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Fusion gene ID: 31466 |
FusionGeneSummary for RNF168_PCYT1A |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RNF168_PCYT1A | Fusion gene ID: 31466 | Hgene | Tgene | Gene symbol | RNF168 | PCYT1A | Gene ID | 165918 | 5130 |
| Gene name | ring finger protein 168 | phosphate cytidylyltransferase 1, choline, alpha | |
| Synonyms | hRNF168 | CCTA|CT|CTA|CTPCT|PCYT1|SMDCRD | |
| Cytomap | 3q29 | 3q29 | |
| Type of gene | protein-coding | protein-coding | |
| Description | E3 ubiquitin-protein ligase RNF168RING-type E3 ubiquitin transferase RNF168ring finger protein 168, E3 ubiquitin protein ligase | choline-phosphate cytidylyltransferase ACCT ACCT-alphaCT ACTP:phosphocholine cytidylyltransferase Aphosphorylcholine transferase A | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q8IYW5 | P49585 | |
| Ensembl transtripts involved in fusion gene | ENST00000318037, | ENST00000419333, ENST00000292823, ENST00000431016, ENST00000491544, | |
| Fusion gene scores | * DoF score | 4 X 3 X 4=48 | 6 X 6 X 5=180 |
| # samples | 5 | 6 | |
| ** MAII score | log2(5/48*10)=0.0588936890535686 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | log2(6/180*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: RNF168 [Title/Abstract] AND PCYT1A [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | RNF168 | GO:0006302 | double-strand break repair | 19203578|19203579|22980979 |
| Hgene | RNF168 | GO:0006511 | ubiquitin-dependent protein catabolic process | 22373579 |
| Hgene | RNF168 | GO:0006974 | cellular response to DNA damage stimulus | 19500350|20550933|22373579|22508508|22980979 |
| Hgene | RNF168 | GO:0010212 | response to ionizing radiation | 19203578|19203579 |
| Hgene | RNF168 | GO:0016567 | protein ubiquitination | 22373579 |
| Hgene | RNF168 | GO:0035518 | histone H2A monoubiquitination | 22980979 |
| Hgene | RNF168 | GO:0036351 | histone H2A-K13 ubiquitination | 22980979 |
| Hgene | RNF168 | GO:0036352 | histone H2A-K15 ubiquitination | 22980979 |
| Hgene | RNF168 | GO:0045739 | positive regulation of DNA repair | 19203578|19203579 |
| Hgene | RNF168 | GO:0070534 | protein K63-linked ubiquitination | 22266820 |
| Hgene | RNF168 | GO:0070535 | histone H2A K63-linked ubiquitination | 19203578|19203579|19500350 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | LGG | TCGA-WY-A859-01A | RNF168 | chr3 | 196229744 | - | PCYT1A | chr3 | 195984758 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000318037 | ENST00000419333 | RNF168 | chr3 | 196229744 | - | PCYT1A | chr3 | 195984758 | - |
| In-frame | ENST00000318037 | ENST00000292823 | RNF168 | chr3 | 196229744 | - | PCYT1A | chr3 | 195984758 | - |
| In-frame | ENST00000318037 | ENST00000431016 | RNF168 | chr3 | 196229744 | - | PCYT1A | chr3 | 195984758 | - |
| 5CDS-5UTR | ENST00000318037 | ENST00000491544 | RNF168 | chr3 | 196229744 | - | PCYT1A | chr3 | 195984758 | - |
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FusionProtFeatures for RNF168_PCYT1A |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RNF168 | PCYT1A |
| E3 ubiquitin-protein ligase required for accumulation ofrepair proteins to sites of DNA damage. Acts with UBE2N/UBC13 toamplify the RNF8-dependent histone ubiquitination. Recruited tosites of DNA damage at double-strand breaks (DSBs) by binding toubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrateubiquitinated histones H2A and H2AX at DNA lesions to thethreshold required for recruitment of TP53BP1 and BRCA1. Alsorecruited at DNA interstrand cross-links (ICLs) sites and promotesaccumulation of 'Lys-63'-linked ubiquitination of histones H2A andH2AX, leading to recruitment of FAAP20/C1orf86 and Fanconi anemia(FA) complex, followed by interstrand cross-link repair. H2Aubiquitination also mediates the ATM-dependent transcriptionalsilencing at regions flanking DSBs in cis, a mechanism to avoidcollision between transcription and repair intermediates. Alsoinvolved in class switch recombination in immune system, via itsrole in regulation of DSBs repair. Following DNA damage, promotesthe ubiquitination and degradation of JMJD2A/KDM4A incollaboration with RNF8, leading to unmask H4K20me2 mark andpromote the recruitment of TP53BP1 at DNA damage sites. Not ableto initiate 'Lys-63'-linked ubiquitination in vitro; possibly dueto partial occlusion of the UBE2N/UBC13-binding region. Catalyzesmonoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histoneH2A (H2AK13Ub and H2AK15Ub, respectively). {ECO:0000255|HAMAP-Rule:MF_03066, ECO:0000269|PubMed:19203578,ECO:0000269|PubMed:19203579, ECO:0000269|PubMed:20550933,ECO:0000269|PubMed:22373579, ECO:0000269|PubMed:22705371,ECO:0000269|PubMed:22713238, ECO:0000269|PubMed:22742833,ECO:0000269|PubMed:22980979, ECO:0000269|PubMed:23760478}. | Controls phosphatidylcholine synthesis. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | RNF168 | chr3:196229744 | chr3:195984758 | ENST00000318037 | - | 1 | 6 | 16_55 | 100 | 572 | Zinc finger | RING-type |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000292823 | - | 2 | 10 | 168_169 | 39 | 368 | Nucleotide binding | CTP |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000292823 | - | 2 | 10 | 196_200 | 39 | 368 | Nucleotide binding | CTP |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000292823 | - | 2 | 10 | 84_92 | 39 | 368 | Nucleotide binding | CTP |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000431016 | - | 1 | 9 | 168_169 | 39 | 368 | Nucleotide binding | CTP |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000431016 | - | 1 | 9 | 196_200 | 39 | 368 | Nucleotide binding | CTP |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000431016 | - | 1 | 9 | 84_92 | 39 | 368 | Nucleotide binding | CTP |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000292823 | - | 2 | 10 | 228_287 | 39 | 368 | Region | Amphipathic |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000292823 | - | 2 | 10 | 256_288 | 39 | 368 | Region | Note=3 X 11 AA approximate tandem repeats |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000292823 | - | 2 | 10 | 319_348 | 39 | 368 | Region | Note=3 X repeats |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000431016 | - | 1 | 9 | 228_287 | 39 | 368 | Region | Amphipathic |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000431016 | - | 1 | 9 | 256_288 | 39 | 368 | Region | Note=3 X 11 AA approximate tandem repeats |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000431016 | - | 1 | 9 | 319_348 | 39 | 368 | Region | Note=3 X repeats |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000292823 | - | 2 | 10 | 319_324 | 39 | 368 | Repeat | Note=1 |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000292823 | - | 2 | 10 | 329_333 | 39 | 368 | Repeat | Note=2%3B approximate |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000292823 | - | 2 | 10 | 343_348 | 39 | 368 | Repeat | Note=3 |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000431016 | - | 1 | 9 | 319_324 | 39 | 368 | Repeat | Note=1 |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000431016 | - | 1 | 9 | 329_333 | 39 | 368 | Repeat | Note=2%3B approximate |
| Tgene | >PCYT1A | chr3:196229744 | chr3:195984758 | ENST00000431016 | - | 1 | 9 | 343_348 | 39 | 368 | Repeat | Note=3 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >RNF168 | chr3:196229744 | chr3:195984758 | ENST00000318037 | - | 1 | 6 | 115_177 | 100 | 572 | Compositional bias | Glu-rich |
| Hgene | >RNF168 | chr3:196229744 | chr3:195984758 | ENST00000318037 | - | 1 | 6 | 110_128 | 100 | 572 | Motif | LR motif 1 |
| Hgene | >RNF168 | chr3:196229744 | chr3:195984758 | ENST00000318037 | - | 1 | 6 | 143_151 | 100 | 572 | Motif | UMI motif |
| Hgene | >RNF168 | chr3:196229744 | chr3:195984758 | ENST00000318037 | - | 1 | 6 | 168_191 | 100 | 572 | Motif | MIU motif 1 |
| Hgene | >RNF168 | chr3:196229744 | chr3:195984758 | ENST00000318037 | - | 1 | 6 | 439_462 | 100 | 572 | Motif | MIU motif 2 |
| Hgene | >RNF168 | chr3:196229744 | chr3:195984758 | ENST00000318037 | - | 1 | 6 | 466_477 | 100 | 572 | Motif | LR motif 2 |
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FusionGeneSequence for RNF168_PCYT1A |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RNF168_ENST00000318037_chr3_196229744_-_PCYT1A_ENST00000419333_chr3_195984758_-_442aa MALPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSLVNVELWTIIQKHYPRECKL RASGQESEEVGLTATSSFFXXNXSXLXXALCQGNYGRSQQRNSLXATCESLCRWNIXLISLWSRPSSDASEEPFPXYVPHCGSLQXXAHT QLQRLHGDEREXALXRSPALPLRGXGGEECALDADTRVPGRTPDXFCSPXXYSLFICWQXXCLXAHQGGRHVCSNTEDRRYLHIRHHHPN CAGLXCVCEAEPAEGLHSKGAQCQLYQREEIPLAGEGXQSKEESERCGGKVKRICSEGGGKKHXPHSEVGGEVPRIHWKFSGNVWSGRST >In-frame_RNF168_ENST00000318037_chr3_196229744_-_PCYT1A_ENST00000292823_chr3_195984758_-_429aa MALPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSLVNVELWTIIQKHYPRECKL RASGQESEEVGLTATSSFFXXNXSXLXXALCQGNYGRSQQRNSLXATCESLCRWNIXLISLWSRPSSDASEEPFPXYVPHCGSLQXXAHT QLQRLHGDEREXALXRSPALPLRGXGGEECALDADTRVPGRTPDXFCSPXXYSLFICWQXXCLXAHQGGRHVCSNTEDRRYLHIRHHHPN CAGLXCVCEAEPAEGLHSKGAQCQLYQREEIPLAGEGXQSKEESERCGGKVKRICSEGGGKKHXPHSEVGGEVPRIHWKFSGNVWSGRST >In-frame_RNF168_ENST00000318037_chr3_196229744_-_PCYT1A_ENST00000431016_chr3_195984758_-_429aa MALPKDAIPSLSECQCGICMEILVEPVTLPCNHTLCKPCFQSTVEKASLCCPFCRRRVSSWTRYHTRRNSLVNVELWTIIQKHYPRECKL RASGQESEEVGLTATSSFFXXNXSXLXXALCQGNYGRSQQRNSLXATCESLCRWNIXLISLWSRPSSDASEEPFPXYVPHCGSLQXXAHT QLQRLHGDEREXALXRSPALPLRGXGGEECALDADTRVPGRTPDXFCSPXXYSLFICWQXXCLXAHQGGRHVCSNTEDRRYLHIRHHHPN CAGLXCVCEAEPAEGLHSKGAQCQLYQREEIPLAGEGXQSKEESERCGGKVKRICSEGGGKKHXPHSEVGGEVPRIHWKFSGNVWSGRST |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RNF168_ENST00000318037_chr3_196229744_-_PCYT1A_ENST00000419333_chr3_195984758_-_1327nt ATGGCTCTACCCAAAGACGCCATCCCCTCGCTGTCCGAGTGCCAGTGCGGGATCTGCATGGAAATCCTCGTGGAGCCCGTCACCCTCCCG TGTAACCACACGCTGTGTAAACCGTGCTTCCAGTCGACCGTCGAAAAGGCGAGTTTATGCTGTCCCTTCTGTCGCCGCCGGGTATCGTCG TGGACTCGGTACCATACCCGAAGAAATTCTCTCGTCAACGTGGAACTGTGGACGATAATTCAAAAACACTATCCCAGGGAGTGCAAGCTT AGAGCGTCTGGCCAAGAATCAGAGGAAGTGGGGCTTACGGCAACCAGCTCCTTTTTCTGATGAAATTGAAGTTGACTTTAGTAAGCCCTA TGTCAGGGTAACTATGGAAGAAGCCAGCAGAGGAACTCCTTGTGAGCGACCTGTGAGAGTTTATGCCGATGGAATATTTGACTTATTTCA CTCTGGTCACGCCCGAGCTCTGATGCAAGCGAAGAACCTTTTCCCTAATACGTACCTCATTGTGGGAGTTTGCAGTGATGAGCTCACACA CAACTTCAAAGGCTTCACGGTGATGAACGAGAATGAGCGCTATGACGCAGTCCAGCACTGCCGCTACGTGGATGAGGTGGTGAGGAATGC GCCCTGGACGCTGACACCCGAGTTCCTGGCCGAACACCGGATTGATTTTGTAGCCCATGATGATATTCCTTATTCATCTGCTGGCAGTGA TGATGTTTATAAGCACATCAAGGAGGCAGGCATGTTTGCTCCAACACAGAGGACAGAAGGTATCTCCACATCAGACATCATCACCCGAAT TGTGCGGGATTATGATGTGTATGCGAGGCGGAACCTGCAGAGGGGCTACACAGCAAAGGAGCTCAATGTCAGCTTTATCAACGAGAAGAA ATACCACTTGCAGGAGAGGGTTGACAAAGTAAAGAAGAAAGTGAAAGATGTGGAGGAAAAGTCAAAAGAATTTGTTCAGAAGGTGGAGGA AAAAAGCATTGACCTCATTCAGAAGTGGGAGGAGAAGTCCCGAGAATTCATTGGAAGTTTTCTGGAAATGTTTGGTCCGGAAGGAGCACT GAAACATATGCTGAAAGAGGGGAAGGGCCGGATGCTGCAGGCCATCAGCCCGAAGCAGAGCCCCAGCAGCAGCCCTACTCGCGAGCGCTC CCCCTCCCCCTCTTTCCGATGGCCCTTCTCCGGCAAGACTTCCCCACCTTGCTCCCCAGCAAATCTCTCCAGGCACAAGGCTGCAGCCTA >In-frame_RNF168_ENST00000318037_chr3_196229744_-_PCYT1A_ENST00000292823_chr3_195984758_-_1288nt ATGGCTCTACCCAAAGACGCCATCCCCTCGCTGTCCGAGTGCCAGTGCGGGATCTGCATGGAAATCCTCGTGGAGCCCGTCACCCTCCCG TGTAACCACACGCTGTGTAAACCGTGCTTCCAGTCGACCGTCGAAAAGGCGAGTTTATGCTGTCCCTTCTGTCGCCGCCGGGTATCGTCG TGGACTCGGTACCATACCCGAAGAAATTCTCTCGTCAACGTGGAACTGTGGACGATAATTCAAAAACACTATCCCAGGGAGTGCAAGCTT AGAGCGTCTGGCCAAGAATCAGAGGAAGTGGGGCTTACGGCAACCAGCTCCTTTTTCTGATGAAATTGAAGTTGACTTTAGTAAGCCCTA TGTCAGGGTAACTATGGAAGAAGCCAGCAGAGGAACTCCTTGTGAGCGACCTGTGAGAGTTTATGCCGATGGAATATTTGACTTATTTCA CTCTGGTCACGCCCGAGCTCTGATGCAAGCGAAGAACCTTTTCCCTAATACGTACCTCATTGTGGGAGTTTGCAGTGATGAGCTCACACA CAACTTCAAAGGCTTCACGGTGATGAACGAGAATGAGCGCTATGACGCAGTCCAGCACTGCCGCTACGTGGATGAGGTGGTGAGGAATGC GCCCTGGACGCTGACACCCGAGTTCCTGGCCGAACACCGGATTGATTTTGTAGCCCATGATGATATTCCTTATTCATCTGCTGGCAGTGA TGATGTTTATAAGCACATCAAGGAGGCAGGCATGTTTGCTCCAACACAGAGGACAGAAGGTATCTCCACATCAGACATCATCACCCGAAT TGTGCGGGATTATGATGTGTATGCGAGGCGGAACCTGCAGAGGGGCTACACAGCAAAGGAGCTCAATGTCAGCTTTATCAACGAGAAGAA ATACCACTTGCAGGAGAGGGTTGACAAAGTAAAGAAGAAAGTGAAAGATGTGGAGGAAAAGTCAAAAGAATTTGTTCAGAAGGTGGAGGA AAAAAGCATTGACCTCATTCAGAAGTGGGAGGAGAAGTCCCGAGAATTCATTGGAAGTTTTCTGGAAATGTTTGGTCCGGAAGGAGCACT GAAACATATGCTGAAAGAGGGGAAGGGCCGGATGCTGCAGGCCATCAGCCCGAAGCAGAGCCCCAGCAGCAGCCCTACTCGCGAGCGCTC CCCCTCCCCCTCTTTCCGATGGCCCTTCTCCGGCAAGACTTCCCCACCTTGCTCCCCAGCAAATCTCTCCAGGCACAAGGCTGCAGCCTA >In-frame_RNF168_ENST00000318037_chr3_196229744_-_PCYT1A_ENST00000431016_chr3_195984758_-_1288nt ATGGCTCTACCCAAAGACGCCATCCCCTCGCTGTCCGAGTGCCAGTGCGGGATCTGCATGGAAATCCTCGTGGAGCCCGTCACCCTCCCG TGTAACCACACGCTGTGTAAACCGTGCTTCCAGTCGACCGTCGAAAAGGCGAGTTTATGCTGTCCCTTCTGTCGCCGCCGGGTATCGTCG TGGACTCGGTACCATACCCGAAGAAATTCTCTCGTCAACGTGGAACTGTGGACGATAATTCAAAAACACTATCCCAGGGAGTGCAAGCTT AGAGCGTCTGGCCAAGAATCAGAGGAAGTGGGGCTTACGGCAACCAGCTCCTTTTTCTGATGAAATTGAAGTTGACTTTAGTAAGCCCTA TGTCAGGGTAACTATGGAAGAAGCCAGCAGAGGAACTCCTTGTGAGCGACCTGTGAGAGTTTATGCCGATGGAATATTTGACTTATTTCA CTCTGGTCACGCCCGAGCTCTGATGCAAGCGAAGAACCTTTTCCCTAATACGTACCTCATTGTGGGAGTTTGCAGTGATGAGCTCACACA CAACTTCAAAGGCTTCACGGTGATGAACGAGAATGAGCGCTATGACGCAGTCCAGCACTGCCGCTACGTGGATGAGGTGGTGAGGAATGC GCCCTGGACGCTGACACCCGAGTTCCTGGCCGAACACCGGATTGATTTTGTAGCCCATGATGATATTCCTTATTCATCTGCTGGCAGTGA TGATGTTTATAAGCACATCAAGGAGGCAGGCATGTTTGCTCCAACACAGAGGACAGAAGGTATCTCCACATCAGACATCATCACCCGAAT TGTGCGGGATTATGATGTGTATGCGAGGCGGAACCTGCAGAGGGGCTACACAGCAAAGGAGCTCAATGTCAGCTTTATCAACGAGAAGAA ATACCACTTGCAGGAGAGGGTTGACAAAGTAAAGAAGAAAGTGAAAGATGTGGAGGAAAAGTCAAAAGAATTTGTTCAGAAGGTGGAGGA AAAAAGCATTGACCTCATTCAGAAGTGGGAGGAGAAGTCCCGAGAATTCATTGGAAGTTTTCTGGAAATGTTTGGTCCGGAAGGAGCACT GAAACATATGCTGAAAGAGGGGAAGGGCCGGATGCTGCAGGCCATCAGCCCGAAGCAGAGCCCCAGCAGCAGCCCTACTCGCGAGCGCTC CCCCTCCCCCTCTTTCCGATGGCCCTTCTCCGGCAAGACTTCCCCACCTTGCTCCCCAGCAAATCTCTCCAGGCACAAGGCTGCAGCCTA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RNF168_ENST00000318037_chr3_196229744_-_PCYT1A_ENST00000419333_chr3_195984758_-_2094nt GCTTGTCCGGTGGCTGCTGCGCTGCCGCAACGAATAGGGTTTCTGGCTGCGTAGGAGGGACGGGGGCGCGGAGCTCTGGGAAACTGCGCC AGGCGCCCGAAAGGTGAACACGGGAGTCGCGCGTCTCCCCCGCAGCAGCGGTAAAGCGGAAGTTATGCTGCAGCCGGAGCCCGGGCTTCC TCCCGGAGCCGCGTCCCGGGGCCCGGCTGCCCCGAGCTGAGCGGAGCATCCTTTCCGGGTGAGGGGAGGAGAGGACTTGGCGCGTTCCCC TCGCTGCCCCGGGAGCCGCAGCCGCGGTGTTCATGCCGCGGAGCAGCCAGGCTCCTCCGACGAAAACCTGCATTTATTTGCTGGCGGGAC GTTTGCCTTGAAAATGGACAAAGACGCCGCCCTCCGGGGTATTCCTGTTTGCCTGACCCTGAGAGCGCCTTTTTGCTTCAAGACGTGTTG GATGCTCCTGTTCTCCGAATTCTGATACGCTTCTGGGCATAATACTGAAACACAAAACTGCTTTTGCTCTCTCTGTGGTTGGCCGAAAAT AGGATTCTTTTTCGTGCAGGTGTCGTTGTTTAGTCGGCTTTACTAACATATTGAAATGGCTCTACCCAAAGACGCCATCCCCTCGCTGTC CGAGTGCCAGTGCGGGATCTGCATGGAAATCCTCGTGGAGCCCGTCACCCTCCCGTGTAACCACACGCTGTGTAAACCGTGCTTCCAGTC GACCGTCGAAAAGGCGAGTTTATGCTGTCCCTTCTGTCGCCGCCGGGTATCGTCGTGGACTCGGTACCATACCCGAAGAAATTCTCTCGT CAACGTGGAACTGTGGACGATAATTCAAAAACACTATCCCAGGGAGTGCAAGCTTAGAGCGTCTGGCCAAGAATCAGAGGAAGTGGGGCT TACGGCAACCAGCTCCTTTTTCTGATGAAATTGAAGTTGACTTTAGTAAGCCCTATGTCAGGGTAACTATGGAAGAAGCCAGCAGAGGAA CTCCTTGTGAGCGACCTGTGAGAGTTTATGCCGATGGAATATTTGACTTATTTCACTCTGGTCACGCCCGAGCTCTGATGCAAGCGAAGA ACCTTTTCCCTAATACGTACCTCATTGTGGGAGTTTGCAGTGATGAGCTCACACACAACTTCAAAGGCTTCACGGTGATGAACGAGAATG AGCGCTATGACGCAGTCCAGCACTGCCGCTACGTGGATGAGGTGGTGAGGAATGCGCCCTGGACGCTGACACCCGAGTTCCTGGCCGAAC ACCGGATTGATTTTGTAGCCCATGATGATATTCCTTATTCATCTGCTGGCAGTGATGATGTTTATAAGCACATCAAGGAGGCAGGCATGT TTGCTCCAACACAGAGGACAGAAGGTATCTCCACATCAGACATCATCACCCGAATTGTGCGGGATTATGATGTGTATGCGAGGCGGAACC TGCAGAGGGGCTACACAGCAAAGGAGCTCAATGTCAGCTTTATCAACGAGAAGAAATACCACTTGCAGGAGAGGGTTGACAAAGTAAAGA AGAAAGTGAAAGATGTGGAGGAAAAGTCAAAAGAATTTGTTCAGAAGGTGGAGGAAAAAAGCATTGACCTCATTCAGAAGTGGGAGGAGA AGTCCCGAGAATTCATTGGAAGTTTTCTGGAAATGTTTGGTCCGGAAGGAGCACTGAAACATATGCTGAAAGAGGGGAAGGGCCGGATGC TGCAGGCCATCAGCCCGAAGCAGAGCCCCAGCAGCAGCCCTACTCGCGAGCGCTCCCCCTCCCCCTCTTTCCGATGGCCCTTCTCCGGCA AGACTTCCCCACCTTGCTCCCCAGCAAATCTCTCCAGGCACAAGGCTGCAGCCTATGATATCAGGTATAGTTACCTGGAACAGAGCAAAT TTGGCTCCCATGTTCTGCTCACCCAGGTGTAGCCTGGCTTGACGGGAAATGATGCCCAGGGTCCAGAGAGCCAGCAGTGTGGACACGCCA AGGAAAGTGTTGATCCATAGAGCTGTGCTCCCCTCAGAAATCTGGTGGCAACAGAAAGTAGTCAGTGAGGCAGGCAAGCTCTCTCTCTCT >In-frame_RNF168_ENST00000318037_chr3_196229744_-_PCYT1A_ENST00000292823_chr3_195984758_-_6203nt GCTTGTCCGGTGGCTGCTGCGCTGCCGCAACGAATAGGGTTTCTGGCTGCGTAGGAGGGACGGGGGCGCGGAGCTCTGGGAAACTGCGCC AGGCGCCCGAAAGGTGAACACGGGAGTCGCGCGTCTCCCCCGCAGCAGCGGTAAAGCGGAAGTTATGCTGCAGCCGGAGCCCGGGCTTCC TCCCGGAGCCGCGTCCCGGGGCCCGGCTGCCCCGAGCTGAGCGGAGCATCCTTTCCGGGTGAGGGGAGGAGAGGACTTGGCGCGTTCCCC TCGCTGCCCCGGGAGCCGCAGCCGCGGTGTTCATGCCGCGGAGCAGCCAGGCTCCTCCGACGAAAACCTGCATTTATTTGCTGGCGGGAC GTTTGCCTTGAAAATGGACAAAGACGCCGCCCTCCGGGGTATTCCTGTTTGCCTGACCCTGAGAGCGCCTTTTTGCTTCAAGACGTGTTG GATGCTCCTGTTCTCCGAATTCTGATACGCTTCTGGGCATAATACTGAAACACAAAACTGCTTTTGCTCTCTCTGTGGTTGGCCGAAAAT AGGATTCTTTTTCGTGCAGGTGTCGTTGTTTAGTCGGCTTTACTAACATATTGAAATGGCTCTACCCAAAGACGCCATCCCCTCGCTGTC CGAGTGCCAGTGCGGGATCTGCATGGAAATCCTCGTGGAGCCCGTCACCCTCCCGTGTAACCACACGCTGTGTAAACCGTGCTTCCAGTC GACCGTCGAAAAGGCGAGTTTATGCTGTCCCTTCTGTCGCCGCCGGGTATCGTCGTGGACTCGGTACCATACCCGAAGAAATTCTCTCGT CAACGTGGAACTGTGGACGATAATTCAAAAACACTATCCCAGGGAGTGCAAGCTTAGAGCGTCTGGCCAAGAATCAGAGGAAGTGGGGCT TACGGCAACCAGCTCCTTTTTCTGATGAAATTGAAGTTGACTTTAGTAAGCCCTATGTCAGGGTAACTATGGAAGAAGCCAGCAGAGGAA CTCCTTGTGAGCGACCTGTGAGAGTTTATGCCGATGGAATATTTGACTTATTTCACTCTGGTCACGCCCGAGCTCTGATGCAAGCGAAGA ACCTTTTCCCTAATACGTACCTCATTGTGGGAGTTTGCAGTGATGAGCTCACACACAACTTCAAAGGCTTCACGGTGATGAACGAGAATG AGCGCTATGACGCAGTCCAGCACTGCCGCTACGTGGATGAGGTGGTGAGGAATGCGCCCTGGACGCTGACACCCGAGTTCCTGGCCGAAC ACCGGATTGATTTTGTAGCCCATGATGATATTCCTTATTCATCTGCTGGCAGTGATGATGTTTATAAGCACATCAAGGAGGCAGGCATGT TTGCTCCAACACAGAGGACAGAAGGTATCTCCACATCAGACATCATCACCCGAATTGTGCGGGATTATGATGTGTATGCGAGGCGGAACC TGCAGAGGGGCTACACAGCAAAGGAGCTCAATGTCAGCTTTATCAACGAGAAGAAATACCACTTGCAGGAGAGGGTTGACAAAGTAAAGA AGAAAGTGAAAGATGTGGAGGAAAAGTCAAAAGAATTTGTTCAGAAGGTGGAGGAAAAAAGCATTGACCTCATTCAGAAGTGGGAGGAGA AGTCCCGAGAATTCATTGGAAGTTTTCTGGAAATGTTTGGTCCGGAAGGAGCACTGAAACATATGCTGAAAGAGGGGAAGGGCCGGATGC TGCAGGCCATCAGCCCGAAGCAGAGCCCCAGCAGCAGCCCTACTCGCGAGCGCTCCCCCTCCCCCTCTTTCCGATGGCCCTTCTCCGGCA AGACTTCCCCACCTTGCTCCCCAGCAAATCTCTCCAGGCACAAGGCTGCAGCCTATGATATCAGTGAGGATGAAGAAGACTAATGTTTCC TCCCTCCTTTCCTGTCCTCCCTTTCTGTCCCATTACCTTCAGAAGCTCTCTGTTGAATTCCAAATTGTGACCCCAACACTAAACCTAAGG ACAGCTACAAAGGAAAGACAACTGGGGAAAGAAGACCTAGGACTGGGGGAACCCAAACAGCCTGTCCTGCAAGTGACATCACTCACCCAC ACGAAGGAGGGGGACTGCACCTTAGAAGCCTGCTCTGCATCCATTTACCCCCCCCCAAGGGCTTTGTTTCACTGTTTATGTTCACGTGAT CTCAACAGGGAAATTGTCATTTTCATTAATTTTTTAAAAAATTCGTCTTTCAAATGTAGAACTAATTTTTTGCCCCTGAGGAGTGGGCAG AAGAAGGAGGTAGTGTAATACGCAGAGGCCTTTTCTTCCCGGTATACTATAGCATTTGCCTTCCGTTCTGAAGCTATGTGGCTTGCCAAG TCCTTCACGAAATGAGCCACGCTGATGGGTAATTTGTGGAGAAATATCTTAATTTTGATTTCCTTAAGGAAAAGCGAAAAGCAGAGTTAC AGTCACAAATCCCCTGAACGTACTGCTGTCACCAGTGTCATTGTGGCTGCGGGAAGGAGATCTGAACCTAACTTTTCTTACTCCCTGAGG AGTTTCTTGTTGGACCCAATGGGGTCCATGAAGACACTGATGGGGATGGAAGCAGACCCATGGCATCAACTGCAGTGTTTCTGCTGTGTT CATCTTCTCAGAAAACTCTGTGACCCAGTTCTTTGGGAGCTTTTGTCAGTCTCTTTCGTGCCATCTACCTTCGAAGGAAGGAACACTTTT AGAGTTACAATGATGAGGAGAGGAGCGGGACAATACTCAATCCTATACCAAGTCGATTGAGATTAGTTTCCTACTGGGAGTAAGTGCCTG GCCCTGCTACTCCTATTTGAATGCTATTAATATTACCTAGCCTTTTACAAAGGATACTTTGTAAATGTCTGCTGTTGGAACTTGATGTTA ATCCATTTTGGTCATAGCCATATTAGAGAGATTTGCACAGAATGTAAAGGCAAAAGCATAGGAAACACCTTCCTTTCTAAAGCAACAGCC TTATCACCTTGACCTCTGTCCCTCTTCAGAACATTCTTCCCTGGAACCAGTGCTCCACATCTTTCTTTTCCTCTGAGAGCTGCAGCTGGC AGGGACCTCCCTCTGCTGCTCCTCCAGCAAGCCACAGAGCATACCCTCACGTGACAAGAGTGTGGTAGGTTTTCTCCCCACTTTTCACAC ACGCCTGGTGGTTGTGGTTCCATCTGCCTTGTTGGCTTGCCCGGGGGGATTCAACACTTGACTTTCAAATCAAAGAATGCTAATGCTTAG CACTTGCTGTTGAGCATGCTCTAACTTTTAAAGCCCTGGCCTCCTGTCTCCTTAGCTGCTTAGCTACGCGGCCTAGCAGATCATCACCCA TCAGTAATCCTGTGGCTAGATCCAGGGGAAAATTGCTTATGTCCAGGCCCCACCCCTGTCACTCATAAATACCCCTTGTGGGGGTGGAAT TTTAGTGTTTTCAGCTAAGAAAACCACATTTTCTCTTTCCTTGCCTCTGCTAGGACTGTGAGCATCTCATAGTCCACTCCCTAAACACTT TCTGGTAACACCTAGTTTTCCGCCTGAGGGTCAGAGGCTAGAATCATTGCCTGCACAGCAGGACTACCTTGGTTCTTAAAACTTGGATCA CCCAGGCAAGGCGTGGTGGCTCACGCCTGTCATCTCAGCACTTTGGGAGACTGAGGCTGGTGGATCACTTGAGGCCACGAGTTTGAGACC AGCCTGACCAACGTGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGGGCACCTGTAATCCCAGCTACTTG GGAGGCTGAGGCAGGAGAATCCCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCAGAGATGGTGCCGCTGCAGTCCAGCCTGGGTGACAG AGCGAGACTCTGTCTCCAAAACAAAACAAAAACCACACACACATACAGAAATAAAGAGAAATAATCAACTAGAAAAAAAACAAAACTTGG ATCACCCAGAAAGAGCGTCACAGAGGCGAGGGAGAATGAAGCCTCTTGTTATCCTGATCGCCTATGACAACGACATTTCTAACTCTTCTT TGAAGCGCAGTTCTTACTCTTAAATCTGGTCATACAAGCTTTGGCTTGGAATCCTGTCTGTCTTTGAAACAGCTGAAGTTAGTGTTTTCC TGTGTTACCCAGTGTTACATAGTCTCATCTTTGAACTTTTCTGCGTCAGCCTTCTCTCTTTGGGAATGCTGCCTGTTTCTGTCTAACTTA TTCTCCCTGGTGTGGTGTGGCAGTGAAGTCTGTGCTGAAGCCCATCTGCTTGGTTCCTCCAAGTGCACATTATGCAAGTGTATTTGGATA GACAGGGAGATGCCCGGAACGTGGTTTTCCTCCTCCCTCCCTATTGGAGCCATACCTCCTAAATATATTGTCTGGGTCCCAAATGTTTGA GCCCTCTTCCTCTGCTCTCAGTGGGCTGCTCTTGGCATGCCCTGTGCTTGGAACGGGACCTGCAGGCTGACAGGCCTCTGAGACTGCTAG GGCCAGCAAACGTACATGTTATTGGGAAACTCCCTTTCCCCTTTTGGTGAGCTTCTACCACCTCAGTCTAATCGTTTTGACTGAAAGCTA TTTGTCTGACTGAAAGCTAAAATCTTTTATAGTGTGGCCTGTTAGATACTTTGGGGTAAATGTGGTCTGAGGTGCTGGACTAGCACGGGT AGATGGAGAAAGCTGTTGGGAAGTTGCATAATGTGGTCATCTGTGCCTAATTAAATGAGGTTAGAGGTGTGCACACCACCACAATGCCTG GGATCTAAATCTTCAGATATTAACGTTTGAGGCTATGGAGCTGTTTCCCTGAATCACACACGAGAAAGCAGTCAACATGGGTGGGCCAAA TGTGGCCAAGATGAGAGAGCCAGAAGTGTTGGCCTTAGAGCAGAGCCTCTGTGTGTGAGACATTAGAAGGCCAGAGCCGGGGAGGTGCCG GCGCAGCCACTGCCTTCCGGTGGGCCGGACGGAAAGCTTGGTCTTATGCTAGATTCAGAAGCACTGAAGAATGGAGGTTGACACTTTAGA GGACTAGGAAGGGATCATTTGTGCTCTTGCAGCTATTGCTGATAGCTAGAGCCAAAGACCATTATATTGCTGAGGCTTGGGTAAGAAAGT TAGGGATGTGAGGAGGTTGAAAATCCTGAAGAAGAGAAAAAATATGAGGGAGGCTAAGGAAACTTAGCCACTTTCTGATCACTGATGACT CCTTAGGCTGCACCTGAGTGATGGTGGTGTTTTTGGAGGCTGTACCTGAGTGATGGTGGTTTTTGGGGGGCTGCACCTGAGCGATAGTGA TTTTTTTTTGGAGGCTGCACAGCTGGTCAGACCATCTCTAGATGTTCTTTCCACAGTGGTTCATAGGGCGTCATTCCCCCTTCCTGGATT ATTTTGACTATGGGTAGCTTATTTTCAAGAGCTCTTTGCCTTTTTAATCCTGTTCCAGATCACTTATCCAAAATCTTTCCAAATCAATTA TATTTTGCTGCTTTTCTTTAATTCCCTAAAAGCCATAGCTTCTAGATTTTCTATCAGCACACATTCTCACCAGAAGTTGAACCAATACAG GTAGAAAAAGAAAGCCCCCTTAATGTTTTTAACTGATGATATTTTTTTAAGCTTACCAATATAAGTATTTTTAAAGGTTCTATTTTTCAA AGTCATAACAATGATTGTTCTTGTTTTCTCTCATAGAATAGACTGCCATCGGATAAAGAGTGGTCCCTAGCTTCTATTTTTCCAAGTAAA TAAGTAGAACATGTTCTTGGGATTATACCATTAAATGTTAATTTTCTTGAAGAAGAAAGATTGTTGTCTGCCAAGATTTTATGTTAGCGC TCGGATTGAGGCAGAAAACGGAAGCACCAGGTTTAACACTGGGATGACTTGGGTTGTGTTCCTGGAGGTTTGAAGTGGGCCTTCCCGCCT TTTGAGGGGGAAAACTGACTGTTTTGAACACATATCCTGGATTAGTTGGGTTGTTTTGTATTGAGGATCCCTAAAAGACAAAAGAGTCTT GGAAAGGACTGCTGGCTTCGTCTTGAACGTTCGCCCCATCACCAGTGTGAGTCCGTGGGGAAGTCTTCCTCAAGTGGGGTTCAGTCTGTA >In-frame_RNF168_ENST00000318037_chr3_196229744_-_PCYT1A_ENST00000431016_chr3_195984758_-_2020nt GCTTGTCCGGTGGCTGCTGCGCTGCCGCAACGAATAGGGTTTCTGGCTGCGTAGGAGGGACGGGGGCGCGGAGCTCTGGGAAACTGCGCC AGGCGCCCGAAAGGTGAACACGGGAGTCGCGCGTCTCCCCCGCAGCAGCGGTAAAGCGGAAGTTATGCTGCAGCCGGAGCCCGGGCTTCC TCCCGGAGCCGCGTCCCGGGGCCCGGCTGCCCCGAGCTGAGCGGAGCATCCTTTCCGGGTGAGGGGAGGAGAGGACTTGGCGCGTTCCCC TCGCTGCCCCGGGAGCCGCAGCCGCGGTGTTCATGCCGCGGAGCAGCCAGGCTCCTCCGACGAAAACCTGCATTTATTTGCTGGCGGGAC GTTTGCCTTGAAAATGGACAAAGACGCCGCCCTCCGGGGTATTCCTGTTTGCCTGACCCTGAGAGCGCCTTTTTGCTTCAAGACGTGTTG GATGCTCCTGTTCTCCGAATTCTGATACGCTTCTGGGCATAATACTGAAACACAAAACTGCTTTTGCTCTCTCTGTGGTTGGCCGAAAAT AGGATTCTTTTTCGTGCAGGTGTCGTTGTTTAGTCGGCTTTACTAACATATTGAAATGGCTCTACCCAAAGACGCCATCCCCTCGCTGTC CGAGTGCCAGTGCGGGATCTGCATGGAAATCCTCGTGGAGCCCGTCACCCTCCCGTGTAACCACACGCTGTGTAAACCGTGCTTCCAGTC GACCGTCGAAAAGGCGAGTTTATGCTGTCCCTTCTGTCGCCGCCGGGTATCGTCGTGGACTCGGTACCATACCCGAAGAAATTCTCTCGT CAACGTGGAACTGTGGACGATAATTCAAAAACACTATCCCAGGGAGTGCAAGCTTAGAGCGTCTGGCCAAGAATCAGAGGAAGTGGGGCT TACGGCAACCAGCTCCTTTTTCTGATGAAATTGAAGTTGACTTTAGTAAGCCCTATGTCAGGGTAACTATGGAAGAAGCCAGCAGAGGAA CTCCTTGTGAGCGACCTGTGAGAGTTTATGCCGATGGAATATTTGACTTATTTCACTCTGGTCACGCCCGAGCTCTGATGCAAGCGAAGA ACCTTTTCCCTAATACGTACCTCATTGTGGGAGTTTGCAGTGATGAGCTCACACACAACTTCAAAGGCTTCACGGTGATGAACGAGAATG AGCGCTATGACGCAGTCCAGCACTGCCGCTACGTGGATGAGGTGGTGAGGAATGCGCCCTGGACGCTGACACCCGAGTTCCTGGCCGAAC ACCGGATTGATTTTGTAGCCCATGATGATATTCCTTATTCATCTGCTGGCAGTGATGATGTTTATAAGCACATCAAGGAGGCAGGCATGT TTGCTCCAACACAGAGGACAGAAGGTATCTCCACATCAGACATCATCACCCGAATTGTGCGGGATTATGATGTGTATGCGAGGCGGAACC TGCAGAGGGGCTACACAGCAAAGGAGCTCAATGTCAGCTTTATCAACGAGAAGAAATACCACTTGCAGGAGAGGGTTGACAAAGTAAAGA AGAAAGTGAAAGATGTGGAGGAAAAGTCAAAAGAATTTGTTCAGAAGGTGGAGGAAAAAAGCATTGACCTCATTCAGAAGTGGGAGGAGA AGTCCCGAGAATTCATTGGAAGTTTTCTGGAAATGTTTGGTCCGGAAGGAGCACTGAAACATATGCTGAAAGAGGGGAAGGGCCGGATGC TGCAGGCCATCAGCCCGAAGCAGAGCCCCAGCAGCAGCCCTACTCGCGAGCGCTCCCCCTCCCCCTCTTTCCGATGGCCCTTCTCCGGCA AGACTTCCCCACCTTGCTCCCCAGCAAATCTCTCCAGGCACAAGGCTGCAGCCTATGATATCAGTGAGGATGAAGAAGACTAATGTTTCC TCCCTCCTTTCCTGTCCTCCCTTTCTGTCCCATTACCTTCAGAAGCTCTCTGTTGAATTCCAAATTGTGACCCCAACACTAAACCTAAGG |
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FusionGenePPI for RNF168_PCYT1A |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RNF168 | UBE2G2, HIST2H2AC, TP53BP1, H2AFX, UBE2N, HIST2H2AA3, HIST2H2BE, HERC2, KDM4A, UBC, KIAA0368, UBE2D3, UBE2E1, DDX1, POC1A, TAF15, EWSR1, DCTN1, KIF5B, SMARCA5, UBR5, TRIP12, LAPTM5, RNF11, KDM1A, JMJD1C, BCL10, RNF168, PSMD11, TBP, SRCAP, CCDC174, NUB1, RPRD1B, TACC3, FAM45A, USP7, SUMO2, SUMO3, HIST1H1C, UBE2D1, H2AFZ, HIST1H2AB, FOXM1, WBP2, PALB2, BRCA2, TOP2A, MKI67, SUMO1, UBB, TJP1, PCM1, PDCD11, NCL, HNRNPM, DDX21, RAI14, LIMA1, DHX9, DHX15, DBN1, PABPC4, USP10 | PCYT1A | BARD1, PDIA6, S100A13, NMNAT1, CEP170, CEP170P1, GPRC5C, IP6K3, TMEM206, STX11 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for RNF168_PCYT1A |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | PCYT1A | P49585 | DB00122 | Choline | Choline-phosphate cytidylyltransferase A | small molecule | approved|nutraceutical |
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RelatedDiseases for RNF168_PCYT1A |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | PCYT1A | C1837073 | Spondylometaphyseal Dysplasia with Cone-Rod Dystrophy | 2 | ORPHANET;UNIPROT |
| Tgene | PCYT1A | C0080178 | Spina Bifida | 1 | CTD_human |
| Tgene | PCYT1A | C4277682 | Chemical and Drug Induced Liver Injury | 1 | CTD_human |
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