FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact

Center for Computational Systems Medicine
leaf

FusionGeneSummary

leaf

FusionProtFeature

leaf

FusionGeneSequence

leaf

FusionGenePPI

leaf

RelatedDrugs

leaf

RelatedDiseases

Fusion gene ID: 29376

FusionGeneSummary for PTMA_CREM

check button Fusion gene summary
Fusion gene informationFusion gene name: PTMA_CREM
Fusion gene ID: 29376
HgeneTgene
Gene symbol

PTMA

CREM

Gene ID

5757

1390

Gene nameprothymosin alphacAMP responsive element modulator
SynonymsTMSACREM-2|ICER|hCREM-2
Cytomap

2q37.1

10p11.21

Type of geneprotein-codingprotein-coding
Descriptionprothymosin alphagene sequence 28prothymosin alpha proteinprothymosin-I+/-cAMP-responsive element modulatorCREM 2alpha-b proteinCREM 2beta-a proteincAMP response element modulatorinducible cAMP early repressor ICER
Modification date2018052220180523
UniProtAcc

P06454

Q03060

Ensembl transtripts involved in fusion geneENST00000466801, ENST00000409321, 
ENST00000409115, ENST00000341369, 
ENST00000409683, ENST00000410064, 
ENST00000474362, ENST00000374721, 
ENST00000489388, ENST00000374726, 
ENST00000429130, ENST00000469949, 
ENST00000460270, ENST00000354759, 
ENST00000489321, ENST00000395895, 
ENST00000374728, ENST00000345491, 
ENST00000333809, ENST00000439705, 
ENST00000337656, ENST00000374734, 
ENST00000479070, ENST00000348787, 
ENST00000361599, ENST00000484283, 
ENST00000395887, ENST00000463314, 
ENST00000342105, ENST00000463960, 
ENST00000487763, ENST00000473940, 
ENST00000488328, ENST00000356917, 
ENST00000488741, ENST00000474931, 
ENST00000468236, ENST00000344351, 
ENST00000490511, 
Fusion gene scores* DoF score10 X 11 X 4=4407 X 6 X 4=168
# samples 117
** MAII scorelog2(11/440*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
log2(7/168*10)=-1.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: PTMA [Title/Abstract] AND CREM [Title/Abstract] AND fusion [Title/Abstract]

Functional or gene categories assigned by FusionGDB annotation
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCREM

GO:0006355

regulation of transcription, DNA-templated

8206879


check button Fusion gene information from three resources
(ChiTars (NAR, 2018), tumorfusions (NAR, 2018), Gao et al. (Cell, 2018))
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
Data typeSourceCancer typeSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS3.1CB985250PTMAchr2

232576688

+CREMchr10

35500204

+
* LD: Li Ding group's fusion gene list
  RV: Roel Verhaak group's fusion gene list
  ChiTaRs fusion database

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-intronENST00000466801ENST00000474362PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000374721PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000489388PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000374726PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000429130PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000469949PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000460270PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000354759PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000489321PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000395895PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000374728PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000345491PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000333809PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000439705PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000337656PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000374734PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000479070PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000348787PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000361599PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000484283PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000395887PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000463314PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000342105PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000463960PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000487763PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000473940PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000488328PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000356917PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000488741PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000474931PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000468236PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000344351PTMAchr2

232576688

+CREMchr10

35500204

+
3UTR-intronENST00000466801ENST00000490511PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000474362PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000374721PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000489388PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000374726PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000429130PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000469949PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000460270PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000354759PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000489321PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000395895PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000374728PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000345491PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000333809PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000439705PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000337656PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000374734PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000479070PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000348787PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000361599PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000484283PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000395887PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000463314PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000342105PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000463960PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000487763PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000473940PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000488328PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000356917PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000488741PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000474931PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000468236PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000344351PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409321ENST00000490511PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000474362PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000374721PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000489388PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000374726PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000429130PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000469949PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000460270PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000354759PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000489321PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000395895PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000374728PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000345491PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000333809PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000439705PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000337656PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000374734PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000479070PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000348787PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000361599PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000484283PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000395887PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000463314PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000342105PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000463960PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000487763PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000473940PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000488328PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000356917PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000488741PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000474931PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000468236PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000344351PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409115ENST00000490511PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000474362PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000374721PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000489388PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000374726PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000429130PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000469949PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000460270PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000354759PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000489321PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000395895PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000374728PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000345491PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000333809PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000439705PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000337656PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000374734PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000479070PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000348787PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000361599PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000484283PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000395887PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000463314PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000342105PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000463960PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000487763PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000473940PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000488328PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000356917PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000488741PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000474931PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000468236PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000344351PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000341369ENST00000490511PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000474362PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000374721PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000489388PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000374726PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000429130PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000469949PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000460270PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000354759PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000489321PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000395895PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000374728PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000345491PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000333809PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000439705PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000337656PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000374734PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000479070PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000348787PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000361599PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000484283PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000395887PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000463314PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000342105PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000463960PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000487763PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000473940PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000488328PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000356917PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000488741PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000474931PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000468236PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000344351PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000409683ENST00000490511PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000474362PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000374721PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000489388PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000374726PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000429130PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000469949PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000460270PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000354759PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000489321PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000395895PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000374728PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000345491PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000333809PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000439705PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000337656PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000374734PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000479070PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000348787PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000361599PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000484283PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000395887PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000463314PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000342105PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000463960PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000487763PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000473940PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000488328PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000356917PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000488741PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000474931PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000468236PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000344351PTMAchr2

232576688

+CREMchr10

35500204

+
5CDS-intronENST00000410064ENST00000490511PTMAchr2

232576688

+CREMchr10

35500204

+

Top

FusionProtFeatures for PTMA_CREM


check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
PTMA

P06454

CREM

Q03060

Prothymosin alpha may mediate immune function byconferring resistance to certain opportunistic infections.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page

.

* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

FusionGeneSequence for PTMA_CREM


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences.
(nt: nucleotides, aa: amino acids)

* Fusion amino acid sequences.

* Fusion transcript sequences (only coding sequence (CDS) region).

* Fusion transcript sequences (Full-length transcript).

Top

FusionGenePPI for PTMA_CREM


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page

.

check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

RelatedDrugs for PTMA_CREM


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.0 2018-04-02)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

RelatedDiseases for PTMA_CREM


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource
HgenePTMAC0001430Adenoma1CTD_human
HgenePTMAC0015695Fatty Liver1CTD_human
HgenePTMAC0024121Lung Neoplasms1CTD_human
HgenePTMAC0035412Rhabdomyosarcoma1CTD_human
TgeneCREMC0005586Bipolar Disorder1PSYGENET
TgeneCREMC0011875Diabetic Angiopathies1CTD_human
TgeneCREMC0020564Hypertrophy1CTD_human
TgeneCREMC0027051Myocardial Infarction1CTD_human
TgeneCREMC0036341Schizophrenia1PSYGENET
TgeneCREMC0041696Unipolar Depression1PSYGENET
TgeneCREMC0162820Dermatitis, Allergic Contact1CTD_human
TgeneCREMC0263454Chloracne1CTD_human
TgeneCREMC1269683Major Depressive Disorder1PSYGENET
TgeneCREMC3495559Juvenile arthritis1CTD_human