FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 29874

FusionGeneSummary for RAB11B_HAUS3

check button Fusion gene summary
Fusion gene informationFusion gene name: RAB11B_HAUS3
Fusion gene ID: 29874
HgeneTgene
Gene symbol

RAB11B

HAUS3

Gene ID

9230

79441

Gene nameRAB11B, member RAS oncogene familyHAUS augmin like complex subunit 3
SynonymsH-YPT3|NDAGSCWC4orf15|IT1|dgt3
Cytomap

19p13.2

4p16.3

Type of geneprotein-codingprotein-coding
Descriptionras-related protein Rab-11BGTP-binding protein YPT3RAB11B, member of RAS oncogene familyHAUS augmin-like complex subunit 3
Modification date2018052320180523
UniProtAcc

Q15907

Q68CZ6

Ensembl transtripts involved in fusion geneENST00000328024, ENST00000601897, 
ENST00000594216, 
ENST00000506763, 
ENST00000243706, ENST00000443786, 
Fusion gene scores* DoF score7 X 6 X 3=1261 X 1 X 1=1
# samples 71
** MAII scorelog2(7/126*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(1/1*10)=3.32192809488736
Context

PubMed: RAB11B [Title/Abstract] AND HAUS3 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneRAB11B

GO:0071468

cellular response to acidic pH

20717956


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDOVTCGA-04-1348-01ARAB11Bchr19

8467449

+HAUS3chr4

2240770

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000328024ENST00000506763RAB11Bchr19

8467449

+HAUS3chr4

2240770

-
Frame-shiftENST00000328024ENST00000243706RAB11Bchr19

8467449

+HAUS3chr4

2240770

-
Frame-shiftENST00000328024ENST00000443786RAB11Bchr19

8467449

+HAUS3chr4

2240770

-
Frame-shiftENST00000601897ENST00000506763RAB11Bchr19

8467449

+HAUS3chr4

2240770

-
Frame-shiftENST00000601897ENST00000243706RAB11Bchr19

8467449

+HAUS3chr4

2240770

-
Frame-shiftENST00000601897ENST00000443786RAB11Bchr19

8467449

+HAUS3chr4

2240770

-
In-frameENST00000594216ENST00000506763RAB11Bchr19

8467449

+HAUS3chr4

2240770

-
In-frameENST00000594216ENST00000243706RAB11Bchr19

8467449

+HAUS3chr4

2240770

-
In-frameENST00000594216ENST00000443786RAB11Bchr19

8467449

+HAUS3chr4

2240770

-

Top

FusionProtFeatures for RAB11B_HAUS3


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
RAB11B

Q15907

HAUS3

Q68CZ6

Contributes to mitotic spindle assembly, maintenance ofcentrosome integrity and completion of cytokinesis as part of theHAUS augmin-like complex. {ECO:0000269|PubMed:19369198,ECO:0000269|PubMed:19427217}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for RAB11B_HAUS3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000506763_chr4_2240770_-_477aa
MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLV
YDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTGGRGPDGCGX
GTSQAGWNTASEPSLVLFVCLFFSFFCRGRMDFCSLPRLECGGSISAYCNLRLPGSGNSPASASRVAGITGACHHTRXFLXFLVETGFHN
VVQVDLELLGSSDPPASASQAVDKENLDAKISSLTSEIMKLEKEVTQIKDRSLPAVVRENAQLLNMPVVKGDFDLQIAKQDYYTARQELV
LNQLIKQKASFELLQLSYEIELRKHRDIYRQLENLVQELSQSNMMLYKQLEMLTDPSVSQQINPRNTIDTKDYSTHRLYQVLEGENKKKE

>In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000243706_chr4_2240770_-_591aa
MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLV
YDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTGGRGPDGCGX
GTSQAGWNTASEPSLVLFVCLFFSFFCRGRMDFCSLPRLECGGSISAYCNLRLPGSGNSPASASRVAGITGACHHTRXFLXFLVETGFHN
VVQVDLELLGSSDPPASASQAVDKENLDAKISSLTSEIMKLEKEVTQIKDRSLPAVVRENAQLLNMPVVKGDFDLQIAKQDYYTARQELV
LNQLIKQKASFELLQLSYEIELRKHRDIYRQLENLVQELSQSNMMLYKQLEMLTDPSVSQQINPRNTIDTKDYSTHRLYQVLEGENKKKE
LFLTHGNLEEVAEKLKQNISLVQDQLAVSAQEHSFFLSKRNKDVDMLCDTLYQGGNQLLLSDQELTEQFHKVESQLNKLNHLLTDILADV

>In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000443786_chr4_2240770_-_591aa
MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLV
YDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTGGRGPDGCGX
GTSQAGWNTASEPSLVLFVCLFFSFFCRGRMDFCSLPRLECGGSISAYCNLRLPGSGNSPASASRVAGITGACHHTRXFLXFLVETGFHN
VVQVDLELLGSSDPPASASQAVDKENLDAKISSLTSEIMKLEKEVTQIKDRSLPAVVRENAQLLNMPVVKGDFDLQIAKQDYYTARQELV
LNQLIKQKASFELLQLSYEIELRKHRDIYRQLENLVQELSQSNMMLYKQLEMLTDPSVSQQINPRNTIDTKDYSTHRLYQVLEGENKKKE
LFLTHGNLEEVAEKLKQNISLVQDQLAVSAQEHSFFLSKRNKDVDMLCDTLYQGGNQLLLSDQELTEQFHKVESQLNKLNHLLTDILADV


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000506763_chr4_2240770_-_1431nt
ATGGGGACCCGGGACGACGAGTACGACTACCTATTCAAAGTGGTGCTCATCGGGGACTCAGGCGTGGGCAAGAGCAACCTGCTGTCGCGC
TTCACCCGCAACGAGTTCAACCTGGAGAGCAAGAGCACCATCGGCGTGGAGTTCGCCACCCGCAGCATCCAGGTGGACGGCAAGACCATC
AAGGCGCAGATCTGGGACACCGCTGGCCAGGAGCGCTACCGCGCCATCACCTCCGCGTACTACCGTGGTGCAGTGGGCGCCCTGCTGGTG
TACGACATCGCCAAGCACCTGACCTATGAGAACGTGGAGCGCTGGCTGAAGGAGCTGCGGGACCACGCAGACAGCAACATCGTCATCATG
CTGGTGGGCAACAAGAGTGACCTGCGCCACCTGCGGGCTGTGCCCACTGACGAGGCCCGCGCCTTCGCAGAAAAGAACAACTTGTCCTTC
ATCGAGACCTCAGCCTTGGATTCCACTAACGTAGAGGAAGCATTCAAGAACATCCTCACAGGTGGCCGGGGACCAGATGGGTGTGGGTAG
GGCACCAGCCAGGCAGGGTGGAACACGGCCTCTGAACCTTCGCTTGTTTTGTTCGTTTGCTTGTTTTTTTCTTTTTTTTGTCGGGGCAGG
ATGGATTTTTGCTCTTTGCCCAGGCTGGAGTGTGGTGGCTCGATCTCAGCTTACTGCAACCTCCGCCTTCCAGGTTCAGGCAATTCTCCT
GCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCTGCCACCACACCCGCTAATTTTTGTAATTTTTAGTAGAGACAGGATTTCACAAT
GTTGTCCAGGTTGATCTCGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGCTGTGGACAAAGAAAATTTGGATGCTAAA
ATTTCTAGCTTGACCAGTGAGATTATGAAACTTGAAAAAGAGGTCACTCAAATAAAAGACAGAAGTTTACCTGCTGTGGTAAGAGAGAAT
GCCCAGTTATTGAATATGCCAGTGGTAAAGGGAGATTTTGATCTGCAGATTGCTAAACAAGATTATTATACAGCAAGACAAGAGTTAGTT
TTAAATCAATTAATAAAACAAAAGGCATCATTTGAACTTCTACAGTTATCATATGAAATTGAATTAAGAAAGCATCGGGACATATATCGT
CAACTTGAAAATTTGGTTCAAGAACTTAGTCAAAGTAACATGATGCTCTACAAGCAATTAGAAATGTTAACAGATCCATCAGTTTCTCAA
CAGATAAATCCAAGGAATACCATTGATACTAAGGATTATTCTACTCATAGGCTTTACCAAGTTTTGGAGGGAGAGAATAAGAAAAAAGAA

>In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000243706_chr4_2240770_-_1773nt
ATGGGGACCCGGGACGACGAGTACGACTACCTATTCAAAGTGGTGCTCATCGGGGACTCAGGCGTGGGCAAGAGCAACCTGCTGTCGCGC
TTCACCCGCAACGAGTTCAACCTGGAGAGCAAGAGCACCATCGGCGTGGAGTTCGCCACCCGCAGCATCCAGGTGGACGGCAAGACCATC
AAGGCGCAGATCTGGGACACCGCTGGCCAGGAGCGCTACCGCGCCATCACCTCCGCGTACTACCGTGGTGCAGTGGGCGCCCTGCTGGTG
TACGACATCGCCAAGCACCTGACCTATGAGAACGTGGAGCGCTGGCTGAAGGAGCTGCGGGACCACGCAGACAGCAACATCGTCATCATG
CTGGTGGGCAACAAGAGTGACCTGCGCCACCTGCGGGCTGTGCCCACTGACGAGGCCCGCGCCTTCGCAGAAAAGAACAACTTGTCCTTC
ATCGAGACCTCAGCCTTGGATTCCACTAACGTAGAGGAAGCATTCAAGAACATCCTCACAGGTGGCCGGGGACCAGATGGGTGTGGGTAG
GGCACCAGCCAGGCAGGGTGGAACACGGCCTCTGAACCTTCGCTTGTTTTGTTCGTTTGCTTGTTTTTTTCTTTTTTTTGTCGGGGCAGG
ATGGATTTTTGCTCTTTGCCCAGGCTGGAGTGTGGTGGCTCGATCTCAGCTTACTGCAACCTCCGCCTTCCAGGTTCAGGCAATTCTCCT
GCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCTGCCACCACACCCGCTAATTTTTGTAATTTTTAGTAGAGACAGGATTTCACAAT
GTTGTCCAGGTTGATCTCGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGCTGTGGACAAAGAAAATTTGGATGCTAAA
ATTTCTAGCTTGACCAGTGAGATTATGAAACTTGAAAAAGAGGTCACTCAAATAAAAGACAGAAGTTTACCTGCTGTGGTAAGAGAGAAT
GCCCAGTTATTGAATATGCCAGTGGTAAAGGGAGATTTTGATCTGCAGATTGCTAAACAAGATTATTATACAGCAAGACAAGAGTTAGTT
TTAAATCAATTAATAAAACAAAAGGCATCATTTGAACTTCTACAGTTATCATATGAAATTGAATTAAGAAAGCATCGGGACATATATCGT
CAACTTGAAAATTTGGTTCAAGAACTTAGTCAAAGTAACATGATGCTCTACAAGCAATTAGAAATGTTAACAGATCCATCAGTTTCTCAA
CAGATAAATCCAAGGAATACCATTGATACTAAGGATTATTCTACTCATAGGCTTTACCAAGTTTTGGAGGGAGAGAATAAGAAAAAAGAA
TTGTTTCTAACTCATGGAAACCTTGAGGAAGTGGCTGAGAAATTGAAACAGAATATTTCTTTAGTACAAGATCAGTTGGCAGTATCTGCT
CAAGAACATTCTTTCTTTCTGTCCAAACGGAATAAGGATGTGGACATGCTTTGTGATACTTTGTATCAAGGAGGAAATCAGCTTTTGCTT
AGTGATCAGGAGTTAACAGAGCAGTTTCATAAAGTTGAATCTCAACTGAATAAGCTAAATCATCTCCTCACTGATATTCTTGCTGATGTG
AAGACAAAAAGAAAAACTTTGGCAAATAATAAATTACATCAAATGGAAAGAGAATTCTATGTATATTTTTTAAAAGATGAAGATTATCTG

>In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000443786_chr4_2240770_-_1773nt
ATGGGGACCCGGGACGACGAGTACGACTACCTATTCAAAGTGGTGCTCATCGGGGACTCAGGCGTGGGCAAGAGCAACCTGCTGTCGCGC
TTCACCCGCAACGAGTTCAACCTGGAGAGCAAGAGCACCATCGGCGTGGAGTTCGCCACCCGCAGCATCCAGGTGGACGGCAAGACCATC
AAGGCGCAGATCTGGGACACCGCTGGCCAGGAGCGCTACCGCGCCATCACCTCCGCGTACTACCGTGGTGCAGTGGGCGCCCTGCTGGTG
TACGACATCGCCAAGCACCTGACCTATGAGAACGTGGAGCGCTGGCTGAAGGAGCTGCGGGACCACGCAGACAGCAACATCGTCATCATG
CTGGTGGGCAACAAGAGTGACCTGCGCCACCTGCGGGCTGTGCCCACTGACGAGGCCCGCGCCTTCGCAGAAAAGAACAACTTGTCCTTC
ATCGAGACCTCAGCCTTGGATTCCACTAACGTAGAGGAAGCATTCAAGAACATCCTCACAGGTGGCCGGGGACCAGATGGGTGTGGGTAG
GGCACCAGCCAGGCAGGGTGGAACACGGCCTCTGAACCTTCGCTTGTTTTGTTCGTTTGCTTGTTTTTTTCTTTTTTTTGTCGGGGCAGG
ATGGATTTTTGCTCTTTGCCCAGGCTGGAGTGTGGTGGCTCGATCTCAGCTTACTGCAACCTCCGCCTTCCAGGTTCAGGCAATTCTCCT
GCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCTGCCACCACACCCGCTAATTTTTGTAATTTTTAGTAGAGACAGGATTTCACAAT
GTTGTCCAGGTTGATCTCGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGCTGTGGACAAAGAAAATTTGGATGCTAAA
ATTTCTAGCTTGACCAGTGAGATTATGAAACTTGAAAAAGAGGTCACTCAAATAAAAGACAGAAGTTTACCTGCTGTGGTAAGAGAGAAT
GCCCAGTTATTGAATATGCCAGTGGTAAAGGGAGATTTTGATCTGCAGATTGCTAAACAAGATTATTATACAGCAAGACAAGAGTTAGTT
TTAAATCAATTAATAAAACAAAAGGCATCATTTGAACTTCTACAGTTATCATATGAAATTGAATTAAGAAAGCATCGGGACATATATCGT
CAACTTGAAAATTTGGTTCAAGAACTTAGTCAAAGTAACATGATGCTCTACAAGCAATTAGAAATGTTAACAGATCCATCAGTTTCTCAA
CAGATAAATCCAAGGAATACCATTGATACTAAGGATTATTCTACTCATAGGCTTTACCAAGTTTTGGAGGGAGAGAATAAGAAAAAAGAA
TTGTTTCTAACTCATGGAAACCTTGAGGAAGTGGCTGAGAAATTGAAACAGAATATTTCTTTAGTACAAGATCAGTTGGCAGTATCTGCT
CAAGAACATTCTTTCTTTCTGTCCAAACGGAATAAGGATGTGGACATGCTTTGTGATACTTTGTATCAAGGAGGAAATCAGCTTTTGCTT
AGTGATCAGGAGTTAACAGAGCAGTTTCATAAAGTTGAATCTCAACTGAATAAGCTAAATCATCTCCTCACTGATATTCTTGCTGATGTG
AAGACAAAAAGAAAAACTTTGGCAAATAATAAATTACATCAAATGGAAAGAGAATTCTATGTATATTTTTTAAAAGATGAAGATTATCTG


* Fusion transcript sequences (Full-length transcript).
>In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000506763_chr4_2240770_-_2476nt
GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA
AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGTGCTCATCGGGGACTCAGGCGTGGGCAAGAGCAACCTGC
TGTCGCGCTTCACCCGCAACGAGTTCAACCTGGAGAGCAAGAGCACCATCGGCGTGGAGTTCGCCACCCGCAGCATCCAGGTGGACGGCA
AGACCATCAAGGCGCAGATCTGGGACACCGCTGGCCAGGAGCGCTACCGCGCCATCACCTCCGCGTACTACCGTGGTGCAGTGGGCGCCC
TGCTGGTGTACGACATCGCCAAGCACCTGACCTATGAGAACGTGGAGCGCTGGCTGAAGGAGCTGCGGGACCACGCAGACAGCAACATCG
TCATCATGCTGGTGGGCAACAAGAGTGACCTGCGCCACCTGCGGGCTGTGCCCACTGACGAGGCCCGCGCCTTCGCAGAAAAGAACAACT
TGTCCTTCATCGAGACCTCAGCCTTGGATTCCACTAACGTAGAGGAAGCATTCAAGAACATCCTCACAGGTGGCCGGGGACCAGATGGGT
GTGGGTAGGGCACCAGCCAGGCAGGGTGGAACACGGCCTCTGAACCTTCGCTTGTTTTGTTCGTTTGCTTGTTTTTTTCTTTTTTTTGTC
GGGGCAGGATGGATTTTTGCTCTTTGCCCAGGCTGGAGTGTGGTGGCTCGATCTCAGCTTACTGCAACCTCCGCCTTCCAGGTTCAGGCA
ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCTGCCACCACACCCGCTAATTTTTGTAATTTTTAGTAGAGACAGGAT
TTCACAATGTTGTCCAGGTTGATCTCGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGCTGTGGACAAAGAAAATTTGG
ATGCTAAAATTTCTAGCTTGACCAGTGAGATTATGAAACTTGAAAAAGAGGTCACTCAAATAAAAGACAGAAGTTTACCTGCTGTGGTAA
GAGAGAATGCCCAGTTATTGAATATGCCAGTGGTAAAGGGAGATTTTGATCTGCAGATTGCTAAACAAGATTATTATACAGCAAGACAAG
AGTTAGTTTTAAATCAATTAATAAAACAAAAGGCATCATTTGAACTTCTACAGTTATCATATGAAATTGAATTAAGAAAGCATCGGGACA
TATATCGTCAACTTGAAAATTTGGTTCAAGAACTTAGTCAAAGTAACATGATGCTCTACAAGCAATTAGAAATGTTAACAGATCCATCAG
TTTCTCAACAGATAAATCCAAGGAATACCATTGATACTAAGGATTATTCTACTCATAGGCTTTACCAAGTTTTGGAGGGAGAGAATAAGA
AAAAAGAATTGTTTCTAACTCATGGAAACCTTGAGGAAGTGGCTGAGGCAGGAGAATGGCATGAACCCAGGAGGCGGGGCTTGCAGTGAG
CTGAGGTCTCCAGCGTGGGCGACAGAGTGAGACTCTATCTCAAAAAAAAAAAAAAAAAAAAGTGAAAGCAGTGATATGCTCACAAATGTC
ACTGAAATGTTTATAACATCAGGGCTTTTGGTGTTTTTTTGTTTTGTTTTTTGTTGGTGTTTTTTTTTTTTTTTTGCTACTAGCAAAGCA
GTTTTTATTTTAAATTTGCAAGCCTGGGCCAATAGTTTGTGGTTGGTTTCTCTTTCTACAAAATAAGGTATAAGTGAGTGAGATATAATT
GAGTAATGAAATTGCATTGAAATAATTGAGAGTATTGCCGAATATTAGCACAAAAGCTCTTATAAACACATCTTGATTAAGATACATTTG
CACTTAACGTTTTGATCCATTCATATTGAGGCATCTGTTGCTTATATACTTTATTATAGTAGAAGTCACTAATAAACTGGTAAGAATTTT
TGAGTGTGAATTACATGCCTAGCAATTGATAGTGTAAGACACTATCATAATCACATTATTCCATATTTTTTTGAATAATAGAGGGTGCAT
ACTTGACAGAGGTGGAAATATACTCCCCTTCAAAAACCGGTAAGAATAATGAAATGCCTCTGGCAGCTATAATATGAGGCTCTGATGAAA
AATTTACGACAGTCAGTCCATCTCATATAAGCTCTTATTGTTGTTCTAAAATACATTGTTAATGCCTGGGACGATCACTTGAGCCCAGGA
GTTCGAGTCCAGCCTAGGCAACATAGCAAGATCTCATCTCTGAAAATAAAATACCCCGTTAAAATTCTGGCTTTTGTTTGTTAAGGTTAT
TGAGAAGGTAATAGAAAAAGATATGATACTACTTTTCTCTCTTGGATTTGTAAAAATAGTGGAATTTTCATAAGGATTTTGTATTTTCTA

>In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000243706_chr4_2240770_-_5449nt
GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA
AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGTGCTCATCGGGGACTCAGGCGTGGGCAAGAGCAACCTGC
TGTCGCGCTTCACCCGCAACGAGTTCAACCTGGAGAGCAAGAGCACCATCGGCGTGGAGTTCGCCACCCGCAGCATCCAGGTGGACGGCA
AGACCATCAAGGCGCAGATCTGGGACACCGCTGGCCAGGAGCGCTACCGCGCCATCACCTCCGCGTACTACCGTGGTGCAGTGGGCGCCC
TGCTGGTGTACGACATCGCCAAGCACCTGACCTATGAGAACGTGGAGCGCTGGCTGAAGGAGCTGCGGGACCACGCAGACAGCAACATCG
TCATCATGCTGGTGGGCAACAAGAGTGACCTGCGCCACCTGCGGGCTGTGCCCACTGACGAGGCCCGCGCCTTCGCAGAAAAGAACAACT
TGTCCTTCATCGAGACCTCAGCCTTGGATTCCACTAACGTAGAGGAAGCATTCAAGAACATCCTCACAGGTGGCCGGGGACCAGATGGGT
GTGGGTAGGGCACCAGCCAGGCAGGGTGGAACACGGCCTCTGAACCTTCGCTTGTTTTGTTCGTTTGCTTGTTTTTTTCTTTTTTTTGTC
GGGGCAGGATGGATTTTTGCTCTTTGCCCAGGCTGGAGTGTGGTGGCTCGATCTCAGCTTACTGCAACCTCCGCCTTCCAGGTTCAGGCA
ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCTGCCACCACACCCGCTAATTTTTGTAATTTTTAGTAGAGACAGGAT
TTCACAATGTTGTCCAGGTTGATCTCGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGCTGTGGACAAAGAAAATTTGG
ATGCTAAAATTTCTAGCTTGACCAGTGAGATTATGAAACTTGAAAAAGAGGTCACTCAAATAAAAGACAGAAGTTTACCTGCTGTGGTAA
GAGAGAATGCCCAGTTATTGAATATGCCAGTGGTAAAGGGAGATTTTGATCTGCAGATTGCTAAACAAGATTATTATACAGCAAGACAAG
AGTTAGTTTTAAATCAATTAATAAAACAAAAGGCATCATTTGAACTTCTACAGTTATCATATGAAATTGAATTAAGAAAGCATCGGGACA
TATATCGTCAACTTGAAAATTTGGTTCAAGAACTTAGTCAAAGTAACATGATGCTCTACAAGCAATTAGAAATGTTAACAGATCCATCAG
TTTCTCAACAGATAAATCCAAGGAATACCATTGATACTAAGGATTATTCTACTCATAGGCTTTACCAAGTTTTGGAGGGAGAGAATAAGA
AAAAAGAATTGTTTCTAACTCATGGAAACCTTGAGGAAGTGGCTGAGAAATTGAAACAGAATATTTCTTTAGTACAAGATCAGTTGGCAG
TATCTGCTCAAGAACATTCTTTCTTTCTGTCCAAACGGAATAAGGATGTGGACATGCTTTGTGATACTTTGTATCAAGGAGGAAATCAGC
TTTTGCTTAGTGATCAGGAGTTAACAGAGCAGTTTCATAAAGTTGAATCTCAACTGAATAAGCTAAATCATCTCCTCACTGATATTCTTG
CTGATGTGAAGACAAAAAGAAAAACTTTGGCAAATAATAAATTACATCAAATGGAAAGAGAATTCTATGTATATTTTTTAAAAGATGAAG
ATTATCTGAAAGATATTGTGGAGAATTTAGAAACTCAATCAAAGATTAAGGCTGTTAGTCTTGAAGATTGAAAATTACTGAAAACTGAAT
CTTTATTACGTGTCCTCTTTTATTTATTAGAAGACTGTGTATAATAAACACTACTAAATTTTTAAAATTTGAGGTCAATGGAACATTTAA
TTTGATGAATTGAACTATTATATTAATTTGTCTTTTTTCTCATGTAGTACATTCAGAATACCAGTGCTTTTTATGACTTGAGCATGTGTT
TAGTGGTACTTAGTCCTGGTAATTTTTTACTTACAGGGAAAAAGCATTATTACATAATGCAAATATTTTTTAATATAGTTATCTCTCTCC
TTTTTAGAAATAGAAATTTTCTGCCGTTAAATTTTTTTTTGAGATAGAGTCTCACTCTGTCTCCAGGCTGGAATGCAGTGGCACGATCTT
GGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCGCACACCGCCACAC
CCAGCTAATTTTTTTGTATTTTAGTAGAAAAGGGGTTTCACCATGTTGGCCAGGATGGTCTCAATCTCTTGACCTCTTGATCCCCTCTCC
CGGCCTCCCAAAGTGCCGGAATTACAGGCATGAGCCACCACGCTCAGCCGCTATTAAATATTTTAAAATGTGTAGAACTTCTAGTCAGCA
TTTTTAAATCTGTAGACCTTAATATGTGAAATAGCCAAGTCCCCTCATGTTTGACTGTCAAATAAAATTCTGCTGCTCAAATTGTATTCC
TCCATAATTCCCTGCTATAGACCTTTAGGCTGTTTTAATGTCCCTACTTGTACCACAGAGTATTAGGACTTCCTTGGCCTGCCTGCATTC
ATTTTAGAGTCTGAATTCTGGGGACTCAAAAGTTTCTACAAGACAGCTGAGCAGTGCTTTGACTTTAATGTGACTTACACATCATAAATG
ACTTTCAAATGAAATTTGAATTTCAAAATTCTGTAAAAGTGGTTGCTCAAAAGATGTATGATACTATTTTAATCAGTTTAAGAGCAAAAA
TGTCTAATTGTATTTAACAATGGTATTTGGGCAGCCAGAAAATATTTTAAGCGTTGCTCTAAAATAATTTGAAGTAGCTCATCTGTTATT
ACATCAGATGCTTCTTGAGTGCCCAATTTATACATGGCCTGTGGTAAATACCATGTGAGCTTTGTAGGAATACCTTTAAGAATATTCCTC
ACCTGTTCGTAATATGGAATGCCAATCTAAAAACTACATGTTTTGGGTGGTCTTTATGGAATTTTTTAGCTATAACCATCAGAAAACAGG
CATACCTAGATGACAGATGAACCTTCTTGATTTTTGAAACCCATTGAACAAAAATATTTTGCCAATTATTGTGTTTATGTTATTTAAAAT
TTTATGTAAACCTTAATTTTGTAGCAGTAAATTTTGTTTAAGATTTTGCTATCAGCTCCCTATCACCTGAGCAACTTTTTTTTTGTTGTA
TATGTTTTTTTCTATTCTATTTCGGAATAGAGAATTTACTTAAAATTTTTATTTTCTCCAAAAATGTGGAAAATATGTCACCTGGTTTCC
TGGTTTATGGTAGCATATTCTGTTTAAATTAGTGTCACATATTTAGATGTGTGGCCAGACGCTTGATTTATTAGTTAATTTTTGAGACAG
AGTCTAACTGTGTCACTCAGGCTGGAGTTCAGTGGAATGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATTCTCCTGCT
TCAGCCTCCTGAGTAGATGGGATTGTAGGCGTGCACCACTGCACCTGGCTAATTTTTGTATTTTCAGTAGAGACGGGGTTTCACCATGTT
GGTCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCTACCCGCCTTGGCCTTCCATAGTGCTGGCATTACAGGTGTAAGCCACCATGCC
CCTGCCCAGATGCTTGATTTATACTGTCCCCACCCAAACCTTGACTTGCTCAGCCCAGGGGGCCAGCAGGGCAGATCAAGGCACGGATGG
TAGTTGTGTGTCTGCCGTAATTACCCAAGTTACTTATAATCGTTGTGTTACTAGGTAGGTTTATTTGAAGATTTATTTATTTATTTATTT
ATTTTTTATTTTTTGAGACGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTCAGCTCACTGCAACCTCTGCCTTCT
GGGTTCACGTGATTCTCCTGCCTCAGGCCTCCCGAGTAGCTGGGATTACAGGTGCCACCATGCCTGGTTAATTTTTTGTATTTTTAGTAG
AGACGGGGTTTCATCATGTTGGCCAGGTTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCGCCTCAGTCTACCAAAGTGCAGGGATCA
CAGGCATGAGCTTCCGCGCTCAGCCTATTTGAAGATTTAATAACATTTTTCAAACCTCAGGATGTATTTGAGTAGATTGCTTCTAAATTG
GTCACCTAGAAAATAAGTTATCTATTTACTATGATACCTGGATTAAGCCTCTAGCTATTTTGCTTTTTTCTTTCTATCTATATTATTGGA
TGATTGATGCCTATTTTCTGTGGTTATGAATATAGACATTTTAAATGAAAGTTGGTATATAAATTTTTGAAAATAATTGTATTTCCTGTT
TTATAGTCTTAGGATTAATATATGGGATTTATCTTATGTTAATCTTACATTTAGGATTTTGTGAAAATGGAAAATTATGAGGCATTGGTA
GGCTTTGATCTCTGTAATACACCGCTCTCCAGTGTTGCTCAGAAGATTATGTCTGCTATGCATTCAGGTGATTTAGTGGATTCTAAGACT
TGGGGAAAGAGTACAGAGAGTAAGTAATTTTTATGAACCTTTCTTTCTCTTGATACTTTGAATGTTAATTGTTCTAAAGACTAAGAATTG
AAAATGGAATGCATGTAGACAGATGAAGCCCAGCTCCCGCCCCTTTTACACTCATTCAGTGCAGACTGAGCTTCTGCTTGCTAACTTTCG
TGTTCCCTTAACCTTCATTGCTTTAAAAATGTAACACTCTCTTCCTTATTCCAGGTATTTCTGTCAAACATTCCCTTAGAATCTGGATCA
GGTATTTTAGTATTTTCAAAAGAGATGCTTTAATCTTGGTTCTCAGGTCATCAAACCTGTACATAGTATTTGCTATTTTGTGTGGTGAAC
AAGAGATATGTTTTTGACAATATGTGTATTGTGCTGCTATAGAAATGTAAACTCTTAGGTGGCAAGGATTATTGGATCAGTGTATATGGA
TTTATGATGTGGTATAATAGTAAAAGCAGTGGGGCCGGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTCGGCG
ATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTAAAACACTGTCTCTACTAAAAATACAAAAAATTAGCTGGGAGTGGTGG
TAGGCGCCTGTAGTCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCATGAACCCAGGAGGCGGGGCTTGCAGTGAGCTGAGGTCTCCA

>In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000443786_chr4_2240770_-_1957nt
GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA
AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGTGCTCATCGGGGACTCAGGCGTGGGCAAGAGCAACCTGC
TGTCGCGCTTCACCCGCAACGAGTTCAACCTGGAGAGCAAGAGCACCATCGGCGTGGAGTTCGCCACCCGCAGCATCCAGGTGGACGGCA
AGACCATCAAGGCGCAGATCTGGGACACCGCTGGCCAGGAGCGCTACCGCGCCATCACCTCCGCGTACTACCGTGGTGCAGTGGGCGCCC
TGCTGGTGTACGACATCGCCAAGCACCTGACCTATGAGAACGTGGAGCGCTGGCTGAAGGAGCTGCGGGACCACGCAGACAGCAACATCG
TCATCATGCTGGTGGGCAACAAGAGTGACCTGCGCCACCTGCGGGCTGTGCCCACTGACGAGGCCCGCGCCTTCGCAGAAAAGAACAACT
TGTCCTTCATCGAGACCTCAGCCTTGGATTCCACTAACGTAGAGGAAGCATTCAAGAACATCCTCACAGGTGGCCGGGGACCAGATGGGT
GTGGGTAGGGCACCAGCCAGGCAGGGTGGAACACGGCCTCTGAACCTTCGCTTGTTTTGTTCGTTTGCTTGTTTTTTTCTTTTTTTTGTC
GGGGCAGGATGGATTTTTGCTCTTTGCCCAGGCTGGAGTGTGGTGGCTCGATCTCAGCTTACTGCAACCTCCGCCTTCCAGGTTCAGGCA
ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCTGCCACCACACCCGCTAATTTTTGTAATTTTTAGTAGAGACAGGAT
TTCACAATGTTGTCCAGGTTGATCTCGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGCTGTGGACAAAGAAAATTTGG
ATGCTAAAATTTCTAGCTTGACCAGTGAGATTATGAAACTTGAAAAAGAGGTCACTCAAATAAAAGACAGAAGTTTACCTGCTGTGGTAA
GAGAGAATGCCCAGTTATTGAATATGCCAGTGGTAAAGGGAGATTTTGATCTGCAGATTGCTAAACAAGATTATTATACAGCAAGACAAG
AGTTAGTTTTAAATCAATTAATAAAACAAAAGGCATCATTTGAACTTCTACAGTTATCATATGAAATTGAATTAAGAAAGCATCGGGACA
TATATCGTCAACTTGAAAATTTGGTTCAAGAACTTAGTCAAAGTAACATGATGCTCTACAAGCAATTAGAAATGTTAACAGATCCATCAG
TTTCTCAACAGATAAATCCAAGGAATACCATTGATACTAAGGATTATTCTACTCATAGGCTTTACCAAGTTTTGGAGGGAGAGAATAAGA
AAAAAGAATTGTTTCTAACTCATGGAAACCTTGAGGAAGTGGCTGAGAAATTGAAACAGAATATTTCTTTAGTACAAGATCAGTTGGCAG
TATCTGCTCAAGAACATTCTTTCTTTCTGTCCAAACGGAATAAGGATGTGGACATGCTTTGTGATACTTTGTATCAAGGAGGAAATCAGC
TTTTGCTTAGTGATCAGGAGTTAACAGAGCAGTTTCATAAAGTTGAATCTCAACTGAATAAGCTAAATCATCTCCTCACTGATATTCTTG
CTGATGTGAAGACAAAAAGAAAAACTTTGGCAAATAATAAATTACATCAAATGGAAAGAGAATTCTATGTATATTTTTTAAAAGATGAAG
ATTATCTGAAAGATATTGTGGAGAATTTAGAAACTCAATCAAAGATTAAGGCTGTTAGTCTTGAAGATTGAAAATTACTGAAAACTGAAT


Top

FusionGenePPI for RAB11B_HAUS3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
RAB11BRAB11FIP1, RAB11FIP2, RAB11FIP3, RAB11FIP5, H2AFX, CDK2, APP, GDI1, RAB1A, GDI2, RAB11A, RAB1B, RAB8A, RAB7A, ATP6V1H, HNRNPUL1, DDX28, ABCC2, HNRNPUL2, VCP, ATP4A, MYO5B, RPA3, RPA2, RPA1, OPTN, CUL7, WDR44, CHML, CHM, SH3BP5L, RAB25, SH3BP5, S100A3, SERPINB5, SELENBP1, LYG2, LRRC15, DNPEP, HEPHL1, LGALS3, VSIG8, DSG4, CALML3, DUSP14, PLCD1, PADI3, HIST1H2AG, FAM26D, TRIM27, PROCR, ETNK2, FAM217B, DUT, GNAI3, NUTF2, PHB2, ARF1, CDC42, PGAM1, RAB5A, RAB6A, UAP1L1, RAB5B, RAB5C, OFD1, CNTRL, SCLT1, TMEM17, IKBKG, GOLT1B, LRRK2, CDH1, RBM42, BSPRY, IFIT2, SCEL, NT5C3AHAUS3HAUS6, KDM1A, HAUS2, C19orf57, TXLNB, TXLNA, HAUS7, COG3, MED4, SSX2IP, OFD1, PCM1, CEP170, KIAA0753, CEP104, CEP162, CEP290, CEP120, CEP152, SPICE1, CEP128, CEP135, CEP44, CEP63, CEP89, CNTRL, FBF1, NIN, ODF2, RPGRIP1L, POC5, LCA5, SASS6, CENPJ, XPO1, SMC1A, SYCE3, CDC16, C6orf141, CRYL1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for RAB11B_HAUS3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for RAB11B_HAUS3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneRAB11BC0019693HIV Infections1CTD_human