeneSummary for RNF24_ISM1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RNF24_ISM1 | Fusion gene ID: 31561 | Hgene | Tgene | Gene symbol | RNF24 | ISM1 | Gene ID | 11237 | 140862 |
| Gene name | ring finger protein 24 | isthmin 1 | |
| Synonyms | G1L | C20orf82|ISM|Isthmin|bA149I18.1|dJ1077I2.1 | |
| Cytomap | 20p13 | 20p12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | RING finger protein 24 | isthmin-1isthmin 1 homologisthmin 1, angiogenesis inhibitor | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q9Y225 | B1AKI9 | |
| Ensembl transtripts involved in fusion gene | ENST00000336095, ENST00000358395, ENST00000432261, ENST00000545616, | ENST00000262487, | |
| Fusion gene scores | * DoF score | 6 X 4 X 5=120 | 2 X 2 X 2=8 |
| # samples | 6 | 2 | |
| ** MAII score | log2(6/120*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: RNF24 [Title/Abstract] AND ISM1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-AR-A0U3-01A | RNF24 | chr20 | 3925824 | - | ISM1 | chr20 | 13260281 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000336095 | ENST00000262487 | RNF24 | chr20 | 3925824 | - | ISM1 | chr20 | 13260281 | + |
| Frame-shift | ENST00000358395 | ENST00000262487 | RNF24 | chr20 | 3925824 | - | ISM1 | chr20 | 13260281 | + |
| In-frame | ENST00000432261 | ENST00000262487 | RNF24 | chr20 | 3925824 | - | ISM1 | chr20 | 13260281 | + |
| Frame-shift | ENST00000545616 | ENST00000262487 | RNF24 | chr20 | 3925824 | - | ISM1 | chr20 | 13260281 | + |
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FusionProtFeatures for RNF24_ISM1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RNF24 | ISM1 |
| May play a role in TRPCs intracellular trafficking.{ECO:0000269|PubMed:17850865}. | Acts as an angiogenesis inhibitor.{ECO:0000250|UniProtKB:A2ATD1}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | RNF24 | chr20:3925824 | chr20:13260281 | ENST00000336095 | - | 4 | 6 | 24_44 | 76 | 149 | Transmembrane | Helical |
| Hgene | RNF24 | chr20:3925824 | chr20:13260281 | ENST00000358395 | - | 4 | 6 | 24_44 | 76 | 149 | Transmembrane | Helical |
| Hgene | RNF24 | chr20:3925824 | chr20:13260281 | ENST00000432261 | - | 4 | 6 | 24_44 | 97 | 170 | Transmembrane | Helical |
| Hgene | RNF24 | chr20:3925824 | chr20:13260281 | ENST00000545616 | - | 5 | 7 | 24_44 | 97 | 170 | Transmembrane | Helical |
| Tgene | >ISM1 | chr20:3925824 | chr20:13260281 | ENST00000262487 | + | 1 | 6 | 218_262 | 126 | 465 | Domain | TSP type-1 |
| Tgene | >ISM1 | chr20:3925824 | chr20:13260281 | ENST00000262487 | + | 1 | 6 | 289_452 | 126 | 465 | Domain | AMOP |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >RNF24 | chr20:3925824 | chr20:13260281 | ENST00000336095 | - | 4 | 6 | 78_119 | 76 | 149 | Zinc finger | RING-type |
| Hgene | >RNF24 | chr20:3925824 | chr20:13260281 | ENST00000358395 | - | 4 | 6 | 78_119 | 76 | 149 | Zinc finger | RING-type |
| Hgene | >RNF24 | chr20:3925824 | chr20:13260281 | ENST00000432261 | - | 4 | 6 | 78_119 | 97 | 170 | Zinc finger | RING-type |
| Hgene | >RNF24 | chr20:3925824 | chr20:13260281 | ENST00000545616 | - | 5 | 7 | 78_119 | 97 | 170 | Zinc finger | RING-type |
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FusionGeneSequence for RNF24_ISM1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RNF24_ENST00000336095_chr20_3925824_-_ISM1_ENST00000262487_chr20_13260281_+_415aa MSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAYKQVILKEKVKELNLHEVTIEVVDGPDSEAD KDQHPENKPSWSVPSPDWRAWWQRSLSLARANSGDQDYKYDSTSDDSNFLNPPRGWDHTAPGHRTFETKDQPEYDSTDGEGDWSLWSVCS VTCGNGNQKRTRSCGYACTATESRTCDRPNCPGIEDTFRTAATEVSLLAGSEEFNATKLFEVDTDSCERWMSCKSEFLKKYMHKVMNDLP SCPCSYPTEVAYSTADIFDRIKRKDFRWKDASGPKEKLEIYKPTARYCIRSMLSLESTTLAAQHCCYGDNMQLITRGKGAGTPNLISTEF >In-frame_RNF24_ENST00000432261_chr20_3925824_-_ISM1_ENST00000262487_chr20_13260281_+_436aa MLNKSGESRYPALFPVLGGSSMSSDFPHYNFRMPNIGFQNLPLNIYIVVFGTAIFVFILSLLFCCYLIRLRHQAHKEFYAYKQVILKEKV KELNLHEVTIEVVDGPDSEADKDQHPENKPSWSVPSPDWRAWWQRSLSLARANSGDQDYKYDSTSDDSNFLNPPRGWDHTAPGHRTFETK DQPEYDSTDGEGDWSLWSVCSVTCGNGNQKRTRSCGYACTATESRTCDRPNCPGIEDTFRTAATEVSLLAGSEEFNATKLFEVDTDSCER WMSCKSEFLKKYMHKVMNDLPSCPCSYPTEVAYSTADIFDRIKRKDFRWKDASGPKEKLEIYKPTARYCIRSMLSLESTTLAAQHCCYGD |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RNF24_ENST00000336095_chr20_3925824_-_ISM1_ENST00000262487_chr20_13260281_+_1245nt ATGAGCTCGGATTTCCCACATTACAACTTCAGGATGCCTAATATTGGATTCCAGAATCTGCCTCTCAACATATATATTGTGGTTTTTGGT ACTGCTATATTTGTCTTCATCCTTAGTTTACTCTTCTGTTGCTACTTGATTAGGCTAAGACATCAAGCACACAAAGAATTTTATGCCTAC AAACAGGTTATATTAAAAGAGAAAGTAAAAGAATTGAATTTACATGAGGTCACCATAGAGGTGGTCGACGGTCCTGACTCTGAAGCAGAT AAAGATCAGCATCCGGAGAATAAGCCCAGCTGGTCAGTCCCATCCCCCGACTGGCGGGCCTGGTGGCAGAGGTCCCTGTCCTTGGCCAGG GCAAACAGCGGGGACCAGGACTACAAGTACGACAGTACCTCAGACGACAGCAACTTCCTCAACCCCCCCAGGGGGTGGGACCATACAGCC CCAGGCCACCGGACTTTTGAAACCAAAGATCAGCCAGAATATGATTCCACAGATGGCGAGGGTGACTGGAGTCTCTGGTCTGTCTGCAGC GTCACCTGCGGGAACGGCAACCAGAAACGGACCCGGTCTTGTGGCTACGCGTGCACTGCAACAGAATCGAGGACCTGTGACCGTCCAAAC TGCCCAGGAATTGAAGACACTTTTAGGACAGCTGCCACCGAAGTGAGTCTGCTTGCGGGAAGCGAGGAGTTTAATGCCACCAAACTGTTT GAAGTTGACACAGACAGCTGTGAGCGCTGGATGAGCTGCAAAAGCGAGTTCTTAAAGAAGTACATGCACAAGGTGATGAATGACCTGCCC AGCTGCCCCTGCTCCTACCCCACTGAGGTGGCCTACAGCACGGCCGACATCTTCGACCGCATCAAGCGCAAGGACTTCCGCTGGAAGGAC GCCAGCGGGCCCAAGGAGAAGCTGGAGATCTACAAGCCCACTGCCCGGTACTGCATCCGCTCCATGCTGTCCCTGGAGAGCACCACGCTG GCGGCACAGCACTGCTGCTACGGCGACAACATGCAGCTCATCACCAGGGGCAAGGGGGCGGGCACGCCCAACCTCATCAGCACCGAGTTC TCCGCGGAGCTCCACTACAAGGTGGACGTCCTGCCCTGGATTATCTGCAAGGGTGACTGGAGCAGGTATAACGAGGCCCGGCCTCCCAAC >In-frame_RNF24_ENST00000432261_chr20_3925824_-_ISM1_ENST00000262487_chr20_13260281_+_1308nt ATGTTGAATAAGAGTGGTGAGAGCAGATATCCTGCCTTGTTCCCGGTCTTAGGGGGTTCATCCATGAGCTCGGATTTCCCACATTACAAC TTCAGGATGCCTAATATTGGATTCCAGAATCTGCCTCTCAACATATATATTGTGGTTTTTGGTACTGCTATATTTGTCTTCATCCTTAGT TTACTCTTCTGTTGCTACTTGATTAGGCTAAGACATCAAGCACACAAAGAATTTTATGCCTACAAACAGGTTATATTAAAAGAGAAAGTA AAAGAATTGAATTTACATGAGGTCACCATAGAGGTGGTCGACGGTCCTGACTCTGAAGCAGATAAAGATCAGCATCCGGAGAATAAGCCC AGCTGGTCAGTCCCATCCCCCGACTGGCGGGCCTGGTGGCAGAGGTCCCTGTCCTTGGCCAGGGCAAACAGCGGGGACCAGGACTACAAG TACGACAGTACCTCAGACGACAGCAACTTCCTCAACCCCCCCAGGGGGTGGGACCATACAGCCCCAGGCCACCGGACTTTTGAAACCAAA GATCAGCCAGAATATGATTCCACAGATGGCGAGGGTGACTGGAGTCTCTGGTCTGTCTGCAGCGTCACCTGCGGGAACGGCAACCAGAAA CGGACCCGGTCTTGTGGCTACGCGTGCACTGCAACAGAATCGAGGACCTGTGACCGTCCAAACTGCCCAGGAATTGAAGACACTTTTAGG ACAGCTGCCACCGAAGTGAGTCTGCTTGCGGGAAGCGAGGAGTTTAATGCCACCAAACTGTTTGAAGTTGACACAGACAGCTGTGAGCGC TGGATGAGCTGCAAAAGCGAGTTCTTAAAGAAGTACATGCACAAGGTGATGAATGACCTGCCCAGCTGCCCCTGCTCCTACCCCACTGAG GTGGCCTACAGCACGGCCGACATCTTCGACCGCATCAAGCGCAAGGACTTCCGCTGGAAGGACGCCAGCGGGCCCAAGGAGAAGCTGGAG ATCTACAAGCCCACTGCCCGGTACTGCATCCGCTCCATGCTGTCCCTGGAGAGCACCACGCTGGCGGCACAGCACTGCTGCTACGGCGAC AACATGCAGCTCATCACCAGGGGCAAGGGGGCGGGCACGCCCAACCTCATCAGCACCGAGTTCTCCGCGGAGCTCCACTACAAGGTGGAC GTCCTGCCCTGGATTATCTGCAAGGGTGACTGGAGCAGGTATAACGAGGCCCGGCCTCCCAACAACGGACAGAAGTGCACAGAGAGCCCC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RNF24_ENST00000336095_chr20_3925824_-_ISM1_ENST00000262487_chr20_13260281_+_2689nt CTGGGGTTTGGGGGACCGAGCCGCTCCGGGTTCGGGATGCTGAGGAGACCGCGGGCCCGCGCCAGCCTCCCACACACACACACTCTCCCG GCGCCTCGGCCGGCCGGGCGCGGTGTGCAGGGGTGAGGCGGTGTCTCCAGGCTGAGGAGGGACGCGGAGGAGGGTCCGGCGCGGCCCCGG GACTGGAGGGTGAGTCCCTCACAAAGGGCGGAGCGGGGCTGTCACCTGGAGATCACGGAGGGAAGTTCATCCATGAGCTCGGATTTCCCA CATTACAACTTCAGGATGCCTAATATTGGATTCCAGAATCTGCCTCTCAACATATATATTGTGGTTTTTGGTACTGCTATATTTGTCTTC ATCCTTAGTTTACTCTTCTGTTGCTACTTGATTAGGCTAAGACATCAAGCACACAAAGAATTTTATGCCTACAAACAGGTTATATTAAAA GAGAAAGTAAAAGAATTGAATTTACATGAGGTCACCATAGAGGTGGTCGACGGTCCTGACTCTGAAGCAGATAAAGATCAGCATCCGGAG AATAAGCCCAGCTGGTCAGTCCCATCCCCCGACTGGCGGGCCTGGTGGCAGAGGTCCCTGTCCTTGGCCAGGGCAAACAGCGGGGACCAG GACTACAAGTACGACAGTACCTCAGACGACAGCAACTTCCTCAACCCCCCCAGGGGGTGGGACCATACAGCCCCAGGCCACCGGACTTTT GAAACCAAAGATCAGCCAGAATATGATTCCACAGATGGCGAGGGTGACTGGAGTCTCTGGTCTGTCTGCAGCGTCACCTGCGGGAACGGC AACCAGAAACGGACCCGGTCTTGTGGCTACGCGTGCACTGCAACAGAATCGAGGACCTGTGACCGTCCAAACTGCCCAGGAATTGAAGAC ACTTTTAGGACAGCTGCCACCGAAGTGAGTCTGCTTGCGGGAAGCGAGGAGTTTAATGCCACCAAACTGTTTGAAGTTGACACAGACAGC TGTGAGCGCTGGATGAGCTGCAAAAGCGAGTTCTTAAAGAAGTACATGCACAAGGTGATGAATGACCTGCCCAGCTGCCCCTGCTCCTAC CCCACTGAGGTGGCCTACAGCACGGCCGACATCTTCGACCGCATCAAGCGCAAGGACTTCCGCTGGAAGGACGCCAGCGGGCCCAAGGAG AAGCTGGAGATCTACAAGCCCACTGCCCGGTACTGCATCCGCTCCATGCTGTCCCTGGAGAGCACCACGCTGGCGGCACAGCACTGCTGC TACGGCGACAACATGCAGCTCATCACCAGGGGCAAGGGGGCGGGCACGCCCAACCTCATCAGCACCGAGTTCTCCGCGGAGCTCCACTAC AAGGTGGACGTCCTGCCCTGGATTATCTGCAAGGGTGACTGGAGCAGGTATAACGAGGCCCGGCCTCCCAACAACGGACAGAAGTGCACA GAGAGCCCCTCGGACGAGGACTACATCAAGCAGTTCCAAGAGGCCAGGGAATATTAAAGAGACTGGGATGAGGTGGAGGACGCTGCCTCT GGTTCTGGAGCACACACGTGCTGCACTGACGTGCCGACTGGCGCCGAGACCTTCATAGCTGCGGTCGTGTATATTTGTATATACCACATG AGTATTTCTCATACATTACGCTAGGGGCGTGTGCCACGCCCAGGGGACTGCCTTGTGAAGCCGCCCTCGCCATCTGCAGAGCTCCTTGAA AGTGCCCCTGGGGAGCGATGTGGGCAGAAGGATGGGGACAACTTGGAAGCCAGAAGAAGAACCTGGAAGCCACAGTGGGTGCGACTCAAT TCACACCCGGATCCAGAGTTTCAAAGAGAGGCAAAGGGGGAAAGAGACTGAGGTTGTAAACGTTATAAGCAGTTTTTATATATAACTTAT TTAATACAAATGTGACTTAATTAAGCGTAACCTTTTCTCTGGAGTTGTGGTGAAACTAATCACGTCTGTGAGAGATCAGAAAGAAAGAGA CTTAGGGAAGTGGAAGAGAAAGGGAATTTTGGAATTTATTTCTTTAAAAATAATGCAATGGAAATATATCAAAACATGTAAACGCCCACC TTAAACCAAATGTTATTTGGTCATGAGGCACCTTGCTGGAGTCTCAGATTCCAAAAGTCTCTTCTTCAGACTGGGTAGGGAATATGATAT TTTAGGGACAAAGCTGAGGACTGGTTTTAAATAGGCTTTAAAATAAAAGATCAATATTATCATAATGCTATCATTCTGCTAAACGGCCCC AAAACAGTAGAATTTCTGCTCATGTCCTAGCAGGTTCAGAAGACTGCAGCCAAGTTCAGATGTAAAAACAAGAAGTAGCACTTTTCCAAA GGAAAACAACAAAACAAATGGGAAAAAGATAATGGACCGCATTTCACCTATTTTAATACTATTTTAACAATTTTTTCATCTACCAATATA TCCCCAATAAATAAATATAAAAGGGGGGGAGGGTCAATCTGGGGAATCTTAGTTTTTTATGTTTTAAGAAAACAAAAAAAACTGCATTAT TTTTGTAAAGTATTTATTGAGTCACGGATTATTGTGCATCAAGCAATTGTTAATATGACCTGGTCCTATGGGGTAGAACTTAGGAAAAAT >In-frame_RNF24_ENST00000432261_chr20_3925824_-_ISM1_ENST00000262487_chr20_13260281_+_2500nt ATGTTGAATAAGAGTGGTGAGAGCAGATATCCTGCCTTGTTCCCGGTCTTAGGGGGTTCATCCATGAGCTCGGATTTCCCACATTACAAC TTCAGGATGCCTAATATTGGATTCCAGAATCTGCCTCTCAACATATATATTGTGGTTTTTGGTACTGCTATATTTGTCTTCATCCTTAGT TTACTCTTCTGTTGCTACTTGATTAGGCTAAGACATCAAGCACACAAAGAATTTTATGCCTACAAACAGGTTATATTAAAAGAGAAAGTA AAAGAATTGAATTTACATGAGGTCACCATAGAGGTGGTCGACGGTCCTGACTCTGAAGCAGATAAAGATCAGCATCCGGAGAATAAGCCC AGCTGGTCAGTCCCATCCCCCGACTGGCGGGCCTGGTGGCAGAGGTCCCTGTCCTTGGCCAGGGCAAACAGCGGGGACCAGGACTACAAG TACGACAGTACCTCAGACGACAGCAACTTCCTCAACCCCCCCAGGGGGTGGGACCATACAGCCCCAGGCCACCGGACTTTTGAAACCAAA GATCAGCCAGAATATGATTCCACAGATGGCGAGGGTGACTGGAGTCTCTGGTCTGTCTGCAGCGTCACCTGCGGGAACGGCAACCAGAAA CGGACCCGGTCTTGTGGCTACGCGTGCACTGCAACAGAATCGAGGACCTGTGACCGTCCAAACTGCCCAGGAATTGAAGACACTTTTAGG ACAGCTGCCACCGAAGTGAGTCTGCTTGCGGGAAGCGAGGAGTTTAATGCCACCAAACTGTTTGAAGTTGACACAGACAGCTGTGAGCGC TGGATGAGCTGCAAAAGCGAGTTCTTAAAGAAGTACATGCACAAGGTGATGAATGACCTGCCCAGCTGCCCCTGCTCCTACCCCACTGAG GTGGCCTACAGCACGGCCGACATCTTCGACCGCATCAAGCGCAAGGACTTCCGCTGGAAGGACGCCAGCGGGCCCAAGGAGAAGCTGGAG ATCTACAAGCCCACTGCCCGGTACTGCATCCGCTCCATGCTGTCCCTGGAGAGCACCACGCTGGCGGCACAGCACTGCTGCTACGGCGAC AACATGCAGCTCATCACCAGGGGCAAGGGGGCGGGCACGCCCAACCTCATCAGCACCGAGTTCTCCGCGGAGCTCCACTACAAGGTGGAC GTCCTGCCCTGGATTATCTGCAAGGGTGACTGGAGCAGGTATAACGAGGCCCGGCCTCCCAACAACGGACAGAAGTGCACAGAGAGCCCC TCGGACGAGGACTACATCAAGCAGTTCCAAGAGGCCAGGGAATATTAAAGAGACTGGGATGAGGTGGAGGACGCTGCCTCTGGTTCTGGA GCACACACGTGCTGCACTGACGTGCCGACTGGCGCCGAGACCTTCATAGCTGCGGTCGTGTATATTTGTATATACCACATGAGTATTTCT CATACATTACGCTAGGGGCGTGTGCCACGCCCAGGGGACTGCCTTGTGAAGCCGCCCTCGCCATCTGCAGAGCTCCTTGAAAGTGCCCCT GGGGAGCGATGTGGGCAGAAGGATGGGGACAACTTGGAAGCCAGAAGAAGAACCTGGAAGCCACAGTGGGTGCGACTCAATTCACACCCG GATCCAGAGTTTCAAAGAGAGGCAAAGGGGGAAAGAGACTGAGGTTGTAAACGTTATAAGCAGTTTTTATATATAACTTATTTAATACAA ATGTGACTTAATTAAGCGTAACCTTTTCTCTGGAGTTGTGGTGAAACTAATCACGTCTGTGAGAGATCAGAAAGAAAGAGACTTAGGGAA GTGGAAGAGAAAGGGAATTTTGGAATTTATTTCTTTAAAAATAATGCAATGGAAATATATCAAAACATGTAAACGCCCACCTTAAACCAA ATGTTATTTGGTCATGAGGCACCTTGCTGGAGTCTCAGATTCCAAAAGTCTCTTCTTCAGACTGGGTAGGGAATATGATATTTTAGGGAC AAAGCTGAGGACTGGTTTTAAATAGGCTTTAAAATAAAAGATCAATATTATCATAATGCTATCATTCTGCTAAACGGCCCCAAAACAGTA GAATTTCTGCTCATGTCCTAGCAGGTTCAGAAGACTGCAGCCAAGTTCAGATGTAAAAACAAGAAGTAGCACTTTTCCAAAGGAAAACAA CAAAACAAATGGGAAAAAGATAATGGACCGCATTTCACCTATTTTAATACTATTTTAACAATTTTTTCATCTACCAATATATCCCCAATA AATAAATATAAAAGGGGGGGAGGGTCAATCTGGGGAATCTTAGTTTTTTATGTTTTAAGAAAACAAAAAAAACTGCATTATTTTTGTAAA GTATTTATTGAGTCACGGATTATTGTGCATCAAGCAATTGTTAATATGACCTGGTCCTATGGGGTAGAACTTAGGAAAAATAAAGTTGGT |
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FusionGenePPI for RNF24_ISM1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RNF24 | TRPC6, UQCRH | ISM1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for RNF24_ISM1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for RNF24_ISM1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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