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Fusion gene ID: 29874 |
FusionGeneSummary for RAB11B_HAUS3 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: RAB11B_HAUS3 | Fusion gene ID: 29874 | Hgene | Tgene | Gene symbol | RAB11B | HAUS3 | Gene ID | 9230 | 79441 |
| Gene name | RAB11B, member RAS oncogene family | HAUS augmin like complex subunit 3 | |
| Synonyms | H-YPT3|NDAGSCW | C4orf15|IT1|dgt3 | |
| Cytomap | 19p13.2 | 4p16.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ras-related protein Rab-11BGTP-binding protein YPT3RAB11B, member of RAS oncogene family | HAUS augmin-like complex subunit 3 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | Q15907 | Q68CZ6 | |
| Ensembl transtripts involved in fusion gene | ENST00000328024, ENST00000601897, ENST00000594216, | ENST00000506763, ENST00000243706, ENST00000443786, | |
| Fusion gene scores | * DoF score | 7 X 6 X 3=126 | 1 X 1 X 1=1 |
| # samples | 7 | 1 | |
| ** MAII score | log2(7/126*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(1/1*10)=3.32192809488736 | |
| Context | PubMed: RAB11B [Title/Abstract] AND HAUS3 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | RAB11B | GO:0071468 | cellular response to acidic pH | 20717956 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | OV | TCGA-04-1348-01A | RAB11B | chr19 | 8467449 | + | HAUS3 | chr4 | 2240770 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000328024 | ENST00000506763 | RAB11B | chr19 | 8467449 | + | HAUS3 | chr4 | 2240770 | - |
| Frame-shift | ENST00000328024 | ENST00000243706 | RAB11B | chr19 | 8467449 | + | HAUS3 | chr4 | 2240770 | - |
| Frame-shift | ENST00000328024 | ENST00000443786 | RAB11B | chr19 | 8467449 | + | HAUS3 | chr4 | 2240770 | - |
| Frame-shift | ENST00000601897 | ENST00000506763 | RAB11B | chr19 | 8467449 | + | HAUS3 | chr4 | 2240770 | - |
| Frame-shift | ENST00000601897 | ENST00000243706 | RAB11B | chr19 | 8467449 | + | HAUS3 | chr4 | 2240770 | - |
| Frame-shift | ENST00000601897 | ENST00000443786 | RAB11B | chr19 | 8467449 | + | HAUS3 | chr4 | 2240770 | - |
| In-frame | ENST00000594216 | ENST00000506763 | RAB11B | chr19 | 8467449 | + | HAUS3 | chr4 | 2240770 | - |
| In-frame | ENST00000594216 | ENST00000243706 | RAB11B | chr19 | 8467449 | + | HAUS3 | chr4 | 2240770 | - |
| In-frame | ENST00000594216 | ENST00000443786 | RAB11B | chr19 | 8467449 | + | HAUS3 | chr4 | 2240770 | - |
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FusionProtFeatures for RAB11B_HAUS3 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| RAB11B | HAUS3 |
| Contributes to mitotic spindle assembly, maintenance ofcentrosome integrity and completion of cytokinesis as part of theHAUS augmin-like complex. {ECO:0000269|PubMed:19369198,ECO:0000269|PubMed:19427217}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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FusionGeneSequence for RAB11B_HAUS3 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000506763_chr4_2240770_-_477aa MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLV YDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTGGRGPDGCGX GTSQAGWNTASEPSLVLFVCLFFSFFCRGRMDFCSLPRLECGGSISAYCNLRLPGSGNSPASASRVAGITGACHHTRXFLXFLVETGFHN VVQVDLELLGSSDPPASASQAVDKENLDAKISSLTSEIMKLEKEVTQIKDRSLPAVVRENAQLLNMPVVKGDFDLQIAKQDYYTARQELV LNQLIKQKASFELLQLSYEIELRKHRDIYRQLENLVQELSQSNMMLYKQLEMLTDPSVSQQINPRNTIDTKDYSTHRLYQVLEGENKKKE >In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000243706_chr4_2240770_-_591aa MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLV YDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTGGRGPDGCGX GTSQAGWNTASEPSLVLFVCLFFSFFCRGRMDFCSLPRLECGGSISAYCNLRLPGSGNSPASASRVAGITGACHHTRXFLXFLVETGFHN VVQVDLELLGSSDPPASASQAVDKENLDAKISSLTSEIMKLEKEVTQIKDRSLPAVVRENAQLLNMPVVKGDFDLQIAKQDYYTARQELV LNQLIKQKASFELLQLSYEIELRKHRDIYRQLENLVQELSQSNMMLYKQLEMLTDPSVSQQINPRNTIDTKDYSTHRLYQVLEGENKKKE LFLTHGNLEEVAEKLKQNISLVQDQLAVSAQEHSFFLSKRNKDVDMLCDTLYQGGNQLLLSDQELTEQFHKVESQLNKLNHLLTDILADV >In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000443786_chr4_2240770_-_591aa MGTRDDEYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQERYRAITSAYYRGAVGALLV YDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTGGRGPDGCGX GTSQAGWNTASEPSLVLFVCLFFSFFCRGRMDFCSLPRLECGGSISAYCNLRLPGSGNSPASASRVAGITGACHHTRXFLXFLVETGFHN VVQVDLELLGSSDPPASASQAVDKENLDAKISSLTSEIMKLEKEVTQIKDRSLPAVVRENAQLLNMPVVKGDFDLQIAKQDYYTARQELV LNQLIKQKASFELLQLSYEIELRKHRDIYRQLENLVQELSQSNMMLYKQLEMLTDPSVSQQINPRNTIDTKDYSTHRLYQVLEGENKKKE LFLTHGNLEEVAEKLKQNISLVQDQLAVSAQEHSFFLSKRNKDVDMLCDTLYQGGNQLLLSDQELTEQFHKVESQLNKLNHLLTDILADV |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000506763_chr4_2240770_-_1431nt ATGGGGACCCGGGACGACGAGTACGACTACCTATTCAAAGTGGTGCTCATCGGGGACTCAGGCGTGGGCAAGAGCAACCTGCTGTCGCGC TTCACCCGCAACGAGTTCAACCTGGAGAGCAAGAGCACCATCGGCGTGGAGTTCGCCACCCGCAGCATCCAGGTGGACGGCAAGACCATC AAGGCGCAGATCTGGGACACCGCTGGCCAGGAGCGCTACCGCGCCATCACCTCCGCGTACTACCGTGGTGCAGTGGGCGCCCTGCTGGTG TACGACATCGCCAAGCACCTGACCTATGAGAACGTGGAGCGCTGGCTGAAGGAGCTGCGGGACCACGCAGACAGCAACATCGTCATCATG CTGGTGGGCAACAAGAGTGACCTGCGCCACCTGCGGGCTGTGCCCACTGACGAGGCCCGCGCCTTCGCAGAAAAGAACAACTTGTCCTTC ATCGAGACCTCAGCCTTGGATTCCACTAACGTAGAGGAAGCATTCAAGAACATCCTCACAGGTGGCCGGGGACCAGATGGGTGTGGGTAG GGCACCAGCCAGGCAGGGTGGAACACGGCCTCTGAACCTTCGCTTGTTTTGTTCGTTTGCTTGTTTTTTTCTTTTTTTTGTCGGGGCAGG ATGGATTTTTGCTCTTTGCCCAGGCTGGAGTGTGGTGGCTCGATCTCAGCTTACTGCAACCTCCGCCTTCCAGGTTCAGGCAATTCTCCT GCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCTGCCACCACACCCGCTAATTTTTGTAATTTTTAGTAGAGACAGGATTTCACAAT GTTGTCCAGGTTGATCTCGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGCTGTGGACAAAGAAAATTTGGATGCTAAA ATTTCTAGCTTGACCAGTGAGATTATGAAACTTGAAAAAGAGGTCACTCAAATAAAAGACAGAAGTTTACCTGCTGTGGTAAGAGAGAAT GCCCAGTTATTGAATATGCCAGTGGTAAAGGGAGATTTTGATCTGCAGATTGCTAAACAAGATTATTATACAGCAAGACAAGAGTTAGTT TTAAATCAATTAATAAAACAAAAGGCATCATTTGAACTTCTACAGTTATCATATGAAATTGAATTAAGAAAGCATCGGGACATATATCGT CAACTTGAAAATTTGGTTCAAGAACTTAGTCAAAGTAACATGATGCTCTACAAGCAATTAGAAATGTTAACAGATCCATCAGTTTCTCAA CAGATAAATCCAAGGAATACCATTGATACTAAGGATTATTCTACTCATAGGCTTTACCAAGTTTTGGAGGGAGAGAATAAGAAAAAAGAA >In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000243706_chr4_2240770_-_1773nt ATGGGGACCCGGGACGACGAGTACGACTACCTATTCAAAGTGGTGCTCATCGGGGACTCAGGCGTGGGCAAGAGCAACCTGCTGTCGCGC TTCACCCGCAACGAGTTCAACCTGGAGAGCAAGAGCACCATCGGCGTGGAGTTCGCCACCCGCAGCATCCAGGTGGACGGCAAGACCATC AAGGCGCAGATCTGGGACACCGCTGGCCAGGAGCGCTACCGCGCCATCACCTCCGCGTACTACCGTGGTGCAGTGGGCGCCCTGCTGGTG TACGACATCGCCAAGCACCTGACCTATGAGAACGTGGAGCGCTGGCTGAAGGAGCTGCGGGACCACGCAGACAGCAACATCGTCATCATG CTGGTGGGCAACAAGAGTGACCTGCGCCACCTGCGGGCTGTGCCCACTGACGAGGCCCGCGCCTTCGCAGAAAAGAACAACTTGTCCTTC ATCGAGACCTCAGCCTTGGATTCCACTAACGTAGAGGAAGCATTCAAGAACATCCTCACAGGTGGCCGGGGACCAGATGGGTGTGGGTAG GGCACCAGCCAGGCAGGGTGGAACACGGCCTCTGAACCTTCGCTTGTTTTGTTCGTTTGCTTGTTTTTTTCTTTTTTTTGTCGGGGCAGG ATGGATTTTTGCTCTTTGCCCAGGCTGGAGTGTGGTGGCTCGATCTCAGCTTACTGCAACCTCCGCCTTCCAGGTTCAGGCAATTCTCCT GCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCTGCCACCACACCCGCTAATTTTTGTAATTTTTAGTAGAGACAGGATTTCACAAT GTTGTCCAGGTTGATCTCGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGCTGTGGACAAAGAAAATTTGGATGCTAAA ATTTCTAGCTTGACCAGTGAGATTATGAAACTTGAAAAAGAGGTCACTCAAATAAAAGACAGAAGTTTACCTGCTGTGGTAAGAGAGAAT GCCCAGTTATTGAATATGCCAGTGGTAAAGGGAGATTTTGATCTGCAGATTGCTAAACAAGATTATTATACAGCAAGACAAGAGTTAGTT TTAAATCAATTAATAAAACAAAAGGCATCATTTGAACTTCTACAGTTATCATATGAAATTGAATTAAGAAAGCATCGGGACATATATCGT CAACTTGAAAATTTGGTTCAAGAACTTAGTCAAAGTAACATGATGCTCTACAAGCAATTAGAAATGTTAACAGATCCATCAGTTTCTCAA CAGATAAATCCAAGGAATACCATTGATACTAAGGATTATTCTACTCATAGGCTTTACCAAGTTTTGGAGGGAGAGAATAAGAAAAAAGAA TTGTTTCTAACTCATGGAAACCTTGAGGAAGTGGCTGAGAAATTGAAACAGAATATTTCTTTAGTACAAGATCAGTTGGCAGTATCTGCT CAAGAACATTCTTTCTTTCTGTCCAAACGGAATAAGGATGTGGACATGCTTTGTGATACTTTGTATCAAGGAGGAAATCAGCTTTTGCTT AGTGATCAGGAGTTAACAGAGCAGTTTCATAAAGTTGAATCTCAACTGAATAAGCTAAATCATCTCCTCACTGATATTCTTGCTGATGTG AAGACAAAAAGAAAAACTTTGGCAAATAATAAATTACATCAAATGGAAAGAGAATTCTATGTATATTTTTTAAAAGATGAAGATTATCTG >In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000443786_chr4_2240770_-_1773nt ATGGGGACCCGGGACGACGAGTACGACTACCTATTCAAAGTGGTGCTCATCGGGGACTCAGGCGTGGGCAAGAGCAACCTGCTGTCGCGC TTCACCCGCAACGAGTTCAACCTGGAGAGCAAGAGCACCATCGGCGTGGAGTTCGCCACCCGCAGCATCCAGGTGGACGGCAAGACCATC AAGGCGCAGATCTGGGACACCGCTGGCCAGGAGCGCTACCGCGCCATCACCTCCGCGTACTACCGTGGTGCAGTGGGCGCCCTGCTGGTG TACGACATCGCCAAGCACCTGACCTATGAGAACGTGGAGCGCTGGCTGAAGGAGCTGCGGGACCACGCAGACAGCAACATCGTCATCATG CTGGTGGGCAACAAGAGTGACCTGCGCCACCTGCGGGCTGTGCCCACTGACGAGGCCCGCGCCTTCGCAGAAAAGAACAACTTGTCCTTC ATCGAGACCTCAGCCTTGGATTCCACTAACGTAGAGGAAGCATTCAAGAACATCCTCACAGGTGGCCGGGGACCAGATGGGTGTGGGTAG GGCACCAGCCAGGCAGGGTGGAACACGGCCTCTGAACCTTCGCTTGTTTTGTTCGTTTGCTTGTTTTTTTCTTTTTTTTGTCGGGGCAGG ATGGATTTTTGCTCTTTGCCCAGGCTGGAGTGTGGTGGCTCGATCTCAGCTTACTGCAACCTCCGCCTTCCAGGTTCAGGCAATTCTCCT GCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCTGCCACCACACCCGCTAATTTTTGTAATTTTTAGTAGAGACAGGATTTCACAAT GTTGTCCAGGTTGATCTCGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGCTGTGGACAAAGAAAATTTGGATGCTAAA ATTTCTAGCTTGACCAGTGAGATTATGAAACTTGAAAAAGAGGTCACTCAAATAAAAGACAGAAGTTTACCTGCTGTGGTAAGAGAGAAT GCCCAGTTATTGAATATGCCAGTGGTAAAGGGAGATTTTGATCTGCAGATTGCTAAACAAGATTATTATACAGCAAGACAAGAGTTAGTT TTAAATCAATTAATAAAACAAAAGGCATCATTTGAACTTCTACAGTTATCATATGAAATTGAATTAAGAAAGCATCGGGACATATATCGT CAACTTGAAAATTTGGTTCAAGAACTTAGTCAAAGTAACATGATGCTCTACAAGCAATTAGAAATGTTAACAGATCCATCAGTTTCTCAA CAGATAAATCCAAGGAATACCATTGATACTAAGGATTATTCTACTCATAGGCTTTACCAAGTTTTGGAGGGAGAGAATAAGAAAAAAGAA TTGTTTCTAACTCATGGAAACCTTGAGGAAGTGGCTGAGAAATTGAAACAGAATATTTCTTTAGTACAAGATCAGTTGGCAGTATCTGCT CAAGAACATTCTTTCTTTCTGTCCAAACGGAATAAGGATGTGGACATGCTTTGTGATACTTTGTATCAAGGAGGAAATCAGCTTTTGCTT AGTGATCAGGAGTTAACAGAGCAGTTTCATAAAGTTGAATCTCAACTGAATAAGCTAAATCATCTCCTCACTGATATTCTTGCTGATGTG AAGACAAAAAGAAAAACTTTGGCAAATAATAAATTACATCAAATGGAAAGAGAATTCTATGTATATTTTTTAAAAGATGAAGATTATCTG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000506763_chr4_2240770_-_2476nt GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGTGCTCATCGGGGACTCAGGCGTGGGCAAGAGCAACCTGC TGTCGCGCTTCACCCGCAACGAGTTCAACCTGGAGAGCAAGAGCACCATCGGCGTGGAGTTCGCCACCCGCAGCATCCAGGTGGACGGCA AGACCATCAAGGCGCAGATCTGGGACACCGCTGGCCAGGAGCGCTACCGCGCCATCACCTCCGCGTACTACCGTGGTGCAGTGGGCGCCC TGCTGGTGTACGACATCGCCAAGCACCTGACCTATGAGAACGTGGAGCGCTGGCTGAAGGAGCTGCGGGACCACGCAGACAGCAACATCG TCATCATGCTGGTGGGCAACAAGAGTGACCTGCGCCACCTGCGGGCTGTGCCCACTGACGAGGCCCGCGCCTTCGCAGAAAAGAACAACT TGTCCTTCATCGAGACCTCAGCCTTGGATTCCACTAACGTAGAGGAAGCATTCAAGAACATCCTCACAGGTGGCCGGGGACCAGATGGGT GTGGGTAGGGCACCAGCCAGGCAGGGTGGAACACGGCCTCTGAACCTTCGCTTGTTTTGTTCGTTTGCTTGTTTTTTTCTTTTTTTTGTC GGGGCAGGATGGATTTTTGCTCTTTGCCCAGGCTGGAGTGTGGTGGCTCGATCTCAGCTTACTGCAACCTCCGCCTTCCAGGTTCAGGCA ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCTGCCACCACACCCGCTAATTTTTGTAATTTTTAGTAGAGACAGGAT TTCACAATGTTGTCCAGGTTGATCTCGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGCTGTGGACAAAGAAAATTTGG ATGCTAAAATTTCTAGCTTGACCAGTGAGATTATGAAACTTGAAAAAGAGGTCACTCAAATAAAAGACAGAAGTTTACCTGCTGTGGTAA GAGAGAATGCCCAGTTATTGAATATGCCAGTGGTAAAGGGAGATTTTGATCTGCAGATTGCTAAACAAGATTATTATACAGCAAGACAAG AGTTAGTTTTAAATCAATTAATAAAACAAAAGGCATCATTTGAACTTCTACAGTTATCATATGAAATTGAATTAAGAAAGCATCGGGACA TATATCGTCAACTTGAAAATTTGGTTCAAGAACTTAGTCAAAGTAACATGATGCTCTACAAGCAATTAGAAATGTTAACAGATCCATCAG TTTCTCAACAGATAAATCCAAGGAATACCATTGATACTAAGGATTATTCTACTCATAGGCTTTACCAAGTTTTGGAGGGAGAGAATAAGA AAAAAGAATTGTTTCTAACTCATGGAAACCTTGAGGAAGTGGCTGAGGCAGGAGAATGGCATGAACCCAGGAGGCGGGGCTTGCAGTGAG CTGAGGTCTCCAGCGTGGGCGACAGAGTGAGACTCTATCTCAAAAAAAAAAAAAAAAAAAAGTGAAAGCAGTGATATGCTCACAAATGTC ACTGAAATGTTTATAACATCAGGGCTTTTGGTGTTTTTTTGTTTTGTTTTTTGTTGGTGTTTTTTTTTTTTTTTTGCTACTAGCAAAGCA GTTTTTATTTTAAATTTGCAAGCCTGGGCCAATAGTTTGTGGTTGGTTTCTCTTTCTACAAAATAAGGTATAAGTGAGTGAGATATAATT GAGTAATGAAATTGCATTGAAATAATTGAGAGTATTGCCGAATATTAGCACAAAAGCTCTTATAAACACATCTTGATTAAGATACATTTG CACTTAACGTTTTGATCCATTCATATTGAGGCATCTGTTGCTTATATACTTTATTATAGTAGAAGTCACTAATAAACTGGTAAGAATTTT TGAGTGTGAATTACATGCCTAGCAATTGATAGTGTAAGACACTATCATAATCACATTATTCCATATTTTTTTGAATAATAGAGGGTGCAT ACTTGACAGAGGTGGAAATATACTCCCCTTCAAAAACCGGTAAGAATAATGAAATGCCTCTGGCAGCTATAATATGAGGCTCTGATGAAA AATTTACGACAGTCAGTCCATCTCATATAAGCTCTTATTGTTGTTCTAAAATACATTGTTAATGCCTGGGACGATCACTTGAGCCCAGGA GTTCGAGTCCAGCCTAGGCAACATAGCAAGATCTCATCTCTGAAAATAAAATACCCCGTTAAAATTCTGGCTTTTGTTTGTTAAGGTTAT TGAGAAGGTAATAGAAAAAGATATGATACTACTTTTCTCTCTTGGATTTGTAAAAATAGTGGAATTTTCATAAGGATTTTGTATTTTCTA >In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000243706_chr4_2240770_-_5449nt GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGTGCTCATCGGGGACTCAGGCGTGGGCAAGAGCAACCTGC TGTCGCGCTTCACCCGCAACGAGTTCAACCTGGAGAGCAAGAGCACCATCGGCGTGGAGTTCGCCACCCGCAGCATCCAGGTGGACGGCA AGACCATCAAGGCGCAGATCTGGGACACCGCTGGCCAGGAGCGCTACCGCGCCATCACCTCCGCGTACTACCGTGGTGCAGTGGGCGCCC TGCTGGTGTACGACATCGCCAAGCACCTGACCTATGAGAACGTGGAGCGCTGGCTGAAGGAGCTGCGGGACCACGCAGACAGCAACATCG TCATCATGCTGGTGGGCAACAAGAGTGACCTGCGCCACCTGCGGGCTGTGCCCACTGACGAGGCCCGCGCCTTCGCAGAAAAGAACAACT TGTCCTTCATCGAGACCTCAGCCTTGGATTCCACTAACGTAGAGGAAGCATTCAAGAACATCCTCACAGGTGGCCGGGGACCAGATGGGT GTGGGTAGGGCACCAGCCAGGCAGGGTGGAACACGGCCTCTGAACCTTCGCTTGTTTTGTTCGTTTGCTTGTTTTTTTCTTTTTTTTGTC GGGGCAGGATGGATTTTTGCTCTTTGCCCAGGCTGGAGTGTGGTGGCTCGATCTCAGCTTACTGCAACCTCCGCCTTCCAGGTTCAGGCA ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCTGCCACCACACCCGCTAATTTTTGTAATTTTTAGTAGAGACAGGAT TTCACAATGTTGTCCAGGTTGATCTCGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGCTGTGGACAAAGAAAATTTGG ATGCTAAAATTTCTAGCTTGACCAGTGAGATTATGAAACTTGAAAAAGAGGTCACTCAAATAAAAGACAGAAGTTTACCTGCTGTGGTAA GAGAGAATGCCCAGTTATTGAATATGCCAGTGGTAAAGGGAGATTTTGATCTGCAGATTGCTAAACAAGATTATTATACAGCAAGACAAG AGTTAGTTTTAAATCAATTAATAAAACAAAAGGCATCATTTGAACTTCTACAGTTATCATATGAAATTGAATTAAGAAAGCATCGGGACA TATATCGTCAACTTGAAAATTTGGTTCAAGAACTTAGTCAAAGTAACATGATGCTCTACAAGCAATTAGAAATGTTAACAGATCCATCAG TTTCTCAACAGATAAATCCAAGGAATACCATTGATACTAAGGATTATTCTACTCATAGGCTTTACCAAGTTTTGGAGGGAGAGAATAAGA AAAAAGAATTGTTTCTAACTCATGGAAACCTTGAGGAAGTGGCTGAGAAATTGAAACAGAATATTTCTTTAGTACAAGATCAGTTGGCAG TATCTGCTCAAGAACATTCTTTCTTTCTGTCCAAACGGAATAAGGATGTGGACATGCTTTGTGATACTTTGTATCAAGGAGGAAATCAGC TTTTGCTTAGTGATCAGGAGTTAACAGAGCAGTTTCATAAAGTTGAATCTCAACTGAATAAGCTAAATCATCTCCTCACTGATATTCTTG CTGATGTGAAGACAAAAAGAAAAACTTTGGCAAATAATAAATTACATCAAATGGAAAGAGAATTCTATGTATATTTTTTAAAAGATGAAG ATTATCTGAAAGATATTGTGGAGAATTTAGAAACTCAATCAAAGATTAAGGCTGTTAGTCTTGAAGATTGAAAATTACTGAAAACTGAAT CTTTATTACGTGTCCTCTTTTATTTATTAGAAGACTGTGTATAATAAACACTACTAAATTTTTAAAATTTGAGGTCAATGGAACATTTAA TTTGATGAATTGAACTATTATATTAATTTGTCTTTTTTCTCATGTAGTACATTCAGAATACCAGTGCTTTTTATGACTTGAGCATGTGTT TAGTGGTACTTAGTCCTGGTAATTTTTTACTTACAGGGAAAAAGCATTATTACATAATGCAAATATTTTTTAATATAGTTATCTCTCTCC TTTTTAGAAATAGAAATTTTCTGCCGTTAAATTTTTTTTTGAGATAGAGTCTCACTCTGTCTCCAGGCTGGAATGCAGTGGCACGATCTT GGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCGCACACCGCCACAC CCAGCTAATTTTTTTGTATTTTAGTAGAAAAGGGGTTTCACCATGTTGGCCAGGATGGTCTCAATCTCTTGACCTCTTGATCCCCTCTCC CGGCCTCCCAAAGTGCCGGAATTACAGGCATGAGCCACCACGCTCAGCCGCTATTAAATATTTTAAAATGTGTAGAACTTCTAGTCAGCA TTTTTAAATCTGTAGACCTTAATATGTGAAATAGCCAAGTCCCCTCATGTTTGACTGTCAAATAAAATTCTGCTGCTCAAATTGTATTCC TCCATAATTCCCTGCTATAGACCTTTAGGCTGTTTTAATGTCCCTACTTGTACCACAGAGTATTAGGACTTCCTTGGCCTGCCTGCATTC ATTTTAGAGTCTGAATTCTGGGGACTCAAAAGTTTCTACAAGACAGCTGAGCAGTGCTTTGACTTTAATGTGACTTACACATCATAAATG ACTTTCAAATGAAATTTGAATTTCAAAATTCTGTAAAAGTGGTTGCTCAAAAGATGTATGATACTATTTTAATCAGTTTAAGAGCAAAAA TGTCTAATTGTATTTAACAATGGTATTTGGGCAGCCAGAAAATATTTTAAGCGTTGCTCTAAAATAATTTGAAGTAGCTCATCTGTTATT ACATCAGATGCTTCTTGAGTGCCCAATTTATACATGGCCTGTGGTAAATACCATGTGAGCTTTGTAGGAATACCTTTAAGAATATTCCTC ACCTGTTCGTAATATGGAATGCCAATCTAAAAACTACATGTTTTGGGTGGTCTTTATGGAATTTTTTAGCTATAACCATCAGAAAACAGG CATACCTAGATGACAGATGAACCTTCTTGATTTTTGAAACCCATTGAACAAAAATATTTTGCCAATTATTGTGTTTATGTTATTTAAAAT TTTATGTAAACCTTAATTTTGTAGCAGTAAATTTTGTTTAAGATTTTGCTATCAGCTCCCTATCACCTGAGCAACTTTTTTTTTGTTGTA TATGTTTTTTTCTATTCTATTTCGGAATAGAGAATTTACTTAAAATTTTTATTTTCTCCAAAAATGTGGAAAATATGTCACCTGGTTTCC TGGTTTATGGTAGCATATTCTGTTTAAATTAGTGTCACATATTTAGATGTGTGGCCAGACGCTTGATTTATTAGTTAATTTTTGAGACAG AGTCTAACTGTGTCACTCAGGCTGGAGTTCAGTGGAATGATCTCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGTGATTCTCCTGCT TCAGCCTCCTGAGTAGATGGGATTGTAGGCGTGCACCACTGCACCTGGCTAATTTTTGTATTTTCAGTAGAGACGGGGTTTCACCATGTT GGTCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCTACCCGCCTTGGCCTTCCATAGTGCTGGCATTACAGGTGTAAGCCACCATGCC CCTGCCCAGATGCTTGATTTATACTGTCCCCACCCAAACCTTGACTTGCTCAGCCCAGGGGGCCAGCAGGGCAGATCAAGGCACGGATGG TAGTTGTGTGTCTGCCGTAATTACCCAAGTTACTTATAATCGTTGTGTTACTAGGTAGGTTTATTTGAAGATTTATTTATTTATTTATTT ATTTTTTATTTTTTGAGACGGAGTTTCACTCTTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTCAGCTCACTGCAACCTCTGCCTTCT GGGTTCACGTGATTCTCCTGCCTCAGGCCTCCCGAGTAGCTGGGATTACAGGTGCCACCATGCCTGGTTAATTTTTTGTATTTTTAGTAG AGACGGGGTTTCATCATGTTGGCCAGGTTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCGCCTCAGTCTACCAAAGTGCAGGGATCA CAGGCATGAGCTTCCGCGCTCAGCCTATTTGAAGATTTAATAACATTTTTCAAACCTCAGGATGTATTTGAGTAGATTGCTTCTAAATTG GTCACCTAGAAAATAAGTTATCTATTTACTATGATACCTGGATTAAGCCTCTAGCTATTTTGCTTTTTTCTTTCTATCTATATTATTGGA TGATTGATGCCTATTTTCTGTGGTTATGAATATAGACATTTTAAATGAAAGTTGGTATATAAATTTTTGAAAATAATTGTATTTCCTGTT TTATAGTCTTAGGATTAATATATGGGATTTATCTTATGTTAATCTTACATTTAGGATTTTGTGAAAATGGAAAATTATGAGGCATTGGTA GGCTTTGATCTCTGTAATACACCGCTCTCCAGTGTTGCTCAGAAGATTATGTCTGCTATGCATTCAGGTGATTTAGTGGATTCTAAGACT TGGGGAAAGAGTACAGAGAGTAAGTAATTTTTATGAACCTTTCTTTCTCTTGATACTTTGAATGTTAATTGTTCTAAAGACTAAGAATTG AAAATGGAATGCATGTAGACAGATGAAGCCCAGCTCCCGCCCCTTTTACACTCATTCAGTGCAGACTGAGCTTCTGCTTGCTAACTTTCG TGTTCCCTTAACCTTCATTGCTTTAAAAATGTAACACTCTCTTCCTTATTCCAGGTATTTCTGTCAAACATTCCCTTAGAATCTGGATCA GGTATTTTAGTATTTTCAAAAGAGATGCTTTAATCTTGGTTCTCAGGTCATCAAACCTGTACATAGTATTTGCTATTTTGTGTGGTGAAC AAGAGATATGTTTTTGACAATATGTGTATTGTGCTGCTATAGAAATGTAAACTCTTAGGTGGCAAGGATTATTGGATCAGTGTATATGGA TTTATGATGTGGTATAATAGTAAAAGCAGTGGGGCCGGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTCGGCG ATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTAAAACACTGTCTCTACTAAAAATACAAAAAATTAGCTGGGAGTGGTGG TAGGCGCCTGTAGTCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCATGAACCCAGGAGGCGGGGCTTGCAGTGAGCTGAGGTCTCCA >In-frame_RAB11B_ENST00000594216_chr19_8467449_+_HAUS3_ENST00000443786_chr4_2240770_-_1957nt GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGTGCTCATCGGGGACTCAGGCGTGGGCAAGAGCAACCTGC TGTCGCGCTTCACCCGCAACGAGTTCAACCTGGAGAGCAAGAGCACCATCGGCGTGGAGTTCGCCACCCGCAGCATCCAGGTGGACGGCA AGACCATCAAGGCGCAGATCTGGGACACCGCTGGCCAGGAGCGCTACCGCGCCATCACCTCCGCGTACTACCGTGGTGCAGTGGGCGCCC TGCTGGTGTACGACATCGCCAAGCACCTGACCTATGAGAACGTGGAGCGCTGGCTGAAGGAGCTGCGGGACCACGCAGACAGCAACATCG TCATCATGCTGGTGGGCAACAAGAGTGACCTGCGCCACCTGCGGGCTGTGCCCACTGACGAGGCCCGCGCCTTCGCAGAAAAGAACAACT TGTCCTTCATCGAGACCTCAGCCTTGGATTCCACTAACGTAGAGGAAGCATTCAAGAACATCCTCACAGGTGGCCGGGGACCAGATGGGT GTGGGTAGGGCACCAGCCAGGCAGGGTGGAACACGGCCTCTGAACCTTCGCTTGTTTTGTTCGTTTGCTTGTTTTTTTCTTTTTTTTGTC GGGGCAGGATGGATTTTTGCTCTTTGCCCAGGCTGGAGTGTGGTGGCTCGATCTCAGCTTACTGCAACCTCCGCCTTCCAGGTTCAGGCA ATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGCCTGCCACCACACCCGCTAATTTTTGTAATTTTTAGTAGAGACAGGAT TTCACAATGTTGTCCAGGTTGATCTCGAACTCCTGGGCTCAAGTGATCCTCCTGCCTCAGCCTCCCAAGCTGTGGACAAAGAAAATTTGG ATGCTAAAATTTCTAGCTTGACCAGTGAGATTATGAAACTTGAAAAAGAGGTCACTCAAATAAAAGACAGAAGTTTACCTGCTGTGGTAA GAGAGAATGCCCAGTTATTGAATATGCCAGTGGTAAAGGGAGATTTTGATCTGCAGATTGCTAAACAAGATTATTATACAGCAAGACAAG AGTTAGTTTTAAATCAATTAATAAAACAAAAGGCATCATTTGAACTTCTACAGTTATCATATGAAATTGAATTAAGAAAGCATCGGGACA TATATCGTCAACTTGAAAATTTGGTTCAAGAACTTAGTCAAAGTAACATGATGCTCTACAAGCAATTAGAAATGTTAACAGATCCATCAG TTTCTCAACAGATAAATCCAAGGAATACCATTGATACTAAGGATTATTCTACTCATAGGCTTTACCAAGTTTTGGAGGGAGAGAATAAGA AAAAAGAATTGTTTCTAACTCATGGAAACCTTGAGGAAGTGGCTGAGAAATTGAAACAGAATATTTCTTTAGTACAAGATCAGTTGGCAG TATCTGCTCAAGAACATTCTTTCTTTCTGTCCAAACGGAATAAGGATGTGGACATGCTTTGTGATACTTTGTATCAAGGAGGAAATCAGC TTTTGCTTAGTGATCAGGAGTTAACAGAGCAGTTTCATAAAGTTGAATCTCAACTGAATAAGCTAAATCATCTCCTCACTGATATTCTTG CTGATGTGAAGACAAAAAGAAAAACTTTGGCAAATAATAAATTACATCAAATGGAAAGAGAATTCTATGTATATTTTTTAAAAGATGAAG ATTATCTGAAAGATATTGTGGAGAATTTAGAAACTCAATCAAAGATTAAGGCTGTTAGTCTTGAAGATTGAAAATTACTGAAAACTGAAT |
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FusionGenePPI for RAB11B_HAUS3 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| RAB11B | RAB11FIP1, RAB11FIP2, RAB11FIP3, RAB11FIP5, H2AFX, CDK2, APP, GDI1, RAB1A, GDI2, RAB11A, RAB1B, RAB8A, RAB7A, ATP6V1H, HNRNPUL1, DDX28, ABCC2, HNRNPUL2, VCP, ATP4A, MYO5B, RPA3, RPA2, RPA1, OPTN, CUL7, WDR44, CHML, CHM, SH3BP5L, RAB25, SH3BP5, S100A3, SERPINB5, SELENBP1, LYG2, LRRC15, DNPEP, HEPHL1, LGALS3, VSIG8, DSG4, CALML3, DUSP14, PLCD1, PADI3, HIST1H2AG, FAM26D, TRIM27, PROCR, ETNK2, FAM217B, DUT, GNAI3, NUTF2, PHB2, ARF1, CDC42, PGAM1, RAB5A, RAB6A, UAP1L1, RAB5B, RAB5C, OFD1, CNTRL, SCLT1, TMEM17, IKBKG, GOLT1B, LRRK2, CDH1, RBM42, BSPRY, IFIT2, SCEL, NT5C3A | HAUS3 | HAUS6, KDM1A, HAUS2, C19orf57, TXLNB, TXLNA, HAUS7, COG3, MED4, SSX2IP, OFD1, PCM1, CEP170, KIAA0753, CEP104, CEP162, CEP290, CEP120, CEP152, SPICE1, CEP128, CEP135, CEP44, CEP63, CEP89, CNTRL, FBF1, NIN, ODF2, RPGRIP1L, POC5, LCA5, SASS6, CENPJ, XPO1, SMC1A, SYCE3, CDC16, C6orf141, CRYL1 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for RAB11B_HAUS3 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for RAB11B_HAUS3 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | RAB11B | C0019693 | HIV Infections | 1 | CTD_human |
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