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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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Fusion gene ID: 31432

FusionGeneSummary for RNF13_LIMCH1

check button Fusion gene summary
Fusion gene informationFusion gene name: RNF13_LIMCH1
Fusion gene ID: 31432
HgeneTgene
Gene symbol

RNF13

LIMCH1

Gene ID

11342

22998

Gene namering finger protein 13LIM and calponin homology domains 1
SynonymsRZFLIMCH1A|LMO7B
Cytomap

3q25.1

4p13

Type of geneprotein-codingprotein-coding
DescriptionE3 ubiquitin-protein ligase RNF13RING zinc finger proteinRING-type E3 ubiquitin transferase RNF13LIM and calponin homology domains-containing protein 1
Modification date2018052320180519
UniProtAcc

O43567

Q9UPQ0

Ensembl transtripts involved in fusion geneENST00000392894, ENST00000344229, 
ENST00000361785, 		ENST00000513024, 
ENST00000509638, ENST00000508501, 
ENST00000512946, ENST00000313860, 
ENST00000512632, ENST00000512820, 
ENST00000503057, ENST00000511496, 
ENST00000514096, ENST00000509277, 
ENST00000396595, ENST00000381753, 
ENST00000509454, ENST00000515785, 
Fusion gene scores* DoF score3 X 5 X 5=7510 X 10 X 6=600
# samples 610
** MAII scorelog2(6/75*10)=-0.321928094887362
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/600*10)=-2.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RNF13 [Title/Abstract] AND LIMCH1 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1DA317546RNF13chr3

149589944

+LIMCH1chr4

41652408

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000392894ENST00000513024RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000509638RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000508501RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000512946RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000313860RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000512632RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000512820RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000503057RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000511496RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000514096RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000509277RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000396595RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000381753RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000509454RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000392894ENST00000515785RNF13chr3

149589944

+LIMCH1chr4

41652408

+
In-frameENST00000344229ENST00000513024RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000509638RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000508501RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000512946RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000313860RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000512632RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000512820RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000503057RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000511496RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000514096RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000509277RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000396595RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000381753RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000509454RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5CDS-intronENST00000344229ENST00000515785RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-3CDSENST00000361785ENST00000513024RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000509638RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000508501RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000512946RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000313860RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000512632RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000512820RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000503057RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000511496RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000514096RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000509277RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000396595RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000381753RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000509454RNF13chr3

149589944

+LIMCH1chr4

41652408

+
5UTR-intronENST00000361785ENST00000515785RNF13chr3

149589944

+LIMCH1chr4

41652408

+

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FusionProtFeatures for RNF13_LIMCH1


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
RNF13

O43567

LIMCH1

Q9UPQ0

E3 ubiquitin-protein ligase that may play a role incontrolling cell proliferation. {ECO:0000269|PubMed:18794910}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000313860+1127782_8235551084Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000381753+520782_823389891Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000396595+621782_823401903Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000508501+1126782_8235551057Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000511496+823782_823396898Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000512820+1026782_8235431070Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000512946+1126782_8235551058Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000513024+1026782_823384911Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000313860+11271011_10775551084DomainLIM zinc-binding
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000381753+5201011_1077389891DomainLIM zinc-binding
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000396595+6211011_1077401903DomainLIM zinc-binding
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000508501+11261011_10775551057DomainLIM zinc-binding
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000511496+8231011_1077396898DomainLIM zinc-binding
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000512820+10261011_10775431070DomainLIM zinc-binding
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000512946+11261011_10775551058DomainLIM zinc-binding
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000513024+10261011_1077384911DomainLIM zinc-binding

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneRNF13chr3:149589944chr4:41652408ENST00000344229+51165_160107382DomainNote=PA
HgeneRNF13chr3:149589944chr4:41652408ENST00000392894+41065_160107382DomainNote=PA
HgeneRNF13chr3:149589944chr4:41652408ENST00000344229+511204_381107382Topological domainCytoplasmic
HgeneRNF13chr3:149589944chr4:41652408ENST00000344229+51135_182107382Topological domainLumenal
HgeneRNF13chr3:149589944chr4:41652408ENST00000392894+410204_381107382Topological domainCytoplasmic
HgeneRNF13chr3:149589944chr4:41652408ENST00000392894+41035_182107382Topological domainLumenal
HgeneRNF13chr3:149589944chr4:41652408ENST00000344229+511183_203107382TransmembraneHelical
HgeneRNF13chr3:149589944chr4:41652408ENST00000392894+410183_203107382TransmembraneHelical
HgeneRNF13chr3:149589944chr4:41652408ENST00000344229+511240_282107382Zinc fingerRING-type%3B atypical
HgeneRNF13chr3:149589944chr4:41652408ENST00000392894+410240_282107382Zinc fingerRING-type%3B atypical
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000313860+1127354_4395551084Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000381753+520354_439389891Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000396595+621354_439401903Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000508501+1126354_4395551057Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000511496+823354_439396898Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000512820+1026354_4395431070Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000512946+1126354_4395551058Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000513024+1026354_439384911Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000313860+112721_1255551084DomainCalponin-homology (CH)
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000381753+52021_125389891DomainCalponin-homology (CH)
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000396595+62121_125401903DomainCalponin-homology (CH)
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000508501+112621_1255551057DomainCalponin-homology (CH)
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000511496+82321_125396898DomainCalponin-homology (CH)
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000512820+102621_1255431070DomainCalponin-homology (CH)
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000512946+112621_1255551058DomainCalponin-homology (CH)
TgeneLIMCH1chr3:149589944chr4:41652408ENST00000513024+102621_125384911DomainCalponin-homology (CH)


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FusionGeneSequence for RNF13_LIMCH1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).
>In-frame_RNF13_ENST00000392894_chr3_149589944_+_LIMCH1_ENST00000513024_chr4_41652408_+_4382nt
CTCTTTAGTAGGTCGGGTGAGTGTAGTGTGCAGGGAAGAGACGCGTCAGCGCCAGGGCCAGGCCCGCCCGGGGGCAGCCCGGCAGCCGAA
TCTTGGGCTACTCTGTCCCAACAGCCGGAGCAGATCAGACCGACCGGCCCTGCCCGCTCGGTCCCGCGCCCTCCAGACCCTACGGTCTCC
GTTTCTAGGGGCACATGGTTAGCGGCAGGCGCCCACAGCCAATCCACTTTGCCAGCCTGCCCCTTCCTCTGCCAAGAGCAGCTTCTTCAG
CCGCGCTCCAGTTCCGCAGACGCCTGCCCCACCCTGCTCTTCCCTTCCAGGGAAGACGGATCACGCGGCCAAGAACGAGACTCGCAAACT
GGGCATTTCTCCGAGCCGGGCTAGAGCAAGTAGCGAGACTCCGCGTGAGAGTGGGAAAGAGCCTTAACAGGCAACCATGTTGCCCAGTGG
GTTTTCTGTGCCTTTGGGTGCGGACCAATGAGGCGCGTGGGGCGGGACTTCCGCTTCGCCTAGGTGTTGTCGTCCCTGCTAGTACTCCGG
GCTGTGGGGGTCGGTGCGGATATTCAGTCATGAAATCAGGGTAGGGACTTCTCCCGCAGCGACGCGGCTGGCAAGACTGTTTGTGTTGCG
GGGGCCGGACTTCAAGGTGATTTTACAACGAGATGCTGCTCTCCATAGGGATGCTCATGCTGTCAGCCACACAAGTCTACACCATCTTGA
CTGTCCAGCTCTTTGCATTCTTAAACCTACTGCCTGTAGAAGCAGACATTTTAGCATATAACTTTGAAAATGCATCTCAGACATTTGATG
ACCTCCCTGCAAGATTTGGTTATAGACTTCCAGCTGAAGGTTTAAAGGGTTTTTTGATTAACTCAAAACCAGAGAATGCCTGTGAACCCA
TAGTGCCTCCACCAGTAAAAGACAATTCATCTGGCACTTTCATCGTGTTAATTAGAAGACTTGATTGTAATTTTGATATAAAGGTAGACG
GGAAAGTCAGTGTGAATGGAGAGACGGTTCATAGAGAGGAGGAGAAGGAAAGAGAGTGTCCCACGGTGGCACCTGCCCACTCCTTAACCA
AATCCCAGATGTTTGAAGGTGTGGCCAGAGTGCACGGGTCTCCACTGGAGCTGAAACAAGACAACGGTAGCATCGAGATCAACATAAAGA
AGCCAAACTCTGTTCCCCAAGAGCTCGCAGCAACCACTGAGAAAACGGAACCGAATAGTCAAGAGGACAAGAATGATGGTGGAAAATCAA
GAAAAGGGAATATAGAACTTGCCTCATCAGAACCACAGCATTTTACAACAACTGTGACTCGATGCAGCCCGACCGTGGCCTTTGTGGAAT
TTCCCTCCAGCCCCCAGCTGAAGAATGATGTGTCGGAAGAAAAAGACCAGAAGAAACCAGAAAATGAAATGAGTGGAAAGGTGGAGTTGG
TGCTGTCACAAAAGGTGGTAAAGCCAAAATCTCCAGAACCCGAAGCAACGCTGACATTTCCATTTCTGGACAAAATGCCTGAAGCCAACC
AACTACATTTGCCAAATCTCAATTCTCAAGAGTCGCCTGGCACTGCCAGTGTTCCGCTTAGAGTTCAGAACTCTTGGCGACGATCCCAGT
TTTTCTCCCAGTCAGTGGATTCTCCAAGCAGTGAGAAGTCACCTGTTATGACACCTTTTAAGTTCTGGGCATGGGACCCAGAAGAGGAGC
GCAGGCGACAGGAAAAATGGCAACAGGAACAGGAACGTTTGCTCCAGGAGAGATACCAGAAGGAGCAGGACAAGCTGAAAGAAGAGTGGG
AAAAGGCCCAAAAGGAGGTGGAAGAGGAAGAACGCAGATACTATGAGGAGGAGCGTAAGATAATTGAAGACACTGTGGTTCCATTTACTG
TTTCTTCAAGTTCCGCTGACCAGCTGTCTACCTCTTCCTCCATGACTGAAGGCAGTGGGACAATGAATAAGATAGACCTGGGAAACTGTC
AAGATGAAAAACAAGACAGAAGATGGAAGAAATCATTCCAGGGAGATGACAGTGACTTATTGCTGAAGACTAGGGAAAGTGATCGACTGG
AGGAGAAGGGCAGCCTAACTGAAGGGGCCTTGGCTCATTCTGGGAACCCTGTATCAAAAGGAGTCCATGAAGACCATCAGCTGGATACCG
AGGCTGGGGCCCCACACTGTGGAACAAACCCACAGCTTGCTCAGGATCCATCCCAGAATCAGCAGACATCAAATCCAACGCACAGTTCAG
AAGATGTGAAGCCAAAAACCCTCCCGCTGGATAAAAGCATTAACCATCAGATCGAGTCTCCCAGTGAAAGGCGGAAGTCTATAAGTGGAA
AGAAGCTGTGCTCTTCCTGTGGGCTTCCTTTGGGTAAAGGAGCTGCAATGATCATCGAGACCCTCAATCTCTATTTTCACATCCAGTGTT
TCAGGTGTGGAATTTGTAAAGGCCAGCTTGGAGATGCAGTGAGTGGGACGGATGTTAGGATTCGAAATGGTCTCCTGAACTGTAATGATT
GCTACATGCGATCCAGAAGTGCCGGGCAGCCTACAACATTGTGACACGGCTTTCAAGCTTCCGGATCACTCACCATTTCTTTACTGAGAG
TGTCCCCTGGCAACTGCTTAACAAAATCCCAAGCTCAGGGGCTTCTCAGCATTTACCTAATTTCTGAAAGGCTCTTCTGAAAGGTGGTAT
CTGTTCTTTCGTAGCACAGTGTTTATGTTTTTCCTGTTTATTGTTTTGGTTTTTTTTTTTTTTTTGCATTTGCACAGTATACACAAAAGA
ATATGGGGTTGTAATGATCCTGAATAGCTCAAAAAAGGTTTTAGCATGGTCAAACAGGCTTATGGTTTAAAATGTGTTATTCTCTTCTTT
GGGAATTAGCTAAATGATGCAATAAACCTGTTTTGTTTTAGAATGTCTAGGAATTAAACACTTTATGTTTACAGAATTGAGCTGCAGAAA
GTGCAAGACATGCCAATTTGAGACACACGGTCTTCTAAGACTGAAGGATAAATTTAATGCATTTCAGAAACTAAACATCACAGCAAGCTC
TATCTCTGAGCTATAATTTGTTTTTAATGCAAAGACACTAGTTTGATAATATATACTGTAATCCTGAAACATTTGTGTTACTTACCTTTG
GAGGTAGAAATTATACCAATAAATTATTGCACCGTTAGTATTAGATTCTGTGTACCTTGGAAGTTATGTCATTAATATAGGCTGGTTCAT
CAAATAAAGCAAAACCTTGCAATATCAGCTAGATTTACACTCCGGGACGTTGCCCAAAGGTAGGAAGAAAGCAGAGGGAAATATTTCAGT
CATCATTTCCAAAGTCATTATCAAAATCTGTGAGGAAGTTTAATCTTCCAAAGAGTCAATGTCAGACATCAGGCCTCTGTTGCCTGCTTC
TCTCGAGGCACTAGATTAGGAGTCTTCAATAAGAGACTTAACATGAGGTATATGGAAGATGAGGCACCGAGATAAGTTCATCATTAGGTG
TGAGCACTGCTCACCCTTGCTGGCAAGTTCTCCTTAAGGGCCTGAAGCACAGGTGTCCAAAGAAAAGCGTTAAGTCCATCTTAATAGAAT
CTATGTGGTATATGATGTGGTCAGCCCCTGGTCTGTGATCAGCAAGAACCTACAGCACAGATTATGCCCTGCCCACTTCAATGAATACCT
ACTCTCCTCCATTCTCCATCACTTTTTTTGCTATCAAGAACTCCGGACCTTGCCCATGGAGAAGTTTAGAGAGGAACTCTTGTGGAGAGC
TGGTTTATTTTCTGCCCTGTGCGACGAGTTTCAGCTGGCCAAGAAAGGAGTCAAGTTATTAAAAAGCATCACAATGTAGATCTCCAGGCT
GGTTTTTTGTTTTTTGTTGTTAAGACTGGGGAAAGGGGGACTATTTATTCTGCCTTAAATCAATGGCAAATAAGTCAAGATGACATTTTG
TGAATGTAGACTATGGATACACTCCTAATAGATTGATGTAGTCATAAAAGGGGGTCAAGTAGATGTTTTTCTGTTATGTAAGCAATAATT
TTTCCGTGTCTTATTGAGTATGGCTAGCGATTATTTATTACATGCTAGATGGGTTCTTTGCATGTGGGTTCCATATAGGTGCAGAAATTT
CCTCAGCCACTGGAGGGATTTCGACCATATTTGTCATTTGGATGAGCTGTTATTAGATTGAAATCTACACATCATTTCATTAAAAATTGT
GCCTTAGAAAACGCAAAGCTGTTGCACATGGCGATAAATTATGGATGCAGTACATTGAAGAGAGATGAAGTCACTTCCAAGTTTCCAAGA

>In-frame_RNF13_ENST00000344229_chr3_149589944_+_LIMCH1_ENST00000513024_chr4_41652408_+_4422nt
CCCGCCCGGGGGCAGCCCGGCAGCCGAATCTTGGGCTACTCTGTCCCAACAGCCGGAGCAGATCAGACCGACCGGCCCTGCCCGCTCGGT
CCCGCGCCCTCCAGACCCTACGGTCTCCGTTTCTAGGGGCACATGGTTAGCGGCAGGCGCCCACAGCCAATCCACTTTGCCAGCCTGCCC
CTTCCTCTGCCAAGAGCAGCTTCTTCAGCCGCGCTCCAGTTCCGCAGACGCCTGCCCCACCCTGCTCTTCCCTTCCAGGGAAGACGGATC
ACGCGGCCAAGAACGAGACTCGCAAACTGGGCATTTCTCCGAGCCGGGCTAGAGCAAGTAGCGAGACTCCGCGTGAGAGTGGGAAAGAGC
CTTAACAGGCAACCATGTTGCCCAGTGGGTTTTCTGTGCCTTTGGGTGCGGACCAATGAGGCGCGTGGGGCGGGACTTCCGCTTCGCCTA
GGTGTTGTCGTCCCTGCTAGTACTCCGGGCTGTGGGGGTCGGTGCGGATATTCAGTCATGAAATCAGGGTAGGGACTTCTCCCGCAGCGA
CGCGGCTGGCAAGACTGTTTGTGTTGCGGGGGCCGGACTTCAAGAGAGAAAGAGAGAGTGGGCAGACATCGAAGCCAAACAGCAGTATCC
CGGAAGCACTCATGCAACTTTGGTGGCGGCCACTCAGTTTTCTCTGCCAGTGTCTGGTGATTTTACAACGAGATGCTGCTCTCCATAGGG
ATGCTCATGCTGTCAGCCACACAAGTCTACACCATCTTGACTGTCCAGCTCTTTGCATTCTTAAACCTACTGCCTGTAGAAGCAGACATT
TTAGCATATAACTTTGAAAATGCATCTCAGACATTTGATGACCTCCCTGCAAGATTTGGTTATAGACTTCCAGCTGAAGGTTTAAAGGGT
TTTTTGATTAACTCAAAACCAGAGAATGCCTGTGAACCCATAGTGCCTCCACCAGTAAAAGACAATTCATCTGGCACTTTCATCGTGTTA
ATTAGAAGACTTGATTGTAATTTTGATATAAAGGTAGACGGGAAAGTCAGTGTGAATGGAGAGACGGTTCATAGAGAGGAGGAGAAGGAA
AGAGAGTGTCCCACGGTGGCACCTGCCCACTCCTTAACCAAATCCCAGATGTTTGAAGGTGTGGCCAGAGTGCACGGGTCTCCACTGGAG
CTGAAACAAGACAACGGTAGCATCGAGATCAACATAAAGAAGCCAAACTCTGTTCCCCAAGAGCTCGCAGCAACCACTGAGAAAACGGAA
CCGAATAGTCAAGAGGACAAGAATGATGGTGGAAAATCAAGAAAAGGGAATATAGAACTTGCCTCATCAGAACCACAGCATTTTACAACA
ACTGTGACTCGATGCAGCCCGACCGTGGCCTTTGTGGAATTTCCCTCCAGCCCCCAGCTGAAGAATGATGTGTCGGAAGAAAAAGACCAG
AAGAAACCAGAAAATGAAATGAGTGGAAAGGTGGAGTTGGTGCTGTCACAAAAGGTGGTAAAGCCAAAATCTCCAGAACCCGAAGCAACG
CTGACATTTCCATTTCTGGACAAAATGCCTGAAGCCAACCAACTACATTTGCCAAATCTCAATTCTCAAGAGTCGCCTGGCACTGCCAGT
GTTCCGCTTAGAGTTCAGAACTCTTGGCGACGATCCCAGTTTTTCTCCCAGTCAGTGGATTCTCCAAGCAGTGAGAAGTCACCTGTTATG
ACACCTTTTAAGTTCTGGGCATGGGACCCAGAAGAGGAGCGCAGGCGACAGGAAAAATGGCAACAGGAACAGGAACGTTTGCTCCAGGAG
AGATACCAGAAGGAGCAGGACAAGCTGAAAGAAGAGTGGGAAAAGGCCCAAAAGGAGGTGGAAGAGGAAGAACGCAGATACTATGAGGAG
GAGCGTAAGATAATTGAAGACACTGTGGTTCCATTTACTGTTTCTTCAAGTTCCGCTGACCAGCTGTCTACCTCTTCCTCCATGACTGAA
GGCAGTGGGACAATGAATAAGATAGACCTGGGAAACTGTCAAGATGAAAAACAAGACAGAAGATGGAAGAAATCATTCCAGGGAGATGAC
AGTGACTTATTGCTGAAGACTAGGGAAAGTGATCGACTGGAGGAGAAGGGCAGCCTAACTGAAGGGGCCTTGGCTCATTCTGGGAACCCT
GTATCAAAAGGAGTCCATGAAGACCATCAGCTGGATACCGAGGCTGGGGCCCCACACTGTGGAACAAACCCACAGCTTGCTCAGGATCCA
TCCCAGAATCAGCAGACATCAAATCCAACGCACAGTTCAGAAGATGTGAAGCCAAAAACCCTCCCGCTGGATAAAAGCATTAACCATCAG
ATCGAGTCTCCCAGTGAAAGGCGGAAGTCTATAAGTGGAAAGAAGCTGTGCTCTTCCTGTGGGCTTCCTTTGGGTAAAGGAGCTGCAATG
ATCATCGAGACCCTCAATCTCTATTTTCACATCCAGTGTTTCAGGTGTGGAATTTGTAAAGGCCAGCTTGGAGATGCAGTGAGTGGGACG
GATGTTAGGATTCGAAATGGTCTCCTGAACTGTAATGATTGCTACATGCGATCCAGAAGTGCCGGGCAGCCTACAACATTGTGACACGGC
TTTCAAGCTTCCGGATCACTCACCATTTCTTTACTGAGAGTGTCCCCTGGCAACTGCTTAACAAAATCCCAAGCTCAGGGGCTTCTCAGC
ATTTACCTAATTTCTGAAAGGCTCTTCTGAAAGGTGGTATCTGTTCTTTCGTAGCACAGTGTTTATGTTTTTCCTGTTTATTGTTTTGGT
TTTTTTTTTTTTTTTGCATTTGCACAGTATACACAAAAGAATATGGGGTTGTAATGATCCTGAATAGCTCAAAAAAGGTTTTAGCATGGT
CAAACAGGCTTATGGTTTAAAATGTGTTATTCTCTTCTTTGGGAATTAGCTAAATGATGCAATAAACCTGTTTTGTTTTAGAATGTCTAG
GAATTAAACACTTTATGTTTACAGAATTGAGCTGCAGAAAGTGCAAGACATGCCAATTTGAGACACACGGTCTTCTAAGACTGAAGGATA
AATTTAATGCATTTCAGAAACTAAACATCACAGCAAGCTCTATCTCTGAGCTATAATTTGTTTTTAATGCAAAGACACTAGTTTGATAAT
ATATACTGTAATCCTGAAACATTTGTGTTACTTACCTTTGGAGGTAGAAATTATACCAATAAATTATTGCACCGTTAGTATTAGATTCTG
TGTACCTTGGAAGTTATGTCATTAATATAGGCTGGTTCATCAAATAAAGCAAAACCTTGCAATATCAGCTAGATTTACACTCCGGGACGT
TGCCCAAAGGTAGGAAGAAAGCAGAGGGAAATATTTCAGTCATCATTTCCAAAGTCATTATCAAAATCTGTGAGGAAGTTTAATCTTCCA
AAGAGTCAATGTCAGACATCAGGCCTCTGTTGCCTGCTTCTCTCGAGGCACTAGATTAGGAGTCTTCAATAAGAGACTTAACATGAGGTA
TATGGAAGATGAGGCACCGAGATAAGTTCATCATTAGGTGTGAGCACTGCTCACCCTTGCTGGCAAGTTCTCCTTAAGGGCCTGAAGCAC
AGGTGTCCAAAGAAAAGCGTTAAGTCCATCTTAATAGAATCTATGTGGTATATGATGTGGTCAGCCCCTGGTCTGTGATCAGCAAGAACC
TACAGCACAGATTATGCCCTGCCCACTTCAATGAATACCTACTCTCCTCCATTCTCCATCACTTTTTTTGCTATCAAGAACTCCGGACCT
TGCCCATGGAGAAGTTTAGAGAGGAACTCTTGTGGAGAGCTGGTTTATTTTCTGCCCTGTGCGACGAGTTTCAGCTGGCCAAGAAAGGAG
TCAAGTTATTAAAAAGCATCACAATGTAGATCTCCAGGCTGGTTTTTTGTTTTTTGTTGTTAAGACTGGGGAAAGGGGGACTATTTATTC
TGCCTTAAATCAATGGCAAATAAGTCAAGATGACATTTTGTGAATGTAGACTATGGATACACTCCTAATAGATTGATGTAGTCATAAAAG
GGGGTCAAGTAGATGTTTTTCTGTTATGTAAGCAATAATTTTTCCGTGTCTTATTGAGTATGGCTAGCGATTATTTATTACATGCTAGAT
GGGTTCTTTGCATGTGGGTTCCATATAGGTGCAGAAATTTCCTCAGCCACTGGAGGGATTTCGACCATATTTGTCATTTGGATGAGCTGT
TATTAGATTGAAATCTACACATCATTTCATTAAAAATTGTGCCTTAGAAAACGCAAAGCTGTTGCACATGGCGATAAATTATGGATGCAG
TACATTGAAGAGAGATGAAGTCACTTCCAAGTTTCCAAGACTTCTCATGGAGGTGTTTGCTGTTTTACAGGAAAAAATAAAAATAAAAAA


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FusionGenePPI for RNF13_LIMCH1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
RNF13UBE2D1, UBE2D2, UBE2D3, UBE2D4, UBE2E1, UBE2E3, UBE2N, LAMP2, CD63, PGRMC1, LMNB1, SNAPIN, ERN1, NXF1, VTI1B, STX12, LGALS8, LGALS9, AP3S2, AP3D1, HDGFRP3, AP3S1, TYK2, NR2F2, NR2F1, TSPAN3, CLCN7, CLEC11A, STAT5A, NES, MANSC1, RNF167, SPINT2, VIPR1, DCX, AP1S2LIMCH1ELAVL1, SH3KBP1, APP, HUWE1, CUTC, DIABLO, GABPA, KPNA1, NPM1, TRMT61A, RPA3, RPA2, RPA1, OTUD6B, KLHL15, RFC2, YES1, NAGK, GNB4, UNK, NTRK1, CEP120, ODF2, XPO1, CAPZA2, CDK2, MYH9, PPP1CB, IQGAP1, ANLN, MYO19, MYO18A, CDH1, TRIM25


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for RNF13_LIMCH1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for RNF13_LIMCH1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneLIMCH1C0236969Substance-Related Disorders1CTD_human
TgeneLIMCH1C0345967Malignant mesothelioma1CTD_human