FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 29504

FusionGeneSummary for PTPRF_DHRS4L2

check button Fusion gene summary
Fusion gene informationFusion gene name: PTPRF_DHRS4L2
Fusion gene ID: 29504
HgeneTgene
Gene symbol

PTPRF

DHRS4L2

Gene ID

5792

317749

Gene nameprotein tyrosine phosphatase, receptor type Fdehydrogenase/reductase 4 like 2
SynonymsBNAH2|LARSDR25C3
Cytomap

1p34.2

14q11.2

Type of geneprotein-codingprotein-coding
Descriptionreceptor-type tyrosine-protein phosphatase FLCA-homologleukocyte antigen-related (LAR) PTP receptorleukocyte antigen-related tyrosine phosphataseleukocyte common antigen relatedprotein tyrosine phosphatase, receptor type, F polypeptidereceptor-linkedehydrogenase/reductase SDR family member 4-like 2NADP(H)-dependent retinol dehydrogenase/reductase short isoform-like proteinNADPH-dependent retinol dehydrogenase/reductase-like protein 2dehydrogenase/reductase (SDR family) member 4 like 2dehydrogena
Modification date2018052220180519
UniProtAcc

P10586

Q6PKH6

Ensembl transtripts involved in fusion geneENST00000359947, ENST00000438120, 
ENST00000372413, ENST00000372414, 
ENST00000422171, ENST00000496447, 
ENST00000534993, ENST00000543805, 
ENST00000397071, ENST00000335125, 
ENST00000558753, ENST00000537912, 
ENST00000545240, ENST00000382755, 
Fusion gene scores* DoF score10 X 9 X 7=6303 X 3 X 3=27
# samples 113
** MAII scorelog2(11/630*10)=-2.51784830486262
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: PTPRF [Title/Abstract] AND DHRS4L2 [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGARVREADTCGA-AF-2693-01APTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000359947ENST00000534993PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000359947ENST00000543805PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000359947ENST00000397071PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000359947ENST00000335125PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000359947ENST00000558753PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000359947ENST00000537912PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000359947ENST00000545240PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000359947ENST00000382755PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
In-frameENST00000438120ENST00000534993PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000438120ENST00000543805PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000438120ENST00000397071PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000438120ENST00000335125PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000438120ENST00000558753PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000438120ENST00000537912PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000438120ENST00000545240PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000438120ENST00000382755PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
In-frameENST00000372413ENST00000534993PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372413ENST00000543805PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372413ENST00000397071PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372413ENST00000335125PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372413ENST00000558753PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372413ENST00000537912PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372413ENST00000545240PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372413ENST00000382755PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
In-frameENST00000372414ENST00000534993PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372414ENST00000543805PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372414ENST00000397071PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372414ENST00000335125PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372414ENST00000558753PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372414ENST00000537912PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372414ENST00000545240PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000372414ENST00000382755PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
In-frameENST00000422171ENST00000534993PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000422171ENST00000543805PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000422171ENST00000397071PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000422171ENST00000335125PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000422171ENST00000558753PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000422171ENST00000537912PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000422171ENST00000545240PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
5CDS-intronENST00000422171ENST00000382755PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
3UTR-3CDSENST00000496447ENST00000534993PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
3UTR-intronENST00000496447ENST00000543805PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
3UTR-intronENST00000496447ENST00000397071PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
3UTR-intronENST00000496447ENST00000335125PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
3UTR-intronENST00000496447ENST00000558753PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
3UTR-intronENST00000496447ENST00000537912PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
3UTR-intronENST00000496447ENST00000545240PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+
3UTR-intronENST00000496447ENST00000382755PTPRFchr1

44064584

+DHRS4L2chr14

24464241

+

Top

FusionProtFeatures for PTPRF_DHRS4L2


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PTPRF

P10586

DHRS4L2

Q6PKH6

Possible cell adhesion receptor. It possesses anintrinsic protein tyrosine phosphatase activity (PTPase) anddephosphorylates EPHA2 regulating its activity. The first PTPase domain has enzymatic activity, whilethe second one seems to affect the substrate specificity of thefirst one. Probable oxidoreductase. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+1334135_2247711908DomainNote=Ig-like C2-type 2
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+1334232_3147711908DomainNote=Ig-like C2-type 3
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+1334321_4117711908DomainFibronectin type-III 1
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+133433_1237711908DomainNote=Ig-like C2-type 1
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+1334416_5107711908DomainFibronectin type-III 2
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+1334514_6047711908DomainFibronectin type-III 3
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+1334609_7067711908DomainFibronectin type-III 4
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+1131135_2247711899DomainNote=Ig-like C2-type 2
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+1131232_3147711899DomainNote=Ig-like C2-type 3
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+1131321_4117711899DomainFibronectin type-III 1
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+113133_1237711899DomainNote=Ig-like C2-type 1
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+1131416_5107711899DomainFibronectin type-III 2
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+1131514_6047711899DomainFibronectin type-III 3
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+1131609_7067711899DomainFibronectin type-III 4
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+1132135_2247711908DomainNote=Ig-like C2-type 2
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+1132232_3147711908DomainNote=Ig-like C2-type 3
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+1132321_4117711908DomainFibronectin type-III 1
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+113233_1237711908DomainNote=Ig-like C2-type 1
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+1132416_5107711908DomainFibronectin type-III 2
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+1132514_6047711908DomainFibronectin type-III 3
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+1132609_7067711908DomainFibronectin type-III 4
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+1333135_2247711899DomainNote=Ig-like C2-type 2
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+1333232_3147711899DomainNote=Ig-like C2-type 3
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+1333321_4117711899DomainFibronectin type-III 1
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+133333_1237711899DomainNote=Ig-like C2-type 1
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+1333416_5107711899DomainFibronectin type-III 2
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+1333514_6047711899DomainFibronectin type-III 3
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+1333609_7067711899DomainFibronectin type-III 4
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+133468_777711908RegionHeparin-binding
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+113168_777711899RegionHeparin-binding
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+113268_777711908RegionHeparin-binding
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+133368_777711899RegionHeparin-binding

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+13341014_10987711908DomainFibronectin type-III 8
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+13341352_16077711908DomainTyrosine-protein phosphatase 1
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+13341639_18987711908DomainTyrosine-protein phosphatase 2
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+1334711_8197711908DomainFibronectin type-III 5
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+1334820_9147711908DomainFibronectin type-III 6
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+1334918_10107711908DomainFibronectin type-III 7
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+11311014_10987711899DomainFibronectin type-III 8
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+11311352_16077711899DomainTyrosine-protein phosphatase 1
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+11311639_18987711899DomainTyrosine-protein phosphatase 2
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+1131711_8197711899DomainFibronectin type-III 5
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+1131820_9147711899DomainFibronectin type-III 6
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+1131918_10107711899DomainFibronectin type-III 7
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+11321014_10987711908DomainFibronectin type-III 8
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+11321352_16077711908DomainTyrosine-protein phosphatase 1
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+11321639_18987711908DomainTyrosine-protein phosphatase 2
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+1132711_8197711908DomainFibronectin type-III 5
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+1132820_9147711908DomainFibronectin type-III 6
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+1132918_10107711908DomainFibronectin type-III 7
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+13331014_10987711899DomainFibronectin type-III 8
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+13331352_16077711899DomainTyrosine-protein phosphatase 1
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+13331639_18987711899DomainTyrosine-protein phosphatase 2
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+1333711_8197711899DomainFibronectin type-III 5
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+1333820_9147711899DomainFibronectin type-III 6
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+1333918_10107711899DomainFibronectin type-III 7
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+13341548_15547711908RegionSubstrate binding
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+11311548_15547711899RegionSubstrate binding
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+11321548_15547711908RegionSubstrate binding
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+13331548_15547711899RegionSubstrate binding
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+13341285_19077711908Topological domainCytoplasmic
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+133430_12637711908Topological domainExtracellular
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+11311285_19077711899Topological domainCytoplasmic
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+113130_12637711899Topological domainExtracellular
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+11321285_19077711908Topological domainCytoplasmic
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+113230_12637711908Topological domainExtracellular
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+13331285_19077711899Topological domainCytoplasmic
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+133330_12637711899Topological domainExtracellular
HgenePTPRFchr1:44064584chr14:24464241ENST00000359947+13341264_12847711908TransmembraneHelical
HgenePTPRFchr1:44064584chr14:24464241ENST00000372413+11311264_12847711899TransmembraneHelical
HgenePTPRFchr1:44064584chr14:24464241ENST00000372414+11321264_12847711908TransmembraneHelical
HgenePTPRFchr1:44064584chr14:24464241ENST00000438120+13331264_12847711899TransmembraneHelical
TgeneDHRS4L2chr1:44064584chr14:24464241ENST00000335125+1834_58102322Nucleotide bindingNADP


Top

FusionGeneSequence for PTPRF_DHRS4L2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_PTPRF_ENST00000359947_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_862aa
MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSV
LRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS
NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAE
ELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE
GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVY
YTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI
IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPP
PADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL
NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKLWMDK

>In-frame_PTPRF_ENST00000438120_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_862aa
MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSV
LRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS
NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAE
ELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE
GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVY
YTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI
IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPP
PADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL
NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKLWMDK

>In-frame_PTPRF_ENST00000372413_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_862aa
MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSV
LRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS
NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAE
ELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE
GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVY
YTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI
IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPP
PADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL
NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKLWMDK

>In-frame_PTPRF_ENST00000372414_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_862aa
MAPEPAPGRTMVPLVPALVMLGLVAGAHGDSKPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSV
LRIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKARTATMLCAAGGNPDPEISWFKDFLPVDPATS
NGRIKQLRSGALQIESSEESDQGKYECVATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAE
ELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTE
GPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVY
YTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERI
IMYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPP
PADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPL
NSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKLWMDK

>In-frame_PTPRF_ENST00000422171_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_219aa
MYELVYWAAEDEDQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSMPSGPPRKVEVEPLNSTAVHVYWKLPV
PSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKLWMDKEKEESMKETLRIR


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_PTPRF_ENST00000359947_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_2586nt
ATGGCCCCTGAGCCAGCCCCAGGGAGGACGATGGTGCCCCTTGTGCCTGCACTGGTGATGCTTGGTTTGGTGGCAGGCGCCCATGGTGAC
AGCAAACCTGTCTTCATTAAAGTCCCTGAGGACCAGACTGGGCTGTCAGGAGGGGTAGCCTCCTTCGTGTGCCAAGCTACAGGAGAACCC
AAGCCGCGCATCACATGGATGAAGAAGGGGAAGAAAGTCAGCTCCCAGCGCTTCGAGGTCATTGAGTTTGATGATGGGGCAGGGTCAGTG
CTTCGGATCCAGCCATTGCGGGTGCAGCGAGATGAAGCCATCTATGAGTGTACAGCTACTAACAGCCTGGGTGAGATCAACACTAGTGCC
AAGCTCTCAGTGCTCGAAGAGGAACAGCTGCCCCCTGGGTTCCCTTCCATCGACATGGGGCCTCAGCTGAAGGTGGTGGAGAAGGCACGC
ACAGCCACCATGCTATGTGCCGCAGGCGGAAATCCAGACCCTGAGATTTCTTGGTTCAAGGACTTCCTTCCTGTAGACCCTGCCACGAGC
AACGGCCGCATCAAGCAGCTGCGTTCAGGTGCCTTGCAGATAGAGAGCAGTGAGGAATCCGACCAAGGCAAGTACGAGTGTGTGGCGACC
AACTCGGCAGGCACACGTTACTCAGCCCCTGCGAACCTGTATGTGCGAGTGCGCCGCGTGGCTCCTCGTTTCTCCATCCCTCCCAGCAGC
CAGGAGGTGATGCCAGGCGGCAGCGTGAACCTGACATGCGTGGCAGTGGGTGCACCCATGCCCTACGTGAAGTGGATGATGGGGGCCGAG
GAGCTCACCAAGGAGGATGAGATGCCAGTTGGCCGCAACGTCCTGGAGCTCAGCAATGTCGTACGCTCTGCCAACTACACCTGTGTGGCC
ATCTCCTCGCTGGGCATGATCGAGGCCACAGCCCAGGTCACAGTGAAAGCTCTTCCAAAGCCTCCGATTGATCTTGTGGTGACAGAGACA
ACTGCCACCAGTGTCACCCTCACCTGGGACTCTGGGAACTCGGAGCCTGTAACCTACTATGGCATCCAGTACCGCGCAGCGGGCACGGAG
GGCCCCTTTCAGGAGGTGGATGGTGTGGCCACCACCCGCTACAGCATTGGCGGCCTCAGCCCTTTCTCGGAATATGCCTTCCGCGTGCTG
GCGGTGAACAGCATCGGGCGAGGGCCGCCCAGCGAGGCAGTGCGGGCACGCACGGGAGAACAGGCGCCCTCCAGCCCACCGCGCCGCGTG
CAGGCACGCATGCTGAGCGCCAGCACCATGCTGGTGCAGTGGGAGCCTCCCGAGGAGCCCAACGGCCTGGTGCGGGGATACCGCGTCTAC
TATACTCCGGACTCCCGCCGCCCCCCGAACGCCTGGCACAAGCACAACACCGACGCGGGGCTCCTCACGACCGTGGGCAGCCTGCTGCCT
GGCATCACCTACAGCCTGCGCGTGCTTGCCTTCACCGCCGTGGGCGATGGCCCTCCCAGCCCCACCATCCAGGTCAAGACGCAGCAGGGA
GTGCCTGCCCAGCCCGCGGACTTCCAGGCCGAGGTGGAGTCGGACACCAGGATCCAGCTCTCGTGGCTGCTGCCCCCTCAGGAGCGGATC
ATCATGTATGAACTGGTGTACTGGGCGGCAGAGGACGAAGACCAACAGCACAAGGTGACCTTCGACCCAACCTCCTCCTACACACTAGAG
GACCTGAAGCCTGACACACTCTACCGCTTCCAGCTGGCTGCACGCTCGGATATGGGGGTGGGCGTCTTCACCCCCACCATTGAGGCCCGC
ACAGCCCAGTCCACCCCCTCCGCCCCTCCCCAGAAGGTGATGTGTGTGAGCATGGGCTCCACCACGGTCCGGGTAAGTTGGGTCCCGCCG
CCTGCCGACAGCCGCAACGGCGTTATCACCCAGTACTCCGTGGCCTACGAGGCGGTGGACGGCGAGGACCGCGGGCGGCATGTGGTGGAT
GGCATCAGCCGTGAGCACTCCAGCTGGGACCTGGTGGGCCTGGAGAAGTGGACGGAGTACCGGGTGTGGGTGCGGGCACACACAGACGTG
GGCCCCGGCCCCGAGAGCAGCCCGGTGCTGGTGCGCACCGATGAGGACGTGCCCAGCGGGCCTCCGCGGAAGGTGGAGGTGGAGCCACTG
AACTCCACTGCTGTGCATGTCTACTGGAAGCTGCCTGTCCCCAGCAAGCAGCATGGCCAGATCCGCGGCTACCAGGTCACCTACGTGCGG
CTGGAGAATGGCGAGCCCCGTGGACTCCCCATCATCCAAGACGTCATGCTAGCCGAGGCCCAGGCTGTGAAGCTTCATGGAGGTATCGAT
ATCCTAGTCTCCAATGCTGCTGTCAACCCTTTCTTTGGAAGCCTAATGGATGTCACCGAGGAGGTGTGGGACAAGCTCTGGATGGACAAG
GAAAAAGAGGAAAGCATGAAAGAAACCCTGCGGATAAGAAGGTTAGGCGAGCCAGAGGATTGTGCTGGCATCGTGTCTTTCCTGTGCTCT

>In-frame_PTPRF_ENST00000438120_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_2586nt
ATGGCCCCTGAGCCAGCCCCAGGGAGGACGATGGTGCCCCTTGTGCCTGCACTGGTGATGCTTGGTTTGGTGGCAGGCGCCCATGGTGAC
AGCAAACCTGTCTTCATTAAAGTCCCTGAGGACCAGACTGGGCTGTCAGGAGGGGTAGCCTCCTTCGTGTGCCAAGCTACAGGAGAACCC
AAGCCGCGCATCACATGGATGAAGAAGGGGAAGAAAGTCAGCTCCCAGCGCTTCGAGGTCATTGAGTTTGATGATGGGGCAGGGTCAGTG
CTTCGGATCCAGCCATTGCGGGTGCAGCGAGATGAAGCCATCTATGAGTGTACAGCTACTAACAGCCTGGGTGAGATCAACACTAGTGCC
AAGCTCTCAGTGCTCGAAGAGGAACAGCTGCCCCCTGGGTTCCCTTCCATCGACATGGGGCCTCAGCTGAAGGTGGTGGAGAAGGCACGC
ACAGCCACCATGCTATGTGCCGCAGGCGGAAATCCAGACCCTGAGATTTCTTGGTTCAAGGACTTCCTTCCTGTAGACCCTGCCACGAGC
AACGGCCGCATCAAGCAGCTGCGTTCAGGTGCCTTGCAGATAGAGAGCAGTGAGGAATCCGACCAAGGCAAGTACGAGTGTGTGGCGACC
AACTCGGCAGGCACACGTTACTCAGCCCCTGCGAACCTGTATGTGCGAGTGCGCCGCGTGGCTCCTCGTTTCTCCATCCCTCCCAGCAGC
CAGGAGGTGATGCCAGGCGGCAGCGTGAACCTGACATGCGTGGCAGTGGGTGCACCCATGCCCTACGTGAAGTGGATGATGGGGGCCGAG
GAGCTCACCAAGGAGGATGAGATGCCAGTTGGCCGCAACGTCCTGGAGCTCAGCAATGTCGTACGCTCTGCCAACTACACCTGTGTGGCC
ATCTCCTCGCTGGGCATGATCGAGGCCACAGCCCAGGTCACAGTGAAAGCTCTTCCAAAGCCTCCGATTGATCTTGTGGTGACAGAGACA
ACTGCCACCAGTGTCACCCTCACCTGGGACTCTGGGAACTCGGAGCCTGTAACCTACTATGGCATCCAGTACCGCGCAGCGGGCACGGAG
GGCCCCTTTCAGGAGGTGGATGGTGTGGCCACCACCCGCTACAGCATTGGCGGCCTCAGCCCTTTCTCGGAATATGCCTTCCGCGTGCTG
GCGGTGAACAGCATCGGGCGAGGGCCGCCCAGCGAGGCAGTGCGGGCACGCACGGGAGAACAGGCGCCCTCCAGCCCACCGCGCCGCGTG
CAGGCACGCATGCTGAGCGCCAGCACCATGCTGGTGCAGTGGGAGCCTCCCGAGGAGCCCAACGGCCTGGTGCGGGGATACCGCGTCTAC
TATACTCCGGACTCCCGCCGCCCCCCGAACGCCTGGCACAAGCACAACACCGACGCGGGGCTCCTCACGACCGTGGGCAGCCTGCTGCCT
GGCATCACCTACAGCCTGCGCGTGCTTGCCTTCACCGCCGTGGGCGATGGCCCTCCCAGCCCCACCATCCAGGTCAAGACGCAGCAGGGA
GTGCCTGCCCAGCCCGCGGACTTCCAGGCCGAGGTGGAGTCGGACACCAGGATCCAGCTCTCGTGGCTGCTGCCCCCTCAGGAGCGGATC
ATCATGTATGAACTGGTGTACTGGGCGGCAGAGGACGAAGACCAACAGCACAAGGTGACCTTCGACCCAACCTCCTCCTACACACTAGAG
GACCTGAAGCCTGACACACTCTACCGCTTCCAGCTGGCTGCACGCTCGGATATGGGGGTGGGCGTCTTCACCCCCACCATTGAGGCCCGC
ACAGCCCAGTCCACCCCCTCCGCCCCTCCCCAGAAGGTGATGTGTGTGAGCATGGGCTCCACCACGGTCCGGGTAAGTTGGGTCCCGCCG
CCTGCCGACAGCCGCAACGGCGTTATCACCCAGTACTCCGTGGCCTACGAGGCGGTGGACGGCGAGGACCGCGGGCGGCATGTGGTGGAT
GGCATCAGCCGTGAGCACTCCAGCTGGGACCTGGTGGGCCTGGAGAAGTGGACGGAGTACCGGGTGTGGGTGCGGGCACACACAGACGTG
GGCCCCGGCCCCGAGAGCAGCCCGGTGCTGGTGCGCACCGATGAGGACGTGCCCAGCGGGCCTCCGCGGAAGGTGGAGGTGGAGCCACTG
AACTCCACTGCTGTGCATGTCTACTGGAAGCTGCCTGTCCCCAGCAAGCAGCATGGCCAGATCCGCGGCTACCAGGTCACCTACGTGCGG
CTGGAGAATGGCGAGCCCCGTGGACTCCCCATCATCCAAGACGTCATGCTAGCCGAGGCCCAGGCTGTGAAGCTTCATGGAGGTATCGAT
ATCCTAGTCTCCAATGCTGCTGTCAACCCTTTCTTTGGAAGCCTAATGGATGTCACCGAGGAGGTGTGGGACAAGCTCTGGATGGACAAG
GAAAAAGAGGAAAGCATGAAAGAAACCCTGCGGATAAGAAGGTTAGGCGAGCCAGAGGATTGTGCTGGCATCGTGTCTTTCCTGTGCTCT

>In-frame_PTPRF_ENST00000372413_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_2586nt
ATGGCCCCTGAGCCAGCCCCAGGGAGGACGATGGTGCCCCTTGTGCCTGCACTGGTGATGCTTGGTTTGGTGGCAGGCGCCCATGGTGAC
AGCAAACCTGTCTTCATTAAAGTCCCTGAGGACCAGACTGGGCTGTCAGGAGGGGTAGCCTCCTTCGTGTGCCAAGCTACAGGAGAACCC
AAGCCGCGCATCACATGGATGAAGAAGGGGAAGAAAGTCAGCTCCCAGCGCTTCGAGGTCATTGAGTTTGATGATGGGGCAGGGTCAGTG
CTTCGGATCCAGCCATTGCGGGTGCAGCGAGATGAAGCCATCTATGAGTGTACAGCTACTAACAGCCTGGGTGAGATCAACACTAGTGCC
AAGCTCTCAGTGCTCGAAGAGGAACAGCTGCCCCCTGGGTTCCCTTCCATCGACATGGGGCCTCAGCTGAAGGTGGTGGAGAAGGCACGC
ACAGCCACCATGCTATGTGCCGCAGGCGGAAATCCAGACCCTGAGATTTCTTGGTTCAAGGACTTCCTTCCTGTAGACCCTGCCACGAGC
AACGGCCGCATCAAGCAGCTGCGTTCAGGTGCCTTGCAGATAGAGAGCAGTGAGGAATCCGACCAAGGCAAGTACGAGTGTGTGGCGACC
AACTCGGCAGGCACACGTTACTCAGCCCCTGCGAACCTGTATGTGCGAGTGCGCCGCGTGGCTCCTCGTTTCTCCATCCCTCCCAGCAGC
CAGGAGGTGATGCCAGGCGGCAGCGTGAACCTGACATGCGTGGCAGTGGGTGCACCCATGCCCTACGTGAAGTGGATGATGGGGGCCGAG
GAGCTCACCAAGGAGGATGAGATGCCAGTTGGCCGCAACGTCCTGGAGCTCAGCAATGTCGTACGCTCTGCCAACTACACCTGTGTGGCC
ATCTCCTCGCTGGGCATGATCGAGGCCACAGCCCAGGTCACAGTGAAAGCTCTTCCAAAGCCTCCGATTGATCTTGTGGTGACAGAGACA
ACTGCCACCAGTGTCACCCTCACCTGGGACTCTGGGAACTCGGAGCCTGTAACCTACTATGGCATCCAGTACCGCGCAGCGGGCACGGAG
GGCCCCTTTCAGGAGGTGGATGGTGTGGCCACCACCCGCTACAGCATTGGCGGCCTCAGCCCTTTCTCGGAATATGCCTTCCGCGTGCTG
GCGGTGAACAGCATCGGGCGAGGGCCGCCCAGCGAGGCAGTGCGGGCACGCACGGGAGAACAGGCGCCCTCCAGCCCACCGCGCCGCGTG
CAGGCACGCATGCTGAGCGCCAGCACCATGCTGGTGCAGTGGGAGCCTCCCGAGGAGCCCAACGGCCTGGTGCGGGGATACCGCGTCTAC
TATACTCCGGACTCCCGCCGCCCCCCGAACGCCTGGCACAAGCACAACACCGACGCGGGGCTCCTCACGACCGTGGGCAGCCTGCTGCCT
GGCATCACCTACAGCCTGCGCGTGCTTGCCTTCACCGCCGTGGGCGATGGCCCTCCCAGCCCCACCATCCAGGTCAAGACGCAGCAGGGA
GTGCCTGCCCAGCCCGCGGACTTCCAGGCCGAGGTGGAGTCGGACACCAGGATCCAGCTCTCGTGGCTGCTGCCCCCTCAGGAGCGGATC
ATCATGTATGAACTGGTGTACTGGGCGGCAGAGGACGAAGACCAACAGCACAAGGTGACCTTCGACCCAACCTCCTCCTACACACTAGAG
GACCTGAAGCCTGACACACTCTACCGCTTCCAGCTGGCTGCACGCTCGGATATGGGGGTGGGCGTCTTCACCCCCACCATTGAGGCCCGC
ACAGCCCAGTCCACCCCCTCCGCCCCTCCCCAGAAGGTGATGTGTGTGAGCATGGGCTCCACCACGGTCCGGGTAAGTTGGGTCCCGCCG
CCTGCCGACAGCCGCAACGGCGTTATCACCCAGTACTCCGTGGCCTACGAGGCGGTGGACGGCGAGGACCGCGGGCGGCATGTGGTGGAT
GGCATCAGCCGTGAGCACTCCAGCTGGGACCTGGTGGGCCTGGAGAAGTGGACGGAGTACCGGGTGTGGGTGCGGGCACACACAGACGTG
GGCCCCGGCCCCGAGAGCAGCCCGGTGCTGGTGCGCACCGATGAGGACGTGCCCAGCGGGCCTCCGCGGAAGGTGGAGGTGGAGCCACTG
AACTCCACTGCTGTGCATGTCTACTGGAAGCTGCCTGTCCCCAGCAAGCAGCATGGCCAGATCCGCGGCTACCAGGTCACCTACGTGCGG
CTGGAGAATGGCGAGCCCCGTGGACTCCCCATCATCCAAGACGTCATGCTAGCCGAGGCCCAGGCTGTGAAGCTTCATGGAGGTATCGAT
ATCCTAGTCTCCAATGCTGCTGTCAACCCTTTCTTTGGAAGCCTAATGGATGTCACCGAGGAGGTGTGGGACAAGCTCTGGATGGACAAG
GAAAAAGAGGAAAGCATGAAAGAAACCCTGCGGATAAGAAGGTTAGGCGAGCCAGAGGATTGTGCTGGCATCGTGTCTTTCCTGTGCTCT

>In-frame_PTPRF_ENST00000372414_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_2586nt
ATGGCCCCTGAGCCAGCCCCAGGGAGGACGATGGTGCCCCTTGTGCCTGCACTGGTGATGCTTGGTTTGGTGGCAGGCGCCCATGGTGAC
AGCAAACCTGTCTTCATTAAAGTCCCTGAGGACCAGACTGGGCTGTCAGGAGGGGTAGCCTCCTTCGTGTGCCAAGCTACAGGAGAACCC
AAGCCGCGCATCACATGGATGAAGAAGGGGAAGAAAGTCAGCTCCCAGCGCTTCGAGGTCATTGAGTTTGATGATGGGGCAGGGTCAGTG
CTTCGGATCCAGCCATTGCGGGTGCAGCGAGATGAAGCCATCTATGAGTGTACAGCTACTAACAGCCTGGGTGAGATCAACACTAGTGCC
AAGCTCTCAGTGCTCGAAGAGGAACAGCTGCCCCCTGGGTTCCCTTCCATCGACATGGGGCCTCAGCTGAAGGTGGTGGAGAAGGCACGC
ACAGCCACCATGCTATGTGCCGCAGGCGGAAATCCAGACCCTGAGATTTCTTGGTTCAAGGACTTCCTTCCTGTAGACCCTGCCACGAGC
AACGGCCGCATCAAGCAGCTGCGTTCAGGTGCCTTGCAGATAGAGAGCAGTGAGGAATCCGACCAAGGCAAGTACGAGTGTGTGGCGACC
AACTCGGCAGGCACACGTTACTCAGCCCCTGCGAACCTGTATGTGCGAGTGCGCCGCGTGGCTCCTCGTTTCTCCATCCCTCCCAGCAGC
CAGGAGGTGATGCCAGGCGGCAGCGTGAACCTGACATGCGTGGCAGTGGGTGCACCCATGCCCTACGTGAAGTGGATGATGGGGGCCGAG
GAGCTCACCAAGGAGGATGAGATGCCAGTTGGCCGCAACGTCCTGGAGCTCAGCAATGTCGTACGCTCTGCCAACTACACCTGTGTGGCC
ATCTCCTCGCTGGGCATGATCGAGGCCACAGCCCAGGTCACAGTGAAAGCTCTTCCAAAGCCTCCGATTGATCTTGTGGTGACAGAGACA
ACTGCCACCAGTGTCACCCTCACCTGGGACTCTGGGAACTCGGAGCCTGTAACCTACTATGGCATCCAGTACCGCGCAGCGGGCACGGAG
GGCCCCTTTCAGGAGGTGGATGGTGTGGCCACCACCCGCTACAGCATTGGCGGCCTCAGCCCTTTCTCGGAATATGCCTTCCGCGTGCTG
GCGGTGAACAGCATCGGGCGAGGGCCGCCCAGCGAGGCAGTGCGGGCACGCACGGGAGAACAGGCGCCCTCCAGCCCACCGCGCCGCGTG
CAGGCACGCATGCTGAGCGCCAGCACCATGCTGGTGCAGTGGGAGCCTCCCGAGGAGCCCAACGGCCTGGTGCGGGGATACCGCGTCTAC
TATACTCCGGACTCCCGCCGCCCCCCGAACGCCTGGCACAAGCACAACACCGACGCGGGGCTCCTCACGACCGTGGGCAGCCTGCTGCCT
GGCATCACCTACAGCCTGCGCGTGCTTGCCTTCACCGCCGTGGGCGATGGCCCTCCCAGCCCCACCATCCAGGTCAAGACGCAGCAGGGA
GTGCCTGCCCAGCCCGCGGACTTCCAGGCCGAGGTGGAGTCGGACACCAGGATCCAGCTCTCGTGGCTGCTGCCCCCTCAGGAGCGGATC
ATCATGTATGAACTGGTGTACTGGGCGGCAGAGGACGAAGACCAACAGCACAAGGTGACCTTCGACCCAACCTCCTCCTACACACTAGAG
GACCTGAAGCCTGACACACTCTACCGCTTCCAGCTGGCTGCACGCTCGGATATGGGGGTGGGCGTCTTCACCCCCACCATTGAGGCCCGC
ACAGCCCAGTCCACCCCCTCCGCCCCTCCCCAGAAGGTGATGTGTGTGAGCATGGGCTCCACCACGGTCCGGGTAAGTTGGGTCCCGCCG
CCTGCCGACAGCCGCAACGGCGTTATCACCCAGTACTCCGTGGCCTACGAGGCGGTGGACGGCGAGGACCGCGGGCGGCATGTGGTGGAT
GGCATCAGCCGTGAGCACTCCAGCTGGGACCTGGTGGGCCTGGAGAAGTGGACGGAGTACCGGGTGTGGGTGCGGGCACACACAGACGTG
GGCCCCGGCCCCGAGAGCAGCCCGGTGCTGGTGCGCACCGATGAGGACGTGCCCAGCGGGCCTCCGCGGAAGGTGGAGGTGGAGCCACTG
AACTCCACTGCTGTGCATGTCTACTGGAAGCTGCCTGTCCCCAGCAAGCAGCATGGCCAGATCCGCGGCTACCAGGTCACCTACGTGCGG
CTGGAGAATGGCGAGCCCCGTGGACTCCCCATCATCCAAGACGTCATGCTAGCCGAGGCCCAGGCTGTGAAGCTTCATGGAGGTATCGAT
ATCCTAGTCTCCAATGCTGCTGTCAACCCTTTCTTTGGAAGCCTAATGGATGTCACCGAGGAGGTGTGGGACAAGCTCTGGATGGACAAG
GAAAAAGAGGAAAGCATGAAAGAAACCCTGCGGATAAGAAGGTTAGGCGAGCCAGAGGATTGTGCTGGCATCGTGTCTTTCCTGTGCTCT

>In-frame_PTPRF_ENST00000422171_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_657nt
ATGTATGAACTGGTGTACTGGGCGGCAGAGGACGAAGACCAACAGCACAAGGTGACCTTCGACCCAACCTCCTCCTACACACTAGAGGAC
CTGAAGCCTGACACACTCTACCGCTTCCAGCTGGCTGCACGCTCGGATATGGGGGTGGGCGTCTTCACCCCCACCATTGAGGCCCGCACA
GCCCAGTCCATGCCCAGCGGGCCTCCGCGGAAGGTGGAGGTGGAGCCACTGAACTCCACTGCTGTGCATGTCTACTGGAAGCTGCCTGTC
CCCAGCAAGCAGCATGGCCAGATCCGCGGCTACCAGGTCACCTACGTGCGGCTGGAGAATGGCGAGCCCCGTGGACTCCCCATCATCCAA
GACGTCATGCTAGCCGAGGCCCAGGCTGTGAAGCTTCATGGAGGTATCGATATCCTAGTCTCCAATGCTGCTGTCAACCCTTTCTTTGGA
AGCCTAATGGATGTCACCGAGGAGGTGTGGGACAAGCTCTGGATGGACAAGGAAAAAGAGGAAAGCATGAAAGAAACCCTGCGGATAAGA
AGGTTAGGCGAGCCAGAGGATTGTGCTGGCATCGTGTCTTTCCTGTGCTCTGAAGATGCCAGCTACATCACTGGGGAAACAGTGGTGGTG


* Fusion transcript sequences (Full-length transcript).
>In-frame_PTPRF_ENST00000359947_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_3325nt
CGGGAGCGGCGGGAGCGGTGGCGGCGGCAGAGGCGGCGGCTCCAGCTTCGGCTCCGGCTCGGGCTCGGGCTCCGGCTCCGGCTCCGGCTC
CGGCTCCAGCTCGGGTGGCGGTGGCGGGAGCGGGACCAGGTGGAGGCGGCGGCGGCAGAGGAGTGGGAGCAGCGGCCCTAGCGGCTTGCG
GGGGGACATGCGGACCGACGGCCCCTGGATAGGCGGAAGGAGTGGAGGCCCTGGTGCCCGGCCCTTGGTGCTGAGTATCCAGCAAGAGTG
ACCGGGGTGAAGAAGCAAAGACTCGGTTGATTGTCCTGGGCTGTGGCTGGCTGTGGAGCTAGAGCCCTGGATGGCCCCTGAGCCAGCCCC
AGGGAGGACGATGGTGCCCCTTGTGCCTGCACTGGTGATGCTTGGTTTGGTGGCAGGCGCCCATGGTGACAGCAAACCTGTCTTCATTAA
AGTCCCTGAGGACCAGACTGGGCTGTCAGGAGGGGTAGCCTCCTTCGTGTGCCAAGCTACAGGAGAACCCAAGCCGCGCATCACATGGAT
GAAGAAGGGGAAGAAAGTCAGCTCCCAGCGCTTCGAGGTCATTGAGTTTGATGATGGGGCAGGGTCAGTGCTTCGGATCCAGCCATTGCG
GGTGCAGCGAGATGAAGCCATCTATGAGTGTACAGCTACTAACAGCCTGGGTGAGATCAACACTAGTGCCAAGCTCTCAGTGCTCGAAGA
GGAACAGCTGCCCCCTGGGTTCCCTTCCATCGACATGGGGCCTCAGCTGAAGGTGGTGGAGAAGGCACGCACAGCCACCATGCTATGTGC
CGCAGGCGGAAATCCAGACCCTGAGATTTCTTGGTTCAAGGACTTCCTTCCTGTAGACCCTGCCACGAGCAACGGCCGCATCAAGCAGCT
GCGTTCAGGTGCCTTGCAGATAGAGAGCAGTGAGGAATCCGACCAAGGCAAGTACGAGTGTGTGGCGACCAACTCGGCAGGCACACGTTA
CTCAGCCCCTGCGAACCTGTATGTGCGAGTGCGCCGCGTGGCTCCTCGTTTCTCCATCCCTCCCAGCAGCCAGGAGGTGATGCCAGGCGG
CAGCGTGAACCTGACATGCGTGGCAGTGGGTGCACCCATGCCCTACGTGAAGTGGATGATGGGGGCCGAGGAGCTCACCAAGGAGGATGA
GATGCCAGTTGGCCGCAACGTCCTGGAGCTCAGCAATGTCGTACGCTCTGCCAACTACACCTGTGTGGCCATCTCCTCGCTGGGCATGAT
CGAGGCCACAGCCCAGGTCACAGTGAAAGCTCTTCCAAAGCCTCCGATTGATCTTGTGGTGACAGAGACAACTGCCACCAGTGTCACCCT
CACCTGGGACTCTGGGAACTCGGAGCCTGTAACCTACTATGGCATCCAGTACCGCGCAGCGGGCACGGAGGGCCCCTTTCAGGAGGTGGA
TGGTGTGGCCACCACCCGCTACAGCATTGGCGGCCTCAGCCCTTTCTCGGAATATGCCTTCCGCGTGCTGGCGGTGAACAGCATCGGGCG
AGGGCCGCCCAGCGAGGCAGTGCGGGCACGCACGGGAGAACAGGCGCCCTCCAGCCCACCGCGCCGCGTGCAGGCACGCATGCTGAGCGC
CAGCACCATGCTGGTGCAGTGGGAGCCTCCCGAGGAGCCCAACGGCCTGGTGCGGGGATACCGCGTCTACTATACTCCGGACTCCCGCCG
CCCCCCGAACGCCTGGCACAAGCACAACACCGACGCGGGGCTCCTCACGACCGTGGGCAGCCTGCTGCCTGGCATCACCTACAGCCTGCG
CGTGCTTGCCTTCACCGCCGTGGGCGATGGCCCTCCCAGCCCCACCATCCAGGTCAAGACGCAGCAGGGAGTGCCTGCCCAGCCCGCGGA
CTTCCAGGCCGAGGTGGAGTCGGACACCAGGATCCAGCTCTCGTGGCTGCTGCCCCCTCAGGAGCGGATCATCATGTATGAACTGGTGTA
CTGGGCGGCAGAGGACGAAGACCAACAGCACAAGGTGACCTTCGACCCAACCTCCTCCTACACACTAGAGGACCTGAAGCCTGACACACT
CTACCGCTTCCAGCTGGCTGCACGCTCGGATATGGGGGTGGGCGTCTTCACCCCCACCATTGAGGCCCGCACAGCCCAGTCCACCCCCTC
CGCCCCTCCCCAGAAGGTGATGTGTGTGAGCATGGGCTCCACCACGGTCCGGGTAAGTTGGGTCCCGCCGCCTGCCGACAGCCGCAACGG
CGTTATCACCCAGTACTCCGTGGCCTACGAGGCGGTGGACGGCGAGGACCGCGGGCGGCATGTGGTGGATGGCATCAGCCGTGAGCACTC
CAGCTGGGACCTGGTGGGCCTGGAGAAGTGGACGGAGTACCGGGTGTGGGTGCGGGCACACACAGACGTGGGCCCCGGCCCCGAGAGCAG
CCCGGTGCTGGTGCGCACCGATGAGGACGTGCCCAGCGGGCCTCCGCGGAAGGTGGAGGTGGAGCCACTGAACTCCACTGCTGTGCATGT
CTACTGGAAGCTGCCTGTCCCCAGCAAGCAGCATGGCCAGATCCGCGGCTACCAGGTCACCTACGTGCGGCTGGAGAATGGCGAGCCCCG
TGGACTCCCCATCATCCAAGACGTCATGCTAGCCGAGGCCCAGGCTGTGAAGCTTCATGGAGGTATCGATATCCTAGTCTCCAATGCTGC
TGTCAACCCTTTCTTTGGAAGCCTAATGGATGTCACCGAGGAGGTGTGGGACAAGCTCTGGATGGACAAGGAAAAAGAGGAAAGCATGAA
AGAAACCCTGCGGATAAGAAGGTTAGGCGAGCCAGAGGATTGTGCTGGCATCGTGTCTTTCCTGTGCTCTGAAGATGCCAGCTACATCAC
TGGGGAAACAGTGGTGGTGGGTGGAGGAACCCCGTCCCGCCTCTGAGGACCGGGAGACAGCCCACAGGCCAGAGTTGGGCTCTAGCTCCT
GGTGCTGTTCCTGCATTCACCCACTGGCCTTTCCCACCTCTGCTCACCTTACTGTTCACCTCATCAAATCAGTTCTGCCCTGTGAAAAGA
TCCAGCCTTCCCTGCCGTCAAGGTGGCGTCTTACTCGGGATTCCTGCTGTTGTTGTGGCCTTGGGTAAAGGCCTCCCCTGAGAACACAGG
ACAGGCCTGCTGACAAGGCTGAGTCTACCTTGGCAAAGACCAAGATATTTTTTCCTGGGCCACTGGGGAATCTGAGGGGTGATGGGAGAG

>In-frame_PTPRF_ENST00000438120_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_3311nt
GCGGTGGCGGCGGCAGAGGCGGCGGCTCCAGCTTCGGCTCCGGCTCGGGCTCGGGCTCCGGCTCCGGCTCCGGCTCCGGCTCCAGCTCGG
GTGGCGGTGGCGGGAGCGGGACCAGGTGGAGGCGGCGGCGGCAGAGGAGTGGGAGCAGCGGCCCTAGCGGCTTGCGGGGGGACATGCGGA
CCGACGGCCCCTGGATAGGCGGAAGGAGTGGAGGCCCTGGTGCCCGGCCCTTGGTGCTGAGTATCCAGCAAGAGTGACCGGGGTGAAGAA
GCAAAGACTCGGTTGATTGTCCTGGGCTGTGGCTGGCTGTGGAGCTAGAGCCCTGGATGGCCCCTGAGCCAGCCCCAGGGAGGACGATGG
TGCCCCTTGTGCCTGCACTGGTGATGCTTGGTTTGGTGGCAGGCGCCCATGGTGACAGCAAACCTGTCTTCATTAAAGTCCCTGAGGACC
AGACTGGGCTGTCAGGAGGGGTAGCCTCCTTCGTGTGCCAAGCTACAGGAGAACCCAAGCCGCGCATCACATGGATGAAGAAGGGGAAGA
AAGTCAGCTCCCAGCGCTTCGAGGTCATTGAGTTTGATGATGGGGCAGGGTCAGTGCTTCGGATCCAGCCATTGCGGGTGCAGCGAGATG
AAGCCATCTATGAGTGTACAGCTACTAACAGCCTGGGTGAGATCAACACTAGTGCCAAGCTCTCAGTGCTCGAAGAGGAACAGCTGCCCC
CTGGGTTCCCTTCCATCGACATGGGGCCTCAGCTGAAGGTGGTGGAGAAGGCACGCACAGCCACCATGCTATGTGCCGCAGGCGGAAATC
CAGACCCTGAGATTTCTTGGTTCAAGGACTTCCTTCCTGTAGACCCTGCCACGAGCAACGGCCGCATCAAGCAGCTGCGTTCAGGTGCCT
TGCAGATAGAGAGCAGTGAGGAATCCGACCAAGGCAAGTACGAGTGTGTGGCGACCAACTCGGCAGGCACACGTTACTCAGCCCCTGCGA
ACCTGTATGTGCGAGTGCGCCGCGTGGCTCCTCGTTTCTCCATCCCTCCCAGCAGCCAGGAGGTGATGCCAGGCGGCAGCGTGAACCTGA
CATGCGTGGCAGTGGGTGCACCCATGCCCTACGTGAAGTGGATGATGGGGGCCGAGGAGCTCACCAAGGAGGATGAGATGCCAGTTGGCC
GCAACGTCCTGGAGCTCAGCAATGTCGTACGCTCTGCCAACTACACCTGTGTGGCCATCTCCTCGCTGGGCATGATCGAGGCCACAGCCC
AGGTCACAGTGAAAGCTCTTCCAAAGCCTCCGATTGATCTTGTGGTGACAGAGACAACTGCCACCAGTGTCACCCTCACCTGGGACTCTG
GGAACTCGGAGCCTGTAACCTACTATGGCATCCAGTACCGCGCAGCGGGCACGGAGGGCCCCTTTCAGGAGGTGGATGGTGTGGCCACCA
CCCGCTACAGCATTGGCGGCCTCAGCCCTTTCTCGGAATATGCCTTCCGCGTGCTGGCGGTGAACAGCATCGGGCGAGGGCCGCCCAGCG
AGGCAGTGCGGGCACGCACGGGAGAACAGGCGCCCTCCAGCCCACCGCGCCGCGTGCAGGCACGCATGCTGAGCGCCAGCACCATGCTGG
TGCAGTGGGAGCCTCCCGAGGAGCCCAACGGCCTGGTGCGGGGATACCGCGTCTACTATACTCCGGACTCCCGCCGCCCCCCGAACGCCT
GGCACAAGCACAACACCGACGCGGGGCTCCTCACGACCGTGGGCAGCCTGCTGCCTGGCATCACCTACAGCCTGCGCGTGCTTGCCTTCA
CCGCCGTGGGCGATGGCCCTCCCAGCCCCACCATCCAGGTCAAGACGCAGCAGGGAGTGCCTGCCCAGCCCGCGGACTTCCAGGCCGAGG
TGGAGTCGGACACCAGGATCCAGCTCTCGTGGCTGCTGCCCCCTCAGGAGCGGATCATCATGTATGAACTGGTGTACTGGGCGGCAGAGG
ACGAAGACCAACAGCACAAGGTGACCTTCGACCCAACCTCCTCCTACACACTAGAGGACCTGAAGCCTGACACACTCTACCGCTTCCAGC
TGGCTGCACGCTCGGATATGGGGGTGGGCGTCTTCACCCCCACCATTGAGGCCCGCACAGCCCAGTCCACCCCCTCCGCCCCTCCCCAGA
AGGTGATGTGTGTGAGCATGGGCTCCACCACGGTCCGGGTAAGTTGGGTCCCGCCGCCTGCCGACAGCCGCAACGGCGTTATCACCCAGT
ACTCCGTGGCCTACGAGGCGGTGGACGGCGAGGACCGCGGGCGGCATGTGGTGGATGGCATCAGCCGTGAGCACTCCAGCTGGGACCTGG
TGGGCCTGGAGAAGTGGACGGAGTACCGGGTGTGGGTGCGGGCACACACAGACGTGGGCCCCGGCCCCGAGAGCAGCCCGGTGCTGGTGC
GCACCGATGAGGACGTGCCCAGCGGGCCTCCGCGGAAGGTGGAGGTGGAGCCACTGAACTCCACTGCTGTGCATGTCTACTGGAAGCTGC
CTGTCCCCAGCAAGCAGCATGGCCAGATCCGCGGCTACCAGGTCACCTACGTGCGGCTGGAGAATGGCGAGCCCCGTGGACTCCCCATCA
TCCAAGACGTCATGCTAGCCGAGGCCCAGGCTGTGAAGCTTCATGGAGGTATCGATATCCTAGTCTCCAATGCTGCTGTCAACCCTTTCT
TTGGAAGCCTAATGGATGTCACCGAGGAGGTGTGGGACAAGCTCTGGATGGACAAGGAAAAAGAGGAAAGCATGAAAGAAACCCTGCGGA
TAAGAAGGTTAGGCGAGCCAGAGGATTGTGCTGGCATCGTGTCTTTCCTGTGCTCTGAAGATGCCAGCTACATCACTGGGGAAACAGTGG
TGGTGGGTGGAGGAACCCCGTCCCGCCTCTGAGGACCGGGAGACAGCCCACAGGCCAGAGTTGGGCTCTAGCTCCTGGTGCTGTTCCTGC
ATTCACCCACTGGCCTTTCCCACCTCTGCTCACCTTACTGTTCACCTCATCAAATCAGTTCTGCCCTGTGAAAAGATCCAGCCTTCCCTG
CCGTCAAGGTGGCGTCTTACTCGGGATTCCTGCTGTTGTTGTGGCCTTGGGTAAAGGCCTCCCCTGAGAACACAGGACAGGCCTGCTGAC
AAGGCTGAGTCTACCTTGGCAAAGACCAAGATATTTTTTCCTGGGCCACTGGGGAATCTGAGGGGTGATGGGAGAGAAGGAACCTGGAGT

>In-frame_PTPRF_ENST00000372413_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_3031nt
GGTTGATTGTCCTGGGCTGTGGCTGGCTGTGGAGCTAGAGCCCTGGATGGCCCCTGAGCCAGCCCCAGGGAGGACGATGGTGCCCCTTGT
GCCTGCACTGGTGATGCTTGGTTTGGTGGCAGGCGCCCATGGTGACAGCAAACCTGTCTTCATTAAAGTCCCTGAGGACCAGACTGGGCT
GTCAGGAGGGGTAGCCTCCTTCGTGTGCCAAGCTACAGGAGAACCCAAGCCGCGCATCACATGGATGAAGAAGGGGAAGAAAGTCAGCTC
CCAGCGCTTCGAGGTCATTGAGTTTGATGATGGGGCAGGGTCAGTGCTTCGGATCCAGCCATTGCGGGTGCAGCGAGATGAAGCCATCTA
TGAGTGTACAGCTACTAACAGCCTGGGTGAGATCAACACTAGTGCCAAGCTCTCAGTGCTCGAAGAGGAACAGCTGCCCCCTGGGTTCCC
TTCCATCGACATGGGGCCTCAGCTGAAGGTGGTGGAGAAGGCACGCACAGCCACCATGCTATGTGCCGCAGGCGGAAATCCAGACCCTGA
GATTTCTTGGTTCAAGGACTTCCTTCCTGTAGACCCTGCCACGAGCAACGGCCGCATCAAGCAGCTGCGTTCAGGTGCCTTGCAGATAGA
GAGCAGTGAGGAATCCGACCAAGGCAAGTACGAGTGTGTGGCGACCAACTCGGCAGGCACACGTTACTCAGCCCCTGCGAACCTGTATGT
GCGAGTGCGCCGCGTGGCTCCTCGTTTCTCCATCCCTCCCAGCAGCCAGGAGGTGATGCCAGGCGGCAGCGTGAACCTGACATGCGTGGC
AGTGGGTGCACCCATGCCCTACGTGAAGTGGATGATGGGGGCCGAGGAGCTCACCAAGGAGGATGAGATGCCAGTTGGCCGCAACGTCCT
GGAGCTCAGCAATGTCGTACGCTCTGCCAACTACACCTGTGTGGCCATCTCCTCGCTGGGCATGATCGAGGCCACAGCCCAGGTCACAGT
GAAAGCTCTTCCAAAGCCTCCGATTGATCTTGTGGTGACAGAGACAACTGCCACCAGTGTCACCCTCACCTGGGACTCTGGGAACTCGGA
GCCTGTAACCTACTATGGCATCCAGTACCGCGCAGCGGGCACGGAGGGCCCCTTTCAGGAGGTGGATGGTGTGGCCACCACCCGCTACAG
CATTGGCGGCCTCAGCCCTTTCTCGGAATATGCCTTCCGCGTGCTGGCGGTGAACAGCATCGGGCGAGGGCCGCCCAGCGAGGCAGTGCG
GGCACGCACGGGAGAACAGGCGCCCTCCAGCCCACCGCGCCGCGTGCAGGCACGCATGCTGAGCGCCAGCACCATGCTGGTGCAGTGGGA
GCCTCCCGAGGAGCCCAACGGCCTGGTGCGGGGATACCGCGTCTACTATACTCCGGACTCCCGCCGCCCCCCGAACGCCTGGCACAAGCA
CAACACCGACGCGGGGCTCCTCACGACCGTGGGCAGCCTGCTGCCTGGCATCACCTACAGCCTGCGCGTGCTTGCCTTCACCGCCGTGGG
CGATGGCCCTCCCAGCCCCACCATCCAGGTCAAGACGCAGCAGGGAGTGCCTGCCCAGCCCGCGGACTTCCAGGCCGAGGTGGAGTCGGA
CACCAGGATCCAGCTCTCGTGGCTGCTGCCCCCTCAGGAGCGGATCATCATGTATGAACTGGTGTACTGGGCGGCAGAGGACGAAGACCA
ACAGCACAAGGTGACCTTCGACCCAACCTCCTCCTACACACTAGAGGACCTGAAGCCTGACACACTCTACCGCTTCCAGCTGGCTGCACG
CTCGGATATGGGGGTGGGCGTCTTCACCCCCACCATTGAGGCCCGCACAGCCCAGTCCACCCCCTCCGCCCCTCCCCAGAAGGTGATGTG
TGTGAGCATGGGCTCCACCACGGTCCGGGTAAGTTGGGTCCCGCCGCCTGCCGACAGCCGCAACGGCGTTATCACCCAGTACTCCGTGGC
CTACGAGGCGGTGGACGGCGAGGACCGCGGGCGGCATGTGGTGGATGGCATCAGCCGTGAGCACTCCAGCTGGGACCTGGTGGGCCTGGA
GAAGTGGACGGAGTACCGGGTGTGGGTGCGGGCACACACAGACGTGGGCCCCGGCCCCGAGAGCAGCCCGGTGCTGGTGCGCACCGATGA
GGACGTGCCCAGCGGGCCTCCGCGGAAGGTGGAGGTGGAGCCACTGAACTCCACTGCTGTGCATGTCTACTGGAAGCTGCCTGTCCCCAG
CAAGCAGCATGGCCAGATCCGCGGCTACCAGGTCACCTACGTGCGGCTGGAGAATGGCGAGCCCCGTGGACTCCCCATCATCCAAGACGT
CATGCTAGCCGAGGCCCAGGCTGTGAAGCTTCATGGAGGTATCGATATCCTAGTCTCCAATGCTGCTGTCAACCCTTTCTTTGGAAGCCT
AATGGATGTCACCGAGGAGGTGTGGGACAAGCTCTGGATGGACAAGGAAAAAGAGGAAAGCATGAAAGAAACCCTGCGGATAAGAAGGTT
AGGCGAGCCAGAGGATTGTGCTGGCATCGTGTCTTTCCTGTGCTCTGAAGATGCCAGCTACATCACTGGGGAAACAGTGGTGGTGGGTGG
AGGAACCCCGTCCCGCCTCTGAGGACCGGGAGACAGCCCACAGGCCAGAGTTGGGCTCTAGCTCCTGGTGCTGTTCCTGCATTCACCCAC
TGGCCTTTCCCACCTCTGCTCACCTTACTGTTCACCTCATCAAATCAGTTCTGCCCTGTGAAAAGATCCAGCCTTCCCTGCCGTCAAGGT
GGCGTCTTACTCGGGATTCCTGCTGTTGTTGTGGCCTTGGGTAAAGGCCTCCCCTGAGAACACAGGACAGGCCTGCTGACAAGGCTGAGT
CTACCTTGGCAAAGACCAAGATATTTTTTCCTGGGCCACTGGGGAATCTGAGGGGTGATGGGAGAGAAGGAACCTGGAGTGGAAGGAGCA

>In-frame_PTPRF_ENST00000372414_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_3031nt
GGTTGATTGTCCTGGGCTGTGGCTGGCTGTGGAGCTAGAGCCCTGGATGGCCCCTGAGCCAGCCCCAGGGAGGACGATGGTGCCCCTTGT
GCCTGCACTGGTGATGCTTGGTTTGGTGGCAGGCGCCCATGGTGACAGCAAACCTGTCTTCATTAAAGTCCCTGAGGACCAGACTGGGCT
GTCAGGAGGGGTAGCCTCCTTCGTGTGCCAAGCTACAGGAGAACCCAAGCCGCGCATCACATGGATGAAGAAGGGGAAGAAAGTCAGCTC
CCAGCGCTTCGAGGTCATTGAGTTTGATGATGGGGCAGGGTCAGTGCTTCGGATCCAGCCATTGCGGGTGCAGCGAGATGAAGCCATCTA
TGAGTGTACAGCTACTAACAGCCTGGGTGAGATCAACACTAGTGCCAAGCTCTCAGTGCTCGAAGAGGAACAGCTGCCCCCTGGGTTCCC
TTCCATCGACATGGGGCCTCAGCTGAAGGTGGTGGAGAAGGCACGCACAGCCACCATGCTATGTGCCGCAGGCGGAAATCCAGACCCTGA
GATTTCTTGGTTCAAGGACTTCCTTCCTGTAGACCCTGCCACGAGCAACGGCCGCATCAAGCAGCTGCGTTCAGGTGCCTTGCAGATAGA
GAGCAGTGAGGAATCCGACCAAGGCAAGTACGAGTGTGTGGCGACCAACTCGGCAGGCACACGTTACTCAGCCCCTGCGAACCTGTATGT
GCGAGTGCGCCGCGTGGCTCCTCGTTTCTCCATCCCTCCCAGCAGCCAGGAGGTGATGCCAGGCGGCAGCGTGAACCTGACATGCGTGGC
AGTGGGTGCACCCATGCCCTACGTGAAGTGGATGATGGGGGCCGAGGAGCTCACCAAGGAGGATGAGATGCCAGTTGGCCGCAACGTCCT
GGAGCTCAGCAATGTCGTACGCTCTGCCAACTACACCTGTGTGGCCATCTCCTCGCTGGGCATGATCGAGGCCACAGCCCAGGTCACAGT
GAAAGCTCTTCCAAAGCCTCCGATTGATCTTGTGGTGACAGAGACAACTGCCACCAGTGTCACCCTCACCTGGGACTCTGGGAACTCGGA
GCCTGTAACCTACTATGGCATCCAGTACCGCGCAGCGGGCACGGAGGGCCCCTTTCAGGAGGTGGATGGTGTGGCCACCACCCGCTACAG
CATTGGCGGCCTCAGCCCTTTCTCGGAATATGCCTTCCGCGTGCTGGCGGTGAACAGCATCGGGCGAGGGCCGCCCAGCGAGGCAGTGCG
GGCACGCACGGGAGAACAGGCGCCCTCCAGCCCACCGCGCCGCGTGCAGGCACGCATGCTGAGCGCCAGCACCATGCTGGTGCAGTGGGA
GCCTCCCGAGGAGCCCAACGGCCTGGTGCGGGGATACCGCGTCTACTATACTCCGGACTCCCGCCGCCCCCCGAACGCCTGGCACAAGCA
CAACACCGACGCGGGGCTCCTCACGACCGTGGGCAGCCTGCTGCCTGGCATCACCTACAGCCTGCGCGTGCTTGCCTTCACCGCCGTGGG
CGATGGCCCTCCCAGCCCCACCATCCAGGTCAAGACGCAGCAGGGAGTGCCTGCCCAGCCCGCGGACTTCCAGGCCGAGGTGGAGTCGGA
CACCAGGATCCAGCTCTCGTGGCTGCTGCCCCCTCAGGAGCGGATCATCATGTATGAACTGGTGTACTGGGCGGCAGAGGACGAAGACCA
ACAGCACAAGGTGACCTTCGACCCAACCTCCTCCTACACACTAGAGGACCTGAAGCCTGACACACTCTACCGCTTCCAGCTGGCTGCACG
CTCGGATATGGGGGTGGGCGTCTTCACCCCCACCATTGAGGCCCGCACAGCCCAGTCCACCCCCTCCGCCCCTCCCCAGAAGGTGATGTG
TGTGAGCATGGGCTCCACCACGGTCCGGGTAAGTTGGGTCCCGCCGCCTGCCGACAGCCGCAACGGCGTTATCACCCAGTACTCCGTGGC
CTACGAGGCGGTGGACGGCGAGGACCGCGGGCGGCATGTGGTGGATGGCATCAGCCGTGAGCACTCCAGCTGGGACCTGGTGGGCCTGGA
GAAGTGGACGGAGTACCGGGTGTGGGTGCGGGCACACACAGACGTGGGCCCCGGCCCCGAGAGCAGCCCGGTGCTGGTGCGCACCGATGA
GGACGTGCCCAGCGGGCCTCCGCGGAAGGTGGAGGTGGAGCCACTGAACTCCACTGCTGTGCATGTCTACTGGAAGCTGCCTGTCCCCAG
CAAGCAGCATGGCCAGATCCGCGGCTACCAGGTCACCTACGTGCGGCTGGAGAATGGCGAGCCCCGTGGACTCCCCATCATCCAAGACGT
CATGCTAGCCGAGGCCCAGGCTGTGAAGCTTCATGGAGGTATCGATATCCTAGTCTCCAATGCTGCTGTCAACCCTTTCTTTGGAAGCCT
AATGGATGTCACCGAGGAGGTGTGGGACAAGCTCTGGATGGACAAGGAAAAAGAGGAAAGCATGAAAGAAACCCTGCGGATAAGAAGGTT
AGGCGAGCCAGAGGATTGTGCTGGCATCGTGTCTTTCCTGTGCTCTGAAGATGCCAGCTACATCACTGGGGAAACAGTGGTGGTGGGTGG
AGGAACCCCGTCCCGCCTCTGAGGACCGGGAGACAGCCCACAGGCCAGAGTTGGGCTCTAGCTCCTGGTGCTGTTCCTGCATTCACCCAC
TGGCCTTTCCCACCTCTGCTCACCTTACTGTTCACCTCATCAAATCAGTTCTGCCCTGTGAAAAGATCCAGCCTTCCCTGCCGTCAAGGT
GGCGTCTTACTCGGGATTCCTGCTGTTGTTGTGGCCTTGGGTAAAGGCCTCCCCTGAGAACACAGGACAGGCCTGCTGACAAGGCTGAGT
CTACCTTGGCAAAGACCAAGATATTTTTTCCTGGGCCACTGGGGAATCTGAGGGGTGATGGGAGAGAAGGAACCTGGAGTGGAAGGAGCA

>In-frame_PTPRF_ENST00000422171_chr1_44064584_+_DHRS4L2_ENST00000534993_chr14_24464241_+_1252nt
CAGCCTGCTGCCTGGCATCACCTACAGCCTGCGCGTGCTTGCCTTCACCGCCGTGGGCGATGGCCCTCCCAGCCCCACCATCCAGGTCAA
GACGCAGCAGGGAGTGCCTGCCCAGCCCGCGGACTTCCAGGCCGAGGTGGAGTCGGACACCAGGATCCAGCTCTCGTGGCTGCTGCCCCC
TCAGGAGCGGATCATCATGTATGAACTGGTGTACTGGGCGGCAGAGGACGAAGACCAACAGCACAAGGTGACCTTCGACCCAACCTCCTC
CTACACACTAGAGGACCTGAAGCCTGACACACTCTACCGCTTCCAGCTGGCTGCACGCTCGGATATGGGGGTGGGCGTCTTCACCCCCAC
CATTGAGGCCCGCACAGCCCAGTCCATGCCCAGCGGGCCTCCGCGGAAGGTGGAGGTGGAGCCACTGAACTCCACTGCTGTGCATGTCTA
CTGGAAGCTGCCTGTCCCCAGCAAGCAGCATGGCCAGATCCGCGGCTACCAGGTCACCTACGTGCGGCTGGAGAATGGCGAGCCCCGTGG
ACTCCCCATCATCCAAGACGTCATGCTAGCCGAGGCCCAGGCTGTGAAGCTTCATGGAGGTATCGATATCCTAGTCTCCAATGCTGCTGT
CAACCCTTTCTTTGGAAGCCTAATGGATGTCACCGAGGAGGTGTGGGACAAGCTCTGGATGGACAAGGAAAAAGAGGAAAGCATGAAAGA
AACCCTGCGGATAAGAAGGTTAGGCGAGCCAGAGGATTGTGCTGGCATCGTGTCTTTCCTGTGCTCTGAAGATGCCAGCTACATCACTGG
GGAAACAGTGGTGGTGGGTGGAGGAACCCCGTCCCGCCTCTGAGGACCGGGAGACAGCCCACAGGCCAGAGTTGGGCTCTAGCTCCTGGT
GCTGTTCCTGCATTCACCCACTGGCCTTTCCCACCTCTGCTCACCTTACTGTTCACCTCATCAAATCAGTTCTGCCCTGTGAAAAGATCC
AGCCTTCCCTGCCGTCAAGGTGGCGTCTTACTCGGGATTCCTGCTGTTGTTGTGGCCTTGGGTAAAGGCCTCCCCTGAGAACACAGGACA
GGCCTGCTGACAAGGCTGAGTCTACCTTGGCAAAGACCAAGATATTTTTTCCTGGGCCACTGGGGAATCTGAGGGGTGATGGGAGAGAAG


Top

FusionGenePPI for PTPRF_DHRS4L2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
PTPRFCTNNB1, GIT1, PPFIA1, RET, TRIO, CAV1, NID1, JUP, PPFIA3, PPFIA2, RYK, PRPF40A, SKIL, ZNF512B, EGFR, CUL7, ABCE1, CEACAM21, TGFBR2, SCN2B, HEPACAM2, UNK, NTRK1, ADRBK1, DNAAF5, NAA50, NPLOC4, PFKM, PICALM, PPWD1, ARPC3, HACL1, MAPK1, PPP2R5D, SEPHS1, TSTA3, UFD1L, CDKN2AIP, NUDCD3, TTI1, FAM171A2, SUGT1, PTPRS, WFDC2, IL13RA2, CLU, LRRIQ1, TMEM30B, PCDHGB1, ATP6V0E1, MANSC1, PCDHB16, MRAP2, PIANP, TRIM25DHRS4L2MTIF2, AARS2, DHRS4, ZZEF1, ACOT7, D2HGDH


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for PTPRF_DHRS4L2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for PTPRF_DHRS4L2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePTPRFC0038356Stomach Neoplasms1CTD_human
HgenePTPRFC0345967Malignant mesothelioma1CTD_human