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Fusion gene ID: 2982 |
FusionGeneSummary for ASH2L_C8orf86 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ASH2L_C8orf86 | Fusion gene ID: 2982 | Hgene | Tgene | Gene symbol | ASH2L | C8orf86 | Gene ID | 9070 | 389649 |
| Gene name | ASH2 like, histone lysine methyltransferase complex subunit | chromosome 8 open reading frame 86 | |
| Synonyms | ASH2|ASH2L1|ASH2L2|Bre2 | - | |
| Cytomap | 8p11.23 | 8p11.22 | |
| Type of gene | protein-coding | protein-coding | |
| Description | set1/Ash2 histone methyltransferase complex subunit ASH2ASH2-like proteinash2 (absent, small, or homeotic)-like | uncharacterized protein C8orf86 | |
| Modification date | 20180523 | 20180329 | |
| UniProtAcc | Q9UBL3 | Q6ZUL3 | |
| Ensembl transtripts involved in fusion gene | ENST00000343823, ENST00000250635, ENST00000545394, ENST00000428278, ENST00000521652, ENST00000524263, | ENST00000358138, ENST00000437935, | |
| Fusion gene scores | * DoF score | 8 X 6 X 5=240 | 3 X 2 X 2=12 |
| # samples | 8 | 2 | |
| ** MAII score | log2(8/240*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/12*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: ASH2L [Title/Abstract] AND C8orf86 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | Transcription factor involved fusion gene, inframe and retained DNA-binding domain. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ASH2L | GO:0006974 | cellular response to DNA damage stimulus | 17500065 |
| Hgene | ASH2L | GO:0043627 | response to estrogen | 16603732 |
| Hgene | ASH2L | GO:0051568 | histone H3-K4 methylation | 17355966|19556245 |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | RV | HNSC | TCGA-CR-7364-01A | ASH2L | chr8 | 37968351 | + | C8orf86 | chr8 | 38374030 | - |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000343823 | ENST00000358138 | ASH2L | chr8 | 37968351 | + | C8orf86 | chr8 | 38374030 | - |
| 5CDS-intron | ENST00000343823 | ENST00000437935 | ASH2L | chr8 | 37968351 | + | C8orf86 | chr8 | 38374030 | - |
| In-frame | ENST00000250635 | ENST00000358138 | ASH2L | chr8 | 37968351 | + | C8orf86 | chr8 | 38374030 | - |
| 5CDS-intron | ENST00000250635 | ENST00000437935 | ASH2L | chr8 | 37968351 | + | C8orf86 | chr8 | 38374030 | - |
| In-frame | ENST00000545394 | ENST00000358138 | ASH2L | chr8 | 37968351 | + | C8orf86 | chr8 | 38374030 | - |
| 5CDS-intron | ENST00000545394 | ENST00000437935 | ASH2L | chr8 | 37968351 | + | C8orf86 | chr8 | 38374030 | - |
| In-frame | ENST00000428278 | ENST00000358138 | ASH2L | chr8 | 37968351 | + | C8orf86 | chr8 | 38374030 | - |
| 5CDS-intron | ENST00000428278 | ENST00000437935 | ASH2L | chr8 | 37968351 | + | C8orf86 | chr8 | 38374030 | - |
| In-frame | ENST00000521652 | ENST00000358138 | ASH2L | chr8 | 37968351 | + | C8orf86 | chr8 | 38374030 | - |
| 5CDS-intron | ENST00000521652 | ENST00000437935 | ASH2L | chr8 | 37968351 | + | C8orf86 | chr8 | 38374030 | - |
| 3UTR-3CDS | ENST00000524263 | ENST00000358138 | ASH2L | chr8 | 37968351 | + | C8orf86 | chr8 | 38374030 | - |
| 3UTR-intron | ENST00000524263 | ENST00000437935 | ASH2L | chr8 | 37968351 | + | C8orf86 | chr8 | 38374030 | - |
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FusionProtFeatures for ASH2L_C8orf86 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ASH2L | C8orf86 |
| Component of the Set1/Ash2 histone methyltransferase(HMT) complex, a complex that specifically methylates 'Lys-4' ofhistone H3, but not if the neighboring 'Lys-9' residue is alreadymethylated. As part of the MLL1/MLL complex it is involved inmethylation and dimethylation at 'Lys-4' of histone H3. Mayfunction as a transcriptional regulator. May play a role inhematopoiesis. {ECO:0000269|PubMed:12670868,ECO:0000269|PubMed:19556245}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ASH2L | chr8:37968351 | chr8:38374030 | ENST00000343823 | + | 5 | 16 | 67_177 | 195 | 629 | Region | Note=DNA-binding |
| Hgene | ASH2L | chr8:37968351 | chr8:38374030 | ENST00000250635 | + | 5 | 15 | 1_66 | 101 | 502 | Zinc finger | Note=PHD-type%3B atypical |
| Hgene | ASH2L | chr8:37968351 | chr8:38374030 | ENST00000343823 | + | 5 | 16 | 117_150 | 195 | 629 | Zinc finger | Note=C4-type |
| Hgene | ASH2L | chr8:37968351 | chr8:38374030 | ENST00000343823 | + | 5 | 16 | 1_66 | 195 | 629 | Zinc finger | Note=PHD-type%3B atypical |
| Hgene | ASH2L | chr8:37968351 | chr8:38374030 | ENST00000428278 | + | 5 | 16 | 1_66 | 101 | 535 | Zinc finger | Note=PHD-type%3B atypical |
| Hgene | ASH2L | chr8:37968351 | chr8:38374030 | ENST00000521652 | + | 5 | 15 | 1_66 | 101 | 502 | Zinc finger | Note=PHD-type%3B atypical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | >ASH2L | chr8:37968351 | chr8:38374030 | ENST00000250635 | + | 5 | 15 | 360_583 | 101 | 502 | Domain | B30.2/SPRY |
| Hgene | >ASH2L | chr8:37968351 | chr8:38374030 | ENST00000343823 | + | 5 | 16 | 360_583 | 195 | 629 | Domain | B30.2/SPRY |
| Hgene | >ASH2L | chr8:37968351 | chr8:38374030 | ENST00000428278 | + | 5 | 16 | 360_583 | 101 | 535 | Domain | B30.2/SPRY |
| Hgene | >ASH2L | chr8:37968351 | chr8:38374030 | ENST00000521652 | + | 5 | 15 | 360_583 | 101 | 502 | Domain | B30.2/SPRY |
| Hgene | >ASH2L | chr8:37968351 | chr8:38374030 | ENST00000250635 | + | 5 | 15 | 67_177 | 101 | 502 | Region | Note=DNA-binding |
| Hgene | >ASH2L | chr8:37968351 | chr8:38374030 | ENST00000428278 | + | 5 | 16 | 67_177 | 101 | 535 | Region | Note=DNA-binding |
| Hgene | >ASH2L | chr8:37968351 | chr8:38374030 | ENST00000521652 | + | 5 | 15 | 67_177 | 101 | 502 | Region | Note=DNA-binding |
| Hgene | >ASH2L | chr8:37968351 | chr8:38374030 | ENST00000250635 | + | 5 | 15 | 117_150 | 101 | 502 | Zinc finger | Note=C4-type |
| Hgene | >ASH2L | chr8:37968351 | chr8:38374030 | ENST00000428278 | + | 5 | 16 | 117_150 | 101 | 535 | Zinc finger | Note=C4-type |
| Hgene | >ASH2L | chr8:37968351 | chr8:38374030 | ENST00000521652 | + | 5 | 15 | 117_150 | 101 | 502 | Zinc finger | Note=C4-type |
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FusionGeneSequence for ASH2L_C8orf86 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_ASH2L_ENST00000343823_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_314aa MAAAGAGPGQEAGAGPGPGAVANATGAEEGEMKPVAAGAAAPPGEGISAAPTVEPSSGEAEGGEANLVDVSGGLETESSNGKDTLEGAGD TSEVMDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQS RTQDEHPKTMFSKDKAYENTGHWERLASVVSSKTQQPTVISHSSISITFSHYPPATLDSFLVLEPIKLFPVSSLRSPLCLNCGSCRESIR >In-frame_ASH2L_ENST00000250635_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_220aa MDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQD EHPKTMFSKDKAYENTGHWERLASVVSSKTQQPTVISHSSISITFSHYPPATLDSFLVLEPIKLFPVSSLRSPLCLNCGSCRESIRISGE >In-frame_ASH2L_ENST00000545394_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_175aa MTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQDEHPKTMFSKDKAYENTGHWERLASVVSSKTQQPTVISHSSISITF >In-frame_ASH2L_ENST00000428278_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_220aa MDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQD EHPKTMFSKDKAYENTGHWERLASVVSSKTQQPTVISHSSISITFSHYPPATLDSFLVLEPIKLFPVSSLRSPLCLNCGSCRESIRISGE >In-frame_ASH2L_ENST00000521652_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_220aa MDTQAGSVDEENGRQLGEVELQCGICTKWFTADTFGIDTSSCLPFMTNYSFHCNVCHHSGNTYFLRKQANLKEMCLSALANLTWQSRTQD EHPKTMFSKDKAYENTGHWERLASVVSSKTQQPTVISHSSISITFSHYPPATLDSFLVLEPIKLFPVSSLRSPLCLNCGSCRESIRISGE |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_ASH2L_ENST00000343823_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_942nt ATGGCGGCGGCAGGAGCAGGACCTGGCCAGGAAGCGGGTGCCGGGCCTGGCCCAGGAGCGGTCGCAAATGCAACAGGGGCAGAAGAGGGG GAGATGAAGCCGGTGGCAGCGGGAGCAGCCGCTCCTCCTGGAGAGGGGATCTCTGCTGCTCCGACAGTTGAGCCCAGTTCCGGGGAGGCT GAAGGCGGGGAGGCAAACTTGGTCGATGTAAGCGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAGAAGGTGCTGGGGAT ACATCAGAGGTGATGGATACTCAGGCGGGCTCCGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGT ACAAAATGGTTCACGGCTGACACATTTGGCATAGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGC CATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCC CGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGCTTATGAGAATACAGGCCACTGGGAGAGACTCGCATCTGTGGTT TCTTCAAAAACACAGCAGCCCACAGTGATCTCTCATTCTTCCATTTCTATCACATTCAGTCATTACCCTCCAGCCACACTGGACTCCTTT CTTGTCCTGGAACCTATCAAACTCTTTCCTGTCTCAAGCCTCCGCAGTCCTCTCTGCTTGAACTGTGGCTCCTGCAGAGAAAGCATCAGA ATCTCCGGGGAACTGATTGGAAATGCACATTCTCCAGCCCCGCCCAGAACTCCTGAATTAGAAACCCTGGGGTGGGACAAGCAAGCCGTG >In-frame_ASH2L_ENST00000250635_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_660nt ATGGATACTCAGGCGGGCTCCGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTC ACGGCTGACACATTTGGCATAGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGG AATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGAT GAACATCCGAAGACAATGTTCTCCAAAGATAAGGCTTATGAGAATACAGGCCACTGGGAGAGACTCGCATCTGTGGTTTCTTCAAAAACA CAGCAGCCCACAGTGATCTCTCATTCTTCCATTTCTATCACATTCAGTCATTACCCTCCAGCCACACTGGACTCCTTTCTTGTCCTGGAA CCTATCAAACTCTTTCCTGTCTCAAGCCTCCGCAGTCCTCTCTGCTTGAACTGTGGCTCCTGCAGAGAAAGCATCAGAATCTCCGGGGAA CTGATTGGAAATGCACATTCTCCAGCCCCGCCCAGAACTCCTGAATTAGAAACCCTGGGGTGGGACAAGCAAGCCGTGCTTTCTGGGGCA >In-frame_ASH2L_ENST00000545394_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_525nt ATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGC CTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGCTTATGAGAAT ACAGGCCACTGGGAGAGACTCGCATCTGTGGTTTCTTCAAAAACACAGCAGCCCACAGTGATCTCTCATTCTTCCATTTCTATCACATTC AGTCATTACCCTCCAGCCACACTGGACTCCTTTCTTGTCCTGGAACCTATCAAACTCTTTCCTGTCTCAAGCCTCCGCAGTCCTCTCTGC TTGAACTGTGGCTCCTGCAGAGAAAGCATCAGAATCTCCGGGGAACTGATTGGAAATGCACATTCTCCAGCCCCGCCCAGAACTCCTGAA >In-frame_ASH2L_ENST00000428278_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_660nt ATGGATACTCAGGCGGGCTCCGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTC ACGGCTGACACATTTGGCATAGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGG AATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGAT GAACATCCGAAGACAATGTTCTCCAAAGATAAGGCTTATGAGAATACAGGCCACTGGGAGAGACTCGCATCTGTGGTTTCTTCAAAAACA CAGCAGCCCACAGTGATCTCTCATTCTTCCATTTCTATCACATTCAGTCATTACCCTCCAGCCACACTGGACTCCTTTCTTGTCCTGGAA CCTATCAAACTCTTTCCTGTCTCAAGCCTCCGCAGTCCTCTCTGCTTGAACTGTGGCTCCTGCAGAGAAAGCATCAGAATCTCCGGGGAA CTGATTGGAAATGCACATTCTCCAGCCCCGCCCAGAACTCCTGAATTAGAAACCCTGGGGTGGGACAAGCAAGCCGTGCTTTCTGGGGCA >In-frame_ASH2L_ENST00000521652_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_660nt ATGGATACTCAGGCGGGCTCCGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTC ACGGCTGACACATTTGGCATAGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGG AATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGAT GAACATCCGAAGACAATGTTCTCCAAAGATAAGGCTTATGAGAATACAGGCCACTGGGAGAGACTCGCATCTGTGGTTTCTTCAAAAACA CAGCAGCCCACAGTGATCTCTCATTCTTCCATTTCTATCACATTCAGTCATTACCCTCCAGCCACACTGGACTCCTTTCTTGTCCTGGAA CCTATCAAACTCTTTCCTGTCTCAAGCCTCCGCAGTCCTCTCTGCTTGAACTGTGGCTCCTGCAGAGAAAGCATCAGAATCTCCGGGGAA CTGATTGGAAATGCACATTCTCCAGCCCCGCCCAGAACTCCTGAATTAGAAACCCTGGGGTGGGACAAGCAAGCCGTGCTTTCTGGGGCA |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_ASH2L_ENST00000343823_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_2804nt GCAGAATATCCAGTCGTAGCCACGAAAATACGCCGCGTCAGTCCCTGACTCGAAAGGAAGTCCTCCAGAGAGCCGCACTAACCATCTAGC TTCCTCCACCTTCAGCCTGCCAGGCCCGCGGCCACCGCCGGCGCGGGAGGCCGGCCCACCTCTGCCCGCGCGCCTGGCCTTAAAGCGGTC GTGGAATTATGCTTCCTCAGGCAGGCGGTGGACGCACCGCGGGCTTTTTCTGTTTGAAGACTACAGCGTCACACAGCAACGCGCGCGAGA GAAGAGAGTATTCTCGCGAGAAGTCCAGGGGTGGCCGTGATGGCGGCGGCAGGAGCAGGACCTGGCCAGGAAGCGGGTGCCGGGCCTGGC CCAGGAGCGGTCGCAAATGCAACAGGGGCAGAAGAGGGGGAGATGAAGCCGGTGGCAGCGGGAGCAGCCGCTCCTCCTGGAGAGGGGATC TCTGCTGCTCCGACAGTTGAGCCCAGTTCCGGGGAGGCTGAAGGCGGGGAGGCAAACTTGGTCGATGTAAGCGGTGGCTTGGAGACAGAA TCATCTAATGGAAAAGATACACTAGAAGGTGCTGGGGATACATCAGAGGTGATGGATACTCAGGCGGGCTCCGTGGATGAAGAGAATGGC CGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTCACGGCTGACACATTTGGCATAGATACCTCATCCTGTCTA CCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAA ATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGCTTAT GAGAATACAGGCCACTGGGAGAGACTCGCATCTGTGGTTTCTTCAAAAACACAGCAGCCCACAGTGATCTCTCATTCTTCCATTTCTATC ACATTCAGTCATTACCCTCCAGCCACACTGGACTCCTTTCTTGTCCTGGAACCTATCAAACTCTTTCCTGTCTCAAGCCTCCGCAGTCCT CTCTGCTTGAACTGTGGCTCCTGCAGAGAAAGCATCAGAATCTCCGGGGAACTGATTGGAAATGCACATTCTCCAGCCCCGCCCAGAACT CCTGAATTAGAAACCCTGGGGTGGGACAAGCAAGCCGTGCTTTCTGGGGCACAGGTGATTCTGGTGTGTGCTGAAGTTTAAGAACCACTG GCCGAGAACATTCTTAGGTCTGCTCTTCTTTTGCCCGGCCCCTCCCTCGCGGAGGAATTCCTTCTTATTCCTCTCTGAAGAGTGGCTGCT GCCAAAAAACGTTTGTGAGATGGCCTGGGTTTTCTTTGTTGATTTATCATTTAGTTTGGAAGAAATCAGAAGTCTCTTTAAGAAGCCAAT TTGAAACATTCACCCCATGGGAACAGTTCTGGATGAAGTCAGAAGATCTGGAGGCAGCGCAGTAACACACGTAGGTTTTCTGGCCATATG GACATTTCAGAGAAAACAACGCACAGAGGCCTGGAGCAGGTGAACTGGCTTAAGTAGAGAGAAACTAAGTCATTTGGGGATATTTAGCAC CTAATGTCAAGGCAGAAATGTCTAAGATGTAATTAACAGTTATATTCTAATCTCAATAGTAGCTAAGTACAGACTTAAACATAAGCCTGT ATATAACAAAATAACCCCAGGAGAACCAAAGAAAATCTAGAAGTTGCTGCTAAAAACAGTTATGTTAGTGATACCTAGGAAAGTTTTTTT TCTTTTAACATGTCATTGTGGTTTACAAATGAAAATTGAGGCCGGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTTGGAGGCCAAG GTGGGCGAATCACAAGGTCAGGAGTTCAAGACCAGTCTGGCCAACATGGTGAAACCCCATCTTTACTAAAAATACAAAAAATTAGCTGGG CGTGGTGGTGGGCGCCTGTAATCTCAGCTACTAGGGAGGCTGAGGAAGGAGAATCGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCA AGATCATGCCACCGCACTCCAGCCTGGGCAACAGTGTGAGACTCCATCTCAAAACAAACAAACAAACAAATGAAACAAATGAAAATTGAA ACTTCACCCATTTATGGCTATTGCCTAAAGAATTTATAAATGCCTGGGTCATTGCAAGCATATTGCTGACATGTCTCTCGGTCTGCGTTA CCCTGGTGGACATCACGACACTCACCTGACAGGCAGCAGCTTCCTTCCAGTAAAAGCAAAGAATCTGAAAGGAATGGAAAAGGCTCCACA CAGTGCCATTTTATAGAAGGAAATGCAACAAGGTCACAGACCAGAAGGACAGCAGCCCAGGCCGGCTGGGCATGGAGGAAGTCCCAAGAT GCTGCTGGGCATGAACAGACCTCCTCATACAGTGTGCCTCTGAAGAAATAATGCAATTGTGTGGGGCCAGAGGAGCCACAAATAGAACAA AGGGAGGAAAGGAAAAATCAATATGCAGTAAAGAGGAGGAAGGGAGCCCGGCGCGATGTCTGAATCTCGCTGGCAAGAAAAGGAAACAGG TGGTCTAAGCAGGCAACCCTTCACCCCACATTGTAATGCTGGGGCATGGACGTGTTCCATAGATCACTCACTGAGAAGTCTTCACAAGAA CACTCCAAGGCAGACACTACTATCCATCTTCCACACACTGGGGGATTGAGAGTCAGAAGGATTATACAGCTTGTTCAAATTATAAATAAA >In-frame_ASH2L_ENST00000250635_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_2553nt CACAGCAACGCGCGCGAGAGAAGAGAGTATTCTCGCGAGAAGTCCAGGGGTGGCCGTGATGGCGGCGGCAGGAGCAGGACCTGGCCAGGA AGCGGGTGCCGGGCCTGGCCCAGGAGCGGTCGCAAATGCAACAGGGGCAGAAGAGGGGGAGATGAAGCCGGTGGCAGCGGGAGCAGCCGC TCCTCCTGGAGAGGGGATCTCTGCTGCTCCGACAGTTGAGCCCAGTTCCGGGGAGGCTGAAGGCGGGGAGGCAAACTTGGTCGATGTAAG CGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAGAAGGTGCTGGGGATACATCAGAGGTGATGGATACTCAGGCGGGCTC CGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTCACGGCTGACACATTTGGCAT AGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAA GCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTT CTCCAAAGATAAGGCTTATGAGAATACAGGCCACTGGGAGAGACTCGCATCTGTGGTTTCTTCAAAAACACAGCAGCCCACAGTGATCTC TCATTCTTCCATTTCTATCACATTCAGTCATTACCCTCCAGCCACACTGGACTCCTTTCTTGTCCTGGAACCTATCAAACTCTTTCCTGT CTCAAGCCTCCGCAGTCCTCTCTGCTTGAACTGTGGCTCCTGCAGAGAAAGCATCAGAATCTCCGGGGAACTGATTGGAAATGCACATTC TCCAGCCCCGCCCAGAACTCCTGAATTAGAAACCCTGGGGTGGGACAAGCAAGCCGTGCTTTCTGGGGCACAGGTGATTCTGGTGTGTGC TGAAGTTTAAGAACCACTGGCCGAGAACATTCTTAGGTCTGCTCTTCTTTTGCCCGGCCCCTCCCTCGCGGAGGAATTCCTTCTTATTCC TCTCTGAAGAGTGGCTGCTGCCAAAAAACGTTTGTGAGATGGCCTGGGTTTTCTTTGTTGATTTATCATTTAGTTTGGAAGAAATCAGAA GTCTCTTTAAGAAGCCAATTTGAAACATTCACCCCATGGGAACAGTTCTGGATGAAGTCAGAAGATCTGGAGGCAGCGCAGTAACACACG TAGGTTTTCTGGCCATATGGACATTTCAGAGAAAACAACGCACAGAGGCCTGGAGCAGGTGAACTGGCTTAAGTAGAGAGAAACTAAGTC ATTTGGGGATATTTAGCACCTAATGTCAAGGCAGAAATGTCTAAGATGTAATTAACAGTTATATTCTAATCTCAATAGTAGCTAAGTACA GACTTAAACATAAGCCTGTATATAACAAAATAACCCCAGGAGAACCAAAGAAAATCTAGAAGTTGCTGCTAAAAACAGTTATGTTAGTGA TACCTAGGAAAGTTTTTTTTCTTTTAACATGTCATTGTGGTTTACAAATGAAAATTGAGGCCGGGCGTGGTGGCTCACGCCTGTAATCCC AGCACTTTTGGAGGCCAAGGTGGGCGAATCACAAGGTCAGGAGTTCAAGACCAGTCTGGCCAACATGGTGAAACCCCATCTTTACTAAAA ATACAAAAAATTAGCTGGGCGTGGTGGTGGGCGCCTGTAATCTCAGCTACTAGGGAGGCTGAGGAAGGAGAATCGCTTGAACCTGGGAGG CGGAGGTTGCAGTGAGCCAAGATCATGCCACCGCACTCCAGCCTGGGCAACAGTGTGAGACTCCATCTCAAAACAAACAAACAAACAAAT GAAACAAATGAAAATTGAAACTTCACCCATTTATGGCTATTGCCTAAAGAATTTATAAATGCCTGGGTCATTGCAAGCATATTGCTGACA TGTCTCTCGGTCTGCGTTACCCTGGTGGACATCACGACACTCACCTGACAGGCAGCAGCTTCCTTCCAGTAAAAGCAAAGAATCTGAAAG GAATGGAAAAGGCTCCACACAGTGCCATTTTATAGAAGGAAATGCAACAAGGTCACAGACCAGAAGGACAGCAGCCCAGGCCGGCTGGGC ATGGAGGAAGTCCCAAGATGCTGCTGGGCATGAACAGACCTCCTCATACAGTGTGCCTCTGAAGAAATAATGCAATTGTGTGGGGCCAGA GGAGCCACAAATAGAACAAAGGGAGGAAAGGAAAAATCAATATGCAGTAAAGAGGAGGAAGGGAGCCCGGCGCGATGTCTGAATCTCGCT GGCAAGAAAAGGAAACAGGTGGTCTAAGCAGGCAACCCTTCACCCCACATTGTAATGCTGGGGCATGGACGTGTTCCATAGATCACTCAC TGAGAAGTCTTCACAAGAACACTCCAAGGCAGACACTACTATCCATCTTCCACACACTGGGGGATTGAGAGTCAGAAGGATTATACAGCT >In-frame_ASH2L_ENST00000545394_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_2350nt GATGGCGGCGGCAGGAGCAGGACCTGGCCAGGAAGCGGGTGCCGGGCCTGGCCCAGGAGCGGTCGCAAATGCAACAGGGGCAGAAGAGGG GGAGATGAAGCCGGTGGCAGCGGGAGCAGCCGCTCCTCCTGGAGAGGGGATCTCTGCTGCTCCGACAGTTGAGCCCAGTTCCGGGGAGGC TGAAGGCGGGGAGGCAAACTTGGTCGATGTAAGCGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAATCCTGTCTACCTT TCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGT GCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGCTTATGAGA ATACAGGCCACTGGGAGAGACTCGCATCTGTGGTTTCTTCAAAAACACAGCAGCCCACAGTGATCTCTCATTCTTCCATTTCTATCACAT TCAGTCATTACCCTCCAGCCACACTGGACTCCTTTCTTGTCCTGGAACCTATCAAACTCTTTCCTGTCTCAAGCCTCCGCAGTCCTCTCT GCTTGAACTGTGGCTCCTGCAGAGAAAGCATCAGAATCTCCGGGGAACTGATTGGAAATGCACATTCTCCAGCCCCGCCCAGAACTCCTG AATTAGAAACCCTGGGGTGGGACAAGCAAGCCGTGCTTTCTGGGGCACAGGTGATTCTGGTGTGTGCTGAAGTTTAAGAACCACTGGCCG AGAACATTCTTAGGTCTGCTCTTCTTTTGCCCGGCCCCTCCCTCGCGGAGGAATTCCTTCTTATTCCTCTCTGAAGAGTGGCTGCTGCCA AAAAACGTTTGTGAGATGGCCTGGGTTTTCTTTGTTGATTTATCATTTAGTTTGGAAGAAATCAGAAGTCTCTTTAAGAAGCCAATTTGA AACATTCACCCCATGGGAACAGTTCTGGATGAAGTCAGAAGATCTGGAGGCAGCGCAGTAACACACGTAGGTTTTCTGGCCATATGGACA TTTCAGAGAAAACAACGCACAGAGGCCTGGAGCAGGTGAACTGGCTTAAGTAGAGAGAAACTAAGTCATTTGGGGATATTTAGCACCTAA TGTCAAGGCAGAAATGTCTAAGATGTAATTAACAGTTATATTCTAATCTCAATAGTAGCTAAGTACAGACTTAAACATAAGCCTGTATAT AACAAAATAACCCCAGGAGAACCAAAGAAAATCTAGAAGTTGCTGCTAAAAACAGTTATGTTAGTGATACCTAGGAAAGTTTTTTTTCTT TTAACATGTCATTGTGGTTTACAAATGAAAATTGAGGCCGGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTTGGAGGCCAAGGTGG GCGAATCACAAGGTCAGGAGTTCAAGACCAGTCTGGCCAACATGGTGAAACCCCATCTTTACTAAAAATACAAAAAATTAGCTGGGCGTG GTGGTGGGCGCCTGTAATCTCAGCTACTAGGGAGGCTGAGGAAGGAGAATCGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGAT CATGCCACCGCACTCCAGCCTGGGCAACAGTGTGAGACTCCATCTCAAAACAAACAAACAAACAAATGAAACAAATGAAAATTGAAACTT CACCCATTTATGGCTATTGCCTAAAGAATTTATAAATGCCTGGGTCATTGCAAGCATATTGCTGACATGTCTCTCGGTCTGCGTTACCCT GGTGGACATCACGACACTCACCTGACAGGCAGCAGCTTCCTTCCAGTAAAAGCAAAGAATCTGAAAGGAATGGAAAAGGCTCCACACAGT GCCATTTTATAGAAGGAAATGCAACAAGGTCACAGACCAGAAGGACAGCAGCCCAGGCCGGCTGGGCATGGAGGAAGTCCCAAGATGCTG CTGGGCATGAACAGACCTCCTCATACAGTGTGCCTCTGAAGAAATAATGCAATTGTGTGGGGCCAGAGGAGCCACAAATAGAACAAAGGG AGGAAAGGAAAAATCAATATGCAGTAAAGAGGAGGAAGGGAGCCCGGCGCGATGTCTGAATCTCGCTGGCAAGAAAAGGAAACAGGTGGT CTAAGCAGGCAACCCTTCACCCCACATTGTAATGCTGGGGCATGGACGTGTTCCATAGATCACTCACTGAGAAGTCTTCACAAGAACACT CCAAGGCAGACACTACTATCCATCTTCCACACACTGGGGGATTGAGAGTCAGAAGGATTATACAGCTTGTTCAAATTATAAATAAAAGCC >In-frame_ASH2L_ENST00000428278_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_2654nt ATCCCGCGGCTCCTGGAGCCCTGCCGCCCGCCCCCTGCGAACCCAGGCCCCGCCGCCAATGGCTCGCCCTGCCTCTGCGCCGCTTGGCCC GTCCCCTCTCAAGCATATCTCGGATAACGCCCCTTCCGCACCTTTCACGGGCGGTGGGAGCTGAGGCTCCTGTCGTTATCTCTGATCCTT GCACCCTGGCAGGAAGCTGGTAGCTCACACTTTAACGGGAGGCCTTCACATATTCCAGAAAAGAAACCACTTTGCAGTGCCAGACTGGAA GAAGTAACGGTCACTCTGAAAACAGGGTGGGAGAGCTGCCTCTCTTTGAACCTCTCCCAGGACCAACTCTAACCCAGGGAGGCAAACTTG GTCGATGTAAGCGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAGAAGGTGCTGGGGATACATCAGAGGTGATGGATACT CAGGCGGGCTCCGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCAATGTGGGATTTGTACAAAATGGTTCACGGCTGAC ACATTTGGCATAGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCATTGCAACGTCTGCCATCACAGTGGGAATACCTAT TTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCTGACATGGCAGTCCCGAACACAGGATGAACATCCG AAGACAATGTTCTCCAAAGATAAGGCTTATGAGAATACAGGCCACTGGGAGAGACTCGCATCTGTGGTTTCTTCAAAAACACAGCAGCCC ACAGTGATCTCTCATTCTTCCATTTCTATCACATTCAGTCATTACCCTCCAGCCACACTGGACTCCTTTCTTGTCCTGGAACCTATCAAA CTCTTTCCTGTCTCAAGCCTCCGCAGTCCTCTCTGCTTGAACTGTGGCTCCTGCAGAGAAAGCATCAGAATCTCCGGGGAACTGATTGGA AATGCACATTCTCCAGCCCCGCCCAGAACTCCTGAATTAGAAACCCTGGGGTGGGACAAGCAAGCCGTGCTTTCTGGGGCACAGGTGATT CTGGTGTGTGCTGAAGTTTAAGAACCACTGGCCGAGAACATTCTTAGGTCTGCTCTTCTTTTGCCCGGCCCCTCCCTCGCGGAGGAATTC CTTCTTATTCCTCTCTGAAGAGTGGCTGCTGCCAAAAAACGTTTGTGAGATGGCCTGGGTTTTCTTTGTTGATTTATCATTTAGTTTGGA AGAAATCAGAAGTCTCTTTAAGAAGCCAATTTGAAACATTCACCCCATGGGAACAGTTCTGGATGAAGTCAGAAGATCTGGAGGCAGCGC AGTAACACACGTAGGTTTTCTGGCCATATGGACATTTCAGAGAAAACAACGCACAGAGGCCTGGAGCAGGTGAACTGGCTTAAGTAGAGA GAAACTAAGTCATTTGGGGATATTTAGCACCTAATGTCAAGGCAGAAATGTCTAAGATGTAATTAACAGTTATATTCTAATCTCAATAGT AGCTAAGTACAGACTTAAACATAAGCCTGTATATAACAAAATAACCCCAGGAGAACCAAAGAAAATCTAGAAGTTGCTGCTAAAAACAGT TATGTTAGTGATACCTAGGAAAGTTTTTTTTCTTTTAACATGTCATTGTGGTTTACAAATGAAAATTGAGGCCGGGCGTGGTGGCTCACG CCTGTAATCCCAGCACTTTTGGAGGCCAAGGTGGGCGAATCACAAGGTCAGGAGTTCAAGACCAGTCTGGCCAACATGGTGAAACCCCAT CTTTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGGTGGGCGCCTGTAATCTCAGCTACTAGGGAGGCTGAGGAAGGAGAATCGCTTG AACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGATCATGCCACCGCACTCCAGCCTGGGCAACAGTGTGAGACTCCATCTCAAAACAAACA AACAAACAAATGAAACAAATGAAAATTGAAACTTCACCCATTTATGGCTATTGCCTAAAGAATTTATAAATGCCTGGGTCATTGCAAGCA TATTGCTGACATGTCTCTCGGTCTGCGTTACCCTGGTGGACATCACGACACTCACCTGACAGGCAGCAGCTTCCTTCCAGTAAAAGCAAA GAATCTGAAAGGAATGGAAAAGGCTCCACACAGTGCCATTTTATAGAAGGAAATGCAACAAGGTCACAGACCAGAAGGACAGCAGCCCAG GCCGGCTGGGCATGGAGGAAGTCCCAAGATGCTGCTGGGCATGAACAGACCTCCTCATACAGTGTGCCTCTGAAGAAATAATGCAATTGT GTGGGGCCAGAGGAGCCACAAATAGAACAAAGGGAGGAAAGGAAAAATCAATATGCAGTAAAGAGGAGGAAGGGAGCCCGGCGCGATGTC TGAATCTCGCTGGCAAGAAAAGGAAACAGGTGGTCTAAGCAGGCAACCCTTCACCCCACATTGTAATGCTGGGGCATGGACGTGTTCCAT AGATCACTCACTGAGAAGTCTTCACAAGAACACTCCAAGGCAGACACTACTATCCATCTTCCACACACTGGGGGATTGAGAGTCAGAAGG >In-frame_ASH2L_ENST00000521652_chr8_37968351_+_C8orf86_ENST00000358138_chr8_38374030_-_2508nt GGAGCTGAGGCTCCTGTCGTTATCTCTGATCCTTGCACCCTGGCAGGAAGCTGGTAGCTCACACTTTAACGGGAGGCCTTCACATATTCC AGAAAAGAAACCACTTTGCAGTGCCAGACTGGAAGAAGTAACGGTCACTCTGAAAACAGGGTGGGAGAGCTGCCTCTCTTTGAACCTCTC CCAGGACCAACTCTAACCCAGGGAGGCAAACTTGGTCGATGTAAGCGGTGGCTTGGAGACAGAATCATCTAATGGAAAAGATACACTAGA AGGTGCTGGGGATACATCAGAGGTGATGGATACTCAGGCGGGCTCCGTGGATGAAGAGAATGGCCGACAGTTGGGTGAGGTAGAGCTGCA ATGTGGGATTTGTACAAAATGGTTCACGGCTGACACATTTGGCATAGATACCTCATCCTGTCTACCTTTCATGACCAACTACAGTTTTCA TTGCAACGTCTGCCATCACAGTGGGAATACCTATTTCCTCCGGAAGCAAGCAAACTTGAAGGAAATGTGCCTTAGTGCTTTGGCCAACCT GACATGGCAGTCCCGAACACAGGATGAACATCCGAAGACAATGTTCTCCAAAGATAAGGCTTATGAGAATACAGGCCACTGGGAGAGACT CGCATCTGTGGTTTCTTCAAAAACACAGCAGCCCACAGTGATCTCTCATTCTTCCATTTCTATCACATTCAGTCATTACCCTCCAGCCAC ACTGGACTCCTTTCTTGTCCTGGAACCTATCAAACTCTTTCCTGTCTCAAGCCTCCGCAGTCCTCTCTGCTTGAACTGTGGCTCCTGCAG AGAAAGCATCAGAATCTCCGGGGAACTGATTGGAAATGCACATTCTCCAGCCCCGCCCAGAACTCCTGAATTAGAAACCCTGGGGTGGGA CAAGCAAGCCGTGCTTTCTGGGGCACAGGTGATTCTGGTGTGTGCTGAAGTTTAAGAACCACTGGCCGAGAACATTCTTAGGTCTGCTCT TCTTTTGCCCGGCCCCTCCCTCGCGGAGGAATTCCTTCTTATTCCTCTCTGAAGAGTGGCTGCTGCCAAAAAACGTTTGTGAGATGGCCT GGGTTTTCTTTGTTGATTTATCATTTAGTTTGGAAGAAATCAGAAGTCTCTTTAAGAAGCCAATTTGAAACATTCACCCCATGGGAACAG TTCTGGATGAAGTCAGAAGATCTGGAGGCAGCGCAGTAACACACGTAGGTTTTCTGGCCATATGGACATTTCAGAGAAAACAACGCACAG AGGCCTGGAGCAGGTGAACTGGCTTAAGTAGAGAGAAACTAAGTCATTTGGGGATATTTAGCACCTAATGTCAAGGCAGAAATGTCTAAG ATGTAATTAACAGTTATATTCTAATCTCAATAGTAGCTAAGTACAGACTTAAACATAAGCCTGTATATAACAAAATAACCCCAGGAGAAC CAAAGAAAATCTAGAAGTTGCTGCTAAAAACAGTTATGTTAGTGATACCTAGGAAAGTTTTTTTTCTTTTAACATGTCATTGTGGTTTAC AAATGAAAATTGAGGCCGGGCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTTGGAGGCCAAGGTGGGCGAATCACAAGGTCAGGAGTT CAAGACCAGTCTGGCCAACATGGTGAAACCCCATCTTTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGGTGGGCGCCTGTAATCTCA GCTACTAGGGAGGCTGAGGAAGGAGAATCGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCCAAGATCATGCCACCGCACTCCAGCCTG GGCAACAGTGTGAGACTCCATCTCAAAACAAACAAACAAACAAATGAAACAAATGAAAATTGAAACTTCACCCATTTATGGCTATTGCCT AAAGAATTTATAAATGCCTGGGTCATTGCAAGCATATTGCTGACATGTCTCTCGGTCTGCGTTACCCTGGTGGACATCACGACACTCACC TGACAGGCAGCAGCTTCCTTCCAGTAAAAGCAAAGAATCTGAAAGGAATGGAAAAGGCTCCACACAGTGCCATTTTATAGAAGGAAATGC AACAAGGTCACAGACCAGAAGGACAGCAGCCCAGGCCGGCTGGGCATGGAGGAAGTCCCAAGATGCTGCTGGGCATGAACAGACCTCCTC ATACAGTGTGCCTCTGAAGAAATAATGCAATTGTGTGGGGCCAGAGGAGCCACAAATAGAACAAAGGGAGGAAAGGAAAAATCAATATGC AGTAAAGAGGAGGAAGGGAGCCCGGCGCGATGTCTGAATCTCGCTGGCAAGAAAAGGAAACAGGTGGTCTAAGCAGGCAACCCTTCACCC CACATTGTAATGCTGGGGCATGGACGTGTTCCATAGATCACTCACTGAGAAGTCTTCACAAGAACACTCCAAGGCAGACACTACTATCCA |
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FusionGenePPI for ASH2L_C8orf86 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| ASH2L | DPY30, KMT2A, ASH2L, MEN1, RBBP5, WDR5, HCFC1, HCFC2, KMT2C, HIST3H3, UNC119, CXXC1, SETD1A, WDR82P1, KDM6A, PHF8, MYB, CHD8, CTNNB1, ZNF335, CCAR2, C11orf30, NCOA6, ZSCAN1, HIST1H3A, SRRM1, PAX7, MEF2D, SETD1B, PAXIP1, KMT2D, USF1, PAGR1, KMT2B, E2F1, E2F4, PRMT1, WDR82, PSMC5, PYGO2, CDC73, ESR1, KDM4B, BARD1, BRCA1, PPP1CC, KDM6B, SMAD9, WWP1, SENP3, PPARG, PKN1, EP300, TP53, MICU2, XPO1, FOXQ1, DNMT3L, CHD7, KMT2E, CCDC69, EPB41L5, FOXA1 | C8orf86 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for ASH2L_C8orf86 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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RelatedDiseases for ASH2L_C8orf86 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2018-Present -The University of Texas Health Science Center at Houston (UTHealth)
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