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Fusion gene ID: 31037 |
FusionGeneSummary for RFTN1_DAZL |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RFTN1_DAZL | Fusion gene ID: 31037 | Hgene | Tgene | Gene symbol | RFTN1 | DAZL | Gene ID | 23180 | 1618 |
| Gene name | raftlin, lipid raft linker 1 | deleted in azoospermia like | |
| Synonyms | MIG2|PIB10|PIG9|RAFTLIN | DAZH|DAZL1|DAZLA|SPGYLA | |
| Cytomap | 3p24.3 | 3p24.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | raftlincell migration-inducing gene 2 proteinproliferation-inducing protein 10proliferation-inducing protein 9raft-linking protein | deleted in azoospermia-likeDAZ homologDAZ-like autosomalSPGY-like-autosomaldeleted in azoospermia-like 1germline specific RNA binding proteinspermatogenesis gene on the Y-like autosomaltestis secretory sperm-binding protein Li 204a | |
| Modification date | 20180519 | 20180523 | |
| UniProtAcc | Q14699 | Q92904 | |
| Ensembl transtripts involved in fusion gene | ENST00000432519, ENST00000334133, ENST00000483671, | ENST00000250863, ENST00000399444, | |
| Fusion gene scores | * DoF score | 5 X 6 X 5=150 | 3 X 4 X 4=48 |
| # samples | 8 | 6 | |
| ** MAII score | log2(8/150*10)=-0.906890595608519 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/48*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: RFTN1 [Title/Abstract] AND DAZL [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | DAZL | GO:0045948 | positive regulation of translational initiation | 16001084 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | BRCA | TCGA-AO-A128-01A | RFTN1 | chr3 | 16535232 | - | DAZL | chr3 | 16640105 | - |
| TCGA | LD | BRCA | TCGA-BH-A0B9-01A | RFTN1 | chr3 | 16368280 | - | DAZL | chr3 | 16646818 | - |
| TCGA | LD | BRCA | TCGA-BH-A0BZ-01A | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16636090 | - |
| TCGA | RV | LUAD | TCGA-55-6972-01A | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16640105 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| intron-3CDS | ENST00000432519 | ENST00000250863 | RFTN1 | chr3 | 16535232 | - | DAZL | chr3 | 16640105 | - |
| intron-3CDS | ENST00000432519 | ENST00000399444 | RFTN1 | chr3 | 16535232 | - | DAZL | chr3 | 16640105 | - |
| In-frame | ENST00000334133 | ENST00000250863 | RFTN1 | chr3 | 16535232 | - | DAZL | chr3 | 16640105 | - |
| In-frame | ENST00000334133 | ENST00000399444 | RFTN1 | chr3 | 16535232 | - | DAZL | chr3 | 16640105 | - |
| intron-3CDS | ENST00000483671 | ENST00000250863 | RFTN1 | chr3 | 16535232 | - | DAZL | chr3 | 16640105 | - |
| intron-3CDS | ENST00000483671 | ENST00000399444 | RFTN1 | chr3 | 16535232 | - | DAZL | chr3 | 16640105 | - |
| 5CDS-intron | ENST00000432519 | ENST00000250863 | RFTN1 | chr3 | 16368280 | - | DAZL | chr3 | 16646818 | - |
| 5CDS-5UTR | ENST00000432519 | ENST00000399444 | RFTN1 | chr3 | 16368280 | - | DAZL | chr3 | 16646818 | - |
| 5CDS-intron | ENST00000334133 | ENST00000250863 | RFTN1 | chr3 | 16368280 | - | DAZL | chr3 | 16646818 | - |
| 5CDS-5UTR | ENST00000334133 | ENST00000399444 | RFTN1 | chr3 | 16368280 | - | DAZL | chr3 | 16646818 | - |
| 5UTR-intron | ENST00000483671 | ENST00000250863 | RFTN1 | chr3 | 16368280 | - | DAZL | chr3 | 16646818 | - |
| 5UTR-5UTR | ENST00000483671 | ENST00000399444 | RFTN1 | chr3 | 16368280 | - | DAZL | chr3 | 16646818 | - |
| In-frame | ENST00000432519 | ENST00000250863 | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16636090 | - |
| In-frame | ENST00000432519 | ENST00000399444 | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16636090 | - |
| Frame-shift | ENST00000334133 | ENST00000250863 | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16636090 | - |
| Frame-shift | ENST00000334133 | ENST00000399444 | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16636090 | - |
| intron-3CDS | ENST00000483671 | ENST00000250863 | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16636090 | - |
| intron-3CDS | ENST00000483671 | ENST00000399444 | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16636090 | - |
| In-frame | ENST00000432519 | ENST00000250863 | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16640105 | - |
| In-frame | ENST00000432519 | ENST00000399444 | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16640105 | - |
| Frame-shift | ENST00000334133 | ENST00000250863 | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16640105 | - |
| Frame-shift | ENST00000334133 | ENST00000399444 | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16640105 | - |
| intron-3CDS | ENST00000483671 | ENST00000250863 | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16640105 | - |
| intron-3CDS | ENST00000483671 | ENST00000399444 | RFTN1 | chr3 | 16450882 | - | DAZL | chr3 | 16640105 | - |
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FusionProtFeatures for RFTN1_DAZL |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RFTN1 | DAZL |
| Involved in protein trafficking via association withclathrin and AP2 complex (PubMed:27022195, PubMed:21266579). Uponbacterial lipopolysaccharide stimulation, mediates internalizationof TLR4 to endosomes in dendritic cells and macrophages; andinternalization of poly(I:C) to TLR3-positive endosomes in myeloiddendritic cells and epithelial cells; resulting in activation ofTICAM1-mediated signaling and subsequent IFNB1 production(PubMed:27022195, PubMed:21266579). Involved in T-cell antigenreceptor-mediated signaling by regulating tyrosine kinase LCKlocalization, T-cell dependent antibody production and cytokinesecretion (By similarity). May regulate B-cell antigen receptor-mediated signaling (PubMed:12805216). May play a pivotal role inthe formation and/or maintenance of lipid rafts (PubMed:12805216).{ECO:0000250|UniProtKB:Q6A0D4, ECO:0000269|PubMed:12805216,ECO:0000269|PubMed:21266579, ECO:0000269|PubMed:27022195}. | RNA-binding protein, which is essential forgametogenesis in both males and females. Plays a central roleduring spermatogenesis. Acts by binding to the 3'-UTR of mRNA,specifically recognizing GUU triplets, and thereby regulating thetranslation of key transcripts (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | >DAZL | chr3:16450882 | chr3:16640105 | ENST00000250863 | - | 0 | 11 | 167_190 | 21 | 316 | Domain | Note=DAZ-like |
| Tgene | >DAZL | chr3:16450882 | chr3:16640105 | ENST00000250863 | - | 0 | 11 | 40_115 | 21 | 316 | Domain | RRM |
| Tgene | >DAZL | chr3:16450882 | chr3:16640105 | ENST00000399444 | - | 0 | 11 | 167_190 | 1 | 296 | Domain | Note=DAZ-like |
| Tgene | >DAZL | chr3:16450882 | chr3:16640105 | ENST00000399444 | - | 0 | 11 | 40_115 | 1 | 296 | Domain | RRM |
| Tgene | >DAZL | chr3:16450882 | chr3:16640105 | ENST00000250863 | - | 0 | 11 | 80_132 | 21 | 316 | Region | Homodimerization |
| Tgene | >DAZL | chr3:16450882 | chr3:16640105 | ENST00000399444 | - | 0 | 11 | 80_132 | 1 | 296 | Region | Homodimerization |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | DAZL | chr3:16450882 | chr3:16636090 | ENST00000250863 | - | 6 | 11 | 167_190 | 210 | 316 | Domain | Note=DAZ-like |
| Tgene | DAZL | chr3:16450882 | chr3:16636090 | ENST00000250863 | - | 6 | 11 | 40_115 | 210 | 316 | Domain | RRM |
| Tgene | DAZL | chr3:16450882 | chr3:16636090 | ENST00000399444 | - | 6 | 11 | 167_190 | 190 | 296 | Domain | Note=DAZ-like |
| Tgene | DAZL | chr3:16450882 | chr3:16636090 | ENST00000399444 | - | 6 | 11 | 40_115 | 190 | 296 | Domain | RRM |
| Tgene | DAZL | chr3:16450882 | chr3:16636090 | ENST00000250863 | - | 6 | 11 | 80_132 | 210 | 316 | Region | Homodimerization |
| Tgene | DAZL | chr3:16450882 | chr3:16636090 | ENST00000399444 | - | 6 | 11 | 80_132 | 190 | 296 | Region | Homodimerization |
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FusionGeneSequence for RFTN1_DAZL |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RFTN1_ENST00000334133_chr3_16535232_-_DAZL_ENST00000250863_chr3_16640105_-_343aa MGCGLNKLEKRDEKRPGNIYSTLKRPQVETKIDVSYEYRFLEFTTLSAVYCKSXNSKLNHLQRGQHPVLISCNQPRLYFTRRQNHAKHCF CWRNXCXDGXNXDXKLLCXIWFSERSEDNHXSNWCVQRLWICFIFXXRGCAEDSRITDKFPWXKAEAGPCNQETKFMCLSCAATSFGFXS SSSTTVSECLDXSKHXNLYAAHNHDESYNSVCSGISYLPKFTSSGHHWISVACIXLSDATTVACWGAKELCCTSGLFSCXLPLXXSXSRS >In-frame_RFTN1_ENST00000334133_chr3_16535232_-_DAZL_ENST00000399444_chr3_16640105_-_343aa MGCGLNKLEKRDEKRPGNIYSTLKRPQVETKIDVSYEYRFLEFTTLSAVYCKSXNSKLNHLQRGQHPVLISCNQPRLYFTRRQNHAKHCF CWRNXCXDGXNXDXKLLCXIWFSERSEDNHXSNWCVQRLWICFIFXXRGCAEDSRITDKFPWXKAEAGPCNQETKFMCLSCAATSFGFXS SSSTTVSECLDXSKHXNLYAAHNHDESYNSVCSGISYLPKFTSSGHHWISVACIXLSDATTVACWGAKELCCTSGLFSCXLPLXXSXSRS >In-frame_RFTN1_ENST00000432519_chr3_16450882_-_DAZL_ENST00000250863_chr3_16636090_-_217aa MYCDGAVDLDAAAELPGSSAVRLASLRDLPAQLLELYQQGFSLAALHPFVQPTHEREKTPLEHIFRAILIKKTDRSQKTDLHNEGYILEL DCCSSLDHPTDQKLIPEFIKKMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCL >In-frame_RFTN1_ENST00000432519_chr3_16450882_-_DAZL_ENST00000399444_chr3_16636090_-_217aa MYCDGAVDLDAAAELPGSSAVRLASLRDLPAQLLELYQQGFSLAALHPFVQPTHEREKTPLEHIFRAILIKKTDRSQKTDLHNEGYILEL DCCSSLDHPTDQKLIPEFIKKMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDRSIQTVVSCL >In-frame_RFTN1_ENST00000432519_chr3_16450882_-_DAZL_ENST00000250863_chr3_16640105_-_406aa MYCDGAVDLDAAAELPGSSAVRLASLRDLPAQLLELYQQGFSLAALHPFVQPTHEREKTPLEHIFRAILIKKTDRSQKTDLHNEGYILEL DCCSSLDHPTDQKLIPEFIKKSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVK IITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNP ITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDR >In-frame_RFTN1_ENST00000432519_chr3_16450882_-_DAZL_ENST00000399444_chr3_16640105_-_406aa MYCDGAVDLDAAAELPGSSAVRLASLRDLPAQLLELYQQGFSLAALHPFVQPTHEREKTPLEHIFRAILIKKTDRSQKTDLHNEGYILEL DCCSSLDHPTDQKLIPEFIKKSTANPETPNSTISREASTQSSSAATSQGYILPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVK IITDRTGVSKGYGFVSFFNDVDVQKIVESQINFHGKKLKLGPAIRKQNLCAYHVQPRPLVFNHPPPPQFQNVWTNPNTETYMQPTTTMNP ITQYVQAYPTYPNSPVQVITGYQLPVYNYQMPPQWPVGEQRSYVVPPAYSAVNYHCNEVDPGAEVVPNECSVHEATPPSGNGPQKKSVDR |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RFTN1_ENST00000334133_chr3_16535232_-_DAZL_ENST00000250863_chr3_16640105_-_1030nt ATGGGTTGCGGATTGAACAAGTTAGAGAAACGTGATGAAAAACGGCCTGGGAATATTTATTCAACTTTGAAGAGGCCTCAGGTGGAAACC AAGATAGATGTGTCCTATGAATACCGCTTCCTGGAGTTCACGACTCTGAGTGCTGTCTACTGCAAATCCTGAAACTCCAAACTCAACCAT CTCCAGAGAGGCCAGCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAACACTGTTTT TGTTGGAGGAATTGATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAGATAATCAC TGATCGAACTGGTGTGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAGATAAATTT CCATGGTAAAAAGCTGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTTTTTAATCA TCCTCCTCCACCACAGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCTATAACTCA GTATGTTCAGGCATATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAGATGCCACC ACAGTGGCCTGTTGGGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAGC TGAAGTTGTGCCAAATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATACA AACGGTGGTATCTTGTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGCA >In-frame_RFTN1_ENST00000334133_chr3_16535232_-_DAZL_ENST00000399444_chr3_16640105_-_1030nt ATGGGTTGCGGATTGAACAAGTTAGAGAAACGTGATGAAAAACGGCCTGGGAATATTTATTCAACTTTGAAGAGGCCTCAGGTGGAAACC AAGATAGATGTGTCCTATGAATACCGCTTCCTGGAGTTCACGACTCTGAGTGCTGTCTACTGCAAATCCTGAAACTCCAAACTCAACCAT CTCCAGAGAGGCCAGCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAACACTGTTTT TGTTGGAGGAATTGATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAGATAATCAC TGATCGAACTGGTGTGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAGATAAATTT CCATGGTAAAAAGCTGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTTTTTAATCA TCCTCCTCCACCACAGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCTATAACTCA GTATGTTCAGGCATATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAGATGCCACC ACAGTGGCCTGTTGGGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAGC TGAAGTTGTGCCAAATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATACA AACGGTGGTATCTTGTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGCA >In-frame_RFTN1_ENST00000432519_chr3_16450882_-_DAZL_ENST00000250863_chr3_16636090_-_651nt ATGTATTGTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCC GCCCAGCTCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCC CTGGAGCACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTA GATTGCTGTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGATGCCACCACAGTGGCCTGTTGGGGAG CAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAGCTGAAGTTGTGCCAAATGAA TGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATACAAACGGTGGTATCTTGTCTG TTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGCATCACTTTAGAAGAAGTCGG >In-frame_RFTN1_ENST00000432519_chr3_16450882_-_DAZL_ENST00000399444_chr3_16636090_-_651nt ATGTATTGTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCC GCCCAGCTCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCC CTGGAGCACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTA GATTGCTGTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGATGCCACCACAGTGGCCTGTTGGGGAG CAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAGCTGAAGTTGTGCCAAATGAA TGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATACAAACGGTGGTATCTTGTCTG TTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGCATCACTTTAGAAGAAGTCGG >In-frame_RFTN1_ENST00000432519_chr3_16450882_-_DAZL_ENST00000250863_chr3_16640105_-_1218nt ATGTATTGTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCC GCCCAGCTCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCC CTGGAGCACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTA GATTGCTGTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGTCTACTGCAAATCCTGAAACTCCAAAC TCAACCATCTCCAGAGAGGCCAGCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAAC ACTGTTTTTGTTGGAGGAATTGATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAG ATAATCACTGATCGAACTGGTGTGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAG ATAAATTTCCATGGTAAAAAGCTGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTT TTTAATCATCCTCCTCCACCACAGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCT ATAACTCAGTATGTTCAGGCATATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAG ATGCCACCACAGTGGCCTGTTGGGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGAT CCAGGAGCTGAAGTTGTGCCAAATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGA AGCATACAAACGGTGGTATCTTGTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAA >In-frame_RFTN1_ENST00000432519_chr3_16450882_-_DAZL_ENST00000399444_chr3_16640105_-_1218nt ATGTATTGTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCC GCCCAGCTCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCC CTGGAGCACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTA GATTGCTGTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGTCTACTGCAAATCCTGAAACTCCAAAC TCAACCATCTCCAGAGAGGCCAGCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAAC ACTGTTTTTGTTGGAGGAATTGATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAG ATAATCACTGATCGAACTGGTGTGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAG ATAAATTTCCATGGTAAAAAGCTGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTT TTTAATCATCCTCCTCCACCACAGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCT ATAACTCAGTATGTTCAGGCATATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAG ATGCCACCACAGTGGCCTGTTGGGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGAT CCAGGAGCTGAAGTTGTGCCAAATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGA AGCATACAAACGGTGGTATCTTGTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RFTN1_ENST00000334133_chr3_16535232_-_DAZL_ENST00000250863_chr3_16640105_-_3171nt CGTCGGGGCTGGAGCCGGAGCGCGCCGGGCGCTGGGCGCAGCGAGCGAGAGCGCGGCGGCCGCGGGCTCCGGCGAGGGACAGACGCACCG ATCGCCGGAGGGACAGACACACGACCACGCGGCGCCACCGCCCACGCCTCCACCCACCGGCGCCCAAGTCCTCCCCGCGCCGCCTCCTCT GTATGGCACAAACTTTCCTCCCGGGACGGAACACGCTGCCTCAGGGAGCCCGCGACCGCGCCTTCTCCTCCGCCGGTCCCATACGCTGCT GAAATGGGTTGCGGATTGAACAAGTTAGAGAAACGTGATGAAAAACGGCCTGGGAATATTTATTCAACTTTGAAGAGGCCTCAGGTGGAA ACCAAGATAGATGTGTCCTATGAATACCGCTTCCTGGAGTTCACGACTCTGAGTGCTGTCTACTGCAAATCCTGAAACTCCAAACTCAAC CATCTCCAGAGAGGCCAGCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAACACTGT TTTTGTTGGAGGAATTGATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAGATAAT CACTGATCGAACTGGTGTGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAGATAAA TTTCCATGGTAAAAAGCTGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTTTTTAA TCATCCTCCTCCACCACAGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCTATAAC TCAGTATGTTCAGGCATATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAGATGCC ACCACAGTGGCCTGTTGGGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGG AGCTGAAGTTGTGCCAAATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCAT ACAAACGGTGGTATCTTGTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGT GCATCACTTTAGAAGAAGTCGGGCAATGCTTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATAT TAAGCTAAAAGGTTTCCACTATTATAGAAATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCT AGTTTTATCTTAAACTGTTCTTCATTAGATGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGAC TGAAAGAAACTAAGATTTATCTGCAAGGATTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTT TTAAAAACCTATTTTGAAAGGTCAGAATTTTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATT TACAGTATTGAGCTTTGCATTTATGATTTCTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCA ATATATAGTTAGCTTTATTGAAGTCTTCTTATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTAT TCAAAATATTTTATCTTTTAGCTAGAATCCACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAA TTTTTTAAAGAATCCAAGACAAACTAAACTTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTT CTTTGAAATGCTAAACTTGGCTGTATGTCAAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTA ATCAGAGTATCTGAAGGGAATTGTTTTTATAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTT GTAAAGTAAAATATGTCCAGAAGAGTCAAAGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAAT GTGCTAGAGTTAAAAGTTAGCATTGTTTCTAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTT GCTATACCACAGTCTTTCGTTTCCAGCCTTTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGC TGTATGAGCAGAGCAGTTCAAGGGCCAAACCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCA TTTGATCTGCCATGGACATGAGTTTAAAGCGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATG TAGTTACTGTGAGCCATATTACTAGTGCCCCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAAC TTTAGAATTCCCAAGAGGGCTTTATTACACCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGT GCTATAACATTCTGACACATATCATTCTGTGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTAT TCCAATATGACCTTAAGGAAAAGTAAGGGAATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAG TCCTGAACCTTTCAAAATGGAAAATTAATTCTAAACTTAGAAATATGCTTCTGCCTATTGCTGATACTGTCTTTGCATACATGAATAAAA >In-frame_RFTN1_ENST00000334133_chr3_16535232_-_DAZL_ENST00000399444_chr3_16640105_-_3171nt CGTCGGGGCTGGAGCCGGAGCGCGCCGGGCGCTGGGCGCAGCGAGCGAGAGCGCGGCGGCCGCGGGCTCCGGCGAGGGACAGACGCACCG ATCGCCGGAGGGACAGACACACGACCACGCGGCGCCACCGCCCACGCCTCCACCCACCGGCGCCCAAGTCCTCCCCGCGCCGCCTCCTCT GTATGGCACAAACTTTCCTCCCGGGACGGAACACGCTGCCTCAGGGAGCCCGCGACCGCGCCTTCTCCTCCGCCGGTCCCATACGCTGCT GAAATGGGTTGCGGATTGAACAAGTTAGAGAAACGTGATGAAAAACGGCCTGGGAATATTTATTCAACTTTGAAGAGGCCTCAGGTGGAA ACCAAGATAGATGTGTCCTATGAATACCGCTTCCTGGAGTTCACGACTCTGAGTGCTGTCTACTGCAAATCCTGAAACTCCAAACTCAAC CATCTCCAGAGAGGCCAGCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAACACTGT TTTTGTTGGAGGAATTGATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAGATAAT CACTGATCGAACTGGTGTGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAGATAAA TTTCCATGGTAAAAAGCTGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTTTTTAA TCATCCTCCTCCACCACAGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCTATAAC TCAGTATGTTCAGGCATATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAGATGCC ACCACAGTGGCCTGTTGGGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGG AGCTGAAGTTGTGCCAAATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCAT ACAAACGGTGGTATCTTGTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGT GCATCACTTTAGAAGAAGTCGGGCAATGCTTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATAT TAAGCTAAAAGGTTTCCACTATTATAGAAATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCT AGTTTTATCTTAAACTGTTCTTCATTAGATGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGAC TGAAAGAAACTAAGATTTATCTGCAAGGATTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTT TTAAAAACCTATTTTGAAAGGTCAGAATTTTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATT TACAGTATTGAGCTTTGCATTTATGATTTCTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCA ATATATAGTTAGCTTTATTGAAGTCTTCTTATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTAT TCAAAATATTTTATCTTTTAGCTAGAATCCACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAA TTTTTTAAAGAATCCAAGACAAACTAAACTTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTT CTTTGAAATGCTAAACTTGGCTGTATGTCAAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTA ATCAGAGTATCTGAAGGGAATTGTTTTTATAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTT GTAAAGTAAAATATGTCCAGAAGAGTCAAAGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAAT GTGCTAGAGTTAAAAGTTAGCATTGTTTCTAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTT GCTATACCACAGTCTTTCGTTTCCAGCCTTTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGC TGTATGAGCAGAGCAGTTCAAGGGCCAAACCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCA TTTGATCTGCCATGGACATGAGTTTAAAGCGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATG TAGTTACTGTGAGCCATATTACTAGTGCCCCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAAC TTTAGAATTCCCAAGAGGGCTTTATTACACCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGT GCTATAACATTCTGACACATATCATTCTGTGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTAT TCCAATATGACCTTAAGGAAAAGTAAGGGAATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAG TCCTGAACCTTTCAAAATGGAAAATTAATTCTAAACTTAGAAATATGCTTCTGCCTATTGCTGATACTGTCTTTGCATACATGAATAAAA >In-frame_RFTN1_ENST00000432519_chr3_16450882_-_DAZL_ENST00000250863_chr3_16636090_-_2602nt CTCGTACAGTCCTTCATCTTCATGGCAGAAAGGCTGTTCTGCCCCTGCGCCCTCCCTGGCCTCTCTGGGGATCCCTGCAGCTGATGTATT GTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCCGCCCAGC TCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCCCTGGAGC ACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTAGATTGCT GTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGATGCCACCACAGTGGCCTGTTGGGGAGCAAAGGA GCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAGCTGAAGTTGTGCCAAATGAATGTTCAG TTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATACAAACGGTGGTATCTTGTCTGTTTAATC CAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGCATCACTTTAGAAGAAGTCGGGCAATGC TTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATATTAAGCTAAAAGGTTTCCACTATTATAGAA ATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCTAGTTTTATCTTAAACTGTTCTTCATTAGA TGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGACTGAAAGAAACTAAGATTTATCTGCAAGGA TTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTTTTAAAAACCTATTTTGAAAGGTCAGAATT TTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATTTACAGTATTGAGCTTTGCATTTATGATTT CTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCAATATATAGTTAGCTTTATTGAAGTCTTCT TATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTATTCAAAATATTTTATCTTTTAGCTAGAATC CACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAATTTTTTAAAGAATCCAAGACAAACTAAAC TTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTTCTTTGAAATGCTAAACTTGGCTGTATGTC AAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTAATCAGAGTATCTGAAGGGAATTGTTTTTA TAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTTGTAAAGTAAAATATGTCCAGAAGAGTCAA AGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAATGTGCTAGAGTTAAAAGTTAGCATTGTTTC TAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTTGCTATACCACAGTCTTTCGTTTCCAGCCT TTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGCTGTATGAGCAGAGCAGTTCAAGGGCCAAA CCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCATTTGATCTGCCATGGACATGAGTTTAAAG CGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATGTAGTTACTGTGAGCCATATTACTAGTGCC CCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAACTTTAGAATTCCCAAGAGGGCTTTATTACA CCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGTGCTATAACATTCTGACACATATCATTCTG TGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTATTCCAATATGACCTTAAGGAAAAGTAAGGG AATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAGTCCTGAACCTTTCAAAATGGAAAATTAAT >In-frame_RFTN1_ENST00000432519_chr3_16450882_-_DAZL_ENST00000399444_chr3_16636090_-_2602nt CTCGTACAGTCCTTCATCTTCATGGCAGAAAGGCTGTTCTGCCCCTGCGCCCTCCCTGGCCTCTCTGGGGATCCCTGCAGCTGATGTATT GTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCCGCCCAGC TCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCCCTGGAGC ACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTAGATTGCT GTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGATGCCACCACAGTGGCCTGTTGGGGAGCAAAGGA GCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAGCTGAAGTTGTGCCAAATGAATGTTCAG TTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATACAAACGGTGGTATCTTGTCTGTTTAATC CAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGCATCACTTTAGAAGAAGTCGGGCAATGC TTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATATTAAGCTAAAAGGTTTCCACTATTATAGAA ATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCTAGTTTTATCTTAAACTGTTCTTCATTAGA TGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGACTGAAAGAAACTAAGATTTATCTGCAAGGA TTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTTTTAAAAACCTATTTTGAAAGGTCAGAATT TTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATTTACAGTATTGAGCTTTGCATTTATGATTT CTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCAATATATAGTTAGCTTTATTGAAGTCTTCT TATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTATTCAAAATATTTTATCTTTTAGCTAGAATC CACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAATTTTTTAAAGAATCCAAGACAAACTAAAC TTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTTCTTTGAAATGCTAAACTTGGCTGTATGTC AAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTAATCAGAGTATCTGAAGGGAATTGTTTTTA TAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTTGTAAAGTAAAATATGTCCAGAAGAGTCAA AGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAATGTGCTAGAGTTAAAAGTTAGCATTGTTTC TAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTTGCTATACCACAGTCTTTCGTTTCCAGCCT TTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGCTGTATGAGCAGAGCAGTTCAAGGGCCAAA CCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCATTTGATCTGCCATGGACATGAGTTTAAAG CGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATGTAGTTACTGTGAGCCATATTACTAGTGCC CCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAACTTTAGAATTCCCAAGAGGGCTTTATTACA CCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGTGCTATAACATTCTGACACATATCATTCTG TGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTATTCCAATATGACCTTAAGGAAAAGTAAGGG AATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAGTCCTGAACCTTTCAAAATGGAAAATTAAT >In-frame_RFTN1_ENST00000432519_chr3_16450882_-_DAZL_ENST00000250863_chr3_16640105_-_3169nt CTCGTACAGTCCTTCATCTTCATGGCAGAAAGGCTGTTCTGCCCCTGCGCCCTCCCTGGCCTCTCTGGGGATCCCTGCAGCTGATGTATT GTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCCGCCCAGC TCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCCCTGGAGC ACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTAGATTGCT GTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGTCTACTGCAAATCCTGAAACTCCAAACTCAACCA TCTCCAGAGAGGCCAGCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAACACTGTTT TTGTTGGAGGAATTGATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAGATAATCA CTGATCGAACTGGTGTGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAGATAAATT TCCATGGTAAAAAGCTGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTTTTTAATC ATCCTCCTCCACCACAGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCTATAACTC AGTATGTTCAGGCATATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAGATGCCAC CACAGTGGCCTGTTGGGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAG CTGAAGTTGTGCCAAATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATAC AAACGGTGGTATCTTGTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGC ATCACTTTAGAAGAAGTCGGGCAATGCTTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATATTA AGCTAAAAGGTTTCCACTATTATAGAAATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCTAG TTTTATCTTAAACTGTTCTTCATTAGATGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGACTG AAAGAAACTAAGATTTATCTGCAAGGATTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTTTT AAAAACCTATTTTGAAAGGTCAGAATTTTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATTTA CAGTATTGAGCTTTGCATTTATGATTTCTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCAAT ATATAGTTAGCTTTATTGAAGTCTTCTTATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTATTC AAAATATTTTATCTTTTAGCTAGAATCCACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAATT TTTTAAAGAATCCAAGACAAACTAAACTTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTTCT TTGAAATGCTAAACTTGGCTGTATGTCAAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTAAT CAGAGTATCTGAAGGGAATTGTTTTTATAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTTGT AAAGTAAAATATGTCCAGAAGAGTCAAAGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAATGT GCTAGAGTTAAAAGTTAGCATTGTTTCTAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTTGC TATACCACAGTCTTTCGTTTCCAGCCTTTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGCTG TATGAGCAGAGCAGTTCAAGGGCCAAACCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCATT TGATCTGCCATGGACATGAGTTTAAAGCGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATGTA GTTACTGTGAGCCATATTACTAGTGCCCCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAACTT TAGAATTCCCAAGAGGGCTTTATTACACCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGTGC TATAACATTCTGACACATATCATTCTGTGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTATTC CAATATGACCTTAAGGAAAAGTAAGGGAATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAGTC CTGAACCTTTCAAAATGGAAAATTAATTCTAAACTTAGAAATATGCTTCTGCCTATTGCTGATACTGTCTTTGCATACATGAATAAAAAT >In-frame_RFTN1_ENST00000432519_chr3_16450882_-_DAZL_ENST00000399444_chr3_16640105_-_3169nt CTCGTACAGTCCTTCATCTTCATGGCAGAAAGGCTGTTCTGCCCCTGCGCCCTCCCTGGCCTCTCTGGGGATCCCTGCAGCTGATGTATT GTGATGGAGCAGTGGACTTGGATGCTGCTGCGGAGCTCCCTGGGTCCTCAGCAGTGAGGCTGGCCTCCCTGCGTGACCTGCCCGCCCAGC TCCTGGAGCTGTACCAGCAGGGCTTCTCGCTGGCGGCCCTGCACCCCTTCGTGCAGCCCACCCATGAGCGGGAGAAGACGCCCCTGGAGC ACATCTTTAGAGCCATCCTGATCAAGAAAACCGACAGATCTCAGAAAACTGATCTTCACAATGAAGGCTACATCTTGGAATTAGATTGCT GTTCCTCCTTAGACCACCCGACAGACCAGAAACTCATCCCAGAGTTCATTAAGAAGTCTACTGCAAATCCTGAAACTCCAAACTCAACCA TCTCCAGAGAGGCCAGCACCCAGTCCTCATCAGCTGCAACCAGCCAAGGCTATATTTTACCAGAAGGCAAAATCATGCCAAACACTGTTT TTGTTGGAGGAATTGATGTTAGGATGGATGAAACTGAGATTAGAAGCTTCTTTGCTAGATATGGTTCAGTGAAAGAAGTGAAGATAATCA CTGATCGAACTGGTGTGTCCAAAGGCTATGGATTTGTTTCATTTTTTAATGACGTGGATGTGCAGAAGATAGTAGAATCACAGATAAATT TCCATGGTAAAAAGCTGAAGCTGGGCCCTGCAATCAGGAAACAAAATTTATGTGCTTATCATGTGCAGCCACGTCCTTTGGTTTTTAATC ATCCTCCTCCACCACAGTTTCAGAATGTCTGGACTAATCCAAACACTGAAACTTATATGCAGCCCACAACCACGATGAATCCTATAACTC AGTATGTTCAGGCATATCCTACTTACCCAAATTCACCAGTTCAGGTCATCACTGGATATCAGTTGCCTGTATATAATTATCAGATGCCAC CACAGTGGCCTGTTGGGGAGCAAAGGAGCTATGTTGTACCTCCGGCTTATTCAGCTGTTAACTACCACTGTAATGAAGTTGATCCAGGAG CTGAAGTTGTGCCAAATGAATGTTCAGTTCATGAAGCTACTCCACCCTCTGGAAATGGCCCACAAAAGAAATCTGTGGACCGAAGCATAC AAACGGTGGTATCTTGTCTGTTTAATCCAGAGAACAGACTGAGAAACTCTGTTGTTACTCAAGATGACTACTTCAAGGATAAAAGAGTGC ATCACTTTAGAAGAAGTCGGGCAATGCTTAAATCTGTTTGATCCTCCTGGCTTATCTAGTTACATGGGAAGTTGCTGGTTTTGAATATTA AGCTAAAAGGTTTCCACTATTATAGAAATTCTGAATTTTGGTAAATCACACTCAAACTTTGTGTATAAGTTGTATTATTAGACTCTCTAG TTTTATCTTAAACTGTTCTTCATTAGATGTTTATTTAGAAACTGGTTCTGTGTTGAAATATAGTTGAAAGTAAAAAAATAATTGAGACTG AAAGAAACTAAGATTTATCTGCAAGGATTTTTTAAAAATTGGCATTTTAAGTGTTTAAAAGCAAATACTGATTTTCAAAAAAATGTTTTT AAAAACCTATTTTGAAAGGTCAGAATTTTGTTGGTCTGAATACAAACATTTCACTTCTCCAACAAGTACCTGTGAACAGTACAGTATTTA CAGTATTGAGCTTTGCATTTATGATTTCTCCAGAAATTTACCACAAAAGCAAAATTTTTAAAACTGCATTTTTAATCAGTGGAACTCAAT ATATAGTTAGCTTTATTGAAGTCTTCTTATCTAAACCCAGCAAAACAGATTCAAAGCGAACAGTCCAATCAGTGGGTCATATGTTTATTC AAAATATTTTATCTTTTAGCTAGAATCCACACATATATATCCTATTTGATTAGGGTAGTAATTAGGATAACTAAAATTCTGGGCCTAATT TTTTAAAGAATCCAAGACAAACTAAACTTTACTAGGTACATAAGCTTCTCAATGAGTCACCATTCTTCTTTTTTGTAAAAACTTTTTTCT TTGAAATGCTAAACTTGGCTGTATGTCAAATTGTGCAAAATATTGGTATTAAAGAATGCTGCAACTTTTTTATGTCTCTTAGAGGTTAAT CAGAGTATCTGAAGGGAATTGTTTTTATAAAAACATTGAAATATTAGTTACTTGCTATAAATAGATTTAGTCTGTTATATTTCCTTTTGT AAAGTAAAATATGTCCAGAAGAGTCAAAGTAGTTAGTTTTGGTTATTTCTAAACCACAAAAGTTGTTTAATAAGTATATCTTAAGAATGT GCTAGAGTTAAAAGTTAGCATTGTTTCTAGATTAGCTGGTGTCTTCATTTTACATTGTGACAAACAGCTAGAGCATCAGAGCCCTTTTGC TATACCACAGTCTTTCGTTTCCAGCCTTTGTCACTAGTCTTTGAGGAGGTTTGCTCCTAGAACTGGTGATATAAAGAATGAAAGTAGCTG TATGAGCAGAGCAGTTCAAGGGCCAAACCCTGGAACGGTAGCAATGGGATATAATACCTTTCTAAGGGAAAAAGTTGTATCAGTACCATT TGATCTGCCATGGACATGAGTTTAAAGCGGCTTTCTGGCCCTTCTTTCAGTGACTTCTTCCCTAAAATGTAGAAATTCTAACTTAATGTA GTTACTGTGAGCCATATTACTAGTGCCCCCTAGGGTCTATAATTCCTTAAAATTTTCATTCTGAATCTGAAGGAGAGAGTCTTTTAACTT TAGAATTCCCAAGAGGGCTTTATTACACCTCAGAAATTGAAAGCACTATGAATTTGTCCATTTAAAAATGATCTGTAGTTTTTTTGGTGC TATAACATTCTGACACATATCATTCTGTGATTAAATCTCCAGCTTACTATAAATGATATCTATATTCTAAAGAGCTACTTCTAATTATTC CAATATGACCTTAAGGAAAAGTAAGGGAATAAATTTTTGTCTTTGTTGGAGTGAAGCATTTAAAAGAGTAAGGGTAAAAAAGATAAAGTC CTGAACCTTTCAAAATGGAAAATTAATTCTAAACTTAGAAATATGCTTCTGCCTATTGCTGATACTGTCTTTGCATACATGAATAAAAAT |
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FusionGenePPI for RFTN1_DAZL |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RFTN1 | SLC25A41, UNC119, MUS81, PTEN, CTDSPL, RABGAP1L, TGM5, ATG2A, SDC1, GJB7 | DAZL | DAZ1, DAZL, DAZAP1, DAZAP2, PUM2, EGFR |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for RFTN1_DAZL |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for RFTN1_DAZL |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | DAZL | C1336708 | Testicular Germ Cell Tumor | 1 | CTD_human |
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