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Fusion gene ID: 29777 |
FusionGeneSummary for PYGB_CNBD2 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: PYGB_CNBD2 | Fusion gene ID: 29777 | Hgene | Tgene | Gene symbol | PYGB | CNBD2 | Gene ID | 5834 | 140894 |
| Gene name | glycogen phosphorylase B | cyclic nucleotide binding domain containing 2 | |
| Synonyms | GPBB | C20orf152|CNMPD1 | |
| Cytomap | 20p11.21 | 20q11.23 | |
| Type of gene | protein-coding | protein-coding | |
| Description | glycogen phosphorylase, brain formphosphorylase, glycogen; brain | cyclic nucleotide-binding domain-containing protein 2cyclic nucleotide (cNMP) binding domain containing 1 | |
| Modification date | 20180523 | 20180523 | |
| UniProtAcc | P11216 | Q96M20 | |
| Ensembl transtripts involved in fusion gene | ENST00000216962, ENST00000471359, | ENST00000373973, ENST00000349339, ENST00000538900, | |
| Fusion gene scores | * DoF score | 6 X 6 X 4=144 | 9 X 6 X 9=486 |
| # samples | 6 | 11 | |
| ** MAII score | log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(11/486*10)=-2.14345279008112 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: PYGB [Title/Abstract] AND CNBD2 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Functional or gene categories assigned by FusionGDB annotation | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene information from three resources (ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018)) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Data type | Source | Cancer type | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| TCGA | LD | COAD | TCGA-AA-3660-01A | PYGB | chr20 | 25273249 | + | CNBD2 | chr20 | 34575317 | + |
| * LD: Li Ding group's fusion gene list RV: Roel Verhaak group's fusion gene list ChiTaRs fusion database |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000216962 | ENST00000373973 | PYGB | chr20 | 25273249 | + | CNBD2 | chr20 | 34575317 | + |
| In-frame | ENST00000216962 | ENST00000349339 | PYGB | chr20 | 25273249 | + | CNBD2 | chr20 | 34575317 | + |
| In-frame | ENST00000216962 | ENST00000538900 | PYGB | chr20 | 25273249 | + | CNBD2 | chr20 | 34575317 | + |
| intron-3CDS | ENST00000471359 | ENST00000373973 | PYGB | chr20 | 25273249 | + | CNBD2 | chr20 | 34575317 | + |
| intron-3CDS | ENST00000471359 | ENST00000349339 | PYGB | chr20 | 25273249 | + | CNBD2 | chr20 | 34575317 | + |
| intron-3CDS | ENST00000471359 | ENST00000538900 | PYGB | chr20 | 25273249 | + | CNBD2 | chr20 | 34575317 | + |
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FusionProtFeatures for PYGB_CNBD2 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| PYGB | CNBD2 |
| Glycogen phosphorylase that regulates glycogenmobilization (PubMed:27402852). Phosphorylase is an importantallosteric enzyme in carbohydrate metabolism (PubMed:3346228).Enzymes from different sources differ in their regulatorymechanisms and in their natural substrates (PubMed:3346228).However, all known phosphorylases share catalytic and structuralproperties (PubMed:3346228). {ECO:0000269|PubMed:27402852,ECO:0000303|PubMed:3346228}. | Essential for male fertility. Plays an important role inspermatogenesis and regulates sperm motility by controlling thedevelopment of the flagellar bending of sperm.{ECO:0000250|UniProtKB:Q9D5U8}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at . * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | PYGB | chr20:25273249 | chr20:34575317 | ENST00000216962 | + | 17 | 20 | 677_678 | 725 | 844 | Region | Pyridoxal 5'-phosphate |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | CNBD2 | chr20:25273249 | chr20:34575317 | ENST00000349339 | + | 5 | 12 | 116_239 | 238 | 573 | Nucleotide binding | Note=cNMP |
| Tgene | CNBD2 | chr20:25273249 | chr20:34575317 | ENST00000373973 | + | 5 | 12 | 116_239 | 238 | 577 | Nucleotide binding | Note=cNMP |
| Tgene | CNBD2 | chr20:25273249 | chr20:34575317 | ENST00000538900 | + | 5 | 11 | 116_239 | 238 | 424 | Nucleotide binding | Note=cNMP |
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FusionGeneSequence for PYGB_CNBD2 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. (nt: nucleotides, aa: amino acids) |
| * Fusion amino acid sequences. |
| >In-frame_PYGB_ENST00000216962_chr20_25273249_+_CNBD2_ENST00000373973_chr20_34575317_+_1064aa MAKPLTDSEKRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEF YMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEA DDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAVLDR NLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKV DWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGS HAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQ ENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDV VNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVE ALDRKGKMELFASWSDEKLWQLVAMAKIERFSYGQLISKDFGESPFIMFISKGSCEVLRLLDLGASPSYRRWIWQHLELIDGRPLKTHLS EYSPMERFKEFQIKSYPLQDFSSLKLPHLKKAWGLQGTSFSRKIRTSGDTLPKMLGPKIQSRPAQSIKCAMINIKPGELPKEAAVGAYVK VHTVEQGEILGLHQAFLPEGECDTRPLILMSLGNELIRIRKEIFYELIDNDDEMIKKLLKLNIAFPSDEDMCQKFLQQNSWNIFRKDLLQ >In-frame_PYGB_ENST00000216962_chr20_25273249_+_CNBD2_ENST00000349339_chr20_34575317_+_1060aa MAKPLTDSEKRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEF YMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEA DDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAVLDR NLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKV DWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGS HAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQ ENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDV VNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVE ALDRKGKMELFASWSDEKLWQLVAMAKIERFSYGQLISKDFGESPFIMFISKGSCEVLRLLDLGASPSYRRWIWQHLELIDGRPLKTHLS EYSPMERFKEFQIKSYPLQDFSSLKLPHLKKAWGLQGTSFSRKIRTSGDTLPKMLGPKIQSRPAQSIKCAMINIKPGELPKEAAVGAYVK VHTVEQGEILAFLPEGECDTRPLILMSLGNELIRIRKEIFYELIDNDDEMIKKLLKLNIAFPSDEDMCQKFLQQNSWNIFRKDLLQLLVE >In-frame_PYGB_ENST00000216962_chr20_25273249_+_CNBD2_ENST00000538900_chr20_34575317_+_911aa MAKPLTDSEKRKQISVRGLAGLGDVAEVRKSFNRHLHFTLVKDRNVATPRDYFFALAHTVRDHLVGRWIRTQQHYYERDPKRIYYLSLEF YMGRTLQNTMVNLGLQNACDEAIYQLGLDLEELEEIEEDAGLGNGGLGRLAACFLDSMATLGLAAYGYGIRYEFGIFNQKIVNGWQVEEA DDWLRYGNPWEKARPEYMLPVHFYGRVEHTPDGVKWLDTQVVLAMPYDTPVPGYKNNTVNTMRLWSAKAPNDFKLQDFNVGDYIEAVLDR NLAENISRVLYPNDNFFEGKELRLKQEYFVVAATLQDIIRRFKSSKFGCRDPVRTCFETFPDKVAIQLNDTHPALSIPELMRILVDVEKV DWDKAWEITKKTCAYTNHTVLPEALERWPVSMFEKLLPRHLEIIYAINQRHLDHVAALFPGDVDRLRRMSVIEEGDCKRINMAHLCVIGS HAVNGVARIHSEIVKQSVFKDFYELEPEKFQNKTNGITPRRWLLLCNPGLADTIVEKIGEEFLTDLSQLKKLLPLVSDEVFIRDVAKVKQ ENKLKFSAFLEKEYKVKINPSSMFDVHVKRIHEYKRQLLNCLHVVTLYNRIKRDPAKAFVPRTVMIGGKAAPGYHMAKLIIKLVTSIGDV VNHDPVVGDRLKVIFLENYRVSLAEKVIPAADLSQQISTAGTEASGTGNMKFMLNGALTIGTMDGANVEMAEEAGAENLFIFGLRVEDVE ALDRKGKMELFASWSDEKLWQLVAMAKIERFSYGQLISKDFGESPFIMFISKGSCEVLRLLDLGASPSYRRWIWQHLELIDGRPLKTHLS EYSPMERFKEFQIKSYPLQDFSSLKLPHLKKAWGLQGTSFSRKIRTSGDTLPKMLGPKIQSRPAQSIKCAMINIKPGELPKEAAVGAYVK |
| * Fusion transcript sequences (only coding sequence (CDS) region). |
| >In-frame_PYGB_ENST00000216962_chr20_25273249_+_CNBD2_ENST00000373973_chr20_34575317_+_3192nt ATGGCGAAGCCGCTGACGGACAGCGAGAAGCGGAAGCAGATCAGCGTGCGCGGCCTGGCGGGGCTAGGCGACGTGGCCGAGGTGCGGAAG AGCTTCAACCGGCACTTGCACTTCACGCTGGTCAAGGACCGCAATGTGGCCACGCCCCGCGACTACTTCTTCGCGCTGGCGCACACGGTG CGCGACCACCTCGTGGGCCGCTGGATCCGCACGCAGCAGCACTACTACGAGCGCGACCCCAAGCGCATTTATTATCTTTCCCTGGAATTC TACATGGGTCGCACGCTGCAGAACACGATGGTGAACCTGGGCCTTCAGAATGCCTGCGATGAAGCCATCTATCAGTTGGGGTTAGACTTG GAGGAACTCGAGGAGATAGAAGAAGATGCTGGCCTTGGGAATGGAGGCCTGGGGAGGCTGGCAGCGTGTTTCCTTGACTCAATGGCTACC TTGGGCCTGGCAGCATACGGCTATGGAATCCGCTATGAATTTGGGATTTTTAACCAGAAGATTGTCAATGGCTGGCAGGTAGAGGAGGCC GATGACTGGCTGCGCTACGGCAACCCCTGGGAGAAAGCGCGGCCTGAGTATATGCTTCCCGTGCACTTCTACGGACGCGTGGAGCACACC CCCGACGGCGTGAAGTGGCTGGACACACAGGTGGTGCTGGCCATGCCCTACGACACCCCAGTGCCCGGCTACAAGAACAACACCGTCAAC ACCATGCGGCTGTGGTCCGCCAAGGCTCCCAACGACTTCAAGCTGCAGGACTTCAACGTGGGAGACTACATCGAGGCGGTCCTGGACCGG AACTTGGCTGAGAACATCTCCAGGGTCCTGTATCCAAATGATAACTTCTTTGAGGGGAAGGAGCTGCGGCTGAAGCAGGAGTACTTCGTG GTGGCCGCCACGCTCCAGGACATCATCCGCCGCTTCAAGTCGTCCAAGTTCGGCTGCCGGGACCCTGTGAGAACCTGTTTCGAGACGTTC CCAGACAAGGTGGCCATCCAGCTGAACGACACCCACCCCGCCCTCTCCATCCCTGAGCTCATGCGGATCCTGGTGGACGTGGAGAAGGTG GACTGGGACAAGGCCTGGGAAATCACGAAGAAGACCTGTGCATACACCAACCACACTGTGCTGCCTGAGGCCTTGGAGCGCTGGCCCGTG TCCATGTTTGAGAAGCTGCTGCCGCGGCACCTGGAGATAATCTATGCCATCAACCAGCGGCACCTGGACCACGTGGCCGCGCTGTTTCCC GGCGATGTGGACCGCCTGCGCAGGATGTCTGTGATCGAGGAGGGGGACTGCAAGCGGATCAACATGGCCCACCTGTGTGTGATTGGGTCC CATGCTGTCAATGGTGTGGCGAGGATCCACTCGGAGATCGTGAAACAGTCGGTCTTTAAGGATTTTTATGAACTGGAGCCAGAGAAGTTC CAGAATAAGACCAATGGCATCACCCCCCGCCGGTGGCTGCTGCTGTGCAACCCGGGGCTGGCCGATACCATCGTGGAGAAAATTGGGGAG GAGTTCCTGACTGACCTGAGCCAGCTGAAGAAGCTGCTGCCGCTGGTCAGTGACGAGGTGTTCATCAGGGACGTGGCCAAGGTCAAACAG GAGAACAAGCTCAAGTTCTCGGCCTTCCTGGAGAAGGAGTACAAGGTGAAGATCAACCCCTCCTCCATGTTCGATGTGCATGTGAAGAGG ATCCACGAGTACAAGCGGCAGCTGCTCAACTGCCTGCACGTCGTCACCCTGTACAATCGAATCAAGAGAGACCCGGCCAAGGCTTTTGTG CCCAGGACTGTTATGATTGGGGGCAAGGCAGCGCCCGGTTACCACATGGCCAAGCTGATCATCAAGTTGGTCACCTCCATCGGCGACGTC GTCAATCATGACCCAGTTGTGGGTGACAGGTTGAAAGTGATCTTCCTGGAGAACTACCGTGTGTCCTTGGCTGAGAAAGTGATCCCGGCC GCTGATCTGTCGCAGCAGATCTCCACTGCAGGCACCGAGGCCTCAGGCACAGGCAACATGAAGTTCATGCTCAACGGGGCCCTCACCATC GGCACCATGGACGGCGCCAACGTGGAGATGGCCGAGGAGGCCGGGGCCGAGAACCTCTTCATCTTCGGCCTGCGGGTGGAGGATGTCGAG GCCTTGGACCGGAAAGGGAAGATGGAGCTGTTTGCATCATGGTCTGATGAGAAGCTCTGGCAGCTGGTAGCCATGGCGAAGATAGAGAGG TTCTCGTATGGGCAGCTGATCTCAAAAGATTTTGGAGAGTCACCCTTCATCATGTTTATCAGCAAGGGCAGCTGTGAAGTCCTGCGGCTG TTGGACCTTGGGGCCTCCCCTTCCTACCGTAGATGGATCTGGCAGCACCTGGAGCTGATAGATGGCAGACCTCTGAAGACCCACCTGAGT GAATACTCTCCTATGGAAAGATTTAAGGAATTCCAGATCAAATCATATCCTCTGCAAGACTTTAGCTCCTTGAAACTTCCACATCTCAAA AAAGCCTGGGGGCTACAGGGGACAAGCTTCAGCAGGAAGATCAGAACCTCAGGAGACACTCTCCCCAAGATGCTGGGCCCGAAGATCCAA TCCAGGCCTGCTCAGTCGATCAAATGTGCCATGATCAATATCAAGCCTGGTGAGCTCCCCAAGGAGGCTGCAGTGGGGGCCTACGTGAAG GTGCACACTGTGGAGCAGGGAGAAATTTTGGGTCTTCACCAGGCCTTCCTTCCAGAGGGTGAATGCGACACACGACCCTTGATCCTGATG AGCCTGGGAAATGAGTTGATACGGATAAGGAAGGAAATATTTTATGAACTGATTGACAATGATGACGAGATGATAAAAAAGTTGTTAAAG CTCAATATTGCATTCCCCAGTGATGAAGATATGTGCCAGAAGTTCCTCCAGCAGAACAGCTGGAATATCTTTCGGAAGGACCTGTTGCAG CTGCTCGTGGAGCCTTGCCAAAGTCAACTGTTCACTCCAAACCGGCCCAAGAAGAGAGAGATCTACAACCCTAAGTCTGTGGTCCTGGAT TTGTGCAGCATCAACAAGACGACTAAACCTCGTTATCCTATTTTTATGGCACCCCAGAAATACCTCCCCCCATTGAGGATTGTCCAAGCC >In-frame_PYGB_ENST00000216962_chr20_25273249_+_CNBD2_ENST00000349339_chr20_34575317_+_3180nt ATGGCGAAGCCGCTGACGGACAGCGAGAAGCGGAAGCAGATCAGCGTGCGCGGCCTGGCGGGGCTAGGCGACGTGGCCGAGGTGCGGAAG AGCTTCAACCGGCACTTGCACTTCACGCTGGTCAAGGACCGCAATGTGGCCACGCCCCGCGACTACTTCTTCGCGCTGGCGCACACGGTG CGCGACCACCTCGTGGGCCGCTGGATCCGCACGCAGCAGCACTACTACGAGCGCGACCCCAAGCGCATTTATTATCTTTCCCTGGAATTC TACATGGGTCGCACGCTGCAGAACACGATGGTGAACCTGGGCCTTCAGAATGCCTGCGATGAAGCCATCTATCAGTTGGGGTTAGACTTG GAGGAACTCGAGGAGATAGAAGAAGATGCTGGCCTTGGGAATGGAGGCCTGGGGAGGCTGGCAGCGTGTTTCCTTGACTCAATGGCTACC TTGGGCCTGGCAGCATACGGCTATGGAATCCGCTATGAATTTGGGATTTTTAACCAGAAGATTGTCAATGGCTGGCAGGTAGAGGAGGCC GATGACTGGCTGCGCTACGGCAACCCCTGGGAGAAAGCGCGGCCTGAGTATATGCTTCCCGTGCACTTCTACGGACGCGTGGAGCACACC CCCGACGGCGTGAAGTGGCTGGACACACAGGTGGTGCTGGCCATGCCCTACGACACCCCAGTGCCCGGCTACAAGAACAACACCGTCAAC ACCATGCGGCTGTGGTCCGCCAAGGCTCCCAACGACTTCAAGCTGCAGGACTTCAACGTGGGAGACTACATCGAGGCGGTCCTGGACCGG AACTTGGCTGAGAACATCTCCAGGGTCCTGTATCCAAATGATAACTTCTTTGAGGGGAAGGAGCTGCGGCTGAAGCAGGAGTACTTCGTG GTGGCCGCCACGCTCCAGGACATCATCCGCCGCTTCAAGTCGTCCAAGTTCGGCTGCCGGGACCCTGTGAGAACCTGTTTCGAGACGTTC CCAGACAAGGTGGCCATCCAGCTGAACGACACCCACCCCGCCCTCTCCATCCCTGAGCTCATGCGGATCCTGGTGGACGTGGAGAAGGTG GACTGGGACAAGGCCTGGGAAATCACGAAGAAGACCTGTGCATACACCAACCACACTGTGCTGCCTGAGGCCTTGGAGCGCTGGCCCGTG TCCATGTTTGAGAAGCTGCTGCCGCGGCACCTGGAGATAATCTATGCCATCAACCAGCGGCACCTGGACCACGTGGCCGCGCTGTTTCCC GGCGATGTGGACCGCCTGCGCAGGATGTCTGTGATCGAGGAGGGGGACTGCAAGCGGATCAACATGGCCCACCTGTGTGTGATTGGGTCC CATGCTGTCAATGGTGTGGCGAGGATCCACTCGGAGATCGTGAAACAGTCGGTCTTTAAGGATTTTTATGAACTGGAGCCAGAGAAGTTC CAGAATAAGACCAATGGCATCACCCCCCGCCGGTGGCTGCTGCTGTGCAACCCGGGGCTGGCCGATACCATCGTGGAGAAAATTGGGGAG GAGTTCCTGACTGACCTGAGCCAGCTGAAGAAGCTGCTGCCGCTGGTCAGTGACGAGGTGTTCATCAGGGACGTGGCCAAGGTCAAACAG GAGAACAAGCTCAAGTTCTCGGCCTTCCTGGAGAAGGAGTACAAGGTGAAGATCAACCCCTCCTCCATGTTCGATGTGCATGTGAAGAGG ATCCACGAGTACAAGCGGCAGCTGCTCAACTGCCTGCACGTCGTCACCCTGTACAATCGAATCAAGAGAGACCCGGCCAAGGCTTTTGTG CCCAGGACTGTTATGATTGGGGGCAAGGCAGCGCCCGGTTACCACATGGCCAAGCTGATCATCAAGTTGGTCACCTCCATCGGCGACGTC GTCAATCATGACCCAGTTGTGGGTGACAGGTTGAAAGTGATCTTCCTGGAGAACTACCGTGTGTCCTTGGCTGAGAAAGTGATCCCGGCC GCTGATCTGTCGCAGCAGATCTCCACTGCAGGCACCGAGGCCTCAGGCACAGGCAACATGAAGTTCATGCTCAACGGGGCCCTCACCATC GGCACCATGGACGGCGCCAACGTGGAGATGGCCGAGGAGGCCGGGGCCGAGAACCTCTTCATCTTCGGCCTGCGGGTGGAGGATGTCGAG GCCTTGGACCGGAAAGGGAAGATGGAGCTGTTTGCATCATGGTCTGATGAGAAGCTCTGGCAGCTGGTAGCCATGGCGAAGATAGAGAGG TTCTCGTATGGGCAGCTGATCTCAAAAGATTTTGGAGAGTCACCCTTCATCATGTTTATCAGCAAGGGCAGCTGTGAAGTCCTGCGGCTG TTGGACCTTGGGGCCTCCCCTTCCTACCGTAGATGGATCTGGCAGCACCTGGAGCTGATAGATGGCAGACCTCTGAAGACCCACCTGAGT GAATACTCTCCTATGGAAAGATTTAAGGAATTCCAGATCAAATCATATCCTCTGCAAGACTTTAGCTCCTTGAAACTTCCACATCTCAAA AAAGCCTGGGGGCTACAGGGGACAAGCTTCAGCAGGAAGATCAGAACCTCAGGAGACACTCTCCCCAAGATGCTGGGCCCGAAGATCCAA TCCAGGCCTGCTCAGTCGATCAAATGTGCCATGATCAATATCAAGCCTGGTGAGCTCCCCAAGGAGGCTGCAGTGGGGGCCTACGTGAAG GTGCACACTGTGGAGCAGGGAGAAATTTTGGCCTTCCTTCCAGAGGGTGAATGCGACACACGACCCTTGATCCTGATGAGCCTGGGAAAT GAGTTGATACGGATAAGGAAGGAAATATTTTATGAACTGATTGACAATGATGACGAGATGATAAAAAAGTTGTTAAAGCTCAATATTGCA TTCCCCAGTGATGAAGATATGTGCCAGAAGTTCCTCCAGCAGAACAGCTGGAATATCTTTCGGAAGGACCTGTTGCAGCTGCTCGTGGAG CCTTGCCAAAGTCAACTGTTCACTCCAAACCGGCCCAAGAAGAGAGAGATCTACAACCCTAAGTCTGTGGTCCTGGATTTGTGCAGCATC AACAAGACGACTAAACCTCGTTATCCTATTTTTATGGCACCCCAGAAATACCTCCCCCCATTGAGGATTGTCCAAGCCATCAAAGCACCT >In-frame_PYGB_ENST00000216962_chr20_25273249_+_CNBD2_ENST00000538900_chr20_34575317_+_2733nt ATGGCGAAGCCGCTGACGGACAGCGAGAAGCGGAAGCAGATCAGCGTGCGCGGCCTGGCGGGGCTAGGCGACGTGGCCGAGGTGCGGAAG AGCTTCAACCGGCACTTGCACTTCACGCTGGTCAAGGACCGCAATGTGGCCACGCCCCGCGACTACTTCTTCGCGCTGGCGCACACGGTG CGCGACCACCTCGTGGGCCGCTGGATCCGCACGCAGCAGCACTACTACGAGCGCGACCCCAAGCGCATTTATTATCTTTCCCTGGAATTC TACATGGGTCGCACGCTGCAGAACACGATGGTGAACCTGGGCCTTCAGAATGCCTGCGATGAAGCCATCTATCAGTTGGGGTTAGACTTG GAGGAACTCGAGGAGATAGAAGAAGATGCTGGCCTTGGGAATGGAGGCCTGGGGAGGCTGGCAGCGTGTTTCCTTGACTCAATGGCTACC TTGGGCCTGGCAGCATACGGCTATGGAATCCGCTATGAATTTGGGATTTTTAACCAGAAGATTGTCAATGGCTGGCAGGTAGAGGAGGCC GATGACTGGCTGCGCTACGGCAACCCCTGGGAGAAAGCGCGGCCTGAGTATATGCTTCCCGTGCACTTCTACGGACGCGTGGAGCACACC CCCGACGGCGTGAAGTGGCTGGACACACAGGTGGTGCTGGCCATGCCCTACGACACCCCAGTGCCCGGCTACAAGAACAACACCGTCAAC ACCATGCGGCTGTGGTCCGCCAAGGCTCCCAACGACTTCAAGCTGCAGGACTTCAACGTGGGAGACTACATCGAGGCGGTCCTGGACCGG AACTTGGCTGAGAACATCTCCAGGGTCCTGTATCCAAATGATAACTTCTTTGAGGGGAAGGAGCTGCGGCTGAAGCAGGAGTACTTCGTG GTGGCCGCCACGCTCCAGGACATCATCCGCCGCTTCAAGTCGTCCAAGTTCGGCTGCCGGGACCCTGTGAGAACCTGTTTCGAGACGTTC CCAGACAAGGTGGCCATCCAGCTGAACGACACCCACCCCGCCCTCTCCATCCCTGAGCTCATGCGGATCCTGGTGGACGTGGAGAAGGTG GACTGGGACAAGGCCTGGGAAATCACGAAGAAGACCTGTGCATACACCAACCACACTGTGCTGCCTGAGGCCTTGGAGCGCTGGCCCGTG TCCATGTTTGAGAAGCTGCTGCCGCGGCACCTGGAGATAATCTATGCCATCAACCAGCGGCACCTGGACCACGTGGCCGCGCTGTTTCCC GGCGATGTGGACCGCCTGCGCAGGATGTCTGTGATCGAGGAGGGGGACTGCAAGCGGATCAACATGGCCCACCTGTGTGTGATTGGGTCC CATGCTGTCAATGGTGTGGCGAGGATCCACTCGGAGATCGTGAAACAGTCGGTCTTTAAGGATTTTTATGAACTGGAGCCAGAGAAGTTC CAGAATAAGACCAATGGCATCACCCCCCGCCGGTGGCTGCTGCTGTGCAACCCGGGGCTGGCCGATACCATCGTGGAGAAAATTGGGGAG GAGTTCCTGACTGACCTGAGCCAGCTGAAGAAGCTGCTGCCGCTGGTCAGTGACGAGGTGTTCATCAGGGACGTGGCCAAGGTCAAACAG GAGAACAAGCTCAAGTTCTCGGCCTTCCTGGAGAAGGAGTACAAGGTGAAGATCAACCCCTCCTCCATGTTCGATGTGCATGTGAAGAGG ATCCACGAGTACAAGCGGCAGCTGCTCAACTGCCTGCACGTCGTCACCCTGTACAATCGAATCAAGAGAGACCCGGCCAAGGCTTTTGTG CCCAGGACTGTTATGATTGGGGGCAAGGCAGCGCCCGGTTACCACATGGCCAAGCTGATCATCAAGTTGGTCACCTCCATCGGCGACGTC GTCAATCATGACCCAGTTGTGGGTGACAGGTTGAAAGTGATCTTCCTGGAGAACTACCGTGTGTCCTTGGCTGAGAAAGTGATCCCGGCC GCTGATCTGTCGCAGCAGATCTCCACTGCAGGCACCGAGGCCTCAGGCACAGGCAACATGAAGTTCATGCTCAACGGGGCCCTCACCATC GGCACCATGGACGGCGCCAACGTGGAGATGGCCGAGGAGGCCGGGGCCGAGAACCTCTTCATCTTCGGCCTGCGGGTGGAGGATGTCGAG GCCTTGGACCGGAAAGGGAAGATGGAGCTGTTTGCATCATGGTCTGATGAGAAGCTCTGGCAGCTGGTAGCCATGGCGAAGATAGAGAGG TTCTCGTATGGGCAGCTGATCTCAAAAGATTTTGGAGAGTCACCCTTCATCATGTTTATCAGCAAGGGCAGCTGTGAAGTCCTGCGGCTG TTGGACCTTGGGGCCTCCCCTTCCTACCGTAGATGGATCTGGCAGCACCTGGAGCTGATAGATGGCAGACCTCTGAAGACCCACCTGAGT GAATACTCTCCTATGGAAAGATTTAAGGAATTCCAGATCAAATCATATCCTCTGCAAGACTTTAGCTCCTTGAAACTTCCACATCTCAAA AAAGCCTGGGGGCTACAGGGGACAAGCTTCAGCAGGAAGATCAGAACCTCAGGAGACACTCTCCCCAAGATGCTGGGCCCGAAGATCCAA TCCAGGCCTGCTCAGTCGATCAAATGTGCCATGATCAATATCAAGCCTGGTGAGCTCCCCAAGGAGGCTGCAGTGGGGGCCTACGTGAAG |
| * Fusion transcript sequences (Full-length transcript). |
| >In-frame_PYGB_ENST00000216962_chr20_25273249_+_CNBD2_ENST00000373973_chr20_34575317_+_3354nt CGCAGTGCCGGGCGCCAGAGCAGCGGCGCCAGAGCAGCTGCACCATCCCGGCGTTCGCGTGTGCCGCCGCTTTCCTCCTCCATCTCTTTT CCTCCGCCTCCGCCGGCGCGATGGCGAAGCCGCTGACGGACAGCGAGAAGCGGAAGCAGATCAGCGTGCGCGGCCTGGCGGGGCTAGGCG ACGTGGCCGAGGTGCGGAAGAGCTTCAACCGGCACTTGCACTTCACGCTGGTCAAGGACCGCAATGTGGCCACGCCCCGCGACTACTTCT TCGCGCTGGCGCACACGGTGCGCGACCACCTCGTGGGCCGCTGGATCCGCACGCAGCAGCACTACTACGAGCGCGACCCCAAGCGCATTT ATTATCTTTCCCTGGAATTCTACATGGGTCGCACGCTGCAGAACACGATGGTGAACCTGGGCCTTCAGAATGCCTGCGATGAAGCCATCT ATCAGTTGGGGTTAGACTTGGAGGAACTCGAGGAGATAGAAGAAGATGCTGGCCTTGGGAATGGAGGCCTGGGGAGGCTGGCAGCGTGTT TCCTTGACTCAATGGCTACCTTGGGCCTGGCAGCATACGGCTATGGAATCCGCTATGAATTTGGGATTTTTAACCAGAAGATTGTCAATG GCTGGCAGGTAGAGGAGGCCGATGACTGGCTGCGCTACGGCAACCCCTGGGAGAAAGCGCGGCCTGAGTATATGCTTCCCGTGCACTTCT ACGGACGCGTGGAGCACACCCCCGACGGCGTGAAGTGGCTGGACACACAGGTGGTGCTGGCCATGCCCTACGACACCCCAGTGCCCGGCT ACAAGAACAACACCGTCAACACCATGCGGCTGTGGTCCGCCAAGGCTCCCAACGACTTCAAGCTGCAGGACTTCAACGTGGGAGACTACA TCGAGGCGGTCCTGGACCGGAACTTGGCTGAGAACATCTCCAGGGTCCTGTATCCAAATGATAACTTCTTTGAGGGGAAGGAGCTGCGGC TGAAGCAGGAGTACTTCGTGGTGGCCGCCACGCTCCAGGACATCATCCGCCGCTTCAAGTCGTCCAAGTTCGGCTGCCGGGACCCTGTGA GAACCTGTTTCGAGACGTTCCCAGACAAGGTGGCCATCCAGCTGAACGACACCCACCCCGCCCTCTCCATCCCTGAGCTCATGCGGATCC TGGTGGACGTGGAGAAGGTGGACTGGGACAAGGCCTGGGAAATCACGAAGAAGACCTGTGCATACACCAACCACACTGTGCTGCCTGAGG CCTTGGAGCGCTGGCCCGTGTCCATGTTTGAGAAGCTGCTGCCGCGGCACCTGGAGATAATCTATGCCATCAACCAGCGGCACCTGGACC ACGTGGCCGCGCTGTTTCCCGGCGATGTGGACCGCCTGCGCAGGATGTCTGTGATCGAGGAGGGGGACTGCAAGCGGATCAACATGGCCC ACCTGTGTGTGATTGGGTCCCATGCTGTCAATGGTGTGGCGAGGATCCACTCGGAGATCGTGAAACAGTCGGTCTTTAAGGATTTTTATG AACTGGAGCCAGAGAAGTTCCAGAATAAGACCAATGGCATCACCCCCCGCCGGTGGCTGCTGCTGTGCAACCCGGGGCTGGCCGATACCA TCGTGGAGAAAATTGGGGAGGAGTTCCTGACTGACCTGAGCCAGCTGAAGAAGCTGCTGCCGCTGGTCAGTGACGAGGTGTTCATCAGGG ACGTGGCCAAGGTCAAACAGGAGAACAAGCTCAAGTTCTCGGCCTTCCTGGAGAAGGAGTACAAGGTGAAGATCAACCCCTCCTCCATGT TCGATGTGCATGTGAAGAGGATCCACGAGTACAAGCGGCAGCTGCTCAACTGCCTGCACGTCGTCACCCTGTACAATCGAATCAAGAGAG ACCCGGCCAAGGCTTTTGTGCCCAGGACTGTTATGATTGGGGGCAAGGCAGCGCCCGGTTACCACATGGCCAAGCTGATCATCAAGTTGG TCACCTCCATCGGCGACGTCGTCAATCATGACCCAGTTGTGGGTGACAGGTTGAAAGTGATCTTCCTGGAGAACTACCGTGTGTCCTTGG CTGAGAAAGTGATCCCGGCCGCTGATCTGTCGCAGCAGATCTCCACTGCAGGCACCGAGGCCTCAGGCACAGGCAACATGAAGTTCATGC TCAACGGGGCCCTCACCATCGGCACCATGGACGGCGCCAACGTGGAGATGGCCGAGGAGGCCGGGGCCGAGAACCTCTTCATCTTCGGCC TGCGGGTGGAGGATGTCGAGGCCTTGGACCGGAAAGGGAAGATGGAGCTGTTTGCATCATGGTCTGATGAGAAGCTCTGGCAGCTGGTAG CCATGGCGAAGATAGAGAGGTTCTCGTATGGGCAGCTGATCTCAAAAGATTTTGGAGAGTCACCCTTCATCATGTTTATCAGCAAGGGCA GCTGTGAAGTCCTGCGGCTGTTGGACCTTGGGGCCTCCCCTTCCTACCGTAGATGGATCTGGCAGCACCTGGAGCTGATAGATGGCAGAC CTCTGAAGACCCACCTGAGTGAATACTCTCCTATGGAAAGATTTAAGGAATTCCAGATCAAATCATATCCTCTGCAAGACTTTAGCTCCT TGAAACTTCCACATCTCAAAAAAGCCTGGGGGCTACAGGGGACAAGCTTCAGCAGGAAGATCAGAACCTCAGGAGACACTCTCCCCAAGA TGCTGGGCCCGAAGATCCAATCCAGGCCTGCTCAGTCGATCAAATGTGCCATGATCAATATCAAGCCTGGTGAGCTCCCCAAGGAGGCTG CAGTGGGGGCCTACGTGAAGGTGCACACTGTGGAGCAGGGAGAAATTTTGGGTCTTCACCAGGCCTTCCTTCCAGAGGGTGAATGCGACA CACGACCCTTGATCCTGATGAGCCTGGGAAATGAGTTGATACGGATAAGGAAGGAAATATTTTATGAACTGATTGACAATGATGACGAGA TGATAAAAAAGTTGTTAAAGCTCAATATTGCATTCCCCAGTGATGAAGATATGTGCCAGAAGTTCCTCCAGCAGAACAGCTGGAATATCT TTCGGAAGGACCTGTTGCAGCTGCTCGTGGAGCCTTGCCAAAGTCAACTGTTCACTCCAAACCGGCCCAAGAAGAGAGAGATCTACAACC CTAAGTCTGTGGTCCTGGATTTGTGCAGCATCAACAAGACGACTAAACCTCGTTATCCTATTTTTATGGCACCCCAGAAATACCTCCCCC CATTGAGGATTGTCCAAGCCATCAAAGCACCTCGGTACAAAATCCGAGAACTCTTGGCTTAGTGTAAGAGCACAGGGGTCCTTATTTAGG >In-frame_PYGB_ENST00000216962_chr20_25273249_+_CNBD2_ENST00000349339_chr20_34575317_+_3342nt CGCAGTGCCGGGCGCCAGAGCAGCGGCGCCAGAGCAGCTGCACCATCCCGGCGTTCGCGTGTGCCGCCGCTTTCCTCCTCCATCTCTTTT CCTCCGCCTCCGCCGGCGCGATGGCGAAGCCGCTGACGGACAGCGAGAAGCGGAAGCAGATCAGCGTGCGCGGCCTGGCGGGGCTAGGCG ACGTGGCCGAGGTGCGGAAGAGCTTCAACCGGCACTTGCACTTCACGCTGGTCAAGGACCGCAATGTGGCCACGCCCCGCGACTACTTCT TCGCGCTGGCGCACACGGTGCGCGACCACCTCGTGGGCCGCTGGATCCGCACGCAGCAGCACTACTACGAGCGCGACCCCAAGCGCATTT ATTATCTTTCCCTGGAATTCTACATGGGTCGCACGCTGCAGAACACGATGGTGAACCTGGGCCTTCAGAATGCCTGCGATGAAGCCATCT ATCAGTTGGGGTTAGACTTGGAGGAACTCGAGGAGATAGAAGAAGATGCTGGCCTTGGGAATGGAGGCCTGGGGAGGCTGGCAGCGTGTT TCCTTGACTCAATGGCTACCTTGGGCCTGGCAGCATACGGCTATGGAATCCGCTATGAATTTGGGATTTTTAACCAGAAGATTGTCAATG GCTGGCAGGTAGAGGAGGCCGATGACTGGCTGCGCTACGGCAACCCCTGGGAGAAAGCGCGGCCTGAGTATATGCTTCCCGTGCACTTCT ACGGACGCGTGGAGCACACCCCCGACGGCGTGAAGTGGCTGGACACACAGGTGGTGCTGGCCATGCCCTACGACACCCCAGTGCCCGGCT ACAAGAACAACACCGTCAACACCATGCGGCTGTGGTCCGCCAAGGCTCCCAACGACTTCAAGCTGCAGGACTTCAACGTGGGAGACTACA TCGAGGCGGTCCTGGACCGGAACTTGGCTGAGAACATCTCCAGGGTCCTGTATCCAAATGATAACTTCTTTGAGGGGAAGGAGCTGCGGC TGAAGCAGGAGTACTTCGTGGTGGCCGCCACGCTCCAGGACATCATCCGCCGCTTCAAGTCGTCCAAGTTCGGCTGCCGGGACCCTGTGA GAACCTGTTTCGAGACGTTCCCAGACAAGGTGGCCATCCAGCTGAACGACACCCACCCCGCCCTCTCCATCCCTGAGCTCATGCGGATCC TGGTGGACGTGGAGAAGGTGGACTGGGACAAGGCCTGGGAAATCACGAAGAAGACCTGTGCATACACCAACCACACTGTGCTGCCTGAGG CCTTGGAGCGCTGGCCCGTGTCCATGTTTGAGAAGCTGCTGCCGCGGCACCTGGAGATAATCTATGCCATCAACCAGCGGCACCTGGACC ACGTGGCCGCGCTGTTTCCCGGCGATGTGGACCGCCTGCGCAGGATGTCTGTGATCGAGGAGGGGGACTGCAAGCGGATCAACATGGCCC ACCTGTGTGTGATTGGGTCCCATGCTGTCAATGGTGTGGCGAGGATCCACTCGGAGATCGTGAAACAGTCGGTCTTTAAGGATTTTTATG AACTGGAGCCAGAGAAGTTCCAGAATAAGACCAATGGCATCACCCCCCGCCGGTGGCTGCTGCTGTGCAACCCGGGGCTGGCCGATACCA TCGTGGAGAAAATTGGGGAGGAGTTCCTGACTGACCTGAGCCAGCTGAAGAAGCTGCTGCCGCTGGTCAGTGACGAGGTGTTCATCAGGG ACGTGGCCAAGGTCAAACAGGAGAACAAGCTCAAGTTCTCGGCCTTCCTGGAGAAGGAGTACAAGGTGAAGATCAACCCCTCCTCCATGT TCGATGTGCATGTGAAGAGGATCCACGAGTACAAGCGGCAGCTGCTCAACTGCCTGCACGTCGTCACCCTGTACAATCGAATCAAGAGAG ACCCGGCCAAGGCTTTTGTGCCCAGGACTGTTATGATTGGGGGCAAGGCAGCGCCCGGTTACCACATGGCCAAGCTGATCATCAAGTTGG TCACCTCCATCGGCGACGTCGTCAATCATGACCCAGTTGTGGGTGACAGGTTGAAAGTGATCTTCCTGGAGAACTACCGTGTGTCCTTGG CTGAGAAAGTGATCCCGGCCGCTGATCTGTCGCAGCAGATCTCCACTGCAGGCACCGAGGCCTCAGGCACAGGCAACATGAAGTTCATGC TCAACGGGGCCCTCACCATCGGCACCATGGACGGCGCCAACGTGGAGATGGCCGAGGAGGCCGGGGCCGAGAACCTCTTCATCTTCGGCC TGCGGGTGGAGGATGTCGAGGCCTTGGACCGGAAAGGGAAGATGGAGCTGTTTGCATCATGGTCTGATGAGAAGCTCTGGCAGCTGGTAG CCATGGCGAAGATAGAGAGGTTCTCGTATGGGCAGCTGATCTCAAAAGATTTTGGAGAGTCACCCTTCATCATGTTTATCAGCAAGGGCA GCTGTGAAGTCCTGCGGCTGTTGGACCTTGGGGCCTCCCCTTCCTACCGTAGATGGATCTGGCAGCACCTGGAGCTGATAGATGGCAGAC CTCTGAAGACCCACCTGAGTGAATACTCTCCTATGGAAAGATTTAAGGAATTCCAGATCAAATCATATCCTCTGCAAGACTTTAGCTCCT TGAAACTTCCACATCTCAAAAAAGCCTGGGGGCTACAGGGGACAAGCTTCAGCAGGAAGATCAGAACCTCAGGAGACACTCTCCCCAAGA TGCTGGGCCCGAAGATCCAATCCAGGCCTGCTCAGTCGATCAAATGTGCCATGATCAATATCAAGCCTGGTGAGCTCCCCAAGGAGGCTG CAGTGGGGGCCTACGTGAAGGTGCACACTGTGGAGCAGGGAGAAATTTTGGCCTTCCTTCCAGAGGGTGAATGCGACACACGACCCTTGA TCCTGATGAGCCTGGGAAATGAGTTGATACGGATAAGGAAGGAAATATTTTATGAACTGATTGACAATGATGACGAGATGATAAAAAAGT TGTTAAAGCTCAATATTGCATTCCCCAGTGATGAAGATATGTGCCAGAAGTTCCTCCAGCAGAACAGCTGGAATATCTTTCGGAAGGACC TGTTGCAGCTGCTCGTGGAGCCTTGCCAAAGTCAACTGTTCACTCCAAACCGGCCCAAGAAGAGAGAGATCTACAACCCTAAGTCTGTGG TCCTGGATTTGTGCAGCATCAACAAGACGACTAAACCTCGTTATCCTATTTTTATGGCACCCCAGAAATACCTCCCCCCATTGAGGATTG TCCAAGCCATCAAAGCACCTCGGTACAAAATCCGAGAACTCTTGGCTTAGTGTAAGAGCACAGGGGTCCTTATTTAGGACAAATAAAGGA >In-frame_PYGB_ENST00000216962_chr20_25273249_+_CNBD2_ENST00000538900_chr20_34575317_+_3153nt CGCAGTGCCGGGCGCCAGAGCAGCGGCGCCAGAGCAGCTGCACCATCCCGGCGTTCGCGTGTGCCGCCGCTTTCCTCCTCCATCTCTTTT CCTCCGCCTCCGCCGGCGCGATGGCGAAGCCGCTGACGGACAGCGAGAAGCGGAAGCAGATCAGCGTGCGCGGCCTGGCGGGGCTAGGCG ACGTGGCCGAGGTGCGGAAGAGCTTCAACCGGCACTTGCACTTCACGCTGGTCAAGGACCGCAATGTGGCCACGCCCCGCGACTACTTCT TCGCGCTGGCGCACACGGTGCGCGACCACCTCGTGGGCCGCTGGATCCGCACGCAGCAGCACTACTACGAGCGCGACCCCAAGCGCATTT ATTATCTTTCCCTGGAATTCTACATGGGTCGCACGCTGCAGAACACGATGGTGAACCTGGGCCTTCAGAATGCCTGCGATGAAGCCATCT ATCAGTTGGGGTTAGACTTGGAGGAACTCGAGGAGATAGAAGAAGATGCTGGCCTTGGGAATGGAGGCCTGGGGAGGCTGGCAGCGTGTT TCCTTGACTCAATGGCTACCTTGGGCCTGGCAGCATACGGCTATGGAATCCGCTATGAATTTGGGATTTTTAACCAGAAGATTGTCAATG GCTGGCAGGTAGAGGAGGCCGATGACTGGCTGCGCTACGGCAACCCCTGGGAGAAAGCGCGGCCTGAGTATATGCTTCCCGTGCACTTCT ACGGACGCGTGGAGCACACCCCCGACGGCGTGAAGTGGCTGGACACACAGGTGGTGCTGGCCATGCCCTACGACACCCCAGTGCCCGGCT ACAAGAACAACACCGTCAACACCATGCGGCTGTGGTCCGCCAAGGCTCCCAACGACTTCAAGCTGCAGGACTTCAACGTGGGAGACTACA TCGAGGCGGTCCTGGACCGGAACTTGGCTGAGAACATCTCCAGGGTCCTGTATCCAAATGATAACTTCTTTGAGGGGAAGGAGCTGCGGC TGAAGCAGGAGTACTTCGTGGTGGCCGCCACGCTCCAGGACATCATCCGCCGCTTCAAGTCGTCCAAGTTCGGCTGCCGGGACCCTGTGA GAACCTGTTTCGAGACGTTCCCAGACAAGGTGGCCATCCAGCTGAACGACACCCACCCCGCCCTCTCCATCCCTGAGCTCATGCGGATCC TGGTGGACGTGGAGAAGGTGGACTGGGACAAGGCCTGGGAAATCACGAAGAAGACCTGTGCATACACCAACCACACTGTGCTGCCTGAGG CCTTGGAGCGCTGGCCCGTGTCCATGTTTGAGAAGCTGCTGCCGCGGCACCTGGAGATAATCTATGCCATCAACCAGCGGCACCTGGACC ACGTGGCCGCGCTGTTTCCCGGCGATGTGGACCGCCTGCGCAGGATGTCTGTGATCGAGGAGGGGGACTGCAAGCGGATCAACATGGCCC ACCTGTGTGTGATTGGGTCCCATGCTGTCAATGGTGTGGCGAGGATCCACTCGGAGATCGTGAAACAGTCGGTCTTTAAGGATTTTTATG AACTGGAGCCAGAGAAGTTCCAGAATAAGACCAATGGCATCACCCCCCGCCGGTGGCTGCTGCTGTGCAACCCGGGGCTGGCCGATACCA TCGTGGAGAAAATTGGGGAGGAGTTCCTGACTGACCTGAGCCAGCTGAAGAAGCTGCTGCCGCTGGTCAGTGACGAGGTGTTCATCAGGG ACGTGGCCAAGGTCAAACAGGAGAACAAGCTCAAGTTCTCGGCCTTCCTGGAGAAGGAGTACAAGGTGAAGATCAACCCCTCCTCCATGT TCGATGTGCATGTGAAGAGGATCCACGAGTACAAGCGGCAGCTGCTCAACTGCCTGCACGTCGTCACCCTGTACAATCGAATCAAGAGAG ACCCGGCCAAGGCTTTTGTGCCCAGGACTGTTATGATTGGGGGCAAGGCAGCGCCCGGTTACCACATGGCCAAGCTGATCATCAAGTTGG TCACCTCCATCGGCGACGTCGTCAATCATGACCCAGTTGTGGGTGACAGGTTGAAAGTGATCTTCCTGGAGAACTACCGTGTGTCCTTGG CTGAGAAAGTGATCCCGGCCGCTGATCTGTCGCAGCAGATCTCCACTGCAGGCACCGAGGCCTCAGGCACAGGCAACATGAAGTTCATGC TCAACGGGGCCCTCACCATCGGCACCATGGACGGCGCCAACGTGGAGATGGCCGAGGAGGCCGGGGCCGAGAACCTCTTCATCTTCGGCC TGCGGGTGGAGGATGTCGAGGCCTTGGACCGGAAAGGGAAGATGGAGCTGTTTGCATCATGGTCTGATGAGAAGCTCTGGCAGCTGGTAG CCATGGCGAAGATAGAGAGGTTCTCGTATGGGCAGCTGATCTCAAAAGATTTTGGAGAGTCACCCTTCATCATGTTTATCAGCAAGGGCA GCTGTGAAGTCCTGCGGCTGTTGGACCTTGGGGCCTCCCCTTCCTACCGTAGATGGATCTGGCAGCACCTGGAGCTGATAGATGGCAGAC CTCTGAAGACCCACCTGAGTGAATACTCTCCTATGGAAAGATTTAAGGAATTCCAGATCAAATCATATCCTCTGCAAGACTTTAGCTCCT TGAAACTTCCACATCTCAAAAAAGCCTGGGGGCTACAGGGGACAAGCTTCAGCAGGAAGATCAGAACCTCAGGAGACACTCTCCCCAAGA TGCTGGGCCCGAAGATCCAATCCAGGCCTGCTCAGTCGATCAAATGTGCCATGATCAATATCAAGCCTGGTGAGCTCCCCAAGGAGGCTG CAGTGGGGGCCTACGTGAAGGTGCACACTGTGGAGCAGGGAGAAATTTTGTGATGAAGATATGTGCCAGAAGTTCCTCCAGCAGAACAGC TGGAATATCTTTCGGAAGGACCTGTTGCAGCTGCTCGTGGAGCCTTGCCAAAGTCAACTGTTCACTCCAAACCGGCCCAAGAAGAGAGAG ATCTACAACCCTAAGTCTGTGGTCCTGGATTTGTGCAGCATCAACAAGACGACTAAACCTCGTTATCCTATTTTTATGGCACCCCAGAAA TACCTCCCCCCATTGAGGATTGTCCAAGCCATCAAAGCACCTCGGTACAAAATCCGAGAACTCTTGGCTTAGTGTAAGAGCACAGGGGTC |
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FusionGenePPI for PYGB_CNBD2 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in . |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| PYGB | ACTN1, MLH1, SIRT7, CAND1, PSMB2, CPNE1, NPM1, FH, LIMD1, OGFOD1, PLCG1, RIC8A, UBR7, WDR61, UBA6, XPNPEP1, PYGB, PYGL, SIAH1, ARL6IP6, LIN37, NTF3, FSD1, STBD1, TMEM185A, HSD17B3, CCNL2, CYP1A1, ZFP41, ACLY, APOA1BP, GBE1, PFKL, C6orf211, NTRK1, SKI, MCM2, MCM5, SENP3, TMA16, BIN3, CD69, PRKAB2, GJB7, HMGN2, FGB, PMS1 | CNBD2 |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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RelatedDrugs for PYGB_CNBD2 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.0 2018-04-02) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
| Hgene | PYGB | P11216 | DB00114 | Pyridoxal Phosphate | Glycogen phosphorylase, brain form {ECO:0000303|PubMed:3346228} | small molecule | approved|investigational|nutraceutical |
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RelatedDiseases for PYGB_CNBD2 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
| Hgene | PYGB | C0010606 | Adenoid Cystic Carcinoma | 1 | CTD_human |
| Hgene | PYGB | C0036095 | Salivary Gland Neoplasms | 1 | CTD_human |
| Hgene | PYGB | C0151744 | Myocardial Ischemia | 1 | CTD_human |
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