FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 294

FusionGeneSummary for ABR_YWHAE

check button Fusion gene summary
Fusion gene informationFusion gene name: ABR_YWHAE
Fusion gene ID: 294
HgeneTgene
Gene symbol

ABR

YWHAE

Gene ID

29

7531

Gene nameABR, RhoGEF and GTPase activating proteintyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
SynonymsMDB14-3-3E|HEL2|KCIP-1|MDCR|MDS
Cytomap

17p13.3

17p13.3

Type of geneprotein-codingprotein-coding
Descriptionactive breakpoint cluster region-related proteinactive BCR-related14-3-3 protein epsilon14-3-3 epsilonepididymis luminal protein 2mitochondrial import stimulation factor L subunitprotein kinase C inhibitor protein-1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptidetyrosine
Modification date2018052320180522
UniProtAcc

Q12979

P62258

Ensembl transtripts involved in fusion geneENST00000302538, ENST00000544583, 
ENST00000572441, ENST00000574437, 
ENST00000291107, ENST00000543210, 
ENST00000536794, ENST00000573895, 
ENST00000264335, ENST00000571732, 
ENST00000573026, ENST00000575977, 
ENST00000498643, 
Fusion gene scores* DoF score13 X 10 X 13=169010 X 8 X 15=1200
# samples 2924
** MAII scorelog2(29/1690*10)=-2.54289844115461
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(24/1200*10)=-2.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ABR [Title/Abstract] AND YWHAE [Title/Abstract] AND fusion [Title/Abstract]

Japanese founder duplications/triplications involving BHLHA9 are associated with split-hand/foot malformation with or without long bone deficiency and Gollop-Wolfgang complex (pmid: 25351291)
Functional or gene categories assigned by FusionGDB annotationDDR (DNA damage repair) gene involved fusion gene, retained protein feature but frameshift.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneYWHAE

GO:0000165

MAPK cascade

12917326

TgeneYWHAE

GO:0034605

cellular response to heat

12917326

TgeneYWHAE

GO:0046827

positive regulation of protein export from nucleus

12917326

TgeneYWHAE

GO:0051480

regulation of cytosolic calcium ion concentration

18029012

TgeneYWHAE

GO:0060306

regulation of membrane repolarization

11953308

TgeneYWHAE

GO:1901016

regulation of potassium ion transmembrane transporter activity

11953308

TgeneYWHAE

GO:1901020

negative regulation of calcium ion transmembrane transporter activity

18029012

TgeneYWHAE

GO:1902309

negative regulation of peptidyl-serine dephosphorylation

11953308

TgeneYWHAE

GO:1905913

negative regulation of calcium ion export across plasma membrane

18029012


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
TCGALDBRCATCGA-E2-A106-01AABRchr17

1132087

-YWHAEchr17

1268352

-
TCGALDCOADTCGA-A6-2686-01AABRchr17

1132087

-YWHAEchr17

1268352

-
TCGALDCOADTCGA-G4-6294-01AABRchr17

1132087

-YWHAEchr17

1268352

-
TCGALDGBMTCGA-27-1831-01AABRchr17

1082961

-YWHAEchr17

1273035

-
TCGALDLAMLTCGA-AB-2832-03AABRchr17

1132087

-YWHAEchr17

1268352

-
TCGALDLAMLTCGA-AB-2884-03AABRchr17

1132087

-YWHAEchr17

1268352

-
TCGALDLAMLTCGA-AB-2920-03BABRchr17

1132087

-YWHAEchr17

1268352

-
TCGALDLAMLTCGA-AB-2984-03AABRchr17

1132087

-YWHAEchr17

1268352

-
TCGARVLGGTCGA-HT-7693-01AABRchr17

982570

-YWHAEchr17

1268352

-
TCGALDLGGTCGA-DU-6404-01AABRchr17

1132087

-YWHAEchr17

1248793

-
TCGALDLGGTCGA-RY-A847-01AABRchr17

1082961

-YWHAEchr17

1268352

-
TCGALDLUADTCGA-55-7576-01AABRchr17

953290

-YWHAEchr17

1257641

-
TCGALDSKCMTCGA-EE-A2GN-06AABRchr17

1082961

-YWHAEchr17

1268352

-
TCGALDSTADTCGA-FP-8631-01AABRchr17

1132087

-YWHAEchr17

1268352

-
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
intron-3CDSENST00000302538ENST00000264335ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-5UTRENST00000302538ENST00000571732ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000302538ENST00000573026ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000302538ENST00000575977ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000302538ENST00000498643ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-3CDSENST00000544583ENST00000264335ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-5UTRENST00000544583ENST00000571732ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000544583ENST00000573026ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000544583ENST00000575977ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000544583ENST00000498643ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-3CDSENST00000572441ENST00000264335ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-5UTRENST00000572441ENST00000571732ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000572441ENST00000573026ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000572441ENST00000575977ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000572441ENST00000498643ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-3CDSENST00000574437ENST00000264335ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-5UTRENST00000574437ENST00000571732ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000574437ENST00000573026ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000574437ENST00000575977ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000574437ENST00000498643ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-3CDSENST00000291107ENST00000264335ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-5UTRENST00000291107ENST00000571732ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000291107ENST00000573026ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000291107ENST00000575977ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000291107ENST00000498643ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-3CDSENST00000543210ENST00000264335ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-5UTRENST00000543210ENST00000571732ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000543210ENST00000573026ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000543210ENST00000575977ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000543210ENST00000498643ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-3CDSENST00000536794ENST00000264335ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-5UTRENST00000536794ENST00000571732ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000536794ENST00000573026ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000536794ENST00000575977ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000536794ENST00000498643ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-3CDSENST00000573895ENST00000264335ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-5UTRENST00000573895ENST00000571732ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000573895ENST00000573026ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000573895ENST00000575977ABRchr17

1132087

-YWHAEchr17

1268352

-
intron-intronENST00000573895ENST00000498643ABRchr17

1132087

-YWHAEchr17

1268352

-
5CDS-intronENST00000302538ENST00000264335ABRchr17

1082961

-YWHAEchr17

1273035

-
5CDS-5UTRENST00000302538ENST00000571732ABRchr17

1082961

-YWHAEchr17

1273035

-
5CDS-intronENST00000302538ENST00000573026ABRchr17

1082961

-YWHAEchr17

1273035

-
5CDS-intronENST00000302538ENST00000575977ABRchr17

1082961

-YWHAEchr17

1273035

-
5CDS-intronENST00000302538ENST00000498643ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000544583ENST00000264335ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-5UTRENST00000544583ENST00000571732ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000544583ENST00000573026ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000544583ENST00000575977ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000544583ENST00000498643ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000572441ENST00000264335ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-5UTRENST00000572441ENST00000571732ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000572441ENST00000573026ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000572441ENST00000575977ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000572441ENST00000498643ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000574437ENST00000264335ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-5UTRENST00000574437ENST00000571732ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000574437ENST00000573026ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000574437ENST00000575977ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000574437ENST00000498643ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000291107ENST00000264335ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-5UTRENST00000291107ENST00000571732ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000291107ENST00000573026ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000291107ENST00000575977ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000291107ENST00000498643ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000543210ENST00000264335ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-5UTRENST00000543210ENST00000571732ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000543210ENST00000573026ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000543210ENST00000575977ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000543210ENST00000498643ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000536794ENST00000264335ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-5UTRENST00000536794ENST00000571732ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000536794ENST00000573026ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000536794ENST00000575977ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000536794ENST00000498643ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000573895ENST00000264335ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-5UTRENST00000573895ENST00000571732ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000573895ENST00000573026ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000573895ENST00000575977ABRchr17

1082961

-YWHAEchr17

1273035

-
intron-intronENST00000573895ENST00000498643ABRchr17

1082961

-YWHAEchr17

1273035

-
In-frameENST00000302538ENST00000264335ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-5UTRENST00000302538ENST00000571732ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-intronENST00000302538ENST00000573026ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-intronENST00000302538ENST00000575977ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-intronENST00000302538ENST00000498643ABRchr17

982570

-YWHAEchr17

1268352

-
Frame-shiftENST00000544583ENST00000264335ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-5UTRENST00000544583ENST00000571732ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-intronENST00000544583ENST00000573026ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-intronENST00000544583ENST00000575977ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-intronENST00000544583ENST00000498643ABRchr17

982570

-YWHAEchr17

1268352

-
intron-3CDSENST00000572441ENST00000264335ABRchr17

982570

-YWHAEchr17

1268352

-
intron-5UTRENST00000572441ENST00000571732ABRchr17

982570

-YWHAEchr17

1268352

-
intron-intronENST00000572441ENST00000573026ABRchr17

982570

-YWHAEchr17

1268352

-
intron-intronENST00000572441ENST00000575977ABRchr17

982570

-YWHAEchr17

1268352

-
intron-intronENST00000572441ENST00000498643ABRchr17

982570

-YWHAEchr17

1268352

-
In-frameENST00000574437ENST00000264335ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-5UTRENST00000574437ENST00000571732ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-intronENST00000574437ENST00000573026ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-intronENST00000574437ENST00000575977ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-intronENST00000574437ENST00000498643ABRchr17

982570

-YWHAEchr17

1268352

-
In-frameENST00000291107ENST00000264335ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-5UTRENST00000291107ENST00000571732ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-intronENST00000291107ENST00000573026ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-intronENST00000291107ENST00000575977ABRchr17

982570

-YWHAEchr17

1268352

-
5CDS-intronENST00000291107ENST00000498643ABRchr17

982570

-YWHAEchr17

1268352

-
intron-3CDSENST00000543210ENST00000264335ABRchr17

982570

-YWHAEchr17

1268352

-
intron-5UTRENST00000543210ENST00000571732ABRchr17

982570

-YWHAEchr17

1268352

-
intron-intronENST00000543210ENST00000573026ABRchr17

982570

-YWHAEchr17

1268352

-
intron-intronENST00000543210ENST00000575977ABRchr17

982570

-YWHAEchr17

1268352

-
intron-intronENST00000543210ENST00000498643ABRchr17

982570

-YWHAEchr17

1268352

-
intron-3CDSENST00000536794ENST00000264335ABRchr17

982570

-YWHAEchr17

1268352

-
intron-5UTRENST00000536794ENST00000571732ABRchr17

982570

-YWHAEchr17

1268352

-
intron-intronENST00000536794ENST00000573026ABRchr17

982570

-YWHAEchr17

1268352

-
intron-intronENST00000536794ENST00000575977ABRchr17

982570

-YWHAEchr17

1268352

-
intron-intronENST00000536794ENST00000498643ABRchr17

982570

-YWHAEchr17

1268352

-
intron-3CDSENST00000573895ENST00000264335ABRchr17

982570

-YWHAEchr17

1268352

-
intron-5UTRENST00000573895ENST00000571732ABRchr17

982570

-YWHAEchr17

1268352

-
intron-intronENST00000573895ENST00000573026ABRchr17

982570

-YWHAEchr17

1268352

-
intron-intronENST00000573895ENST00000575977ABRchr17

982570

-YWHAEchr17

1268352

-
intron-intronENST00000573895ENST00000498643ABRchr17

982570

-YWHAEchr17

1268352

-
intron-3CDSENST00000302538ENST00000264335ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000302538ENST00000571732ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000302538ENST00000573026ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000302538ENST00000575977ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-intronENST00000302538ENST00000498643ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000544583ENST00000264335ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000544583ENST00000571732ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000544583ENST00000573026ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000544583ENST00000575977ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-intronENST00000544583ENST00000498643ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000572441ENST00000264335ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000572441ENST00000571732ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000572441ENST00000573026ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000572441ENST00000575977ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-intronENST00000572441ENST00000498643ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000574437ENST00000264335ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000574437ENST00000571732ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000574437ENST00000573026ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000574437ENST00000575977ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-intronENST00000574437ENST00000498643ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000291107ENST00000264335ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000291107ENST00000571732ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000291107ENST00000573026ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000291107ENST00000575977ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-intronENST00000291107ENST00000498643ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000543210ENST00000264335ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000543210ENST00000571732ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000543210ENST00000573026ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000543210ENST00000575977ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-intronENST00000543210ENST00000498643ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000536794ENST00000264335ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000536794ENST00000571732ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000536794ENST00000573026ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000536794ENST00000575977ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-intronENST00000536794ENST00000498643ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000573895ENST00000264335ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000573895ENST00000571732ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000573895ENST00000573026ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-3CDSENST00000573895ENST00000575977ABRchr17

1132087

-YWHAEchr17

1248793

-
intron-intronENST00000573895ENST00000498643ABRchr17

1132087

-YWHAEchr17

1248793

-
Frame-shiftENST00000302538ENST00000264335ABRchr17

1082961

-YWHAEchr17

1268352

-
5CDS-5UTRENST00000302538ENST00000571732ABRchr17

1082961

-YWHAEchr17

1268352

-
5CDS-intronENST00000302538ENST00000573026ABRchr17

1082961

-YWHAEchr17

1268352

-
5CDS-intronENST00000302538ENST00000575977ABRchr17

1082961

-YWHAEchr17

1268352

-
5CDS-intronENST00000302538ENST00000498643ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-3CDSENST00000544583ENST00000264335ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-5UTRENST00000544583ENST00000571732ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000544583ENST00000573026ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000544583ENST00000575977ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000544583ENST00000498643ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-3CDSENST00000572441ENST00000264335ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-5UTRENST00000572441ENST00000571732ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000572441ENST00000573026ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000572441ENST00000575977ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000572441ENST00000498643ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-3CDSENST00000574437ENST00000264335ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-5UTRENST00000574437ENST00000571732ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000574437ENST00000573026ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000574437ENST00000575977ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000574437ENST00000498643ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-3CDSENST00000291107ENST00000264335ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-5UTRENST00000291107ENST00000571732ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000291107ENST00000573026ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000291107ENST00000575977ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000291107ENST00000498643ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-3CDSENST00000543210ENST00000264335ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-5UTRENST00000543210ENST00000571732ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000543210ENST00000573026ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000543210ENST00000575977ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000543210ENST00000498643ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-3CDSENST00000536794ENST00000264335ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-5UTRENST00000536794ENST00000571732ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000536794ENST00000573026ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000536794ENST00000575977ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000536794ENST00000498643ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-3CDSENST00000573895ENST00000264335ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-5UTRENST00000573895ENST00000571732ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000573895ENST00000573026ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000573895ENST00000575977ABRchr17

1082961

-YWHAEchr17

1268352

-
intron-intronENST00000573895ENST00000498643ABRchr17

1082961

-YWHAEchr17

1268352

-
Frame-shiftENST00000302538ENST00000264335ABRchr17

953290

-YWHAEchr17

1257641

-
Frame-shiftENST00000302538ENST00000571732ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000302538ENST00000573026ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000302538ENST00000575977ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000302538ENST00000498643ABRchr17

953290

-YWHAEchr17

1257641

-
Frame-shiftENST00000544583ENST00000264335ABRchr17

953290

-YWHAEchr17

1257641

-
Frame-shiftENST00000544583ENST00000571732ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000544583ENST00000573026ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000544583ENST00000575977ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000544583ENST00000498643ABRchr17

953290

-YWHAEchr17

1257641

-
intron-3CDSENST00000572441ENST00000264335ABRchr17

953290

-YWHAEchr17

1257641

-
intron-3CDSENST00000572441ENST00000571732ABRchr17

953290

-YWHAEchr17

1257641

-
intron-intronENST00000572441ENST00000573026ABRchr17

953290

-YWHAEchr17

1257641

-
intron-intronENST00000572441ENST00000575977ABRchr17

953290

-YWHAEchr17

1257641

-
intron-intronENST00000572441ENST00000498643ABRchr17

953290

-YWHAEchr17

1257641

-
Frame-shiftENST00000574437ENST00000264335ABRchr17

953290

-YWHAEchr17

1257641

-
Frame-shiftENST00000574437ENST00000571732ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000574437ENST00000573026ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000574437ENST00000575977ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000574437ENST00000498643ABRchr17

953290

-YWHAEchr17

1257641

-
Frame-shiftENST00000291107ENST00000264335ABRchr17

953290

-YWHAEchr17

1257641

-
Frame-shiftENST00000291107ENST00000571732ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000291107ENST00000573026ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000291107ENST00000575977ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000291107ENST00000498643ABRchr17

953290

-YWHAEchr17

1257641

-
intron-3CDSENST00000543210ENST00000264335ABRchr17

953290

-YWHAEchr17

1257641

-
intron-3CDSENST00000543210ENST00000571732ABRchr17

953290

-YWHAEchr17

1257641

-
intron-intronENST00000543210ENST00000573026ABRchr17

953290

-YWHAEchr17

1257641

-
intron-intronENST00000543210ENST00000575977ABRchr17

953290

-YWHAEchr17

1257641

-
intron-intronENST00000543210ENST00000498643ABRchr17

953290

-YWHAEchr17

1257641

-
Frame-shiftENST00000536794ENST00000264335ABRchr17

953290

-YWHAEchr17

1257641

-
Frame-shiftENST00000536794ENST00000571732ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000536794ENST00000573026ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000536794ENST00000575977ABRchr17

953290

-YWHAEchr17

1257641

-
5CDS-intronENST00000536794ENST00000498643ABRchr17

953290

-YWHAEchr17

1257641

-
intron-3CDSENST00000573895ENST00000264335ABRchr17

953290

-YWHAEchr17

1257641

-
intron-3CDSENST00000573895ENST00000571732ABRchr17

953290

-YWHAEchr17

1257641

-
intron-intronENST00000573895ENST00000573026ABRchr17

953290

-YWHAEchr17

1257641

-
intron-intronENST00000573895ENST00000575977ABRchr17

953290

-YWHAEchr17

1257641

-
intron-intronENST00000573895ENST00000498643ABRchr17

953290

-YWHAEchr17

1257641

-

Top

FusionProtFeatures for ABR_YWHAE


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ABR

Q12979

YWHAE

P62258


check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
>>>>>>>>>>>>>>>>>>>>>>>>>
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABRchr17:982570chr17:1268352ENST00000291107-522417_420196823Compositional biasNote=Poly-Leu
HgeneABRchr17:982570chr17:1268352ENST00000302538-623417_420233860Compositional biasNote=Poly-Leu
HgeneABRchr17:982570chr17:1268352ENST00000543210-18417_420-33311Compositional biasNote=Poly-Leu
HgeneABRchr17:982570chr17:1268352ENST00000544583-623417_420187814Compositional biasNote=Poly-Leu
HgeneABRchr17:982570chr17:1268352ENST00000574437-522417_420187814Compositional biasNote=Poly-Leu
HgeneABRchr17:982570chr17:1268352ENST00000291107-522301_459196823DomainPH
HgeneABRchr17:982570chr17:1268352ENST00000291107-522463_595196823DomainC2
HgeneABRchr17:982570chr17:1268352ENST00000291107-522647_845196823DomainRho-GAP
HgeneABRchr17:982570chr17:1268352ENST00000291107-52291_284196823DomainDH
HgeneABRchr17:982570chr17:1268352ENST00000302538-623301_459233860DomainPH
HgeneABRchr17:982570chr17:1268352ENST00000302538-623463_595233860DomainC2
HgeneABRchr17:982570chr17:1268352ENST00000302538-623647_845233860DomainRho-GAP
HgeneABRchr17:982570chr17:1268352ENST00000302538-62391_284233860DomainDH
HgeneABRchr17:982570chr17:1268352ENST00000543210-18301_459-33311DomainPH
HgeneABRchr17:982570chr17:1268352ENST00000543210-18463_595-33311DomainC2
HgeneABRchr17:982570chr17:1268352ENST00000543210-18647_845-33311DomainRho-GAP
HgeneABRchr17:982570chr17:1268352ENST00000543210-1891_284-33311DomainDH
HgeneABRchr17:982570chr17:1268352ENST00000544583-623301_459187814DomainPH
HgeneABRchr17:982570chr17:1268352ENST00000544583-623463_595187814DomainC2
HgeneABRchr17:982570chr17:1268352ENST00000544583-623647_845187814DomainRho-GAP
HgeneABRchr17:982570chr17:1268352ENST00000544583-62391_284187814DomainDH
HgeneABRchr17:982570chr17:1268352ENST00000574437-522301_459187814DomainPH
HgeneABRchr17:982570chr17:1268352ENST00000574437-522463_595187814DomainC2
HgeneABRchr17:982570chr17:1268352ENST00000574437-522647_845187814DomainRho-GAP
HgeneABRchr17:982570chr17:1268352ENST00000574437-52291_284187814DomainDH


Top

FusionGeneSequence for ABR_YWHAE


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.
>In-frame_ABR_ENST00000302538_chr17_982570_-_YWHAE_ENST00000264335_chr17_1268352_-_468aa
MEPLSHRGLPRLSWIDTLYSNFSYGTDEYDGEGNEEQKGPPEGSETMPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLE
MRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQ
LGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRA
SWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENS
LVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRLAKAAFDDAIAELDTLSEESYKDSTLIMQLLRDNLTLWTSDMQGD

>In-frame_ABR_ENST00000574437_chr17_982570_-_YWHAE_ENST00000264335_chr17_1268352_-_422aa
MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTSQPVLTIQQI
ETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKVKGPKDSKDS
HTSVTMEEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDILDVL
DKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEILNSPDRACRL

>In-frame_ABR_ENST00000291107_chr17_982570_-_YWHAE_ENST00000264335_chr17_1268352_-_431aa
MEEEEEAIGLLDKVLEDEDVFLLEECELGTPTSPGSGSPFLVAVKVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATATTS
QPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQSNNQFQKISEELKV
KGPKDSKDSHTSVTMEEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKL
ICCDILDVLDKHLIPAANTGESKVFYYKMKGDYHRYLAEFATGNDRKEAAENSLVAYKAASDIAMTELPPTHPIRLGLALNFSVFYYEIL


* Fusion transcript sequences (only coding sequence (CDS) region).
>In-frame_ABR_ENST00000302538_chr17_982570_-_YWHAE_ENST00000264335_chr17_1268352_-_1404nt
ATGGAGCCGCTCAGCCACCGGGGCCTGCCGCGCCTGTCCTGGATCGACACCCTCTACAGCAACTTCAGCTACGGGACGGACGAGTACGAC
GGAGAGGGGAATGAGGAGCAGAAGGGGCCCCCGGAGGGCTCAGAGACCATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTC
AGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTCTCCCCGACTCCACCTGAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAG
ATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCCAGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTG
AAGGCCACCGCCACCACCTCCCAGCCCGTGCTCACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCAC
AAGGAGTTCTATGACAACCTGTGCCCCAAGGTGCAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAG
CTCGGTGTGTACAAAGCGTTTGTCGATAACTATAAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAG
ATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAGGACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGAAATGGTGGAGTCAATGAAG
AAAGTAGCAGGGATGGATGTGGAGCTGACAGTTGAAGAAAGAAACCTCCTATCTGTTGCATATAAGAATGTGATTGGAGCTAGAAGAGCC
TCCTGGAGAATAATCAGCAGCATTGAACAGAAAGAAGAAAACAAGGGAGGAGAAGACAAGCTAAAAATGATTCGGGAATATCGGCAAATG
GTTGAGACTGAGCTAAAGTTAATCTGTTGTGACATTCTGGATGTACTGGACAAACACCTCATTCCAGCAGCTAACACTGGCGAGTCCAAG
GTTTTCTATTATAAAATGAAAGGGGACTACCACAGGTATCTGGCAGAATTTGCCACAGGAAACGACAGGAAGGAGGCTGCGGAGAACAGC
CTAGTGGCTTATAAAGCTGCTAGTGATATTGCAATGACAGAACTTCCACCAACGCATCCTATTCGCTTAGGTCTTGCTCTCAATTTTTCC
GTATTCTACTACGAAATTCTTAATTCCCCTGACCGTGCCTGCAGGTTGGCAAAAGCAGCTTTTGATGATGCAATTGCAGAACTGGATACG
CTGAGTGAAGAAAGCTATAAGGACTCTACACTTATCATGCAGTTGTTACGTGATAATCTGACACTATGGACTTCAGACATGCAGGGTGAC

>In-frame_ABR_ENST00000574437_chr17_982570_-_YWHAE_ENST00000264335_chr17_1268352_-_1266nt
ATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTCAGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTCTCCCCGACTCCACCT
GAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCCAGCGAAGAGATCTAC
ATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTCACCATCCAGCAGATC
GAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTGCAACAGTGGGACAGC
CAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTATAAAGTCGCTCTGGAG
ACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAGGACTCCAAGGACAGC
CACACGTCTGTCACCATGGAAGAAATGGTGGAGTCAATGAAGAAAGTAGCAGGGATGGATGTGGAGCTGACAGTTGAAGAAAGAAACCTC
CTATCTGTTGCATATAAGAATGTGATTGGAGCTAGAAGAGCCTCCTGGAGAATAATCAGCAGCATTGAACAGAAAGAAGAAAACAAGGGA
GGAGAAGACAAGCTAAAAATGATTCGGGAATATCGGCAAATGGTTGAGACTGAGCTAAAGTTAATCTGTTGTGACATTCTGGATGTACTG
GACAAACACCTCATTCCAGCAGCTAACACTGGCGAGTCCAAGGTTTTCTATTATAAAATGAAAGGGGACTACCACAGGTATCTGGCAGAA
TTTGCCACAGGAAACGACAGGAAGGAGGCTGCGGAGAACAGCCTAGTGGCTTATAAAGCTGCTAGTGATATTGCAATGACAGAACTTCCA
CCAACGCATCCTATTCGCTTAGGTCTTGCTCTCAATTTTTCCGTATTCTACTACGAAATTCTTAATTCCCCTGACCGTGCCTGCAGGTTG
GCAAAAGCAGCTTTTGATGATGCAATTGCAGAACTGGATACGCTGAGTGAAGAAAGCTATAAGGACTCTACACTTATCATGCAGTTGTTA
CGTGATAATCTGACACTATGGACTTCAGACATGCAGGGTGACGGTGAAGAGCAGAATAAAGAAGCGCTGCAGGACGTGGAAGACGAAAAT

>In-frame_ABR_ENST00000291107_chr17_982570_-_YWHAE_ENST00000264335_chr17_1268352_-_1293nt
ATGGAGGAGGAAGAGGAGGCGATAGGCTTGCTGGACAAGGTTCTGGAGGACGAAGATGTGTTTCTCCTGGAGGAGTGCGAGCTGGGAACC
CCGACCAGCCCCGGCTCAGGGTCCCCCTTCCTGGTGGCTGTGAAGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCG
GGGTTCTTGGCCAGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCC
CAGCCCGTGCTCACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTG
TGCCCCAAGGTGCAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTT
GTCGATAACTATAAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTG
AAAGGTCCCAAGGACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGAAATGGTGGAGTCAATGAAGAAAGTAGCAGGGATGGATGTG
GAGCTGACAGTTGAAGAAAGAAACCTCCTATCTGTTGCATATAAGAATGTGATTGGAGCTAGAAGAGCCTCCTGGAGAATAATCAGCAGC
ATTGAACAGAAAGAAGAAAACAAGGGAGGAGAAGACAAGCTAAAAATGATTCGGGAATATCGGCAAATGGTTGAGACTGAGCTAAAGTTA
ATCTGTTGTGACATTCTGGATGTACTGGACAAACACCTCATTCCAGCAGCTAACACTGGCGAGTCCAAGGTTTTCTATTATAAAATGAAA
GGGGACTACCACAGGTATCTGGCAGAATTTGCCACAGGAAACGACAGGAAGGAGGCTGCGGAGAACAGCCTAGTGGCTTATAAAGCTGCT
AGTGATATTGCAATGACAGAACTTCCACCAACGCATCCTATTCGCTTAGGTCTTGCTCTCAATTTTTCCGTATTCTACTACGAAATTCTT
AATTCCCCTGACCGTGCCTGCAGGTTGGCAAAAGCAGCTTTTGATGATGCAATTGCAGAACTGGATACGCTGAGTGAAGAAAGCTATAAG
GACTCTACACTTATCATGCAGTTGTTACGTGATAATCTGACACTATGGACTTCAGACATGCAGGGTGACGGTGAAGAGCAGAATAAAGAA


* Fusion transcript sequences (Full-length transcript).
>In-frame_ABR_ENST00000302538_chr17_982570_-_YWHAE_ENST00000264335_chr17_1268352_-_2726nt
GCCCCGCGCTCCTCCCGGGGACCTGGTTCCCGGCCTCCTCGCCCCTCCGCGCTCGCAACTTCGGCCTCCCCCGGCTCCCGCCCGCTCTCC
CTCCTTTGTTGCGCGATGAGGGTCGGGTTTCGGATCTGACCGAGCCGCCGCCGCGGGATGGAGCCGCTCAGCCACCGGGGCCTGCCGCGC
CTGTCCTGGATCGACACCCTCTACAGCAACTTCAGCTACGGGACGGACGAGTACGACGGAGAGGGGAATGAGGAGCAGAAGGGGCCCCCG
GAGGGCTCAGAGACCATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTCAGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTC
TCCCCGACTCCACCTGAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCC
AGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTC
ACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTG
CAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTAT
AAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAG
GACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGAAATGGTGGAGTCAATGAAGAAAGTAGCAGGGATGGATGTGGAGCTGACAGTT
GAAGAAAGAAACCTCCTATCTGTTGCATATAAGAATGTGATTGGAGCTAGAAGAGCCTCCTGGAGAATAATCAGCAGCATTGAACAGAAA
GAAGAAAACAAGGGAGGAGAAGACAAGCTAAAAATGATTCGGGAATATCGGCAAATGGTTGAGACTGAGCTAAAGTTAATCTGTTGTGAC
ATTCTGGATGTACTGGACAAACACCTCATTCCAGCAGCTAACACTGGCGAGTCCAAGGTTTTCTATTATAAAATGAAAGGGGACTACCAC
AGGTATCTGGCAGAATTTGCCACAGGAAACGACAGGAAGGAGGCTGCGGAGAACAGCCTAGTGGCTTATAAAGCTGCTAGTGATATTGCA
ATGACAGAACTTCCACCAACGCATCCTATTCGCTTAGGTCTTGCTCTCAATTTTTCCGTATTCTACTACGAAATTCTTAATTCCCCTGAC
CGTGCCTGCAGGTTGGCAAAAGCAGCTTTTGATGATGCAATTGCAGAACTGGATACGCTGAGTGAAGAAAGCTATAAGGACTCTACACTT
ATCATGCAGTTGTTACGTGATAATCTGACACTATGGACTTCAGACATGCAGGGTGACGGTGAAGAGCAGAATAAAGAAGCGCTGCAGGAC
GTGGAAGACGAAAATCAGTGAGACATAAGCCAACAAGAGAAACCATCTCTGACCACCCCCTCCTCCCCATCCCACCCTTTGGAAACTCCC
CATTGTCACTGAGAACCACCAAATCTGACTTTTACATTTGGTCTCAGAATTTAGGTTCCTGCCCTGTTGGTTTTTTTTTTTTTTTTTTAA
ACAGTTTTCAAAAGTTCTTAAAGGCAAGAGTGAATTTCTGTGGATTTTACTGGTCCCAGCTTTTAGGTTCTTTAAGACACTAACAGGACT
ACATAGAGGCTTTTTCAGCATTACTGTGTCGTCTCCGTGCCAGATGTGGCAAGATCACCATTAGCAAATGGAAATTACATTTGAAAGCCA
TTAGACTTATAGGTGATGCAAGCATCTAAGAGAGAGGTTAATCACACTATAGAGGCATAAGTGGTATCAGTTTTCATTTTTCTAATTGTT
TAAACTGTGTTTTATACCAGTGTTTGCAAGTAATTGGGTGTTAGCTTGAGATGGTTAAAGGTGGTTTGGGGAGGGACTTCGTTGTAATGG
TTTTGCTGTAAAAAATGTTTCCAACTCCGCTGAAATGTTGCTGAAAAGCATGGTGCTGGTAACAGTTCAACAATCCGTGGCTGCTCATTC
TTGCCTACTTTACTCTCCCACTGAAGCAGGTTAGCGTTGAAGGTGGTATGGAAAAGCCTGCATGCCTGTTCAATTCTTTTGTTTCTTCTC
CTTCCCCCTCCCCCTACCTCCTTCCCCTCACTCCTCCCCTCCTTCGCTCGCTCAACCTCTTTTGTTCAGTATGTGTAACTTGAAGCTAAT
TTGTACTACTGGATATCTGACTGGAGCCACAGATACAGAATCTGTATTGTTCTTACTGAAACACAGCATGGAATTAACATTAAACTTAAA
TAAAACAAACCTAAATTAAAAATGCCAAATATCGCGCCTCCATCCTTTATACTTCTAAAATAAAATCTCTAGTCCAAACACACTGACAGT
ATTATGTTTGCCTGAATGTGAAACATTCCTCCTTTTTTCTTCCATAAATAATTTGTTTGCTTCCCAAAGATGTATGTTTTGGAAAAAAAT
TGCCTGTAGTCTGGTTGTGAAGAACACTGAGTCAGTTGATGGTGTGTCTTGTCCTCCAGACCAGGCAGCAACATGGTATTTATTTTAATC

>In-frame_ABR_ENST00000574437_chr17_982570_-_YWHAE_ENST00000264335_chr17_1268352_-_2906nt
ATAAAAAGCAAAATGGTGACTCAGAGAGGAGAGTTGGAAGCGTCCTGCCTCTTGCTCCCACTGTTAATTTTTACACTTGGAATTAGGCAG
AAGGCAAAGAAAACAGCAGCTTGAAATACGCGGCTGACATGCTCTTCATCGGGTAGCAACAGCAGAGCCGCTCCTCCCCGCCTCCCAGCA
GCCCCGGAGCGGGCAGGGCCCGGTGCCTGCTGGCTCTCCCCCGCCCCTCACCAGGCCCAGGCCCCCGCACAGCCCCCGCCCGGGCCAGGC
GTGGATGGTGCGGCCGGGGCCATGGCTGCCGGGGGCCGCCGCCGGCGCCCACTACGCTACCAGTCCCTGGCAGCTCTGGTGGAGGATTCT
CAGTGGCCTTTCTTGTTCCTTGTCTCAGACTTCAGCTACGGGACGGACGAGTACGACGGAGAGGGGAATGAGGAGCAGAAGGGGCCCCCG
GAGGGCTCAGAGACCATGCCGTACATCGATGAGTCGCCCACCATGTCCCCGCAGCTCAGCGCCCGCAGCCAGGGCGGGGGGGATGGCGTC
TCCCCGACTCCACCTGAGGGACTGGCTCCTGGGGTGGAAGCAGGGAAAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCC
AGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCATGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTC
ACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCTATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTG
CAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGCTGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTAT
AAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACCAGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAG
GACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGAAATGGTGGAGTCAATGAAGAAAGTAGCAGGGATGGATGTGGAGCTGACAGTT
GAAGAAAGAAACCTCCTATCTGTTGCATATAAGAATGTGATTGGAGCTAGAAGAGCCTCCTGGAGAATAATCAGCAGCATTGAACAGAAA
GAAGAAAACAAGGGAGGAGAAGACAAGCTAAAAATGATTCGGGAATATCGGCAAATGGTTGAGACTGAGCTAAAGTTAATCTGTTGTGAC
ATTCTGGATGTACTGGACAAACACCTCATTCCAGCAGCTAACACTGGCGAGTCCAAGGTTTTCTATTATAAAATGAAAGGGGACTACCAC
AGGTATCTGGCAGAATTTGCCACAGGAAACGACAGGAAGGAGGCTGCGGAGAACAGCCTAGTGGCTTATAAAGCTGCTAGTGATATTGCA
ATGACAGAACTTCCACCAACGCATCCTATTCGCTTAGGTCTTGCTCTCAATTTTTCCGTATTCTACTACGAAATTCTTAATTCCCCTGAC
CGTGCCTGCAGGTTGGCAAAAGCAGCTTTTGATGATGCAATTGCAGAACTGGATACGCTGAGTGAAGAAAGCTATAAGGACTCTACACTT
ATCATGCAGTTGTTACGTGATAATCTGACACTATGGACTTCAGACATGCAGGGTGACGGTGAAGAGCAGAATAAAGAAGCGCTGCAGGAC
GTGGAAGACGAAAATCAGTGAGACATAAGCCAACAAGAGAAACCATCTCTGACCACCCCCTCCTCCCCATCCCACCCTTTGGAAACTCCC
CATTGTCACTGAGAACCACCAAATCTGACTTTTACATTTGGTCTCAGAATTTAGGTTCCTGCCCTGTTGGTTTTTTTTTTTTTTTTTTAA
ACAGTTTTCAAAAGTTCTTAAAGGCAAGAGTGAATTTCTGTGGATTTTACTGGTCCCAGCTTTTAGGTTCTTTAAGACACTAACAGGACT
ACATAGAGGCTTTTTCAGCATTACTGTGTCGTCTCCGTGCCAGATGTGGCAAGATCACCATTAGCAAATGGAAATTACATTTGAAAGCCA
TTAGACTTATAGGTGATGCAAGCATCTAAGAGAGAGGTTAATCACACTATAGAGGCATAAGTGGTATCAGTTTTCATTTTTCTAATTGTT
TAAACTGTGTTTTATACCAGTGTTTGCAAGTAATTGGGTGTTAGCTTGAGATGGTTAAAGGTGGTTTGGGGAGGGACTTCGTTGTAATGG
TTTTGCTGTAAAAAATGTTTCCAACTCCGCTGAAATGTTGCTGAAAAGCATGGTGCTGGTAACAGTTCAACAATCCGTGGCTGCTCATTC
TTGCCTACTTTACTCTCCCACTGAAGCAGGTTAGCGTTGAAGGTGGTATGGAAAAGCCTGCATGCCTGTTCAATTCTTTTGTTTCTTCTC
CTTCCCCCTCCCCCTACCTCCTTCCCCTCACTCCTCCCCTCCTTCGCTCGCTCAACCTCTTTTGTTCAGTATGTGTAACTTGAAGCTAAT
TTGTACTACTGGATATCTGACTGGAGCCACAGATACAGAATCTGTATTGTTCTTACTGAAACACAGCATGGAATTAACATTAAACTTAAA
TAAAACAAACCTAAATTAAAAATGCCAAATATCGCGCCTCCATCCTTTATACTTCTAAAATAAAATCTCTAGTCCAAACACACTGACAGT
ATTATGTTTGCCTGAATGTGAAACATTCCTCCTTTTTTCTTCCATAAATAATTTGTTTGCTTCCCAAAGATGTATGTTTTGGAAAAAAAT
TGCCTGTAGTCTGGTTGTGAAGAACACTGAGTCAGTTGATGGTGTGTCTTGTCCTCCAGACCAGGCAGCAACATGGTATTTATTTTAATC

>In-frame_ABR_ENST00000291107_chr17_982570_-_YWHAE_ENST00000264335_chr17_1268352_-_2500nt
TTCCTGTCTGCCCTCCGCGGGCTCCGGCTGCCATGGAGGAGGAAGAGGAGGCGATAGGCTTGCTGGACAAGGTTCTGGAGGACGAAGATG
TGTTTCTCCTGGAGGAGTGCGAGCTGGGAACCCCGACCAGCCCCGGCTCAGGGTCCCCCTTCCTGGTGGCTGTGAAGGTGGAAGCAGGGA
AAGGCCTGGAGATGAGGAAGCTGGTTCTCTCGGGGTTCTTGGCCAGCGAAGAGATCTACATTAACCAGCTGGAAGCCCTGTTGCTGCCCA
TGAAACCCCTGAAGGCCACCGCCACCACCTCCCAGCCCGTGCTCACCATCCAGCAGATCGAGACCATCTTCTACAAGATCCAGGACATCT
ATGAGATCCACAAGGAGTTCTATGACAACCTGTGCCCCAAGGTGCAACAGTGGGACAGCCAGGTCACCATGGGCCACCTCTTCCAGAAGC
TGGCCAGCCAGCTCGGTGTGTACAAAGCGTTTGTCGATAACTATAAAGTCGCTCTGGAGACAGCTGAGAAGTGCAGCCAGTCCAACAACC
AGTTCCAGAAGATCTCAGAGGAACTCAAAGTGAAAGGTCCCAAGGACTCCAAGGACAGCCACACGTCTGTCACCATGGAAGAAATGGTGG
AGTCAATGAAGAAAGTAGCAGGGATGGATGTGGAGCTGACAGTTGAAGAAAGAAACCTCCTATCTGTTGCATATAAGAATGTGATTGGAG
CTAGAAGAGCCTCCTGGAGAATAATCAGCAGCATTGAACAGAAAGAAGAAAACAAGGGAGGAGAAGACAAGCTAAAAATGATTCGGGAAT
ATCGGCAAATGGTTGAGACTGAGCTAAAGTTAATCTGTTGTGACATTCTGGATGTACTGGACAAACACCTCATTCCAGCAGCTAACACTG
GCGAGTCCAAGGTTTTCTATTATAAAATGAAAGGGGACTACCACAGGTATCTGGCAGAATTTGCCACAGGAAACGACAGGAAGGAGGCTG
CGGAGAACAGCCTAGTGGCTTATAAAGCTGCTAGTGATATTGCAATGACAGAACTTCCACCAACGCATCCTATTCGCTTAGGTCTTGCTC
TCAATTTTTCCGTATTCTACTACGAAATTCTTAATTCCCCTGACCGTGCCTGCAGGTTGGCAAAAGCAGCTTTTGATGATGCAATTGCAG
AACTGGATACGCTGAGTGAAGAAAGCTATAAGGACTCTACACTTATCATGCAGTTGTTACGTGATAATCTGACACTATGGACTTCAGACA
TGCAGGGTGACGGTGAAGAGCAGAATAAAGAAGCGCTGCAGGACGTGGAAGACGAAAATCAGTGAGACATAAGCCAACAAGAGAAACCAT
CTCTGACCACCCCCTCCTCCCCATCCCACCCTTTGGAAACTCCCCATTGTCACTGAGAACCACCAAATCTGACTTTTACATTTGGTCTCA
GAATTTAGGTTCCTGCCCTGTTGGTTTTTTTTTTTTTTTTTTAAACAGTTTTCAAAAGTTCTTAAAGGCAAGAGTGAATTTCTGTGGATT
TTACTGGTCCCAGCTTTTAGGTTCTTTAAGACACTAACAGGACTACATAGAGGCTTTTTCAGCATTACTGTGTCGTCTCCGTGCCAGATG
TGGCAAGATCACCATTAGCAAATGGAAATTACATTTGAAAGCCATTAGACTTATAGGTGATGCAAGCATCTAAGAGAGAGGTTAATCACA
CTATAGAGGCATAAGTGGTATCAGTTTTCATTTTTCTAATTGTTTAAACTGTGTTTTATACCAGTGTTTGCAAGTAATTGGGTGTTAGCT
TGAGATGGTTAAAGGTGGTTTGGGGAGGGACTTCGTTGTAATGGTTTTGCTGTAAAAAATGTTTCCAACTCCGCTGAAATGTTGCTGAAA
AGCATGGTGCTGGTAACAGTTCAACAATCCGTGGCTGCTCATTCTTGCCTACTTTACTCTCCCACTGAAGCAGGTTAGCGTTGAAGGTGG
TATGGAAAAGCCTGCATGCCTGTTCAATTCTTTTGTTTCTTCTCCTTCCCCCTCCCCCTACCTCCTTCCCCTCACTCCTCCCCTCCTTCG
CTCGCTCAACCTCTTTTGTTCAGTATGTGTAACTTGAAGCTAATTTGTACTACTGGATATCTGACTGGAGCCACAGATACAGAATCTGTA
TTGTTCTTACTGAAACACAGCATGGAATTAACATTAAACTTAAATAAAACAAACCTAAATTAAAAATGCCAAATATCGCGCCTCCATCCT
TTATACTTCTAAAATAAAATCTCTAGTCCAAACACACTGACAGTATTATGTTTGCCTGAATGTGAAACATTCCTCCTTTTTTCTTCCATA
AATAATTTGTTTGCTTCCCAAAGATGTATGTTTTGGAAAAAAATTGCCTGTAGTCTGGTTGTGAAGAACACTGAGTCAGTTGATGGTGTG


Top

FusionGenePPI for ABR_YWHAE


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors
ABRLNX1, APP, ECT2, ERBB2IP, AURKB, CDKN1A, CEP250, CEP57, CEP76, TP53, MOV10, NXF1, HERC2, TRIM25YWHAEIGF1R, GPRIN2, SORBS2, GRAP2, MAPK7, NDEL1, HDAC4, HDAC5, REM1, BAD, MAP3K10, CDC25C, MAP3K3, MAP3K1, MAP3K2, IRS1, NGFRAP1, SYN2, KCNH2, TNFAIP3, RAF1, CDC25B, TOP2A, TGFB1, CDC25A, USP43, POLR3H, HDAC7, MDM4, FOXO3, HIVEP2, LRMP, COX2, MYH10, PNLIP, SSFA2, YWHAB, YWHAZ, YWHAG, ARAF, YWHAH, HDAC9, KIAA0232, TLK1, CHAF1A, CAP2, YWHAQ, RAP1GAP2, SH3BP4, WWTR1, FAM13B, MSL2, ZNF839, RASAL3, WNK1, ENKD1, TBC1D3F, CGNL1, CEP95, ANKHD1-EIF4EBP3, ING1, SRRM2, FAN1, EMD, SAMSN1, EXO1, H2AFX, MYC, PRKAA1, PARD6G, HLA-DRA, HLA-DRB1, HLA-DRB3, HLA-DRB4, HLA-DRB5, DISC1, UBE3A, GAPDH, KAT8, HIST1H3A, HIST1H4A, TCEB3, BRD4, CALM1, FBXO4, CDKN1B, TRAT1, RARRES3, ARRB1, ARRB2, CBL, ACD, POT1, CUL3, CDK2, CUL1, DCUN1D1, NEDD8, PTPN14, MARK3, MARK2, MEX3B, LRRK2, AKT1, ACTA2, CBX3, HNF1A, HSP90AB1, NPM1, ATP5B, ATP5A1, STOML2, CLNS1A, IPO8, KPNB1, RPLP0, RPL6, RPL4, RPS3, RPS8, DNAJA1, EIF4B, EIF3E, EEF1G, EEF1A2, HNRNPA2B1, ILF2, RUVBL2, RCN2, TUBB, TUBB4B, TUBB2B, PRPSAP1, TUBA3E, DDX21, ADH1B, ADH4, AGXT, HIST2H4B, HNRNPA3, HNRNPC, RBMY1A1, SF3B1, PCBP1, RBM10, MAP3K7, TBK1, PPM1B, SPIN1, CDC37, PHB, PRPSAP2, PRPS1, QPCTL, TMPO, C11orf84, HDX, CFAP43, VCP, ATXN1, FN1, VCAM1, BRAF, MAP2K1, PARD3, KIF5B, KLC2, LMO7, TBC1D4, HSPA1A, KLC3, KLC4, KLC1, CLASP2, LIMA1, TSC2, CLASP1, HSPA8, PAK4, RAB11FIP2, MAST3, TBC1D1, KIF1C, OSBPL3, TIAM1, ABLIM1, LARP1, BAIAP2, IRS2, SHROOM2, LSR, KIF1B, RAB11FIP1, MLLT4, MAST2, PFKFB2, CDK18, PKP2, DENND4A, TP53BP2, CGN, ZFP36L2, TUBA1A, KSR1, RABEP1, EIF4E2, CSNK1A1, PDZD11, PRKCI, DCAF7, NADK, USP8, C1QBP, TSC1, REEP1, KIF23, SLC25A6, SRGAP2, FAM53C, TRIP11, BCAR1, CRTC1, RASSF8, CEP250, VAMP8, GRB2, TRIM32, NOS2, IL7R, UBL4A, ITGA4, CBX4, ABL1, MST1R, PAN2, RAD52, BAG3, GSTA1, FTH1, CDK11B, SRSF1, SRSF6, SRSF4, NOLC1, TRA2B, PLEKHO2, HMHA1, SRSF7, NCBP1, DOK3, VASP, KIAA0930, GAB2, KIAA0226, PIK3R4, SGK223, RCHY1, IGHG1, UVRAG, SRSF2, FBXO6, RASSF2, SAV1, YAP1, PARK2, PAFAH1B2, PPP1R2, PROSC, RAP1GDS1, TMOD3, TNFAIP8, TUBB2A, UBXN1, VCL, XPO1, ALDH7A1, ASNS, ATIC, CAPN2, CAPNS1, EIF5, FERMT2, G6PD, GSS, ISOC1, MCTS1, STK26, OGFOD1, PAK2, PDHB, PDIA4, PTMA, SCPEP1, TBCB, TWF2, UBE2R2, IRS4, SIK3, SIK2, CEP57, TP53, GRB10, DTL, HUWE1, FBXW11, CUL7, OBSL1, CCDC8, MAST1, CDK16, TNK1, BTRC, NKD2, DMTN, TEX33, EPB41L3, WWC1, HNRNPA1, HSPB1, UNK, ACAT2, CALR, CENPE, MACF1, MAPK14, MCFD2, POLR2D, PSMB2, SHMT2, SNRPD1, ACTR6, HNRNPL, NPM3, PGK1, PSMC1, ZPR1, NTRK1, LCA5, CENPJ, PRICKLE3, MYH11, TSNAX, CCDC88A, CRY1, CRY2, MCM2, CDC5L, ERRFI1, U2AF2, PRDX6, NFATC2, SNF8, ANKZF1, SMAGP, TCEANC, LCP2, METAP2, MAGEB4, CHST11, ZC3HC1, MCM10, DDX54, C8orf59, NAF1, FGF12, GSTM3, STAC, FAM64A, ATP6V0B, FLJ25758, CDC73, WWP2, CDH1, CEP131, PCM1, PPM1H, PTPN3, SSH1, TENC1, SMTNL2, PLEKHG5, SAMD4A, SPATA13, RIN1, TFEB, TESPA1, SAMD4B, FAM163A, CRTC2, FAM189A2, PAK6, RBM3, RAB3IP, CBY1, CEP170, INPP5E, CYLD, COX15, DLD, DLST, DNM1L, SDHA, SOAT1, VDAC1, TRIM25, BRCA1, BRD1, BRMS1


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for ABR_YWHAE


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for ABR_YWHAE


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgeneABRC0033578Prostatic Neoplasms1CTD_human
TgeneYWHAEC0036341Schizophrenia4PSYGENET
TgeneYWHAEC0005586Bipolar Disorder2PSYGENET
TgeneYWHAEC0027627Neoplasm Metastasis1CTD_human