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Fusion gene ID: 3083 |
FusionGeneSummary for ATAD2B_ITSN2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ATAD2B_ITSN2 | Fusion gene ID: 3083 | Hgene | Tgene | Gene symbol | ATAD2B | ITSN2 | Gene ID | 54454 | 50618 |
| Gene name | ATPase family, AAA domain containing 2B | intersectin 2 | |
| Synonyms | - | PRO2015|SH3D1B|SH3P18|SWA|SWAP | |
| Cytomap | 2p24.1-p23.3 | 2p23.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ATPase family AAA domain-containing protein 2B | intersectin-2SH3 domain-containing protein 1BSH3P18-like WASP-associated protein | |
| Modification date | 20180523 | 20180519 | |
| UniProtAcc | Q9ULI0 | Q9NZM3 | |
| Ensembl transtripts involved in fusion gene | ENST00000238789, ENST00000474583, | ENST00000361999, ENST00000355123, ENST00000406921, ENST00000407704, | |
| Fusion gene scores | * DoF score | 4 X 4 X 3=48 | 4 X 4 X 4=64 |
| # samples | 4 | 4 | |
| ** MAII score | log2(4/48*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/64*10)=-0.678071905112638 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ATAD2B [Title/Abstract] AND ITSN2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | ITSN2 | GO:1903861 | positive regulation of dendrite extension | 23999003 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | BRCA | TCGA-LL-A740-01A | ATAD2B | chr2 | 24021008 | - | ITSN2 | chr2 | 24426652 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000238789 | ENST00000361999 | ATAD2B | chr2 | 24021008 | - | ITSN2 | chr2 | 24426652 | - |
| In-frame | ENST00000238789 | ENST00000355123 | ATAD2B | chr2 | 24021008 | - | ITSN2 | chr2 | 24426652 | - |
| 5CDS-intron | ENST00000238789 | ENST00000406921 | ATAD2B | chr2 | 24021008 | - | ITSN2 | chr2 | 24426652 | - |
| 5CDS-intron | ENST00000238789 | ENST00000407704 | ATAD2B | chr2 | 24021008 | - | ITSN2 | chr2 | 24426652 | - |
| 5UTR-3CDS | ENST00000474583 | ENST00000361999 | ATAD2B | chr2 | 24021008 | - | ITSN2 | chr2 | 24426652 | - |
| 5UTR-3CDS | ENST00000474583 | ENST00000355123 | ATAD2B | chr2 | 24021008 | - | ITSN2 | chr2 | 24426652 | - |
| 5UTR-intron | ENST00000474583 | ENST00000406921 | ATAD2B | chr2 | 24021008 | - | ITSN2 | chr2 | 24426652 | - |
| 5UTR-intron | ENST00000474583 | ENST00000407704 | ATAD2B | chr2 | 24021008 | - | ITSN2 | chr2 | 24426652 | - |
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FusionProtFeatures for ATAD2B_ITSN2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ATAD2B | ITSN2 |
| Adapter protein that may provide indirect link betweenthe endocytic membrane traffic and the actin assembly machinery.May regulate the formation of clathrin-coated vesicles (CCPs).Seems to be involved in CCPs maturation including invagination orbudding. Involved in endocytosis of integrin beta-1 (ITGB1) andtransferrin receptor (TFR). Plays a role in dendrite formation bymelanocytes (PubMed:23999003). {ECO:0000269|PubMed:19458185,ECO:0000269|PubMed:22648170, ECO:0000269|PubMed:23999003}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ATAD2B | chr2:24021008 | chr2:24426652 | ENST00000238789 | - | 19 | 28 | 257_262 | 880 | 1459 | Compositional bias | Note=Poly-Glu |
| Hgene | ATAD2B | chr2:24021008 | chr2:24426652 | ENST00000238789 | - | 19 | 28 | 441_448 | 880 | 1459 | Nucleotide binding | ATP |
| Tgene | >ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000406921 | - | 0 | 30 | 67_79 | -80 | 1250 | Calcium binding | Ontology_term=ECO:0000255 |
| Tgene | >ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000406921 | - | 0 | 30 | 361_756 | -80 | 1250 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | >ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000406921 | - | 0 | 30 | 1053_1117 | -80 | 1250 | Domain | SH3 4 |
| Tgene | >ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000406921 | - | 0 | 30 | 1127_1186 | -80 | 1250 | Domain | SH3 5 |
| Tgene | >ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000406921 | - | 0 | 30 | 1209_1395 | -80 | 1250 | Domain | DH |
| Tgene | >ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000406921 | - | 0 | 30 | 1434_1544 | -80 | 1250 | Domain | PH |
| Tgene | >ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000406921 | - | 0 | 30 | 1556_1652 | -80 | 1250 | Domain | C2 |
| Tgene | >ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000406921 | - | 0 | 30 | 22_110 | -80 | 1250 | Domain | EH 1 |
| Tgene | >ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000406921 | - | 0 | 30 | 244_333 | -80 | 1250 | Domain | EH 2 |
| Tgene | >ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000406921 | - | 0 | 30 | 54_89 | -80 | 1250 | Domain | EF-hand |
| Tgene | >ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000406921 | - | 0 | 30 | 757_818 | -80 | 1250 | Domain | SH3 1 |
| Tgene | >ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000406921 | - | 0 | 30 | 898_956 | -80 | 1250 | Domain | SH3 2 |
| Tgene | >ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000406921 | - | 0 | 30 | 981_1039 | -80 | 1250 | Domain | SH3 3 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ATAD2B | chr2:24021008 | chr2:24426652 | ENST00000238789 | - | 19 | 28 | 943_974 | 880 | 1459 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | >ATAD2B | chr2:24021008 | chr2:24426652 | ENST00000238789 | - | 19 | 28 | 1247_1250 | 880 | 1459 | Compositional bias | Note=Poly-Ser |
| Hgene | >ATAD2B | chr2:24021008 | chr2:24426652 | ENST00000238789 | - | 19 | 28 | 975_1045 | 880 | 1459 | Domain | Bromo |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000355123 | - | 38 | 40 | 67_79 | 1645 | 1698 | Calcium binding | Ontology_term=ECO:0000255 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000361999 | - | 37 | 39 | 67_79 | 1618 | 1671 | Calcium binding | Ontology_term=ECO:0000255 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000355123 | - | 38 | 40 | 361_756 | 1645 | 1698 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000361999 | - | 37 | 39 | 361_756 | 1618 | 1671 | Coiled coil | Ontology_term=ECO:0000255 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000355123 | - | 38 | 40 | 1053_1117 | 1645 | 1698 | Domain | SH3 4 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000355123 | - | 38 | 40 | 1127_1186 | 1645 | 1698 | Domain | SH3 5 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000355123 | - | 38 | 40 | 1209_1395 | 1645 | 1698 | Domain | DH |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000355123 | - | 38 | 40 | 1434_1544 | 1645 | 1698 | Domain | PH |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000355123 | - | 38 | 40 | 1556_1652 | 1645 | 1698 | Domain | C2 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000355123 | - | 38 | 40 | 22_110 | 1645 | 1698 | Domain | EH 1 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000355123 | - | 38 | 40 | 244_333 | 1645 | 1698 | Domain | EH 2 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000355123 | - | 38 | 40 | 54_89 | 1645 | 1698 | Domain | EF-hand |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000355123 | - | 38 | 40 | 757_818 | 1645 | 1698 | Domain | SH3 1 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000355123 | - | 38 | 40 | 898_956 | 1645 | 1698 | Domain | SH3 2 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000355123 | - | 38 | 40 | 981_1039 | 1645 | 1698 | Domain | SH3 3 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000361999 | - | 37 | 39 | 1053_1117 | 1618 | 1671 | Domain | SH3 4 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000361999 | - | 37 | 39 | 1127_1186 | 1618 | 1671 | Domain | SH3 5 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000361999 | - | 37 | 39 | 1209_1395 | 1618 | 1671 | Domain | DH |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000361999 | - | 37 | 39 | 1434_1544 | 1618 | 1671 | Domain | PH |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000361999 | - | 37 | 39 | 1556_1652 | 1618 | 1671 | Domain | C2 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000361999 | - | 37 | 39 | 22_110 | 1618 | 1671 | Domain | EH 1 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000361999 | - | 37 | 39 | 244_333 | 1618 | 1671 | Domain | EH 2 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000361999 | - | 37 | 39 | 54_89 | 1618 | 1671 | Domain | EF-hand |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000361999 | - | 37 | 39 | 757_818 | 1618 | 1671 | Domain | SH3 1 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000361999 | - | 37 | 39 | 898_956 | 1618 | 1671 | Domain | SH3 2 |
| Tgene | ITSN2 | chr2:24021008 | chr2:24426652 | ENST00000361999 | - | 37 | 39 | 981_1039 | 1618 | 1671 | Domain | SH3 3 |
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FusionGeneSequence for ATAD2B_ITSN2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ATAD2B_ENST00000238789_chr2_24021008_-_ITSN2_ENST00000361999_chr2_24426652_-_932aa MVNTRKSSLRLLGSKSPGPGPGPGAGAEPGATGGSSHFISSRTRSSKTRAASCPAAKAGGSGGAGVTLDEARKVEVDGSLSDSHVSPPAK RTLKQPDSVCKDKSKSRSTGQREEWNLSTGQARLTSQPGATLPNGHSGLSLRSHPLRGEKKGDGDLSCINGDMEVRKSCRSRKNRFESVN QSLLFDQLVNSTAEAVLQEMDNINIRQNRRSGEVERLRMWTDTEFENMDMYSRVKRRRKSLRRNSYGIQNHHEVSTEGEEEESQEEDGDI EVEEAEGEENDRPYNLRQRKTVDRYQAPPIVPAHQKKRENTLFDIHRSPARRSHIRRKKHAIHSSDTTSSDEERFERRKSKSMARARNRC LPMNFRAEDLASGILRERVKVGASLADVDPMNIDKSVRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLV ARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDNRG EIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQKARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIALRRRYP QIYASSHKLQLDVSSIVLSAQDFYHAMQNIVPASQRAVMSSGHALSPIIRPLLERSFNNILAVLQKVFPHAEISQSDKKEDIETLILEDS EDENALSIFETNCHSGSPKKQSSSAAIHKPYLHFTMSPYHQPTSYRPRLLLSGERGSGQTSHLAPALLHTLERFSVHRLDLPALYSVSAK TPEESCAQIFREARRTVPSIVYMPHIGDWWEAVSETVRATFLTLLQDIPSFSPIFLLSTSETMYSELPEEISWVVLKFQWQKFEQNRKAK >In-frame_ATAD2B_ENST00000238789_chr2_24021008_-_ITSN2_ENST00000355123_chr2_24426652_-_932aa MVNTRKSSLRLLGSKSPGPGPGPGAGAEPGATGGSSHFISSRTRSSKTRAASCPAAKAGGSGGAGVTLDEARKVEVDGSLSDSHVSPPAK RTLKQPDSVCKDKSKSRSTGQREEWNLSTGQARLTSQPGATLPNGHSGLSLRSHPLRGEKKGDGDLSCINGDMEVRKSCRSRKNRFESVN QSLLFDQLVNSTAEAVLQEMDNINIRQNRRSGEVERLRMWTDTEFENMDMYSRVKRRRKSLRRNSYGIQNHHEVSTEGEEEESQEEDGDI EVEEAEGEENDRPYNLRQRKTVDRYQAPPIVPAHQKKRENTLFDIHRSPARRSHIRRKKHAIHSSDTTSSDEERFERRKSKSMARARNRC LPMNFRAEDLASGILRERVKVGASLADVDPMNIDKSVRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLV ARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDNRG EIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQKARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIALRRRYP QIYASSHKLQLDVSSIVLSAQDFYHAMQNIVPASQRAVMSSGHALSPIIRPLLERSFNNILAVLQKVFPHAEISQSDKKEDIETLILEDS EDENALSIFETNCHSGSPKKQSSSAAIHKPYLHFTMSPYHQPTSYRPRLLLSGERGSGQTSHLAPALLHTLERFSVHRLDLPALYSVSAK TPEESCAQIFREARRTVPSIVYMPHIGDWWEAVSETVRATFLTLLQDIPSFSPIFLLSTSETMYSELPEEISWVVLKFQWQKFEQNRKAK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ATAD2B_ENST00000238789_chr2_24021008_-_ITSN2_ENST00000361999_chr2_24426652_-_2798nt ATGGTGAACACCCGGAAGAGCTCTCTCCGCCTTCTCGGGTCCAAGTCTCCTGGTCCCGGGCCTGGGCCTGGGGCCGGAGCAGAGCCTGGG GCGACCGGAGGCAGCAGCCATTTCATCTCCTCTCGGACCCGCTCCTCCAAGACCCGCGCCGCCAGCTGCCCCGCCGCCAAAGCCGGGGGA AGCGGTGGCGCCGGCGTCACTCTGGATGAGGCCAGGAAAGTTGAAGTTGATGGTAGTTTAAGTGATAGCCACGTATCTCCTCCAGCCAAA CGCACTTTGAAACAACCTGATTCTGTTTGCAAAGACAAATCAAAATCACGAAGTACTGGTCAGCGAGAGGAATGGAACTTATCAACTGGA CAGGCCAGGTTAACTTCTCAGCCTGGTGCTACATTACCAAATGGACATAGTGGCTTATCCCTTCGAAGCCATCCCCTTCGAGGGGAAAAG AAGGGAGATGGGGACCTTTCTTGTATAAATGGTGACATGGAAGTCAGAAAAAGTTGTCGTTCCAGGAAAAACAGATTTGAAAGTGTGAAC CAGAGTTTGTTATTTGATCAACTAGTAAATAGCACTGCTGAAGCTGTACTACAGGAAATGGACAACATTAACATCCGACAGAATCGTCGA TCAGGAGAAGTAGAACGACTTCGAATGTGGACAGATACAGAATTTGAAAACATGGATATGTATTCAAGAGTGAAAAGGCGAAGAAAGTCA CTAAGAAGAAATAGTTATGGGATACAAAATCATCATGAAGTTTCTACTGAGGGTGAAGAAGAAGAATCTCAAGAGGAGGATGGAGATATA GAAGTTGAAGAGGCAGAAGGAGAAGAAAATGATAGACCATATAATTTGAGACAGAGAAAAACAGTGGATCGATACCAAGCACCTCCAATA GTACCAGCTCATCAAAAAAAGAGGGAAAACACGCTGTTTGATATTCATAGATCTCCAGCAAGAAGAAGCCATATTAGGAGAAAGAAGCAT GCCATTCATAGTAGTGACACAACTTCTTCTGATGAGGAACGCTTTGAAAGAAGGAAATCAAAGAGCATGGCAAGAGCAAGAAATAGATGT TTGCCTATGAACTTCAGAGCAGAGGACTTAGCTAGCGGTATTCTCCGAGAACGAGTGAAAGTGGGTGCAAGCTTGGCTGATGTTGATCCA ATGAACATTGATAAATCAGTACGGTTTGATAGCATAGGTGGATTGAGCCATCATATTCATGCGCTAAAGGAAATGGTAGTATTCCCACTT TTATATCCAGAAATTTTTGAAAAGTTTAAAATTCAGCCTCCAAGGGGCTGTTTGTTTTATGGCCCTCCTGGCACAGGTAAAACCTTGGTT GCCAGAGCATTAGCTAATGAATGCAGCCAAGGAGACAAAAAAGTGGCTTTTTTTATGCGAAAAGGAGCAGATTGTTTGAGCAAGTGGGTT GGTGAATCTGAAAGGCAACTTAGGCTTCTTTTTGATCAGGCATATTTGATGAGACCTTCTATAATATTTTTTGATGAAATAGATGGATTA GCTCCAGTTCGCTCTAGCAGACAAGATCAGATCCACAGCTCTATAGTATCAACCCTCCTTGCTCTTATGGATGGATTAGATAATAGGGGT GAAATTGTTGTTATTGGTGCTACAAACAGACTTGACTCTATAGATCCTGCACTCAGGAGACCTGGTCGTTTTGACAGAGAATTCCTCTTC AACCTGCCTGATCAAAAGGCAAGAAAACACATCTTACAGATCCATACCAGGGACTGGAATCCAAAATTGTCAGATGCATTTTTAGGTGAA TTGGCTGAAAAATGTGTTGGCTACTGTGGAGCCGATATCAAGGCCCTGTGCACTGAAGCCGCCCTGATTGCACTGCGGAGGCGTTATCCC CAGATCTATGCTAGCAGTCATAAACTGCAGCTGGATGTTTCCTCAATAGTGCTTAGTGCCCAAGATTTTTACCATGCAATGCAGAATATC GTGCCTGCTTCCCAACGTGCTGTGATGTCTTCAGGGCATGCACTATCCCCCATCATAAGACCACTGCTGGAAAGAAGCTTCAACAACATC CTAGCAGTCTTGCAAAAAGTGTTTCCTCATGCTGAAATTAGCCAGAGTGACAAAAAAGAAGATATAGAAACTTTAATTTTAGAGGATAGT GAAGATGAAAATGCTTTATCAATTTTTGAGACCAATTGTCACTCAGGATCACCAAAGAAACAGTCATCATCTGCTGCTATACATAAACCC TACCTTCATTTTACAATGTCACCATATCATCAGCCAACCTCTTACAGGCCACGCTTATTGCTCTCTGGAGAACGGGGCTCAGGTCAAACT TCTCACCTTGCTCCAGCACTTTTGCACACTCTAGAAAGATTCTCTGTGCATAGACTAGATCTCCCAGCACTTTATTCAGTTAGTGCCAAA ACACCTGAGGAATCATGTGCACAGATTTTTCGTGAAGCTCGAAGAACAGTACCTAGTATTGTTTACATGCCTCACATTGGGGATTGGTGG GAAGCTGTCAGTGAAACTGTGAGAGCAACTTTTCTGACATTGCTACAAGATATACCATCATTTTCACCTATATTTTTATTGTCTACCTCT GAAACCATGTACAGTGAACTGCCTGAAGAGATTTCCTGGGTCGTACTGAAATTCCAGTGGCAAAAATTCGAACAGAACAGGAAAGCAAAG GCCCTATGACCCGCCGACTGCTGCTGCATGAGGTCCCCACCGGGGAGGTCTGGGTCCGTTTTGACCTGCAGCTTTTTGAGCAAAAAACTC >In-frame_ATAD2B_ENST00000238789_chr2_24021008_-_ITSN2_ENST00000355123_chr2_24426652_-_2798nt ATGGTGAACACCCGGAAGAGCTCTCTCCGCCTTCTCGGGTCCAAGTCTCCTGGTCCCGGGCCTGGGCCTGGGGCCGGAGCAGAGCCTGGG GCGACCGGAGGCAGCAGCCATTTCATCTCCTCTCGGACCCGCTCCTCCAAGACCCGCGCCGCCAGCTGCCCCGCCGCCAAAGCCGGGGGA AGCGGTGGCGCCGGCGTCACTCTGGATGAGGCCAGGAAAGTTGAAGTTGATGGTAGTTTAAGTGATAGCCACGTATCTCCTCCAGCCAAA CGCACTTTGAAACAACCTGATTCTGTTTGCAAAGACAAATCAAAATCACGAAGTACTGGTCAGCGAGAGGAATGGAACTTATCAACTGGA CAGGCCAGGTTAACTTCTCAGCCTGGTGCTACATTACCAAATGGACATAGTGGCTTATCCCTTCGAAGCCATCCCCTTCGAGGGGAAAAG AAGGGAGATGGGGACCTTTCTTGTATAAATGGTGACATGGAAGTCAGAAAAAGTTGTCGTTCCAGGAAAAACAGATTTGAAAGTGTGAAC CAGAGTTTGTTATTTGATCAACTAGTAAATAGCACTGCTGAAGCTGTACTACAGGAAATGGACAACATTAACATCCGACAGAATCGTCGA TCAGGAGAAGTAGAACGACTTCGAATGTGGACAGATACAGAATTTGAAAACATGGATATGTATTCAAGAGTGAAAAGGCGAAGAAAGTCA CTAAGAAGAAATAGTTATGGGATACAAAATCATCATGAAGTTTCTACTGAGGGTGAAGAAGAAGAATCTCAAGAGGAGGATGGAGATATA GAAGTTGAAGAGGCAGAAGGAGAAGAAAATGATAGACCATATAATTTGAGACAGAGAAAAACAGTGGATCGATACCAAGCACCTCCAATA GTACCAGCTCATCAAAAAAAGAGGGAAAACACGCTGTTTGATATTCATAGATCTCCAGCAAGAAGAAGCCATATTAGGAGAAAGAAGCAT GCCATTCATAGTAGTGACACAACTTCTTCTGATGAGGAACGCTTTGAAAGAAGGAAATCAAAGAGCATGGCAAGAGCAAGAAATAGATGT TTGCCTATGAACTTCAGAGCAGAGGACTTAGCTAGCGGTATTCTCCGAGAACGAGTGAAAGTGGGTGCAAGCTTGGCTGATGTTGATCCA ATGAACATTGATAAATCAGTACGGTTTGATAGCATAGGTGGATTGAGCCATCATATTCATGCGCTAAAGGAAATGGTAGTATTCCCACTT TTATATCCAGAAATTTTTGAAAAGTTTAAAATTCAGCCTCCAAGGGGCTGTTTGTTTTATGGCCCTCCTGGCACAGGTAAAACCTTGGTT GCCAGAGCATTAGCTAATGAATGCAGCCAAGGAGACAAAAAAGTGGCTTTTTTTATGCGAAAAGGAGCAGATTGTTTGAGCAAGTGGGTT GGTGAATCTGAAAGGCAACTTAGGCTTCTTTTTGATCAGGCATATTTGATGAGACCTTCTATAATATTTTTTGATGAAATAGATGGATTA GCTCCAGTTCGCTCTAGCAGACAAGATCAGATCCACAGCTCTATAGTATCAACCCTCCTTGCTCTTATGGATGGATTAGATAATAGGGGT GAAATTGTTGTTATTGGTGCTACAAACAGACTTGACTCTATAGATCCTGCACTCAGGAGACCTGGTCGTTTTGACAGAGAATTCCTCTTC AACCTGCCTGATCAAAAGGCAAGAAAACACATCTTACAGATCCATACCAGGGACTGGAATCCAAAATTGTCAGATGCATTTTTAGGTGAA TTGGCTGAAAAATGTGTTGGCTACTGTGGAGCCGATATCAAGGCCCTGTGCACTGAAGCCGCCCTGATTGCACTGCGGAGGCGTTATCCC CAGATCTATGCTAGCAGTCATAAACTGCAGCTGGATGTTTCCTCAATAGTGCTTAGTGCCCAAGATTTTTACCATGCAATGCAGAATATC GTGCCTGCTTCCCAACGTGCTGTGATGTCTTCAGGGCATGCACTATCCCCCATCATAAGACCACTGCTGGAAAGAAGCTTCAACAACATC CTAGCAGTCTTGCAAAAAGTGTTTCCTCATGCTGAAATTAGCCAGAGTGACAAAAAAGAAGATATAGAAACTTTAATTTTAGAGGATAGT GAAGATGAAAATGCTTTATCAATTTTTGAGACCAATTGTCACTCAGGATCACCAAAGAAACAGTCATCATCTGCTGCTATACATAAACCC TACCTTCATTTTACAATGTCACCATATCATCAGCCAACCTCTTACAGGCCACGCTTATTGCTCTCTGGAGAACGGGGCTCAGGTCAAACT TCTCACCTTGCTCCAGCACTTTTGCACACTCTAGAAAGATTCTCTGTGCATAGACTAGATCTCCCAGCACTTTATTCAGTTAGTGCCAAA ACACCTGAGGAATCATGTGCACAGATTTTTCGTGAAGCTCGAAGAACAGTACCTAGTATTGTTTACATGCCTCACATTGGGGATTGGTGG GAAGCTGTCAGTGAAACTGTGAGAGCAACTTTTCTGACATTGCTACAAGATATACCATCATTTTCACCTATATTTTTATTGTCTACCTCT GAAACCATGTACAGTGAACTGCCTGAAGAGATTTCCTGGGTCGTACTGAAATTCCAGTGGCAAAAATTCGAACAGAACAGGAAAGCAAAG GCCCTATGACCCGCCGACTGCTGCTGCATGAGGTCCCCACCGGGGAGGTCTGGGTCCGTTTTGACCTGCAGCTTTTTGAGCAAAAAACTC |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ATAD2B_ENST00000238789_chr2_24021008_-_ITSN2_ENST00000361999_chr2_24426652_-_3904nt CCTGCGGCGCTGGAGCCTTGACGCACGGAGCTCGAGAGCGAGAACGGGAGAGAAAGGGGTAGAAATGGCGGCTCCGCTCGGCTCCCGCTG AGGAGGGCGAAGCCGGCGGAGTGTCTGTGCTGCCGGTCTGCAGCACCGCCCCCGCTTCCCGCACGCCGCCTGCTCACGCCGACTTCCCTT CCTCTGCCCGGCTCTCTCTTGTGCTCGTCTGCGCTCCGCACGCTCCGGGCCGGCTCGTCTCTCATTGCCCGGCTCGGCTCCGCTGGCCCT GACTGACCGGCCGGCGGGCCGGCCTTGCTCGGCTCTCCCGGGCGCGGCGTGGACTCCGTCCCCCTGGCTGGACCATGGTGAACACCCGGA AGAGCTCTCTCCGCCTTCTCGGGTCCAAGTCTCCTGGTCCCGGGCCTGGGCCTGGGGCCGGAGCAGAGCCTGGGGCGACCGGAGGCAGCA GCCATTTCATCTCCTCTCGGACCCGCTCCTCCAAGACCCGCGCCGCCAGCTGCCCCGCCGCCAAAGCCGGGGGAAGCGGTGGCGCCGGCG TCACTCTGGATGAGGCCAGGAAAGTTGAAGTTGATGGTAGTTTAAGTGATAGCCACGTATCTCCTCCAGCCAAACGCACTTTGAAACAAC CTGATTCTGTTTGCAAAGACAAATCAAAATCACGAAGTACTGGTCAGCGAGAGGAATGGAACTTATCAACTGGACAGGCCAGGTTAACTT CTCAGCCTGGTGCTACATTACCAAATGGACATAGTGGCTTATCCCTTCGAAGCCATCCCCTTCGAGGGGAAAAGAAGGGAGATGGGGACC TTTCTTGTATAAATGGTGACATGGAAGTCAGAAAAAGTTGTCGTTCCAGGAAAAACAGATTTGAAAGTGTGAACCAGAGTTTGTTATTTG ATCAACTAGTAAATAGCACTGCTGAAGCTGTACTACAGGAAATGGACAACATTAACATCCGACAGAATCGTCGATCAGGAGAAGTAGAAC GACTTCGAATGTGGACAGATACAGAATTTGAAAACATGGATATGTATTCAAGAGTGAAAAGGCGAAGAAAGTCACTAAGAAGAAATAGTT ATGGGATACAAAATCATCATGAAGTTTCTACTGAGGGTGAAGAAGAAGAATCTCAAGAGGAGGATGGAGATATAGAAGTTGAAGAGGCAG AAGGAGAAGAAAATGATAGACCATATAATTTGAGACAGAGAAAAACAGTGGATCGATACCAAGCACCTCCAATAGTACCAGCTCATCAAA AAAAGAGGGAAAACACGCTGTTTGATATTCATAGATCTCCAGCAAGAAGAAGCCATATTAGGAGAAAGAAGCATGCCATTCATAGTAGTG ACACAACTTCTTCTGATGAGGAACGCTTTGAAAGAAGGAAATCAAAGAGCATGGCAAGAGCAAGAAATAGATGTTTGCCTATGAACTTCA GAGCAGAGGACTTAGCTAGCGGTATTCTCCGAGAACGAGTGAAAGTGGGTGCAAGCTTGGCTGATGTTGATCCAATGAACATTGATAAAT CAGTACGGTTTGATAGCATAGGTGGATTGAGCCATCATATTCATGCGCTAAAGGAAATGGTAGTATTCCCACTTTTATATCCAGAAATTT TTGAAAAGTTTAAAATTCAGCCTCCAAGGGGCTGTTTGTTTTATGGCCCTCCTGGCACAGGTAAAACCTTGGTTGCCAGAGCATTAGCTA ATGAATGCAGCCAAGGAGACAAAAAAGTGGCTTTTTTTATGCGAAAAGGAGCAGATTGTTTGAGCAAGTGGGTTGGTGAATCTGAAAGGC AACTTAGGCTTCTTTTTGATCAGGCATATTTGATGAGACCTTCTATAATATTTTTTGATGAAATAGATGGATTAGCTCCAGTTCGCTCTA GCAGACAAGATCAGATCCACAGCTCTATAGTATCAACCCTCCTTGCTCTTATGGATGGATTAGATAATAGGGGTGAAATTGTTGTTATTG GTGCTACAAACAGACTTGACTCTATAGATCCTGCACTCAGGAGACCTGGTCGTTTTGACAGAGAATTCCTCTTCAACCTGCCTGATCAAA AGGCAAGAAAACACATCTTACAGATCCATACCAGGGACTGGAATCCAAAATTGTCAGATGCATTTTTAGGTGAATTGGCTGAAAAATGTG TTGGCTACTGTGGAGCCGATATCAAGGCCCTGTGCACTGAAGCCGCCCTGATTGCACTGCGGAGGCGTTATCCCCAGATCTATGCTAGCA GTCATAAACTGCAGCTGGATGTTTCCTCAATAGTGCTTAGTGCCCAAGATTTTTACCATGCAATGCAGAATATCGTGCCTGCTTCCCAAC GTGCTGTGATGTCTTCAGGGCATGCACTATCCCCCATCATAAGACCACTGCTGGAAAGAAGCTTCAACAACATCCTAGCAGTCTTGCAAA AAGTGTTTCCTCATGCTGAAATTAGCCAGAGTGACAAAAAAGAAGATATAGAAACTTTAATTTTAGAGGATAGTGAAGATGAAAATGCTT TATCAATTTTTGAGACCAATTGTCACTCAGGATCACCAAAGAAACAGTCATCATCTGCTGCTATACATAAACCCTACCTTCATTTTACAA TGTCACCATATCATCAGCCAACCTCTTACAGGCCACGCTTATTGCTCTCTGGAGAACGGGGCTCAGGTCAAACTTCTCACCTTGCTCCAG CACTTTTGCACACTCTAGAAAGATTCTCTGTGCATAGACTAGATCTCCCAGCACTTTATTCAGTTAGTGCCAAAACACCTGAGGAATCAT GTGCACAGATTTTTCGTGAAGCTCGAAGAACAGTACCTAGTATTGTTTACATGCCTCACATTGGGGATTGGTGGGAAGCTGTCAGTGAAA CTGTGAGAGCAACTTTTCTGACATTGCTACAAGATATACCATCATTTTCACCTATATTTTTATTGTCTACCTCTGAAACCATGTACAGTG AACTGCCTGAAGAGATTTCCTGGGTCGTACTGAAATTCCAGTGGCAAAAATTCGAACAGAACAGGAAAGCAAAGGCCCTATGACCCGCCG ACTGCTGCTGCATGAGGTCCCCACCGGGGAGGTCTGGGTCCGTTTTGACCTGCAGCTTTTTGAGCAAAAAACTCTCCTGTAGGGGTTCTA AAGGACAGCACCAGCGGGACAGCCCACAAGGCTGGGGCTGGAGAATGAGAGACTGCGCTCTCTTGGGGCTGAGGGAGCACCATGCAGCTT CACCCCTCACAAAGCCATGCACGCTGGGGGCTCTGTTTTCCTGCACACTAAATAGCTAGCAATCTATGCAAACACCTTTCCCATAAAGAA ACCAAACCCCATAGTACAGTGCCTTGTCCTAGTGTTCACATGTTCAGCTCTGTTTGTTTAGATGCCAAGGTTTCCATTTTCAGGGCTATA AAAAGTATTACTTGGAAATGAGGCATCAGACCACCAGATGTTACCGCTCGGTTGAATGTGTCCACCGTGGAGTGGTTTGGTGACGCTGTA ACCATTCCACGCCAGTGACCTCTGCTGGGTCACAGCCACTCAGGAGGGGAAGGGTCAGGATGAGAGGCTGCAGCCTCGACACTTGGCGCG GCCTGATACTGAAATAGCGTCTACTCGTGCACTGAATAAAAACAGAAACTTGATCATTTTATTCCTGATTAGATTTTATCACTCTCTGCT AAGACAATATAGTCTGGAGTATAAGTGGGAAAGCTTGATTTAAATACTGTGAACTCTAATAATGTGGAAAATATTTTTCAACTTTAATTT TCTGAAGTATAAATTATTTATGTAAATTCATTGTTTTTGCATATTTCTTAGGACATGCATCTTTAAGCTTTATCATTGCCCATATGTACA >In-frame_ATAD2B_ENST00000238789_chr2_24021008_-_ITSN2_ENST00000355123_chr2_24426652_-_3904nt CCTGCGGCGCTGGAGCCTTGACGCACGGAGCTCGAGAGCGAGAACGGGAGAGAAAGGGGTAGAAATGGCGGCTCCGCTCGGCTCCCGCTG AGGAGGGCGAAGCCGGCGGAGTGTCTGTGCTGCCGGTCTGCAGCACCGCCCCCGCTTCCCGCACGCCGCCTGCTCACGCCGACTTCCCTT CCTCTGCCCGGCTCTCTCTTGTGCTCGTCTGCGCTCCGCACGCTCCGGGCCGGCTCGTCTCTCATTGCCCGGCTCGGCTCCGCTGGCCCT GACTGACCGGCCGGCGGGCCGGCCTTGCTCGGCTCTCCCGGGCGCGGCGTGGACTCCGTCCCCCTGGCTGGACCATGGTGAACACCCGGA AGAGCTCTCTCCGCCTTCTCGGGTCCAAGTCTCCTGGTCCCGGGCCTGGGCCTGGGGCCGGAGCAGAGCCTGGGGCGACCGGAGGCAGCA GCCATTTCATCTCCTCTCGGACCCGCTCCTCCAAGACCCGCGCCGCCAGCTGCCCCGCCGCCAAAGCCGGGGGAAGCGGTGGCGCCGGCG TCACTCTGGATGAGGCCAGGAAAGTTGAAGTTGATGGTAGTTTAAGTGATAGCCACGTATCTCCTCCAGCCAAACGCACTTTGAAACAAC CTGATTCTGTTTGCAAAGACAAATCAAAATCACGAAGTACTGGTCAGCGAGAGGAATGGAACTTATCAACTGGACAGGCCAGGTTAACTT CTCAGCCTGGTGCTACATTACCAAATGGACATAGTGGCTTATCCCTTCGAAGCCATCCCCTTCGAGGGGAAAAGAAGGGAGATGGGGACC TTTCTTGTATAAATGGTGACATGGAAGTCAGAAAAAGTTGTCGTTCCAGGAAAAACAGATTTGAAAGTGTGAACCAGAGTTTGTTATTTG ATCAACTAGTAAATAGCACTGCTGAAGCTGTACTACAGGAAATGGACAACATTAACATCCGACAGAATCGTCGATCAGGAGAAGTAGAAC GACTTCGAATGTGGACAGATACAGAATTTGAAAACATGGATATGTATTCAAGAGTGAAAAGGCGAAGAAAGTCACTAAGAAGAAATAGTT ATGGGATACAAAATCATCATGAAGTTTCTACTGAGGGTGAAGAAGAAGAATCTCAAGAGGAGGATGGAGATATAGAAGTTGAAGAGGCAG AAGGAGAAGAAAATGATAGACCATATAATTTGAGACAGAGAAAAACAGTGGATCGATACCAAGCACCTCCAATAGTACCAGCTCATCAAA AAAAGAGGGAAAACACGCTGTTTGATATTCATAGATCTCCAGCAAGAAGAAGCCATATTAGGAGAAAGAAGCATGCCATTCATAGTAGTG ACACAACTTCTTCTGATGAGGAACGCTTTGAAAGAAGGAAATCAAAGAGCATGGCAAGAGCAAGAAATAGATGTTTGCCTATGAACTTCA GAGCAGAGGACTTAGCTAGCGGTATTCTCCGAGAACGAGTGAAAGTGGGTGCAAGCTTGGCTGATGTTGATCCAATGAACATTGATAAAT CAGTACGGTTTGATAGCATAGGTGGATTGAGCCATCATATTCATGCGCTAAAGGAAATGGTAGTATTCCCACTTTTATATCCAGAAATTT TTGAAAAGTTTAAAATTCAGCCTCCAAGGGGCTGTTTGTTTTATGGCCCTCCTGGCACAGGTAAAACCTTGGTTGCCAGAGCATTAGCTA ATGAATGCAGCCAAGGAGACAAAAAAGTGGCTTTTTTTATGCGAAAAGGAGCAGATTGTTTGAGCAAGTGGGTTGGTGAATCTGAAAGGC AACTTAGGCTTCTTTTTGATCAGGCATATTTGATGAGACCTTCTATAATATTTTTTGATGAAATAGATGGATTAGCTCCAGTTCGCTCTA GCAGACAAGATCAGATCCACAGCTCTATAGTATCAACCCTCCTTGCTCTTATGGATGGATTAGATAATAGGGGTGAAATTGTTGTTATTG GTGCTACAAACAGACTTGACTCTATAGATCCTGCACTCAGGAGACCTGGTCGTTTTGACAGAGAATTCCTCTTCAACCTGCCTGATCAAA AGGCAAGAAAACACATCTTACAGATCCATACCAGGGACTGGAATCCAAAATTGTCAGATGCATTTTTAGGTGAATTGGCTGAAAAATGTG TTGGCTACTGTGGAGCCGATATCAAGGCCCTGTGCACTGAAGCCGCCCTGATTGCACTGCGGAGGCGTTATCCCCAGATCTATGCTAGCA GTCATAAACTGCAGCTGGATGTTTCCTCAATAGTGCTTAGTGCCCAAGATTTTTACCATGCAATGCAGAATATCGTGCCTGCTTCCCAAC GTGCTGTGATGTCTTCAGGGCATGCACTATCCCCCATCATAAGACCACTGCTGGAAAGAAGCTTCAACAACATCCTAGCAGTCTTGCAAA AAGTGTTTCCTCATGCTGAAATTAGCCAGAGTGACAAAAAAGAAGATATAGAAACTTTAATTTTAGAGGATAGTGAAGATGAAAATGCTT TATCAATTTTTGAGACCAATTGTCACTCAGGATCACCAAAGAAACAGTCATCATCTGCTGCTATACATAAACCCTACCTTCATTTTACAA TGTCACCATATCATCAGCCAACCTCTTACAGGCCACGCTTATTGCTCTCTGGAGAACGGGGCTCAGGTCAAACTTCTCACCTTGCTCCAG CACTTTTGCACACTCTAGAAAGATTCTCTGTGCATAGACTAGATCTCCCAGCACTTTATTCAGTTAGTGCCAAAACACCTGAGGAATCAT GTGCACAGATTTTTCGTGAAGCTCGAAGAACAGTACCTAGTATTGTTTACATGCCTCACATTGGGGATTGGTGGGAAGCTGTCAGTGAAA CTGTGAGAGCAACTTTTCTGACATTGCTACAAGATATACCATCATTTTCACCTATATTTTTATTGTCTACCTCTGAAACCATGTACAGTG AACTGCCTGAAGAGATTTCCTGGGTCGTACTGAAATTCCAGTGGCAAAAATTCGAACAGAACAGGAAAGCAAAGGCCCTATGACCCGCCG ACTGCTGCTGCATGAGGTCCCCACCGGGGAGGTCTGGGTCCGTTTTGACCTGCAGCTTTTTGAGCAAAAAACTCTCCTGTAGGGGTTCTA AAGGACAGCACCAGCGGGACAGCCCACAAGGCTGGGGCTGGAGAATGAGAGACTGCGCTCTCTTGGGGCTGAGGGAGCACCATGCAGCTT CACCCCTCACAAAGCCATGCACGCTGGGGGCTCTGTTTTCCTGCACACTAAATAGCTAGCAATCTATGCAAACACCTTTCCCATAAAGAA ACCAAACCCCATAGTACAGTGCCTTGTCCTAGTGTTCACATGTTCAGCTCTGTTTGTTTAGATGCCAAGGTTTCCATTTTCAGGGCTATA AAAAGTATTACTTGGAAATGAGGCATCAGACCACCAGATGTTACCGCTCGGTTGAATGTGTCCACCGTGGAGTGGTTTGGTGACGCTGTA ACCATTCCACGCCAGTGACCTCTGCTGGGTCACAGCCACTCAGGAGGGGAAGGGTCAGGATGAGAGGCTGCAGCCTCGACACTTGGCGCG GCCTGATACTGAAATAGCGTCTACTCGTGCACTGAATAAAAACAGAAACTTGATCATTTTATTCCTGATTAGATTTTATCACTCTCTGCT AAGACAATATAGTCTGGAGTATAAGTGGGAAAGCTTGATTTAAATACTGTGAACTCTAATAATGTGGAAAATATTTTTCAACTTTAATTT TCTGAAGTATAAATTATTTATGTAAATTCATTGTTTTTGCATATTTCTTAGGACATGCATCTTTAAGCTTTATCATTGCCCATATGTACA |
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FusionGenePPI for ATAD2B_ITSN2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ATAD2B | SIRT7 | ITSN2 | BCCIP, PTN, TBL3, WAS, FCHSD1, SRGAP2, MAP4K3, SOS1, SEMA6A, SYNJ2, KIAA1549, YTHDF1, FNBP4, SNAP29, NR2C2, KDM1A, KXD1, LUC7L3, EPS15, EPS15L1, ERC1, GOLGA8A, GOLGB1, HOOK2, KCTD10, NBR1, PDE4DIP, RNF20, STX4, TACC1, TRIO, ANKRD17, CCDC88C, DST, RABEP1, ROCK1, RUFY1, TMF1, AGT, AHDC1, CBL, CHIC2, CPSF6, DNM2, FASLG, FCHSD2, GPNMB, ITPKA, LARP6, LTBP4, MBNL1, PDCD6IP, PIK3AP1, PIK3C2B, RBMX, REPS1, DLGAP1, SH3KBP1, SOS2, SYN1, WASL, WIPF1, WIPF2, GOLGA2, SH3GL1, AMPH, YLPM1, WASF2, HNRNPK, GAREML, ITSN1, ITSN2, KHDRBS1, PPP1CC, PSEN1, LSM8, EGFR, AP2M1, FBF1, NINL, EZH2, TM9SF4, RNF41, GOLT1B, SMEK1, MRPL9, NCKIPSD, AP2S1, UBC |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ATAD2B_ITSN2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ATAD2B_ITSN2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Tgene | ITSN2 | C0027643 | Neoplasm Recurrence, Local | 1 | CTD_human |
| Tgene | ITSN2 | C1458155 | Mammary Neoplasms | 1 | CTD_human |
| Tgene | ITSN2 | C1527336 | Sjogren's Syndrome | 1 | CTD_human |
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