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Fusion gene ID: 30084 |
FusionGeneSummary for RAB7A_TRMT1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RAB7A_TRMT1 | Fusion gene ID: 30084 | Hgene | Tgene | Gene symbol | RAB7A | TRMT1 | Gene ID | 7879 | 55687 |
| Gene name | RAB7A, member RAS oncogene family | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase | |
| Synonyms | PRO2706|RAB7 | LCAL3|MTO2|MTU1|TRMT|TRMT1 | |
| Cytomap | 3q21.3 | 22q13.31 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ras-related protein Rab-7aRAB7, member RAS oncogene familyRas-associated protein RAB7 | mitochondrial tRNA-specific 2-thiouridylase 1MTO2 homologlung cancer associated lncRNA 3mitochondrial 5-methylaminomethyl-2-thiouridylate-methyltransferase | |
| Modification date | 20180527 | 20180523 | |
| UniProtAcc | P51149 | Q9NXH9 | |
| Ensembl transtripts involved in fusion gene | ENST00000265062, ENST00000482525, ENST00000485280, | ENST00000437766, ENST00000357720, ENST00000221504, ENST00000592062, ENST00000592892, | |
| Fusion gene scores | * DoF score | 17 X 11 X 9=1683 | 2 X 2 X 2=8 |
| # samples | 18 | 2 | |
| ** MAII score | log2(18/1683*10)=-3.22496636500027 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: RAB7A [Title/Abstract] AND TRMT1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Oncogene involved fusion gene, in-frame and retained their domain. Tumor suppressor gene involved fusion gene, in-frame but not retained their domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | RAB7A | GO:0022615 | protein to membrane docking | 24344282 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | UCS | TCGA-N8-A4PP-01A | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000265062 | ENST00000437766 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| In-frame | ENST00000265062 | ENST00000357720 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| In-frame | ENST00000265062 | ENST00000221504 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| In-frame | ENST00000265062 | ENST00000592062 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| 5CDS-intron | ENST00000265062 | ENST00000592892 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| In-frame | ENST00000482525 | ENST00000437766 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| In-frame | ENST00000482525 | ENST00000357720 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| In-frame | ENST00000482525 | ENST00000221504 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| In-frame | ENST00000482525 | ENST00000592062 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| 5CDS-intron | ENST00000482525 | ENST00000592892 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| intron-3CDS | ENST00000485280 | ENST00000437766 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| intron-3CDS | ENST00000485280 | ENST00000357720 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| intron-3CDS | ENST00000485280 | ENST00000221504 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| intron-3CDS | ENST00000485280 | ENST00000592062 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
| intron-intron | ENST00000485280 | ENST00000592892 | RAB7A | chr3 | 128526514 | + | TRMT1 | chr19 | 13221120 | - |
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FusionProtFeatures for RAB7A_TRMT1 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RAB7A | TRMT1 |
| Key regulator in endo-lysosomal trafficking. Governsearly-to-late endosomal maturation, microtubule minus-end as wellas plus-end directed endosomal migration and positioning, andendosome-lysosome transport through different protein-proteininteraction cascades. Plays a central role, not only in endosomaltraffic, but also in many other cellular and physiological events,such as growth-factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport inthe axons of neurons and lipid metabolism. Also involved inregulation of some specialized endosomal membrane trafficking,such as maturation of melanosomes, pathogen-induced phagosomes (orvacuoles) and autophagosomes. Plays a role in the maturation andacidification of phagosomes that engulf pathogens, such asS.aureus and M.tuberculosis. Plays a role in the fusion ofphagosomes with lysosomes. Plays important roles in microbialpathogen infection and survival, as well as in participating inthe life cycle of viruses. Microbial pathogens possess survivalstrategies governed by RAB7A, sometimes by employing RAB7Afunction (e.g. Salmonella) and sometimes by excluding RAB7Afunction (e.g. Mycobacterium). In concert with RAC1, plays a rolein regulating the formation of RBs (ruffled borders) inosteoclasts. Controls the endosomal trafficking and neuriteoutgrowth signaling of NTRK1/TRKA (PubMed:11179213,PubMed:12944476, PubMed:14617358, PubMed:20028791,PubMed:21255211). Regulates the endocytic trafficking of the EGF-EGFR complex by regulating its lysosomal degradation. Involved inthe ADRB2-stimulated lipolysis through lipophagy, a cytosoliclipase-independent autophagic pathway (By similarity). Requiredfor the exosomal release of SDCBP, CD63 and syndecan(PubMed:22660413). {ECO:0000250|UniProtKB:P51150,ECO:0000269|PubMed:11179213, ECO:0000269|PubMed:12944476,ECO:0000269|PubMed:14617358, ECO:0000269|PubMed:20028791,ECO:0000269|PubMed:22660413}. | Dimethylates a single guanine residue at position 26 ofmost tRNAs using S-adenosyl-L-methionine as donor of the methylgroups. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | RAB7A | chr3:128526514 | chr19:13221120 | ENST00000265062 | + | 5 | 6 | 37_45 | 176 | 208 | Motif | Effector region |
| Hgene | RAB7A | chr3:128526514 | chr19:13221120 | ENST00000265062 | + | 5 | 6 | 125_128 | 176 | 208 | Nucleotide binding | GTP |
| Hgene | RAB7A | chr3:128526514 | chr19:13221120 | ENST00000265062 | + | 5 | 6 | 156_157 | 176 | 208 | Nucleotide binding | GTP |
| Hgene | RAB7A | chr3:128526514 | chr19:13221120 | ENST00000265062 | + | 5 | 6 | 15_22 | 176 | 208 | Nucleotide binding | GTP |
| Hgene | RAB7A | chr3:128526514 | chr19:13221120 | ENST00000265062 | + | 5 | 6 | 34_40 | 176 | 208 | Nucleotide binding | GTP |
| Hgene | RAB7A | chr3:128526514 | chr19:13221120 | ENST00000265062 | + | 5 | 6 | 63_67 | 176 | 208 | Nucleotide binding | GTP |
| Tgene | >TRMT1 | chr3:128526514 | chr19:13221120 | ENST00000221504 | - | 5 | 15 | 600_627 | 290 | 631 | Zinc finger | C3H1-type |
| Tgene | >TRMT1 | chr3:128526514 | chr19:13221120 | ENST00000357720 | - | 6 | 17 | 600_627 | 290 | 660 | Zinc finger | C3H1-type |
| Tgene | >TRMT1 | chr3:128526514 | chr19:13221120 | ENST00000437766 | - | 5 | 16 | 600_627 | 290 | 660 | Zinc finger | C3H1-type |
| Tgene | >TRMT1 | chr3:128526514 | chr19:13221120 | ENST00000592062 | - | 7 | 18 | 600_627 | 290 | 660 | Zinc finger | C3H1-type |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | TRMT1 | chr3:128526514 | chr19:13221120 | ENST00000221504 | - | 5 | 15 | 55_499 | 290 | 631 | Domain | Trm1 methyltransferase |
| Tgene | TRMT1 | chr3:128526514 | chr19:13221120 | ENST00000357720 | - | 6 | 17 | 55_499 | 290 | 660 | Domain | Trm1 methyltransferase |
| Tgene | TRMT1 | chr3:128526514 | chr19:13221120 | ENST00000437766 | - | 5 | 16 | 55_499 | 290 | 660 | Domain | Trm1 methyltransferase |
| Tgene | TRMT1 | chr3:128526514 | chr19:13221120 | ENST00000592062 | - | 7 | 18 | 55_499 | 290 | 660 | Domain | Trm1 methyltransferase |
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FusionGeneSequence for RAB7A_TRMT1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RAB7A_ENST00000265062_chr3_128526514_+_TRMT1_ENST00000437766_chr19_13221120_-_546aa MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDV TAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQALRI VLHSLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASASKQALVFQCVGCGAFHLQRLGKASGVPSGRAKFSAACGPPVTPEC EHCGQRHQLGGPMWAEPIHDLDFVGRVLEAVSANPGRFHTSERIRGVLSVITEELPDVPLYYTLDQLSSTIHCNTPSLLQLRSALLHADF RVSLSHACKNAVKTDAPASALWDIMRCWEKECPVKRERLSETSPAFRILSVEPRLQANFTIREDANPSSRQRGLKRFQANPEANWGPRPR ARPGGKAADEAMEERRRLLQNKRKEPPEDVAQRAARLKTFPCKRFKEGTCQRGDQCCYSHSPPTPRVSADAAPDCPETSNQTPPGPGAAA >In-frame_RAB7A_ENST00000265062_chr3_128526514_+_TRMT1_ENST00000357720_chr19_13221120_-_546aa MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDV TAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQALRI VLHSLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASASKQALVFQCVGCGAFHLQRLGKASGVPSGRAKFSAACGPPVTPEC EHCGQRHQLGGPMWAEPIHDLDFVGRVLEAVSANPGRFHTSERIRGVLSVITEELPDVPLYYTLDQLSSTIHCNTPSLLQLRSALLHADF RVSLSHACKNAVKTDAPASALWDIMRCWEKECPVKRERLSETSPAFRILSVEPRLQANFTIREDANPSSRQRGLKRFQANPEANWGPRPR ARPGGKAADEAMEERRRLLQNKRKEPPEDVAQRAARLKTFPCKRFKEGTCQRGDQCCYSHSPPTPRVSADAAPDCPETSNQTPPGPGAAA >In-frame_RAB7A_ENST00000265062_chr3_128526514_+_TRMT1_ENST00000221504_chr19_13221120_-_517aa MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDV TAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQALRI VLHSLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASARAKFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLE AVSANPGRFHTSERIRGVLSVITEELPDVPLYYTLDQLSSTIHCNTPSLLQLRSALLHADFRVSLSHACKNAVKTDAPASALWDIMRCWE KECPVKRERLSETSPAFRILSVEPRLQANFTIREDANPSSRQRGLKRFQANPEANWGPRPRARPGGKAADEAMEERRRLLQNKRKEPPED >In-frame_RAB7A_ENST00000265062_chr3_128526514_+_TRMT1_ENST00000592062_chr19_13221120_-_546aa MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDV TAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQALRI VLHSLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASASKQALVFQCVGCGAFHLQRLGKASGVPSGRAKFSAACGPPVTPEC EHCGQRHQLGGPMWAEPIHDLDFVGRVLEAVSANPGRFHTSERIRGVLSVITEELPDVPLYYTLDQLSSTIHCNTPSLLQLRSALLHADF RVSLSHACKNAVKTDAPASALWDIMRCWEKECPVKRERLSETSPAFRILSVEPRLQANFTIREDANPSSRQRGLKRFQANPEANWGPRPR ARPGGKAADEAMEERRRLLQNKRKEPPEDVAQRAARLKTFPCKRFKEGTCQRGDQCCYSHSPPTPRVSADAAPDCPETSNQTPPGPGAAA >In-frame_RAB7A_ENST00000482525_chr3_128526514_+_TRMT1_ENST00000437766_chr19_13221120_-_499aa MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVATK RAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQALRIVLHSLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASASK QALVFQCVGCGAFHLQRLGKASGVPSGRAKFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLEAVSANPGRFHTSERIRGV LSVITEELPDVPLYYTLDQLSSTIHCNTPSLLQLRSALLHADFRVSLSHACKNAVKTDAPASALWDIMRCWEKECPVKRERLSETSPAFR ILSVEPRLQANFTIREDANPSSRQRGLKRFQANPEANWGPRPRARPGGKAADEAMEERRRLLQNKRKEPPEDVAQRAARLKTFPCKRFKE >In-frame_RAB7A_ENST00000482525_chr3_128526514_+_TRMT1_ENST00000357720_chr19_13221120_-_499aa MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVATK RAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQALRIVLHSLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASASK QALVFQCVGCGAFHLQRLGKASGVPSGRAKFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLEAVSANPGRFHTSERIRGV LSVITEELPDVPLYYTLDQLSSTIHCNTPSLLQLRSALLHADFRVSLSHACKNAVKTDAPASALWDIMRCWEKECPVKRERLSETSPAFR ILSVEPRLQANFTIREDANPSSRQRGLKRFQANPEANWGPRPRARPGGKAADEAMEERRRLLQNKRKEPPEDVAQRAARLKTFPCKRFKE >In-frame_RAB7A_ENST00000482525_chr3_128526514_+_TRMT1_ENST00000221504_chr19_13221120_-_470aa MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVATK RAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQALRIVLHSLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASARA KFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLEAVSANPGRFHTSERIRGVLSVITEELPDVPLYYTLDQLSSTIHCNTP SLLQLRSALLHADFRVSLSHACKNAVKTDAPASALWDIMRCWEKECPVKRERLSETSPAFRILSVEPRLQANFTIREDANPSSRQRGLKR FQANPEANWGPRPRARPGGKAADEAMEERRRLLQNKRKEPPEDVAQRAARLKTFPCKRFKEGTCQRGDQCCYSHSPPTPRVSADAAPDCP >In-frame_RAB7A_ENST00000482525_chr3_128526514_+_TRMT1_ENST00000592062_chr19_13221120_-_499aa MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVATK RAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQALRIVLHSLDLRANCYQRFVVPLLSISADFYVRVFVRVFTGQAKVKASASK QALVFQCVGCGAFHLQRLGKASGVPSGRAKFSAACGPPVTPECEHCGQRHQLGGPMWAEPIHDLDFVGRVLEAVSANPGRFHTSERIRGV LSVITEELPDVPLYYTLDQLSSTIHCNTPSLLQLRSALLHADFRVSLSHACKNAVKTDAPASALWDIMRCWEKECPVKRERLSETSPAFR ILSVEPRLQANFTIREDANPSSRQRGLKRFQANPEANWGPRPRARPGGKAADEAMEERRRLLQNKRKEPPEDVAQRAARLKTFPCKRFKE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RAB7A_ENST00000265062_chr3_128526514_+_TRMT1_ENST00000437766_chr19_13221120_-_1638nt ATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAAT AAGAAATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAG ATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTATTTGATGTG ACTGCCCCCAACACATTCAAAACCCTAGATAGCTGGAGAGATGAGTTTCTCATCCAGGCCAGTCCCCGAGATCCTGAAAACTTCCCATTT GTTGTGTTGGGAAACAAGATTGACCTCGAAAACAGACAAGTGGCCACAAAGCGGGCACAGGCCTGGTGCTACAGCAAAAACAACATTCCC TACTTTGAGACCAGTGCCAAGGAGGCCATCAACGTGGAGCAGGCGTTCCAGACGATTGCACGGAATGCACTTAAGCAGGCCCTGAGAATC GTCCTGCACAGCCTGGACCTCCGCGCCAACTGCTACCAGCGCTTCGTGGTGCCGCTGCTCAGCATCAGCGCTGACTTCTACGTGCGTGTT TTTGTCCGTGTCTTCACCGGCCAGGCCAAGGTCAAGGCCTCAGCCAGCAAGCAGGCGCTGGTGTTCCAGTGTGTGGGCTGCGGGGCCTTC CACCTTCAGCGTCTCGGCAAAGCGTCAGGAGTCCCCAGCGGCCGGGCCAAGTTCTCTGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGT GAACACTGTGGGCAACGACACCAGCTTGGTGGCCCCATGTGGGCAGAGCCCATCCATGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCT GTGAGCGCTAACCCCGGCCGCTTCCACACCTCGGAGCGGATCCGAGGGGTCCTGAGCGTCATCACTGAGGAGCTCCCGGACGTGCCTCTG TACTACACCCTGGACCAGCTGAGCAGCACCATCCACTGCAACACACCAAGCCTCCTGCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTC CGGGTCTCACTCTCCCACGCCTGTAAGAACGCTGTGAAGACGGATGCCCCTGCCTCTGCCCTCTGGGACATCATGCGTTGCTGGGAGAAG GAATGTCCGGTGAAACGGGAGCGACTATCAGAGACTAGCCCAGCGTTCCGCATTCTCAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACC ATCCGGGAAGATGCCAACCCCAGCTCCCGACAGCGAGGACTCAAGCGCTTCCAGGCTAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGT GCCCGGCCAGGGGGCAAGGCGGCCGACGAAGCTATGGAGGAGAGACGCAGGCTGCTTCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTG GCCCAGCGGGCTGCCCGGCTCAAGACATTTCCTTGCAAGAGGTTTAAGGAGGGCACCTGTCAACGCGGGGACCAGTGCTGCTACTCCCAC AGCCCCCCGACACCCAGGGTTTCTGCTGATGCTGCCCCTGACTGTCCAGAGACCTCCAACCAGACCCCCCCTGGACCTGGGGCTGCCGCT >In-frame_RAB7A_ENST00000265062_chr3_128526514_+_TRMT1_ENST00000357720_chr19_13221120_-_1638nt ATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAAT AAGAAATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAG ATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTATTTGATGTG ACTGCCCCCAACACATTCAAAACCCTAGATAGCTGGAGAGATGAGTTTCTCATCCAGGCCAGTCCCCGAGATCCTGAAAACTTCCCATTT GTTGTGTTGGGAAACAAGATTGACCTCGAAAACAGACAAGTGGCCACAAAGCGGGCACAGGCCTGGTGCTACAGCAAAAACAACATTCCC TACTTTGAGACCAGTGCCAAGGAGGCCATCAACGTGGAGCAGGCGTTCCAGACGATTGCACGGAATGCACTTAAGCAGGCCCTGAGAATC GTCCTGCACAGCCTGGACCTCCGCGCCAACTGCTACCAGCGCTTCGTGGTGCCGCTGCTCAGCATCAGCGCTGACTTCTACGTGCGTGTT TTTGTCCGTGTCTTCACCGGCCAGGCCAAGGTCAAGGCCTCAGCCAGCAAGCAGGCGCTGGTGTTCCAGTGTGTGGGCTGCGGGGCCTTC CACCTTCAGCGTCTCGGCAAAGCGTCAGGAGTCCCCAGCGGCCGGGCCAAGTTCTCTGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGT GAACACTGTGGGCAACGACACCAGCTTGGTGGCCCCATGTGGGCAGAGCCCATCCATGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCT GTGAGCGCTAACCCCGGCCGCTTCCACACCTCGGAGCGGATCCGAGGGGTCCTGAGCGTCATCACTGAGGAGCTCCCGGACGTGCCTCTG TACTACACCCTGGACCAGCTGAGCAGCACCATCCACTGCAACACACCAAGCCTCCTGCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTC CGGGTCTCACTCTCCCACGCCTGTAAGAACGCTGTGAAGACGGATGCCCCTGCCTCTGCCCTCTGGGACATCATGCGTTGCTGGGAGAAG GAATGTCCGGTGAAACGGGAGCGACTATCAGAGACTAGCCCAGCGTTCCGCATTCTCAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACC ATCCGGGAAGATGCCAACCCCAGCTCCCGACAGCGAGGACTCAAGCGCTTCCAGGCTAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGT GCCCGGCCAGGGGGCAAGGCGGCCGACGAAGCTATGGAGGAGAGACGCAGGCTGCTTCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTG GCCCAGCGGGCTGCCCGGCTCAAGACATTTCCTTGCAAGAGGTTTAAGGAGGGCACCTGTCAACGCGGGGACCAGTGCTGCTACTCCCAC AGCCCCCCGACACCCAGGGTTTCTGCTGATGCTGCCCCTGACTGTCCAGAGACCTCCAACCAGACCCCCCCTGGACCTGGGGCTGCCGCT >In-frame_RAB7A_ENST00000265062_chr3_128526514_+_TRMT1_ENST00000221504_chr19_13221120_-_1551nt ATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAAT AAGAAATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAG ATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTATTTGATGTG ACTGCCCCCAACACATTCAAAACCCTAGATAGCTGGAGAGATGAGTTTCTCATCCAGGCCAGTCCCCGAGATCCTGAAAACTTCCCATTT GTTGTGTTGGGAAACAAGATTGACCTCGAAAACAGACAAGTGGCCACAAAGCGGGCACAGGCCTGGTGCTACAGCAAAAACAACATTCCC TACTTTGAGACCAGTGCCAAGGAGGCCATCAACGTGGAGCAGGCGTTCCAGACGATTGCACGGAATGCACTTAAGCAGGCCCTGAGAATC GTCCTGCACAGCCTGGACCTCCGCGCCAACTGCTACCAGCGCTTCGTGGTGCCGCTGCTCAGCATCAGCGCTGACTTCTACGTGCGTGTT TTTGTCCGTGTCTTCACCGGCCAGGCCAAGGTCAAGGCCTCAGCCAGGGCCAAGTTCTCTGCAGCCTGTGGTCCCCCTGTGACCCCCGAG TGTGAACACTGTGGGCAACGACACCAGCTTGGTGGCCCCATGTGGGCAGAGCCCATCCATGACCTGGATTTTGTGGGCCGTGTCCTGGAG GCTGTGAGCGCTAACCCCGGCCGCTTCCACACCTCGGAGCGGATCCGAGGGGTCCTGAGCGTCATCACTGAGGAGCTCCCGGACGTGCCT CTGTACTACACCCTGGACCAGCTGAGCAGCACCATCCACTGCAACACACCAAGCCTCCTGCAGTTGCGGTCGGCCCTCCTCCACGCTGAC TTCCGGGTCTCACTCTCCCACGCCTGTAAGAACGCTGTGAAGACGGATGCCCCTGCCTCTGCCCTCTGGGACATCATGCGTTGCTGGGAG AAGGAATGTCCGGTGAAACGGGAGCGACTATCAGAGACTAGCCCAGCGTTCCGCATTCTCAGTGTGGAGCCCAGGCTGCAGGCCAACTTC ACCATCCGGGAAGATGCCAACCCCAGCTCCCGACAGCGAGGACTCAAGCGCTTCCAGGCTAACCCGGAGGCCAACTGGGGTCCCCGGCCT CGTGCCCGGCCAGGGGGCAAGGCGGCCGACGAAGCTATGGAGGAGAGACGCAGGCTGCTTCAGAACAAGCGGAAGGAGCCGCCGGAAGAT GTGGCCCAGCGGGCTGCCCGGCTCAAGACATTTCCTTGCAAGAGGTTTAAGGAGGGCACCTGTCAACGCGGGGACCAGTGCTGCTACTCC CACAGCCCCCCGACACCCAGGGTTTCTGCTGATGCTGCCCCTGACTGTCCAGAGACCTCCAACCAGACCCCCCCTGGACCTGGGGCTGCC >In-frame_RAB7A_ENST00000265062_chr3_128526514_+_TRMT1_ENST00000592062_chr19_13221120_-_1638nt ATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAAT AAGAAATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAG ATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTATTTGATGTG ACTGCCCCCAACACATTCAAAACCCTAGATAGCTGGAGAGATGAGTTTCTCATCCAGGCCAGTCCCCGAGATCCTGAAAACTTCCCATTT GTTGTGTTGGGAAACAAGATTGACCTCGAAAACAGACAAGTGGCCACAAAGCGGGCACAGGCCTGGTGCTACAGCAAAAACAACATTCCC TACTTTGAGACCAGTGCCAAGGAGGCCATCAACGTGGAGCAGGCGTTCCAGACGATTGCACGGAATGCACTTAAGCAGGCCCTGAGAATC GTCCTGCACAGCCTGGACCTCCGCGCCAACTGCTACCAGCGCTTCGTGGTGCCGCTGCTCAGCATCAGCGCTGACTTCTACGTGCGTGTT TTTGTCCGTGTCTTCACCGGCCAGGCCAAGGTCAAGGCCTCAGCCAGCAAGCAGGCGCTGGTGTTCCAGTGTGTGGGCTGCGGGGCCTTC CACCTTCAGCGTCTCGGCAAAGCGTCAGGAGTCCCCAGCGGCCGGGCCAAGTTCTCTGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGT GAACACTGTGGGCAACGACACCAGCTTGGTGGCCCCATGTGGGCAGAGCCCATCCATGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCT GTGAGCGCTAACCCCGGCCGCTTCCACACCTCGGAGCGGATCCGAGGGGTCCTGAGCGTCATCACTGAGGAGCTCCCGGACGTGCCTCTG TACTACACCCTGGACCAGCTGAGCAGCACCATCCACTGCAACACACCAAGCCTCCTGCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTC CGGGTCTCACTCTCCCACGCCTGTAAGAACGCTGTGAAGACGGATGCCCCTGCCTCTGCCCTCTGGGACATCATGCGTTGCTGGGAGAAG GAATGTCCGGTGAAACGGGAGCGACTATCAGAGACTAGCCCAGCGTTCCGCATTCTCAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACC ATCCGGGAAGATGCCAACCCCAGCTCCCGACAGCGAGGACTCAAGCGCTTCCAGGCTAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGT GCCCGGCCAGGGGGCAAGGCGGCCGACGAAGCTATGGAGGAGAGACGCAGGCTGCTTCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTG GCCCAGCGGGCTGCCCGGCTCAAGACATTTCCTTGCAAGAGGTTTAAGGAGGGCACCTGTCAACGCGGGGACCAGTGCTGCTACTCCCAC AGCCCCCCGACACCCAGGGTTTCTGCTGATGCTGCCCCTGACTGTCCAGAGACCTCCAACCAGACCCCCCCTGGACCTGGGGCTGCCGCT >In-frame_RAB7A_ENST00000482525_chr3_128526514_+_TRMT1_ENST00000437766_chr19_13221120_-_1497nt ATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAAT AAGAAATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAG ATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTGGCCACAAAG CGGGCACAGGCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAGGCCATCAACGTGGAGCAGGCGTTCCAG ACGATTGCACGGAATGCACTTAAGCAGGCCCTGAGAATCGTCCTGCACAGCCTGGACCTCCGCGCCAACTGCTACCAGCGCTTCGTGGTG CCGCTGCTCAGCATCAGCGCTGACTTCTACGTGCGTGTTTTTGTCCGTGTCTTCACCGGCCAGGCCAAGGTCAAGGCCTCAGCCAGCAAG CAGGCGCTGGTGTTCCAGTGTGTGGGCTGCGGGGCCTTCCACCTTCAGCGTCTCGGCAAAGCGTCAGGAGTCCCCAGCGGCCGGGCCAAG TTCTCTGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGTGAACACTGTGGGCAACGACACCAGCTTGGTGGCCCCATGTGGGCAGAGCCC ATCCATGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCTGTGAGCGCTAACCCCGGCCGCTTCCACACCTCGGAGCGGATCCGAGGGGTC CTGAGCGTCATCACTGAGGAGCTCCCGGACGTGCCTCTGTACTACACCCTGGACCAGCTGAGCAGCACCATCCACTGCAACACACCAAGC CTCCTGCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTCCGGGTCTCACTCTCCCACGCCTGTAAGAACGCTGTGAAGACGGATGCCCCT GCCTCTGCCCTCTGGGACATCATGCGTTGCTGGGAGAAGGAATGTCCGGTGAAACGGGAGCGACTATCAGAGACTAGCCCAGCGTTCCGC ATTCTCAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACCATCCGGGAAGATGCCAACCCCAGCTCCCGACAGCGAGGACTCAAGCGCTTC CAGGCTAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGTGCCCGGCCAGGGGGCAAGGCGGCCGACGAAGCTATGGAGGAGAGACGCAGG CTGCTTCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTGGCCCAGCGGGCTGCCCGGCTCAAGACATTTCCTTGCAAGAGGTTTAAGGAG GGCACCTGTCAACGCGGGGACCAGTGCTGCTACTCCCACAGCCCCCCGACACCCAGGGTTTCTGCTGATGCTGCCCCTGACTGTCCAGAG >In-frame_RAB7A_ENST00000482525_chr3_128526514_+_TRMT1_ENST00000357720_chr19_13221120_-_1497nt ATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAAT AAGAAATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAG ATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTGGCCACAAAG CGGGCACAGGCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAGGCCATCAACGTGGAGCAGGCGTTCCAG ACGATTGCACGGAATGCACTTAAGCAGGCCCTGAGAATCGTCCTGCACAGCCTGGACCTCCGCGCCAACTGCTACCAGCGCTTCGTGGTG CCGCTGCTCAGCATCAGCGCTGACTTCTACGTGCGTGTTTTTGTCCGTGTCTTCACCGGCCAGGCCAAGGTCAAGGCCTCAGCCAGCAAG CAGGCGCTGGTGTTCCAGTGTGTGGGCTGCGGGGCCTTCCACCTTCAGCGTCTCGGCAAAGCGTCAGGAGTCCCCAGCGGCCGGGCCAAG TTCTCTGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGTGAACACTGTGGGCAACGACACCAGCTTGGTGGCCCCATGTGGGCAGAGCCC ATCCATGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCTGTGAGCGCTAACCCCGGCCGCTTCCACACCTCGGAGCGGATCCGAGGGGTC CTGAGCGTCATCACTGAGGAGCTCCCGGACGTGCCTCTGTACTACACCCTGGACCAGCTGAGCAGCACCATCCACTGCAACACACCAAGC CTCCTGCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTCCGGGTCTCACTCTCCCACGCCTGTAAGAACGCTGTGAAGACGGATGCCCCT GCCTCTGCCCTCTGGGACATCATGCGTTGCTGGGAGAAGGAATGTCCGGTGAAACGGGAGCGACTATCAGAGACTAGCCCAGCGTTCCGC ATTCTCAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACCATCCGGGAAGATGCCAACCCCAGCTCCCGACAGCGAGGACTCAAGCGCTTC CAGGCTAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGTGCCCGGCCAGGGGGCAAGGCGGCCGACGAAGCTATGGAGGAGAGACGCAGG CTGCTTCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTGGCCCAGCGGGCTGCCCGGCTCAAGACATTTCCTTGCAAGAGGTTTAAGGAG GGCACCTGTCAACGCGGGGACCAGTGCTGCTACTCCCACAGCCCCCCGACACCCAGGGTTTCTGCTGATGCTGCCCCTGACTGTCCAGAG >In-frame_RAB7A_ENST00000482525_chr3_128526514_+_TRMT1_ENST00000221504_chr19_13221120_-_1410nt ATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAAT AAGAAATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAG ATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTGGCCACAAAG CGGGCACAGGCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAGGCCATCAACGTGGAGCAGGCGTTCCAG ACGATTGCACGGAATGCACTTAAGCAGGCCCTGAGAATCGTCCTGCACAGCCTGGACCTCCGCGCCAACTGCTACCAGCGCTTCGTGGTG CCGCTGCTCAGCATCAGCGCTGACTTCTACGTGCGTGTTTTTGTCCGTGTCTTCACCGGCCAGGCCAAGGTCAAGGCCTCAGCCAGGGCC AAGTTCTCTGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGTGAACACTGTGGGCAACGACACCAGCTTGGTGGCCCCATGTGGGCAGAG CCCATCCATGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCTGTGAGCGCTAACCCCGGCCGCTTCCACACCTCGGAGCGGATCCGAGGG GTCCTGAGCGTCATCACTGAGGAGCTCCCGGACGTGCCTCTGTACTACACCCTGGACCAGCTGAGCAGCACCATCCACTGCAACACACCA AGCCTCCTGCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTCCGGGTCTCACTCTCCCACGCCTGTAAGAACGCTGTGAAGACGGATGCC CCTGCCTCTGCCCTCTGGGACATCATGCGTTGCTGGGAGAAGGAATGTCCGGTGAAACGGGAGCGACTATCAGAGACTAGCCCAGCGTTC CGCATTCTCAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACCATCCGGGAAGATGCCAACCCCAGCTCCCGACAGCGAGGACTCAAGCGC TTCCAGGCTAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGTGCCCGGCCAGGGGGCAAGGCGGCCGACGAAGCTATGGAGGAGAGACGC AGGCTGCTTCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTGGCCCAGCGGGCTGCCCGGCTCAAGACATTTCCTTGCAAGAGGTTTAAG GAGGGCACCTGTCAACGCGGGGACCAGTGCTGCTACTCCCACAGCCCCCCGACACCCAGGGTTTCTGCTGATGCTGCCCCTGACTGTCCA >In-frame_RAB7A_ENST00000482525_chr3_128526514_+_TRMT1_ENST00000592062_chr19_13221120_-_1497nt ATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAAT AAGAAATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAG ATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTGGCCACAAAG CGGGCACAGGCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAGGCCATCAACGTGGAGCAGGCGTTCCAG ACGATTGCACGGAATGCACTTAAGCAGGCCCTGAGAATCGTCCTGCACAGCCTGGACCTCCGCGCCAACTGCTACCAGCGCTTCGTGGTG CCGCTGCTCAGCATCAGCGCTGACTTCTACGTGCGTGTTTTTGTCCGTGTCTTCACCGGCCAGGCCAAGGTCAAGGCCTCAGCCAGCAAG CAGGCGCTGGTGTTCCAGTGTGTGGGCTGCGGGGCCTTCCACCTTCAGCGTCTCGGCAAAGCGTCAGGAGTCCCCAGCGGCCGGGCCAAG TTCTCTGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGTGAACACTGTGGGCAACGACACCAGCTTGGTGGCCCCATGTGGGCAGAGCCC ATCCATGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCTGTGAGCGCTAACCCCGGCCGCTTCCACACCTCGGAGCGGATCCGAGGGGTC CTGAGCGTCATCACTGAGGAGCTCCCGGACGTGCCTCTGTACTACACCCTGGACCAGCTGAGCAGCACCATCCACTGCAACACACCAAGC CTCCTGCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTCCGGGTCTCACTCTCCCACGCCTGTAAGAACGCTGTGAAGACGGATGCCCCT GCCTCTGCCCTCTGGGACATCATGCGTTGCTGGGAGAAGGAATGTCCGGTGAAACGGGAGCGACTATCAGAGACTAGCCCAGCGTTCCGC ATTCTCAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACCATCCGGGAAGATGCCAACCCCAGCTCCCGACAGCGAGGACTCAAGCGCTTC CAGGCTAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGTGCCCGGCCAGGGGGCAAGGCGGCCGACGAAGCTATGGAGGAGAGACGCAGG CTGCTTCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTGGCCCAGCGGGCTGCCCGGCTCAAGACATTTCCTTGCAAGAGGTTTAAGGAG GGCACCTGTCAACGCGGGGACCAGTGCTGCTACTCCCACAGCCCCCCGACACCCAGGGTTTCTGCTGATGCTGCCCCTGACTGTCCAGAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RAB7A_ENST00000265062_chr3_128526514_+_TRMT1_ENST00000437766_chr19_13221120_-_1917nt GTCTCGTGACAGGTACTTCCGCTCGGGGCGGCGGCGGTGGCGGAAGTGGGAGCGGGCCTGGAGTCTTGGCCATAAAGCCTGAGGCGGCGG CAGCGGCGGAGTTGGCGGCTTGGAGAGCTCGGGAGAGTTCCCTGGAACCAGAACTTGGACCTTCTCGCTTCTGTCCTCCGTTTAGTCTCC TCCTCGGCGGGAGCCCTCGCGACGCGCCCGGCCCGGAGCCCCCAGCGCAGCGGCCGCGTTTGAAGGATGACCTCTAGGAAGAAAGTGTTG CTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAATAAGAAATTCAGCAATCAGTACAAA GCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAGATATGGGACACAGCAGGACAGGAA CGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTATTTGATGTGACTGCCCCCAACACATTCAAAACC CTAGATAGCTGGAGAGATGAGTTTCTCATCCAGGCCAGTCCCCGAGATCCTGAAAACTTCCCATTTGTTGTGTTGGGAAACAAGATTGAC CTCGAAAACAGACAAGTGGCCACAAAGCGGGCACAGGCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAG GCCATCAACGTGGAGCAGGCGTTCCAGACGATTGCACGGAATGCACTTAAGCAGGCCCTGAGAATCGTCCTGCACAGCCTGGACCTCCGC GCCAACTGCTACCAGCGCTTCGTGGTGCCGCTGCTCAGCATCAGCGCTGACTTCTACGTGCGTGTTTTTGTCCGTGTCTTCACCGGCCAG GCCAAGGTCAAGGCCTCAGCCAGCAAGCAGGCGCTGGTGTTCCAGTGTGTGGGCTGCGGGGCCTTCCACCTTCAGCGTCTCGGCAAAGCG TCAGGAGTCCCCAGCGGCCGGGCCAAGTTCTCTGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGTGAACACTGTGGGCAACGACACCAG CTTGGTGGCCCCATGTGGGCAGAGCCCATCCATGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCTGTGAGCGCTAACCCCGGCCGCTTC CACACCTCGGAGCGGATCCGAGGGGTCCTGAGCGTCATCACTGAGGAGCTCCCGGACGTGCCTCTGTACTACACCCTGGACCAGCTGAGC AGCACCATCCACTGCAACACACCAAGCCTCCTGCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTCCGGGTCTCACTCTCCCACGCCTGT AAGAACGCTGTGAAGACGGATGCCCCTGCCTCTGCCCTCTGGGACATCATGCGTTGCTGGGAGAAGGAATGTCCGGTGAAACGGGAGCGA CTATCAGAGACTAGCCCAGCGTTCCGCATTCTCAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACCATCCGGGAAGATGCCAACCCCAGC TCCCGACAGCGAGGACTCAAGCGCTTCCAGGCTAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGTGCCCGGCCAGGGGGCAAGGCGGCC GACGAAGCTATGGAGGAGAGACGCAGGCTGCTTCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTGGCCCAGCGGGCTGCCCGGCTCAAG ACATTTCCTTGCAAGAGGTTTAAGGAGGGCACCTGTCAACGCGGGGACCAGTGCTGCTACTCCCACAGCCCCCCGACACCCAGGGTTTCT GCTGATGCTGCCCCTGACTGTCCAGAGACCTCCAACCAGACCCCCCCTGGACCTGGGGCTGCCGCTGGGCCAGGCATAGACTGAACCAAT >In-frame_RAB7A_ENST00000265062_chr3_128526514_+_TRMT1_ENST00000357720_chr19_13221120_-_1917nt GTCTCGTGACAGGTACTTCCGCTCGGGGCGGCGGCGGTGGCGGAAGTGGGAGCGGGCCTGGAGTCTTGGCCATAAAGCCTGAGGCGGCGG CAGCGGCGGAGTTGGCGGCTTGGAGAGCTCGGGAGAGTTCCCTGGAACCAGAACTTGGACCTTCTCGCTTCTGTCCTCCGTTTAGTCTCC TCCTCGGCGGGAGCCCTCGCGACGCGCCCGGCCCGGAGCCCCCAGCGCAGCGGCCGCGTTTGAAGGATGACCTCTAGGAAGAAAGTGTTG CTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAATAAGAAATTCAGCAATCAGTACAAA GCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAGATATGGGACACAGCAGGACAGGAA CGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTATTTGATGTGACTGCCCCCAACACATTCAAAACC CTAGATAGCTGGAGAGATGAGTTTCTCATCCAGGCCAGTCCCCGAGATCCTGAAAACTTCCCATTTGTTGTGTTGGGAAACAAGATTGAC CTCGAAAACAGACAAGTGGCCACAAAGCGGGCACAGGCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAG GCCATCAACGTGGAGCAGGCGTTCCAGACGATTGCACGGAATGCACTTAAGCAGGCCCTGAGAATCGTCCTGCACAGCCTGGACCTCCGC GCCAACTGCTACCAGCGCTTCGTGGTGCCGCTGCTCAGCATCAGCGCTGACTTCTACGTGCGTGTTTTTGTCCGTGTCTTCACCGGCCAG GCCAAGGTCAAGGCCTCAGCCAGCAAGCAGGCGCTGGTGTTCCAGTGTGTGGGCTGCGGGGCCTTCCACCTTCAGCGTCTCGGCAAAGCG TCAGGAGTCCCCAGCGGCCGGGCCAAGTTCTCTGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGTGAACACTGTGGGCAACGACACCAG CTTGGTGGCCCCATGTGGGCAGAGCCCATCCATGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCTGTGAGCGCTAACCCCGGCCGCTTC CACACCTCGGAGCGGATCCGAGGGGTCCTGAGCGTCATCACTGAGGAGCTCCCGGACGTGCCTCTGTACTACACCCTGGACCAGCTGAGC AGCACCATCCACTGCAACACACCAAGCCTCCTGCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTCCGGGTCTCACTCTCCCACGCCTGT AAGAACGCTGTGAAGACGGATGCCCCTGCCTCTGCCCTCTGGGACATCATGCGTTGCTGGGAGAAGGAATGTCCGGTGAAACGGGAGCGA CTATCAGAGACTAGCCCAGCGTTCCGCATTCTCAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACCATCCGGGAAGATGCCAACCCCAGC TCCCGACAGCGAGGACTCAAGCGCTTCCAGGCTAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGTGCCCGGCCAGGGGGCAAGGCGGCC GACGAAGCTATGGAGGAGAGACGCAGGCTGCTTCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTGGCCCAGCGGGCTGCCCGGCTCAAG ACATTTCCTTGCAAGAGGTTTAAGGAGGGCACCTGTCAACGCGGGGACCAGTGCTGCTACTCCCACAGCCCCCCGACACCCAGGGTTTCT GCTGATGCTGCCCCTGACTGTCCAGAGACCTCCAACCAGACCCCCCCTGGACCTGGGGCTGCCGCTGGGCCAGGCATAGACTGAACCAAT >In-frame_RAB7A_ENST00000265062_chr3_128526514_+_TRMT1_ENST00000221504_chr19_13221120_-_1825nt GTCTCGTGACAGGTACTTCCGCTCGGGGCGGCGGCGGTGGCGGAAGTGGGAGCGGGCCTGGAGTCTTGGCCATAAAGCCTGAGGCGGCGG CAGCGGCGGAGTTGGCGGCTTGGAGAGCTCGGGAGAGTTCCCTGGAACCAGAACTTGGACCTTCTCGCTTCTGTCCTCCGTTTAGTCTCC TCCTCGGCGGGAGCCCTCGCGACGCGCCCGGCCCGGAGCCCCCAGCGCAGCGGCCGCGTTTGAAGGATGACCTCTAGGAAGAAAGTGTTG CTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAATAAGAAATTCAGCAATCAGTACAAA GCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAGATATGGGACACAGCAGGACAGGAA CGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTATTTGATGTGACTGCCCCCAACACATTCAAAACC CTAGATAGCTGGAGAGATGAGTTTCTCATCCAGGCCAGTCCCCGAGATCCTGAAAACTTCCCATTTGTTGTGTTGGGAAACAAGATTGAC CTCGAAAACAGACAAGTGGCCACAAAGCGGGCACAGGCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAG GCCATCAACGTGGAGCAGGCGTTCCAGACGATTGCACGGAATGCACTTAAGCAGGCCCTGAGAATCGTCCTGCACAGCCTGGACCTCCGC GCCAACTGCTACCAGCGCTTCGTGGTGCCGCTGCTCAGCATCAGCGCTGACTTCTACGTGCGTGTTTTTGTCCGTGTCTTCACCGGCCAG GCCAAGGTCAAGGCCTCAGCCAGGGCCAAGTTCTCTGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGTGAACACTGTGGGCAACGACAC CAGCTTGGTGGCCCCATGTGGGCAGAGCCCATCCATGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCTGTGAGCGCTAACCCCGGCCGC TTCCACACCTCGGAGCGGATCCGAGGGGTCCTGAGCGTCATCACTGAGGAGCTCCCGGACGTGCCTCTGTACTACACCCTGGACCAGCTG AGCAGCACCATCCACTGCAACACACCAAGCCTCCTGCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTCCGGGTCTCACTCTCCCACGCC TGTAAGAACGCTGTGAAGACGGATGCCCCTGCCTCTGCCCTCTGGGACATCATGCGTTGCTGGGAGAAGGAATGTCCGGTGAAACGGGAG CGACTATCAGAGACTAGCCCAGCGTTCCGCATTCTCAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACCATCCGGGAAGATGCCAACCCC AGCTCCCGACAGCGAGGACTCAAGCGCTTCCAGGCTAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGTGCCCGGCCAGGGGGCAAGGCG GCCGACGAAGCTATGGAGGAGAGACGCAGGCTGCTTCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTGGCCCAGCGGGCTGCCCGGCTC AAGACATTTCCTTGCAAGAGGTTTAAGGAGGGCACCTGTCAACGCGGGGACCAGTGCTGCTACTCCCACAGCCCCCCGACACCCAGGGTT TCTGCTGATGCTGCCCCTGACTGTCCAGAGACCTCCAACCAGACCCCCCCTGGACCTGGGGCTGCCGCTGGGCCAGGCATAGACTGAACC >In-frame_RAB7A_ENST00000265062_chr3_128526514_+_TRMT1_ENST00000592062_chr19_13221120_-_1912nt GTCTCGTGACAGGTACTTCCGCTCGGGGCGGCGGCGGTGGCGGAAGTGGGAGCGGGCCTGGAGTCTTGGCCATAAAGCCTGAGGCGGCGG CAGCGGCGGAGTTGGCGGCTTGGAGAGCTCGGGAGAGTTCCCTGGAACCAGAACTTGGACCTTCTCGCTTCTGTCCTCCGTTTAGTCTCC TCCTCGGCGGGAGCCCTCGCGACGCGCCCGGCCCGGAGCCCCCAGCGCAGCGGCCGCGTTTGAAGGATGACCTCTAGGAAGAAAGTGTTG CTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAATAAGAAATTCAGCAATCAGTACAAA GCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAGATATGGGACACAGCAGGACAGGAA CGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTATTTGATGTGACTGCCCCCAACACATTCAAAACC CTAGATAGCTGGAGAGATGAGTTTCTCATCCAGGCCAGTCCCCGAGATCCTGAAAACTTCCCATTTGTTGTGTTGGGAAACAAGATTGAC CTCGAAAACAGACAAGTGGCCACAAAGCGGGCACAGGCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAG GCCATCAACGTGGAGCAGGCGTTCCAGACGATTGCACGGAATGCACTTAAGCAGGCCCTGAGAATCGTCCTGCACAGCCTGGACCTCCGC GCCAACTGCTACCAGCGCTTCGTGGTGCCGCTGCTCAGCATCAGCGCTGACTTCTACGTGCGTGTTTTTGTCCGTGTCTTCACCGGCCAG GCCAAGGTCAAGGCCTCAGCCAGCAAGCAGGCGCTGGTGTTCCAGTGTGTGGGCTGCGGGGCCTTCCACCTTCAGCGTCTCGGCAAAGCG TCAGGAGTCCCCAGCGGCCGGGCCAAGTTCTCTGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGTGAACACTGTGGGCAACGACACCAG CTTGGTGGCCCCATGTGGGCAGAGCCCATCCATGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCTGTGAGCGCTAACCCCGGCCGCTTC CACACCTCGGAGCGGATCCGAGGGGTCCTGAGCGTCATCACTGAGGAGCTCCCGGACGTGCCTCTGTACTACACCCTGGACCAGCTGAGC AGCACCATCCACTGCAACACACCAAGCCTCCTGCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTCCGGGTCTCACTCTCCCACGCCTGT AAGAACGCTGTGAAGACGGATGCCCCTGCCTCTGCCCTCTGGGACATCATGCGTTGCTGGGAGAAGGAATGTCCGGTGAAACGGGAGCGA CTATCAGAGACTAGCCCAGCGTTCCGCATTCTCAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACCATCCGGGAAGATGCCAACCCCAGC TCCCGACAGCGAGGACTCAAGCGCTTCCAGGCTAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGTGCCCGGCCAGGGGGCAAGGCGGCC GACGAAGCTATGGAGGAGAGACGCAGGCTGCTTCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTGGCCCAGCGGGCTGCCCGGCTCAAG ACATTTCCTTGCAAGAGGTTTAAGGAGGGCACCTGTCAACGCGGGGACCAGTGCTGCTACTCCCACAGCCCCCCGACACCCAGGGTTTCT GCTGATGCTGCCCCTGACTGTCCAGAGACCTCCAACCAGACCCCCCCTGGACCTGGGGCTGCCGCTGGGCCAGGCATAGACTGAACCAAT >In-frame_RAB7A_ENST00000482525_chr3_128526514_+_TRMT1_ENST00000437766_chr19_13221120_-_1705nt ATAAAGCCTGAGGCGGCGGCAGCGGCGGAGTTGGCGGCTTGGAGAGCTCGGGAGAGTTCCCTGGAACCAGAACTTGGACCTTCTCGCTTC TGTCCTCCGTTTAGTCTCCTCCTCGGCGGGAGCCCTCGCGACGCGCCCGGCCCGGAGCCCCCAGCGCAGCGGCCGCGTTTGAAGGATGAC CTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAATAAGAA ATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAGATATG GGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTGGCCACAAAGCGGGC ACAGGCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAGGCCATCAACGTGGAGCAGGCGTTCCAGACGAT TGCACGGAATGCACTTAAGCAGGCCCTGAGAATCGTCCTGCACAGCCTGGACCTCCGCGCCAACTGCTACCAGCGCTTCGTGGTGCCGCT GCTCAGCATCAGCGCTGACTTCTACGTGCGTGTTTTTGTCCGTGTCTTCACCGGCCAGGCCAAGGTCAAGGCCTCAGCCAGCAAGCAGGC GCTGGTGTTCCAGTGTGTGGGCTGCGGGGCCTTCCACCTTCAGCGTCTCGGCAAAGCGTCAGGAGTCCCCAGCGGCCGGGCCAAGTTCTC TGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGTGAACACTGTGGGCAACGACACCAGCTTGGTGGCCCCATGTGGGCAGAGCCCATCCA TGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCTGTGAGCGCTAACCCCGGCCGCTTCCACACCTCGGAGCGGATCCGAGGGGTCCTGAG CGTCATCACTGAGGAGCTCCCGGACGTGCCTCTGTACTACACCCTGGACCAGCTGAGCAGCACCATCCACTGCAACACACCAAGCCTCCT GCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTCCGGGTCTCACTCTCCCACGCCTGTAAGAACGCTGTGAAGACGGATGCCCCTGCCTC TGCCCTCTGGGACATCATGCGTTGCTGGGAGAAGGAATGTCCGGTGAAACGGGAGCGACTATCAGAGACTAGCCCAGCGTTCCGCATTCT CAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACCATCCGGGAAGATGCCAACCCCAGCTCCCGACAGCGAGGACTCAAGCGCTTCCAGGC TAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGTGCCCGGCCAGGGGGCAAGGCGGCCGACGAAGCTATGGAGGAGAGACGCAGGCTGCT TCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTGGCCCAGCGGGCTGCCCGGCTCAAGACATTTCCTTGCAAGAGGTTTAAGGAGGGCAC CTGTCAACGCGGGGACCAGTGCTGCTACTCCCACAGCCCCCCGACACCCAGGGTTTCTGCTGATGCTGCCCCTGACTGTCCAGAGACCTC >In-frame_RAB7A_ENST00000482525_chr3_128526514_+_TRMT1_ENST00000357720_chr19_13221120_-_1705nt ATAAAGCCTGAGGCGGCGGCAGCGGCGGAGTTGGCGGCTTGGAGAGCTCGGGAGAGTTCCCTGGAACCAGAACTTGGACCTTCTCGCTTC TGTCCTCCGTTTAGTCTCCTCCTCGGCGGGAGCCCTCGCGACGCGCCCGGCCCGGAGCCCCCAGCGCAGCGGCCGCGTTTGAAGGATGAC CTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAATAAGAA ATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAGATATG GGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTGGCCACAAAGCGGGC ACAGGCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAGGCCATCAACGTGGAGCAGGCGTTCCAGACGAT TGCACGGAATGCACTTAAGCAGGCCCTGAGAATCGTCCTGCACAGCCTGGACCTCCGCGCCAACTGCTACCAGCGCTTCGTGGTGCCGCT GCTCAGCATCAGCGCTGACTTCTACGTGCGTGTTTTTGTCCGTGTCTTCACCGGCCAGGCCAAGGTCAAGGCCTCAGCCAGCAAGCAGGC GCTGGTGTTCCAGTGTGTGGGCTGCGGGGCCTTCCACCTTCAGCGTCTCGGCAAAGCGTCAGGAGTCCCCAGCGGCCGGGCCAAGTTCTC TGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGTGAACACTGTGGGCAACGACACCAGCTTGGTGGCCCCATGTGGGCAGAGCCCATCCA TGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCTGTGAGCGCTAACCCCGGCCGCTTCCACACCTCGGAGCGGATCCGAGGGGTCCTGAG CGTCATCACTGAGGAGCTCCCGGACGTGCCTCTGTACTACACCCTGGACCAGCTGAGCAGCACCATCCACTGCAACACACCAAGCCTCCT GCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTCCGGGTCTCACTCTCCCACGCCTGTAAGAACGCTGTGAAGACGGATGCCCCTGCCTC TGCCCTCTGGGACATCATGCGTTGCTGGGAGAAGGAATGTCCGGTGAAACGGGAGCGACTATCAGAGACTAGCCCAGCGTTCCGCATTCT CAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACCATCCGGGAAGATGCCAACCCCAGCTCCCGACAGCGAGGACTCAAGCGCTTCCAGGC TAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGTGCCCGGCCAGGGGGCAAGGCGGCCGACGAAGCTATGGAGGAGAGACGCAGGCTGCT TCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTGGCCCAGCGGGCTGCCCGGCTCAAGACATTTCCTTGCAAGAGGTTTAAGGAGGGCAC CTGTCAACGCGGGGACCAGTGCTGCTACTCCCACAGCCCCCCGACACCCAGGGTTTCTGCTGATGCTGCCCCTGACTGTCCAGAGACCTC >In-frame_RAB7A_ENST00000482525_chr3_128526514_+_TRMT1_ENST00000221504_chr19_13221120_-_1613nt ATAAAGCCTGAGGCGGCGGCAGCGGCGGAGTTGGCGGCTTGGAGAGCTCGGGAGAGTTCCCTGGAACCAGAACTTGGACCTTCTCGCTTC TGTCCTCCGTTTAGTCTCCTCCTCGGCGGGAGCCCTCGCGACGCGCCCGGCCCGGAGCCCCCAGCGCAGCGGCCGCGTTTGAAGGATGAC CTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAATAAGAA ATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAGATATG GGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTGGCCACAAAGCGGGC ACAGGCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAGGCCATCAACGTGGAGCAGGCGTTCCAGACGAT TGCACGGAATGCACTTAAGCAGGCCCTGAGAATCGTCCTGCACAGCCTGGACCTCCGCGCCAACTGCTACCAGCGCTTCGTGGTGCCGCT GCTCAGCATCAGCGCTGACTTCTACGTGCGTGTTTTTGTCCGTGTCTTCACCGGCCAGGCCAAGGTCAAGGCCTCAGCCAGGGCCAAGTT CTCTGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGTGAACACTGTGGGCAACGACACCAGCTTGGTGGCCCCATGTGGGCAGAGCCCAT CCATGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCTGTGAGCGCTAACCCCGGCCGCTTCCACACCTCGGAGCGGATCCGAGGGGTCCT GAGCGTCATCACTGAGGAGCTCCCGGACGTGCCTCTGTACTACACCCTGGACCAGCTGAGCAGCACCATCCACTGCAACACACCAAGCCT CCTGCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTCCGGGTCTCACTCTCCCACGCCTGTAAGAACGCTGTGAAGACGGATGCCCCTGC CTCTGCCCTCTGGGACATCATGCGTTGCTGGGAGAAGGAATGTCCGGTGAAACGGGAGCGACTATCAGAGACTAGCCCAGCGTTCCGCAT TCTCAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACCATCCGGGAAGATGCCAACCCCAGCTCCCGACAGCGAGGACTCAAGCGCTTCCA GGCTAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGTGCCCGGCCAGGGGGCAAGGCGGCCGACGAAGCTATGGAGGAGAGACGCAGGCT GCTTCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTGGCCCAGCGGGCTGCCCGGCTCAAGACATTTCCTTGCAAGAGGTTTAAGGAGGG CACCTGTCAACGCGGGGACCAGTGCTGCTACTCCCACAGCCCCCCGACACCCAGGGTTTCTGCTGATGCTGCCCCTGACTGTCCAGAGAC >In-frame_RAB7A_ENST00000482525_chr3_128526514_+_TRMT1_ENST00000592062_chr19_13221120_-_1700nt ATAAAGCCTGAGGCGGCGGCAGCGGCGGAGTTGGCGGCTTGGAGAGCTCGGGAGAGTTCCCTGGAACCAGAACTTGGACCTTCTCGCTTC TGTCCTCCGTTTAGTCTCCTCCTCGGCGGGAGCCCTCGCGACGCGCCCGGCCCGGAGCCCCCAGCGCAGCGGCCGCGTTTGAAGGATGAC CTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAATAAGAA ATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAGATATG GGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTGGCCACAAAGCGGGC ACAGGCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAGGCCATCAACGTGGAGCAGGCGTTCCAGACGAT TGCACGGAATGCACTTAAGCAGGCCCTGAGAATCGTCCTGCACAGCCTGGACCTCCGCGCCAACTGCTACCAGCGCTTCGTGGTGCCGCT GCTCAGCATCAGCGCTGACTTCTACGTGCGTGTTTTTGTCCGTGTCTTCACCGGCCAGGCCAAGGTCAAGGCCTCAGCCAGCAAGCAGGC GCTGGTGTTCCAGTGTGTGGGCTGCGGGGCCTTCCACCTTCAGCGTCTCGGCAAAGCGTCAGGAGTCCCCAGCGGCCGGGCCAAGTTCTC TGCAGCCTGTGGTCCCCCTGTGACCCCCGAGTGTGAACACTGTGGGCAACGACACCAGCTTGGTGGCCCCATGTGGGCAGAGCCCATCCA TGACCTGGATTTTGTGGGCCGTGTCCTGGAGGCTGTGAGCGCTAACCCCGGCCGCTTCCACACCTCGGAGCGGATCCGAGGGGTCCTGAG CGTCATCACTGAGGAGCTCCCGGACGTGCCTCTGTACTACACCCTGGACCAGCTGAGCAGCACCATCCACTGCAACACACCAAGCCTCCT GCAGTTGCGGTCGGCCCTCCTCCACGCTGACTTCCGGGTCTCACTCTCCCACGCCTGTAAGAACGCTGTGAAGACGGATGCCCCTGCCTC TGCCCTCTGGGACATCATGCGTTGCTGGGAGAAGGAATGTCCGGTGAAACGGGAGCGACTATCAGAGACTAGCCCAGCGTTCCGCATTCT CAGTGTGGAGCCCAGGCTGCAGGCCAACTTCACCATCCGGGAAGATGCCAACCCCAGCTCCCGACAGCGAGGACTCAAGCGCTTCCAGGC TAACCCGGAGGCCAACTGGGGTCCCCGGCCTCGTGCCCGGCCAGGGGGCAAGGCGGCCGACGAAGCTATGGAGGAGAGACGCAGGCTGCT TCAGAACAAGCGGAAGGAGCCGCCGGAAGATGTGGCCCAGCGGGCTGCCCGGCTCAAGACATTTCCTTGCAAGAGGTTTAAGGAGGGCAC CTGTCAACGCGGGGACCAGTGCTGCTACTCCCACAGCCCCCCGACACCCAGGGTTTCTGCTGATGCTGCCCCTGACTGTCCAGAGACCTC |
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FusionGenePPI for RAB7A_TRMT1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RAB7A | EIF1B, CHM, RILP, RHEB, RAB17, RAB4A, RAB4B, RAB5A, RAB5B, RAB6A, RAB22A, PSMA7, UCHL5, PPP2R1A, PPP2R1B, ZFYVE28, ELAVL1, SLC2A4, KCNN4, RNF115, ATP13A2, RAB1A, RAB11A, RAB8A, RAB11B, EEF1A1, HNRNPK, EIF4G2, HSPA5, CORO1C, VCP, FN1, ATF2, BAG3, LGALS3, RPA1, RPA2, RPA3, FUS, KRTAP10-9, KRTAP10-3, CUL7, EED, UBAC2, FAF2, SNX3, VPS26A, VPS35, VPS29, VPS11, VPS16, VPS18, VPS39, VPS41, ANXA2, ARL8B, ATP5O, HSP90B1, HSPA9, MECR, RAB2A, RAB5C, APRT, DHRS7B, GDI2, HNRNPA3, MSI2, NUTF2, PDHA1, RAB10, RAB1B, RAP1A, RAP1B, SDHB, SLC25A3, UBE2V1, TMEM189-UBE2V1, RAB8B, TCTN2, TCTN3, CNTRL, FBF1, TMEM17, TMEM216, ABCD1, RHOG, ATP2A2, ATP2B1, ATP6V1B2, ATP6V0A1, ATP6AP1, CAV1, CFL1, AP2M1, CPM, CPT1A, STOM, FLOT2, GNB2, JUP, KTN1, NDUFA7, NDUFA8, NDUFB4, NDUFB7, NDUFB8, NDUFS1, NDUFS6, NDUFV2, PC, CHMP1A, PHB, ABCD3, RPN2, SOAT1, SSFA2, TFRC, VDAC1, VDAC2, GDI1, OAZ1, ATP6AP2, LAP3, GTSE1, GPRC5A, ATP6V0D1, XPR1, ABCG2, ATP6V1G1, MLEC, PIEZO1, IST1, LRPPRC, FLOT1, ERLIN1, CKAP4, IMMT, ERLIN2, PHB2, CHMP2B, MYOF, UQCRQ, CHMP2A, STOML2, TRPM7, CHCHD3, MUC13, KIDINS220, MBOAT7, TMEM43, CYBRD1, YIPF5, TMUB1, CHCHD6, CCDC115, MCU, PRKCDBP, CHMP4B, STT3B, PTRF, C6orf120, LRRK2, PARK2, NOTCH1, U2AF2, TSG101, CHMP5, COX15, DLST, TRIM25, TP53 | TRMT1 | MAGEA11, TERF1, ZNF598, ATP6V1B2, EPRS, TWF1, TXNDC5, TPRKB, KARS, ATP6V1B1, QARS, NUDC, IARS, DARS, VBP1, THUMPD2, C1QBP, JUP, CSDE1, GANAB, NARS, PDE3A, SAMHD1, XRCC5, AGO2, TARBP2, RFPL4B, SKAP1, LIPH, CTPS1, SEPT2, LARS, RTFDC1, CHCHD2, CHDH, HEMK1, WDYHV1, USP4, LIPG, PDP1, RSAD1, PDPR, D2HGDH, NDUFA12, CLPX, YBEY, DPP9, HDAC3, AKAP11, AARS2, NDUFS6, CCRN4L, SENP1, P4HA2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for RAB7A_TRMT1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for RAB7A_TRMT1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | RAB7A | C0151744 | Myocardial Ischemia | 1 | CTD_human |
| Hgene | RAB7A | C1833219 | CHARCOT-MARIE-TOOTH DISEASE, AXONAL, TYPE 2B (disorder) | 1 | CTD_human;ORPHANET;UNIPROT |
| Tgene | TRMT1 | C3714756 | Intellectual Disability | 1 | CTD_human |
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