|
||||||
|
 | |
| |
| |
| |
| |
|
Fusion gene ID: 3079 |
FusionGeneSummary for ATAD1_LIPF |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ATAD1_LIPF | Fusion gene ID: 3079 | Hgene | Tgene | Gene symbol | ATAD1 | LIPF | Gene ID | 84896 | 8513 |
| Gene name | ATPase family, AAA domain containing 1 | lipase F, gastric type | |
| Synonyms | AFDC1|FNP001|THORASE | GL|HGL|HLAL | |
| Cytomap | 10q23.31 | 10q23.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ATPase family AAA domain-containing protein 1 | gastric triacylglycerol lipasegastric lipaselipase, gastric | |
| Modification date | 20180522 | 20180523 | |
| UniProtAcc | Q8NBU5 | P07098 | |
| Ensembl transtripts involved in fusion gene | ENST00000308448, ENST00000328142, ENST00000400215, ENST00000541004, ENST00000495903, | ENST00000394375, ENST00000608620, ENST00000238983, ENST00000355843, | |
| Fusion gene scores | * DoF score | 8 X 4 X 5=160 | 8 X 7 X 5=280 |
| # samples | 7 | 8 | |
| ** MAII score | log2(7/160*10)=-1.1926450779424 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/280*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ATAD1 [Title/Abstract] AND LIPF [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | LGG | TCGA-E1-A7YN-01A | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000308448 | ENST00000394375 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5CDS-5UTR | ENST00000308448 | ENST00000608620 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5CDS-5UTR | ENST00000308448 | ENST00000238983 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5CDS-5UTR | ENST00000308448 | ENST00000355843 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| In-frame | ENST00000328142 | ENST00000394375 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5CDS-5UTR | ENST00000328142 | ENST00000608620 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5CDS-5UTR | ENST00000328142 | ENST00000238983 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5CDS-5UTR | ENST00000328142 | ENST00000355843 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| In-frame | ENST00000400215 | ENST00000394375 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5CDS-5UTR | ENST00000400215 | ENST00000608620 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5CDS-5UTR | ENST00000400215 | ENST00000238983 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5CDS-5UTR | ENST00000400215 | ENST00000355843 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| Frame-shift | ENST00000541004 | ENST00000394375 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5CDS-5UTR | ENST00000541004 | ENST00000608620 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5CDS-5UTR | ENST00000541004 | ENST00000238983 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5CDS-5UTR | ENST00000541004 | ENST00000355843 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5UTR-3CDS | ENST00000495903 | ENST00000394375 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5UTR-5UTR | ENST00000495903 | ENST00000608620 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5UTR-5UTR | ENST00000495903 | ENST00000238983 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
| 5UTR-5UTR | ENST00000495903 | ENST00000355843 | ATAD1 | chr10 | 89550067 | - | LIPF | chr10 | 90427044 | + |
Top |
FusionProtFeatures for ATAD1_LIPF |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ATAD1 | LIPF |
| ATPase that plays a critical role in regulating thesurface expression of AMPA receptors (AMPAR), thereby regulatingsynaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2recycling back to the plasma membrane; these activities areATPase-dependent (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
Top |
FusionGeneSequence for ATAD1_LIPF |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ATAD1_ENST00000328142_chr10_89550067_-_LIPF_ENST00000394375_chr10_90427044_+_530aa MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDPTRKQKVEAQKQAEKLMKQIGVKNVKLSEYEMSIAAHLVDPLNMHVTW SDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGRSKMWLLLTMASLISVLGTTHGLFGKLHPGSPEVTMNISQMITYWGYPNEEY EVVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDSVEFWA FSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVPQSLFKFIFGDK IFYPHNFFDQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQAVKSGKFQAYDWGSPVQNRMHYD >In-frame_ATAD1_ENST00000400215_chr10_89550067_-_LIPF_ENST00000394375_chr10_90427044_+_472aa MKQIGVKNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGRSKMWLLLTMASLISVLGTT HGLFGKLHPGSPEVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGKKNSGNTGQRPVVFLQHGLLASATNWISNLPNNSLAFILA DAGYDVWLGNSRGNTWARRNLYYSPDSVEFWAFSFDEMAKYDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYA LAPVATVKYTKSLINKLRFVPQSLFKFIFGDKIFYPHNFFDQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTS VQNMFHWTQAVKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPKLPNLIYHKEIPFYNHLDFIW |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ATAD1_ENST00000328142_chr10_89550067_-_LIPF_ENST00000394375_chr10_90427044_+_1590nt ATGGTACATGCTGAAGCCTTTTCTCGTCCTTTGAGTCGGAATGAAGTTGTTGGTTTAATTTTCCGTTTGACAATATTTGGTGCAGTGACA TACTTTACTATCAAATGGATGGTAGATGCAATTGATCCAACCAGAAAGCAAAAAGTAGAAGCTCAGAAACAGGCAGAAAAACTAATGAAG CAAATTGGAGTGAAAAATGTGAAGCTCTCAGAATATGAAATGAGTATTGCTGCTCATCTTGTAGACCCTCTTAATATGCATGTTACTTGG AGTGATATAGCAGGTTTAGATGATGTCATTACGGATCTGAAAGACACAGTCATCTTACCTATCAAAAAGAAACATTTGTTTGAGAATTCC AGGCTTCTGCAGCCTCCAAAAGGCAGGTCCAAAATGTGGCTGCTTTTAACAATGGCAAGTTTGATATCTGTACTGGGGACTACACATGGT TTGTTTGGAAAATTACATCCTGGAAGCCCTGAAGTGACTATGAACATTAGTCAGATGATTACTTATTGGGGATACCCAAATGAAGAATAT GAAGTTGTGACTGAAGATGGTTATATTCTTGAAGTCAATAGAATTCCTTATGGGAAGAAAAATTCAGGGAATACAGGCCAGAGACCTGTT GTGTTTTTGCAGCATGGTTTGCTTGCATCAGCCACAAACTGGATTTCCAACCTGCCGAACAACAGCCTTGCCTTCATTCTGGCAGATGCT GGTTATGATGTGTGGCTGGGCAACAGCAGAGGAAACACCTGGGCCAGAAGAAACTTGTACTATTCACCAGATTCAGTTGAATTCTGGGCT TTCAGCTTTGATGAAATGGCTAAATATGACCTTCCAGCCACAATCGACTTCATTGTAAAGAAAACTGGACAGAAGCAGCTACACTATGTT GGCCATTCCCAGGGCACCACCATTGGTTTTATTGCCTTTTCCACCAATCCCAGCCTGGCTAAAAGAATCAAAACCTTCTATGCTCTAGCT CCTGTTGCCACTGTGAAGTATACAAAAAGCCTTATAAACAAACTTAGATTTGTTCCTCAATCCCTCTTCAAGTTTATATTTGGTGACAAA ATATTCTACCCACACAACTTCTTTGATCAATTTCTTGCTACTGAAGTGTGCTCCCGTGAGATGCTGAATCTCCTTTGCAGCAATGCCTTA TTTATAATTTGTGGATTTGACAGTAAGAACTTTAACACGAGTCGCTTGGATGTGTATCTATCACATAATCCAGCAGGAACTTCTGTTCAA AACATGTTCCATTGGACCCAGGCTGTTAAGTCTGGGAAATTCCAAGCTTATGACTGGGGAAGCCCAGTTCAGAATAGGATGCACTATGAT CAGTCCCAACCTCCCTACTACAATGTGACAGCCATGAATGTACCAATTGCAGTGTGGAACGGTGGCAAGGACCTGTTGGCTGACCCCCAA GATGTTGGCCTTTTGCTTCCAAAACTCCCCAATCTTATTTACCACAAGGAGATTCCTTTTTACAATCACTTGGACTTTATCTGGGCAATG >In-frame_ATAD1_ENST00000400215_chr10_89550067_-_LIPF_ENST00000394375_chr10_90427044_+_1416nt ATGAAGCAAATTGGAGTGAAAAATGTGAAGCTCTCAGAATATGAAATGAGTATTGCTGCTCATCTTGTAGACCCTCTTAATATGCATGTT ACTTGGAGTGATATAGCAGGTTTAGATGATGTCATTACGGATCTGAAAGACACAGTCATCTTACCTATCAAAAAGAAACATTTGTTTGAG AATTCCAGGCTTCTGCAGCCTCCAAAAGGCAGGTCCAAAATGTGGCTGCTTTTAACAATGGCAAGTTTGATATCTGTACTGGGGACTACA CATGGTTTGTTTGGAAAATTACATCCTGGAAGCCCTGAAGTGACTATGAACATTAGTCAGATGATTACTTATTGGGGATACCCAAATGAA GAATATGAAGTTGTGACTGAAGATGGTTATATTCTTGAAGTCAATAGAATTCCTTATGGGAAGAAAAATTCAGGGAATACAGGCCAGAGA CCTGTTGTGTTTTTGCAGCATGGTTTGCTTGCATCAGCCACAAACTGGATTTCCAACCTGCCGAACAACAGCCTTGCCTTCATTCTGGCA GATGCTGGTTATGATGTGTGGCTGGGCAACAGCAGAGGAAACACCTGGGCCAGAAGAAACTTGTACTATTCACCAGATTCAGTTGAATTC TGGGCTTTCAGCTTTGATGAAATGGCTAAATATGACCTTCCAGCCACAATCGACTTCATTGTAAAGAAAACTGGACAGAAGCAGCTACAC TATGTTGGCCATTCCCAGGGCACCACCATTGGTTTTATTGCCTTTTCCACCAATCCCAGCCTGGCTAAAAGAATCAAAACCTTCTATGCT CTAGCTCCTGTTGCCACTGTGAAGTATACAAAAAGCCTTATAAACAAACTTAGATTTGTTCCTCAATCCCTCTTCAAGTTTATATTTGGT GACAAAATATTCTACCCACACAACTTCTTTGATCAATTTCTTGCTACTGAAGTGTGCTCCCGTGAGATGCTGAATCTCCTTTGCAGCAAT GCCTTATTTATAATTTGTGGATTTGACAGTAAGAACTTTAACACGAGTCGCTTGGATGTGTATCTATCACATAATCCAGCAGGAACTTCT GTTCAAAACATGTTCCATTGGACCCAGGCTGTTAAGTCTGGGAAATTCCAAGCTTATGACTGGGGAAGCCCAGTTCAGAATAGGATGCAC TATGATCAGTCCCAACCTCCCTACTACAATGTGACAGCCATGAATGTACCAATTGCAGTGTGGAACGGTGGCAAGGACCTGTTGGCTGAC CCCCAAGATGTTGGCCTTTTGCTTCCAAAACTCCCCAATCTTATTTACCACAAGGAGATTCCTTTTTACAATCACTTGGACTTTATCTGG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ATAD1_ENST00000328142_chr10_89550067_-_LIPF_ENST00000394375_chr10_90427044_+_2003nt GTATTTTTCAAATAAAATGATTAATTCTACTACCAAATAAATCTTAATTTCTAGTCTACTTCTAGTTTGCAAGAGGAGCTTTAAATGTAT TTGTTTACTTAACATTTAAAAATCCATTTCTCCTTAAAATGAAACACTTTTTTTAAGGTAGGTAATATTTTAATTTGACTAGAAGTTAGT TTTTCTTTCTTAGTTTAAGCTACTTTGTTAGTCTTACAATTTTAATAAGTATAGTTATTACCTAGTGACATTTCTGTTTGTTTTTTTAAG GTTAACATTCAAGATGGTACATGCTGAAGCCTTTTCTCGTCCTTTGAGTCGGAATGAAGTTGTTGGTTTAATTTTCCGTTTGACAATATT TGGTGCAGTGACATACTTTACTATCAAATGGATGGTAGATGCAATTGATCCAACCAGAAAGCAAAAAGTAGAAGCTCAGAAACAGGCAGA AAAACTAATGAAGCAAATTGGAGTGAAAAATGTGAAGCTCTCAGAATATGAAATGAGTATTGCTGCTCATCTTGTAGACCCTCTTAATAT GCATGTTACTTGGAGTGATATAGCAGGTTTAGATGATGTCATTACGGATCTGAAAGACACAGTCATCTTACCTATCAAAAAGAAACATTT GTTTGAGAATTCCAGGCTTCTGCAGCCTCCAAAAGGCAGGTCCAAAATGTGGCTGCTTTTAACAATGGCAAGTTTGATATCTGTACTGGG GACTACACATGGTTTGTTTGGAAAATTACATCCTGGAAGCCCTGAAGTGACTATGAACATTAGTCAGATGATTACTTATTGGGGATACCC AAATGAAGAATATGAAGTTGTGACTGAAGATGGTTATATTCTTGAAGTCAATAGAATTCCTTATGGGAAGAAAAATTCAGGGAATACAGG CCAGAGACCTGTTGTGTTTTTGCAGCATGGTTTGCTTGCATCAGCCACAAACTGGATTTCCAACCTGCCGAACAACAGCCTTGCCTTCAT TCTGGCAGATGCTGGTTATGATGTGTGGCTGGGCAACAGCAGAGGAAACACCTGGGCCAGAAGAAACTTGTACTATTCACCAGATTCAGT TGAATTCTGGGCTTTCAGCTTTGATGAAATGGCTAAATATGACCTTCCAGCCACAATCGACTTCATTGTAAAGAAAACTGGACAGAAGCA GCTACACTATGTTGGCCATTCCCAGGGCACCACCATTGGTTTTATTGCCTTTTCCACCAATCCCAGCCTGGCTAAAAGAATCAAAACCTT CTATGCTCTAGCTCCTGTTGCCACTGTGAAGTATACAAAAAGCCTTATAAACAAACTTAGATTTGTTCCTCAATCCCTCTTCAAGTTTAT ATTTGGTGACAAAATATTCTACCCACACAACTTCTTTGATCAATTTCTTGCTACTGAAGTGTGCTCCCGTGAGATGCTGAATCTCCTTTG CAGCAATGCCTTATTTATAATTTGTGGATTTGACAGTAAGAACTTTAACACGAGTCGCTTGGATGTGTATCTATCACATAATCCAGCAGG AACTTCTGTTCAAAACATGTTCCATTGGACCCAGGCTGTTAAGTCTGGGAAATTCCAAGCTTATGACTGGGGAAGCCCAGTTCAGAATAG GATGCACTATGATCAGTCCCAACCTCCCTACTACAATGTGACAGCCATGAATGTACCAATTGCAGTGTGGAACGGTGGCAAGGACCTGTT GGCTGACCCCCAAGATGTTGGCCTTTTGCTTCCAAAACTCCCCAATCTTATTTACCACAAGGAGATTCCTTTTTACAATCACTTGGACTT TATCTGGGCAATGGATGCCCCTCAAGAAGTTTACAATGACATTGTTTCTATGATATCAGAAGATAAAAAGTAGTTCTGGATTTAAAGAAT TATCCGTTTGTTTTTCCAAAATACTTTATTCTCTCATACATAGTATTTTCATAATGTTTGACATGCAGTGCTTCTTTCTGTAATTTTGAC >In-frame_ATAD1_ENST00000400215_chr10_89550067_-_LIPF_ENST00000394375_chr10_90427044_+_1560nt AGGCAGAAAAACTAATGAAGCAAATTGGAGTGAAAAATGTGAAGCTCTCAGAATATGAAATGAGTATTGCTGCTCATCTTGTAGACCCTC TTAATATGCATGTTACTTGGAGTGATATAGCAGGTTTAGATGATGTCATTACGGATCTGAAAGACACAGTCATCTTACCTATCAAAAAGA AACATTTGTTTGAGAATTCCAGGCTTCTGCAGCCTCCAAAAGGCAGGTCCAAAATGTGGCTGCTTTTAACAATGGCAAGTTTGATATCTG TACTGGGGACTACACATGGTTTGTTTGGAAAATTACATCCTGGAAGCCCTGAAGTGACTATGAACATTAGTCAGATGATTACTTATTGGG GATACCCAAATGAAGAATATGAAGTTGTGACTGAAGATGGTTATATTCTTGAAGTCAATAGAATTCCTTATGGGAAGAAAAATTCAGGGA ATACAGGCCAGAGACCTGTTGTGTTTTTGCAGCATGGTTTGCTTGCATCAGCCACAAACTGGATTTCCAACCTGCCGAACAACAGCCTTG CCTTCATTCTGGCAGATGCTGGTTATGATGTGTGGCTGGGCAACAGCAGAGGAAACACCTGGGCCAGAAGAAACTTGTACTATTCACCAG ATTCAGTTGAATTCTGGGCTTTCAGCTTTGATGAAATGGCTAAATATGACCTTCCAGCCACAATCGACTTCATTGTAAAGAAAACTGGAC AGAAGCAGCTACACTATGTTGGCCATTCCCAGGGCACCACCATTGGTTTTATTGCCTTTTCCACCAATCCCAGCCTGGCTAAAAGAATCA AAACCTTCTATGCTCTAGCTCCTGTTGCCACTGTGAAGTATACAAAAAGCCTTATAAACAAACTTAGATTTGTTCCTCAATCCCTCTTCA AGTTTATATTTGGTGACAAAATATTCTACCCACACAACTTCTTTGATCAATTTCTTGCTACTGAAGTGTGCTCCCGTGAGATGCTGAATC TCCTTTGCAGCAATGCCTTATTTATAATTTGTGGATTTGACAGTAAGAACTTTAACACGAGTCGCTTGGATGTGTATCTATCACATAATC CAGCAGGAACTTCTGTTCAAAACATGTTCCATTGGACCCAGGCTGTTAAGTCTGGGAAATTCCAAGCTTATGACTGGGGAAGCCCAGTTC AGAATAGGATGCACTATGATCAGTCCCAACCTCCCTACTACAATGTGACAGCCATGAATGTACCAATTGCAGTGTGGAACGGTGGCAAGG ACCTGTTGGCTGACCCCCAAGATGTTGGCCTTTTGCTTCCAAAACTCCCCAATCTTATTTACCACAAGGAGATTCCTTTTTACAATCACT TGGACTTTATCTGGGCAATGGATGCCCCTCAAGAAGTTTACAATGACATTGTTTCTATGATATCAGAAGATAAAAAGTAGTTCTGGATTT AAAGAATTATCCGTTTGTTTTTCCAAAATACTTTATTCTCTCATACATAGTATTTTCATAATGTTTGACATGCAGTGCTTCTTTCTGTAA |
Top |
FusionGenePPI for ATAD1_LIPF |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ATAD1 | USP19, BABAM1, ELAVL1, PEX14, EGFR, BSCL2, FAF2, GOSR1, REV3L, VAPA, COQ9, NDUFA4, OCIAD1, TPM2, MAS1, ANKS6 | LIPF | PSEN2, ATP4A, LRSAM1, TCN2, RNF31, SHARPIN, MPZL1, BRAF, NPTX1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
RelatedDrugs for ATAD1_LIPF |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Tgene | LIPF | P07098 | DB01083 | Orlistat | Gastric triacylglycerol lipase | small molecule | approved|investigational |
Top |
RelatedDiseases for ATAD1_LIPF |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
|