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Center for Computational Systems Medicine
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FusionGeneSummary

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FusionProtFeature

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FusionGeneSequence

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FusionGenePPI

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RelatedDiseases

Fusion gene ID: 29515

FusionGeneSummary for PTPRG_CLASP2

check button Fusion gene summary
Fusion gene informationFusion gene name: PTPRG_CLASP2
Fusion gene ID: 29515
HgeneTgene
Gene symbol

PTPRG

CLASP2

Gene ID

5793

23122

Gene nameprotein tyrosine phosphatase, receptor type Gcytoplasmic linker associated protein 2
SynonymsHPTPG|PTPG|R-PTP-GAMMA|RPTPG-
Cytomap

3p14.2

3p22.3

Type of geneprotein-codingprotein-coding
Descriptionreceptor-type tyrosine-protein phosphatase gammaH_RG317H01.1protein tyrosine phosphatase gammaprotein tyrosine phosphatase, receptor type, gamma polypeptidereceptor type protein tyrosine phosphatase gammareceptor tyrosine phosphatase gammareceptor-tCLIP-associating protein 2CLIP-associating protein CLASP2multiple asters (Mast)-like homolog 2protein Orbit homolog 2
Modification date2018052720180522
UniProtAcc

P23470

O75122

Ensembl transtripts involved in fusion geneENST00000295874, ENST00000474889, 
ENST00000495879, 
ENST00000468888, 
ENST00000399362, ENST00000539981, 
ENST00000359576, ENST00000307312, 
ENST00000480013, ENST00000461133, 
ENST00000313350, ENST00000487200, 
ENST00000333778, ENST00000482896, 
Fusion gene scores* DoF score11 X 6 X 7=4629 X 5 X 6=270
# samples 139
** MAII scorelog2(13/462*10)=-1.8293812283876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(9/270*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PTPRG [Title/Abstract] AND CLASP2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVSARCTCGA-DX-A1KY-01APTPRGchr3

61989171

+CLASP2chr3

33543260

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000295874ENST00000468888PTPRGchr3

61989171

+CLASP2chr3

33543260

-
In-frameENST00000295874ENST00000399362PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-3UTRENST00000295874ENST00000539981PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-3UTRENST00000295874ENST00000359576PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-3UTRENST00000295874ENST00000307312PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-3UTRENST00000295874ENST00000480013PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-3UTRENST00000295874ENST00000461133PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-intronENST00000295874ENST00000313350PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-intronENST00000295874ENST00000487200PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-intronENST00000295874ENST00000333778PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-intronENST00000295874ENST00000482896PTPRGchr3

61989171

+CLASP2chr3

33543260

-
In-frameENST00000474889ENST00000468888PTPRGchr3

61989171

+CLASP2chr3

33543260

-
In-frameENST00000474889ENST00000399362PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-3UTRENST00000474889ENST00000539981PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-3UTRENST00000474889ENST00000359576PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-3UTRENST00000474889ENST00000307312PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-3UTRENST00000474889ENST00000480013PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-3UTRENST00000474889ENST00000461133PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-intronENST00000474889ENST00000313350PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-intronENST00000474889ENST00000487200PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-intronENST00000474889ENST00000333778PTPRGchr3

61989171

+CLASP2chr3

33543260

-
5CDS-intronENST00000474889ENST00000482896PTPRGchr3

61989171

+CLASP2chr3

33543260

-
intron-3CDSENST00000495879ENST00000468888PTPRGchr3

61989171

+CLASP2chr3

33543260

-
intron-3CDSENST00000495879ENST00000399362PTPRGchr3

61989171

+CLASP2chr3

33543260

-
intron-3UTRENST00000495879ENST00000539981PTPRGchr3

61989171

+CLASP2chr3

33543260

-
intron-3UTRENST00000495879ENST00000359576PTPRGchr3

61989171

+CLASP2chr3

33543260

-
intron-3UTRENST00000495879ENST00000307312PTPRGchr3

61989171

+CLASP2chr3

33543260

-
intron-3UTRENST00000495879ENST00000480013PTPRGchr3

61989171

+CLASP2chr3

33543260

-
intron-3UTRENST00000495879ENST00000461133PTPRGchr3

61989171

+CLASP2chr3

33543260

-
intron-intronENST00000495879ENST00000313350PTPRGchr3

61989171

+CLASP2chr3

33543260

-
intron-intronENST00000495879ENST00000487200PTPRGchr3

61989171

+CLASP2chr3

33543260

-
intron-intronENST00000495879ENST00000333778PTPRGchr3

61989171

+CLASP2chr3

33543260

-
intron-intronENST00000495879ENST00000482896PTPRGchr3

61989171

+CLASP2chr3

33543260

-

Top

FusionProtFeatures for PTPRG_CLASP2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PTPRG

P23470

CLASP2

O75122

Possesses tyrosine phosphatase activity.{ECO:0000269|PubMed:19167335}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-0131104_1108-59432Compositional biasNote=Poly-Leu
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-013310_587-59432Compositional biasNote=Ser-rich
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-0131017_1294-59432RegionNote=Required for cortical localization
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-01360_311-59432RegionTOG 1
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-013649_881-59432RegionTOG 2
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-0131054_1091-59432RepeatHEAT 6
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-0131098_1135-59432RepeatHEAT 7
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-0131216_1253-59432RepeatHEAT 8
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-013173_208-59432RepeatHEAT 1
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-013209_245-59432RepeatHEAT 2
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-013250_287-59432RepeatHEAT 3
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-013710_747-59432RepeatHEAT 4
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-013772_809-59432RepeatHEAT 5

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePTPRGchr3:61989171chr3:33543260ENST00000295874+4291150_14101731417DomainTyrosine-protein phosphatase 2
HgenePTPRGchr3:61989171chr3:33543260ENST00000295874+429349_4481731417DomainFibronectin type-III
HgenePTPRGchr3:61989171chr3:33543260ENST00000295874+42958_3211731417DomainAlpha-carbonic anhydrase
HgenePTPRGchr3:61989171chr3:33543260ENST00000295874+429848_11191731417DomainTyrosine-protein phosphatase 1
HgenePTPRGchr3:61989171chr3:33543260ENST00000474889+4301150_14101731446DomainTyrosine-protein phosphatase 2
HgenePTPRGchr3:61989171chr3:33543260ENST00000474889+430349_4481731446DomainFibronectin type-III
HgenePTPRGchr3:61989171chr3:33543260ENST00000474889+43058_3211731446DomainAlpha-carbonic anhydrase
HgenePTPRGchr3:61989171chr3:33543260ENST00000474889+430848_11191731446DomainTyrosine-protein phosphatase 1
HgenePTPRGchr3:61989171chr3:33543260ENST00000295874+4291060_10661731417RegionSubstrate binding
HgenePTPRGchr3:61989171chr3:33543260ENST00000474889+4301060_10661731446RegionSubstrate binding
HgenePTPRGchr3:61989171chr3:33543260ENST00000295874+42920_7361731417Topological domainExtracellular
HgenePTPRGchr3:61989171chr3:33543260ENST00000295874+429763_14451731417Topological domainCytoplasmic
HgenePTPRGchr3:61989171chr3:33543260ENST00000474889+43020_7361731446Topological domainExtracellular
HgenePTPRGchr3:61989171chr3:33543260ENST00000474889+430763_14451731446Topological domainCytoplasmic
HgenePTPRGchr3:61989171chr3:33543260ENST00000295874+429737_7621731417TransmembraneHelical
HgenePTPRGchr3:61989171chr3:33543260ENST00000474889+430737_7621731446TransmembraneHelical


Top

FusionGeneSequence for PTPRG_CLASP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_PTPRG_ENST00000295874_chr3_61989171_+_CLASP2_ENST00000468888_chr3_33543260_-_241aa
MRRLLEPCWWILFLKITSSVLHTVVCFPALTEGYVGALHENRHGSAVQIRRRKASGDPYWAYSGATGPEHWVTSSVSCGGRHQSPIDILD
QTARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDTFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSINGRRFPVEGTDNSES

>In-frame_PTPRG_ENST00000295874_chr3_61989171_+_CLASP2_ENST00000399362_chr3_33543260_-_241aa
MRRLLEPCWWILFLKITSSVLHTVVCFPALTEGYVGALHENRHGSAVQIRRRKASGDPYWAYSGATGPEHWVTSSVSCGGRHQSPIDILD
QTARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDTFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSINGRRFPVEGTDNSES

>In-frame_PTPRG_ENST00000474889_chr3_61989171_+_CLASP2_ENST00000468888_chr3_33543260_-_241aa
MRRLLEPCWWILFLKITSSVLHTVVCFPALTEGYVGALHENRHGSAVQIRRRKASGDPYWAYSGATGPEHWVTSSVSCGGRHQSPIDILD
QTARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDTFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSINGRRFPVEGTDNSES

>In-frame_PTPRG_ENST00000474889_chr3_61989171_+_CLASP2_ENST00000399362_chr3_33543260_-_241aa
MRRLLEPCWWILFLKITSSVLHTVVCFPALTEGYVGALHENRHGSAVQIRRRKASGDPYWAYSGATGPEHWVTSSVSCGGRHQSPIDILD
QTARVGEEYQELQLDGFDNESSNKTWMKNTGKTVAILLKDDTFVSGAGLPGRFKAEKVEFHWGHSNGSAGSEHSINGRRFPVEGTDNSES


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_PTPRG_ENST00000295874_chr3_61989171_+_CLASP2_ENST00000468888_chr3_33543260_-_723nt
ATGCGGAGGTTACTGGAACCGTGTTGGTGGATTTTGTTCCTGAAAATCACCAGTTCCGTGCTCCATTATGTCGTGTGCTTCCCCGCGTTG
ACAGAAGGCTACGTTGGGGCCCTGCACGAGAATAGACACGGCAGCGCAGTGCAGATCCGCAGGCGCAAGGCTTCAGGCGACCCGTACTGG
GCCTACTCTGGTGCCTATGGTCCTGAGCACTGGGTCACGTCTAGTGTCAGCTGTGGGGGCCGTCACCAGTCTCCTATTGACATTTTAGAC
CAGTATGCGCGTGTTGGGGAAGAATACCAGGAACTGCAACTCGATGGCTTCGACAATGAGTCTTCTAACAAAACCTGGATGAAAAACACA
GGGAAAACAGTCGCCATCCTTCTGAAAGACGACTATTTTGTCAGTGGAGCTGGTCTACCTGGCAGATTCAAAGCTGAGAAGGTGGAATTT
CACTGGGGCCACAGCAATGGCTCAGCGGGCTCTGAACACAGCATCAATGGCAGGAGGTTTCCTGTTGAGGGTTATGATAATTCAGAGAGC
AGTGTTCGGAAAGCTTGTGTCTTCTGCCTGGTGGCTGTTCATGCGGTAATTGGTGATGAACTAAAACCACATCTCAGTCAACTTACTGGC
AGTAAAATGAAGCTACTGAATCTTTACATCAAACGTGCACAAACAGGTTCTGGAGGAGCTGATCCCACTACTGATGTTTCTGGACAAAGT

>In-frame_PTPRG_ENST00000295874_chr3_61989171_+_CLASP2_ENST00000399362_chr3_33543260_-_723nt
ATGCGGAGGTTACTGGAACCGTGTTGGTGGATTTTGTTCCTGAAAATCACCAGTTCCGTGCTCCATTATGTCGTGTGCTTCCCCGCGTTG
ACAGAAGGCTACGTTGGGGCCCTGCACGAGAATAGACACGGCAGCGCAGTGCAGATCCGCAGGCGCAAGGCTTCAGGCGACCCGTACTGG
GCCTACTCTGGTGCCTATGGTCCTGAGCACTGGGTCACGTCTAGTGTCAGCTGTGGGGGCCGTCACCAGTCTCCTATTGACATTTTAGAC
CAGTATGCGCGTGTTGGGGAAGAATACCAGGAACTGCAACTCGATGGCTTCGACAATGAGTCTTCTAACAAAACCTGGATGAAAAACACA
GGGAAAACAGTCGCCATCCTTCTGAAAGACGACTATTTTGTCAGTGGAGCTGGTCTACCTGGCAGATTCAAAGCTGAGAAGGTGGAATTT
CACTGGGGCCACAGCAATGGCTCAGCGGGCTCTGAACACAGCATCAATGGCAGGAGGTTTCCTGTTGAGGGTTATGATAATTCAGAGAGC
AGTGTTCGGAAAGCTTGTGTCTTCTGCCTGGTGGCTGTTCATGCGGTAATTGGTGATGAACTAAAACCACATCTCAGTCAACTTACTGGC
AGTAAAATGAAGCTACTGAATCTTTACATCAAACGTGCACAAACAGGTTCTGGAGGAGCTGATCCCACTACTGATGTTTCTGGACAAAGT

>In-frame_PTPRG_ENST00000474889_chr3_61989171_+_CLASP2_ENST00000468888_chr3_33543260_-_723nt
ATGCGGAGGTTACTGGAACCGTGTTGGTGGATTTTGTTCCTGAAAATCACCAGTTCCGTGCTCCATTATGTCGTGTGCTTCCCCGCGTTG
ACAGAAGGCTACGTTGGGGCCCTGCACGAGAATAGACACGGCAGCGCAGTGCAGATCCGCAGGCGCAAGGCTTCAGGCGACCCGTACTGG
GCCTACTCTGGTGCCTATGGTCCTGAGCACTGGGTCACGTCTAGTGTCAGCTGTGGGGGCCGTCACCAGTCTCCTATTGACATTTTAGAC
CAGTATGCGCGTGTTGGGGAAGAATACCAGGAACTGCAACTCGATGGCTTCGACAATGAGTCTTCTAACAAAACCTGGATGAAAAACACA
GGGAAAACAGTCGCCATCCTTCTGAAAGACGACTATTTTGTCAGTGGAGCTGGTCTACCTGGCAGATTCAAAGCTGAGAAGGTGGAATTT
CACTGGGGCCACAGCAATGGCTCAGCGGGCTCTGAACACAGCATCAATGGCAGGAGGTTTCCTGTTGAGGGTTATGATAATTCAGAGAGC
AGTGTTCGGAAAGCTTGTGTCTTCTGCCTGGTGGCTGTTCATGCGGTAATTGGTGATGAACTAAAACCACATCTCAGTCAACTTACTGGC
AGTAAAATGAAGCTACTGAATCTTTACATCAAACGTGCACAAACAGGTTCTGGAGGAGCTGATCCCACTACTGATGTTTCTGGACAAAGT

>In-frame_PTPRG_ENST00000474889_chr3_61989171_+_CLASP2_ENST00000399362_chr3_33543260_-_723nt
ATGCGGAGGTTACTGGAACCGTGTTGGTGGATTTTGTTCCTGAAAATCACCAGTTCCGTGCTCCATTATGTCGTGTGCTTCCCCGCGTTG
ACAGAAGGCTACGTTGGGGCCCTGCACGAGAATAGACACGGCAGCGCAGTGCAGATCCGCAGGCGCAAGGCTTCAGGCGACCCGTACTGG
GCCTACTCTGGTGCCTATGGTCCTGAGCACTGGGTCACGTCTAGTGTCAGCTGTGGGGGCCGTCACCAGTCTCCTATTGACATTTTAGAC
CAGTATGCGCGTGTTGGGGAAGAATACCAGGAACTGCAACTCGATGGCTTCGACAATGAGTCTTCTAACAAAACCTGGATGAAAAACACA
GGGAAAACAGTCGCCATCCTTCTGAAAGACGACTATTTTGTCAGTGGAGCTGGTCTACCTGGCAGATTCAAAGCTGAGAAGGTGGAATTT
CACTGGGGCCACAGCAATGGCTCAGCGGGCTCTGAACACAGCATCAATGGCAGGAGGTTTCCTGTTGAGGGTTATGATAATTCAGAGAGC
AGTGTTCGGAAAGCTTGTGTCTTCTGCCTGGTGGCTGTTCATGCGGTAATTGGTGATGAACTAAAACCACATCTCAGTCAACTTACTGGC
AGTAAAATGAAGCTACTGAATCTTTACATCAAACGTGCACAAACAGGTTCTGGAGGAGCTGATCCCACTACTGATGTTTCTGGACAAAGT


* Fusion transcript sequences (Full-length transcript).
>In-frame_PTPRG_ENST00000295874_chr3_61989171_+_CLASP2_ENST00000468888_chr3_33543260_-_3486nt
CTCAAGTTGGGGATCCTCGGCTGCTCGCCGCCGCCGCCCGCGGTCCCTGCCTGCCCCAGGCCCGGGGCATCGCCGCCGGCCGCCGACTCC
GCGCCCTGCCCGATCGGCTCTCTCCTTTTTAAACGGAAAGCAGCCTTTCTCCGCCGAGAGGATCGTCCCCAGCGTGGCTCTGCGTTCCCG
GTCACTTTTTGAGATTTTCCGGGGGGCGCTCGGCGGCTTCCCGGATTCCAAGGGGACTCGGGCCGCCGAGCGCGGGGGGCCCGTGGAGCG
GGCGAGCCGGGGAAGCGCCCCGGCTTAGCGGAGGCTCGCACGGAGGCAAGAACTTATTCAACAAGTTTACCTCCCTGCTTTCCTCTTTTC
GATGTGCGTTTTCGGACATGCGGAGGTTACTGGAACCGTGTTGGTGGATTTTGTTCCTGAAAATCACCAGTTCCGTGCTCCATTATGTCG
TGTGCTTCCCCGCGTTGACAGAAGGCTACGTTGGGGCCCTGCACGAGAATAGACACGGCAGCGCAGTGCAGATCCGCAGGCGCAAGGCTT
CAGGCGACCCGTACTGGGCCTACTCTGGTGCCTATGGTCCTGAGCACTGGGTCACGTCTAGTGTCAGCTGTGGGGGCCGTCACCAGTCTC
CTATTGACATTTTAGACCAGTATGCGCGTGTTGGGGAAGAATACCAGGAACTGCAACTCGATGGCTTCGACAATGAGTCTTCTAACAAAA
CCTGGATGAAAAACACAGGGAAAACAGTCGCCATCCTTCTGAAAGACGACTATTTTGTCAGTGGAGCTGGTCTACCTGGCAGATTCAAAG
CTGAGAAGGTGGAATTTCACTGGGGCCACAGCAATGGCTCAGCGGGCTCTGAACACAGCATCAATGGCAGGAGGTTTCCTGTTGAGGGTT
ATGATAATTCAGAGAGCAGTGTTCGGAAAGCTTGTGTCTTCTGCCTGGTGGCTGTTCATGCGGTAATTGGTGATGAACTAAAACCACATC
TCAGTCAACTTACTGGCAGTAAAATGAAGCTACTGAATCTTTACATCAAACGTGCACAAACAGGTTCTGGAGGAGCTGATCCCACTACTG
ATGTTTCTGGACAAAGTTAGTGAAGCTCATCACAGCGAACCAGGTCTCTCAAAAGAAAGGACAGATAGACCACCCTCATCAATGAAAGGA
AGTTCTCAAACACATCCTTTGGAACTTACTATTGTTTCCCAGTTTTAGTTTTTTGTTTCGTTTCGTTTTGTATTTTCTGTAACAGAGGAC
TATCCTCAGTCTGCATGTAACTTTTATGATAGTTATTCCAAATTCAAGAAGAAGCAGTATTAACATCAATTGATCGACACAAAGTAATTT
TTAATTTAATTCATCATTTCACATGTTTGTACTTTGTCTTCCCATTAACCTTTGCCAGTGTTATGATTGTATAAATTTTTTTAAATGCTG
GTTAAACAGGAATGCTTAAAGCTTTAAAAGTTTAACAGTCTAAAACATTTTTGCTTTTATTCAACTGCAGAATAATATTTTTATTGCTAC
TTTGAGTTTTGTTTCGTATCATGTCCTATGCTAGAAATATTTAAATGATGTGAAACAAAGCAGGACTAATTTGAACTACAGCTGGACTCC
GTTTGTGTGATGGTGATACATGTCATTAGTTGCAACTTCTTTGGGGTGATCTATAGTTTGAAAACTAAAACCTCAAAGACAGATGTTACA
GAATCAGCCAGTTCTGTAAAACTGATATTGTCTATTGGTTATTGATCTTGCCATCTTTATTTAAAACCATGTCCCTTCTATGATCCCTTA
AGAAAGCTGCACCAAATCATCTGCCTGTTTTTTCTTGATACTTACTGAAATAGAAGGTTTTATTGCAGGGTTTATTTTGGTTTGTTTATA
TCTTTGTTGTGAATGATGCTTTTTTGTATTTATTAATATCAAATTCACTTATGAATAAACTTGATAATGGAAACGGACAAAAAAAATCAA
GTGCGTGTGTGTCCTTGACCGTCTTCTGTTTCTCACGTAATAAACAAATTATCGAGACATGGGAGTGACCAGCACCTTTTCTTTAAATGG
TGGAACCTGGTTTCCTTTTACCATGAAATTGTCTTACTTGAAAATATTGATCCTGATGAGAGAGAAGATGGTGCCAAGGCTGTCTTTGTA
TAATGGGCTCAAATTCTCTACCTCTTCAGGGCTAATACTTTTAACTGAGCTGCTGCCTATAGTGTCTTTTGGAAAACTACTTAAAGGGTG
ATTTTCTGTTACTTTTTAGCAAATTTTTTTAATCACCTCTTGCTACACCCATTCTTTTCATGTGCAGCCGACTCAAAAATTACCAGTTTT
GGTGAAAGGCTAAATTAGATAATTTGGAACCAGGATACTAATGATTTCTCATCTTTACTTTTTTTTAATCCTAATATAAAGTGAATTTGA
TTGAAAAGGCAAATAGCTATTAGGGAAGCAGTTTGCCATTGTTGCAGAGTTATCTGTACTTTGTTTAACTGAAAAAAATGTAGAAATATA
TGTAAAGAATTTAAGACAAGAGTACTGAATGGATGATTTGTCATAGGCTTTCCCCTTTCTTTCTGTTCTAGCAGCAGGAAAAGTTTCTCT
ATATCCTCTCCCTCTACCTGTAACAATTTTGTTTTCTACTGTTAATTACATTGTGTATTTATAGTTCTATGCTTACTGTTGTGCATATAC
TGGCAATAAAACTGTACATAACATTACTTGAAAAAGTTAATAATGTATATCAGTTTTTCTGTCTCACTGTGTAACAAGTCACTCAGTTTT
ATTTTAACTTTAGACGGTCTTGTATCAGTGGTGGTCTCTTGAATTTTGTAAGTTCATCTGAGGAGAAAAGATTTTTCAGGTGTAGCTACC
ACAATCAAAGGTATATAGCTACATACGCATGTATATATTACAGCTTATCTGTAAGAAGAAAATGCATTTTAAACACAACTCTTCTCAGTA
GCATTTTATGACCTTTGGATATGTTTGTAATCATTTCGAATCAAAATATTGATTTAATTTTGACCTCTGGTTTAAGATACTGCTTTAACT
ACTGTTGACAACCAAGTAGAGTGACTTAAGCTGAACAGTAACTAACTGGAAAATTAGATAAGCACCTGGCATCTAATGGCAGGCAGGCAC
TCAAGAAATGAATTAACTACATAATGGAAAAGTATGGTTTAATGTGTCCAAATGAAAGCTAGTAGATGTAAACATGGAAAAATTGTGTTT
ACAATTTTATAATCTCAGTTGATAAGACTATAAGAAAGCTGATTATTTAAATCACTATATACAATACACCCTTAATTTGTTCATTCCAGA
AACATACTGAGATGTCAGCTACTTAAAAATGGTCACAAAAAGCTACTGTTTATATTTTTCCTCCTGCTATTCTCTCCCAAATTAATTATT

>In-frame_PTPRG_ENST00000295874_chr3_61989171_+_CLASP2_ENST00000399362_chr3_33543260_-_3486nt
CTCAAGTTGGGGATCCTCGGCTGCTCGCCGCCGCCGCCCGCGGTCCCTGCCTGCCCCAGGCCCGGGGCATCGCCGCCGGCCGCCGACTCC
GCGCCCTGCCCGATCGGCTCTCTCCTTTTTAAACGGAAAGCAGCCTTTCTCCGCCGAGAGGATCGTCCCCAGCGTGGCTCTGCGTTCCCG
GTCACTTTTTGAGATTTTCCGGGGGGCGCTCGGCGGCTTCCCGGATTCCAAGGGGACTCGGGCCGCCGAGCGCGGGGGGCCCGTGGAGCG
GGCGAGCCGGGGAAGCGCCCCGGCTTAGCGGAGGCTCGCACGGAGGCAAGAACTTATTCAACAAGTTTACCTCCCTGCTTTCCTCTTTTC
GATGTGCGTTTTCGGACATGCGGAGGTTACTGGAACCGTGTTGGTGGATTTTGTTCCTGAAAATCACCAGTTCCGTGCTCCATTATGTCG
TGTGCTTCCCCGCGTTGACAGAAGGCTACGTTGGGGCCCTGCACGAGAATAGACACGGCAGCGCAGTGCAGATCCGCAGGCGCAAGGCTT
CAGGCGACCCGTACTGGGCCTACTCTGGTGCCTATGGTCCTGAGCACTGGGTCACGTCTAGTGTCAGCTGTGGGGGCCGTCACCAGTCTC
CTATTGACATTTTAGACCAGTATGCGCGTGTTGGGGAAGAATACCAGGAACTGCAACTCGATGGCTTCGACAATGAGTCTTCTAACAAAA
CCTGGATGAAAAACACAGGGAAAACAGTCGCCATCCTTCTGAAAGACGACTATTTTGTCAGTGGAGCTGGTCTACCTGGCAGATTCAAAG
CTGAGAAGGTGGAATTTCACTGGGGCCACAGCAATGGCTCAGCGGGCTCTGAACACAGCATCAATGGCAGGAGGTTTCCTGTTGAGGGTT
ATGATAATTCAGAGAGCAGTGTTCGGAAAGCTTGTGTCTTCTGCCTGGTGGCTGTTCATGCGGTAATTGGTGATGAACTAAAACCACATC
TCAGTCAACTTACTGGCAGTAAAATGAAGCTACTGAATCTTTACATCAAACGTGCACAAACAGGTTCTGGAGGAGCTGATCCCACTACTG
ATGTTTCTGGACAAAGTTAGTGAAGCTCATCACAGCGAACCAGGTCTCTCAAAAGAAAGGACAGATAGACCACCCTCATCAATGAAAGGA
AGTTCTCAAACACATCCTTTGGAACTTACTATTGTTTCCCAGTTTTAGTTTTTTGTTTCGTTTCGTTTTGTATTTTCTGTAACAGAGGAC
TATCCTCAGTCTGCATGTAACTTTTATGATAGTTATTCCAAATTCAAGAAGAAGCAGTATTAACATCAATTGATCGACACAAAGTAATTT
TTAATTTAATTCATCATTTCACATGTTTGTACTTTGTCTTCCCATTAACCTTTGCCAGTGTTATGATTGTATAAATTTTTTTAAATGCTG
GTTAAACAGGAATGCTTAAAGCTTTAAAAGTTTAACAGTCTAAAACATTTTTGCTTTTATTCAACTGCAGAATAATATTTTTATTGCTAC
TTTGAGTTTTGTTTCGTATCATGTCCTATGCTAGAAATATTTAAATGATGTGAAACAAAGCAGGACTAATTTGAACTACAGCTGGACTCC
GTTTGTGTGATGGTGATACATGTCATTAGTTGCAACTTCTTTGGGGTGATCTATAGTTTGAAAACTAAAACCTCAAAGACAGATGTTACA
GAATCAGCCAGTTCTGTAAAACTGATATTGTCTATTGGTTATTGATCTTGCCATCTTTATTTAAAACCATGTCCCTTCTATGATCCCTTA
AGAAAGCTGCACCAAATCATCTGCCTGTTTTTTCTTGATACTTACTGAAATAGAAGGTTTTATTGCAGGGTTTATTTTGGTTTGTTTATA
TCTTTGTTGTGAATGATGCTTTTTTGTATTTATTAATATCAAATTCACTTATGAATAAACTTGATAATGGAAACGGACAAAAAAAATCAA
GTGCGTGTGTGTCCTTGACCGTCTTCTGTTTCTCACGTAATAAACAAATTATCGAGACATGGGAGTGACCAGCACCTTTTCTTTAAATGG
TGGAACCTGGTTTCCTTTTACCATGAAATTGTCTTACTTGAAAATATTGATCCTGATGAGAGAGAAGATGGTGCCAAGGCTGTCTTTGTA
TAATGGGCTCAAATTCTCTACCTCTTCAGGGCTAATACTTTTAACTGAGCTGCTGCCTATAGTGTCTTTTGGAAAACTACTTAAAGGGTG
ATTTTCTGTTACTTTTTAGCAAATTTTTTTAATCACCTCTTGCTACACCCATTCTTTTCATGTGCAGCCGACTCAAAAATTACCAGTTTT
GGTGAAAGGCTAAATTAGATAATTTGGAACCAGGATACTAATGATTTCTCATCTTTACTTTTTTTTAATCCTAATATAAAGTGAATTTGA
TTGAAAAGGCAAATAGCTATTAGGGAAGCAGTTTGCCATTGTTGCAGAGTTATCTGTACTTTGTTTAACTGAAAAAAATGTAGAAATATA
TGTAAAGAATTTAAGACAAGAGTACTGAATGGATGATTTGTCATAGGCTTTCCCCTTTCTTTCTGTTCTAGCAGCAGGAAAAGTTTCTCT
ATATCCTCTCCCTCTACCTGTAACAATTTTGTTTTCTACTGTTAATTACATTGTGTATTTATAGTTCTATGCTTACTGTTGTGCATATAC
TGGCAATAAAACTGTACATAACATTACTTGAAAAAGTTAATAATGTATATCAGTTTTTCTGTCTCACTGTGTAACAAGTCACTCAGTTTT
ATTTTAACTTTAGACGGTCTTGTATCAGTGGTGGTCTCTTGAATTTTGTAAGTTCATCTGAGGAGAAAAGATTTTTCAGGTGTAGCTACC
ACAATCAAAGGTATATAGCTACATACGCATGTATATATTACAGCTTATCTGTAAGAAGAAAATGCATTTTAAACACAACTCTTCTCAGTA
GCATTTTATGACCTTTGGATATGTTTGTAATCATTTCGAATCAAAATATTGATTTAATTTTGACCTCTGGTTTAAGATACTGCTTTAACT
ACTGTTGACAACCAAGTAGAGTGACTTAAGCTGAACAGTAACTAACTGGAAAATTAGATAAGCACCTGGCATCTAATGGCAGGCAGGCAC
TCAAGAAATGAATTAACTACATAATGGAAAAGTATGGTTTAATGTGTCCAAATGAAAGCTAGTAGATGTAAACATGGAAAAATTGTGTTT
ACAATTTTATAATCTCAGTTGATAAGACTATAAGAAAGCTGATTATTTAAATCACTATATACAATACACCCTTAATTTGTTCATTCCAGA
AACATACTGAGATGTCAGCTACTTAAAAATGGTCACAAAAAGCTACTGTTTATATTTTTCCTCCTGCTATTCTCTCCCAAATTAATTATT

>In-frame_PTPRG_ENST00000474889_chr3_61989171_+_CLASP2_ENST00000468888_chr3_33543260_-_3486nt
CTCAAGTTGGGGATCCTCGGCTGCTCGCCGCCGCCGCCCGCGGTCCCTGCCTGCCCCAGGCCCGGGGCATCGCCGCCGGCCGCCGACTCC
GCGCCCTGCCCGATCGGCTCTCTCCTTTTTAAACGGAAAGCAGCCTTTCTCCGCCGAGAGGATCGTCCCCAGCGTGGCTCTGCGTTCCCG
GTCACTTTTTGAGATTTTCCGGGGGGCGCTCGGCGGCTTCCCGGATTCCAAGGGGACTCGGGCCGCCGAGCGCGGGGGGCCCGTGGAGCG
GGCGAGCCGGGGAAGCGCCCCGGCTTAGCGGAGGCTCGCACGGAGGCAAGAACTTATTCAACAAGTTTACCTCCCTGCTTTCCTCTTTTC
GATGTGCGTTTTCGGACATGCGGAGGTTACTGGAACCGTGTTGGTGGATTTTGTTCCTGAAAATCACCAGTTCCGTGCTCCATTATGTCG
TGTGCTTCCCCGCGTTGACAGAAGGCTACGTTGGGGCCCTGCACGAGAATAGACACGGCAGCGCAGTGCAGATCCGCAGGCGCAAGGCTT
CAGGCGACCCGTACTGGGCCTACTCTGGTGCCTATGGTCCTGAGCACTGGGTCACGTCTAGTGTCAGCTGTGGGGGCCGTCACCAGTCTC
CTATTGACATTTTAGACCAGTATGCGCGTGTTGGGGAAGAATACCAGGAACTGCAACTCGATGGCTTCGACAATGAGTCTTCTAACAAAA
CCTGGATGAAAAACACAGGGAAAACAGTCGCCATCCTTCTGAAAGACGACTATTTTGTCAGTGGAGCTGGTCTACCTGGCAGATTCAAAG
CTGAGAAGGTGGAATTTCACTGGGGCCACAGCAATGGCTCAGCGGGCTCTGAACACAGCATCAATGGCAGGAGGTTTCCTGTTGAGGGTT
ATGATAATTCAGAGAGCAGTGTTCGGAAAGCTTGTGTCTTCTGCCTGGTGGCTGTTCATGCGGTAATTGGTGATGAACTAAAACCACATC
TCAGTCAACTTACTGGCAGTAAAATGAAGCTACTGAATCTTTACATCAAACGTGCACAAACAGGTTCTGGAGGAGCTGATCCCACTACTG
ATGTTTCTGGACAAAGTTAGTGAAGCTCATCACAGCGAACCAGGTCTCTCAAAAGAAAGGACAGATAGACCACCCTCATCAATGAAAGGA
AGTTCTCAAACACATCCTTTGGAACTTACTATTGTTTCCCAGTTTTAGTTTTTTGTTTCGTTTCGTTTTGTATTTTCTGTAACAGAGGAC
TATCCTCAGTCTGCATGTAACTTTTATGATAGTTATTCCAAATTCAAGAAGAAGCAGTATTAACATCAATTGATCGACACAAAGTAATTT
TTAATTTAATTCATCATTTCACATGTTTGTACTTTGTCTTCCCATTAACCTTTGCCAGTGTTATGATTGTATAAATTTTTTTAAATGCTG
GTTAAACAGGAATGCTTAAAGCTTTAAAAGTTTAACAGTCTAAAACATTTTTGCTTTTATTCAACTGCAGAATAATATTTTTATTGCTAC
TTTGAGTTTTGTTTCGTATCATGTCCTATGCTAGAAATATTTAAATGATGTGAAACAAAGCAGGACTAATTTGAACTACAGCTGGACTCC
GTTTGTGTGATGGTGATACATGTCATTAGTTGCAACTTCTTTGGGGTGATCTATAGTTTGAAAACTAAAACCTCAAAGACAGATGTTACA
GAATCAGCCAGTTCTGTAAAACTGATATTGTCTATTGGTTATTGATCTTGCCATCTTTATTTAAAACCATGTCCCTTCTATGATCCCTTA
AGAAAGCTGCACCAAATCATCTGCCTGTTTTTTCTTGATACTTACTGAAATAGAAGGTTTTATTGCAGGGTTTATTTTGGTTTGTTTATA
TCTTTGTTGTGAATGATGCTTTTTTGTATTTATTAATATCAAATTCACTTATGAATAAACTTGATAATGGAAACGGACAAAAAAAATCAA
GTGCGTGTGTGTCCTTGACCGTCTTCTGTTTCTCACGTAATAAACAAATTATCGAGACATGGGAGTGACCAGCACCTTTTCTTTAAATGG
TGGAACCTGGTTTCCTTTTACCATGAAATTGTCTTACTTGAAAATATTGATCCTGATGAGAGAGAAGATGGTGCCAAGGCTGTCTTTGTA
TAATGGGCTCAAATTCTCTACCTCTTCAGGGCTAATACTTTTAACTGAGCTGCTGCCTATAGTGTCTTTTGGAAAACTACTTAAAGGGTG
ATTTTCTGTTACTTTTTAGCAAATTTTTTTAATCACCTCTTGCTACACCCATTCTTTTCATGTGCAGCCGACTCAAAAATTACCAGTTTT
GGTGAAAGGCTAAATTAGATAATTTGGAACCAGGATACTAATGATTTCTCATCTTTACTTTTTTTTAATCCTAATATAAAGTGAATTTGA
TTGAAAAGGCAAATAGCTATTAGGGAAGCAGTTTGCCATTGTTGCAGAGTTATCTGTACTTTGTTTAACTGAAAAAAATGTAGAAATATA
TGTAAAGAATTTAAGACAAGAGTACTGAATGGATGATTTGTCATAGGCTTTCCCCTTTCTTTCTGTTCTAGCAGCAGGAAAAGTTTCTCT
ATATCCTCTCCCTCTACCTGTAACAATTTTGTTTTCTACTGTTAATTACATTGTGTATTTATAGTTCTATGCTTACTGTTGTGCATATAC
TGGCAATAAAACTGTACATAACATTACTTGAAAAAGTTAATAATGTATATCAGTTTTTCTGTCTCACTGTGTAACAAGTCACTCAGTTTT
ATTTTAACTTTAGACGGTCTTGTATCAGTGGTGGTCTCTTGAATTTTGTAAGTTCATCTGAGGAGAAAAGATTTTTCAGGTGTAGCTACC
ACAATCAAAGGTATATAGCTACATACGCATGTATATATTACAGCTTATCTGTAAGAAGAAAATGCATTTTAAACACAACTCTTCTCAGTA
GCATTTTATGACCTTTGGATATGTTTGTAATCATTTCGAATCAAAATATTGATTTAATTTTGACCTCTGGTTTAAGATACTGCTTTAACT
ACTGTTGACAACCAAGTAGAGTGACTTAAGCTGAACAGTAACTAACTGGAAAATTAGATAAGCACCTGGCATCTAATGGCAGGCAGGCAC
TCAAGAAATGAATTAACTACATAATGGAAAAGTATGGTTTAATGTGTCCAAATGAAAGCTAGTAGATGTAAACATGGAAAAATTGTGTTT
ACAATTTTATAATCTCAGTTGATAAGACTATAAGAAAGCTGATTATTTAAATCACTATATACAATACACCCTTAATTTGTTCATTCCAGA
AACATACTGAGATGTCAGCTACTTAAAAATGGTCACAAAAAGCTACTGTTTATATTTTTCCTCCTGCTATTCTCTCCCAAATTAATTATT

>In-frame_PTPRG_ENST00000474889_chr3_61989171_+_CLASP2_ENST00000399362_chr3_33543260_-_3486nt
CTCAAGTTGGGGATCCTCGGCTGCTCGCCGCCGCCGCCCGCGGTCCCTGCCTGCCCCAGGCCCGGGGCATCGCCGCCGGCCGCCGACTCC
GCGCCCTGCCCGATCGGCTCTCTCCTTTTTAAACGGAAAGCAGCCTTTCTCCGCCGAGAGGATCGTCCCCAGCGTGGCTCTGCGTTCCCG
GTCACTTTTTGAGATTTTCCGGGGGGCGCTCGGCGGCTTCCCGGATTCCAAGGGGACTCGGGCCGCCGAGCGCGGGGGGCCCGTGGAGCG
GGCGAGCCGGGGAAGCGCCCCGGCTTAGCGGAGGCTCGCACGGAGGCAAGAACTTATTCAACAAGTTTACCTCCCTGCTTTCCTCTTTTC
GATGTGCGTTTTCGGACATGCGGAGGTTACTGGAACCGTGTTGGTGGATTTTGTTCCTGAAAATCACCAGTTCCGTGCTCCATTATGTCG
TGTGCTTCCCCGCGTTGACAGAAGGCTACGTTGGGGCCCTGCACGAGAATAGACACGGCAGCGCAGTGCAGATCCGCAGGCGCAAGGCTT
CAGGCGACCCGTACTGGGCCTACTCTGGTGCCTATGGTCCTGAGCACTGGGTCACGTCTAGTGTCAGCTGTGGGGGCCGTCACCAGTCTC
CTATTGACATTTTAGACCAGTATGCGCGTGTTGGGGAAGAATACCAGGAACTGCAACTCGATGGCTTCGACAATGAGTCTTCTAACAAAA
CCTGGATGAAAAACACAGGGAAAACAGTCGCCATCCTTCTGAAAGACGACTATTTTGTCAGTGGAGCTGGTCTACCTGGCAGATTCAAAG
CTGAGAAGGTGGAATTTCACTGGGGCCACAGCAATGGCTCAGCGGGCTCTGAACACAGCATCAATGGCAGGAGGTTTCCTGTTGAGGGTT
ATGATAATTCAGAGAGCAGTGTTCGGAAAGCTTGTGTCTTCTGCCTGGTGGCTGTTCATGCGGTAATTGGTGATGAACTAAAACCACATC
TCAGTCAACTTACTGGCAGTAAAATGAAGCTACTGAATCTTTACATCAAACGTGCACAAACAGGTTCTGGAGGAGCTGATCCCACTACTG
ATGTTTCTGGACAAAGTTAGTGAAGCTCATCACAGCGAACCAGGTCTCTCAAAAGAAAGGACAGATAGACCACCCTCATCAATGAAAGGA
AGTTCTCAAACACATCCTTTGGAACTTACTATTGTTTCCCAGTTTTAGTTTTTTGTTTCGTTTCGTTTTGTATTTTCTGTAACAGAGGAC
TATCCTCAGTCTGCATGTAACTTTTATGATAGTTATTCCAAATTCAAGAAGAAGCAGTATTAACATCAATTGATCGACACAAAGTAATTT
TTAATTTAATTCATCATTTCACATGTTTGTACTTTGTCTTCCCATTAACCTTTGCCAGTGTTATGATTGTATAAATTTTTTTAAATGCTG
GTTAAACAGGAATGCTTAAAGCTTTAAAAGTTTAACAGTCTAAAACATTTTTGCTTTTATTCAACTGCAGAATAATATTTTTATTGCTAC
TTTGAGTTTTGTTTCGTATCATGTCCTATGCTAGAAATATTTAAATGATGTGAAACAAAGCAGGACTAATTTGAACTACAGCTGGACTCC
GTTTGTGTGATGGTGATACATGTCATTAGTTGCAACTTCTTTGGGGTGATCTATAGTTTGAAAACTAAAACCTCAAAGACAGATGTTACA
GAATCAGCCAGTTCTGTAAAACTGATATTGTCTATTGGTTATTGATCTTGCCATCTTTATTTAAAACCATGTCCCTTCTATGATCCCTTA
AGAAAGCTGCACCAAATCATCTGCCTGTTTTTTCTTGATACTTACTGAAATAGAAGGTTTTATTGCAGGGTTTATTTTGGTTTGTTTATA
TCTTTGTTGTGAATGATGCTTTTTTGTATTTATTAATATCAAATTCACTTATGAATAAACTTGATAATGGAAACGGACAAAAAAAATCAA
GTGCGTGTGTGTCCTTGACCGTCTTCTGTTTCTCACGTAATAAACAAATTATCGAGACATGGGAGTGACCAGCACCTTTTCTTTAAATGG
TGGAACCTGGTTTCCTTTTACCATGAAATTGTCTTACTTGAAAATATTGATCCTGATGAGAGAGAAGATGGTGCCAAGGCTGTCTTTGTA
TAATGGGCTCAAATTCTCTACCTCTTCAGGGCTAATACTTTTAACTGAGCTGCTGCCTATAGTGTCTTTTGGAAAACTACTTAAAGGGTG
ATTTTCTGTTACTTTTTAGCAAATTTTTTTAATCACCTCTTGCTACACCCATTCTTTTCATGTGCAGCCGACTCAAAAATTACCAGTTTT
GGTGAAAGGCTAAATTAGATAATTTGGAACCAGGATACTAATGATTTCTCATCTTTACTTTTTTTTAATCCTAATATAAAGTGAATTTGA
TTGAAAAGGCAAATAGCTATTAGGGAAGCAGTTTGCCATTGTTGCAGAGTTATCTGTACTTTGTTTAACTGAAAAAAATGTAGAAATATA
TGTAAAGAATTTAAGACAAGAGTACTGAATGGATGATTTGTCATAGGCTTTCCCCTTTCTTTCTGTTCTAGCAGCAGGAAAAGTTTCTCT
ATATCCTCTCCCTCTACCTGTAACAATTTTGTTTTCTACTGTTAATTACATTGTGTATTTATAGTTCTATGCTTACTGTTGTGCATATAC
TGGCAATAAAACTGTACATAACATTACTTGAAAAAGTTAATAATGTATATCAGTTTTTCTGTCTCACTGTGTAACAAGTCACTCAGTTTT
ATTTTAACTTTAGACGGTCTTGTATCAGTGGTGGTCTCTTGAATTTTGTAAGTTCATCTGAGGAGAAAAGATTTTTCAGGTGTAGCTACC
ACAATCAAAGGTATATAGCTACATACGCATGTATATATTACAGCTTATCTGTAAGAAGAAAATGCATTTTAAACACAACTCTTCTCAGTA
GCATTTTATGACCTTTGGATATGTTTGTAATCATTTCGAATCAAAATATTGATTTAATTTTGACCTCTGGTTTAAGATACTGCTTTAACT
ACTGTTGACAACCAAGTAGAGTGACTTAAGCTGAACAGTAACTAACTGGAAAATTAGATAAGCACCTGGCATCTAATGGCAGGCAGGCAC
TCAAGAAATGAATTAACTACATAATGGAAAAGTATGGTTTAATGTGTCCAAATGAAAGCTAGTAGATGTAAACATGGAAAAATTGTGTTT
ACAATTTTATAATCTCAGTTGATAAGACTATAAGAAAGCTGATTATTTAAATCACTATATACAATACACCCTTAATTTGTTCATTCCAGA
AACATACTGAGATGTCAGCTACTTAAAAATGGTCACAAAAAGCTACTGTTTATATTTTTCCTCCTGCTATTCTCTCCCAAATTAATTATT


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FusionGenePPI for PTPRG_CLASP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
PTPRGDLG4, PTPRG, LGALS8, FYTTD1, FCN1, TMEM185A, CCNL2, DUSP26, PTPRB, SEC24A, FCHO2, CEP89, CDC42BPB, FAM129B, PSD3, PALM, CASKIN2, HSPA12A, GPRIN1, NF2, RPS15, CLNS1A, SLC39A10, ADD2, FARP1, GJB7, SDC1, DUS4L, MED21, PCDHGC3, DUSP22, ISG20, SERPINA12, ZNF517, ACBD7, NCSTN, NPB, SCGB2A2, CLCC1, DUSP23, DEFB104A, IER3IP1, PACS1, PTPRACLASP2SMYD2, LXN, CLIP2, MARK2, FEZ1, FEZ2, RAD21, TP53BP1, SMURF1, CSNK2A1, YWHAE, GRB2, MPG, PAN2, YWHAB, ASB3, GSK3B, MOV10, NXF1, MAPRE1, LYPD3, GOPC, FAM43A, NTRK1, AKT1, SRPK2, NIN, DCTN1, XPO1, CENPE, CENPJ, RC3H1, C10orf76, PPP4C, KLHDC3, CSGALNACT2, GORASP1, ID2, DCAF7


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-013444_580-59432microtubules%2C MAPRE1 and MAPRE3
TgeneCLASP2chr3:61989171chr3:33543260ENST00000313350-013872_1294-59432RSN and localization to the Golgi and kinetochores


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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RelatedDrugs for PTPRG_CLASP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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RelatedDiseases for PTPRG_CLASP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePTPRGC0038356Stomach Neoplasms1CTD_human