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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDrugs

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RelatedDiseases

Fusion gene ID: 31320

FusionGeneSummary for RMI2_CACNA1C

check button Fusion gene summary
Fusion gene informationFusion gene name: RMI2_CACNA1C
Fusion gene ID: 31320
HgeneTgene
Gene symbol

RMI2

CACNA1C

Gene ID

116028

775

Gene nameRecQ mediated genome instability 2calcium voltage-gated channel subunit alpha1 C
SynonymsBLAP18|C16orf75CACH2|CACN2|CACNL1A1|CCHL1A1|CaV1.2|LQT8|TS
Cytomap

16p13.13

12p13.33

Type of geneprotein-codingprotein-coding
DescriptionrecQ-mediated genome instability protein 2BLM-associated protein of 18 kDaRMI2, RecQ mediated genome instability 2, homologvoltage-dependent L-type calcium channel subunit alpha-1CDHPR, alpha-1 subunitcalcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac musclecalcium channel, cardic dihydropyridine-sensitive, alpha-1 subunitcalcium channel, voltage-dependent,
Modification date2018052320180523
UniProtAcc

Q96E14

Q13936

Ensembl transtripts involved in fusion geneENST00000572173, ENST00000572992, 
ENST00000381820, ENST00000312499, 
ENST00000576027, 		ENST00000335762, 
ENST00000399655, ENST00000480911, 
ENST00000399644, ENST00000344100, 
ENST00000399638, ENST00000399629, 
ENST00000399597, ENST00000327702, 
ENST00000399621, ENST00000399649, 
ENST00000399637, ENST00000402845, 
ENST00000399591, ENST00000399641, 
ENST00000347598, ENST00000399606, 
ENST00000399595, ENST00000399601, 
ENST00000399603, ENST00000399634, 
ENST00000399617, ENST00000406454, 
ENST00000491104, 
Fusion gene scores* DoF score8 X 8 X 2=12815 X 14 X 8=1680
# samples 817
** MAII scorelog2(8/128*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1680*10)=-3.30485458152842
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: RMI2 [Title/Abstract] AND CACNA1C [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCACNA1C

GO:0007204

positive regulation of cytosolic calcium ion concentration

12130699

TgeneCACNA1C

GO:0061577

calcium ion transmembrane transport via high voltage-gated calcium channel

15454078

TgeneCACNA1C

GO:0070588

calcium ion transmembrane transport

15454078


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1DB055213RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-intronENST00000572173ENST00000335762RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399655RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000480911RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399644RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000344100RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399638RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399629RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399597RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000327702RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399621RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399649RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399637RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000402845RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399591RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399641RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000347598RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399606RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399595RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399601RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399603RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399634RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000399617RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000406454RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572173ENST00000491104RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000335762RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399655RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000480911RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399644RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000344100RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399638RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399629RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399597RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000327702RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399621RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399649RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399637RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000402845RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399591RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399641RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000347598RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399606RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399595RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399601RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399603RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399634RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000399617RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000406454RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000572992ENST00000491104RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000335762RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399655RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000480911RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399644RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000344100RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399638RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399629RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399597RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000327702RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399621RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399649RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399637RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000402845RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399591RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399641RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000347598RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399606RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399595RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399601RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399603RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399634RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000399617RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000406454RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000381820ENST00000491104RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000335762RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399655RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000480911RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399644RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000344100RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399638RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399629RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399597RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000327702RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399621RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399649RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399637RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000402845RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399591RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399641RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000347598RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399606RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399595RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399601RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399603RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399634RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000399617RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000406454RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000312499ENST00000491104RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000335762RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399655RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000480911RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399644RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000344100RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399638RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399629RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399597RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000327702RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399621RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399649RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399637RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000402845RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399591RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399641RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000347598RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399606RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399595RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399601RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399603RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399634RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000399617RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000406454RMI2chr16

11369741

-CACNA1Cchr12

2394520

+
intron-intronENST00000576027ENST00000491104RMI2chr16

11369741

-CACNA1Cchr12

2394520

+

Top

FusionProtFeatures for RMI2_CACNA1C


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
RMI2

Q96E14

CACNA1C

Q13936

Essential component of the RMI complex, a complex thatplays an important role in the processing of homologousrecombination intermediates. It is required to regulate sisterchromatid segregation and to limit DNA crossover. Essential forthe stability, localization, and function of BLM, TOP3A, andcomplexes containing BLM. In the RMI complex, it is required totarget BLM to chromatin and stress-induced nuclear foci andmitotic phosphorylation of BLM. {ECO:0000269|PubMed:18923082,ECO:0000269|PubMed:18923083, ECO:0000269|PubMed:27977684}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for RMI2_CACNA1C


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

Top

FusionGenePPI for RMI2_CACNA1C


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for RMI2_CACNA1C


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status
TgeneCACNA1CQ13936DB00308IbutilideVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved
TgeneCACNA1CQ13936DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved
TgeneCACNA1CQ13936DB00401NisoldipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved
TgeneCACNA1CQ13936DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved
TgeneCACNA1CQ13936DB00898EthanolVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved
TgeneCACNA1CQ13936DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved
TgeneCACNA1CQ13936DB04855DronedaroneVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved
TgeneCACNA1CQ13936DB09089TrimebutineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved
TgeneCACNA1CQ13936DB09227BarnidipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved
TgeneCACNA1CQ13936DB00270IsradipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB00393NimodipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB00568CinnarizineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB01023FelodipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB01054NitrendipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB04920ClevidipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB06712NilvadipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB06751DrotaverineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB09231BenidipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB09232CilnidipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB09236LacidipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB09238ManidipineVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB11633IsavuconazoleVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational
TgeneCACNA1CQ13936DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|investigational|vet_approved
TgeneCACNA1CQ13936DB01373CalciumVoltage-dependent L-type calcium channel subunit alpha-1Csmall moleculeapproved|nutraceutical

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RelatedDiseases for RMI2_CACNA1C


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
TgeneCACNA1CC0005586Bipolar Disorder8CTD_human;PSYGENET
TgeneCACNA1CC1832916Timothy syndrome6CTD_human;ORPHANET;UNIPROT
TgeneCACNA1CC0011570Mental Depression5PSYGENET
TgeneCACNA1CC0011581Depressive disorder5PSYGENET
TgeneCACNA1CC0041696Unipolar Depression5PSYGENET
TgeneCACNA1CC0525045Mood Disorders5PSYGENET
TgeneCACNA1CC1269683Major Depressive Disorder5PSYGENET
TgeneCACNA1CC0036341Schizophrenia4PSYGENET
TgeneCACNA1CC0033975Psychotic Disorders3PSYGENET
TgeneCACNA1CC0178417Anhedonia2PSYGENET
TgeneCACNA1CC0003811Cardiac Arrhythmia1CTD_human
TgeneCACNA1CC0004352Autistic Disorder1CTD_human
TgeneCACNA1CC0020538Hypertensive disease1CTD_human
TgeneCACNA1CC0020615Hypoglycemia1CTD_human
TgeneCACNA1CC0021051Immunologic Deficiency Syndromes1CTD_human
TgeneCACNA1CC0206762Limb Deformities, Congenital1CTD_human
TgeneCACNA1CC0349204Nonorganic psychosis1PSYGENET
TgeneCACNA1CC2678478Brugada Syndrome 31CTD_human;UNIPROT